SAM transmethylation pathway and adenosine recycling to ATP are essential for systemic regulation and immune response

B. Lemaître 

Bacterial-induced Duox-ROS regulates the Imd immune pathway in the gut by modulating the peritrophic matrix

S. Bai; Z. Yao; Z. Cai; Q. Ma; Q. Guo et al. 

An updated proteomic analysis of Drosophila haemolymph after bacterial infection

S. Rommelaere; F. Schüpfer; F. Armand; R. Hamelin; B. Lemaitre 

Layers of immunity: Deconstructing the Drosophila effector response

F. Ryckebusch; Y. Tian; M. Rapin; F. Schüpfer; M. A. Hanson et al. 

Dietary L-Glu sensing by enteroendocrine cells adjusts food intake via modulating gut PYY/NPF secretion

J. Gao; S. Zhang; P. Deng; Z. Wu; B. Lemaitre et al. 

Duox activation in Drosophila Malpighian tubules stimulates intestinal epithelial renewal through a countercurrent flow

Z. Liu; H. Zhang; B. Lemaitre; X. Li 

The conceptual foundations of innate immunity: Taking stock 30 years later

Pradeu Thomas; Thomma Bart T.P.H.; Girarding Stephen; B. Lemaitre 

A humoral stress response protects Drosophila tissues from antimicrobial peptides

S. Rommelaere; A. Carboni; J. F. Bada Juarez; J-P. Boquete; L. A. Abriata et al. 

Pathobiont and symbiont contribute to microbiota homeostasis through Malpighian tubules–gut countercurrent flow in Bactrocera dorsalis

Y. Liu; R. Luo; S. Bai; B. Lemaitre; H. Zhang et al. 

The Drosophila immunity handbook

H. Westlake; M. A. Hanson; B. Lemaitre 

Intestinal commensal bacteria promote Bactrocera dorsalis larval development through vitamin B6 synthesis pathway

J. Gu; Z. Yao; B. Lemaitre; Z. Cai; H. Zhang et al. 

Protein target highlights in CASP15: Analysis of models by structure providers

L. T. Alexander; J. Durairaj; A. Kryshtafovych; L. A. Abriata; Y. Bayo et al. 

Ecology-relevant bacteria drive the evolution of host antimicrobial peptides in Drosophila

M. A. Hanson; L. Grollmus; B. Lemaitre 

CERT1 mutations perturb human development by disrupting sphingolipid homeostasis

C. Gehin; M. A. Lone; W. Lee; L. Capolupo; S. Ho et al. 

Antimicrobial peptides do not directly contribute to aging in Drosophila, but improve lifespan by preventing dysbiosis

M. A. Hanson; B. Lemaitre 

Functional characterization of Drosophila melanogaster immune effectors

Compartmentalized PGRP expression along the dipteran Bactrocera dorsalis gut forms a zone of protection for symbiotic bacteria

Z. Yao; Z. Cai; Q. Ma; S. Bai; Y. Wang et al. 

Disproportionate investment in Spiralin B production limits in-host growth and favors the vertical transmission of Spiroplasma insect endosymbionts

F. Masson; S. Rommelaere; F. Schupfer; J-P. Boquete; B. Lemaitre 

Drosophila immunity: the Drosocin gene encodes two host defence peptides with pathogen-specific roles

M. A. Hanson; S. Kondo; B. Lemaitre 

Repeated truncation of a modular antimicrobial peptide gene for neural context

M. Hanson; B. Lemaitre 

Cecropins contribute to Drosophila host defense against a subset of fungal and Gram-negative bacterial infection

A. L. Carboni; M. A. Hanson; S. A. Lindsay; S. A. Wasserman; B. Lemaitre 

A systematic CRISPR approach to understanding the role of Drosophila antimicrobial peptides in immunity in vivo

The role of the Nimrod proteins in the Drosophila immune system

The wall-less bacterium Spiroplasma poulsonii builds a polymeric cytoskeleton composed of interacting MreB isoforms

F. Masson; X. Pierrat; B. Lemaitre; A. Persat 

A secreted factor NimrodB4 promotes the elimination of apoptotic corpses by phagocytes in Drosophila

B. M. Petrignani; S. Rommelaere; K. Hakim‐Mishnaevski; F. F. Masson; E. J. V. Ramond et al. 

The Drosophila Baramicin polypeptide gene protects against fungal infection

M. A. Hanson; L. B. Cohen; A. Marra; I. Iatsenko; S. A. Wasserman et al. 

Drosophila Antimicrobial Peptides and Lysozymes Regulate Gut Microbiota Composition and Abundance

