Swiss Institute for Experimental Cancer Research ‐ EPFL

Spanning basic and translational cancer research to fundamental cell and developmental biology.

Molecular Cell Biology of Development and Cancer

Basic and Translational Cancer Research

Paternot Faculty Chair in Interdisciplinary Cancer Research

Invasive Lobular Carcinoma Intraductal Xenograft Tissue Section Stained for Fibrillar Collagen. Credit: George Sflomos (EPFL)

Scientists model a peculiar type of breast cancer

Published:24.02.21 — Scientists led by EPFL have developed a breakthrough in vivo model for invasive lobular carcinoma, a serious yet understudied type of breast cancer. The work will open up previously inaccessible study of the tumor’s biology and help discover new therapies.

A screenshot of MarrowQuant annotating a bone marrow trephine biopsy from a patient surfing from chemotherapy-induced aplasia. Credit: Olaia Naveiras (EPFL)

MarrowQuant: a digital-pathology tool

Published:29.09.20 — EPFL scientists have developed a digital pathology workflow for quantifying bone marrow compartments in standard histological sections. Named “MarrowQuant”, this workflow based on the open source software QuPath makes it possible to examine bone marrow biopsies as well as to re-examine historical collections of bone-marrow samples and even old clinical trials.

The “G” represents the highly expressed glucose transporters Glut1 and Glut3 in lung adenocarcinomas. Left: the dual deletion impairing lung tumor growth. Credit: Liloon (Julie de Meyer)

Blocking sugar metabolism slows lung tumour growth

Published:23.06.20 — Treatments that block two sugar-transporting proteins could help slow the growth of lung tumours, new research from EPFL suggests.

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