A type 2 cytokine Fc–IL-4 revitalizes exhausted CD8+ T cells against cancer

Feng, B. ^# ; Bai, Z. ^# ; Zhou, X. ; Zhao, Y. ; Xie, Y.-Q. ; Huang, X. ; Liu, Y. ; Enbar, T. ; Li, R. ; Wang, Y. ; Gao, M. ; Bonati, L.; Peng, M.-W.; Li, W.; Tao, B.; Charmo, M.; Held, W.; Melenhorst, J.J. ; Fan, R. * ; Guo, Y. * ; Tang, L. *

Nature 2024a, in press.

Single-cell CAR T atlas reveals type2 function in 8-year leukemia remission

Bai, Z. ^# ; Feng, B. ^# ; McClory, S.E. ; de Oliveira, B.C. ; Diorio, C. ; Tao, B. ; Yang, L. ; Zhao, Z. ; Peng, L. ; Sferruzza, G. ; Zhou, L. ; Kerr, J. ; Baysoy, A. ; Su, G. ; Zhou, X. ; Camara, P.G. ; Chen, S. ; Tang, L. * ; June, C.H. * ; Melenhorst J.J. * ; Grupp, S.A. * ; Fan, R. *

Nature 2024b, in press.

Research Briefing: IL-10-producing CAR T cells efficiently clear solid tumors

Sun, J. * ; Tang, L. *

Nat. Biotech. 2024, in press.

IL-10-expressing CAR-T cells resist dysfunction and mediate durable clearance of solid tumors and metastases

Zhao, Y. ^# ; Chen, J. ^# ; Andreatta, M. ; Feng, B. ; Xie, Y.-Q. ; Wenes, M. ; Wang, Y. ; Gao, M. ; Hu, X. ; Romero, P. ; Carmona, S. ; Sun, J. * ; Guo, Y. * ; Tang, L. *

Nat. Biotech. 2024, in press.

Evidence and therapeutic implications of biomechanically regulated immunosurveillance in cancer and other diseases

Mittelheisser, V. ^# ; Gensbittel, V. ^# ; Bonati, L. ^# ; Li, W. ^# ; Tang, L. * ; Goetz, J.G. *

Nat. Nanotech. 2024, 19, 281-297. 

A redox-responsive prodrug for tumor-targeted glutamine restriction

Prange, C.J. ; Ben Sayed, N.Y. ; Feng, B. ; Goepfert, C. ; Trujillo, D.O. ; Hu, X. ; Tang, L. *

J. Control Release 2024, 368, 251-264.

Smart chemistry for traceless release of anticancer therapeutics

Prange, C.J. ; Hu, X. ; Tang, L. *

Biomaterials 2023, 303, 122353.

Rational design of chemically controlled antibodies and protein therapeutics

Marchand, A. ^# ; Bonati, L. ^# ; Shui, S. ; Scheller, L. ; Gainza, P. ; Rosset, S. ; Rosset, S. ; Georgeon, S. ; Tang, L. * ; Bruno E. Correia *

ACS Chem. Biol. 2023, 18, 1259-1265.

Soft Cancer Cells Squeeze Through T cell’s Grip

Wang, Y. ; Kurum, A. ; Tang, L. *

Matter 2022, 5, 2510-2513.

Microfluidic T Cell Selection by Cellular Avidity

Ashby, J.F. ; Schmidt, J. ; Magnus, NKC ; Kurum, A. ; Koch, C. ; Harari, A ; Tang, L. ; Au, S.H.

Adv. Healthcare Mater. 2022, 2200169.

BCG Hydrogel Promotes CTSS-Mediated Antigen Processing and Presentation, Thereby Suppressing Metastasis and Prolonging Survival in Melanoma

Kremenovic, M. ; Chan, A.A. ; Feng, B. ; Bäriswyl, L. ; Robatel, S. ; Gruber, T. ; Tang, L. ; Lee, D.J. ; Schenk, M.

J. ImmunoTher. Cancer. 2022, 10, e004133.

Cancer-Cell Stiffening via Cholesterol Depletion Enhances Adoptive T-cell Therapy

Lei, K. ; Kurum, A. ; Kaynak, M. ; Bonati, L. ; Han, Y. ; Cencen, V. ; Gao, M. ; Xie, Y.-Q. ; Guo, Y. ; Hannebelle, M.T.M. ; Wu, Y. ; Zhou, G, ; Guo, M. ; Fantner, G.E. ; Sakar, M.S. ; Tang, L.*

Nature Biomedical Engineering 2021, 5, 1411-1425. Full-text available. Highlighted by Editorial of Nature Biomedical Eningeering, Volume 5 Issue 12, December 2021.

