Vous trouverez ci-dessous la liste de toutes les publications liées à l’Institut d’Infectiologie de la Faculté des sciences de la vie.

Si vous souhaitez sélectionner des publications spécifiques par thèmes ou par auteurs, veuillez utiliser le moteur de recherche des publications scientifiques de l’EPFL.


N. Matthey; S. Stutzmann; C. Stoudmann; N. Guex; C. Iseli et al. : Neighbor predation linked to natural competence fosters the transfer of large genomic regions in Vibrio cholerae; bioRxiv. 2019-04-24. DOI : 10.1101/618009.
M. M. Mueller; M. Salathe : Crowdbreaks: Tracking Health Trends Using Public Social Media Data and Crowdsourcing; Frontiers In Public Health. 2019-04-12. DOI : 10.3389/fpubh.2019.00081.
A. De Iaco; A. Coudray; J. Duc; D. Trono : DPPA2 and DPPA4 are necessary to establish a 2C‐like state in mouse embryonic stem cells; EMBO reports. 2019-04-04. DOI : 10.15252/embr.201847382.
J. Pontis; E. Planet; S. Offner; P. Turelli; J. Duc et al. : Hominoid-Specific Transposable Elements and KZFPs Facilitate Human Embryonic Genome Activation and Control Transcription in Naive Human ESCs; Cell Stem Cell. 2019-03-27. DOI : 10.1016/j.stem.2019.03.012.
M. G. Garcia-Arraez; F. Masson; J. C. P. Escobar; B. Lemaitre : Functional analysis of RIP toxins from the Drosophila endosymbiont Spiroplasma poulsonii; BMC Microbiology. 2019-02-20. DOI : 10.1186/s12866-019-1410-1.
M. T. M. Hannebelle; J. X. Y. Ven; H. A. Eskandarian; C. Toniolo; A. P. D. Nievergelt et al. : Time-Lapse Atomic Force Microscopy Reveals New End Take Off (Neto) Dynamics in Mycobacteria. 2019-02-15. 63rd Annual Meeting of the Biophysical-Society, Baltimore, MD, Mar 02-06, 2019. p. 324A-324A.
L. C. Metzger; N. Matthey; C. Stoudmann; E. J. Collas; M. Blokesch : Ecological implications of gene regulation by TfoX and TfoY among diverse Vibrio species; Environmental Microbiology. 2019-02-14. DOI : 10.1111/1462-2920.14562.
O. A. Sergeeva; F. G. van der Goot : Anthrax toxin requires ZDHHC5-mediated palmitoylation of its surface-processing host enzymes; Proceedings Of The National Academy Of Sciences Of The United States Of America. 2019-01-22. DOI : 10.1073/pnas.1812588116.
P. Maffucci; B. Bigio; F. Rapaport; A. Cobat; A. Borghesi et al. : Blacklisting variants common in private cohorts but not in public databases optimizes human exome analysis; Proceedings Of The National Academy Of Sciences Of The United States Of America. 2019-01-15. DOI : 10.1073/pnas.1808403116.
J. Arora; P. J. McLare; N. Chaturvedi; M. Carrington; J. Fellay et al. : HIV peptidome-wide association study reveals patient-specific epitope repertoires associated with HIV control; Proceedings Of The National Academy Of Sciences Of The United States Of America. 2019-01-15. DOI : 10.1073/pnas.1812548116.
M. Blokesch : Cellular Microbiology Interview - Dr. Melanie Blokesch; Cellular Microbiology. 2019-01-04. DOI : 10.1111/cmi.13002.
P.-Y. J. L. Helleboid : Beyond silence : a functional and evolutionary study of KRAB zinc finger proteins. Lausanne, EPFL, 2019. DOI : 10.5075/epfl-thesis-9388.
R. C. Sommer : Innovative Tools and in vivo Methods for Tuberculosis Drug Discovery and Development. Lausanne, EPFL, 2019. DOI : 10.5075/epfl-thesis-9248.
S. Langer; C. Hammer; K. Hopfensperger; L. Klein; D. Hotter et al. : HIV-1 Vpu is a potent transcriptional suppressor of NF-κB-elicited antiviral immune responses; eLife. 2019. DOI : 10.7554/eLife.41930.
M. A. Hanson; A. Dostálová; C. Ceroni; M. Poidevin; B. Lemaitre : Synergy and remarkable specificity of antimicrobial peptides in vivo using a systematic knockout approach; eLife. 2019. DOI : 10.7554/eLife.44341.001.
T. Smieszek; G. Lazzari; M. Salathé : Assessing the Dynamics and Control of Droplet- and Aerosol-Transmitted Influenza Using an Indoor Positioning System; Scientific Reports. 2019. DOI : 10.1038/s41598-019-38825-y.
S. M. Haag : Identification and characterisation of small-molecule inhibitors targeting STING. Lausanne, EPFL, 2019. DOI : 10.5075/epfl-thesis-9257.
M. Cassano; J.-F. Dufour : Inflammation and Microbiota Fingerprint: Delphi's Oracle for Nonalcoholic Fatty Liver Disease-Related Hepatocellular Carcinoma?; Hepatology. 2019-01-01. DOI : 10.1002/hep.30267.
N. Takahashi; A. Coluccio; C. W. Thorball; E. Planet; H. Shi et al. : ZNF445 is a primary regulator of genomic imprinting; Genes & Development. 2019-01-01. DOI : 10.1101/gad.320069.118.


A. Forrester; C. De Leonibus; P. Grumati; E. Fasana; M. Piemontese et al. : A selective ER‐phagy exerts procollagen quality control via a Calnexin‐FAM134B complex; The EMBO Journal. 2018-12-17. DOI : 10.15252/embj.201899847.
G. C. Pereira; L. Sanchez; P. M. Schaughency; A. Rubio-Roldan; J. A. Choi et al. : Properties of LINE-1 proteins and repeat element expression in the context of amyotrophic lateral sclerosis; Mobile Dna. 2018-12-15. DOI : 10.1186/s13100-018-0138-z.
C. Unzu; E. Planet; N. Brandenberg; F. Fusil; M. Cassano et al. : Pharmacological induction of a progenitor state for the efficient expansion of primary human hepatocytes; Hepatology. 2018-12-14. DOI : 10.1002/hep.30425.
C. Sala; N. T. Odermatt; P. Soler-Arnedo; M. F. Guelen; S. von Schultz et al. : EspL is essential for virulence and stabilizes EspE, EspF and EspH levels in Mycobacterium tuberculosis; Plos Pathogens. 2018-12-01. DOI : 10.1371/journal.ppat.1007491.
J. Pontis; T. W. Theunissen; R. Jaenisch; D. Trono : Evolutionarily recent transposable elements and their controllers regulate human early embryonic transcriptional networks. 2018-12-01. Conference on Changing the Face of Modern Medicine - Stem Cell and Gene Therapy, Lausanne, SWITZERLAND, Oct 16-19, 2018. p. A25-A25.
D. Trono : Retroelements, their polydactyl controllers and the specificity of human biology. 2018-12-01. Conference on Changing the Face of Modern Medicine - Stem Cell and Gene Therapy, Lausanne, SWITZERLAND, Oct 16-19, 2018. p. A6-A7.
A. Iouranova; A. Coudray; J. Duc; M. Imbeault; P. Turelli et al. : KRAB-ZFPs and transposable elements rewire early human embryonic development transcriptional networks. 2018-12-01. Conference on Changing the Face of Modern Medicine - Stem Cell and Gene Therapy, Lausanne, SWITZERLAND, Oct 16-19, 2018. p. A150-A150.
