Electronic readout of DNA amplification in nanoliter chambers. Strategies towards highly parallel semiconductor-based nucleic acid amplification testing.

S. Tomar / C. Guiducci (Dir.)  

Lausanne, EPFL, 2023. 

Prediction of Dispersion Rate of Airborne Nanoparticles in a Gas-Liquid Dual-Microchannel Separated by a Porous Membrane: A Numerical Study

Z. Sheidaei; P. Akbarzadeh; C. Guiducci; N. Kashaninejad 

Micromachines. 2022-12-01. Vol. 13, num. 12, p. 2220. DOI : 10.3390/mi13122220.

Microfluidic systems for in-flow bioanalytes collection

P-E. M. Thiriet / C. Guiducci (Dir.)  

Lausanne, EPFL, 2022. 

Recombinase polymerase amplification in minimally buffered conditions

S. Tomar; B. Lavickova; C. Guiducci 

Biosensors and Bioelectronics. 2021-11-15. Vol. 198, p. 113802. DOI : 10.1016/j.bios.2021.113802.

Integration of Ultra-Low Volume Pneumatic Microfluidics with a Three-Dimensional Electrode Network for On-Chip Biochemical Sensing

S. Tomar; C. Lasne; S. Barraud; T. Ernst; C. Guiducci 

Micromachines. 2021-06-28. Vol. 12, num. 7, p. 762. DOI : 10.3390/mi12070762.

Device and method for pre-term birth risk assessment

E. Garcia Cordero; C. Guiducci; D. Baud; G. Porro; L. Kasem 

US2022296221; EP4031004; MX2022003307; CA3150506; WO2021053649.


Rapid Multianalyte Microfluidic Homogeneous Immunoassay on Electrokinetically Driven Beads

P-E. M. Thiriet; D. I. Medagoda; G. Porro; C. Guiducci 

Biosensors. 2020-12-21. Vol. 10, num. 12, p. 212. DOI : 10.3390/bios10120212.

In-flow measurement of cell-cell adhesion using oscillatory inertial microfluidics

B. R. Mutlu; T. D. Dubash; C. Dietsche; A. Mishra; A. Ozbey et al. 

Lab On A Chip. 2020-05-07. Vol. 20, num. 9, p. 1612-1620. DOI : 10.1039/d0lc00089b.

Three-dimensional electrodes for dielectrophoretic applications

K. Keim / C. Guiducci (Dir.)  

Lausanne, EPFL, 2020. 

Selective Retrieval of Individual Cells from Microfluidic Arrays Combining Dielectrophoretic Force and Directed Hydrodynamic Flow

P-E. M. Thiriet; J. Pezoldt; G. Gambardella; K. Keim; B. Deplancke et al. 

Micromachines. 2020-03-20. Vol. 11, num. 3, p. 322. DOI : 10.3390/mi11030322.

Active Posts in Deterministic Lateral Displacement Devices

J. P. Beech; K. Keim; B. D. Ho; C. Guiducci; J. O. Tegenfeldt 

Advanced Materials Technologies. 2019-07-11.  p. 1900339. DOI : 10.1002/admt.201900339.

On‐chip technology for single‐cell arraying, electrorotation‐based analysis and selective release

K. Keim; M. Rashed; S. Kilchenmann; A. Delattre; G. Antonio et al. 

Electrophoresis. 2019-05-21. Vol. 40, num. 14, p. 1830-1838. DOI : 10.1002/elps.201900097.

Microfluidic-based automated multiplex immunophenotyping and imaging

B. Pelz; D. Migliozzi; G. Cappi; D. Dupouy; M. Gijs 

2018-09-01.  p. S1-S1.

Comparison against current standards of a DNA aptamer for the label-free quantification of tobramycin in human sera employed for therapeutic drug monitoring

E. Tenaglia; A. Ferretti; L. A. Decosterd; D. Werner; T. Mercier et al. 

Journal of Pharmaceutical and Biomedical Analysis. 2018. Vol. 159, p. 341-347. DOI : 10.1016/j.jpba.2018.06.061.

Selection of Structure-Switching DNA Aptamers Binding Soluble Small Molecules and SPR Validation of Enrichment

E. Tenaglia; F. M. Spiga; C. Guiducci 

DNA Nanotechnology; New York, NY: Humana Press, 2018-06-21. p. 183-197.

Microdevice-integrated immunoassays for Point-of-Care Therapeutic Drug Monitoring

E-D. Bojescu / C. Guiducci; J-M. Segura (Dir.)  

