Publications

68 Publications since 2013

• From the American Chemical Society Journals: Accounts of Chemical Research (2021); ACS Central Science (2018, 2020); Journal of the American Chemical Society [2013, 2015 (×2), 2016, 2019]; ACS Chemical Biology (2016, 2017, 2018, 2020, 2022 (x2); Chemical Reviews (2018); Biochemistry [2013, 2017 (×2)]; Chemical Research in Toxicology (2016, 2022)
• From the Nature Publishing Group: Nature Chemical Biology (2017, 2018); Nature Protocols [2016, 2023]; Oncogene (2015); Nature Communications (2021); Springer Nature (2022); Nature Synthesis (2024)
• From the Cell Press & Elsevier: Cell (2024); Cell Chemical Biology [2017 (×2), 2018, 2019, 2023]; Trends in Biochemical Sciences [2018 (×2), 2019]; Trends in Genetics (2024); Current Opinion in Chemical Biology [2019 (x2)]; Methods in Enzymology (2019); Biorganic & Medicinal Chemistry Letters (2022); Bioorganic & Medicinal Chemistry (2024)
• From the National Academy of Sciences: PNAS (2022)
• From the eLife Sciences Publications Ltd.: eLife (2022)
• From the Royal Society of Chemistry Journals: RSC Chemical Biology  (2020, 2022); Chemical Society Reviews (2021); RSC Medicinal Chemistry (2021)
• From Wiley: ChemBioChem-European Journal of Chemical Biology (2014, 2019, 2021, 2024); Current Protocols in Chemical Biology (2018); BioEssays (2018); Helvetica chimica acta [2020, 2023 (x2)]; ChemMedChem (2021)
• From Frontiers (Switzerland): Frontiers Chemistry (2019); Frontiers Neuroscience (2020)
• From the Federation of American Societies for Experimental Biology (FASEB): FASEB Journal (2019)
• From the Swiss Chemical Society: Chimia (2020, 2022)
• From the Mary Ann Liebert Inc. publishers: Antioxidants & Redox Signaling (2019)

---

• Metaphiles: A New Concept that Illuminates Structure-Function Basis of Electrophile Sensing & Signaling

  2024 – In revision (original research)

  Chloe Rogg^#, Kuan-Ting Huang^#, et al., and Yimon Aye

  ---

• Organ-Specific Responsivity Mapping Unmasks Partitioning between Localized Metabolite Production Governing Global Lipid Storage & Enzyme Inhibition

  July 2024 – Cell – accepted in principle (original research)

  Jinmin Liu^#, Amogh Kulkarni, Yong-Qi Gao, Daniel A. Urul, Romain Hamelin, Marcus J. C. Long, and Yimon Aye

  ---

• Let’s Get Biophysical – How to Get your Favorite Protein’s Digits

  2024 – accepted (perspective) – Bioorganic & Medicinal Chemistry – invited contribution

  Marcus J. C. Long and Yimon Aye

  ---

• Atavistic Electrophile Sensing that Confers Animal Fitness Advantage through Selective Amino-Acid Detoxification

  2024 – In revision (original research)

  Daniel A. Urul^#, Yong-Qi Gao^#, Jinmin Liu^#, et al., and Yimon Aye

  ---

• NCBP1 Electrophilic-Stress Signaling in the Nucleus Promotes Alternatively-Spliced S6K1 that Dominantly Inhibits Global Translation

  2024 – In revision (original research) – available on BioRxiv

  Dalu Chang^#, et al., and Yimon Aye

  ---

• Precision Immuno-Chemical Biology: toward Decoding Spatiotemporal Signaling Activities of Reactive Immunometabolites

  2024 – accepted (Perspective) – Communications Chemistry – invited contribution – available on Preprints

