Chemical Biology Seminar Series 3 (CH-637) ‒ ISIC ‐ EPFL

The Chemical Biology Seminars Series is Organized by Prof. Christian Heinis, Prof. Beat Fierz and Prof. Angela Steinauer. It takes place every Tuesday at 16:15 unless otherwise indicated.

ChemBio seminar by Prof. Paola Laurino – Okinawa Institute of Science and Technology – CH 637

Title: How do proteins expand functionality? Abstract: Minimal mutations can dramatically reshape protein function, driving evolution in unexpected ways. In this talk, we explore three natural examples where a few…

20.06.2025 16:1517:15

Speaker: Prof. Paola Laurino
Location: BS 260
Category: Conferences – Seminars
Target audience: Informed public

ChemBio seminar by Dr. Anna Love – Scripps Institution of Oceanography; UC San Diego – CH 637

04.07.2025 16:1517:15

Speaker: Dr. Anna Love
Location: CE 1 2
Category: Conferences – Seminars
Target audience: Informed public

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Past seminars

2025

ChemBio Seminar by Prof. Nora Kory – Harvard T.H. Chan School of Public Health – CH637

23.05.2025 16:1517:15

Speaker: Prof. Nora Kory
Location: CE 1 5
Category: Conferences – Seminars
Target audience: Informed public

ChemBio Seminar by Prof. Arnaud Gautier (Sorbonne Université, France)

15.04.2025 16:0017:00

Location: SG 1138
Category: Conferences – Seminars
Target audience: Informed public

ChemBio Seminar by Prof. Jeremy Baskin (Cornell University, USA)

08.04.2025 16:0017:00

Location: ME B3 31
Category: Conferences – Seminars
Target audience: Informed public

ChemBio Seminar by Prof. Saranna Fanning (Harvard Medical School and Brigham & Women’s Hospital, USA)

28.03.2025 16:0017:00

Location: CE 1 1
Category: Conferences – Seminars
Target audience: Informed public

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2024

New Methods for the Chemical Synthesis of Post-Translationally Modified Peptides and Proteins

26.11.2024 16:1517:15

Speaker: Nina Hartrampf (University of Zurich)
Location: CE 1 5
Category: Conferences – Seminars
Target audience: General public

Principles of Protein Assembly in Cells – CH637

19.11.2024 16:1517:15

Speaker: Prof Emmanuel Levy
Location: BCH 1103
Category: Conferences – Seminars
Target audience: Informed public

ChemBio Seminar by Dr. Takeshi Harayama (Institut de Pharmacologie Moléculaire et Cellulaire, Université Côte d’Azur, France)

12.11.2024 15:0016:00

Speaker: Dr. Takeshi Harayama
Location: MA A1 10
Category: Conferences – Seminars
Target audience: Informed public

Solving the 50-years-old puzzle of the mechanism of tubulin detyrosination

01.10.2024 16:1517:15

Speaker: Prof. A. Tassos Perrakis – Utrecht University
Location: CH G1 495
Category: Conferences – Seminars
Target audience: General public

Accelerating protein engineering with viral-based in vivo screening and evolution technologies – CH636

06.09.2024 16:0017:00

Speaker: Prof. Bryan Dickinson
Location: BS 270
Category: Conferences – Seminars
Target audience: Informed public

Chemical Biology Seminar by Dr. Denisa Jamecna (Biochemie Zentrum Heidelberg / Osnabrück University, Germany)

28.05.2024 16:1517:15

Location: CO 120
Category: Conferences – Seminars
Target audience: Informed public

De novo lanthanide enzymes – from protein dynamics to photoredox catalysis +CH636

14.05.2024 16:1517:15

Speaker: Cathleen Zeymer
Location: MED 0 1418
Category: Conferences – Seminars
Target audience: Informed public

From post-translational modification to drug discovery

25.04.2024 10:1511:30

Speaker: Prof Edward Tate – Imperial Collegue of London
Location: CH G1 495
Category: Conferences – Seminars
Target audience: General public

A chemical biology toolbox for probing A-to-I RNA editing – CH636

16.04.2024 16:1517:15

Speaker: Prof Jennifer Heemstra
Location: CE 1 105
Category: Conferences – Seminars
Target audience: Informed public

ChemBio Seminar by Prof. Maja Köhn (University of Freiburg, Germany)

05.03.2024 16:1517:15

Location: CH B3 30
Category: Conferences – Seminars
Target audience: Informed public

