Journal Articles

2020

Hydrogel-based milliwell arrays for standardized and scalable retinal organoid cultures

S. Decembrini, S. Hoehnel, N. Brandenberg, Y. Arsenijevic & M. P. Lutolf

Scientific Reports

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In vitro endoderm emergence andself-organisation in the absence of extraembryonic tissues and embryonic architecture

S. Vianello & M. P. Lutolf

bioRxiv 

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The Effect of Thiol Structure on Allyl Sulfide Photodegradable Hydrogels and their Application as a Degradable Scaffold for Organoid Passaging

F. M. Yavitt, T. E. Brown, E. A. Hushka, M. E. Brown, N. Gjorevski, P. J. Dempsey, M. P. Lutolf & K. S. Anseth

Advanced Materials

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High-throughput automated organoid culture via stem-cell aggregation in microcavity arrays

N. Brandenberg, S. Hoehnel, F. Kuttler, K. Homicsko, C. Ceroni, T. Ringel, N, Gjorevski, G. Schwank, G. Coukos, G. Turcatti & M. P. Lutolf.

Nature Biomedical Engineering

Low-Defect Thiol-Michael Addition Hydrogels as Matrigel
Substitutes for Epithelial Organoid Derivation

S. Rezakhani, N. Gjorevski & M. P. Lutolf

Advanced Functional Materials

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Morphogenesis Guided by 3D Patterning of Growth Factors in Biological Matrices

N. Broguiere, I. Lüchtefeld, L. Trachsel, D. Mazunin, R. Rizzo, J. W. Bode, M. P. Lutolf & M. Zenobi-Wong

Advanced Materials

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Smart Hydrogels for the Augmentation of Bone Regeneration by Endogenous Mesenchymal Progenitor Cell Recruitment.

P. S. Lienemann, Q. Vallmajo-Martin, P. Papageorgiou, U. Blache, S. Metzger, A. S. Kiveliö, V. Milleret, A. Sala, S. Hoehnel, A. Roch, R. Reuten, M. Koch, O. Naveiras, F. E. Weber, W. Weber, M. P. Lutolf & M. Ehrbar

Advanced Science

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Antiangiogenic immunotherapy suppresses desmoplastic and chemoresistant intestinal tumors in mice.

S. Ragusa, B. Prat-Luri, A. González-Loyola, S. Nassiri, M. L. Squadrito, A. Guichard, S. Cavin, N. Gjorevski, D. Barras, G. Marra, M. P. Lutolf, J. Perentes, E. Corse, R. Bianchi, L. Wetterwald, J. Kim, G. Oliver, M. Delorenzi, M. De Palma & T. V. Petrova

The Journal of Clinical Investigation

2019

Synthetic 3D PEG-Anisogel Tailored with Fibronectin Fragments Induce Aligned Nerve Extension.

C. Licht, J. C. Rose, A. O. Anarkoli, D. Blondel, M. Roccio, T. Haraszti, D. B. Gehlen, J. A. Hubbell, M. P. Lutolf & L. De Laporte

Biomacromolecules

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High-throughput stem cell-based phenotypic screening through microniches

L. Kolb, S. Allazetta, M. Karlsson, M. Girgin, W. Weber & M. P. Lutolf

Biomaterials Science

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Engineered signaling centers for the spatially controlled patterning of human pluripotent stem cells

A. Manfrin, Y. Tabata, E. R. Paquet, A. R. Vuaridel, F. R. Rivest, F. Naef & M. P. Lutolf

Nature Methods

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Engineering Stem Cell Self-organization to Build Better Organoids.