Highlighted:  EPFL News ; RTS ; Le Matin ; Medical Press

Delivery of STING agonists for adjuvanting subunit vaccines

Van Herck, S. ; Feng, B. ; Tang, L.*

Advanced Drug Delivery Reviews 2021, 179, 114020.

Switchable Immune Modulator for Tumor-Specific Activation of Anticancer Immunity

Zhao, Y. ; Xie, Y.-Q. ; Van Herck, S. ; Nassiri, S. ; Gao, M. ; Guo, Y. ; Tang, L.*

Science Advances 2021, 7, eabg7291.

Highlighted:  EPFL News ; RCI-Radio Canada ; Mirage News ; Medical Press

A Manganese Phosphate Nanocluster Activates the cGAS-STING Pathway for Enhanced Cancer Immunotherapy

Gao, M. ; Xie, Y.-Q. ; Lei, K. ; Zhao, Y. ; Kurum, A. ; Van Herck, S. ; Guo, Y. ; Hu, X. ; Tang, L.*

Advanced Therapeutics 2021, 4, 2100065.

Metabolic Reprogramming of Terminally Exhausted CD8+ T cells by IL-10 Enhances Anti-Tumor Immunity

Guo, Y.^# ; Xie, Y.-Q.^# ; Gao, M. ; Zhao, Y. ; Franco, F. ; Wenses, M. ; Siddiqui, I. ; Bevilacqua, A. ; Wang, H. ; Yang, H. ; Feng, B. ; Xie, X. ; Sabatel, C.M. ; Tschumi, B. ; Chaiboonchoe, A. ; Wang, Y. ; Li, W. ; Xiao, W. ; Held, W. ; Romero, P. ; Ho, P.-C.* ; Tang, L.*

Nature Immunology 2021, 22, 746-756. Full-text available. Cover story of Nature Immunology, Volume 22 Issue 6, June 2021.

Highlighted: EPFL News ; RTS ; ACIR ; Nature middle east

Cytokine Engineering for Targeted Cancer Immunotherapy

Bonati, Lucia ; Tang, L.*

Current Opinion in Chemical Biology 2021, 62, 43-52.

T cell force-responsive delivery of anticancer drugs using mesoporous silica microparticles

Kewen, Lei^# ; Tang, L.*

Materials Horizons 2020, 7, 3196-3200. Cover story of Materials Horizons Issue 12, December.

Highlighted:  EPFL News; Materials Horizons Emerging Investigator Series.

Mechanical Immunoengineering of T cells for Therapeutic Applications

Kewen, Lei ; Armand, Kurum ; Tang, L.*

Accounts of Chemical Research 2020, 53, 12, 2777–2790.

Central memory CD8+ T cells derive from stem-like Tcf7hi effector cells in the absence of cytotoxic differentiation

Ferreira, D.P. ; Silva, J.G. ; Wyss, T. ; Maas, R. ; Scarpellino, L. ; Marraco, S.A.F. ; Tang, Li ; Delorenzi, M. ; Speiser, D.E. ; Held, W.

Immunity 2020, 53, 5, 985-1000.

Disturbed mitochondrial dynamics in CD8+ TILs reinforce T cell exhaustion

Yu, Y.R. ; Imrichova, Hana ; Chao, Tung ; Xiao, Zhengtao ; Gao, Min ; Rincon-Restrepo, Marcela ; Franco, Fabien ; Genolet, Raphael ; Cheng, Wan-Chen ; Jandus, Camilla ; Coukos, George ; Jiang, Yi-Fan ; Locasale, Jason W. ; Zippelius, Alfred ; Liu, Pu-Ste ; Tang, L.; Bock, Christoph ; Vannini, Nicola &amp ; Ho, Ping-Chih.

Nature Immunology 2020, 21, 1540–1551.

Redox-Responsive Polycondensate Neoepitope for Enhanced Personalized Cancer Vaccine

Wei, L.^# ; Zhao, Y.^# ; Hu, X. ; Tang, L.*

ACS Central Science 2020, 6, 3, 404–412.