A. Marra; M. A. Hanson; S. Kondo; B. Erkosar; B. Lemaitre 

The iron transporter Transferrin 1 mediates homeostasis of the endosymbiotic relationship between Drosophila melanogaster and Spiroplasma poulsonii

A. Marra; F. Masson; B. Lemaitre 

Dual proteomics of Drosophila melanogaster hemolymph infected with the heritable endosymbiont Spiroplasma poulsonii

F. F. Masson; S. Rommelaere; A. Marra; F. Schüpfer; B. Lemaitre 

Rapid molecular evolution of Spiroplasma symbionts of Drosophila

M. Gerth; H. Martinez-Montoya; P. Ramirez; F. Masson; J. S. Griffin et al. 

Autophagy as a Gatekeeper of Intestinal Homeostasis

X. Li; B. Lemaitre 

Steroid‐dependent switch of OvoL/Shavenbaby controls self‐renewal versus differentiation of intestinal stem cells

S. Al Hayek; A. Alsawadi; Z. Kambris; J. P. Boquete; J. Bohère et al. 

The role of immune effectors in controlling Drosophila-microbes interactions

Transformation of the Drosophila Sex-Manipulative Endosymbiont Spiroplasma poulsonii and Persisting Hurdles for Functional Genetic Studies

F. Masson; F. Schuepfer; C. Jollivet; B. Lemaitre 

Comparative RNA-Seq analyses ofDrosophilaplasmatocytes reveal gene specific signatures in response to clean injury and septic injury

E. Ramond; J. P. Dudzic; B. Lemaitre 

Machiavellian males with high emotional intelligence exhibit fewer depressive symptoms

R. Bianchi; N. Patthey; D. Mirkovic; B. Lemaitre; K. Schlegel 

Iron sequestration by transferrin 1 mediates nutritional immunity in Drosophila melanogaster

I. Iatsenko; A. Marra; J-P. Boquete; J. Pena; B. Lemaitre 

Renal Purge of Hemolymphatic Lipids Prevents the Accumulation of ROS-Induced Inflammatory Oxidized Lipids and Protects Drosophila from Tissue Damage

X. Li; S. Rommelaere; S. Kondo; B. Lemaitre 

The adipokine NimrodB5 regulates peripheral hematopoiesis in Drosophila

E. Ramond; B. Petrignani; J. P. Dudzic; J-P. Boquete; M. Poidevin et al. 

Blind killing of both male and female Drosophila embryos by a natural variant of the endosymbiotic bacterium Spiroplasma poulsonii

F. Masson; S. Calderon-Copete; F. Schuepfer; A. Vigneron; S. Rommelaere et al. 

New insights on Drosophila antimicrobial peptide function in host defense and beyond

M. A. Hanson; B. Lemaitre 

Growing Ungrowable Bacteria: Overview and Perspectives on Insect Symbiont Culturability

F. Masson; B. Lemaitre 

Role of Nimrod receptors in the Drosophila melanogaster cellular immune response

Adult Drosophila Lack Hematopoiesis but Rely on a Blood Cell Reservoir at the Respiratory Epithelia to Relay Infection Signals to Surrounding Tissues

P. S. Bosch; K. Makhijani; L. Herboso; K. S. Gold; R. Baginsky et al. 

Dynamic Evolution of Antimicrobial Peptides Underscores Trade-Offs Between Immunity and Ecological Fitness

M. A. Hanson; B. Lemaitre; R. L. Unckless 

The antimicrobial peptide defensin cooperates with tumour necrosis factor to drive tumour cell death in Drosophila

J-P. Parvy; Y. Yu; A. Dostalova; S. Kondo; A. Kurjan et al. 

Two Nimrod receptors, NimC1 and Eater, synergistically contribute to bacterial phagocytosis in Drosophila melanogaster

C. Melcarne; E. Ramond; J. Dudzic; A. J. Bretscher; E. Kurucz et al. 

Phagocytosis in Drosophila: From molecules and cellular machinery to physiology

C. Melcarne; B. Lemaitre; E. Kurant 

More Than Black or White: Melanization and Toll Share Regulatory Serine Proteases in Drosophila

J. P. Dudzic; M. A. Hanson; I. Iatsenko; S. Kondo; B. Lemaitre 

The Exchangeable Apolipoprotein Nplp2 Sustains Lipid Flow and Heat Acclimation in Drosophila

S. Rommelaere; J-P. Boquete; J. Piton; S. Kondo; B. Lemaitre 

Functional analysis of RIP toxins from the Drosophila endosymbiont Spiroplasma poulsonii

