Publications

Microsecond Time-Resolved Cryo-Electron Microscopy

Ulrich J. Lorenz. Arxiv. 2402.16519 (2024)


Shaped Laser Pulses for Microsecond Time-Resolved Cryo-EM: Outrunning Crystallization During Flash Melting

Constantin R. Krüger, Nathan J. Mowry, Marcel Drabbels, Ulrich J. Lorenz. J. Phys. Chem. Lett. 15, 4244−4248 (2024)


Flash Melting Amorphous Ice
Nathan J. Mowry, Constantin R. Krüger, Gabriele Bongiovanni, Marcel Drabbels, Ulrich J. Lorenz. J.  Chem. Phys. Vol. 160, Issue 18 (2024)

 


Fast Viral Dynamics Revealed by Microsecond Time-Resolved Cryo-EM
Oliver. F. Harder, Sarah V. Barrass, Marcel Drabbels, Ulrich J. Lorenz. Nat. Commun. 14, 5649 (2023)


Near-atomic resolution reconstructions from in situ revitrified cryo sample
Gabriele
Bongiovanni
, Oliver F. Harder, Jonathan M. Voss, Marcel Drabbels, Ulrich J. Lorenz. J. Struct. Biol. D79, 473-478 (2023)


Electron diffraction of deeply supercooled water in no man’s land
Constantin R. Krüger, Nathan J. Mowry, Gabriele Bongiovanni, Marcel Drabbels, Ulrich J. Lorenz. Nat. Commun. 14, 2812 (2023)
EPFL Press release : Breaking the ice over a 40-year problem of supercooled water
Editors’Highlight


Microsecond melting and revitrification of cryo samples with a correlative light-electron microscopy approach

Gabriele Bongiovanni, Oliver F. Harder, Marcel Drabbels, Ulrich J. Lorenz.  Frontiers 9, 1044509 (2022)

 


Visualizing Nanoscale Dynamics with Time-resolved Electron Microscopy J.M. Voss, P.K. Olshin, M. Drabbels, U.J. Lorenz. Chimia 76, 754-762 (2022)


Microsecond Melting and Revitrification of Cryo Samples: Protein Structure and Beam-Induced Motion. O.F. Harder, J.M. Voss, P.K. Olshin, M. Drabbels, U.J. Lorenz. Struct. Biol. D.78, 883–889 (2022)

 

 


Accurate Time Zero Determination in an Ultrafast Transmission Electron Microscope without Energy Filter. P.K. Olshin, J.M. Voss, M. Drabbels, U.J. Lorenz. Appl. Phys. Lett. 120, 104103 (2022)

 

 


Microsecond Melting and Revitrification of Cryo Samples. J.M. Voss, O.F. Harder, P.K. Olshin, M. Drabbels, U.J. Lorenz. Struct. Dyn. 8, 054302 (2021)

Editor’s Pick

 


The Fragmentation Mechanism of Gold Nanoparticles in Water Under Femtosecond Laser Irradiation. G. Bongiovanni, P.K. Olshin, C. Yan, J.M. Voss, M. Drabbels, U.J. Lorenz. Nanoscale Adv. 3, 5277–5283 (2021)

Highlighted by Nanoscale Advances on Twitter and Facebook


Rapid Melting and Revitrification as an Approach to Microsecond Time-Resolved Cryo-Electron Microscopy. J.M. Voss, O.F. Harder, P.K. Olshin, M. Drabbels, U.J. Lorenz. Chem. Phys. Lett. 778, 138812 (2021)

Frontiers Article 

EPFL press release: Laser Improves the Time Resolution of CryoEM

 


Atomic-Resolution Imaging of Fast Nanoscale Dynamics with Bright Electron Pulses. P.K. Olshin, G. Bongiovanni, M. Drabbels, U.J. Lorenz. Nano Lett. 21, 612–618 (2021)

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Characterization of a Time-Resolved Electron Microscope with a Schottky Field Emission Gun. P.K. Olshin, M. Drabbels, U.J. Lorenz. Struct. Dyn. 7, 054304 (2020)


Intense Microsecond Electron Pulses from a Schottky Emitter. G. Bongiovanni, P.K. Olshin, M. Drabbels, U.J. Lorenz. Appl. Phys. Lett. 116, 234103 (2020)

Editor’s Choice

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Real-Time Observation of Jumping and Spinning Nanodroplets. P.K. Olshin, J.M. Voss, M. Drabbels, U.J. Lorenz. Struct. Dyn. 7, 011101 (2020)

 


