Author: Yimon Aye

Raise your glasses!

News & announcements

Our idea to launch a brand-new collaborative research direction involving precision chemical-biology & bioengineering tools development and applications, was approved for a SPIRIT grant. We are most grateful for the support from the Swiss National Science Foundation.

2020 Esterbauer Memorial Award

News & announcements

The lab is honored to be recognized by the International HNE Club‘s Hermann Esterbauer Award, in memory of Professor Hermann Esterbauer, an early pioneer in the biological studies of 4-hydroxynonenal (HNE) and related reactive metabolites.

2020 EFMC Award

News & announcements

Our lab was recognized by the 2020 EFMC Award in Medicinal Chemistry – we are grateful for the prestigious recognition  

HuR you too!

News & announcements

Invited contribution to a special issue in honor of Prof. Michael Graetzel’s 75th birthday, was made by Jesse et al. through the sequel of HuR. The mRNA‐Binding Protein HuR Is a Kinetically‐Privileged Electrophile Sensor Helvetica Wiley: Just Accepted 2020 April See here for our earlier publication on HuR by Jesse et al. We thank all (…)

The Ring Master is born

News & announcements

Training of natural electrophiles to target a single protein leads to improved target specificity and drug activity, but retains the electrophile’s privileged properties. The first step to translation of T-REX, by Xuyu et al., is set to appear in ACS Central Science: Precision targeting of pten-null triple-negative breast tumors guided by electrophilic metabolite sensing We (…)