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2023

ChemBio seminar by Prof. Marco Di Antonio (Imperial College London, UK) – CH-635

28.11.2023 16:1517:15

Speaker: Prof. Marco Di Antonio, Imperial College London, UK
Location: CE 1 1
Category: Conferences – Seminars
Target audience: Informed public

Machine learning based peptide design for diverse structures and functions

21.11.2023 17:1518:15

Speaker: Prof. Dr. Gaurav Bhardwaj
Category: Conferences – Seminars
Target audience: Informed public

ChemBio Seminar by Prof. Randall Peterson (University of Utah)

10.11.2023 13:0014:00

Speaker: Prof. Randall Peterson, College of Pharmacy, University of Utah, USA
Location: SV 1717
Category: Conferences – Seminars
Target audience: Informed public

ZOOM – ChemBio Seminar by Prof. Chang Liu (University of California, Irvine) – CH-635

07.11.2023 16:1517:15

Speaker: Prof Chang Liu
Category: Conferences – Seminars
Target audience: Informed public

Making it stick: how to engineer selective covalent ligands for diverse applications in biology

24.10.2023 16:1517:15

Speaker: Prof. Dr. Matt Bogyo, Stanford University
Location: CH G1 495
Category: Conferences – Seminars
Target audience: Informed public

ChemBio Seminar by Prof. Matt Shoulders (Massachusetts Institute of Technology Department of Chemistry) – CH-636

03.10.2023 16:1517:15

Location: CE 1 1
Category: Conferences – Seminars
Target audience: Informed public

Schläfli Prize 2023

28.09.2023 16:1518:00

Speaker: Michelle Frei
Location: CO 3
Category: Conferences – Seminars
Target audience: General public

Chemical approaches to decoding histone epigenetics

26.09.2023 16:1517:30

Speaker: Prof. David Li, University of Honkg Kong
Location: SV 1717
Category: Conferences – Seminars
Target audience: General public

Swiss Chemical Society (SCS) Lectureship – Prof. Scott Denmark (University of Illinois)

20.09.2023 16:1517:15

Speaker: Prof. Scott Denmark, University of Illinois at Urbana-Champaign (UIUC), USA
Location: BCH 2201
Category: Conferences – Seminars
Target audience: Informed public

ChemBio Seminar by Prof. Michael Nash (Uni Basel/ETH Zurich): "Comprehensive Mutational Profiling of Cancer Therapeutic Enzymes by Proximity-Based Sequencing

19.09.2023 16:1517:15

Speaker: Prof Michael Nash
Location: CE 1 4
Category: Conferences – Seminars
Target audience: Informed public

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2022

Illuminating the regulation of gene expression at the single‐molecule level

14.12.2022 11:1512:30

Speaker: Prof. Sebastian Deindl (Uppsala University)
Location: CH G1 495
Category: Conferences – Seminars
Target audience: General public

Mechanism and functions of nascent chromatin assembly during DNA replication

13.12.2022 16:1518:00

Speaker: Prof. Francesca Mattiroli (Hubrecht Institute)
Location: CH G1 495
Category: Conferences – Seminars
Target audience: General public

ChemBio seminar by Prof. Emily Balskus – CH-635

09.12.2022 16:1517:30

Speaker: Prof. Emily Balskus
Location: CM 1 5
Category: Conferences – Seminars
Target audience: Informed public

Protein domain mimics as rationally designed modulators of biomolecular function

06.12.2022 16:1517:15

Speaker: Prof. Dr. Paramjit Arora, New York University
Category: Conferences – Seminars
Target audience: Informed public

Organic Chemistry Seminar by Prof. Jakub Svenda – CH-635

30.11.2022 16:1517:15

Speaker: Prof. Jakub Svenda Masaryk University, Czech Republic
Location: BCH 2201
Category: Conferences – Seminars
Target audience: Informed public

ChemBio e-seminar by Prof. Xiao Wang – CH-635

29.11.2022 16:1517:15

Speaker: Prof. Xiao Wang Massachussetts Institute of Technology, USA
Category: Conferences – Seminars
Target audience: Informed public

Probing life and death decisions with synthetic protein chemistry

22.11.2022 16:1518:00

Speaker: Prof. Manuel Müller (King’s College London)
Location: CH B3 31
Category: Conferences – Seminars
Target audience: General public

2022 International Symposium on Chemical Biology

08.11.202210.11.2022 15:0017:00

Speaker: 15 international leaders in the field of chemical biology
Location: Campus Biotech & online
Category: Conferences – Seminars
Target audience: Expert

