Home of REX technologies: T-REX™ delivery and G-REX™ profiling – Electrophile signaling and stress response – Nucleotide signaling and genome maintenance
NEWS & ANNOUNCEMENTS
A SPARK of inspiration gave us the chance to JUMP forward
We thank the Swiss National Science Foundation (SNSF)’s pilot funding scheme SPARK, that is designed to promote unconventional projects and uses a new double-blind reviewing process, for supporting our proposed idea, JUMP, among >700 submissions.
The role of the ZRANB3/RNR signaling axis in cancer comes into focus
Our new paper detailing how ZRANB3 is a poignant example of non-oncogene addiction in H-RasG12V-induced transformation and how nuclear RNR-alpha can inhibit this function is set to appear in Cell Chemical Biology. Critically, some approved anti-cancer drugs targeting RNR-alpha such as clofarabine also taps into this pathway:Clofarabine commandeers the RNR-α—ZRANB3 nuclear signaling axisWe thank our (…)
2020 ACS Award in Biological Chemistry
We thank the American Chemical Society (ACS) and the award sponsor, Eli Lilly & Co., for recognizing our lab with the prestigious ACS Eli Lilly Award.Previous awardees since 1935