Recent work involving the BioEM facility


Korrell, K. V., Disser, J., Parley, K., Vadisiute, A., Requena‐Komuro, M., Fodder, H., et al. (2019). Differential effect on myelination through abolition of activity‐dependent synaptic vesicle release or reduction of overall electrical activity of selected cortical projections in the mouse. J. Anat., joa.12974. doi:10.1111/joa.12974.

D’Amico, D., Mottis, A., Potenza, F., Sorrentino, V., Li, H., Romani, M., et al. (2019). The RNA-Binding Protein PUM2 Impairs Mitochondrial Dynamics and Mitophagy During Aging. Mol. Cell73, 775-787.e10. doi:10.1016/j.molcel.2018.11.034.

Battistella, C., Guiet, R., Burri, O., Seitz, A., Escrig, S., Knott, G. W., et al. (2019). Cellular Uptake and Intracellular Trafficking of Poly( N-(2-Hydroxypropyl) Methacrylamide). Biomacromolecules20, 231–242. doi:10.1021/acs.biomac.8b01372.

Bernard-Marissal, N., van Hameren, G., Juneja, M., Pellegrino, C., Louhivuori, L., Bartesaghi, L., et al. (2019). Altered interplay between endoplasmic reticulum and mitochondria in Charcot–Marie–Tooth type 2A neuropathy. Proc. Natl. Acad. Sci.116, 2328–2337. doi:10.1073/pnas.1810932116.


Calì, C., Wawrzyniak, M., Becker, C., Maco, B., Cantoni, M., Jorstad, A., Nigro, B., Grillo, F., De Paola, V., Fua, P., et al. (2018). The effects of aging on neuropil structure in mouse somatosensory cortex-A 3D electron microscopy analysis of layer 1. PLoS One 13, e0198131.

El-Boustani, S., Ip, J.P.K., Breton-Provencher, V., Knott, G.W., Okuno, H., Bito, H., and Sur, M. (2018). Locally coordinated synaptic plasticity of visual cortex neurons in vivo. Science (80-). 360.

Gjoni, E., Aguet, C., Sahlender, D.A., Knott, G., and Schneggenburger, R. (2018). Ultrastructural basis of strong unitary inhibition in a binaural neuron. J. Physiol. 596, 4969–4982.

Van der Henst C, Vanhove AS, Drebes Dörr NC, Stutzmann S, Stoudmann C, Clerc S, Scrignari T, Maclachlan C, Knott G, Blokesch M (2018). Molecular insights into Vibrio cholerae’s intra-amoebal host-pathogen interactions. Nat Com.

Jorstad, A., Blanc, J., and Knott, G. (2018). NeuroMorph: A Software Toolset for 3D Analysis of Neurite Morphology and Connectivity. Front. Neuroanat. 12, 59.

Maclachlan, C., Sahlender, D. A., Hayashi, S., Molnár, Z., and Knott, G. (2018). Block Face Scanning Electron Microscopy of Fluorescently Labeled Axons Without Using Near Infra-Red Branding. Front. Neuroanat.12, 1–8.

Real, R., Peter, M., Trabalza, A., Khan, S., Smith, M.A., Dopp, J., Barnes, S.J., Momoh, A., Strano, A., Volpi, E., et al. (2018). In vivo modeling of human neuron dynamics and Down syndrome. Science eaau1810.

Gala R, Lebrecht D, Sahlender DA, Jorstad A, Knott G, Holtmaat A, Stepanyants A (2017) Computer assisted detection of axonal bouton structural plasticity in in vivo time-lapse images. Elife 6

Bacq A, Astori S, Gebara E, Tang W, Silva BA, Sanchez-Mut J, Grosse J, Guillot de Suduiraut I, Zanoletti O, Maclachlan C, Knott GW, Gräff J, Sandi C (2018). Amygdala GluN2B-NMDAR dysfunction is critical in abnormal aggression of neurodevelopmental origin induced by St8sia2 deficiency. Mol Psychiatry.

Lathuilière A, Valdés P, Papin S, Cacquevel M, Maclachlan C, Knott GW, Muhs A, Paganetti P, Schneider BL (2017) Motifs in the tau protein that control binding to microtubules and aggregation determine pathological effects. Sci Rep 7:13556

Lee RFS, Riedel T, Escrig S, Maclachlan C, Knott GW, Davey CA, Johnsson K, Meibom A, Dyson PJ (2018). Differences in cisplatin distribution in sensitive and resistant ovarian cancer cells: a TEM/NanoSIMS study. Metallomics.