La Manno Lab – Laboratory of Neurodevelopmental Systems Biology

Our research focuses on understanding how the cell types in the nervous system are made. We are particularly interested in describing the sequence of states that embryonic stem cells go through during their differentiation towards mature neurons in the central nervous system and the retina.

The people in the lab


The lipotype hypothesis

G. D’Angelo; G. La Manno 

Nature Reviews Molecular Cell Biology. 2023. Vol. 24, p. 1–2. DOI : 10.1038/s41580-022-00556-w.

Self-organizing in vitro mouse neural tube organoids mimic embryonic development

J. Park; H-A. Hsiung; I. Khven; G. La Manno; M. P. Lutolf 

Development. 2022-10-01. Vol. 149, num. 20, p. dev. DOI : 10.1242/dev.201052.

Molecular profiling of stem cell-derived retinal pigment epithelial cell differentiation established for clinical translation

S. Petrus-Reurer; A. R. Lederer; L. Baque-Vidal; I. Douagi; B. Pannagel et al. 

Stem Cell Reports. 2022-06-14. Vol. 17, num. 6, p. 1458-1475. DOI : 10.1016/j.stemcr.2022.05.005.

Selected Publications


Head of Laboratory : Gioele La Manno

Office : AAB 0 09

Phone : +41 21 69 38446

Mail : [email protected]

Administrative Assistant : Marie-France Radigois

Office : AI 2145

Phone : +41 21 69 30904

Mail : [email protected]

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