Deep dive into huntingtin inclusions:
et al. “Nuclear and cytoplasmic huntingtin inclusions exhibit distinct biochemical composition, interactome and ultrastructural properties” BioRxiv (2020)Â doi: https://doi.org/10.1073/pnas.1913904117
Reconstructing Lewy body formation offers insight into pathology formation and neurodegeneration in Parkinsonâs disease:
Anne-Laure Mahul-Mellier et al. “The process of Lewy body formation, rather than simply α-synuclein fibrillization, is one of the major drivers of neurodegeneration.” PNAS (2020) doi: https://doi.org/10.1073/pnas.1913904117
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A new perspective on the role of phosphorylation in Alzheimerâs and other tau pathologies:
Haj-Yahya et al. “SiteâSpecific Hyperphosphorylation Inhibits, Rather than Promotes, Tau Fibrillization, Seeding Capacity, and Its Microtubule Binding.” Angewandte Chemie (2019). doi: https://doi.org/10.1002/anie.201913001