Welcome to LCSO!

Synthesis of metal complexes, ligands, and organocatalysts. New catalytic reactions for C-C bond formation. Investigation of reactions mechanism. Synthesis of complex bioactive compounds.

Our group is driven by the passion of discovering new reactivity in organic chemistry, especially using catalysis. Basing on high energy molecules, such as strained rings or cyclic hypervalent iodine reagents for electrophilic alkynylation and other transformations, we develop non-conventional bond disconnections for the synthesis of important building blocks and bioactive molecules, as well as the modification of biomolecules . We also control the regioselective functionalization of alkenes and alkynes using in situ tethering approaches. Regular group meetings and seminars allow us to share and enhance our knowledge and love of organic chemistry.


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Latest News

June 18: The last work of Ming-Ming on the oxidative ring-opening of cyclopropylamides using photoredox catalysis is now just accepted in Angewandte Chemie (DOI: 10.1002/anie.202007864).

June 16: The last work of Nina on the Umpolung of enol ethers to access oxy-allyl cation equivalents with hypervalent iodine reagents is now just accepted in Angewandte Chemie (DOI: 10.1002/anie.202006707).

June 9: The preprint of the work of Stephanie and Stefano on the photocatalytic addition of EBX reagents onto enecarbamates and enol ethers is now available on ChemiRxiv (DOI: 10.26434/chemrxiv.12445577.v1).

May 29: The review of Vincent and Bastian on the catalytic enantioselective ring-opening of cyclopropanes is now just accepted in Chemical Reviews (DOI: 10.1021/acs.chemrev.0c00109).

May 29: The review of Stephanie, Marion and Luca on accessing reactive intermediates via organophotoredox catalysis is now just accepted in Beilstein Journal of Organic Chemistry (DOI: 10.3762/bjoc.16.103).

May 26: The last work of Eliott in collaboration with the Severin group on triazene substituted D-A cyclopropanes is now just accepted in Organic Letters (DOI: 10.1021/acs.orglett.0c01527).

May 20: Our work on the ethynylation of thiols in biomolecules has been highlighted in ChemistryViews.

May 20: Ming-Ming Wang has been awarded a Chemistry Travel Award of the Swiss Chemical Society. Congratulations!

May 1: The last work of Guillaume and Alec on the copper-catalyzed oxyvinylation of diazo compounds with VBX reagents is now just accepted in Organic Letters (DOI: 10.1021/acs.orglett.0c01150).

April 29: Phillip Greenwood successfully defended his PhD thesis. He is the fourteenth PhD student to obtain his degree at LCSO. Congratulations!

April 22: Second COVID bilateral online group meeting of LCSO, this time with the groups of Prof. Maurizio Prato at Trieste and San Sebastian.

April 1: The first bilateral online group meeting of LCSO with the Noel Group at TU Eindhoven has taken place.

April 1: The last work of Romain, Raj and Javier on ethynylation of cysteine is now accepted in Angewandte Chemie (DOI: 10.1002/anie.202002626). This was a highly successful collaboration with the Biofunctional Chemistry group at the University of Strasbourg and the Adibekian group at Scripps Florida.

March 31: The traditional LCSO Spring Group Photo this year unfortunately via Zoom due to COVID.

March 25: The first organic seminar online has taken place with Prof. Song Lin from Cornell University.

March 19: The last work of Guillaume and Alec on the three component reaction of alcohols, diazo compounds and EBX reagents is now accepted in Chemistry a European Journal (DOI: 10.1002/chem.202001317)!

March 16: Due to the expanding COVID-19 pandemics, LCSO labs are closed for an unknown time.

March 2: Congratulation to Dr. Franck Le Vaillant, former LCSO PhD, who has been selected to participate to the (Lindau Nobel Laureate meeting)!

February 7: Welcome to Dr. Emmanuelle Allouche our new postdoc joining from the (Charette group)!

January 22: Phill Greenwood has successfully passed his PhD exam: Congratulations!

January 13: Welcome to Dr. Abahya Mishra our new postdoc joining from the (Szpilman group)!

December 31: The last work of Julien and Guillaume on the copper-catalyzed oxyalkynylation of thiiranes is now accepted in Organic Letters (DOI: 10.1021/acs.orglett.9b04157)!

December 24: Our ultimate synthesis of TIPS-EBX with process and product safety studies performed by Merck has now been published in Organic Process Research and Development (DOI: 10.1021/acs.oprd.9b00498)!

December 19: Good bye party for Javier who is leaving the group after more than 2.5 years of postdoc: Good luck for your future outside LCSO.

December 16: The Swiss State has awarded 17 million Swiss Francs to the project suchcat (Sustainable Processes Through Catalysis) with Jerome as co-director!

December 13: The LCSO Christmas party has taken place at the Royal Savoy: 30 current and past LCSO members to celebrate also Jerome’s promotion to full professor.

December 13: Elija has successfully passed her first year candidacy exam. Congrat!

December 10: Raphael has received a teaching excellence award for his contribution to a new service course in organic chemistry. Congratulation!

December 4: Franck Le Vaillant has received the special “top 8%” distinction for his PhD thesis. Congratulation!