ISREC – Swiss Institute for Experimental Cancer Research

Spanning basic and translational cancer research to fundamental cell and developmental biology.

Molecular Cell Biology of Development and Cancer

The “G” represents the highly expressed glucose transporters Glut1 and Glut3 in lung adenocarcinomas. Left: the dual deletion impairing lung tumor growth. Credit: Liloon (Julie de Meyer)

Blocking sugar metabolism slows lung tumour growth

Published:23.06.20 — Treatments that block two sugar-transporting proteins could help slow the growth of lung tumours, new research from EPFL suggests.

How accurate are transcription factor binding-site motifs?

Published:12.06.20 — An international team led by researchers from EPFL and the Russian Academy of Sciences have undertaken a comprehensive benchmarking study to assess the predictive performance of publicly available transcription factor binding site motifs.

A neutrophil interacting with SARS-CoV2. Credit: Adobe Stock Photos

A better model for neutrophil-related diseases

Published:02.06.20 — Neutrophils are critical immune cells for antimicrobial defense, but they can exacerbate a number of diseases, perhaps including COVID-19. The traditional approaches to study neutrophils in animal models are limited in specificity and effectiveness. EPFL scientists have now identified the problem and have developed a new, optimized model for studying the role of neutrophils in the context of disease.

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