L. Simo-Riudalbas; E. Planet; J. Duc; D. Trono : Transposable element-driven transcripts as new cancer biomarkers. 2018-12-01. Conference on Changing the Face of Modern Medicine - Stem Cell and Gene Therapy, Lausanne, SWITZERLAND, Oct 16-19, 2018. p. A52-A52.
A. De Iaco; A. Coudray; D. Trono : DPPA2 and DPPA4 regulate expression of Dux in mouse embryonic stem cells. 2018-12-01. Conference on Changing the Face of Modern Medicine - Stem Cell and Gene Therapy, Lausanne, SWITZERLAND, Oct 16-19, 2018. p. A29-A29.
D. K. Fabian; K. Garschall; P. Klepsatel; G. Santos-Matos; E. Sucena et al. : Evolution of longevity improves immunity in Drosophila; Evolution Letters. 2018-12-01. DOI : 10.1002/evl3.89.
E. Cambau; P. Saunderson; M. Matsuoka; S. T. Cole; M. Kai et al. : Antimicrobial resistance in leprosy: results of the first prospective open survey conducted by a WHO surveillance network for the period 2009-15; Clinical Microbiology And Infection. 2018-12-01. DOI : 10.1016/j.cmi.2018.02.022.
S. Bibert; A. Wojtowicz; P. Taffe; P. E. Tarr; E. Bernasconi et al. : Interferon lambda 3/4 polymorphisms are associated with AIDS-related Kaposi's sarcoma; Aids. 2018-11-28. DOI : 10.1097/QAD.0000000000002004.
I. Iatsenko; J.-P. Boquete; B. Lemaitre; I. Iatsenko; J.-P. Boquete et al. : Microbiota-Derived Lactate Activates Production of Reactive Oxygen Species by the Intestinal NADPH Oxidase Nox and Shortens Drosophila Lifespan; Immunity. 2018-11-20. DOI : 10.1016/j.immuni.2018.09.017.
A. Lupien; A. Vocat; C. S.-Y. Foo; E. Blattes; J.-Y. Gillon et al. : Optimized Background Regimen for Treatment of Active Tuberculosis with the Next-Generation Benzothiazinone Macozinone (PBTZ169); Antimicrobial Agents And Chemotherapy. 2018-11-01. DOI : 10.1128/AAC.00840-18.
C. Baranowski; M. A. Welsh; L.-T. Sham; H. A. Eskandarian; H. C. Lim et al. : Maturing Mycobacterium smegmatis peptidoglycan requires non-canonical crosslinks to maintain shape; Elife. 2018-10-16. DOI : 10.7554/eLife.37516.
S. Glück; A. Ablasser : Innate immunosensing of DNA in cellular senescence; Current Opinion in Immunology. 2018-10-05. DOI : 10.1016/j.coi.2018.09.013.
I. Miguel-Aliaga; H. Jasper; B. Lemaitre : Anatomy and Physiology of the Digestive Tract of Drosophila melanogaster; Genetics. 2018-10-01. DOI : 10.1534/genetics.118.300224.
J. Piton; A. Vocat; A. Lupien; C. S. Foo; O. Riabova et al. : Structure-Based Drug Design and Characterization of Sulfonyl-Piperazine Benzothiazinone Inhibitors of DprE1 from Mycobacterium tuberculosis; Antimicrobial Agents And Chemotherapy. 2018-10-01. DOI : 10.1128/AAC.00681-18.
N. T. Odermatt; C. Sala; A. Benjak; S. T. Cole : Essential Nucleoid Associated Protein mIHF (Rv1388) Controls Virulence and Housekeeping Genes in Mycobacterium tuberculosis; Scientific Reports. 2018-09-21. DOI : 10.1038/s41598-018-32340-2.
I. Fregno; E. Fasana; T. J. Bergmann; A. Raimondi; M. Loi et al. : ER-to-lysosome-associated degradation of proteasome-resistant ATZ polymers occurs via receptor-mediated vesicular transport; EMBO Journal. 2018-09-03. DOI : 10.15252/embj.201899259.
A. Benjak; C. Avanzi; Y. Benito; F. Breysse; C. Chartier et al. : Highly Reduced Genome of the New Species Mycobacterium uberis, the Causative Agent of Nodular Thelitis and Tuberculoid Scrotitis in Livestock and a Close Relative of the Leprosy Bacilli; Msphere. 2018-09-01. DOI : 10.1128/mSphere.00405-18.
S. Girma; C. Avanzi; K. Bobosha; K. Desta; M. H. Idriss et al. : Evaluation of Auramine O staining and conventional PCR for leprosy diagnosis: A comparative cross-sectional study from Ethiopia; Plos Neglected Tropical Diseases. 2018-09-01. DOI : 10.1371/journal.pntd.0006706.
C. S. Foo; A. Lupien; M. Kienle; A. Vocat; A. Benjak et al. : Arylvinylpiperazine Amides, a New Class of Potent Inhibitors Targeting QcrB of Mycobacterium tuberculosis; Mbio. 2018-09-01. DOI : 10.1128/mBio.01276-18.
T. J. Bergmann; M. Molinari : Three branches to rule them all? UPR signalling in response to chemically versus misfolded proteins-induced ER stress; Biology of the Cell. 2018-09-01. DOI : 10.1111/boc.201800029.
A. Ablasser : Phase separation focuses DNA sensing; Science. 2018-08-17. DOI : 10.1126/science.aau6019.
K. Kawano; A. J. Doucet; M. Ueno; R. Kariya; W. An et al. : HIV-1 Vpr and p21 restrict LINE-1 mobility; Nucleic Acids Research. 2018-07-31. DOI : 10.1093/nar/gky688.
P. Scepanovic; C. Alanio; C. Hammer; F. Hodel; J. Bergstedt et al. : Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines; Genome Medicine. 2018-07-27. DOI : 10.1186/s13073-018-0568-8.
S. M. Jang; A. Kauzlaric; J.-P. Quivy; J. Pontis; B. Rauwel et al. : KAP1 facilitates reinstatement of heterochromatin after DNA replication; Nucleic Acids Research. 2018-06-28. DOI : 10.1093/nar/gky580.
C. Wymant; F. Blanquart; T. Golubchik; A. Gall; M. Bakker et al. : Easy and accurate reconstruction of whole HIV genomes from short-read sequence data with shiver; Virus Evolution. 2018-05-18. DOI : 10.1093/ve/vey007.
M. P. Martin; V. Naranbhai; P. R. Shea; Y. Qi; V. Ramsuran et al. : Killer cell immunoglobulin–like receptor 3DL1 variation modifies HLA-B*57 protection against HIV-1; Journal of Clinical Investigation. 2018-05-01. DOI : 10.1172/JCI98463.
E. Patin; M. Hasan; J. Bergstedt; V. Rouilly; V. Libri et al. : Natural variation in the parameters of innate immune cells is preferentially driven by genetic factors; Nature Immunology. 2018-03-19. DOI : 10.1038/s41590-018-0049-7.
S. Cordey; M.-A. Hartley; K. Keitel; F. Laubscher; F. Brito et al. : Detection of novel astroviruses MLB1 and MLB2 in the sera of febrile Tanzanian children; Emerging Microbes & Infections. 2018-03-14. DOI : 10.1038/s41426-018-0025-1.