  Kuan-Ting Huang^# and Yimon Aye

• ---

  Horner–Wadsworth–Emmons olefination for bioconjugation

  June 2024 – Nature Synthesis (News & Views) – invited contribution

  Yimon Aye

• ---

  Formaldehyde Regulates One-Carbon Metabolism and Epigenetics

  March 2024 – Trends in Genetics (Spotlight) – invited contribution

  Marcus J. C. Long^# and Yimon Aye

• ---

  Climbing into their Skin to Understand Contextual Protein-Protein Associations and Localizations: Functional Investigations in Transgenic Live Model Organisms

  February 2024 – ChemBioChem (perspective) – invited contribution to EFMC Collections

  

Marcus J. C. Long^# and Yimon Aye

---

• Tag, you’re it! G-ICAT Identifies p-120 Cysteine Glutathionylation Triggering E-Cadherin Destabilization

  December 2023 – Cell Chemical Biology (preview) – invited contribution

  

  Kevin T. Fridianto^# and Yimon Aye

  ---

• Keap It in the Family: How to Fish out New Paradigms in Keap1-Mediated Cell Signaling

  November 2023 – Helvetica Wiley (perspective) – invited contribution to Special Issue in honor of Professor Scott E. Denmark

  

  Marcus J. C. Long^#, Kuan-Ting Huang, and Yimon Aye

• ---

  Z-REX: Shepherding Reactive Electrophiles to Specific Proteins Expressed either Tissue-Specifically or Ubiquitously, and Recording the Resultant Functional Electrophile-Induced Redox Responses in Larval Fish

April 2023 – Nature Protocols (selected as “This week’s Featured Protocol” by the journal)

Kuan-Ting Huang^#, Jesse R. Poganik^#, Saba Parvez, Sruthi Raja, Brian Miller, Marcus J. C. Long, Joseph R. Fetcho, and Yimon Aye

---

• Monitoring On-Target Signaling Responses in Larval Zebrafish – Z-REX Unmasks Precise Mechanisms of Electrophilic Drugs and Metabolites

  March 2023 – JoVE – (invited contribution)

Kuan-Ting Huang^#, Phillippe Ly^#, Jesse R. Poganik, Saba Parvez, Marcus J. C. Long, Yimon Aye

---

• Structural Insights into Electrophiles and Electrophilic Metabolites Sensing and Signaling: The Missing Information 

  February 2023 – Helvetica (Wiley) – (invited perspective for the special issue: Helvetica & Swiss Women in Chemistry)(In Press)

Chloé Rogg^# and Yimon Aye

---

• Finding a vocation for validation: Taking proteomics beyond association and location

  December 2022 – RSC Chemical Biology – (invited perspective: electrophile signaling program)

Marcus J. C. Long^#, Jinmin Liu, and Yimon Aye*

(^#first author, *corresponding author)

---

• Still no Rest for the Reductases: RNR Structure & Function – an update

  November 2022 – Invited contribution to Springer Book Series – Subcellular Biochemistry: Macromolecular Protein Complexes IV

  

  Marcus J. C. Long^#, Phillippe Ly, and Yimon Aye

  ---

• Z-REX uncovers a bifurcation in function of Keap1 paralogs

  October 2022 – eLife – (original research: electrophile signaling program)

Alexandra Van-Hall Beauvais^#, Jesse R. Poganik^#, Kuan-Ting Huang^#, Saba Parvez, Yi Zhao, Hong-Yu Lin, Xuyu Liu, Marcus J. C. Long*, and Yimon Aye*

(^#co-first authors, *co-corresponding authors)

---

Sept 2021 – RSC Medicinal Chemistry – invited review (electrophile signaling program)

Marcus J. C. Long*, Phillippe Ly, and Yimon Aye*

(^#first author, *co-corresponding author)

---

• The not-so-identical twins: (Dis)similarities between reactive electrophile and oxidant sensing & signaling

Aug 2021 – RSC Chemical Society Reviews – invited review (electrophile signaling program)

Marcus J. C. Long^#, Kuan-Ting (Tim) Huang, and Yimon Aye*

(^#first author, *corresponding author)

---

• Science’s response to CoVID-19

April 2021 – ChemMedChem

(contribution as part of the 2020 EFMC award)

Marcus J. C. Long^# and Yimon Aye*

(^#first author, *corresponding author)

---

• Can Precision Electrophile Signaling Make a Meaningful and Lasting Impression in Drug Design?

