Deplancke lab – Laboratory of Systems Biology and Genetics
©EPFL, Deplancke's lab
The central research focus of the Laboratory of Systems Biology and Genetics (LSBG) is to understand genome organization, regulation, and variation and is broadly partitioned according to three major research pillars:
Adipo
In the “Adipo” pillar, we are characterizing the regulatory mechanisms driving mesenchymal stromal cell heterogeneity and function in adipose biology and other metabolically relevant processes.
Geno
In the “Geno” pillar, we are examining how variation in the regulatory code affects molecular and organismal diversity.
Techno
In the “Techo” pillar, we are developing novel microfluidic, high-throughput sequencing, single cell omic, and computational approaches, which are used to address biological questions in the other two pillars.
Latest news
11.02.2021
A new lab publication in Science Advances: “Extensive tissue-specific expression variation and novel regulators underlying circadian behavior.”
Read EPFL’s press release related to these breakthrough discoveries: “Genes that dance to the circadian rhythm.”
Discover press article from The Academic Times: “Biological clock varies due to gene expression, fruit fly study reveals.”
Listen to a recent interview on the RTS (in French) about this study.
08.02.2021
Congratulations to Dr. Guido Van Mierlo and Dr. Wouter Saelens on being awarded with the prestigious Marie-Curie fellowships!
19.01.2021
Daniel Alpern, Bart Deplancke, and Riccardo Dainese have developed a new technology – MERCURIUS – which offers a quick and cost-efficient way to analyse multiple gene expressions.
Our creations / innovations / inventions
Catalyze4life
Catalyze4life’s mission is to support translational projects and to educate to innovate
Junior European Drosophilia Investigators (JEDI)
The JEDIs are early career scientists working on Drosophila melanogaster in Europe.
Contact
Office Number: SV 3823
Administration: Joanna Rusnok
Office Number: SV 3515