M. G. Garcia-Arraez; F. Masson; J. C. P. Escobar; B. Lemaitre 

Synergy and remarkable specificity of antimicrobial peptides in vivo using a systematic knockout approach

M. A. Hanson; A. Dostálová; C. Ceroni; M. Poidevin; B. Lemaitre 

Evolution of longevity improves immunity in Drosophila

D. K. Fabian; K. Garschall; P. Klepsatel; G. Santos-Matos; E. Sucena et al. 

Microbiota-Derived Lactate Activates Production of Reactive Oxygen Species by the Intestinal NADPH Oxidase Nox and Shortens Drosophila Lifespan

I. Iatsenko; J-P. Boquete; B. Lemaitre; I. Iatsenko; J-P. Boquete et al. 

Common and unique strategies of male killing evolved in two distinct Drosophila symbionts

T. Harumoto; T. Fukatsu; B. Lemaitre 

In Vitro Culture of the Insect Endosymbiont Spiroplasma poulsonii Highlights Bacterial Genes Involved in Host-Symbiont Interaction

F. Masson; S. Calderon Copete; F. Schüpfer; G. Garcia-Arraez; B. Lemaitre et al. 

Cell-Specific Imd-NF-κB Responses Enable Simultaneous Antibacterial Immunity and Intestinal Epithelial Cell Shedding upon Bacterial Infection

Z. Zhai; J-P. Boquete; B. Lemaitre; Z. Zhai; J-P. Boquete et al. 

Male-killing toxin in a bacterial symbiont of Drosophila

T. Harumoto; B. Lemaitre 

Anatomy and Physiology of the Digestive Tract of Drosophila melanogaster

I. Miguel-Aliaga; H. Jasper; B. Lemaitre 

The double-edged toxins : how Spiroplasma Ribosome-Inactivating Proteins affect Drosophila melanogaster life history traits

The melanization reaction in Drosophila: More than black or white

La montée du narcissisme ?

A. Albertelli; B. Lemaitre 

Transforming Growth Factor beta/Activin signaling in neurons increases susceptibility to starvation

W-B. A. Chng; R. Koch; X. Li; S. Kondo; E. Nagoshi et al. 

Thioester-containing proteins regulate the Toll pathway and play a role in Drosophila defence against microbial pathogens and parasitoid wasps

A. Dostalova; S. Rommelaere; M. Poidevin; B. Lemaitre 

A genetic framework controlling the differentiation of intestinal stem cells during regeneration in Drosophila

Z. Zhai; J-P. Boquete; B. Lemaitre 

Protection from within

F. Masson; B. Lemaitre 

The gram-negative sensing receptor PGRP-LC contributes to grooming induction in Drosophila

A. Yanagawa; C. Neyen; B. Lemaitre; F. Marion-Poll 

Science, narcissism and the quest for visibility

B. Lemaitre 

Physiological Adaptations to Sugar Intake: New Paradigms from Drosophila melanogaster

W-B. A. Chng; V. Hietakangas; B. Lemaitre 

The Role of Lipid Competition for Endosymbiont-Mediated Protection against Parasitoid Wasps in Drosophila

J. C. Paredes; J. K. Herren; F. Schüpfer; B. Lemaitre 

Chemometric Analysis of Bacterial Peptidoglycan Reveals Atypical Modifications That Empower the Cell Wall against Predatory Enzymes and Fly Innate Immunity

A. Espaillat; O. Forsmo; K. El Biari; R. Björk; B. Lemaitre et al. 

Remote Control of Intestinal Stem Cell Activity by Haemocytes in Drosophila

S. Chakrabarti; J. P. Dudzic; X. Li; E. J. Collas; J-P. Boquete et al. 

The regulatory isoform rPGRP-LC induces immune resolution via endosomal degradation of receptors

C. Neyen; C. Runchel; F. Schüpfer; P. Meier; B. Lemaitre 

The dual oxidase gene BdDuox regulates the intestinal bacterial community homeostasis of Bactrocera dorsalis

Z. Yao; A. Wang; Y. Li; Z. Cai; B. Lemaitre et al. 

Male-killing symbiont damages host’s dosage-compensated sex chromosome to induce embryonic apoptosis

T. Harumoto; H. Anbutsu; B. Lemaitre; T. Fukatsu 

Cell Division by Longitudinal Scission in the Insect Endosymbiont

E. Ramond; C. Maclachlan; S. Clerc-Rosset; G. W. Knott; B. Lemaitre 

PGRP-SD, an Extracellular Pattern-Recognition Receptor, Enhances Peptidoglycan-Mediated Activation of the Drosophila Imd Pathway