Lausanne, EPFL, 2018. 

Isothermal multiple displacement amplification of DNA templates in minimally buffered conditions using phi29 polymerase

E. Tenaglia; Y. Imaizumi; Y. Miyahara; C. Guiducci 

Chemical Communications. 2018-02-02. Vol. 54, num. 17, p. 2158-2161. DOI : 10.1039/C7CC09609G.

Label-free identification of activated T lymphocytes through tridimensional microsensors on chip

E. Rollo; E. Tenaglia; R. Genolet; E. Bianchi; A. Harari et al. 

Biosensors & Bioelectronics. 2017. Vol. 94, p. 193-199. DOI : 10.1016/j.bios.2017.02.047.

Microfluidic and Electrokinetic Manipulation of Single Cells

S. Kilchenmann / C. Guiducci (Dir.)  

Lausanne, EPFL, 2017. 

Analysis of Dielectric Microbead Detection by Impedance Spectroscopy with Nanoribbons

P. Scarbolo; E. Accastelli; T. Ernst; C. Guiducci; L. Selmi 

2016. 16th IEEE International Conference on Nanotechnology (IEEE-NANO), IEEE Nanotechnol Council, Sendai, JAPAN, AUG 22-25, 2016. p. 947-950. DOI : 10.1109/NANO.2016.7751538.

Microfluidic-integrated vertical electrodes employed in impedance-based cytometry

E. Rollo / C. Guiducci (Dir.)  

Lausanne, EPFL, 2016. 

Multi-Wire Tri-Gate Silicon Nanowires Reaching Milli-pH Unit Resolution in One Micron Square Footprint

E. Accastelli; P. Scarbolo; T. Ernst; P. Palestri; L. Selmi et al. 

Biosensors. 2016. Vol. 6, num. 1, p. 9. DOI : 10.3390/bios6010009.

Metal-Coated SU-8 Structures for High-Density 3-D Microelectrode Arrays

S. Kilchenmann; E. Rollo; P. Maoddi; C. Guiducci 

Journal of Microelectromechanical Systems. 2016. Vol. 25, num. 3, p. 425-431. DOI : 10.1109/JMEMS.2016.2539000.

Post-cmos processing and 3d integration based on dry-film lithography

C. Guiducci; Y. Leblebici; Y. Temiz 

US9412728; US2015371978; WO2014020479; WO2014020479.


More DNA–Aptamers for Small Drugs: A Capture–SELEX Coupled with Surface Plasmon Resonance and High-Throughput Sequencing

F. M. Spiga; P. Maietta; C. Guiducci 

ACS Combinatorial Science. 2015. Vol. 17, num. 5, p. 326-333. DOI : 10.1021/acscombsci.5b00023.

Label-Free Detection of Tobramycin in Serum by Transmission-Localized Surface Plasmon Resonance

G. Cappi; F. M. Spiga; Y. Moncada; A. Ferretti; M. Beyeler et al. 

Analytical Chemistry. 2015. Vol. 87, num. 10, p. 5278-5285. DOI : 10.1021/acs.analchem.5b00389.

Quantification of low molecular weight drugs

A. Ferretti / C. Guiducci (Dir.)  

Lausanne, EPFL, 2015. 

Tri-gate silicon nanowire transistors for ultra-low pH resolution and improved scalability

E. Accastelli / C. Guiducci (Dir.)  

Lausanne, EPFL, 2014. 

Label-free Analytics by Transmission Localized-SPR and its Application to Small Molecules Monitoring in Serum

G. Cappi / C. Guiducci; L. Benini (Dir.)  

Lausanne, EPFL, 2014. 

Hybridization chain reaction performed on a metal surface as a means of signal amplification in SPR and electrochemical biosensors

F. M. Spiga; A. Bonyar; B. Ring; M. Onofri; A. Vinelli et al. 

Biosensors & Bioelectronics. 2014. Vol. 54, p. 102-108. DOI : 10.1016/j.bios.2013.10.036.

Digital approaches in Electronic biochips

C. Guiducci; E. Accastelli; F. M. Spiga 

2013. IEEE International Electron Devices Meeting (IEDM), 2013, Washington, DC, USA, December 9-11 2013. p. 8.3.1-8.3.4. DOI : 10.1109/IEDM.2013.6724586.