April 2021 – ChemBioChem

Marcus J. C. Long, Amogh Kulkarni and Yimon Aye

---

• An oculus to profile and probe target engagement in vivo: How T-REX was born and its evolution into G-REX

 
Selected for Cover Art of Feb 2021 issue:

Nov 2020 – Accounts of Chemical Research

(electrophile signaling program: invited accounts)

Marcus J. C. Long^#, Chloe Rogg, and Yimon Aye*

(^#first author, *corresponding author)

---

• Where Electrophile Signaling and Covalent Ligand-Target Mining Converge

Sep 2020 – Chimia

Author: Yimon Aye

---

• Contribution to Voices of Chemical Biology

May 2020 – Nature Chemical Biology

Author: Yimon Aye

---

• Precision targeting of pten-null triple-negative breast tumors guided by electrophilic metabolite sensing

May 2020 – ACS Central Science

(electrophile signaling program: original research)

Xuyu Liu^#, Marcus J. C. Long, Benjamin Hopkins, Chaosheng Luo, Lingxi Wang, and Yimon Aye*

(^#first author, *corresponding author)

---

• Neighborhood watch: tools for defining locale-dependent subproteomes and their contextual signaling activities

May 2020 – RSC Chemical Biology

(electrophile signaling program: perspective)

Marcus J. C. Long^#, Yi Zhao, and Yimon Aye*

(^#first author, *corresponding author)

---

• Empowering global chemical biology at the dawn of the new decade

April 2020 – contribution to NCCR Chemical Biology (UNIGE/EPFL)

ACS Chemical Biology (symposium report)

Sascha Hoogendoorn* and Yimon Aye*

(*co-corresponding authors)

---

• The mRNA-binding protein HuR is a kinetically-privileged electrophile sensor

April 2020 – invited contribution to special issue dedicated to Professor Michael Graetzel

Helvetica Chimica Acta (Wiley)

(electrophile signaling program: original research)

Jesse R. Poganik^#, Alexandra K. Van Hall-Beauvais^#, Marcus J. C. Long, Michael T. Disare, Yi Zhao, and Yimon Aye*

(^#co-first authors, *corresponding author)

---

• Electrophile signaling and emerging immuno- and neuro-modulatory electrophilic pharmaceuticals

February 2020– invited contribution to special issue:

‘Molecular mechanisms of thiol-based redox homeostasis and signaling in the brain’

Frontiers Neuroscience

(electrophile signaling program: review article)

Jesse R. Poganik^#,, and Yimon Aye*

(^#first author, *corresponding author)

---

• Clofarabine commandeers the RNR-α-ZRANB3 nuclear signaling axis

January 2020– Cell Chemical Biology

(nucleotide signaling program: original research)

Marcus J. C. Long^#, Yi Zhao^#, and Yimon Aye*

(^#co-first authors, *corresponding author)

---

• Post-transcriptional regulation of Nrf2-mRNA by the mRNA-binding proteins HuR and AUF1

September 2019– FASEB Journal

(electrophile signaling program: original research)

Jesse R. Poganik^#, Marcus J. C. Long, Michael T. Disare, Xuyu Liu, Sung-Hee Chang, Timothy Hla, and Yimon Aye*

(^#first author, *corresponding author)

---

---

• Getting the right grip? How understanding electrophile selectivity profiles could illuminate our understanding of redox signaling

September 2019– Antioxidants & Redox Signaling

(electrophile signaling program: invited review)

Marcus J. C. Long^#, Lingxi Wang, and Yimon Aye*

(^#first author, *corresponding author)

---

• Interrogating precision electrophile signaling

February 2019 – Trends in Biochemical Sciences (technology of the month)