I. Iatsenko; S. Kondo; D. Mengin-Lecreulx; B. Lemaitre 

Connecting the obesity and the narcissism epidemics

B. Lemaitre 

Sensing Gram-negative bacteria: a phylogenetic perspective

C. Neyen; B. Lemaitre 

The Drosophila gut response to infection : a systems approach

Accumulation of differentiating intestinal stem cell progenies drives tumorigenesis

Z. Zhai; S. Kondo; N. Ha; J-P. Boquete; M. Brunner et al. 

Infection Dynamics and Immune Response in a Newly Described Drosophila-Trypanosomatid Association

P. T. Hamilton; J. Votypka; A. Dostalova; V. Yurchenko; N. H. Bird et al. 

Genetic, molecular and physiological basis of variation in Drosophila gut immunocompetence

M. S. B. Sleiman; D. Osman; A. Massouras; A. A. Hoffmann; B. Lemaitre et al. 

Genome Sequence of the Drosophila melanogaster Male-Killing Spiroplasma Strain MSRO Endosymbiont

J. C. Paredes; J. K. Herren; F. Schuepfer; R. Marin; S. Claverol et al. 

The Black cells phenotype is caused by a point mutation in the Drosophila pro-phenoloxidase 1 gene that triggers melanization and hematopoietic defects

C. Neyen; O. Binggeli; P. Roversi; L. Bertin; M. B. Sleiman et al. 

The Nimrod transmembrane receptor Eater is required for hemocyte attachment to the sessile compartment in Drosophila melanogaster

A. J. Bretscher; V. Honti; O. Binggeli; O. Burri; M. Poidevin et al. 

From Embryo to Adult: Hematopoiesis along the Drosophila Life Cycle

E. Ramond; M. Meister; B. Lemaitre 

Determination of the structure of the O-antigen and the lipid A from the entomopathogenic bacterium Pseudomonas entomophila lipopolysaccharide along with its immunological properties

I. Speciale; I. Paciello; L. L. Fazio; L. Sturiale; A. Palmigiano et al. 

Gut physiology mediates a trade-off between adaptation to malnutrition and susceptibility to food-borne pathogens

R. K. Vijendravarma; S. Narasimha; S. Chakrabarti; A. Babin; S. Kolly et al. 

Drosophila innate immunity: regional and functional specialization of prophenoloxidases

J. P. Dudzic; S. Kondo; R. Ueda; C. M. Bergman; B. Lemaitre 

Different flavors of Toll guide olfaction

C. Neyen; B. Lemaitre 

X-ray and Cryo-electron Microscopy Structures of Monalysin Pore-forming Toxin Reveal Multimerization of the Pro-form

P. Leone; C. Bebeacua; O. Opota; C. Kellenberger; B. Klaholz et al. 

Redefining the metabolic landscape through TGF-beta/Activin signaling in Drosophila melanogaster

Methods to study Drosophila immunity

C. Neyen; A. J. Bretscher; O. Binggeli; B. Lemaitre 

Prophenoloxidase Activation Is Required for Survival to Microbial Infections in Drosophila

O. Binggeli; C. Neyen; M. Poidevin; B. Lemaitre 

Insect endosymbiont proliferation is limited by lipid availability

J. K. Herren; J. C. Paredes; F. Schuepfer; K. Arafah; P. Bulet et al. 

The Drosophila MAPK p38c Regulates Oxidative Stress and Lipid Homeostasis in the Intestine

S. Chakrabarti; M. Poidevin; B. Lemaitre 

Transforming Growth Factor beta/Activin Signaling Functions as a Sugar-Sensing Feedback Loop to Regulate Digestive Enzyme Expression

W-B. A. Chng; M. S. B. Sleiman; F. Schuepfer; B. Lemaitre 

Microbiota-Induced Changes in Drosophila melanogaster Host Gene Expression and Gut Morphology

N. A. Broderick; N. Buchon; B. Lemaitre 

The Effectual Hitchhiker : Mechanisms and Consequences of Interactions Between Endosymbiotic Spiroplasma and Host Drosophila

The useful gate-crasher : molecular interactions between Drosophila and Spiroplasma

Pseudomonas entomophila: A Versatile Bacterium with Entomopathogenic Properties

G. Dieppois; O. Opota; J. Lalucat; B. Lemaitre 

Functional Analysis of PGRP-LA in Drosophila Immunity

M. Gendrin; A. Zaidman-Remy; N. A. Broderick; J. Paredes; M. Poidevin et al. 

Crystallization and preliminary X-ray analysis of monalysin, a novel beta-pore-forming toxin from the entomopathogen Pseudomonas entomophila