J. A. Brassard, M. P. Lutolf

Cell Stem Cell

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Bioinspired Hydrogels for 3D Organoid Culture

D. Blondel & M. P. Lutolf

CHIMIA International Journal for Chemistry, PDF

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The NAD-Booster Nicotinamide Riboside Potently Stimulates Hematopoiesis through Increased Mitochondrial Clearance

N. Vannini, V. Campos, M. Girotra, V. Trachsel, S. Rojas-Sutterlin, J. Tratwal, S. Ragusa, E. Stefanidis, D.Ryu, P. Y. Rainer, G. Nikitin, S. Giger, T. Y. Li, A. Semilietof, A. Oggier, Y. Yersin, L. Tauzin, E. Pirinen, W.-C. Cheng, J. Ratajczak, C. Canto, M. Ehrbar, F. Sizzano, T. V. Petrova, D. Vanhecke, L. Zhang, P. Romero, A. Nahimana, S. Cherix, M. A. Duchosal, P.-C. Ho, B. Deplancke, G. Coukos, J. Auwerx, M. P. Lutolf & O.Naveiras,

Cell stem cell

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A bioactive injectable bulking material; a potential therapeutic approach for stress urinary incontinence

E.Vardar, G. Vythilingam, K. Pinnagoda, E. M. Engelhardt, P. Y. Zambelli, J. A. Hubbell, M .P. Lutolf, P. Freya & H. M. Larsson

Biomaterials

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Understanding the Mechanobiology of Early Mammalian Development through Bioengineered Models

S.Vianello & M. P. Lutolf

Developmental cell

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The heparin binding domain of von Willebrand factor binds to growth factors and promotes angiogenesis in wound healing

J. Ishihara, A.Ishihara, R. D. Starke, C. R. Peghaire, K. E. Smith, T. A. J. McKinnon, Y. Tabata, K. Sasaki, M. J. V. White, K. Fukunaga, M. A. Laffan, M. P. Lutolf, A. M. Randi & J. A Hubbell

Blood

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Tissue-Engineering the Intestine: The Trials before the Trials

Clevers, R. K. Conder, V. S.W. Li, M. P. Lutolf, L. Vallier, S. Chan, T. C. Grikscheit, K. B. Jensen & P. De Coppi

Cell stem cell

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Pharmacological induction of a progenitor state for the efficient expansion of primary human hepatocytes

C. Unzu, E. Planet, N. Brandenberg, F. Fusil, M. Cassano, J. Perez‐Vargas, M. Friedli, F.‐L. Cosset, M. P. Lutolf, B. E. Wildhaber, D. Trono

Hepatology

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2018

3D Inkjet Printing of Complex, Cell-Laden Hydrogel Structures

A. Negro, T. Cherbuin & M. P. Lutolf

Scientific Reports, PDF

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Multi-axial self-organization properties of mouse embryonic stem cells into gastruloids

L. Beccari, N. Moris, M. Girgin, D. A. Turner, P. Baillie-Johnson, A.-C. Cossy, M. P. Lutolf, D. Duboule & A. Martinez Arias

Nature

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Label-Free Quantification Proteomics for the Identification of Mesenchymal Stromal Cell Matrisome Inside 3D Poly(Ethylene Glycol) Hydrogels

Y. R. Devaud, E. Avilla-Royo, Ch. Trachsel, J. Grossmann, I. Martin, M. P. Lutolf & M Ehrbar

Advanced Healthcare Materials

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Microfluidic production of bioactive fibrin micro-beads embedded in crosslinked collagen used as an injectable bulking agent for urinary incontinence treatment

E. Vardara, H. M. Larsson, S. Allazetta, E. M. Engelhardt, K. Pinnagoda, G. Vythilingam, J. A. Hubbell, M. P .Lutolf, P. Frey

Acta Biomaterialia

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2017

Microfluidic Programming of Compositional Hydrogel Landscapes

S. Allazetta, A. Negro & M. P. Lutolf

Macromolecular Rapid Communications

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Multiscale microenvironmental perturbation of pluripotent stem cell fate and self-organization

Yoji Tabata & M. P. Lutolf

Scientific Reports, PDF

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Decoding of position in the developing neural tube from antiparallel morphogen gradients