Comparison between front- and back-gating of Silicon Nanoribbons in real-time sensing experiments

E. Accastelli; G. Cappi; J. Buckley; T. Ernst; C. Guiducci 

2013. 13th IEEE Conference on Nanotechnology (IEEE-NANO), 2013, Beijing, China, August 5-8, 2013. DOI : 10.1109/NANO.2013.6721024.

A 0.18 mu m Biosensor Front-End Based on 1/f Noise, Distortion Cancelation and Chopper Stabilization Techniques

V. Balasubramanian; P-F. Ruedi; Y. Temiz; A. Ferretti; C. Guiducci et al. 

IEEE Transactions On Biomedical Circuits And Systems. 2013. Vol. 7, num. 5, p. 660-673. DOI : 10.1109/Tbcas.2012.2234121.

Another transistor-based revolution: on-chip qPCR

C. Guiducci; F. M. Spiga 

Nature Methods. 2013. Vol. 10, num. 7, p. 617-618. DOI : 10.1038/nmeth.2525.

Metal-coated silicon micropillars for freestanding 3D-electrode arrays in microchannels

S. C. Kilchenmann; E. Rollo; E. Bianchi; C. Guiducci 

Sensors And Actuators B-Chemical. 2013. Vol. 185, p. 713-719. DOI : 10.1016/j.snb.2013.05.037.

Microfluidics for in vitro biomimetic shear stress-dependent leukocyte adhesion assays

E. Bianchi; R. Molteni; R. Pardi; G. Dubini 

Journal Of Biomechanics. 2013. Vol. 46, num. 2, p. 276-283. DOI : 10.1016/j.jbiomech.2012.10.024.

Post-CMOS Processing and 3-D Integration Based on Dry-Film Lithography

Y. Temiz; C. Guiducci; Y. Leblebici 

IEEE Transactions on Components, Packaging and Manufacturing Technology. 2013. Vol. 3, num. 9, p. 1458-1466. DOI : 10.1109/TCPMT.2012.2228004.

Peak Shift Measurement of Localized Surface Plasmon Resonance by a Portable Electronic System

G. Cappi; E. Accastelli; V. Cantale; M. A. Rampi; L. Benini et al. 

Sensors and Actuators B: Chemical. 2013. Vol. 176, p. 225-231. DOI : 10.1016/j.snb.2012.07.085.

Overview of Micro- and Nano-Technology Tools for Stem Cell Applications: Micropatterned and Microelectronic Devices

S. Cagnin; E. Cimetta; C. Guiducci; P. Martini; G. Lanfranchi 

Sensors. 2012. Vol. 12, num. 11, p. 15947-15982. DOI : 10.3390/s121115947.

A Portable Setup for Molecular Detection by Transmission LSPR

G. Cappi; E. Accastelli; F. M. Spiga; V. Cantale; M. A. Rampi et al. 

2012. XXI International Materials Research Congress, Cancun, Mexico, August 12-17, 2012. p. 27-32. DOI : 10.1557/opl.2012.1593.

Detecting particles flowing through interdigitated 3D microelectrodes

E. Bianchi; E. Rollo; S. Kilchenmann; F. C. M. Bellati; E. Accastelli et al. 

2012. 34th Annual International Conference of the IEEE EMBS, San Diego, California, USA, August 28 – September 1, 2012. p. 5002-5005. DOI : 10.1109/EMBC.2012.6347116.

A Comparative Study on Fabrication Techniques for On-Chip Microelectrodes

Y. Temiz; A. Ferretti; Y. Leblebici; C. Guiducci 

Lab on a Chip Journal, Royal Society of Chemistry. 2012. Vol. 12, num. 22, p. 4920-4928. DOI : 10.1039/c2lc40582b.

3D Integration Technology for Lab-on-a-Chip Applications

Y. Temiz / Y. Leblebici; C. Guiducci (Dir.)  

Lausanne, EPFL, 2012. 

A CMOS Compatible Chip-to-Chip 3D Integration Platform

Y. Temiz; M. Zervas; C. Guiducci; Y. Leblebici 

2012. Electronic Components and Technology Conference (ECTC), San Diego, California, USA, May 29-June 2, 2012. p. 555-560. DOI : 10.1109/ECTC.2012.6248884.

Interview with Carlotta Guiducci

C. Guiducci 

Electronics Letters- IEE. 2011. Vol. 47, p. S21. DOI : 10.1049/el.2011.3018.