J.-L. Raisaro; P. J. McLaren; J. Fellay; M. Cavassini; C. Klersy et al. : Are privacy-enhancing technologies for genomic data ready for the clinic? A survey of medical experts of the Swiss HIV Cohort Study; Journal of Biomedical Informatics. 2018-03-01. DOI : 10.1016/j.jbi.2017.12.013.
A. Coluccio; G. Ecco; J. Duc; S. Offner; P. Turelli et al. : Individual retrotransposon integrants are differentially controlled by KZFP/KAP1-dependent histone methylation, DNA methylation and TET-mediated hydroxymethylation in naïve embryonic stem cells; Epigenetics & Chromatin. 2018-02-26. DOI : 10.1186/s13072-018-0177-1.
V. Ramsuran; V. Naranbhai; A. Horowitz; Y. Qi; M. P. Martin et al. : Elevated HLA-A expression impairs HIV control through inhibition of NKG2A-expressing cells; Science. 2018-01-05. DOI : 10.1126/science.aam8825.
C. Toniolo; M. Delince; J. D. McKinney : A microfluidic cell-trapping device to study dynamic host-microbe interactions at the single-cell level; Microfluidics In Cell Biology, Pt B: Microfluidics In Single Cells. 2018-01-01. DOI : 10.1016/bs.mcb.2018.06.008.
N. Matthey; N. C. Drebes Dörr; M. Blokesch : Long-Read-Based Genome Sequences of Pandemic and Environmental Vibrio cholerae Strains; Microbiology Resource Announcements. 2018. DOI : 10.1128/MRA.01574-18.
P. Scepanovic : Genetic determinants of healthy human immune variance: from humoral response to microbiome diversity. Lausanne, EPFL, 2018. DOI : 10.5075/epfl-thesis-8955.
K. Shah : An Exploratory Study On The Functional Significance Of Eosinophil Residency In The Small Intestine Under Homeostatic Conditions. Lausanne, EPFL, 2018. DOI : 10.5075/epfl-thesis-7333.
J. P. Dudzic : The melanization reaction in Drosophila: More than black or white. Lausanne, EPFL, 2018. DOI : 10.5075/epfl-thesis-8934.
P. J. Soler Arnedo : Functional characterization of the virulence determinant ESX-1 from Mycobacterium tuberculosis. Lausanne, EPFL, 2018. DOI : 10.5075/epfl-thesis-9011.
A. Benjak; C. Avanzi; P. Singh; C. Loiseau; S. Girma et al. : Phylogenomics and antimicrobial resistance of the leprosy bacillus Mycobacterium leprae; Nature Communications. 2018. DOI : 10.1038/s41467-017-02576-z.
F. Glaus; D. Dedic; P. Tare; V. Nagaraja; L. Rodrigues et al. : Total Synthesis of Ripostatin B and Structure-Activity Relationship Studies on Ripostatin Analogs; JOURNAL OF ORGANIC CHEMISTRY. 2018. DOI : 10.1021/acs.joc.8b00193.
K. Filbey; T. Bouchery; G. Le Gros : The role of ILC2 in hookworm infection; PARASITE IMMUNOLOGY. 2018. DOI : 10.1111/pim.12429.
C. Guerra; G. Pisoni; T. Solda; M. Molinari : The reductase TMX1 contributes to ERAD by preferentially acting on membrane-associated folding-defective polypeptides; BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2018. DOI : 10.1016/j.bbrc.2018.06.099.
M. Zaballa; F. van der Goot : The molecular era of protein S-acylation: spotlight on structure, mechanisms, and dynamics; CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY. 2018. DOI : 10.1080/10409238.2018.1488804.
J. di Iulio; I. Bartha; E. Wong; H. Yu; V. Lavrenko et al. : The human noncoding genome defined by genetic diversity; NATURE GENETICS. 2018. DOI : 10.1038/s41588-018-0062-7.
S. Haag; M. Gulen; L. Reymond; A. Gibelin; L. Abrami et al. : Targeting STING with covalent small-molecule inhibitors; NATURE. 2018. DOI : 10.1038/s41586-018-0287-8.
C. Studle; Q. Vallmajo-Martin; A. Haumer; J. Guerrero; M. Centola et al. : Spatially confined induction of endochondral ossification by functionalized hydrogels for ectopic engineering of osteochondral tissues; BIOMATERIALS. 2018. DOI : 10.1016/j.biomaterials.2018.04.025.
H. A. Eskandarian : Revealing Bacterial Surface Physiology using Dual Atomic Force and Optical Time-Lapse Microscopy; Biophysical Journal. 2018. DOI : 10.1016/j.bpj.2017.11.2055.
M. Massara; M. Menotti; N. Bergamasco; N. Harris; T. Baehr-Jones et al. : Nonlinear characterization of a silicon integrated Bragg waveguide filter; OPTICS LETTERS. 2018. DOI : 10.1364/OL.43.001171.
A. Decout; A. Ablasser : Human cGAS Has a Slightly Different Taste for dsDNA; IMMUNITY. 2018. DOI : 10.1016/j.immuni.2018.08.005.
A. Rapin; N. Harris : Helminth-Bacterial Interactions: Cause and Consequence; TRENDS IN IMMUNOLOGY. 2018. DOI : 10.1016/
M. Jimenez; F. Alessandrini; S. Schindela; Y. Schober; A. Nockher et al. : Helminth products limit type 2 inflammation by directly suppressing granulocyte activation. 2018.
G. Lazzari; Y. Jaquet; D. Kebaili; L. Symul; M. Salathe : FoodRepo: An Open Food Repository of Barcoded Food Products; FRONTIERS IN NUTRITION. 2018. DOI : 10.3389/fnut.2018.00057.
M. da Silva; J. Portela; W. Li; M. Jackson; M. Gonzalez-Juarrero et al. : Evidence of zoonotic leprosy in Para A, Brazilian Amazon, and risks associated with human contact or consumption of armadillos; PLOS NEGLECTED TROPICAL DISEASES. 2018. DOI : 10.1371/journal.pntd.0006532.
A. Bhaskar; C. De Piano; E. Gelman; J. McKinney; N. Dhar : Elucidating the role of (p)ppGpp in mycobacterial persistence against antibiotics; IUBMB LIFE. 2018. DOI : 10.1002/iub.1888.
M. Loi; I. Fregno; C. Guerra; M. Molinari : Eat it right: ER-phagy and recovER-phagy; BIOCHEMICAL SOCIETY TRANSACTIONS. 2018. DOI : 10.1042/BST20170354.
A. Trompette; E. Gollwitzer; C. Pattaroni; I. Lopez-Mejia; E. Riva et al. : Dietary Fiber Confers Protection against Flu by Shaping Ly6c(-) Patrolling Monocyte Hematopoiesis and CD8(+) T Cell Metabolism; IMMUNITY. 2018. DOI : 10.1016/j.immuni.2018.04.022.
O. Naret; N. Chaturvedi; I. Bartha; C. Hammer; J. Fellay : Correcting for Population Stratification Reduces False Positive and False Negative Results in Joint Analyses of Host and Pathogen Genomes; Frontiers in Genetics. 2018. DOI : 10.3389/fgene.2018.00266.
T. Bergmann; I. Fregno; F. Fumagalli; A. Rinaldi; F. Bertoni et al. : Chemical stresses fail to mimic the unfolded protein response resulting from luminal load with unfolded polypeptides; JOURNAL OF BIOLOGICAL CHEMISTRY. 2018. DOI : 10.1074/jbc.RA117.001484.
L. Abriata; J. Rodrigues; M. Salathe; L. Patiny : Augmenting Research, Education, and Outreach with Client-Side Web Programming; TRENDS IN BIOTECHNOLOGY. 2018. DOI : 10.1016/j.tibtech.2017.11.009.
