Welcome to LCSO!

Synthesis of metal complexes, ligands, and organocatalysts. New catalytic reactions for C-C bond formation. Investigation of reactions mechanism. Synthesis of complex bioactive compounds.

Our group is driven by the passion of discovering new reactivity in organic chemistry, especially using catalysis. Basing on high energy molecules, such as strained rings or cyclic hypervalent iodine reagents for electrophilic alkynylation and other transformations, we develop non-conventional bond disconnections for the synthesis of important building blocks and bioactive molecules, as well as the modification of biomolecules . We also control the regioselective functionalization of alkenes and alkynes using in situ tethering approaches. Regular group meetings and seminars allow us to share and enhance our knowledge and love of organic chemistry.


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Latest News

February 8: Welcome to Tin Nguyen, our new PhD student from the Ecole Polytechnique and Paris Sarclay University and Emma Robert, our new master student from Ecole Supérieure CPE Lyon.

January 15: The last results of Elija and Javier in collaboration with the Heinis group on new hypervalent iodine reagents for cys-cys and cys-lys peptide stapling have appeared in Angewandte Chemie (DOI: 10.1002/anie.202014511).

January 11: Welcome to Pierre Palamini, our new PhD student from the Ecole Normale Supérieure de Chime de Montpelier.

January 7: The last results of Eliott and Marion on the photoredox-catalyzed oxidative functionalization of small peptides have appeared in Chemical Science (DOI: 10.1039/D0SC06180H).

December 10: The first online LCSO Alumni meeting has taken place in replacement of the traditional Christmas dinner canceled due to COVID reasons.

December 3: Bastian Muriel has successfully passed his PhD exam. Congratulations!

November 21: The last results of Durga, Guillaume, Matt and Artem on a [4+2] annulation reaction with benzene proceeding at room temperature have appeared in Angewandte Chemie (DOI: 10.1002/anie.202012299).

November 18: The last results of Bastian on the reaction of azide radicals with cyclopropenes have appeared in Angewandte Chemie (DOI: 10.1002/anie.202013516).

November 12: Marion Garreau successfully defended her PhD thesis. She is the fifteenth PhD student to obtain their degree at LCSO. Congratulations!

November 12: Welcome to Diana Cavalli, our new PhD student from the University of Basel.

November 10: The personal account of Stefano, Ugo, Bastian, Phill, Luca and Mikus on palladium-catalyzed alkenes and alkynes functionalization has appeared in Synlett in the special issue dedicated to Prof. Trost (DOI: 10.1055/a-1308-0021).

November 10: The last results of Ming-Ming and Seongmin on annulation reaction of aminocyclopropanes have appeared in Organic Letters (DOI: 110.1021/acs.orglett.0c03528).

October 30: Luca has won a poster award at the online Industrial Chemistry Symposium. Congratulations!

October 30: The review of Nina and Guillaume on vinylbenziodoxolone (VBX) reagents has now appeared in Helvetica Chimica Acta in the special issue dedicated to Prof. Togni (DOI: 10.1002/hlca.202000191).

October 14: Marion Garreau has successfully passed her PhD exam. Congratulations!

October 3: The last results of Luca, Mikus and Phill on catalytically formed chiral auxiliaries for amino alcohol synthesis have now appeared in the Journal of the American Chemical Society (DOI: 10.1021/jacs.0c09177).

September 23: Welcome to Xingyu Liu, our new PhD student from the Shanghai Institute of Organic Chemistry.

September 22: Mikus and Julien have successfully passed their first year candidacy exam: Congrats!

September 22: The last results of Stephanie and Stefano on the photocatalytic Umpolung of enol ethers and enamides for the synthesis of amino alcohols have now appeared in Chemical Science (DOI: 10.1039/D0SC03655B).

September 18: LCSO Alumni Dr. Yifan Li has now started his independent career as assistant professor in ShanghaiTech University. Congrats Yifan!

September 2: Welcome to Vladyslav Smirnov, our new PhD student from Taras Shevchenko National University of Kyev.

September 1: Our collaborative work on photochemical functionalization of heterocycles with the Kokotos group started by Erikka during her visit supported by the COST CHAOS action with Marion has now appeared in Chemistry A European Journal ( DOI: 10.1002/chem.202002868).

August 26: A preprint of the last results of Luca, Mikus and Phill on catalytically formed chiral auxiliary for amino alcohol synthesis is now available at ChemRXiv ( DOI: 10.26434/chemrxiv.12855218.v1 ).

August 24: The five most interesting articles form the weekly LCSO journal club will be from now on posted on twitter!

August 7: Welcome to Dr. Nieves Ramirez-Hernandez our new postdoc from the Gonzalez Gomez group at the University of Alicante.

August 1: Official start of the NCCR Catalysis with Jerome as co-director.