(electrophile signaling program)

Jesse R. Poganik^#, Marcus J. C. Long, and Yimon Aye*

(^#first author, *corresponding author)

---

• Genie in a bottle: Controlled release help tame natural polypharmacology

February 2019 – Current Opinion in Chemical Biology (Chemical Genetics opinion piece)

(electrophile signaling program)

Xuyu Liu^#, Marcus J. C. Long^#, and Yimon Aye*

(^#co-first authors, *corresponding author)

---

---

• Modular total synthesis and cell-based anticancer activity evaluation of ouabagenin and other cardiotonic steroids with varying degrees of oxygenation

February 2019 – Journal of the American Chemical Society (Collaboration with the Nargony Lab)

Just accepted

• Breaking the fourth wall: Modulating quaternary associations for protein regulation and drug discovery

February 2019 – ChemBioChem (invited contribution to ChemBioTalents special issue)

(Review integrating both electrophile and nucleotide signaling programs)

Marcus J. C. Long^#, Dziyana Hnedzko^§, Bo Kyoung Kim^§, and Yimon Aye^*

(^#first author, ^§joint second-author, ^*corresponding author)

---

• Chemical biology gateways to mapping location, association, and pathway responsivity

February 2019 – nominated contribution to the Rising Stars in Chemistry Frontiers Special Issue (Perspective)

Xuyu Liu#, Marcus J. C. Long#, and Yimon Aye*

(#, co-first authors. *, corresponding author)

---

• Weighing up the selenocysteome uncovers new sec-rets

October 2018 – Cell Chemical Biology (Preview)

Jesse R. Poganik#, and Yimon Aye*

(#, first author *, corresponding author)

---

• Proteomics and Beyond: Cell decision making shaped by reactive electrophiles

Xuyu Liu#, Marcus J. C. Long#, and Yimon Aye*

(#, co-first authors. *, corresponding author)

September 2018 – Trends in Biochemical Sciences (Review) (electrophile signaling program)

---

• Nuclear RNR-α Antagonizes Cell Proliferation by Directly Inhibiting ZRANB3

Yuan Fu#, Marcus J. C. Long#, Somsinee Wisitpitthaya, Huma Inayat, Timothy M. Pierpont, Islam M. Elsaid, Jordana C. Bloom, Joaquin Ortega, Robert S. Weiss, and Yimon Aye*

(#, co-first authors. *, corresponding author)

August 2018 – Nature Chemical Biology (Original Research) (nucleotide signaling program)

---

• Redox Signaling by Reactive Electrophiles and Oxidants

Saba Parvez#, Marcus J. C. Long#, Jesse R. Poganik, and Yimon Aye*

(#, co-first authors. *, corresponding author)

August 2018 – Chemical Reviews (Review Article) (electrophile signaling program)

---

• Cardiovascular small heat shock protein HSPB7 is a kinetically-privileged reactive electrophilic species (RES) sensor

Sanjna L. Surya#, Marcus J. C. Long#, Daniel A. Urul, Yi Zhao, Emily J. Mercer, Islam M. Elsaid, Todd Evans, and Yimon Aye*  (#, co-first authors. *, corresponding author)

February 2018 – ACS Chemical Biology (Original Research) (electrophile signaling program) Invited contribution to the 2018 “Biosensors” Special Issue of ACS Chemical Biology

---

• Single-protein-specific redox targeting in live mammalian cells and C. elegans

Alexandra Van Hall-Beauvais#, Yi Zhao, Daniel A. Urul, Marcus J. C. Long, and Yimon Aye*

(#, first author. *, corresponding author)

DOI: 10.1002/cpch.43

February 2018 – Current Protocols in Chemical Biology (Wiley) (Protocols) (electrophile signaling program in cultured cells and C. elegans)

---

• Ube2V2 is a Rosetta Stone bridging redox and ubiquitin codes, coordinating DNA damage responses