V. Schuenemann; C. Avanzi; B. Krause-Kyora; A. Seitz; A. Herbig et al. : Ancient Mycobacterium leprae genomes reveal an unexpected diversity of leprosy in medieval Europe.
V. Schuenemann; C. Avanzi; B. Krause-Kyora; A. Seitz; A. Herbig et al. : Ancient genomes reveal a high diversity of Mycobacterium leprae in medieval Europe; PLOS PATHOGENS. 2018. DOI : 10.1371/journal.ppat.1006997.
J. Maire; C. Vincent-Monegat; F. Masson; A. Zaidman-Remy; A. Heddi : An IMD-like pathway mediates both endosymbiont control and host immunity in the cereal weevil Sitophilus spp.; MICROBIOME. 2018. DOI : 10.1186/s40168-017-0397-9.
R. Kathayat; Y. Cao; P. Elvira; P. Sandoz; M. Zaballa et al. : Active and dynamic mitochondrial S-depalmitoylation revealed by targeted fluorescent probes; NATURE COMMUNICATIONS. 2018. DOI : 10.1038/s41467-017-02655-1.
M. Jimenez; A. Friedl; S. Schindela; P. Haimerl; Y. Schober et al. : A parasitic immunomodulator reprograms the arachidonic acid metabolism of macrophages via a p38 map kinase-dependent pathway. 2018.
L. Chiarelli; G. Mori; B. Orena; M. Esposito; T. Lane et al. : A multitarget approach to drug discovery inhibiting Mycobacterium tuberculosis PyrG and PanK; SCIENTIFIC REPORTS. 2018. DOI : 10.1038/s41598-018-21614-4.
S.-Y. C. Foo : More Medicines for Tuberculosis: Fuelling Drug Discovery against Mycobacterium tuberculosis. Lausanne, EPFL, 2018. DOI : 10.5075/epfl-thesis-8906.
T. Harumoto; B. Lemaitre : Male-killing toxin in a bacterial symbiont of Drosophila; Nature. 2018. DOI : 10.1038/s41586-018-0086-2.
Z. Zhai; J.-P. Boquete; B. Lemaitre; Z. Zhai; J.-P. Boquete et al. : Cell-Specific Imd-NF-κB Responses Enable Simultaneous Antibacterial Immunity and Intestinal Epithelial Cell Shedding upon Bacterial Infection; Immunity. 2018. DOI : 10.1016/j.immuni.2018.04.010.
F. Masson; S. Calderon Copete; F. Schüpfer; G. Garcia-Arraez; B. Lemaitre et al. : In Vitro Culture of the Insect Endosymbiont Spiroplasma poulsonii Highlights Bacterial Genes Involved in Host-Symbiont Interaction; mBio. 2018. DOI : 10.1128/mBio.00024-18.
T. Harumoto; T. Fukatsu; B. Lemaitre : Common and unique strategies of male killing evolved in two distinct Drosophila symbionts; Proceedings of the Royal Society B: Biological Sciences. 2018. DOI : 10.1098/rspb.2017.2167.
C. Van der Henst; A. S. Vanhove; N. C. Drebes Dörr; S. Stutzmann; C. Stoudmann et al. : Molecular insights into Vibrio cholerae’s intra-amoebal host-pathogen interactions; Nature Communications. 2018. DOI : 10.1038/s41467-018-05976-x.
N. C. Drebes Dörr; M. Blokesch : Bacterial type VI secretion system facilitates niche domination; Proceedings of the National Academy of Sciences. 2018. DOI : 10.1073/pnas.1812776115.
F. Le Roux; M. Blokesch : Eco-Evolutionary Dynamics Linked to Horizontal Gene Transfer in Vibrios; Annual Review of Microbiology. 2018. DOI : 10.1146/annurev-micro-090817-062148.
M. G. Garcia Arraez : The double-edged toxins. Lausanne, EPFL, 2018. DOI : 10.5075/epfl-thesis-8782.
D. W. Adams; S. Stutzmann; C. Stoudmann; M. Blokesch : DNA-uptake pilus of Vibrio cholerae capable of kin-discriminated auto-aggregation; bioRxiv. 2018. DOI : 10.1101/354878.
M. Jaskolska; S. Stutzmann; C. Stoudmann; M. Blokesch : QstR-dependent regulation of natural competence and type VI secretion in Vibrio cholerae; Nucleic Acids Research. 2018. DOI : 10.1093/nar/gky717.
A. Rapin : Intestinal helminths modulate the gut microbiome. EPFL, 2018. DOI : 10.5075/epfl-thesis-8275.
K. E. Schneider : Single-cell division and killing dynamics of bacteria exposed to isocratic and time-dependent concentrations of antibiotic. Lausanne, EPFL, 2018. DOI : 10.5075/epfl-thesis-8585.
C. Avanzi : Genomics: a Swiss army knife to fight leprosy. Lausanne, EPFL, 2018. DOI : 10.5075/epfl-thesis-8482.
F. Boldrin; G. Degiacomi; A. Serafini; G. S. Kolly; M. Ventura et al. : Promoter mutagenesis for fine-tuning expression of essential genes in Mycobacterium tuberculosis; Microbial Biotechnology. 2018. DOI : 10.1111/1751-7915.12875.
F. Bertels; A. Marzel; G. Leventhal; V. Mitov; J. Fellay et al. : Dissecting HIV Virulence: Heritability of Setpoint Viral Load, CD4+ T Cell Decline and Per-Parasite Pathogenicity; Molecular biology and evolution. 2018. DOI : 10.1093/molbev/msx246.
E. Adland; M. Hill; N. Lavandier; A. Csala; A. Edwards et al. : Differential immunodominance hierarchy of CD8+ T cell responses in HLA-B*27:05 and B*27:02-mediated control of HIV-1 infection; Journal of virology. 2018. DOI : 10.1128/JVI.01685-17.
L. Abel; J. Fellay; D. W. Haas; E. Schurr; G. Srikrishna et al. : Genetics of human susceptibility to active and latent tuberculosis: present knowledge and future perspectives; The Lancet. Infectious Diseases. 2018. DOI : 10.1016/S1473-3099(17)30623-0.


S. Glück; B. Guey; M. F. Gulen; K. Wolter; T.-W. Kang et al. : Innate immune sensing of cytosolic chromatin fragments through cGAS promotes senescence; Nature Cell Biology. 2017-09-19. DOI : 10.1038/ncb3586.
N. L. Harris; P. Loke : Recent Advances in Type-2-Cell-Mediated Immunity: Insights from Helminth Infection; Immunity. 2017. DOI : 10.1016/j.immuni.2017.11.015.
A. D. Pananos; T. M. Bury; C. Wang; J. Schonfeld; S. P. Mohanty et al. : Critical dynamics in population vaccinating behavior; Proceedings Of The National Academy Of Sciences Of The United States Of America. 2017. DOI : 10.1073/pnas.1704093114.
A. Benjak; T. P. Honap; C. Avanzi; E. Becerril-Villanueva; I. Estrada-Garcia et al. : Insights from the Genome Sequence of Mycobacterium lepraemurium: Massive Gene Decay and Reductive Evolution; Mbio. 2017. DOI : 10.1128/mBio.01283-17.
N. Altemose; N. Noor; E. Bitoun; A. Tumian; M. Imbeault et al. : A map of human PRDM9 binding provides evidence for novel behaviors of PRDM9 and other zinc-finger proteins in meiosis; Elife. 2017. DOI : 10.7554/e.Life.28383.
