Sofia Farina

Simulation Neuroscience
Molecular Systems



Sofia Farina is a Postdoctoral Researcher in the Molecular Systems team in the Simulation Neuroscience Division.

At Blue Brain, Sofia’s research focuses on the simulation of the Neuro-Glia-Vascular (NGV) system. In her Ph.D. studies prior to joining Blue Brain, Sofia investigated the coupling between metabolism and morphology of astrocytes through a spatially resolved metabolic model solved in 3D human astrocytic images. She also investigated the interplay between metabolism and calcium signaling.

Sofia studied Mathematics at the University of Bologna where she obtained both her Bachelor’s and Master’s degree. She then pursued a Ph.D. in Engineering Science from the University of Luxembourg in collaboration with the Luxembourg Center for Systems Biomedicine.

In her free time, Sofia enjoys climbing, skiing, reading, cooking, and traveling.

Selected Publications

Farina, S., Voorsluijs, V., Fixemer, S., Bouvier, D., Claus, S., Ellisman, M., Bordas, S.P. and Skupin, A., Mechanistic multiscale modelling of energy metabolism in human astrocytes reveals the impact of morphology changes in Alzheimer’s Disease. PLOS Computational Biology (2023)

Farina, S., Claus, S., Hale, J.S., Skupin, A. and Bordas, S.P., A cut finite element method for spatially resolved energy metabolism models in complex neuro-cell morphologies with minimal remeshing. Advanced Modeling and Simulation in Engineering Sciences (2021)