M. Zagorski,  Y. Tabata, N. Brandenberg, M. P. Lutolf, G. Tkačik, T. Bollenbach, J. Briscoe & A. Kicheva

Science

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Single-cell analyses identify bioengineered niches for enhanced maintenance of hematopoietic stem cells

A. Roch, S. Giger, M. Girotra, V. Campos, N. Vannini, O. Naveiras, S. Gobaa & M. P. Lutolf

Nature Communications, PDF

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Synthesis and characterization of well-defined hydrogel matrices and their application to intestinal stem cell and organoid culture

N. Gjorevski & M. P. Lutolf

Nature Protocols

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Anteroposterior polarity and elongation in the absence of extra-embryonic tissues and of spatially localised signalling in gastruloids: mammalian embryonic organoids

D. A. Turner, M. Girgin, L. Alonso-Crisostomo, V. Trivedi, P. Baillie-Johnson, C. R. Glodowski, P. C. Hayward, J. Collignon, C. Gustavsen, P. Serup, B. Steventon, M. P. Lutolf, A. Martinez Arias

Development, PDF

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2016

Specification of haematopoietic stem cell fate via modulation of mitochondrial activity

N. Vannini, M. Girotra, O. Naveiras, G. Nikitin, V. Campos, S. Giger, A. Roch, J. Auwerx & M. P. Lutolf

Nature Communications, PDF

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Designer matrices for intestinal stem cell and organoid culture

G. Nikolche, S. Norman, M. Andrea, S. Giger, M. E. Bragina, P. Ordóñez-Morán, H. Clevers & M. P. Lutolf

Nature

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3D chemical characterization of frozen hydrated hydrogels using ToF-SIMS with argon cluster sputter depth profiling

M. Taylor, D. Scurr, M. P. Lutolf, L. Buttery, M. Zelzer & M. Alexander

Biointerphases, PDF

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Defined three-dimensional microenvironments boost induction of pluripotency

M. Caiazzo, Y. Okawa, A. Ranga, A. Piersigilli, Y. Tabata & M. P. Lutolf

Nature Materials

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Hyaluronic Acid Hydrogels Formed in Situ by Transglutaminase-Catalyzed Reaction

A. Ranga, M. P. Lutolf, J. Hilborn & D. A. Ossipov

Biomacromolecules

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NAD+ repletion improves mitochondrial and stem cell function and enhances life span in mice

H. Zhang, D. Ryu, Y. Wu, K. Gariani, X. Wang, P. Luan, D. D’Amico, E. R. Ropelle, M. P. Lutolf, R. Aebersold, K. Schoonjans, K. J. Menzies, J. Auwerx

Science

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In Situ Patterning of Microfluidic Networks in 3D Cell-Laden Hydrogels

Brandenberg N & M. P. Lutolf

Advanced Materials

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Neural tube morphogenesis in synthetic 3D microenvironments

Adrian Ranga, Mehmet Girgin, Andrea Meinhardt, Dominic Eberle, Massimiliano Caiazzo, Elly M. Tanaka & M. P. Lutolf

Proceedings of the National Academy of Sciences, PDF

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2015

Substrate stiffness heterogeneities disrupt endothelial barrier integrity in a micropillar model of heterogeneous vascular stiffening

J. A. VanderBurgh, H. Hotchkiss, A. Potharazu, P. V. Taufalele & C. A. Reinhart-King

Integrative Biology

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Capturing Cell–Cell Interactions via SNAP-tag and CLIP-tag Technology

S. Hoehnel & M. P. Lutolf

Bioconjugate Chemistry

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Brief Report: Single-Cell Analysis Reveals Cell Division-Independent Emergence of Megakaryocytes From Phenotypic Hematopoietic Stem Cells

A. Roch, V. Trachsel & M. P. Lutolf

Stem Cells

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Chronic inflammation imposes aberrant cell fate regeneration epithelia through mechanotransduction

Craig S. Nowell, Pascal D. Odermatt, L. Azzolin, S. Hoehnel, Erwin F. Wagner, Georg E. Fantner, M. P. Lutolf, Y. Barrandon, S. Piccolo & F. Radtke