K. Jensen; K. P. Lund; K. B. Christensen; A. T. Holm; L. K. Dubey et al. : M-ficolin is present in Aspergillus fumigatus infected lung and modulates epithelial cell immune responses elicited by fungal cell wall polysaccharides; Virulence. 2017. DOI : 10.1080/21505594.2016.1278337.
E. M. Leitman; C. B. Willberg; M.-H. Tsai; H. Chen; S. Buus et al. : HLA-B*14:02-Restricted Env-Specific CD8+ T-Cell Activity Has Highly Potent Antiviral Efficacy Associated with Immune Control of HIV Infection; Journal of virology. 2017. DOI : 10.1128/JVI.00544-17.
P. J. McLaren; S. L. Pulit; D. Gurdasani; I. Bartha; P. R. Shea et al. : Evaluating the Impact of Functional Genetic Variation on HIV-1 Control; The Journal of infectious diseases. 2017. DOI : 10.1093/infdis/jix470.
B. Piasecka; D. Duffy; A. Urrutia; H. Quach; E. Patin et al. : Distinctive roles of age, sex, and genetics in shaping transcriptional variation of human immune responses to microbial challenges; Proceedings of the National Academy of Sciences of the United States of America. 2017. DOI : 10.1073/pnas.1714765115.
W.-B. A. Chng; R. Koch; X. Li; S. Kondo; E. Nagoshi et al. : Transforming Growth Factor beta/Activin signaling in neurons increases susceptibility to starvation; Plos One. 2017. DOI : 10.1371/journal.pone.0187054.
A. Yanagawa; C. Neyen; B. Lemaitre; F. Marion-Poll : The gram-negative sensing receptor PGRP-LC contributes to grooming induction in Drosophila; Plos One. 2017. DOI : 10.1371/journal.pone.0185370.
A.-S. Foscolos; I. Papanastasiou; A. Tsotinis; N. Kolocouris; G. B. Foscolos et al. : Synthesis of Adamantane Aminoethers with Antitubercular Potential; Medicinal Chemistry. 2017. DOI : 10.2174/1573406413666170125112709.
B. Volpe : Role of myeloid cells in mediating protection against parasitic helminth larvae. Lausanne, EPFL, 2017. DOI : 10.5075/epfl-thesis-8219.
N. T. Odermatt : Functional Characterization of Nucleoid Associated Proteins Acting as Global Transcription Factors in Mycobacterium tuberculosis. Lausanne, EPFL, 2017. DOI : 10.5075/epfl-thesis-8176.
A. Coluccio : KRAB'n'KAP, DNA methylation and epigenetic memory. Lausanne, EPFL, 2017. DOI : 10.5075/epfl-thesis-8070.
T. Bouchery; B. Volpe; G. L. Legros; N. Harris : Dialogue Between Neutrophils And Hookworms Determines Parasite Development. 2017. 65th Annual Meeting of the American-Society-of-Tropical-Medicine-and-Hygiene (ASTMH), Atlanta, GA, NOV 13-16, 2016. p. 606-606.
E. G. Salina; O. Ryabova; A. Vocat; B. Nikonenko; S. T. Cole et al. : New 1-hydroxy-2-thiopyridine derivatives active against both replicating and dormant Mycobacterium tuberculosis; Journal Of Infection And Chemotherapy. 2017. DOI : 10.1016/j.jiac.2017.04.012.
L. K. Dubey; P. Karempudi; S. A. Luther; B. Ludewig; N. L. Harris : Interactions between fibroblastic reticular cells and B cells promote mesenteric lymph node lymphangiogenesis; Nature Communications. 2017. DOI : 10.1038/s41467-017-00504-9.
V. Cardoso; J. Chesné; H. Ribeiro; B. García-Cassani; T. Carvalho et al. : Neuronal regulation of type 2 innate lymphoid cells via neuromedin U; Nature. 2017. DOI : 10.1038/nature23469.
N. T. Odermatt; C. Sala; A. Benjak; G. S. Kolly; A. Vocat et al. : Rv3852 (H-NS) of Mycobacterium tuberculosis Is Not Involved in Nucleoid Compaction and Virulence Regulation; Journal Of Bacteriology. 2017. DOI : 10.1128/Jb.00129-17.
M. Gengenbacher; M. A. Duque-Correa; P. Kaiser; S. Schuerer; D. Lazar et al. : NOS2-deficient mice with hypoxic necrotizing lung lesions predict outcomes of tuberculosis chemotherapy in humans; Scientific Reports. 2017. DOI : 10.1038/s41598-017-09177-2.
A. Dostalova; S. Rommelaere; M. Poidevin; B. Lemaitre : Thioester-containing proteins regulate the Toll pathway and play a role in Drosophila defence against microbial pathogens and parasitoid wasps; Bmc Biology. 2017. DOI : 10.1186/s12915-017-0408-0.
T. J. Bergmann; F. Fumagalli; M. Loi; M. Molinari : Role of SEC62 in ER maintenance: A link with ER stress tolerance in SEC62-overexpressing tumors?; Molecular & Cellular Oncology. 2017. DOI : 10.1080/23723556.2016.1264351.
F. Blanquart; C. Wymant; M. Cornelissen; A. Gall; M. Bakker et al. : Viral genetic variation accounts for a third of variability in HIV-1 set-point viral load in Europe; Plos Biology. 2017. DOI : 10.1371/journal.pbio.2001855.
Z. Zhai; J.-P. Boquete; B. Lemaitre : A genetic framework controlling the differentiation of intestinal stem cells during regeneration in Drosophila; Plos Genetics. 2017. DOI : 10.1371/journal.pgen.1006854.
M. M. A. Stefani; C. Avanzi; S. Buhrer-Sekula; A. Benjak; C. Loiseau et al. : Whole genome sequencing distinguishes between relapse and reinfection in recurrent leprosy cases; Plos Neglected Tropical Diseases. 2017. DOI : 10.1371/journal.pntd.0005598.
B. Roche; B. Gaillard; L. Leger; R. Pelagie-Moutenda; T. Sochacki et al. : An ecological and digital epidemiology analysis on the role of human behavior on the 2014 Chikungunya outbreak in Martinique; Scientific Reports. 2017. DOI : 10.1038/s41598-017-05957-y.
K. Ginda; I. Santi; D. Bousbaine; J. Zakrzewska-Czerwinska; D. Jakimowicz et al. : The studies of ParA and ParB dynamics reveal asymmetry of chromosome segregation in mycobacteria; Molecular Microbiology. 2017. DOI : 10.1111/mmi.13712.
G. Ecco; M. Imbeault; D. Trono : KRAB zinc finger proteins; Development. 2017. DOI : 10.1242/dev.132605.
M. Vlachou; A. Siamidi; E. Diamantidi; A. Iliopoulou; I. Papanastasiou et al. : In vitro Controlled Release from Solid Pharmaceutical Formulations of two new Adamantane Aminoethers with Antitubercular Activity (I).; Drug Research. 2017. DOI : 10.1055/s-0042-121491.
B. Niesler; S. Mohr; N. Hattensperger; C. Martinez; L. Houghton et al. : A functional SNP of the serotonin transporter gene promoter is associated with IBS. 2017. p. 50-50.
S. Asgari; L. J. Schlapbach; S. Anchisi; C. Hammer; I. Bartha et al. : Severe viral respiratory infections in children with IFIH1 loss-of-function mutations; Proceedings of the National Academy of Sciences of the United States of America. 2017. DOI : 10.1073/pnas.1704259114.