3D Integration Technology for Lab-on-a-Chip Applications

Y. Temiz; S. Kilchenmann; Y. Leblebici; C. Guiducci 

Electronics Letters- IEE. 2011. Vol. 47, p. 22-24. DOI : 10.1049/el.2011.2683.

Die-Level TSV Fabrication Platform for CMOS-MEMS Integration

Y. Temiz; M. Zervas; C. Guiducci; Y. Leblebici 

2011. The 16th International Conference on Solid-State Sensors, Actuators and Microsystems, Beijing, China, June 5-9, 2011. p. 1799-1802. DOI : 10.1109/TRANSDUCERS.2011.5969555.

Model of an Interdigitated Microsensor to Detect and Quantify Cells Flowing in a Test Chamber

E. Bianchi; F. Boschetti; G. Dubini; C. Guiducci 

2010. 6th annual COMSOL Conference, Paris, France, November 17-19.

Robust Microelectrodes Developed for Improved Stability in Electrochemical Characterization of Biomolecular Layers

Y. Temiz; A. Ferretti; E. Accastelli; Y. Leblebici; C. Guiducci 

2010. 9th Annual IEEE Conference on Sensors, Hawaii, USA, November 1-4, 2010. p. 1051-1055. DOI : 10.1109/ICSENS.2010.5690737.

Regenerative Circuits for Rapid Biosensing

A. Biyabani; C. Guiducci; G. De Micheli 

2010. 17th IEEE International Conference on Electronics, Circuits, and Systems, ICECS 2010, Athens, Greece, December 12-15, 2010. p. 567-570. DOI : 10.1109/ICECS.2010.5724575.

Integrating Bio-sensing Functions on CMOS Chips

C. Guiducci; Y. Temiz; Y. Leblebici; E. Accastelli; A. Ferretti et al. 

2010. 2010 Asia Pacific Conference on Circuits and Systems (APCCAS 2010), Kuala Lumpur, Malaysia, December 6 – 9. p. 548-551. DOI : 10.1109/APCCAS.2010.5775088.

Overview of Electrochemical DNA Biosensors: New Approaches to Detect the Expression of Life

S. Cagnin; M. Caraballo; C. Guiducci; P. Martini; M. Ross et al. 

Sensors. 2009. Vol. 9, num. 4, p. 3122-3148. DOI : 10.3390/s90403122.

Real-time high-sensitivity impedance measurement interface for tethered BLM biosensor arrays

Y. Temiz; F. K. Gurkaynak; S. Terrettaz; H. Vogel; G. De Micheli et al. 

2008. 7th IEEE Sensors Conference, Lecce, Italy, October 26-29, 2008. p. 650-653. DOI : 10.1109/ICSENS.2008.4716525.

High Parallelism, Portability, and Broad Accessibility: Technologies for Genomics


ACM Journal on Emerging Technologies in Computing Systems. 2008. Vol. 4, num. 1, p. 3:1-3:39. DOI : 10.1145/1330521.1330524.

Innovative optoelectronic approaches to biomolecular analysis with arrays of silicon devices

C. Guiducci; C. Stagni; M. Brocchi; M. Lanzoni; B. Ricco et al. 

Vlsi-Soc: Research Trends in Vlsi and Systems on Chip. 2008.  p. 37-53. DOI : 10.1007/978-0-387-74909-9_3.

Novel front-end circuit architectures for integrated bio-electronic interfaces

C. Guiducci; A. Schmid; F. K. Guerkaynak; Y. Leblebici 

2008.  p. 1170-1175.

Interface Layering Phenomena in Capacitance Detection of DNA with Biochips

S. Carrara; F. K. Gürkaynak; C. Guiducci; C. Stagni; L. Benini et al. 

Sensors & Transducers Journal. 2007. Vol. 76, num. 2, p. 969-977.

A fully electronic label-free DNA sensor chip

C. Stagni; C. Guiducci; L. Benini; B. Ricco; S. Carrara et al. 

Ieee Sensors Journal. 2007. Vol. 7, num. 3-4, p. 577-585. DOI : 10.1109/jsen.2007.891990.

Electronic detection of DNA hybridization: Toward CMOS microarrays

L. Benini; C. Paulus; C. Guiducci 

Ieee Design & Test of Computers. 2007. Vol. 24, num. 1, p. 38-48. DOI : 10.1109/MDT.2007.12.

