Press Resources

What is the EPFL Blue Brain Project?

The EPFL Blue Brain Project is a Swiss National Research Infrastructure project, hosted by the École Polytechnique Fédérale de Lausanne and supported and funded by the Swiss government (ETH Board).


Neurons modelled


Synapses modelled


Open access shared – million-plus Kv channel recordings from over 18,000 cells


First digital 3D atlas of every cell in the 737 regions in the mouse brain


Open source repositories and nine major libraries


Blue Brain has published over 230 papers and pre-prints in scientific journals


Registrations for BBP MOOCs


Public dissemination and outreach events in 2019


Employees from around the world



Blue Brain Press Releases and News

© 2022 EPFL

STEPS 4.0 towards large-scale biologically-relevant simulations


Simulating neurons down to the level of their biochemistry in order to understand their behavior and properties is a complex computational challenge. While small to the human eye, a neuron is a comparatively large object relative to its biochemical constituents. Yet, the overall behavior of a neuron depends on the specific composition and interactions at the molecular level that will control its electrical properties. It’s like aiming to fully describe a patch of forest down to the millimeter, recording the location and shape not only of each tree and each leaf, but of each grain of dirt. Even with high performance computing and ever increasing computing power, scientists still have to make uncomfortable compromises; phenomena that are random in nature are averaged out for ease of calculation, or only parts of a cell can be described with molecules and their interactions. Needing to choose between what is biologically relevant and what is able to be addressed, leads to significant loss of information and, often, relevance. Now, teams from the EPFL Blue Brain Project and from the Okinawa Institute of Science and Technology Graduate University, Japan (OIST) describe how they pushed the boundaries of simulating biochemical diffusion-reaction models to the scale of entire neurons. The new solution dramatically reduces the computer memory needed while maintaining similar or better performance, increasing overall scalability.

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Blue Brain Portal

The Blue Brain Portal is a knowledge space for neuroscientists. EPFL’s Blue Brain Project recognizes that knowledge sharing is an important driving force to consolidate and promote simulation neuroscience, which in turn, is fundamental to understanding the brain as a complex multi-scale system. Therefore, the Blue Brain Portal brings together in one place open-sourced software, tools, models and data, both from us and our collaborators. The aim is for this knowledge to be utilized by both the neuroscientific and the wider scientific community to develop the field of simulation neuroscience.

Join Blue Brain’s journey to digitally reconstruct and simulate the brain.

About the Blue Brain and our open source tools, software & databases

Director Profiles

Prof. Henry Markram

Founder and Director
Director of Simulation Neuroscience

Prof. Felix Schürmann

Director of Computing
Blue Brain Co-Director

Adriana Salvatore

Director of Operations
Blue Brain Co-Director

Media contact

For any press enquiries on the Blue Brain contact:
email: Evelyne Schmid Osborne, Communications Manager