A. Rinaldo; E. Bertuzzo; M. Blokesch; L. Mari; M. Gatto : Modeling Key Drivers of Cholera Transmission Dynamics Provides New Perspectives for Parasitology; Trends in Parasitology. 2017. DOI : 10.1016/
A. Rapin; C. Pattaroni; B. J. Marsland; N. Harris : Microbiota Analysis Using an Illumina MiSeq Platform to Sequence 16S rRNA Genes; Current protocols in mouse biology. 2017. DOI : 10.1002/cpmo.29.
W. Ahmed; C. Sala; S. R. Hegde; R. K. Jha; S. T. Cole et al. : Transcription facilitated genome-wide recruitment of topoisomerase I and DNA gyrase; Plos Genetics. 2017. DOI : 10.1371/journal.pgen.1006754.
B. M. Meijer; S. M. Jang; I. C. Guerrera; C. Chhuon; J. Lipecka et al. : Threonine eliminylation by bacterial phosphothreonine lyases rapidly causes cross-linking of mitogen-activated protein kinase (MAPK) in live cells; Journal Of Biological Chemistry. 2017. DOI : 10.1074/jbc.M117.775940.
T. Bouchery; N. L. Harris : Only Two Can Tango: Mast Cells Displace Epithelial Cells to Dance with ILC2s; Immunity. 2017. DOI : 10.1016/j.immuni.2017.04.020.
T. Bouchery; N. L. V. Harris : Specific repair by discerning macrophages; Science. 2017. DOI : 10.1126/science.aan6782.
J. Burgi; B. Kunz; L. Abrami; J. Deuquet; A. Piersigilli et al. : CMG2/ANTXR2 regulates extracellular collagen VI which accumulates in hyaline fibromatosis syndrome; Nature Communications. 2017. DOI : 10.1038/ncomms15861.
L. Song; M. Jenner; J. Masschelein; C. Jones; M. J. Bull et al. : Discovery and Biosynthesis of Gladiolin: A Burkholderia gladioli Antibiotic with Promising Activity against Mycobacterium tuberculosis; Journal Of The American Chemical Society. 2017. DOI : 10.1021/jacs.7b03382.
D. Trono : A KRABsody for Embryo-Placental Development; Developmental Cell. 2017. DOI : 10.1016/j.devcel.2017.06.005.
J.-W. Veening; M. Blokesch : Interbacterial predation as a strategy for DNA acquisition in naturally competent bacteria; Nature Reviews Microbiology. 2017. DOI : 10.1038/nrmicro.2017.66.
Z. Huang; H. Lin; J. Fellay; Z. Kutalik; J.-P. Hubaux : SQC: Secure Quality Control for Meta-Analysis of Genome-Wide Association Studies; Bioinformatics. 2017. DOI : 10.1093/bioinformatics/btx193.
L. X. M. Lebon : The microbiota provides colonisation resistance against intestinal helminths by regulating intestinal physiology. Lausanne, EPFL, 2017. DOI : 10.5075/epfl-thesis-7670.
S. Senzani; D. Li; A. Bhaskar; C. Ealand; J. Chang et al. : An Amidase_3 domain-containing N-acetylmuramyl-L-alanine amidase is required for mycobacterial cell division; Scientific Reports. 2017. DOI : 10.1038/s41598-017-01184-7.
S. Cabezas; S. Ho; U. Ros; M. E. Lanio; C. Alvarez et al. : Damage of eukaryotic cells by the pore-forming toxin sticholysin II: Consequences of the potassium efflux; Biochimica Et Biophysica Acta-Biomembranes. 2017. DOI : 10.1016/j.bbamem.2017.02.001.
M. A. Ansari; V. Pedergnana; C. L. C. Ip; A. Magri; A. Von Delft et al. : Genome-to-genome analysis highlights the effect of the human innate and adaptive immune systems on the hepatitis C virus; Nature Genetics. 2017. DOI : 10.1038/ng.3835.
M. Leroy; J. Piton; L. Gilet; O. Pellegrini; C. Proux et al. : Rae1/YacP, a new endoribonuclease involved in ribosome-dependent mRNA decay in Bacillus subtilis; Embo Journal. 2017. DOI : 10.15252/embj.201796540.
A. De Iaco; E. Planet; A. Coluccio; S. Verp; J. Duc et al. : DUX-family transcription factors regulate zygotic genome activation in placental mammals; Nature Genetics. 2017. DOI : 10.1038/ng.3858.
B. Lemaitre : Science, narcissism and the quest for visibility; Febs Journal. 2017. DOI : 10.1111/febs.14032.
J. Piton; C. S. -Y. Foo; S. T. Cole : Structural studies of Mycobacterium tuberculosis DprE1 interacting with its inhabitors; Drug Discovery Today. 2017. DOI : 10.1016/j.drudis.2016.09.014.
S. T. Cole : Tuberculosis drug discovery needs public-private consortia; Drug Discovery Today. 2017. DOI : 10.1016/j.drudis.2016.09.026.
A. Flahault; A. Geissbuhler; I. Guessous; P. J. Guerin; I. Bolon et al. : Precision global health in the digital age; Swiss Medical Weekly. 2017. DOI : 10.4414/smw.2017.14423.
Y. Lou; J. Rybniker; C. Sala; S. T. Cole : EspC forms a filamentous structure in the cell envelope of Mycobacterium tuberculosis and impacts ESX-1 secretion; Molecular Microbiology. 2017. DOI : 10.1111/mmi.13575.
V. Singh; N. Dhar; J. Pato; G. S. Kolly; J. Kordulakova et al. : Identification of aminopyrimidine-sulfonamides as potent modulators of Wag31-mediated cell elongation in mycobacteria; Molecular Microbiology. 2017. DOI : 10.1111/mmi.13535.
M. Blokesch : In and out—contribution of natural transformation to the shuffling of large genomic regions; Current Opinion in Microbiology. 2017. DOI : 10.1016/j.mib.2017.04.001.
K. Sarter; M. Kulagin; G. Schett; N. L. Harris; M. M. Zaiss : Inflammatory arthritis and systemic bone loss are attenuated by gastrointestinal helminth parasites; Autoimmunity. 2017. DOI : 10.1080/08916934.2016.1261837.
A. J. Mcfarlane; H. J. Mcsorley; D. J. Davidson; P. M. Fitch; C. Errington et al. : Enteric helminth-induced type I interferon signaling protects against pulmonary virus infection through interaction with the microbiota; Journal of Allergy and Clinical Immunology. 2017. DOI : 10.1016/j.jaci.2017.01.016.
M. Cassano; S. Offner; E. Planet; A. Piersigilli; S. M. Jang et al. : Polyphenic trait promotes liver cancer in a model of epigenetic instability; Hepatology. 2017. DOI : 10.1002/hep.29182.
M. Grisi; F. Vincent; B. Volpe; R. Guidetti; N. Harris et al. : NMR spectroscopy of single sub-nL ova with inductive ultra-compact single-chip probes; Scientific reports. 2017. DOI : 10.1038/srep44670.
A. Verpoorte : A Microfluidic Platform Enables Large-Scale Single-Cell Screening to Identify Genes Involved in Bacterial Persistence. Lausanne, EPFL, 2017. DOI : 10.5075/epfl-thesis-7641.
F. Masson; B. Lemaitre : Protection from within; Elife. 2017. DOI : 10.7554/eLife.24111.
W.-B. A. Chng; V. Hietakangas; B. Lemaitre : Physiological Adaptations to Sugar Intake: New Paradigms from Drosophila melanogaster; Trends In Endocrinology And Metabolism. 2017. DOI : 10.1016/j.tem.2016.11.003.