Highlighted:  EPFL News

Synthetic 3D scaffolds for cancer immunotherapy

Kurum, A. ; Gao, M. ; Tang, L.*

Curr. Opin. Biotechnol. 2020, 65, 1-8.

Regulatory T Cells Engineered with TCR-Signaling-Responsive IL-2 Nanogels Suppress Alloimmunity in Sites of Antigen Encounter

Eskandari, S.K. ; Sulkaj, I. ; Melo, M.B. ; Li, N. ; Allos, H. ; Kollar, B. ; Borges, T.J. ; Eskandari, A.S. ; Cai, S. ; Assaker, J.P. ; Choi, J.Y. ; Al Dulaijan, B.S. ; Mansouri, A. ; Haik, Y. ; Leuvenink, H.G.D. ; van Son, W.J. ; Pomahac, B. ; Riella, L.V. ; Tang, L. ; Seelen, M.A.J. ; Irvine, D.J. & Azzi, J.R.

Science Translational Medicine 2020, 12, eaaw4744.

Donor-Cell Engineering with GSK3 Inhibitor-Loaded Nanoparticles Enhances Engraftment Following in Utero Transplantation

Loukogeorgakis, S.P. ; Fachin, C.G. ; Dias, A.S. ; Li, H. ; Tang, L. ; im, A.G. ; Vrecenak, J.D. ; Stratigis, J. ; Ahn, N.J. ; Nissim, I. ; Nissim, I. ; Moron, A.F. ; Martins, J.L. ; Peranteau, W.H. ; Coppi, P.D. ; Irvine, D.L. ; Flake, A.W.

Blood 2019, 34 (22): 1983–1995.

A Magnetic Nanovaccine Enhances Cancer Immunotherapy

Guo, Y. ; Tang, L.*

ACS Central Science 2019, 5, 747-749. DOI: 10.1021/acscentsci.9b00325.

Redox-Responsive Interleukin-2 Nanogel Specifically and Safely Promotes the Proliferation and Memory Precursor Differentiation of Tumor-Reactive T-Cells

Xie, Y-Q. ; Arik, H. ; Wei, L. ; Zheng, Y. ; Suh, H. ; Irvine, D.J. ; Tang, L.*

Biomaterials Science 2019, 7, 1345-1357. DOI: 10.1039/c8bm01556b. Invited contribution as Biomaterials Science Emerging Investigator

Surgery-free injectable macroscale biomaterials for local cancer immunotherapy

Lei, K. ; Tang, L.*

Biomaterials Science 2019, 7, 733-749. DOI : 10.1039/c8bm01470a. Invited review.

Engineering Cancer Vaccines Using Stimuli-Responsive Biomaterials

Zhao, Y. ; Guo, Y. ; Tang, L.*

Nano Research 2018, 11, 5355–5371. DOI : 10.1007/s12274-018-2162-1. Invited review. Special issue: 2018 Nano Research Young Innovators (NR45) Award in nanobiotechnology

Enhancing T-cell Therapy Through TCR Signaling-Responsive Nanoparticle Drug Delivery

Tang, L.* ; Zheng, Y. ; Melo, M.B. ; Mabardi, L. ; Castaño, A.P. ; Xie, Y.-Q. ; Li, N. ; Kudchodkar, S.B. ; Wong, H.C. ; Jeng, E.K. ; Maus, M.V. and Irvine, D.J.*

Nature Biotechnology 2018, 36, 707-716. DOI : 10.1038/nbt.4181. Cover story of Nature Biotechnology, Volume 36 Issue 8, August 2018. News & Views “A backpack revs up T-cell activity” in Nat. Biotech. 

Highlighted: MIT News, EPFL News, EurekAlert!, Phys.org, Nanowerk, My Science, eCancer, Health Canal, Medindia, Madrid, UPI.com, Science and Enterprise, Brinkwire, Sina, BioArt

Neoantigen Vaccine Delivery for Personalized Anticancer Immunotherapy

Guo, Y. ; Lei, K. ; Tang, L.*

Frontiers in Immunology 2018, 9, 1499. DOI : 10.3389/fimmu.2018.01499. Invited review, total views 24,392.

Albumin as a “Trojan Horse” for polymeric nanoconjugate transendothelial transport across tumor vasculatures for improved cancer targeting

Yin, Q. ; Tang, L. ; Cai, K. ; Yang, X. ; Yin, L. ; Zhang, Y. ; Dobrucki, L.W. ; Helferich, W.G. ; Fan, T.M. and Cheng, J.