ChemBio e-seminar by Prof. Ken Yokoyama

25.10.2022 16:1517:15

Speaker: Prof. Ken Yokoyama Duke University, North Carolina, USA
Category: Conferences – Seminars
Target audience: Informed public

Towards Covalent Inhibitors Addressing Diverse Amino Acids – Unbiased Profiling of the Proteome-Wide Selectivity of Electrophiles

18.10.2022 11:1512:15

Speaker: Prof. Stephan Hacker (Leiden University)
Location: CH G1 495
Category: Conferences – Seminars
Target audience: General public

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2021

Understanding and predicting cell permeability of compounds in the beyond rule of 5 space

07.12.2021 16:1517:15

Speaker: Prof. Jan Kihlberg, Uppsala University
Category: Conferences – Seminars
Target audience: Informed public

Translational chemical biology

29.11.2021 16:1517:15

Speaker: Prof. Gonçalo Bernardes University of Cambridge, UK
Category: Conferences – Seminars
Target audience: Informed public

ChemBio Seminar: Natural Product Diversity in Interacting Microbes

16.11.2021 16:1517:30

Speaker: Prof. Pierre Stallforth, HKI Jena, Germany
Location: Online only!! & Online
Category: Conferences – Seminars
Target audience: Informed public

Flycodes: barcoding designer peptides for mass spectrometry enable in vivo antibody screening

02.11.2021 16:1517:45

Speaker: Prof. Markus Seeger (IMM – Universität Zürich)
Location: CH G1 495
Category: Conferences – Seminars
Target audience: General public

ChemBio e-seminar by Dr. Jordan Meier (NIH National Cancer Institute): New Insights into Acetylation & Oncometabolites from Chemoproteomics

19.10.2021

Speaker: https://ccr.cancer.gov/staff-directory/jordan-l-meier#staff-profile-lab-life-tab-9
Category: Conferences – Seminars
Target audience: Informed public

Joint ChemBio & ChemE e-seminar by Prof. Wenjun Zhang (UC Berkeley): Discovery, Biosynthesis and Functional Study of Natural Products

05.10.2021 16:1517:15

Speaker: https://chemistry.berkeley.edu/faculty/cbe/zhang
Category: Conferences – Seminars
Target audience: Informed public

ChemBio e-seminar by Prof. Sarah Slavoff (Yale University): Dark Matter of the Human Genome

28.09.2021 16:1517:15

Speaker: https://chem.yale.edu/people/sarah-slavoff
Category: Conferences – Seminars
Target audience: Informed public

Chemical Evolution of Natural Product Structure

21.09.2021 16:1517:15

Speaker: Prof. Herbert Waldmann, Max Planck Insitute of Molecular Physiology
Category: Conferences – Seminars
Target audience: Informed public

Circluar Chemistry – On the Magic of Molecular Rings

25.05.2021 16:1517:15

Speaker: Prof. Dr. Felix Hausch, Technical University of Darmstadt
Category: Conferences – Seminars
Target audience: Informed public

Sliding, Pushing, Crashing: the Treacherous Pathways of Chromosome Replication in a Crowded World

11.05.2021 16:1517:30

Speaker: Karl Duderstadt (MPI Biochemistry, München)
Category: Conferences – Seminars
Target audience: General public

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2020

Unravelling the poly(ADP-ribose) code: How the structural diversity of the post-translational modification poly(ADP-ribose) affects biochemical and biological processes

15.12.2020 15:0016:15

Speaker: Prof. Aswin Mangerich (Universität Konstanz)
Category: Conferences – Seminars
Target audience: General public

Controlling Labile Metal Ions in Biological Systems

08.12.2020 17:3018:30

Speaker: Prof. Justin Wilson, Department of Chemistry and Chemical Biology, Cornell University, USA.
Location: Zoom & Online
Category: Conferences – Seminars
Target audience: Expert

Chemical control of cellular signaling

01.12.2020 16:1517:30

Speaker: Prof. Christina Woo, Department of Chemistry and Chemical Biology, Harvard University, USA.
Location: Zoom & Online
Category: Conferences – Seminars
Target audience: Expert

Integrative dynamic structural biology of biomolecular assemblies resolved by multi-scale super-resolution FRET spectroscopy and imaging

24.11.2020 17:1518:15

Speaker: Claus A.M. Seidel (Heinrich Heine University, Germany)
Category: Conferences – Seminars
Target audience: General public