• Yi Zhao#, Marcus J. C. Long, Yiran Wang, Sheng Zhang, and Yimon Aye* (#, first author. *, corresponding author)

Highlight in Cornell Chronicle

February 2018 – ACS Central Science (Original Research) (electrophile signaling program in cultured cells and in zebrafish)

---

• Getting the message? Native reactive electrophiles pass two out of three thresholds to be bona fide signaling mediators

Jesse R. Poganik#, Marcus J. C. Long#, and Yimon Aye*

(#, co-first authors. *, corresponding author)

February 2018 – BioEssays (Wiley) (Problems & Paradigms) (electrophile signaling program)

---

• Precision electrophile tagging in C. elegans

	Selected as an “ACS Editors’ Choice” communication!
	Click Here For LiveSlides Of The Paper

Marcus J. C. Long#, Daniel A. Urul#, Shivansh Chawla#, Hong-Yu Lin+, Yi Zhao+, Joseph A. Haegele, Yiran Wang, and Yimon Aye*

(#, co-first authors. +, co-second authors. *, corresponding author)

Invited contribution to “Future of Biochemistry” Special Issue of ACS Biochemistry (scheduled for January 2018)

September 2017 – Original Research Communication

---

• β-TrCP1 is a vacillatory regulator of Wnt signaling

Marcus J. C. Long#, Hong-Yu Lin#, Saba Parvez, Yi Zhao, Jesse R. Poganik, Paul Huang, and Yimon Aye*

(#, co-first authors. *, corresponding author)

 Highlighted in Cornell Chronicle: Group discovers avenue for precision cancer treatment

July 22 2017 – Cell Chemical Biology (Original research) (electrophile signaling program)

---

• Quo vadis: The boundless trajectories of chemical biology

Jeremy M. Baskin*, and Yimon Aye*

(*, co-corresponding authors)

May 24 2017 –  Symposium report contribution

---

• Privileged electrophile sensors: a resource for covalent drug development

Marcus J. C. Long#, and Yimon Aye*

(#, first author. *, corresponding author)

May 24 2017 – Cell Chemical Biology (Perspective) (electrophile signaling program in cells and fish)

---

• Akt3 is a privileged first responder in isozyme-specific electrophile response

2017 13(3):333-338

Marcus J. C. Long#, Saba Parvez#, Yi Zhao, Sanjna L. Surya, Yiran Wang, Sheng Zhang, and Yimon Aye*

(#, co-first authors. *, corresponding author)

Highlighted in Nature Chemical Biology “News & Views”    2017 13(3):244-245

Highlighted in Cornell Chronicle: Group uses its own ‘toolset’ to probe chemical responses

March 2017 – Nature Chemical Biology (Original Research) (electrophile signaling program in cultured cells and in zebrafish)

---

• Subcellular Redox Targeting: Bridging In Vitro and In Vivo Chemical Biology

Marcus J. C. Long#, Jesse R. Poganik§, Souradyuti Ghosh§, and Yimon Aye*

(#, first author. §, shared second-author. *, corresponding author)

January 2017 – ACS Chemical Biology (Review Article) DOI: 10.1021/acschembio.6b01148

---

• T-REX on-demand redox targeting in live cells

Saba Parvez#, Marcus J. C. Long#,  Hong-Yu Lin†, Yi Zhao†, Joseph A. Haegele, Vanha N. Pham, Dustin K. Lee, and Yimon Aye*

(#, co-first authors. †, co-second authors. *, corresponding author)

Nature Protocols 201611 2328-2356

December 2016 – Nature Protocols (electrophile signaling program)

---

• The Die is Cast: Precision electrophilic modifications contribute to cellular decision making

Selected as an “ACS Editors’ Choice” communication!

– peer-reviewed article contributed as part of 2016 ACS CRT young investigator award to Aye Lab

Marcus J. C. Long#, and Yimon Aye*   (#, first author. *, corresponding author)

September 2016 – ACS Chem Res Toxicol (Perspective)- (electrophile signaling program)

AlsoSelected for the Journal Cover Art !

