Author: Yimon Aye

2020 Esterbauer Memorial Award

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The lab is honored to be recognized by the International HNE Club‘s Hermann Esterbauer Award, in memory of Professor Hermann Esterbauer, an early pioneer in the biological studies of 4-hydroxynonenal (HNE) and related reactive metabolites.

2020 EFMC Award

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Our lab was recognized by the 2020 EFMC Award in Medicinal Chemistry – we are grateful for the prestigious recognition  

HuR you too!

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Invited contribution to a special issue in honor of Prof. Michael Graetzel’s 75th birthday, was made by Jesse et al. through the sequel of HuR. The mRNA‐Binding Protein HuR Is a Kinetically‐Privileged Electrophile Sensor Helvetica Wiley: Just Accepted 2020 April See here for our earlier publication on HuR by Jesse et al. We thank all (…)

The Ring Master is born

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Training of natural electrophiles to target a single protein leads to improved target specificity and drug activity, but retains the electrophile’s privileged properties. The first step to translation of T-REX, by Xuyu et al., is set to appear in ACS Central Science: Precision targeting of pten-null triple-negative breast tumors guided by electrophilic metabolite sensing We (…)

2020 ACS Award in Biological Chemistry

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We thank the American Chemical Society (ACS) and the award sponsor, Eli Lilly & Co., for recognizing our lab with the prestigious ACS Eli Lilly Award. Previous awardees since 1935