Breaking the rules with natural and non-natural cyclic peptides

17.11.2020 16:1517:15

Speaker: Prof. Scott Lokey, UC Santa Cruz
Location: Zoom & Online
Category: Conferences – Seminars
Target audience: Informed public

Automation + Miniaturization = Acceleration

03.11.2020 16:1517:15

Speaker: Prof. Alexander Dömling, University of Groningen
Location: Zoom & Online
Category: Conferences – Seminars
Target audience: Informed public

'Thiol-based Redox Signaling'

13.10.2020

Speaker: PD Dr. Tobias P. Dick, German Cancer Research Center (DKFZ), Heidelberg.
Category: Conferences – Seminars
Target audience: Expert

Chemical proteome mining to fight multiresistant bacteria

29.09.2020 09:2018:00

Speaker: Prof. Dr. Stephan Sieber Professor and Chair of Organic Chemistry II Technical University of Munich
Category: Conferences – Seminars
Target audience: General public

'Mapping biochemical drivers of phenotypic change'

01.07.2020 16:1517:30

Speaker: Prof. Daniel F. Jarosz, Associate Professor of Chemical and Systems Biology and of Developmental Biology at Stanford University, USA.
Category: Conferences – Seminars
Target audience: Expert

Harnessing massive peptide libraries to explore the inhibition of epigenetic drug targets

30.06.2020 16:0017:45

Speaker: Prof. Louise Walport
Category: Conferences – Seminars
Target audience: General public

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2019

Reprogramming the reactivity of iron in cancer

15.10.2019 16:3017:30

Speaker: Raphaël Rodriguez
Location: BCH 2201
Category: Conferences – Seminars
Target audience: General public

Redox signaling mechanisms under infection conditions and antibiotics in the major pathogen Staphylococcus aureus

01.10.2019 16:3018:00

Speaker: Prof. Haike Antelmann
Location: BCH 2201
Category: Conferences – Seminars
Target audience: General public

NMR-based tools for structural biology in gels and cells

20.09.2019 11:1512:30

Speaker: Prof. Galia Debelouchina, UCSD – University of California San Diego
Location: BCH 3303
Category: Conferences – Seminars
Target audience: Informed public

A cyclic peptide toolkit to modulate PADI4 activity

03.07.2019 10:0011:00

Speaker: Dr. Louise Walport
Location: BCH 5310
Category: Conferences – Seminars
Target audience: Informed public

Protein Epitope Mimetics: from Discovery to the Clinic

02.07.2019 16:0017:00

Speaker: Dr. Daniel Obrecht, CSO Polyphor
Location: CH G1 495
Category: Conferences – Seminars
Target audience: General public

Roles of ZRANB3 in replication stress response

07.05.2019 16:1517:15

Speaker: Professor Dragana Ahel (University of Oxford)
Location: SV 1717
Category: Conferences – Seminars
Target audience: General public

Adventures in Targeting Protein Lipdation: Breaking Drug Resistance Using Chemical Biology

09.04.2019 15:1516:15

Speaker: Prof. Edward Tate (Imperial College London)
Location: CH G1 495
Category: Conferences – Seminars
Target audience: General public

Dynamic chaperone–client-interactions characterized at atomic resolution

09.04.2019 16:4518:00

Speaker: Prof. Sebastian Hiller (University of Basel)
Location: CH G1 495
Category: Conferences – Seminars
Target audience: General public

dNTPs and maintenance of genome stability

26.02.2019 17:1518:15

Speaker: Professor Andrei Chabes Dept. of Medical Biochemistry and Biophysics Umeå University SE 901 87 Umeå Sweden Phone: +46 73 620 5446
Location: BCH 2218
Category: Conferences – Seminars
Target audience: General public

Developing small molecule catalysts for chemical protein degradation

19.02.2019 16:1517:15

Speaker: Prof. Dennis Gillingham
Location: BCH 3118
Category: Conferences – Seminars
Target audience: General public

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2018

Inaugural lecture // Membrane Proteins: from Structure Prediction to Designing Novel Functions

06.12.2018 17:1518:15

Speaker: Prof. Patrick Barth, Institute of Bioengineering, EPFL
Location: SV 1717
Category: Inaugural lectures – Honorary Lecture
Target audience: General public

Activation of transcription factor Nrf2 as a strategy to restore the cellular redox and protein homeostasis

04.12.2018 16:1517:15

Speaker: Albena T. Dinkova-Kostova
Location: BCH 2201
Category: Conferences – Seminars
Target audience: General public

The CRL4 ubiquitin ligase: at the intersection of genome stability and drug discover

