La Manno Lab – Laboratory of Neurodevelopmental Systems Biology

Our research focuses on understanding how the cell types in the nervous system are made. We are particularly interested in describing the sequence of states that embryonic stem cells go through during their differentiation towards mature neurons in the central nervous system and the retina.

Team

Learn more about us

The people in the lab

Learn more about us

LATEST PUBLICATIONS

A cell fitness selection model for neuronal survival during development

Y. Wang; H. Wu; P. Fontanet; S. Codeluppi; N. Akkuratova et al. 

Nature Communications. 2019-09-12. Vol. 10, p. 4137. DOI : 10.1038/s41467-019-12119-3.

Detailed record

Full text – View at publisher

Single-cell transcriptional logic of cell-fate specification and axon guidance in early-born retinal neurons

Q. Lo Giudice; M. Leleu; G. La Manno; P. J. Fabre 

Development. 2019-09-01. Vol. 146, num. 17, p. dev178103. DOI : 10.1242/dev.178103.

Detailed record

View at publisher

Spatial organization of the somatosensory cortex revealed by osmFISH

S. Codeluppi; L. E. Borm; A. Zeisel; G. La Manno; J. A. van Lunteren et al. 

Nature Methods. 2018-11-01. Vol. 15, num. 11, p. 932-935. DOI : 10.1038/s41592-018-0175-z.

Detailed record

View at publisher


Selected Publications

EPFL and AbbVie collaborate to advance Alzheimer's research

— EPFL and AbbVie, a global biopharmaceutical company, have entered into a three-year collaboration agreement to advance research in and development of novel mechanism-based therapeutic strategies for Alzheimer’s disease.

EPFL bioengineering team wins global iGEM competition

— EPFL’s student bioengineering team has won the Grand Prize of the 2019 International Genetically Engineered Machine (iGEM) competition, as well as the Best Environment Project. Their winning project, ViTEST, is a diagnostic test for grapevine disease.

Turning a dangerous toxin into a biosensor

— Some bacteria release a toxin that forms pores on other cells. EPFL scientists have studied the pore-forming toxin aerolysin and genetically engineered it to be used as a high-resolution sensor for biological molecules like DNA and proteins.

All news

Contact

Head of Laboratory : Gioele La Manno

Office : AAB 0 09

Phone :  41 21 69 38446

Mail : gioel[email protected]

Administrative Assistant : Marie-France Radigois

Office : AI 2145

Phone :  41 21 69 30904

Mail : [email protected]

Hot to get there