Swiss Institute for Experimental Cancer Research

Cancer: A mutation that breaks gene interplay in 3D

Published:30.01.19 — EPFL scientists have discovered how a mutated gene can affect the three-dimensional interactions of genes in the cell, leading to various forms of cancer.

Tumors backfire on chemotherapy

Published:10.01.19 — Chemotherapy is an effective treatment for breast cancer, yet some patients develop metastasis in spite of it. Researchers at EPFL have discovered that chemotherapy-treated mammary tumors produce small vesicles that may help them spread to other organs. The study is published in Nature Cell Biology.

Hidden estrogen receptors in the breast epithelium

Published:12.11.18 — EPFL scientists have uncovered that next to estrogen receptor-positive and -negative cells, there are cells with very low amounts of the receptor protein. The discovery has significant implications for the role of the receptor in the growth and development of the breast and breast cancer.