Biomaterials Science 2018, 6, 1189-1200. DOI : 10.1039/c8bm00149a.

Immunoengineering with Biomaterials for Enhanced Cancer Immunotherapy

Xie, Y-Q. ; Wei, L. ; Tang, L.*

WIREs Nanomed. Nanobiotechnol. 2018, 10, e1506. DOI : 10.1002/wnan.1506. Invited review.

Enhancing Adoptive Cell Therapy of Cancer through Targeted Delivery of Small-Molecule Immunomodulators to Internalizing or Noninternalizing Receptors

Zheng, Y. ; Tang, L.; Sudha Kumari, S.; and Irvine, D.J.

ACS Nano 2017, 11, 3089-3100. DOI : 10.1021/acsnano.7b00078.

High-Throughput Quantitation of Inorganic Nanoparticle Biodistribution at the Single-Cell Level Using Mass Cytometry

Yang, Y.S. ; Atukorale, P. ; Moynihan, K. ; Bekdemir, A. ; Rakhra, K. ; Tang, L.; Stellacci, F. and Irvine, D.J.

Nature Communications 2017, 8, 14069. DOI : 10.1038/ncomms14069.

Selective in vivo Metabolic Cell-Labeling-Mediated Cancer Targeting

Wang, H. ; Wang, R. ; Cai, K. ; He, H. ; Liu, Y. ; Yen, J. ; Wang, Z. ; Xu, M. ; Sun, Y. ; Zhou, X. ; Yin, Q. ; Tang, L.; Dobrucki, I.T. ; Dobrucki, L.W. ; Chaney, E.J. ; Boppart, S.A. ; Fan, T.M. ; Lezmi, S. ; Chen, X. ; Yin, L. ; Cheng, J.

Nature Chemical Biology 2017, 13, 415-424. DOI : 10.1038/nchembio.2297.

Pamidronate Functionalized Nanoconjugates for Targeted Therapy of Focal Skeletal Malignant Osteolysis

Yin, Q.^# ; Tang, L.^#; Tong, R. ; Sternberg, R. ; Yang, X. ; Dobrucki, L.W. ; Borst, L.B. ; Kamstock, D.A. ; Cai, K. ; Song, Z. ; Helferich, W.G. ; Cheng, J. and Fan T.M.

Proc. Natl. Acad. Sci. 2016, 113, E4601-4609. DOI : 10.1073/pnas.1603316113. 

Highlighted: NIH Director’ Blog, FierceBiotech, Noodles, EurekAlert!, Technology.org, Nanotechnology Now, Drug Discovery & Development, Bioscience technology, Azonano, Science Daily, Laboratory Journal, Phys.org, Nanowerk, Engineering at Illinois.

In Vivo Targeting of Metabolically Labeled Cancers with Ultra-Small Silica Nanoconjugates

Wang, H. ; Tang, L. ; Liu, Y. ; Dobrucka, I.T. ; Dobrucki, L.W. ; Yin, L. and Cheng, J.

Theranostics 2016, 6, 1467-1476. DOI : 10.7150/thno.16003.

Targeted Delivery of Immunomodulators to Lymph Nodes

Azzi, J. ; Yin, Q. ; Uehara, M. ; Ohori, S. ; Tang, L. ; Cai, K. ; Ichimura, T. ; McGrath, M. ; Maarouf, O. ; Kefaloyianni, E. ; Loughhead, S. ; Petr, J. ; Sun, Q. ; Kwon, M. ; Tullius, S. ; von Andrian, U.H. ; Cheng, J. and Abdi, R.

Cell Reports 2016, 15, 1202-1213. DOI : 10.1016/j.celrep.2016.04.007.

Targeting Tumor Vasculature with Aptamer Functionalized Doxorubicin-Polylactide Nanoconjugates for Enhanced Cancer Therapy

Tang, L. ; Coyle, V.J. ; Tong, R. ; Yin, Q. ; Pondenis, H. ; Shor, S. ; Borst, L. ; Cheng, J. ; Fan T.M.

ACS Nano 2015, 9, 5072-5081. DOI : 10.1021/acsnano.5b00166.

Biomaterial Strategies for Immunomodulation

Hotaling, N.A.^# ; Tang, L.^#; Irvine, D.J. ; Babensee, J.E.

