La Manno Lab – Laboratory of Neurodevelopmental Systems Biology

Our research focuses on understanding how the cell types in the nervous system are made. We are particularly interested in describing the sequence of states that embryonic stem cells go through during their differentiation towards mature neurons in the central nervous system and the retina.

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LATEST PUBLICATIONS

Spatial tissue profiling by imaging-free molecular tomography

H. H. Schede; C. G. Schneider; J. Stergiadou; L. E. Borm; A. Ranjak et al.

Nature Biotechnology. 2021-04-19. DOI : 10.1038/s41587-021-00879-7.

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Cell type prioritization in single-cell data

M. A. Skinnider; J. W. Squair; C. Kathe; M. A. Anderson; M. Gautier et al.

Nature Biotechnology. 2020-07-20. DOI : 10.1038/s41587-020-0605-1.

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The emergence and promise of single-cell temporal-omics approaches

A. R. Lederer; G. La Manno

Current Opinion In Biotechnology. 2020-06-01. Vol. 63, p. 70-78. DOI : 10.1016/j.copbio.2019.12.005.

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Selected Publications

Michaël Unser, academic director of the EPFL Imaging Center, and Laurène Donati, executive director © 2021 Alain Herzog

New Imaging Center Pools the Know-How of Five EPFL Schools

Published:16.06.21 — EPFL has just opened a new imaging center to serve as a hub for state-of-the-art technology in imaging systems. The only one of its kind in Switzerland, the center pools the imaging expertise that is currently housed at nearly a hundred laboratories in five EPFL schools. The goal is to facilitate cross-disciplinary research and anchor EPFL’s position at the cutting edge of imaging technology for research applications.

Andrea Ablasser. Credit: EPFL - Alain Herzog

EMBO Gold Medal 2021 awarded to Andrea Ablasser

Published:15.06.21 — Andrea Ablasser, Professor at EPFL, the Swiss Federal Institute of Technology in Lausanne, Switzerland, is the recipient of the EMBO Gold Medal 2021. With the medal and an award of 10,000 euros, EMBO recognizes outstanding achievements of scientists under the age of 40 in Europe.

The cancer exosome is detected when the light interacts with the silicon nanostructures. © Yasaman Jahani / 2021 EPFL

Using light to monitor cancer

Published:08.06.21 — Researchers at EPFL have developed a technology based on nanophotonics and data science to detect and monitor cancer biomarkers at an early stage. Their research is published in Nature Communications.

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