Here we provide video tutorials and other resources to help other research laboratories use the approaches and tools that we have developed. Some of these approaches require surgical manipulation of animals. We do our best to reduce the number of animals we use for experiments. We also make every effort to minimize harm. Our investigation of flies (Drosophila melanogaster) is in line with a general effort to Replace, Reduce, and Refine in animal research. Please see these links for more information about more about the 3Rs in general, in Switzerland, and at EPFL.
Tethering flies for high-resolution behavioral studies.
Dissections for neural recordings in the motor system (VNC) of behaving flies.
Tools and dissections for long-term (lifetime-scale) neural recordings in the motor system (VNC) of behaving flies.
Tools and approach reported in Hermans, Kaynak et al., Nature Communications 2022
NeuroMechFly, a neuromechanical simulation of the adult fly.
Code and approach reported in Lobato-Ríos et al., Nature Methods 2022
LifePose3D, 3D pose estimation with fewer cameras
Code and approach reported in Gosztolai, Günel et al., Nature Methods 2022
DeepFly3D, 3D pose estimation for tethered flies.
Code and approach reported in Günel et al., Elife 2019