Welcome to LCSO!

Synthesis of metal complexes, ligands, and organocatalysts. New catalytic reactions for C-C bond formation. Investigation of reactions mechanism. Synthesis of complex bioactive compounds.

Our group is driven by the passion of discovering new reactivity in organic chemistry, especially using catalysis. Basing on high energy molecules, such as strained rings or cyclic hypervalent iodine reagents for electrophilic alkynylation and other transformations, we develop non-conventional bond disconnections for the synthesis of important building blocks and bioactive molecules, as well as the modification of biomolecules . We also control the regioselective functionalization of alkenes and alkynes using in situ tethering approaches. Regular group meetings and seminars allow us to share and enhance our knowledge and love of organic chemistry.



(Only complete applications following the guidelines will be considered!)

LCSO Synthesis Problems

LCSO on Twitter (Waser [email protected])

Latest News

December 6: The LCSO Christmas dinner has taken place a the restaurant Itoya.

November 24: Mingming has been awarded a top 8% distinction of EDCH for his PhD thesis. Congrats!

November 23: Eliott has passed his final PhD exam. Congrats!

November 21: The work of Stephanie and Franck on the fine-tuning of hypervalent iodine reagents in photoredox-catalyzed reactions and preliminary results for new transformations is now accepted in Helvetica Chimica Acta (DOI: 10.1002/hlca.202200161) in the Prof. Janine Cossy/Bürgenstock president issue.

November 6: The review of Ashis on Pd-Catalyzed functionalization of alkenes and alkynes using removable tethers is now accepted in Tetrahedron (DOI: 10.1016/j.tet.2022.133135).

November 4: Nina has passed her final PhD exam. Congrats!

October 24: The review of Raphael on azidation with hypervalent iodine reagents is now accepted in Synthesis (DOI: 10.1055/a-1966-4974).

October 12: Great day for LCSO, both the work of Nina on tyrosine functionalization and of Tin on cyclopropane alkynylation are now accepted in Chem. Sci. (DOI: 10.1039/D2SC04558C and DOI: 10.1039/D2SC04344K).

October 4: Our grant at the SNSF has been approved. Two new PhD positions will be open at LCSO in July 2023!

September 26: Tin has been selected to present his work in a short talk at the IASOC summer school. Congrats!

September 15: Helena Sole Avila come back to the group to start her PhD. Welcome!

September 8: Yuji and Diana were awarded a runner up prize for their posters at the SCS fall meeting. Congratulations!

September 6: The work of Eliott and Julien on the alkynylation of azadipeptides with EBXs is now accepted in Org. Lett. (DOI: 10.1021/acs.orglett.2c02625).

September 5: Emma successfully passed her first year candidacy exam. Congratulations!

September 2: The yearly LCSO Alumni meeting took place at BCH with a “gala cold buffet”.

September 1: Yuji successfully passed his first year candidacy exam. Congratulations!

August 22: André successfully defended his master thesis. Congratulations!

August 22: LCSO is now also on LinkedIn to share news about the group for people not active on twitter.

August 17: After two years “COVID break” the LCSO summer group outing could take place again: Hike and wine tasting in Lavaux.

August 8: The review of Mingming and Tin on the activation of aminocyclopropanes via radical intermediates is now accepted in Chem. Soc. Rev. (DOI: 10.1039/D2CS00090C).

July 29: Nieves was awarded a APOSTD 2022 postdoctoral fellowship from Generalitat Valenciana. Congratulations!

July 15: The work of Stefano on the enantioselective (4+3) annulation of cyclopropanes and azadienes for the synthesis of azepanones is now accepted in Angew. Chem., Int. Ed. (DOI: 10.1002/anie.202209006).

July 11: The work of Ashis, Thomas and Stefano on the first Pd-catalyzed aminoacetoxylation of alkenes using N,O-acetal tethers is now accepted in Org. Lett. (DOI: 10.1021/acs.orglett.2c01838).

July 1: Dylan Cleveland from Cambridge University joins the group for a Summer internship. Welcome!

July 1: Oleksandr Liashuk from Kyiv Taras Shevchenko National University joins the group as a visiting PhD student for one year. Welcome!

June 24: Ashis Das successfully defended his PhD thesis. He is the twenty-first PhD student to obtain their degree at LCSO. Congratulations!

June 13: The work of Ashis , Luca and Mikus on catalytically formed chiral auxiliaries via hydroalkoxylation is now accepted in ACS Catal. (DOI: 10.1021/acscatal.2c01809).

June 3: Stephanie Amos successfully defended her PhD thesis. She is the twentieth PhD student to obtain their degree at LCSO. Congratulations!