What is the EPFL Blue Brain Project?
The EPFL Blue Brain Project is a Swiss National Research Infrastructure project, hosted by the École Polytechnique Fédérale de Lausanne and supported and funded by the Swiss government (ETH Board).
First digital 3D atlas of every cell in the 737 regions in the mouse brain
Open source repositories and nine major libraries
Registrations for BBP MOOCs
Public dissemination and outreach events in 2019
Employees from around the world
Blue Brain Press Releases and News
Why do some people get sick and die from COVID-19 while others seem to be completely unaffected? EPFL’s Blue Brain Project deployed its powerful brain simulation technology and expertise in cellular and molecular biology to try and answer this question. A group in the Blue Brain assembled an AI tool that could read hundreds of thousands of scientific papers, extract the knowledge and assemble the answer – A machine-generated view of the role of Blood Glucose Levels in the severity of COVID-19 was published today by Frontiers in Public Health.
The Blue Brain Project follows a four-year roadmap with specific scientific milestones to achieve its ultimate goal, digitally reconstructing and simulating the entire mouse brain. One of the goals in the current period is to model structures with direct relevance for the neocortex. The thalamus is highly interconnected with the cortex and plays an important role in an array of cognitive processes. It funnels sensory input to the neocortex with the thalamocortical loop playing a central role in cerebral rhythmogenesis (biological rhythm). As such, it has a key role in many functions, such as sleep and wakefulness and is involved in various diseases associated with dysfunction of rhythmic activity such as epilepsy, autism, schizophrenia and bipolar disorder. However, there is much that scientists do not know about this brain region and as the understanding of the thalamocortical system deepens, so does the complexity of the questions scientists face.
Recognizing the importance of understanding the structural and biochemical basis of astrocyte-mediated neuronal energy metabolism in the mammalian brain, the King Abdullah University of Science and Technology (KAUST) and EPFL Blue Brain Project Alliance was set up in 2013 to focus on this area of brain research.
The collaboration recently held a two-day online workshop – Integrative Modeling of Brain Energy Metabolism, whichhighlighted and shared the achievements to date of this dynamic Alliance. Attended by hundreds from all over the world, the workshop also enabled the participants to hear from global experts in the field on the future directions of this research.
Blue Brain Portal
The Blue Brain Portal is a knowledge space for neuroscientists. EPFL’s Blue Brain Project recognizes that knowledge sharing is an important driving force to consolidate and promote simulation neuroscience, which in turn, is fundamental to understanding the brain as a complex multi-scale system. Therefore, the Blue Brain Portal brings together in one place open-sourced software, tools, models and data, both from us and our collaborators. The aim is for this knowledge to be utilized by both the neuroscientific and the wider scientific community to develop the field of simulation neuroscience.
Join Blue Brain’s journey to digitally reconstruct and simulate the brain.