Vignayanandam Ravindernath Muddapu

Simulation Neuroscience Circuits


Vignayanandam Ravindernath Muddapu is a Postdoctoral Fellow in the Circuits team in the Simulation Neuroscience Division.


Vignan is currently working on the harvestation of the Thalamus, Somatosensory Cortex (SSCx) and Neocortex (NCx) models.

Before joining the Blue Brain, he was the team leader of basal ganglia group in Computational Neuroscience Lab at Indian Institute of Technology Madras, India.

Vignan has a Ph.D. in Computational Neuroscience from Indian Institute of Technology Madras, Chennai, India and, gained his integrated (BS-MS) Masters in Systems Biology, from University of Hyderabad, India.

During his research, he was the recipient of part-time, five year, Research Assistant fellowship from the Government of India and received Department of Science and Technology and Council of Scientific and Industrial Research travel grants sponsored by the Government of India. He was awarded best paper presentation at BITS Pilani-Hyderabad and won a five year, BBL scholarship at the University of Hyderabad.

In his free time, Vignan goes hiking, and enjoys photography and traveling.

Selected Publications

Vignayanandam R. Muddapu, & V. Srinivasa Chakravarthy (2021) Influence of Energy Deficiency on the Subcellular Processes of Substantia Nigra Pars Compacta Cell for Understanding Parkinsonian Neurodegeneration, Scientific Reports.

Vignayanandam R. Muddapu, & V. Srinivasa Chakravarthy (2020) A Multi-Scale Computational Model of Excitotoxic Loss of Dopaminergic Cells in Parkinson’s Disease, Frontiers in Neuroinformatics.

Vignayanandam R. Muddapu, S. Akila P. Dharshini, V. Srinivasa Chakravarthy, & M. Michael Gromiha (2020) Neurodegenerative diseases -Is metabolic deficiency the root cause?, Frontiers in Neuroscience| Neurodegeneration.

Vignayanandam R. Muddapu, Alekhya Mandali, V. Srinivasa Chakravarthy, & Srikanth Ramaswamy (2019) A computational model of loss of dopaminergic cells in Parkinson’s disease due to glutamate-induced excitotoxicity, Frontiers in Neural Circuits.