Subcellular composition and transcriptome of human lungs suffering from tuberculosis (TB)

Description of the internship

In collaboration with our partners in Tbilisi, Georgia, we have established a cohort of patients suffering from severe tuberculosis who underwent resection of infected lung material.
We aim to characterize the resected material histologically and through gene expression using advanced imaging technologies (multiplexed immunofluorescence, artificial intelligence-guided image analysis) to identify new disease biomarkers and pathways.

Required qualities and skills

  • Great interest in the subject and strong motivation to learn molecular biology and immunohistological techniques
  • Ideally, initial work experience in a natural sciences laboratory and openness to learning R programming

Duration of internship: 3 to 6 months
Location: 23845 Borstel, Schleswig-Holstein, Germany
Accomodation provided: Yes
Meals provided: No 

Section(s) concerned: SV

Description of the organization

The Research Center Borstel (RCB) conducts biomedical research on pulmonary diseases. One of its pillars is dedicated to tuberculosis (TB) and is equipped with a BSL 3 laboratory and a clinic specialized in tuberculosis. The RCB is integrated into the multidisciplinary Leibniz Association at the German level.

Name: Research Center Borstel
Contact person: Dr. Tobias Dallenga, [email protected]