Nature Cell Biology

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Substract elasticity modulates the responsiveness of mesenchymal stem cells to commitment cues

S. Gooba, S. Hoehnel & M. P. Lutolf

Integrative Biology

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Cell-Instructive Microgels with Tailor-Made Physicochemical Properties

S. Allazetta, L. Kolb, S. Zerbib, J. Bardy & M. P. Lutolf

Small

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Capturing Cell-Cell Interactions via SNAP-tag and CLIP-tag Technology

S. Hoehnel & M. P. Lutolf

Journal of  the American Chemical Society

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2014

D Reconstitution of the Patterned Neural Tube from Embryonic Stem Cells

A. Meinhardt, D. Eberle, A. Tazaki, A. Ranga, M. Niesche, M. Wilsch-Bräuninger, A. Stec, G. Schackert, M. P. Lutolf & E. M. Tanaka

Stem Cell Reports, PDF

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Locally controlling mesenchymal stem cell morphogenesis by 3D PDGF-BB gradients towards the establishment of an in vitro perivascular niche

P. S. Lienemann, Y. R. Devaud, R. Reuten, B. R. Simona, M. Karlsson, W. Weber, M. Koch, M. P. Lutolf, V. Milleret & M. Ehrbar

Integrative Biology

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Ultra-rapid prototyping of flexible, multi-layered microfluidic devices via razor writing

S. Cosson, L. G. Aeberli, N. Brandenberg & M. P. Lutolf

Lab on a Chip

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Microscale patterning of hydrogel stiffness through light-triggered uncaging of thiols

K. A. Mosiewicz, L. Kolb, A.J. van der Vliesab & M. P. Lutolf

Biomaterials Science

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3D Niche Microarrays for Systems-Level Analyses of Cell Fate

A. Ranga, S. Gobaa, Y. Okawa, K. Mosiewicz, A. Negro & M. P. Lutolf

Nature Communications, PDF

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Hydrogel Microfluidics for the Patterning of Pluripotent Stem Cells

S. Cosson & M. P. Lutolf

Scientific Reports, PDF

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Microfluidic Patterning of Protein Gradients on Biomimetic Hydrogel Substrates

S. Cosson & M. P. Lutolf

Methods in Cell Biology

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Development of bioactive hydrogel capsules for the 3D expansion of pluripotent stem cells in bioreactors

Y. Tabata, I. Horiguchi, M. P. Lutolf & Y. Sakai

Biomaterials Science

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A high-capacity cell macroencapsulation system supporting the long-term survival of genetically engineered allogeneic cells

A. Lathuilière, S. Cosson, M. P. Lutolf, B. L. Schneider & P. Aebischer

Biomaterials

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2013

A versatile approach to engineering biomolecule-presenting cellular microenvironments

P. S. Lienemann, M. Karlsson, A. Sala, H. M. Wischhusen, F. E. Weber, R. Zimmermann, W. Weber. M. P. Lutolf &M. Ehrbar

Advanced Healthcare Materials

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Microfluidic Synthesis of Cell-Type-Specific Artificial Extracellular Matrix Hydrogels

S. Allazetta, T. C. Hausherr & M. P. Lutolf

Biomacromolecules

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Hydrogel Microwell Arrays Allow the Assessment of Protease-Associated Enhancement of Cancer Cell Aggregation and Survival

D. Loessner, S. Kobel , J. A. Clements, M. P. Lutolf & D. W. Hutmacher

Microarrays, PDF

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Artificial three-dimensional niches deconstruct pancreas development in vitro

C. Greggio, F. De Franceschi, M. Figueiredo-Larsen, S. Gobaa, A. Ranga, H. Semb, M. P. Lutolf & A. Grapin-Botton

Development, PDF

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In Situ Cell Manipulation Through Enzymatic Hydrogel Photopatterning