M. Blemont; R. Vincentelli; C. Kellenberger; O. Opota; B. Lemaitre et al. 

dRYBP Contributes to the Negative Regulation of the Drosophila Imd Pathway

R. Aparicio; C. Neyen; B. Lemaitre; A. Busturia 

Morphological and Molecular Characterization of Adult Midgut Compartmentalization in Drosophila

N. Buchon; D. Osman; F. P. A. David; H. Y. Fang; J-P. Boquete et al. 

Vertical transmission of a Drosophila endosymbiont via cooption of the yolk transport and internalization machinery

J. K. Herren; J. C. Paredes; F. Schüpfer; B. Lemaitre 

Translation inhibition and metabolic stress pathways in the host response to bacterial pathogens

B. Lemaitre; S. E. Girardin 

The Digestive Tract of Drosophila melanogaster

B. Lemaitre; I. Miguel-Aliaga 

Gut homeostasis in a microbial world: insights from Drosophila melanogaster

N. Buchon; N. A. Broderick; B. Lemaitre 

Role and regulation of the melanization reaction in Drosophila immune response

The contribution of the host stress response to the pathogenesis of Pseudomonas entomophila in the Drosophila intestine

Autocrine and paracrine unpaired signalling regulate intestinal stem cell maintenance and division

D. Osman; N. Buchon; S. Chakrabarti; Y-T. Huang; W-C. Su et al. 

Insect-microbe interactions: the good, the bad and the others

J. Herren; B. Lemaitre 

Tissue- and ligand-specific sensing of gram-negative infection in drosophila by PGRP-LC isoforms and PGRP-LE

C. Neyen; M. Poidevin; A. Roussel; B. Lemaitre 

Gut-associated microbes of Drosophila melanogaster

N. A. Broderick; B. Lemaitre 

Taxonomic characterisation of Pseudomonas strain L48 and formal proposal of Pseudomonas entomophila sp nov.

M. Mulet; M. Gomila; B. Lemaitre; J. Lalucat; E. Garcia-Valdes 

Infection-induced host translational blockage inhibits immune responses and epithelial renewal in the Drosophila gut

S. Chakrabarti; P. Liehl; N. Buchon; B. Lemaitre 

The drosophila gut: A new paradigm for epithelial immune response

B. Lemaitre 

Distinguishing dead from alive – a novel intracellular receptor mediates ligand-specific regulation of Relish-dependent immune activation in Drosophila

C. Neyen; B. Lemaitre 

Monalysin, a novel ß-pore-forming toxin from the Drosophila pathogen Pseudomonas entomophila, contributes to host intestinal damage and lethality

O. Opota; I. Vallet-Gély; R. Vincentelli; C. Kellenberger; I. Iacovache et al. 

Negative Regulation by Amidase PGRPs Shapes the Drosophila Antibacterial Response and Protects the Fly from Innocuous Infection

J. C. Paredes; D. P. Welchman; M. Poidevin; B. Lemaitre 

Spiroplasma and host immunity: activation of humoral immune responses increases endosymbiont load and susceptibility to certain Gram-negative bacterial pathogens in Drosophila melanogaster

J. K. Herren; B. Lemaitre 

Genetic evidence for a protective role of the peritrophic matrix against intestinal bacterial infection in Drosophila melanogaster

T. Kuraishi; O. Binggeli; O. Opota; N. Buchon; B. Lemaitre 

Drosophila immunity: analysis of PGRP-SB1 expression, enzymatic activity and function

A. Zaidman-Rémy; M. Poidevin; M. Hervé; D. P. Welchman; J. C. Paredes et al. 

Mercury is a direct and potent γ-secretase inhibitor affecting Notch processing and development in Drosophila

J-R. Alattia; T. Kuraishi; M. Dimitrov; I. Chang; B. Lemaitre et al. 

A secondary metabolite acting as a signalling molecule controls Pseudomonas entomophila virulence

I. Vallet-Gely; O. Opota; A. Boniface; A. Novikov; B. Lemaitre 

Association of hemolytic activity of Pseudomonas entomophila, a versatile soil bacterium, with cyclic lipopeptide production

I. Vallet-Gely; A. Novikov; L. Augusto; P. Liehl; G. Bolbach et al. 

Drosophila EGFR pathway coordinates stem cell proliferation and gut remodeling following infection

N. Buchon; N. A. Broderick; T. Kuraishi; B. Lemaitre 

Toll-like receptors – an evolutionary perspective

B. Lemaitre 

Proteolytic cascade for the activation of the insect toll pathway induced by the fungal cell wall component

K-B. Roh; C-H. Kim; H. Lee; H-M. Kwon; J-W. Park et al. 