Annu. Rev. Biomed. Eng. 2015, 17, 317-349. DOI : 10.1146/annurev-bioeng-071813-104814.

Bioorthogonal Oxime Ligation Mediated In Vivo Cancer Targeting

Tang, L.^# ; Yin, Q.^# ; Xu, Y. ; Zhou, Q. ; Cai, K. ; Yen, J. ; Dobrucki, L.W. and Cheng, J.

Chemical Science 2015, 6, 2182-2186. DOI : 10.1039/C5SC00063G.

Investigating the Optimal Size of Anticancer Nanomedicine

Tang, L. ; Yang, X. ; Yin, Q. ; Cai, K. ; Wang, H. ; Chaudhury, I. ; Yao, C. ; Zhou, Q. ; Kwon, M. ; Hartman, J.A. ; Dobrucki, L.W. ; Dobrucki, I.T. ; Borst, L.B. ; Lezmi, S. ; Helferich, W.G. ; Ferguson, A.L. ; Fan, T.M. and Cheng, J.

Proc. Natl. Acad. Sci. 2014, 111, 15344-15349. DOI : 10.1073/pnas.1411499111. Highlighted: Engineering at Illinois, Nanowerk, MedicalXpress, Science Daily, Nanotechnology Now, Daily News, EurekAlert!, Azonano, Health Canal, Bionity, Controlled Environments, Technology Org., Nature Science-Business eXchange 7(43); doi:10.1038/scibx.2014.1275.

Smart Chemistry in Polymeric Nanomedicines

Tong, R. ; Tang, L. ; Ma, L. ; Tu, C. ; Baumgartner, R. and Cheng, J.

Chem. Soc. Rev. 2014, 43, 6982-7012. DOI : 10.1039/C4CS00133H.

Nonporous Silica Nanoparticles for Nanomedicine Applications

Tang, L. ; Cheng, J.

Nano Today 2013, 8, 290-312. DOI : 10.1016/j.nantod.2013.04.007.

Size-Dependent Tumor Penetration and In Vivo Efficacy of Monodisperse Drug-silica Nanoconjugates

Tang, L. ; Gabrielson, N.P. ; Uckun, F. M. ; Fan, T.M. and Cheng, J.

Mol. Pharm. 2013, 10, 883-892. DOI : 10.1021/mp300684a.

Selective Delivery of an Anticancer Drug with Aptamer-Functionalized Liposomes to Breast Cancer Cells in Vitro and in Vivo.

Xing, H.^# ; Tang, L.^# ; Yang, X.^# ; Hwang, K. ; Wang, W. ; Yin, Q. ; Dobrucki, W.L. ; Yasui, N. ; Katzenellenbogen, J.A. ; Helferich, W.G. ; Cheng, J. and Lu, Y.

J. Mater. Chem. B. 2013, 1, 5288-5297. DOI : 10.1039/C3TB20412J.

Redox-Responsive, Core-Cross-Linked Micelles Capable of On-Demand, Concurrent Drug Release and Structure Disassembly

Wang, H. ; Tang, L. ; Tu, C. ; Song, Z. ; Yin, Q. ; Yin, L. ; Zhang, Z. ; Cheng, J.

Biomacromolecules 2013, 14, 3706-3712. DOI : 10.1021/bm401086d.

Chain-Shattering Polymeric Therapeutics with On-Demand Drug-Release Capability

Zhang, Y. ; Yin, Q. ; Yin, L. ; Ma, L. ; Tang, L. ; Cheng, J.

Angew. Chem. Int. Ed. 2013, 52, 6435-6439. DOI : 10.1002/anie.201300497.

Aptamer-Functionalized, Ultra-Small, Monodisperse Silica Nanoconjugates for Targeted Dual-Modal Imaging of Lymph Nodes with Metastatic Tumors

Tang, L. ; Yang, X. ; Dobrucki, W.L. ; Chaudhury, I. ; Yin, Q. ; Yao, C. ; Lezmi, S. ; Helferich, W.G. ; Fan, T.M. and Cheng, J.

Angew. Chem. Int. Ed. 2015, 51, 12721-12726. DOI : 10.1002/anie.201205271. Highlighted: Nature Science-Business eXchange 5(45); doi:10.1038/scibx.2012.1193.

Synthesis and Biological Response of Size-Specific, Monodisperse Drug-Silica Nanoconjugates

Tang, L. ; Fan, T.M. ; Borst, L.B. and Cheng, J.