---

• Cladribine and fludarabine nucleotides induce distinct hexamers defining a common mode of reversible RNR inhibition

ACS Chemical Biology (research article) 2016 11 2021-2032

Somsinee Wisitpitthaya#, Yi Zhao, Marcus J. C. Long, Minxing Li, Elaine A. Fletcher, William A. Blessing, Robert S. Weiss, and Yimon Aye*

(#, first author.*, corresponding author)

May 2016 – ACS Chem Bio (Original Research) (nucleotide signaling program)

---

• On-demand targeting: Investigating biology with proximity-directed chemistry

Click Here For ACS LiveSlides on the journal website

---

• Selected as a Spotlights article on recent JACS publications!

“Chemical Biology On Demand and In High-Definition”

Journal of the American Chemical Society (Spotlights) 2016 138 4269-4269

Journal of the American Chemical Society (Perspective) 2016 138 3610-22

Marcus J. C. Long#,  Jesse R. Poganik, and Yimon Aye*

(#, first author. *, corresponding author)

Feb 2016 – J Am Chem Soc (Perspective) ACS OPEN ACCESS ARTICLE (electrophile signaling program)

---

• A generalizable platform for interrogating target- and signal-specific consequences of  electrophilic modifications in redox-dependent cell signaling.

Journal of the American Chemical Society (research article) 2015 137 6232-44

Hong-Yu Lin#, Joseph A. Haegele, Michael T. Disare, Qishan Lin, and Yimon Aye*

(#, first author. *, corresponding author)

Apr 2015 – J Am Chem Soc (Original Research) (electrophile signaling program)

---

• Substoichiometric hydroxynonenylation of a single protein recapitulates whole-cell-stimulated antioxidant response

Journal of the American Chemical Society (research communication) 2015 137 10-3

Saba Parvez#, Yuan Fu#, Jiayang Li, Marcus J. C. Long, Hong-Yu Lin, Dustin K. Lee, Gene S. Hu, and Yimon Aye*

(#, co-first authors. *, corresponding author)

Jan 2015 – J Am Chem Soc (Original Research) (electrophile signaling program)

---

• Ribonucleotide reductase and cancer: biological mechanisms and targeted therapies

Oncogene(mini review)  2015  34 2011–2021 Yimon Aye*, Minxing Li#, Marcus J. C. Long and Robert S. Weiss* (#, first author. *, co-corresponding authors)

Apr 2015 – Oncogene Mini Review (nucleotide signaling program)

---

• A fluorimetric readout reporting the kinetics of nucleotide-induced human ribonucleotide reductase oligomerization

ChemBioChem (research article) 2014 15  2598-604

Yuan Fu, Hong-Yu Lin#, Somsinee (Sine) Wisitpitthaya#, William A. Blessing, and Yimon Aye*

(#, co-2nd authors. *, corresponding author)

Aug 2014 – ChemBioChem (Original Research) (nucleotide signaling program)

---

• Uncoupling of allosteric and oligomeric regulation in a functional hybrid enzyme constructed from Escherichia coli and human ribonucleotide reductase

Biochemistry (research article) 2013 52 7050-9

Yuan Fu#, Marcus J. C. Long, Mike Rigney, Saba Parvez, William A. Blessing, and Yimon Aye*

(#, first author. *, corresponding author)

Sept 2013 – Biochemistry (Original Research)(nucleotide signaling program)

---

• Temporally controlled targeting of 4-hydroxynonenal to specific proteins in living cells

Journal of the American Chemical Society (research communication) 2013 135 14496-9

Xinqiang Fang#, Yuan Fu#, Marcus J. C. Long, Joseph A. Haegele, Eva J. Ge, Saba Parvez, and Yimon Aye*

(#, co-first authors. *, corresponding author)

Sept 2013 – J Am Chem Soc (Original Research) (electrophile signaling program)

---

PUBLICATIONS DURING TRAINING From postdoctoral research (MIT, USA): 08/2009 — 06/2012

Original research:

Clofarabine 5´-Di and –Triphosphates Inhibit Human Ribonucleotide Reductase by Altering the Quaternary Structure of its Large Subunit” Yimon Aye and JoAnne Stubbe*; Proceedings to the National Academy of Sciences USA (Direct Submission) 2011, 108, 9815.