I. Bartha; P. J. Mclaren; C. Brumme; R. Harrigan; A. Telenti et al. : Estimating the Respective Contributions of Human and Viral Genetic Variation to HIV Control; PLoS Computational Biology. 2017. DOI : 10.1371/journal.pcbi.1005339.
G. Degiacomi; A. Benjak; J. Madacki; F. Boldrin; R. Provvedi et al. : Essentiality of mmpL3 and impact of its silencing on Mycobacterium tuberculosis gene expression; Scientific Reports. 2017. DOI : 10.1038/srep43495.
A. Borghesi; M. Stronati; J. Fellay : Neonatal Group B Streptococcal Disease in Otherwise Healthy Infants: Failure of Specific Neonatal Immune Responses; Frontiers In Immunology. 2017. DOI : 10.3389/fimmu.2017.00215.
A. Kauzlaric; G. Ecco; M. Cassano; J. Duc; M. Imbeault et al. : The mouse genome displays highly dynamic populations of KRAB-zinc finger protein genes and related genetic units; PLoS One. 2017. DOI : 10.1371/journal.pone.0173746.
M. Imbeault; P.-Y. Helleboid; D. Trono : KRAB zinc-finger proteins contribute to the evolution of gene regulatory networks; Nature. 2017. DOI : 10.1038/nature21683.
A. Isakova; R. Groux; M. Imbeault; P. Rainer; D. Alpern et al. : SMiLE-seq identifies binding motifs of single and dimeric transcription factors; Nature methods. 2017. DOI : 10.1038/nmeth.4143.
R. Abujaber; P. R. Shea; P. J. Mclaren; S. Lakhi; J. Gilmour et al. : No Evidence for Association of beta-Defensin Genomic Copy Number with HIV Susceptibility, HIV Load during Clinical Latency, or Progression to AIDS; Annals Of Human Genetics. 2017. DOI : 10.1111/ahg.12182.
V. Singh; S. Donini; A. Pacitto; C. Sala; R. C. Hartkoorn et al. : The Inosine Monophosphate Dehydrogenase, GuaB2, Is a Vulnerable New Bactericidal Drug Target for Tuberculosis; Acs Infectious Diseases. 2017. DOI : 10.1021/acsinfecdis.6b00102.
M. Elitas; N. Dhar; K. Schneider; A. Valero; T. Braschler et al. : Dielectrophoresis as a single cell characterization method for bacteria; Biomedical Physics & Engineering Express. 2017. DOI : 10.1088/2057-1976/3/1/015005.
A. Kauzlaric : Genomic targets and molecular partners of the chromatin regulator KAP1. Lausanne, EPFL, 2017. DOI : 10.5075/epfl-thesis-7373.
P. A. Sandoz : Regulation of Endoplasmic Reticulum Architecture by Protein S-Palmitoylation. Lausanne, EPFL, 2017. DOI : 10.5075/epfl-thesis-7429.


S. Cole; J. L. Rybniker ; Benzimidazole sulfide derivatives for the treatment or prevention of tuberculosis. EP3250205 ; WO2016120259 ; EP3050565 . 2016.
J. L. Raisaro; E. Ayday; P. Mclaren; J.-p. Hubaux; A. Telenti et al. ; Method for privacy-preserving medical risk test. US9524370 ; US2016125141 ; EP3016011 . 2016.
J. Rybniker; S. Cole; G. Keri; L. Orfi; J. Pato et al. ; Benzothiophene, benzyloxybenzylidene and indoline derivatives useful for the treatment of tuberculosis. US2017240522 ; EP3194366 ; WO2016041972 . 2016.
D. V. Bonzon; G. H. Muller; P. Renaud; Y. Barrandon; J.-b. Bureau et al. ; Devices, systems and methods for dispensing and analysing particles. AU2016248031 ; WO2016166729 . 2016.
C. Stewart; M. V. Albertovich ; 2-homopiperazine-1-yl-4h-1,3-benzothiazine-4-one derivatives and process for the preparation of 2- (homo)piperazine 1,3-benzothiazine-4-one hydrochlorides. WO2016151011 ; CA2980653 ; EP3072889 . 2016.
D.-b. Sutherland; M. M. Zaiss ; Archaebacteria in bioactive animal feed, method of making the composition and methods employing the composition. AU2016231809 ; SG11201706961R ; CA2979781 ; WO2016147121 . 2016.
D. Trono; M. Friedli; C. Unzu Ezquerro ; Method for assessing the quality of various cells including induced pluripotent stem cells. WO2016193141 . 2016.
M. Salathe : Digital Pharmacovigilance and Disease Surveillance: Combining Traditional and Big-Data Systems for Better Public Health; Journal Of Infectious Diseases. 2016. DOI : 10.1093/infdis/jiw281.
T. Bouchery; N. L. Harris : Exploiting Old Pathogens to Create New Therapeutics; Cell Host & Microbe. 2016. DOI : 10.1016/j.chom.2016.11.007.
N. Dhar; J. Mckinney; G. Manina : Phenotypic Heterogeneity in Mycobacterium tuberculosis; Microbiology Spectrum. 2016. DOI : 10.1128/microbiolspec.TBTB2-0021-2016.
D. Trono : Switzerland and the Digital Health Revolution; Chimia. 2016. DOI : 10.2533/chimia.2016.851.
T. Junier; M. Rotger; E. Biver; B. Ledergerber; C. Barcelo et al. : Contribution of Genetic Background and Clinical Risk Factors to Low-Trauma Fractures in Human Immunodeficiency Virus (HIV)-Positive Persons: The Swiss HIV Cohort Study; Open Forum Infectious Diseases. 2016. DOI : 10.1093/ofid/ofw101.
K. Dietz; M. De Los Reyes Jimenez; E. Gollwitzer; A. Chaker; U. Zissler et al. : Age-dependent regulation of remodeling factors during allergic airway inflammation. 2016. Meeting of the European-Academy-of-Allergy-and-Clinical-Immunology, Vienna, AUSTRIA, JUN 11-15, 2016. p. 31-32.
S. Asgari; P. J. Mclaren; J. Peake; M. Wong; R. Wong et al. : Exome Sequencing Reveals Primary Immunodeficiencies in Children with Community-Acquired Pseudomonas aeruginosa Sepsis; Frontiers In Immunology. 2016. DOI : 10.3389/fimmu.2016.00357.
N. Chaturvedi; R. K. Chodavarapu; E. S. Svarovskaia; H. Mo; A. O. Osinusi et al. : Multiple HCV Amino Acid Variants Associate with Interferon Lambda Polymorphism in Genotype 1a, 1b and 3a Infections. 2016. 67th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD), Boston, MA, NOV 11-15, 2016. p. 33A-33A.
F. Licciardi; D. Montin; A. Versace; G. Migliore; C. Tzialla et al. : Familial segregation of group B streptococcal infection in a consanguineous kindred; International Journal Of Infectious Diseases. 2016. DOI : 10.1016/j.ijid.2016.08.010.
V. Ducret; M. R. Gonzalez; T. Scrignari; K. Perron : OprD Repression upon Metal Treatment Requires the RNA Chaperone Hfq in Pseudomonas aeruginosa; Genes. 2016. DOI : 10.3390/genes7100082.
E. Perrody; L. Abrami; M. Feldman; B. Kunz; S. Urbe et al. : Ubiquitin-dependent folding of the Wnt signaling coreceptor LRP6; Elife. 2016. DOI : 10.7554/eLife.19083.