23.10.2018 16:1517:00

Speaker: Prof. Nicolas Thomä, FMI Basel, Switzerland
Location: BCH 2201
Category: Conferences – Seminars
Target audience: General public

Ubiquitin E3 ligase activity-based profiling: from Parkin to the impalpable

16.10.2018 17:1518:15

Speaker: Prof. Satpal Virdee (University of Dundee)
Location: BCH 2218
Category: Conferences – Seminars
Target audience: General public

Peptides and Peptidomimetics for Selective Anion Recognition in Aqueous Solution

02.10.2018 14:0015:00

Speaker: Prof. Kate Jolliffe, (The University of Sydney, Australia)
Location: BCH 3118
Category: Conferences – Seminars
Target audience: General public

Genetic code expansion for temporal controlled labeling of endogenous expressed proteins

05.09.2018 16:1517:00

Speaker: Prof. Matthias Meier, Helmholtz Zentrum, Muenchen
Location: BCH 4310
Category: Conferences – Seminars
Target audience: General public

Transcriptional control in time and space

10.07.2018 09:0010:30

Speaker: Nadine L. Vastenhouw (MPI Molecular Cell Biology and Genetics – Germany)
Location: SV 1717
Category: Conferences – Seminars
Target audience: Expert

PROTAC-mediated Protein Degradation: The chemical equivalent of siRNA

21.06.2018 16:0017:00

Speaker: Prof. Craig Crews, Yale University
Location: BCH 2218
Category: Conferences – Seminars
Target audience: Informed public

"Protein Self-Assembly by Chemical Design"

20.06.2018 11:0012:30

Speaker: Akif Tezcan, UCSD
Location: BCH 3118
Category: Conferences – Seminars
Target audience: General public

Expanding the Genetic Code – Chemistry in Living Systems

15.05.2018 17:1518:15

Speaker: Prof. Kathrin Lang (TU Munich)
Location: BCH 2218
Category: Conferences – Seminars
Target audience: Informed public

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2017

Decoding chromatin modification states using chemical biology and proteomic approaches

12.12.2017 15:1517:00

Speaker: Prof. Till Bartke, Institute of Functional Epigenetics Helmholtz Zentrum München
Location: BCH 5310
Category: Conferences – Seminars
Target audience: General public

Selective chemical intervention on protein-protein interactions: from inhibitors to degraders

17.10.2017 16:1518:00

Speaker: Prof. Alessio Ciulli, University of Dundee
Location: BCH 2218
Category: Conferences – Seminars
Target audience: General public

Peptide‐based probes for lysine deacetylases

20.09.2017 15:0016:30

Speaker: Prof. Dirk Schwarzer, Universität Tübingen
Location: BCH 2218
Category: Conferences – Seminars
Target audience: General public

Molecular mechanisms of epigenetic regulation

11.09.2017 16:1518:00

Speaker: Prof. Tatiana Kutateladze Department of Pharmacology University of Colorado School of Medicine, Aurora, Colorado, USA
Location: SV1717.A
Category: Conferences – Seminars
Target audience: Informed public

X-Ray Crystal Structure of a Chromatosome—the Fundamental Nucleosome-Linker Histone Assembly of Chromatin

22.06.2017 11:0012:30

Speaker: Prof. Curtis Davey (NTU – Singapore)
Location: CH G1 495
Category: Conferences – Seminars
Target audience: Expert

An iron hand over cancer stem cells

27.04.2017 16:1518:00

Speaker: Prof. Raphael Rodriguez, Institut Curie, Paris
Location: BCH 2218
Category: Conferences – Seminars
Target audience: General public

Probing unfolded and intrinsically disordered proteins with single-molecule spectroscopy

06.04.2017 15:0016:15

Speaker: Prof. Ben Schuler, University of Zurich
Location: BCH 2218
Category: Conferences – Seminars
Target audience: General public

EPIGENETIC REGULATION OF CHROMATIN DYNAMICS

20.01.2017 11:0012:00

Speaker: Prof. Michael Poirier, Ohio Stat University
Location: CH G1 495
Category: Conferences – Seminars
Target audience: General public

The power of chemoselectivity: Functional protein-conjugates for proteomic and pharmaceutical research

19.01.2017 11:0012:30

Speaker: Prof. Christian Hackenberger, Humboldt Universität zu Berlin and Leibniz-Institut für Molekulare Pharmakologie (FMP) – Berlin
Location: CH G1 495
Category: Conferences – Seminars
Target audience: General public

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