La Manno Lab – Laboratory of Neurodevelopmental Systems Biology

Our research focuses on understanding how the cell types in the nervous system are made. We are particularly interested in describing the sequence of states that embryonic stem cells go through during their differentiation towards mature neurons in the central nervous system and the retina.

The people in the lab


Molecular profiling of stem cell-derived retinal pigment epithelial cell differentiation established for clinical translation

S. Petrus-Reurer; A. R. Lederer; L. Baque-Vidal; I. Douagi; B. Pannagel et al. 

Stem Cell Reports. 2022-06-14. Vol. 17, num. 6, p. 1458-1475. DOI : 10.1016/j.stemcr.2022.05.005.

Sphingolipids control dermal fibroblast heterogeneity

L. Capolupo; I. Khven; A. R. Lederer; L. Mazzeo; G. Glousker et al. 

Science. 2022-04-15. Vol. 376, num. 6590, p. 262-262. DOI : 10.1126/science.abh1623.

Clonal relations in the mouse brain revealed by single-cell and spatial transcriptomics

M. Ratz; L. von Berlin; L. Larsson; M. Martin; J. O. Westholm et al. 

Nature Neuroscience. 2022-02-24. DOI : 10.1038/s41593-022-01011-x.

Selected Publications


Head of Laboratory : Gioele La Manno

Office : AAB 0 09

Phone : +41 21 69 38446

Mail : [email protected]

Administrative Assistant : Marie-France Radigois

Office : AI 2145

Phone : +41 21 69 30904

Mail : [email protected]

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