Fully Electronic CMOS DNA Detection Array Based on Capacitance Measurement with On-Chip Analog-to-Digital Conversion

C. Stagni Degli Esposti; C. Guiducci; C. Paulus; M. Schienle; M. Augustyniak et al. 

2006. Solid-State Circuits Conference, 2006. ISSCC 2006, San Francisco, CA, Feb 6-9, 2006. p. 69-78. DOI : 10.1109/ISSCC.2006.1696035.

Metallic oxide CdIn2O4 films for the label free electrochemical detection of DNA hybridization

A. Zebda; V. Stambouli; M. Labeau; C. Guiducci; J. P. Diard et al. 

Biosensors & Bioelectronics. 2006. Vol. 22, num. 2, p. 178-184. DOI : 10.1016/j.bios.2005.12.012.

Semiconductor oxide based electrodes for the label-free electrical detection of DNA hybridization: Comparison between Sb doped SnO2 and CdIn2O4

V. Stambouli; A. Zebda; E. Appert; C. Guiducci; M. Labeau et al. 

Electrochimica Acta. 2006. Vol. 51, num. 24, p. 5206-5214. DOI : 10.1016/j.electacta.2006.03.045.

Development and functionalisation of Sb doped SnO2 thin films for DNA biochip applications

V. Stambouli; M. Labeau; I. Matko; B. Chenevier; O. Renault et al. 

Sensors and Actuators B-Chemical. 2006. Vol. 113, num. 2, p. 1025-1033. DOI : 10.1016/j.snb.2005.03.108.

CMOS DNA sensor array with integratedA/D conversion based on label-free capacitance measurement

C. Stagni; C. Guiducci; L. Benini; B. Ricco; S. Carrara et al. 

Ieee Journal of Solid-State Circuits. 2006. Vol. 41, num. 12, p. 2956-2964. DOI : 10.1109/jssc.2006.884867.

Micro-array device, for DNA recognition, includes micro-sensors to output signals indicating absorption of ultraviolet radiation in micro-location, when traversed by UV beam during hybridization process

B. Ricco; C. Guiducci; L. Benini 

US2009069192; EP1864116; WO2006095257; WO2006095257; WO2006095257; CA2601021; ITBO20050142.


Microelectrodes on a silicon chip for label-free capacitive DNA sensing

C. Guiducci; C. Stagni; A. Fischetti; U. Mastromatteo; L. Benini et al. 

Ieee Sensors Journal. 2006. Vol. 6, num. 5, p. 1084-1093. DOI : 10.1109/jsen.2006.877879.

Innovative optoelectronic approaches to biomolecular analysis with arrays of silicon devices

C. Guiducci; C. Stagni; M. Brocchi; M. Lanzoni; B. Ricco et al. 

2006.  p. 169-174. DOI : 10.1109/VLSISOC.2006.313228.

Hydrogenated amorphous silicon ultraviolet sensor for deoxyribonucleic acid analysis

G. de Cesare; D. Caputo; A. Nascetti; C. Guiducci; B. Ricco 

Applied Physics Letters. 2006. Vol. 88, num. 8, p. 083904. DOI : 10.1063/1.2179608.

Wireless sensor networks: Enabling technology for ambient intelligence

L. Benini; E. Farella; C. Guiducci 

Microelectronics Journal. 2006. Vol. 37, num. 12, p. 1639-1649. DOI : 10.1016/j.mejo.2006.04.021.

‘Label-free’ DNA analysis using a-Si:H UV sensors

D. Caputo; G. de Cesare; A. Nascetti; C. Guiducci; B. Riccò 

2005. 1st International Conference on Sensing Technology, Palmerston North, New Zealand, November 21-23, 2005.

Hardware-software design of a smart sensor for fully-electronic DNA hybridization detection

C. Stagni; C. Guiducci; M. Lanzoni; L. Benim; B. Ricco 

2005. Automation and Test in Europe Conference and Exhibition (DATE 05), Munich, GERMANY, MAR 07-11, 2005. p. 198-203.

DNA detection by integrable electronics

C. Guiducci; C. Stagni; G. Zuccheri; A. Bogliolo; L. Benini et al. 

Biosensors & Bioelectronics. 2004. Vol. 19, num. 8, p. 781-787. DOI : 10.1016/s0956-5663(03)00266-5.

Characterization of effective mobility by split C(V) technique in N-MOSFETs with ultra-thin gate oxides

F. Lime; C. Guiducci; R. Clerc; G. Ghibaudo; C. Leroux et al. 

Solid-State Electronics. 2003. Vol. 47, num. 7, p. 1147-1153. DOI : 10.1016/s0038-1101(03)00049-2.