Minority governance!

News & announcements

By engineering and applying function-guided proximity-mapping approach, Localis-REX, we have uncovered (Zhao, Miranda, et al., PNAS) that even small fractions of endogenous proteins existing outside their canonical locale can show significantly-elevated electrophilic-metabolite sensing against the protein in its canonical locale. This minority of electrophile-sensing proteins can strongly influence activity of the bulk protein and hence (…)

2021 International Chemical Biology Society Global Lectureship Award

News & announcements

We are most grateful to be recognized by this prestigious international honor. We thank the International Chemical Biology Society (ICBS).

Catch of the day!

News & announcements

Our latest work leveraging T-REX and zebrafish immune models has helped to uncover the precise mode-of-mechanism of pleiotropic electrophilic drugs (Poganik, Huang et al Nature Communications). We thank all of the contributing team members and funders supporting this study. “A tool to interrogate a new class of drugs” by EPFL-SB news

2022 Tetrahedron Young Investigator Award

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We are hugely humbled to receive the 2022 TYI Award in Bioorganic & Medicinal Chemistry and grateful for the honor.

Pierre scooped the 2021 NCCR Best Thesis Prize!

News & announcements

Hearty congratulations to Pierre on earning this highly-coveted prize among many talented and dedicated chemical biology master students of the 2021 graduating class.