In Situ Observation of Coulomb Fission of Individual Plasmonic Nanoparticles. J.M. Voss, P.K. Olshin, R. Charbonnier, M. Drabbels, U.J. Lorenz. ACS Nano 13, 12445–12451 (2019)

 

 


Observing Liquid Flow in Nanotubes by 4D Electron Microscopy. U.J. Lorenz, A.H. Zewail. Science 344, 1496–1500 (2014)

Highlighted by Phys.org: Watching nanoscale fluids flow

Liquid flow in nanotubes

Structural Melting of an Amino Acid Dimer upon Intersystem Crossing. U.J. Lorenz, T.R. Rizzo. J. Am. Chem. Soc. 136, 14974–14980 (2014)

 


Biomechanics of DNA Structures Visualized by 4D Electron Microscopy. U.J. Lorenz, A.H. Zewail. Proc. Natl. Acad. Sci. 110, 2822–2827 (2013)

Back cover of Physics Today: Visualizing DNA Biomechanics. Physics Today 66, 84 (2013)

Highlighted in Materials Today: DNA Motion, in Space and Time. Materials Today 16, 53 (2013)

Biomechanics of DNA structures

4D Cryo-Electron Microscopy of Proteins. A.W.P. Fitzpatrick, U.J. Lorenz,  G.M. Vanacore, A.H. Zewail. J. Am. Chem. Soc. 135, 19123–19126 (2013)

 


A Radio Frequency/High Voltage Pulse Generator for the Operation of a Planar Multipole Ion Trap/Time-of-Flight Mass Spectrometer. P. Marmillod,  S. Antonioni, U. J. Lorenz. Rev. of Sci. Instrum. 84, 044707 (2013)

 


Multiple Isomers and Protonation Sites of the Phenylalanine/Serine Dimer. U. J. Lorenz, T. R. Rizzo.  J. Am. Chem. Soc. 134, 11053–11055 (2012)

 


Planar Multipole Ion Trap/Time-of-Flight Mass Spectrometer. U.J. Lorenz, T. R. Rizzo.  Anal. Chem. 83, 7895–7901 (2011)

 


IR Spectroscopy of Isolated Metal-Organic Complexes of Biocatalytic Interest: Evidence for Coordination Number Four for Zn2+(Imidazole)4 A. Lagutschenkov, U.J. Lorenz, O. Dopfer. Int. J. Mass Spectrom. 308, 316–329 (2011)

 


A New Tandem Mass Spectrometer for Photofragment Spectroscopy of Cold, Gas-Phase Molecular Ions. A. Svendsen, U.J. Lorenz, O.V. Boyarkin, T.R. Rizzo. Rev. Sci. Instrum. 81, 073107 (2010)

 


Structure of Zirconocene Complexes Relevant for Olefin Catalysis: Infrared Fingerprint of the Zr(C5H5)2(OH)(CH3CN)+ Cation in the Gas Phase. A. Lagutschenkov, A. Springer, U.J. Lorenz, P. Maitre, O. Dopfer. J. Phys. Chem. A.  114, 2073–2079 (2010)

 


Spectroscopy of Protonated Peptides Assisted by Infrared Multiple Photon Excitation. M. Guidi, U.J. Lorenz, G. Papadopoulos, O.V. Boyarkin, T.R. Rizzo. J. Phys. Chem. A. 113, 797–799 (2009)

 


Infrared Spectra of Isolated Protonated Polycyclic Aromatic Hydrocarbons: Protonated Naphthalene. U.J. Lorenz, N. Solcà, J. Lemaire, P. Maître, O. Dopfer. Angew. Chem. Int. Ed. 46, 6714–6716 (2007)

 


Protonation of Heterocyclic Aromatic Molecules: IR Signature of the Protonation Site of Furan and Pyrrole. U.J. Lorenz, J. Lemaire, P. Maitre, M.-E. Crestoni, S. Fornarini, O. Dopfer. Int. J. Mass Spectrom. 267, 43–53 (2007)

 


Hexaferrocenylbenzene. Y. Yu, A.D. Bond, P.W. Leonard, U.J. Lorenz, T.V. Timofeeva, K.P.C. Vollhardt, D.W. Glenn, A.A. Yakovenko. Chem. Commun. 24,  2572–2574 (2006)

 


Entrance Channel Complexes of Cationic Aromatic SN2 Reactions: IR Spectra of Fluorobenzene+-(H2O)n Clusters.  U. Lorenz, N. Solcà, O. Dopfer. Chem. Phys. Lett. 406, 321–326 (2005)