Polina Shichkova is a PhD student in the Molecular Systems group within the Simulation Neuroscience division.
She focuses on molecular atlas of neuroglia: data integration for protein and metabolite concentrations and, NGV metabolism reconstruction and simulation: detailed data driven reconstruction and simulation with the focus on energy metabolism.
Polina has a BSc and MSc in Applied Mathematics and Physics from Moscow Institute of Physics and Technology, Moscow, Russia. In addition, she has an MSc in Biotechnology from the Skolkovo Institute of Science and Technology, Moscow, Russia.
Polina’s projects during her studies were related to bioinformatics, systems biology and rational drug design. She also worked on molecular modeling for biological visualization of CRISPR-Cas systems in a joint project between Skolkovo Institute of Science and Technology and Visual Science company. (https://www.visual-science.com/projects/crispr/animation/ )
In 2017, at the Hackathon LauzHack Lausanne she was part of the team that won the SGS challenge.
In her spare time, she enjoys dance (especially ballet), drawing, piano, rock climbing, yoga and snowboarding.
Cellular, synaptic and network effects of acetylcholine in the neocortex. Colangelo C., Shichkova P., Keller D., Markram H., Ramaswamy S. Front. Neural Circuits 2019 doi: 10.3389/fncir.2019.00024 https://www.frontiersin.org/articles/10.3389/fncir.2019.00024/full
Anti-leprosy drug clofazimine inhibits growth of triple-negative breast cancer cells via inhibition of canonical Wnt signaling. Koval A.V., Vlasov P., Shichkova P., Khunderyakova S., Markov Y., Panchenko J., Volodina A., Kondrashov F.A., Katanaev V.L. 2014, Biochem. Pharmacol https://www.ncbi.nlm.nih.gov/pubmed/24355563
Biorxiv: Genomic analysis of human polymorphisms affecting drug-protein interactions. O Pich i Rosello, AV Vlasova, PA Shichkova, Y Markov, PK Vlasov, FA Kondrashov 2017 Biorxiv https://www.biorxiv.org/content/10.1101/119933v1