Clofarabine Targets the Large Subunit (α) of Human Ribonucleotide Reductase in Live Cells by Assembly into Persistent Hexamers” Yimon Aye, Edward J. Brignole, Marcus J. C. Long, Johnathan Chitturulu, Catherine L. Drennan, Francisco J. Asturias, and JoAnne Stubbe*; Chemistry and Biology 2012, 19, 799.

Mechanistic Studies of Semicarbazone Triapine Targeting Ribonucleotide Reductase in Vitro and in Mammalian Cells: Tyrosyl Radical Quenching Not Involving Reactive Oxygen Species” Yimon Aye, Marcus J. C. Long and JoAnne Stubbe*; Journal of Biological Chemistry 2012, 287, 35768.

“3.3-Å resolution cryo-EM structure of human ribonucleotide reductase with substrate and allosteric regulators bound” Edward J. Brignole, Kuang-Lei Tsai, Johnathan Chittuluru, Haoran Li, Yimon Aye, Pawel A Penczek, JoAnne Stubbe*, Catherine L. Drennan*, Francisco Asturias*; eLife 2018;7:e31502 doi: 10.7554/eLife.31502

From PhD thesis research (Harvard University, USA):

07/2004 — 05/2009

Independent review article:

“Vinyl-, Propargyl- and Allenylsilicon Reagents in Asymmetric Synthesis: Relatively Untapped Resource of Environmentally-Benign Reagents” Marcus J. Curtis-¬Long and Yimon Aye*; Chemistry, A European Journal 2009, 15, 5402.

Original research:

“Structural Report for Sc[(R,R)-norephedrine-pybox](OTf)3 Dimeric Complex” Richard J. Staples* and Yimon Aye; Journal of Chemical Crystallography 2008, 38, 49.

“Aluminum-catalyzed Enantio- and Diastereoselective Carbonyl Addition of Propargylsilanes. A New Approach to Enantioenriched Vinyl Epoxides” David A. Evans* and Yimon Aye; Journal of the American Chemical Society 2007, 129, 9606.

“Enantioselective Scandium-catalyzed Vinylsilane Additions: A New Approach to the Synthesis of β,γ-Unsaturated α-Amino Acid Derivatives” David A. Evans* and Yimon Aye; Journal of the American Chemical Society 2006, 128, 11034.

“Asymmetric, Anti–selective Scandium-catalyzed Sakurai Additions to Glyoxamide. Applications to the Syntheses of N-Boc- D-Alloisoleucine and D-Isoleucine” David A. Evans*, Yimon Aye and Jimmy Wu; Organic Letters 2006, 8, 2071.

From undergraduate master’s thesis research (Oxford University, UK):

10/2003 — 05/2004

“Parallel kinetic resolution of tert-butyl (RS)-3-oxy-substituted cyclopent-1-ene-carboxylates for the asymmetric synthesis of 3-oxy-substituted cispentacin and transpentacin derivatives” Yimon Aye, Stephen G. Davies,* A. Christopher Garner, Paul M. Roberts, Andrew D. Smith and James E. Thomson; Organic and Biomolecular Chemistry, 2018, 6, 2195.

From undergraduate summer research (MIT, USA):

Summer 2003

“Copper-catalyzed Asymmetric Conjugate Reduction as a Route to Novel β-Azaheterocyclic Acid Derivatives” Matthew P. Rainka, Yimon Aye and Stephen L. Buchwald*; Proceedings to the National Academy of Sciences USA, 2004, 101, 5821.