La Manno Lab - Laboratory of Neurodevelopmental Systems Biology

Our research focuses on understanding how the cell types in the nervous system are made. We are particularly interested in describing the sequence of states that embryonic stem cells go through during their differentiation towards mature neurons in the central nervous system and the retina.

Team

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LATEST PUBLICATIONS

Spatial organization of the somatosensory cortex revealed by osmFISH

S. Codeluppi; L. E. Borm; A. Zeisel; G. La Manno; J. A. van Lunteren et al.

Nature Methods. 2018-11-01. Vol. 15, num. 11, p. 932-935. DOI : 10.1038/s41592-018-0175-z.

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Molecular Architecture of the Mouse Nervous System

A. Zeisel; H. Hochgerner; P. Lönnerberg; A. Johnsson; F. Memic et al.

Cell. 2018-08-09. Vol. 174, num. 4, p. 999-1014.e22. DOI : 10.1016/j.cell.2018.06.021.

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RNA velocity of single cells

G. La Manno; R. Soldatov; A. Zeisel; E. Braun; H. Hochgerner et al.

Nature. 2018-08-08. Vol. 560, num. 7719, p. 494-498. DOI : 10.1038/s41586-018-0414-6.

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Selected Publications

RNA velocity of single cells

Molecular architecture of the mouse nervous system

Molecular diversity of midbrain development in mouse, human, and stem cells

Are fertility apps useful?

Published:16.07.19 — Researchers at EPFL and Stanford have carried out an analysis of the largest datasets from fertility awareness apps. Analyzing data from 200,000 users of the apps Sympto and Kindara, they have been able to make population-level observations regarding user demographics, tracking behavior patterns and accuracy in measuring menstrual health and ovulation.

Etienne Meylan's group shares in award-winning project with CHUV

Published:08.07.19 — A thoracic surgery project by CHUV has been awarded the Grillo Prize from the European Society of Thoracic Surgeons. The project was a collaboration with a PhD student from Etienne Meylan’s group at EPFL.

EPFL postdoc wins United Mitochondrial Disease Foundation Prize

Published:02.07.19 — Dr Arwen Gao, a postdoc at the lab of Johan Auwerx at EPFL, has won the 2019 Accelerator Prize from the United Mitochondrial Disease Foundation.

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Contact

Head of Laboratory : Gioele La Manno

Office : AAB 0 09

Phone : +41 21 69 38446

Mail : [email protected]

Administrative Assistant : Marie-France Radigois

Office : AI 2145

Phone : +41 21 69 30904

Mail : [email protected]

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