Basic and Translational Cancer Research

EPFL research groups

Cathrin Brisken

Breast cancer, mouse genetic, mammary gland development, mouse models, patient derived xenografts, estrogen and progesterone, endocrine disruptors

Michele De Palma

Tumor-associated macrophages, tumor angiogenesis and antiangiogenic therapy Immunotherapy, microRNAs, exosomes and extracellular vesicles, mouse models of cancer, immune cell engineering, lentiviral vector technologies

Douglas Hanahan

Cancer, translational oncology, genetically engineered mouse models of human cancer, tumor microenvironment, angiogenesis, invasion, metastasis, pre-clinical trials

Joerg Huelsken

Tumor heterogeneity and stemness in cancer

Freddy Radtke

Notch, stem and progenitor cells, self-renewing tissues, differentiation, cancer, genetic mouse models

Elisa Oricchio

Cancer genetic, mouse models, therapy, stem cells, lymphoma

Wouter Karthaus

Endocrine cancers, endocrine therapy resistance, stem cell biology, organoid technology

Sebastian Waszak

Computational neuro-oncology, biomedical data science, clinical cancer genomics, diffuse midline glioma, diffuse intrinsic pontine glioma, medulloblastoma, genetic tumour syndromes

Nicolas Thomä – Paternot Chair

Chemical biology, structural Biology, gene expression, oncogenic fusion proteins DNA-bound macromolecular machines, molecular glues, expanding the druggable space in cancer

Affiliated research groups

Giovanni Ciriello

Cancer genomics & evolution, cell plasticity, chromatin 3D architecture, computational biology

Christoph Merten

Microfluidic technology develpment, single cell analysis, antibody discovery, personalized cancer therapy

Andrea Ablasser

DNA sensing, inflammation, antitumor immunity, cGAS-STING pathway

George Coukos

Tumor immunology, T-cell therapies, cancer vaccines, bioinformatics and engineering, clinical trials

Tatiana Petrova

Transcription, differentiation, cancer stem cells, intestinal and vascular development, lymphedema, cancer