Long-range activation of systemic immunity through peptidoglycan diffusion in Drosophila

M. Gendrin; D. P. Welchman; M. Poidevin; M. Hervé; B. Lemaitre 

Drosophila intestinal response to bacterial infection: activation of host defense and stem cell proliferation

N. Buchon; N. A. Broderick; M. Poidevin; S. Pradervand; B. Lemaitre 

A single modular serine protease integrates signals from pattern-recognition receptors upstream of the Drosophila Toll pathway

N. Buchon; M. Poidevin; H-M. Kwon; A. Guillou; V. Sottas et al. 

Insect immunity: from pattern recognition to symbiont-mediated host defense

D. P. Welchman; S. Aksoy; F. Jiggins; B. Lemaitre 

A non-redundant role for Drosophila Mkk4 and hemipterous/Mkk7 in TAK1-mediated activation of JNK

P. Geuking; R. Narasimamurthy; B. Lemaitre; K. Basler; F. Leulier 

Invasive and indigenous microbiota impact intestinal stem cell activity through multiple pathways in Drosophila

N. Buchon; N. A. Broderick; S. Chakrabarti; B. Lemaitre 

Genetic ablation of Drosophila phagocytes reveals their contribution to both development and resistance to bacterial infection

A. Defaye; I. Evans; M. Crozatier; W. Wood; B. Lemaitre et al. 

Recognition and response to microbial infection in Drosophila

N. A. Broderick; B. Lemaitre 

A serpin that regulates immune melanization in the respiratory system of Drosophila

H. Tang; Z. Kambris; B. Lemaitre; C. Hashimoto 

Animal models for host-pathogen interactions

B. Lemaitre; F. M. Ausubel 

Drosophila immunity: methods for monitoring the activity of Toll and Imd signaling pathways

Y. Romeo; B. Lemaitre 

PIMS modulates immune tolerance by negatively regulating Drosophila innate immune signaling

N. Lhocine; P. S. Ribeiro; N. Buchon; A. Wepf; R. Wilson et al. 

Drosophila Serpin-28D regulates hemolymph phenoloxidase activity and adult pigmentation

C. Scherfer; H. Tang; Z. Kambris; N. Lhocine; C. Hashimoto et al. 

Evf, a virulence factor produced by the Drosophila pathogen Erwinia carotovora, is an S-palmitoylated protein with a new fold that binds to lipid vesicles

S. Quevillon-Cheruel; N. Leulliot; C. A. Muniz; M. Vincent; J. Gallay et al. 

Cyanogenesis in Pseudomonas entomophila: an entomopathogenic bacterium

B. Ryall; H. Nasser; B. Lemaitre; D. Mossialos; H. D. Williams 

Toll-like receptors–taking an evolutionary approach

F. Leulier; B. Lemaitre 

Bacterial strategies to overcome insect defences

I. Vallet-Gely; B. Lemaitre; F. Boccard 

The host defense of Drosophila melanogaster

B. Lemaitre; J. Hoffmann 

Complete genome sequence of the entomopathogenic and metabolically versatile soil bacterium Pseudomonas entomophila

N. Vodovar; D. Vallenet; S. Cruveiller; Z. Rouy; V. Barbe et al. 

Two proteases defining a melanization cascade in the immune system of Drosophila

H. Tang; Z. Kambris; B. Lemaitre; C. Hashimoto 

Insect immunity: the post-genomic era

J. Bangham; F. Jiggins; B. Lemaitre 

Drosophila immunity: a large-scale in vivo RNAi screen identifies five serine proteases required for Toll activation

Z. Kambris; S. Brun; I-H. Jang; H-J. Nam; Y. Romeo et al. 

Erwinia carotovora Evf antagonizes the elimination of bacteria in the gut of Drosophila larvae

C. Acosta Muniz; D. Jaillard; B. Lemaitre; F. Boccard 

The Drosophila inhibitor of apoptosis protein DIAP2 functions in innate immunity and is essential to resist gram-negative bacterial infection

F. Leulier; N. Lhocine; B. Lemaitre; P. Meier 

Prevalence of local immune response against oral infection in a Drosophila/Pseudomonas infection model

P. Liehl; M. Blight; N. Vodovar; F. Boccard; B. Lemaitre 

The Toll immune-regulated Drosophila protein Fondue is involved in hemolymph clotting and puparium formation

C. Scherfer; M. R. Qazi; K. Takahashi; R. Ueda; M. S. Dushay et al. 

A Spätzle-processing enzyme required for toll signaling activation in Drosophila innate immunity

I-H. Jang; N. Chosa; S-H. Kim; H-J. Nam; B. Lemaitre et al. 

