Gene Expression Core Facility

DNA molecules (Adobe education license)


We provide a diverse set of tools for the functional and quantitative analysis of genomes and transcriptomes, both at single cells level or on bulk cell populations. This comprises in particular next-generation sequencing, classical or high-throughput microfluidics-based qPCR technologies, digital PCR, and spatial transcriptomics analyses. In addition, we enable manipulation of the cellular gene expression program by providing different genome-wide collections of ORFs. Because new technologies constantly emerge, we are eager to discuss means to further improve and develop our toolbox.


Next generation sequencing

Illumina (MiSeq, NextSeq, NovaSeq) or Elembio (Aviti) short reads. Oxford Nanopore long reads (MinION, Promethion)

Single cells genomics/ transcriptomics

10X Genomics ChromiumX, Parse…

Spatial Transcriptomics

10X Genomics Visium / CytAssist

Quantitative and digital PCR

Classical qPCR (Applied Biosystems QuantStudio), microfluidics-based qPCR (Fluidigm BioMark), and digital PCR (Qiagen Qiacuity)

Nucleic acids QC

Profiling (TapeStation 4200 and Fragment Analyzer) and quantification (Qubit, Nanodrop One)

ORF & cDNA Collections

We manage and distribute several large collections of ORFs


April 2024

  • Visium HD is here! Spatial transcriptomics resolution is now down to single cell scale, more info here!

March 2024

  • Our new Aviti sequencer is operational. Please inquire. More news soon anyway.

January 2024

November 2023

  • New price list available here, with decrease of fixed RNA 10XG (FLEX) prices

October 2023

July 2023

  • New price list available here! Many new services included. Price decrease of NovaSeq runs.

June 2023

April 2023

  • We have just launched a HiC libraries prep service, based on Arima workflow. Inquire for pricing and details.
  • A new libraries submission form is available here (together with updated guidelines).

February 2023


  • From now on please use our team email address [email protected] for projects submissions and other demands.
  • New versions of our libraries submission form/guidelines are available here.
  • We have launched our NovaSeq 6000 service! Please inquire.


  • We have launched a Visium FFPE spatial transcriptomics service, in collaboration with HCF.
  • A NovaSeq 6000 will soon replace our HiSeq 4000! More news in December.
  • A warm welcome to our new collaborator Chiara Sartori.
  • The replacement process for our HiSeq 4000 sequencer has begun, more news in 2 months.
  • Our new 10X Genomics single cell multiome (scATAC-seq+scRNA-seq) and CellPlex services are operational.
  • Our new QuantStudio 6 instrument is now operational.
  • Our new web tool CloneMap for ORFs browsing and QC is operational (thanks Fabrice David).
  • A warm welcome to our new collaborator Patricia Hornitschek.




  • Our new HiSeq 4000 sequencer just arrived! Service will begin later in January.
  • We released libraries submission guidelines for NextSeq sequencing. They are available here.
  • We released RNA submission guidelines for RNA-seq, and gDNA submission guidelines for whole genome sequencing or exome sequencing. They are available here.
  • A slightly updated version of our price list is available here.
  • Our new 10X Genomics Chromium instrument is operational. This allows scaling up single cells transcriptomics experiments to thousands of cells.
  • New user-friendly short protocols are available for the TapeStation 4200.



  • Initial release of our new MOUSAIC collection of murine ORFs.
  • New improved versions of the Fragment Analyzer kits were released.
  • Our new Agilent TapeStation 4200 has arrived. This RNA/DNA profiling instrument nicely complements our Fragment Analyzer. Please contact us for more details.