La Manno Lab - Laboratory of Neurodevelopmental Systems Biology

Our research focuses on understanding how the cell types in the nervous system are made. We are particularly interested in describing the sequence of states that embryonic stem cells go through during their differentiation towards mature neurons in the central nervous system and the retina.

The people in the lab


Spatial organization of the somatosensory cortex revealed by osmFISH

S. Codeluppi; L. E. Borm; A. Zeisel; G. La Manno; J. A. van Lunteren et al. 

Nature Methods. 2018-11-01. Vol. 15, num. 11, p. 932-935. DOI : 10.1038/s41592-018-0175-z.

Molecular Architecture of the Mouse Nervous System

A. Zeisel; H. Hochgerner; P. Lönnerberg; A. Johnsson; F. Memic et al. 

Cell. 2018-08-09. Vol. 174, num. 4, p. 999-1014.e22. DOI : 10.1016/j.cell.2018.06.021.

RNA velocity of single cells

G. La Manno; R. Soldatov; A. Zeisel; E. Braun; H. Hochgerner et al. 

Nature. 2018-08-08. Vol. 560, num. 7719, p. 494-498. DOI : 10.1038/s41586-018-0414-6.

Selected Publications

RNA velocity of single cells

Molecular architecture of the mouse nervous system

Molecular diversity of midbrain development in mouse, human, and stem cells


Head of Laboratory : Gioele La Manno

Office : AAB 0 09

Phone : +41 21 69 38446

Mail : [email protected]

Administrative Assistant : Marie-France Radigois

Office : AI 2145

Phone : +41 21 69 30904

Mail : [email protected]

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