The Drosophila amidase PGRP-LB modulates the immune response to bacterial infection

A. Zaidman-Rémy; M. Hervé; M. Poidevin; S. Pili-Floury; M-S. Kim et al. 

The MAPKKK Mekk1 regulates the expression of Turandot stress genes in response to septic injury in Drosophila

S. Brun; S. Vidal; P. Spellman; K. Takahashi; H. Tricoire et al. 

Inhibitor of apoptosis 2 and TAK1-binding protein are components of the Drosophila Imd pathway

A. Kleino; S. Valanne; J. Ulvila; J. Kallio; H. Myllymäki et al. 

Drosophila host defense after oral infection by an entomopathogenic Pseudomonas species

N. Vodovar; M. Vinals; P. Liehl; A. Basset; J. Degrouard et al. 

Structure and metabolism of peptidoglycan and molecular requirements allowing its detection by the Drosophila innate immune system

D. Mengin-Lecreulx; B. Lemaitre 

The road to Toll

B. Lemaitre 

A Drosophila pattern recognition receptor contains a peptidoglycan docking groove and unusual L,D-carboxypeptidase activity

C-I. Chang; S. Pili-Floury; M. Hervé; C. Parquet; Y. Chelliah et al. 

In vivo RNA interference analysis reveals an unexpected role for GNBP1 in the defense against Gram-positive bacterial infection in Drosophila adults

S. Pili-Floury; F. Leulier; K. Takahashi; K. Saigo; E. Samain et al. 

Peptidoglycan molecular requirements allowing detection by the Drosophila immune deficiency pathway

C. R. Stenbak; J-H. Ryu; F. Leulier; S. Pili-Floury; C. Parquet et al. 

Drosophila: a polyvalent model to decipher host-pathogen interactions

N. Vodovar; C. Acosta; B. Lemaitre; F. Boccard 

The Drosophila immune system detects bacteria through specific peptidoglycan recognition

F. Leulier; C. Parquet; S. Pili-Floury; J-H. Ryu; M. Caroff et al. 

Directed expression of the HIV-1 accessory protein Vpu in Drosophila fat-body cells inhibits Toll-dependent immune responses

F. Leulier; C. Marchal; I. Miletich; B. Limbourg-Bouchon; R. Benarous et al. 

Sensing microbes by diverse hosts. Workshop on pattern recognition proteins and receptors.

S. E. Girardin; D. J. Philpott; B. Lemaitre 

A single gene that promotes interaction of a phytopathogenic bacterium with its insect vector, Drosophila melanogaster

A. Basset; P. Tzou; B. Lemaitre; F. Boccard 

A ubiquitin-proteasome pathway represses the Drosophila immune deficiency signaling cascade

R. S. Khush; W. D. Cornwell; J. N. Uram; B. Lemaitre 

27 Methods for studying infection and immunity in Drosophila

P. Tzou; M. Meister; B. Lemaitre 

An immune-responsive Serpin regulates the melanization cascade in Drosophila

E. De Gregorio; S-J. Han; W-J. Lee; M-J. Baek; T. Osaki et al. 

The Toll and Imd pathways are the major regulators of the immune response in Drosophila

E. De Gregorio; P. T. Spellman; P. Tzou; G. M. Rubin; B. Lemaitre 

Inducible expression of double-stranded RNA reveals a role for dFADD in the regulation of the antibacterial response in Drosophila adults

F. Leulier; S. Vidal; K. Saigo; R. Ueda; B. Lemaitre 

The mosquito genome: the post-genomic era opens

E. De Gregorio; B. Lemaitre 

Immunology. Pathogen surveillance–the flies have it.

R. S. Khush; F. Leulier; B. Lemaitre 

Constitutive expression of a single antimicrobial peptide can restore wild-type resistance to infection in immunodeficient Drosophila mutants

P. Tzou; J-M. Reichhart; B. Lemaitre 

How Drosophila combats microbial infection: a model to study innate immunity and host-pathogen interactions

P. Tzou; E. De Gregorio; B. Lemaitre 

Genome-wide analysis of the Drosophila immune response by using oligonucleotide microarrays

E. De Gregorio; P. T. Spellman; G. M. Rubin; B. Lemaitre 

Drosophila immunity: two paths to NF-kappaB

R. S. Khush; F. Leulier; B. Lemaitre 

Mutations in the Drosophila dTAK1 gene reveal a conserved function for MAPKKKs in the control of rel/NF-kappaB-dependent innate immune responses