ACS Nano 2012, 6, 3954-3966. DOI : 10.1021/nn300149c

Immunosuppressive Activity of Size-Controlled PEG-PLGA Nanoparticles Containing Encapsulated Cyclosporine A

Tang, L. ; Azzi, J. ; Kwon, M. ; Mounayar, M. ; Tong, R. ; Yin, Q. ; Moore, R. ; Skartsis, N. ; Fan, T.M. ; Abdi, R. ; Cheng, J.

J. Transplant. 2012, Article ID 896141. DOI :10.1155/2012/896141.

Targeting Mantle Cell Lymphoma with Anti-SYK Nanoparticles

Cely, I. ; Yiv, S. ; Yin, Q. ; Shahidzadeh, A. ; Tang, L. ; Cheng, J.

J. Analy. Oncol. 2012, 1, 1-9. DOI : 10.6000/1927-7229.2012.01.01.1.

The Therapeutic Efficacy of Camptothecin-Encapsulated Supramolecular Nanoparticles

Chen, K.J.^# ; Tang, L.^# ; Garcia, M.A. ; Wang, H. ; Lu, H. ; Lin, W.Y. ; Hou, S. ; Yin., Q. ; Shen, C.K.F. ; Cheng, J. ; Tseng, H.R.

Biomaterials 2011, 33, 1162-1169. DOI : 10.1016/j.biomaterials.2011.10.044.

Translocation of HIV TAT Peptide and Analogues Induced by Multiplexed Membrane and Cytoskeletal Interactions

Mishra, A. ; Lai, G.H. ; Schmidt, N.W. ; Sun, V.Z. ; Rodriguez, A.R. ; Tong, R. ; Tang, L. ; Cheng, J. ; Deming, T.J. ; Kamei, D.T. ; Wong, G.C.L.

Proc. Natl. Acad. Sci. 2011, 108, 16883-16888. DOI : 10.1073/pnas.1108795108.

Polylactide-Cyclosporin A Nanoparticles for Targeted Immunosuppression

Azzi, J.^# ; Tang, L.^# ; Moore, R. ; Tong, R. ; El, Haddad N. ; Akiyoshi, T. ; Mfarrej, B. ; Yang, S. ; Jurewicz, M. ; Ichimura, T. ; Lindeman, N. ; Cheng, J. ; Abdi, R.

FASEB J. 2010, 24, 3927-3938. DOI : 10.1096/fj.10-154690.

Lymphatic Biodistribution of Polylactide Nanoparticles

Chaney, E. J. ; Tang, L. ; Tong, R. ; Rezaeipoor, R. ; Cheng, J. ; Boppart, S.

Mol. Imag. 2010, 9, 153-162.

Polylactide Nanoparticles Containing Stably-Incorporated Cyanine Dyes for In Vitro and In Vivo Imaging Applications

Tong, R. ; Coyle, V.J ; Tang, L. ; Barger, A.M. ; Fan, T.M. ; Cheng, J.

Microsc. Res. Tech. 2010, 73, 901-909. DOI : 10.1002/jemt.20824.

Nanopolymeric Therapeutics

Tong, R. ; Christian, D.A. ; Tang, L. ; Cabral, H. ; Baker, J.R. Jr. ; Kataoka, K. ; Discher, D. ; Cheng, J.

MRS Bulletin 2009, 34, 422-431. DOI : 10.1557/mrs2009.118.

Immune control of tuberculosis by IFN-gamma-inducible LRG-47Hydrothermal Growth of Large-scale Micropatterned Arrays of Ultralong ZnO Nanowires and Nanobelts on Zinc Substrate

Lu, C. ; Qi, L. ; Yang J. ; Tang, L. ; Zhang, D. ; Ma, J.

Chem. Commun. 2006, 3551-3553. DOI : 10.1039/B608151G.

Efficient and Stable Cell Surface Coupling of Nanoparticles

Irvine, D.J.; Zheng, Y.; Tang, L.

U.S. provisional patent application, 2015.

Carrier-Free Biologically-Active Protein Nanogels

Tang, L. ; Irvine, D.J.

US Patent 20150110740, 2015.

Silica Nanoparticle Agent Conjugates

Cheng, J. ; Tang, L.

US 61/418,230, 2010, WO PCT/US2011/062548, 2011 (TF09149).