Our latest publications

Advancements in Nanomechanical Characterization and Biomolecular Imaging with Atomic force Microscopy

V. Cencen / G. Fantner (Dir.)  

Lausanne, EPFL, 2024. 

Mutant aerolysin and uses thereof

C. Cao; M. Dal Peraro 



PeSTo-Carbs: Geometric Deep Learning for Prediction of Protein-Carbohydrate Binding Interfaces

P. Bibekar; L. F. Krapp; M. Dal Peraro 

Journal Of Chemical Theory And Computation. 2024-04-11. Vol. 20, num. 8, p. 2985-2991. DOI : 10.1021/acs.jctc.3c01145.

Development of cysteine cathepsin inhibitors combined with cell type-specific delivery for the treatment of B-cell lymphoma and solid tumors

A. S. Petruzzella / E. Oricchio (Dir.)  

Lausanne, EPFL, 2024. 

Engineering novel protein interactions with therapeutic potential using deep learning-guided surface design

A. Marchand / B. E. Ferreira De Sousa Correia (Dir.)  

Lausanne, EPFL, 2024. 

S-acylation and lipid exchange at the ER-Golgi membrane contact sites regulate pathogen entry in human cells

M. U. Anwar / F. G. van der Goot Grunberg; G. D’Angelo (Dir.)  

Lausanne, EPFL, 2024. 

Predicting protein interactions using geometric deep learning on protein surfaces

F. Sverrisson / B. E. Ferreira De Sousa Correia; M. Bronstein (Dir.)  

Lausanne, EPFL, 2024. 

Investigating the intra-molecular and inter-molecular effects of post-translational modifications on intrinsically disordered protein regions and structured protein regions

Z. Zhang / M. Dal Peraro; H. Lashuel (Dir.)  

Lausanne, EPFL, 2024. 

Deep Learning-Assisted Single-Molecule Detection of Protein Post-translational Modifications with a Biological Nanopore

C. Cao; P. Magalhaes; L. F. Krapp; J. F. B. Juarez; S. F. Mayer et al. 

Acs Nano. 2023-12-19. Vol. 18, num. 2, p. 1504-1515. DOI : 10.1021/acsnano.3c08623.

From Sequence to Dynamics to Function: Computational Design of Allostery and Ligand Selectivity in G-Protein Coupled Receptors

M. Hijazi / P. D. Barth (Dir.)  

Lausanne, EPFL, 2024. 

Structural mechanism of mitochondrial membrane remodelling by human OPA1

A. von der Malsburg; G. M. Sapp; K. E. Zuccaro; A. von Appen; F. R. Moss et al. 

Nature. 2023-08-23. Vol. 620, num. 7976. DOI : 10.1038/s41586-023-06441-6.

Targeting TDP-43 Proteinopathies in Neurodegeneration by its Native-State Stabilization

L. Yang / H. Lashuel (Dir.)  

Lausanne, EPFL, 2024. 

Deconvolution of ex-vivo drug screening data and bulk tissue expression predicts the abundance and viability of cancer cell subpopulations

A. Coudray / D. Trono; G. La Manno (Dir.)  

Lausanne, EPFL, 2024. 

Quantitative characterization of the inorganic phosphate gene regulatory networks in S. cerevisiae and bottom up engineering an orthogonal gene network

S. Cheng / S. Maerkl (Dir.)  

Lausanne, EPFL, 2024. 

A Geometric Transformer for Structural Biology: Development and Applications of the Protein Structure Transformer

L. F. Krapp / M. Dal Peraro (Dir.)  

Lausanne, EPFL, 2023.