Author: Yimon Aye
Raise your glasses!
Our idea to launch a brand-new collaborative research direction involving precision chemical-biology & bioengineering tools development and applications, was approved for a SPIRIT grant. We are most grateful for the support from the Swiss National Science Foundation.
2020 Esterbauer Memorial Award
The lab is honored to be recognized by the International HNE Club‘s Hermann Esterbauer Award, in memory of Professor Hermann Esterbauer, an early pioneer in the biological studies of 4-hydroxynonenal (HNE) and related reactive metabolites.
2020 EFMC Award
Our lab was recognized by the 2020 EFMC Award in Medicinal Chemistry – we are grateful for the prestigious recognition
HuR you too!
Invited contribution to a special issue in honor of Prof. Michael Graetzel’s 75th birthday, was made by Jesse et al. through the sequel of HuR. The mRNA‐Binding Protein HuR Is a Kinetically‐Privileged Electrophile Sensor Helvetica Wiley: Just Accepted 2020 April See here for our earlier publication on HuR by Jesse et al. We thank all (…)
The Ring Master is born
Training of natural electrophiles to target a single protein leads to improved target specificity and drug activity, but retains the electrophile’s privileged properties. The first step to translation of T-REX, by Xuyu et al., is set to appear in ACS Central Science: Precision targeting of pten-null triple-negative breast tumors guided by electrophilic metabolite sensing We (…)