S. Vidal; R. S. Khush; F. Leulier; P. Tzou; M. Nakamura et al. 

Gram-negative bacteria-binding protein, a pattern recognition receptor for lipopolysaccharide and beta-1,3-glucan that mediates the signaling for the induction of innate immune genes in Drosophila melanogaster cells

Y. S. Kim; J. H. Ryu; S. J. Han; K. H. Choi; K. B. Nam et al. 

The Drosophila caspase Dredd is required to resist gram-negative bacterial infection

F. Leulier; A. Rodriguez; R. S. Khush; J. M. Abrams; B. Lemaitre 

Comparative genomics of the eukaryotes

G. M. Rubin; M. D. Yandell; J. R. Wortman; G. L. Gabor Miklos; C. R. Nelson et al. 

Tissue-specific inducible expression of antimicrobial peptide genes in Drosophila surface epithelia

P. Tzou; S. Ohresser; D. Ferrandon; M. Capovilla; J. M. Reichhart et al. 

The phytopathogenic bacteria Erwinia carotovora infects Drosophila and activates an immune response

A. Basset; R. S. Khush; A. Braun; L. Gardan; F. Boccard et al. 

Stop press: genes that fight infections: what the drosophila genome says about animal immunity

R. Khush; B. Lemaitre 

Le génome de la mouche du vinaigre

B. Lemaitre 

Genes that fight infection: what the Drosophila genome says about animal immunity

R. S. Khush; B. Lemaitre 

A mosaic analysis in Drosophila fat body cells of the control of antimicrobial peptide genes by the Rel proteins Dorsal and DIF

P. Manfruelli; J. M. Reichhart; R. Steward; J. A. Hoffmann; B. Lemaitre 

La drosophile : un modèle pour l’étude de la réponse immunitaire innée

B. Lemaitre 

Two distinct pathways can control expression of the gene encoding the Drosophila antimicrobial peptide metchnikowin

E. A. Levashina; S. Ohresser; B. Lemaitre; J. L. Imler 

In vivo regulation of the IkappaB homologue cactus during the immune response of Drosophila

E. Nicolas; J. M. Reichhart; J. A. Hoffmann; B. Lemaitre 

A drosomycin-GFP reporter transgene reveals a local immune response in Drosophila that is not dependent on the Toll pathway

D. Ferrandon; A. C. Jung; M. Criqui; B. Lemaitre; S. Uttenweiler-Joseph et al. 

Drosophila host defense: differential induction of antimicrobial peptide genes after infection by various classes of microorganisms

B. Lemaitre; J. M. Reichhart; J. A. Hoffmann 

Drosophila immunity: analysis of larval hemocytes by P-element-mediated enhancer trap

A. Braun; B. Lemaitre; R. Lanot; D. Zachary; M. Meister 

Antimicrobial peptide defense in Drosophila

M. Meister; B. Lemaitre; J. A. Hoffmann 

Expression of antimicrobial peptide genes after infection by parasitoid wasps in Drosophila

E. Nicolas; A. J. Nappi; B. Lemaitre 

The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults

B. Lemaitre; E. Nicolas; L. Michaut; J. M. Reichhart; J. A. Hoffmann 

A recessive mutation, immune deficiency (imd), defines two distinct control pathways in the Drosophila host defense

B. Lemaitre; E. Kromer-Metzger; L. Michaut; E. Nicolas; M. Meister et al. 

Functional analysis and regulation of nuclear import of dorsal during the immune response in Drosophila

B. Lemaitre; M. Meister; S. Govind; P. Georgel; R. Steward et al. 

Drosophila P element: transposition, regulation and evolution

D. Coen; B. Lemaitre; M. Delattre; H. Quesneville; S. Ronsseray et al. 

Maternal repression of the P element promoter in the germline of Drosophila melanogaster: a model for the P cytotype

B. Lemaitre; S. Ronsseray; D. Coen 

Maternal inheritance of P cytotype in Drosophila melanogaster: a “pre-P cytotype” is strictly extra-chromosomally transmitted

S. Ronsseray; B. Lemaitre; D. Coen 

Expression and nuclear translocation of the rel/NF-kappa B-related morphogen dorsal during the immune response of Drosophila

J. M. Reichhart; P. Georgel; M. Meister; B. Lemaitre; C. Kappler et al. 

Insect immunity: the diptericin promoter contains multiple functional regulatory sequences homologous to mammalian acute-phase response elements

P. Georgel; M. Meister; C. Kappler; B. Lemaitre; J. M. Reichhart et al. 

L’element P de drosophila melanogaster : mecanismes controlant la transposition

P regulatory products repress in vivo the P promoter activity in P-lacZ fusion genes

B. Lemaitre; D. Coen