K. A. Mosiewicz, L. Kolb, A. J. Van der Vlies, M. M. Martino, P. S. Lienemann, J. A. Hubbell, M. Ehrbar & M. P. Lutolf

Nature Materials

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A high-capacity cell macroencapsulation system supporting the long-term survival of genetically engineered allogeneic cells

A. Lathuilière, S. Cosson, M. Lütolf, B. Schneider & P. Aebischer

Biomaterials

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Cell specific ingrowth hydrogels

M. Bracher, D. Bezuidenhout, M.P. Lutolf, T. Franz, M. Sun, P. Zilla & N.H. Davies

Biomaterials

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A generic strategy for pharmacological caging of growth factors for tissue engineering

M. Karlsson, P.S. Lienemann, N. Sprossmann, K. Heilmann, T. Brummer, M. P. Lutolf, M. Ehrbar & W. Weber

Chemical Communications

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Live mammalian cell arrays

K. P. Woodruff, L.M. Fidalgo, S. Gobaa, M. Lutolf & S.J. Maerkl

Nature Methods

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Patterning of cell-instructive hydrogels by hydrodynamic flow focusing

S. Cosson, S. Allazetta & M. Lutolf

Lab on a Chip

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Heparin-binding domain of fibrin(ogen) binds growth factors and promotes tissue repair when incorporated within a synthetic matrix

M. M. Martino, P. S. Briquez, A. Ranga, M. P. Lutolf & J. A. Hubbell

Proceedings of the National Academy of Sciences, PDF

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Microfluidic Synthesis of Cell-Type-Specific Artificial Extracellular Matrix Hydrogels

S. Allazetta, T. C. Hausherr & M. P. Lutolf

Biomacromolecules

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Metabolic control of adult neural stem cell activity by Fasn-dependent lipogenesis

M. Knobloch, S. M. G. Braun, L. Zurkirchen, C. von Schoultz, N. Zamboni, M.J. Araúzo-Bravo, W. J. Kovacs, O. Karalay, U. Suter, R. A. C. Machado, M. Roccio, M. P. Lutolf, C. F. Semenkovich & S. Jessberger

Nature

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2012

Sorting Live Stem Cells Based on Sox2 mRNA Expression

H. M. Larsson, S. T. Lee, M. Roccio, D. Velluto, M. P. Lutolf, P. Frey, & J. A. Hubbell

Plos One, PDF

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Predicting Stem Cell Fate Changes by Differential Cell Cycle Progression Patterns

M. Roccio, D. Schmitter, M. Knobloch, Y. Okawa, D. Sage & M. P. Lutolf

Development, PDF

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Controlled Breast Cancer Microarrays for the Deconvolution of Cellular Multilayering and Density Effects upon Drug Responses

M. Håkanson, S. Kobel, M. P. Lutolf, M. Textor, E. Cukierman & M. Charnley

Plos One, PDF

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Automated Analysis of Single Stem Cells in Microfluidic Traps

S. A. Kobel, O. Burri, A. Griffa, M. Girotra, A. Seitz & M. P. Lutolf

Lab On A Chip

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High-throughput Clonal Analysis of Neural Stem Cells in Microarrayed Artificial Niches

M. Roccio, S. Gobaa & M. P. Lutolf

Integrative Biology

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Diagnostic Microchip to Assay 3D Colony-Growth Potential of Captured Circulating Tumor Cells

C. A. Bichsel, S. Gobaa, S. Kobel, C. Secondini, G. N. Thalmann, M. G. Cecchini & M. P. Lutolf

Lab On A Chip

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High-throughput Approaches for the Analysis of Extrinsic Regulators of Stem Cell Fate

A. Ranga & M. P. Lutolf

Current Opinion In Cell Biology

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Biomimetic Hydrogels for Controlled Biomolecule Delivery to Augment Bone Regeneration

P. S. Lienemann, M. P. Lutolf & M. Ehrbar

Advanced drug delivery reviews

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Identification of in vitro HSC Fate Regulators by Differential Lipid Raft Clustering

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Materials Science: Cell Environments Programmed with Light

M. P. Lutolf

Nature

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Microdrop Printing of Hydrogel Bioinks into 3D Tissue-Like Geometries

K. Pataky, T. Braschler, A. Negro, P. Renaud, M. P. Lutolf & J. Brugger

Advanced Materials

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Fabrication of PEG Hydrogel Microwell Arrays for High-throughput Single Stem Cell Culture and Analysis

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2011

Engineering 3D cell instructive microenvironments by rational assembly of artificial extracellular matrices and cell patterning

A. Sala, P. Haenseler, A. Ranga, M. P. Lutolf, J. Voeroes, M. Ehrbar & F.E. Weber

Integrative Biology

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Artificial niche microarrays for probing single stem cell fate in high throughput

S. Gobaa, S. Hoehnel, M. Roccio, A. Negro, S. Kobel & M.P. Lutolf

Nature Methods

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Biomaterials meet microfluidics: building the next generation of artificial niches

S. Kobel & M.P. Lutolf

Current Opinion in Biotechnology

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Programmable microfluidic patterning of protein gradients on hydrogels

S. Allazetta, S. Cosson & M. Lütolf

Chemical Communications

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Elucidating the Role of Matrix Stiffness in 3D Cell Migration and Remodeling

M. Ehrbar, A. Sala, P. Lienemann, A. Ranga, K. Mosiewicz, A. Bittermann, S.C. Rizzi, F.E. Weber & M.P. Lutolf

Biophysical Journal

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2010

Phosphopantetheinyl Transferase-Catalyzed Formation of Bioactive Hydrogels for Tissue Engineering

K. A. Mosiewicz, K. Johnsson & M. P. Lutolf

Journal of the American Chemical Society

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Bioengineered 3D Platform to Explore Cell-ECM Interactions and Drug Resistance of Epithelial Ovarian Cancer Cells

D. Loessner, K. S. Stok, M. P. Lutolf, D. W. Hutmacher, J. A. Clements & S. C. Rizzi

Biomaterials

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Substrate Elasticity Regulates Skeletal Muscle Stem Cell Self-Renewal in Culture

P. M. Gilbert, K. L. Havenstrite, P. M. Magnusson, A. Sacco, N. A. Leonardi, P. Kraft, N. K. Nguyen, S. Thrun, M. P. Lutolf & H. M. Blau

Science

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Optimization of Microfluidic Single Cell Trapping for Long-Term On-Chip Culture

S. Kobel, A. Valero, J. Latt, P. Renaud & M. P. Lutolf

Lab on a Chip

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High-throughput methods to define complex stem cell niches

S. Kobel & M. P. Lutolf

Biotechniques, PDF

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2009

Artificial stem cell niches

M.P. Lutolf & H.M. Blau

Advances Materials

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Integration column: microwell arrays for mammalian cell culture

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Perturbation of single hematopoietic stem cell fates in artificial niches

M.P. Lutolf, R. Doyonnas, K. Havenstrite, K. Koleckar & H.M. Blau

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Integration column: artificial ECM: expanding the cell biology toolbox in 3D

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Designing materials to direct stem-cell fate

M.P. Lutolf, P.M. Gilbert & H.M. Blau

Nature

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Biomaterials: Spotlight on hydrogels

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Micropatterning of hydrogels by soft embossing

S. Kobel, M. Limacher, S. Gobaa, T. Laroche & M.P. Lutolf

Langmuir

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2008

Synthetic Fibrin-like Matrix for Bone Tissue Engineering

F. E. Weber, M. P. Lutolf, S. C. Rizzi, J. A. Hubbell & M. Ehrbar

Annual Tissue Engineering and Regenerative Medicine Meeting

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Control of Adult Stem Cell Function in Bioengineered in vitro Niches

H. M. Blau & M. P. Lutolf

MRS Bulletin, Materials Research Society Symposium Proceedings

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Enhancing the Reliability and Throughput of Neurosphere Culture on Hydrogel Microwell Arrays

M. Cordey, M. Limacher, S. Kobel, V. Taylor & M. P. Lutolf

Stem Cells

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Part II: Fibroblasts Preferentially Migrate in the Direction of Principal Strain

G. P. Raeber, M. P. Lutolf & J. A. Hubbell

Biomechanics and modeling in mechanobiology

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Three-dimensional Extracellular Matrix-Directed Cardioprogenitor Differentiation: Systematic Modulation of a Synthetic Cell-Responsive PEG-Hydrogel

T. P. Kraehenbuehl, P. Zammaretti, A. J. Van der Vlies, R. G. Schoenmakers , M. P. Lutolf, Marisa E. Jaconi & J. A. Hubbell

Biomaterials

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2007

Biomolecular hydrogels formed and degraded via site-specific enzymatic reactions

M. Ehrbar, S.C. Rizzi, R.G. Schoenmakers, B.S. Miguel, J.A. Hubbell, F.E. Weber & M.P. Lutolf

Biomacromolecules

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Mechanisms of 3-D migration and matrix remodeling of fibroblasts within artificial ECMs

G.P. Raeber, M.P. Lutolf & J.A. Hubbell

Acta Biomaterialia

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Enzymatic formation of modular cell-instructive fibrin analogs for tissue engineering

M. Ehrbar, S.C. Rizzi, R. Hlushchuk , V. Djonov, A.H. Zisch, J.A. Hubbell, F.E. Weber & M.P. Lutolf

Biomaterials

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2005

Molecularly engineered PEG hydrogels: a novel model system for proteolytically mediated cell migration

G.P. Raeber, M.P. Lutolf & J.A. Hubbell

Biophysical Journal

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Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering

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The selective modulation of endothelial cell mobility on RGD peptide containing surfaces by YIGSR peptides

M.H. Fittkau, P. Zilla, D. Bezuidenhout, M.P. Lutolf, P. Human, J.A. Hubbell & N. Davies

Biomaterials

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2003

Biopolymeric delivery matrices for angiogenic growth factors

A.H. Zisch, M.P. Lutolf & J.A. Hubbell

Cardiovascular Pathology

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Cell-demanded release of VEGF from synthetic, biointeractive cell ingrowth matrices for vascularized tissue growth

A.H. Zisch, M.P. Lutolf, M. Ehrbar, G.P. Raeber, S.C. Rizzi, N. Davies, H. Schmökel, D. Bezuidenhout, V. Djonov, P. Zilla & J.A. Hubbell

FASEB Journal

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Synthesis and physicochemical characterization of end-linked poly(ethylene glycol)-co-peptide hydrogels formed by Michael-type addition

M.P. Lutolf & J.A. Hubbell

Biomacromolecules

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Repair of bone defects using synthetic mimetics of collagenous extracellular matrices

M.P. Lutolf, F.E. Weber, H.G. Schmoekel, J.C. Schense, T. Kohler, R. Müller & J.A. Hubbell

Nature Biotechnology

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Synthetic matrix metalloproteinase-sensitive hydrogels for the conduction of tissue regeneration: engineering cell-invasion characteristics

M.P. Lutolf, J.L. Lauer-Fields, H.G. Schmoekel, A.T. Metters, F.E. Weber, G.B. Fields & J.A. Hubbell

Proceedings of the National Academy of Sciences, PDF

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2002

Poly(ethylene glycol) Block Copolymers

N. Tirelli, M. P. Lutolf, A. Napoli & J. A. Hubbell

Reviews in Molecular Biotechnology, PDF

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2001

Systematic modulation of Michael-type reactivity of thiols through the use of charged amino acids

M.P. Lutolf, N. Tirelli, S. Cerritelli, L. Cavalli & J.A. Hubbell

Bioconjugation Chemistry

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Protein delivery from materials formed by self-selective conjugate addition reactions

D.L. Elbert, A.B. Pratt, M.P. Lutolf, S. Halstenberg, & J.A. Hubbell

Journal of Controlled Release