F. Fumagalli; J. Noack; T. J. Bergmann; E. C. Presmanes; G. B. Pisoni et al. : Translocon component Sec62 acts in endoplasmic reticulum turnover during stress recovery; Nature Cell Biology. 2016. DOI : 10.1038/ncb3423.
P. Rusert; R. D. Kouyos; C. Kadelka; H. Ebner; M. Schanz et al. : Determinants of HIV-1 broadly neutralizing antibody induction; Nature Medicine. 2016. DOI : 10.1038/nm.4187.
C. S.-Y. Foo; B. Lechartier; G. S. Kolly; S. Boy-Rottger; J. Neres et al. : Characterization of DprE1-Mediated Benzothiazinone Resistance in Mycobacterium tuberculosis; Antimicrobial Agents And Chemotherapy. 2016. DOI : 10.1128/Aac.01523-16.
I. Iatsenko; S. Kondo; D. Mengin-Lecreulx; B. Lemaitre : PGRP-SD, an Extracellular Pattern-Recognition Receptor, Enhances Peptidoglycan-Mediated Activation of the Drosophila Imd Pathway; Immunity. 2016. DOI : 10.1016/j.immuni.2016.10.029.
A. Benard; C. Sala; G. Pluschke : Mycobacterium ulcerans Mouse Model Refinement for Pre-Clinical Profiling of Vaccine Candidates; Plos One. 2016. DOI : 10.1371/journal.pone.0167059.
Z. Huang; E. Ayday; H. Lin; R. S. Aiyar; A. Molyneaux et al. : A privacy-preserving solution for compressed storage and selective retrieval of genomic data; Genome Research. 2016. DOI : 10.1101/gr.206870.116.
Z. Wang; C. T. Bauch; S. Bhattacharyya; A. D'Onofrio; P. Manfredi et al. : Statistical physics of vaccination; Physics Reports-Review Section Of Physics Letters. 2016. DOI : 10.1016/j.physrep.2016.10.006.
T. J. Bergmann; G. B. Pisoni; M. Molinari : Quality control mechanisms of protein biogenesis: proteostasis dies hard; Aims Biophysics. 2016. DOI : 10.3934/biophy.2016.4.456.
Y. F. Inclan; A. Persat; A. Greninger; J. Von Dollen; J. Johnson et al. : A scaffold protein connects type IV pili with the Chp chemosensory system to mediate activation of virulence signaling in Pseudomonas aeruginosa; Molecular microbiology. 2016. DOI : 10.1111/mmi.13410.
A. D. Tischler; R. L. Leistikow; P. Ramakrishnan; M. I. Voskuil; J. D. Mckinney : Mycobacterium tuberculosis Phosphate Uptake System Component PstA2 Is Not Required for Gene Regulation or Virulence; Plos One. 2016. DOI : 10.1371/journal.pone.0161467.
T. Harumoto; H. Anbutsu; B. Lemaitre; T. Fukatsu : Male-killing symbiont damages host's dosage-compensated sex chromosome to induce embryonic apoptosis; Nature Communications. 2016. DOI : 10.1038/ncomms12781.
S. P. Mohanty; D. P. Hughes; M. Salathe : Using Deep Learning for Image-Based Plant Disease Detection; Frontiers In Plant Science. 2016. DOI : 10.3389/fpls.2016.01419.
A. Ablasser; M. F. Gulen : The role of cGAS in innate immunity and beyond; Journal Of Molecular Medicine-Jmm. 2016. DOI : 10.1007/s00109-016-1423-2.
S. Asgari; P. J. Mclaren; J. Peake; M. Wong; R. Wong et al. : Corrigendum: Exome Sequencing reveals Primary immunodeficiencies in Children with Community-Acquired Pseudomonas aeruginosa Sepsis (vol 7, 357, 2016); Frontiers In Immunology. 2016. DOI : 10.3389/fimmu.2016.00447.
S. T. Cole : Inhibiting Mycobacterium tuberculosis within and without; Philosophical Transactions Of The Royal Society B-Biological Sciences. 2016. DOI : 10.1098/rstb.2015.0506.
A. Ablasser; A. Dorhoi : Inflammasome Activation and Function During Infection with Mycobacterium tuberculosis; Inflammasome Signaling And Bacterial Infections; Cham: Springer Int Publishing Ag, 2016. p. 183-197.
A. Persat; J. G. Santiago : An Ohmic model for electrokinetic flows of binary asymmetric electrolytes; Current Opinion In Colloid & Interface Science. 2016. DOI : 10.1016/j.cocis.2016.06.001.
C. Avanzi; J. Del-Pozo; A. Benjak; K. Stevenson; V. R. Simpson et al. : Red squirrels in the British Isles are infected with leprosy bacilli; Science. 2016. DOI : 10.1126/science.aah3783.
M. Blokesch : Natural competence for transformation; Current Biology. 2016. DOI : 10.1016/j.cub.2016.08.058.
C. Avanzi; P. Busso; A. Benjak; C. Loiseau; A. Fomba et al. : Transmission of drug-resistant leprosy in Guinea-Conakry detected by molecular epidemiological approaches; Clinical Infectious Disease. 2016. DOI : 10.1093/cid/ciw572.
J. Martinez-Picado; P. J. Mclaren; I. Erkizia; M. P. Martin; S. Benet et al. : Identification of Siglec-1 null individuals infected with HIV-1; Nature Communications. 2016. DOI : 10.1038/ncomms12412.
N. Martin-Martin; M. Piva; J. Urosevic; P. Aldaz; J. D. Sutherland et al. : Stratification and therapeutic potential of PML in metastatic breast cancer; Nature Communications. 2016. DOI : 10.1038/ncomms12595.
P. Murima; M. Zimmermann; T. Chopra; F. Pojer; G. Fonti et al. : A rheostat mechanism governs the bifurcation of carbon flux in mycobacteria; Nature Communications. 2016. DOI : 10.1038/ncomms12527.
S. Mohr; N. Hattensperger; C. Martinez; S. Schmitteckert; L. A. Houghton et al. : A functional variant in the alternative serotonin transporter gene SLC6A4 promoter P2 has a potential impact on irritable bowel syndrome. 2016. p. 14-14.
G. Degiacomi; Y. Personne; G. Mondesert; X. Ge; C. S. Mandava et al. : Micrococcin P1-A bactericidal thiopeptide active against Mycobacterium tuberculosis; Tuberculosis. 2016. DOI : 10.1016/
L. Naldini; D. Trono; I. M. Verma : Lentiviral vectors, two decades later; Science. 2016. DOI : 10.1126/science.aah6192.
M. J. Delince; J.-B. Bureau; A. T. Lopez-Jimenez; P. Cosson; T. Soldati et al. : A microfluidic cell-trapping device for single-cell tracking of host-microbe interactions; Lab On A Chip. 2016. DOI : 10.1039/c6lc00649c.
M. Moyat; D. Velin : Use of VacA as a Vaccine Antigen; Toxins. 2016. DOI : 10.3390/toxins8060181.
M. Martinez-Hoyos; E. Perez-Herran; G. Gulten; L. Encinas; D. Alvarez-Gomez et al. : Antitubercular drugs for an old target: GSK693 as a promising InhA direct inhibitor; Ebiomedicine. 2016. DOI : 10.1016/j.ebiom.2016.05.006.
I. Iacovache; S. De Carlo; N. Cirauqui; M. Dal Peraro; F. G. van der Goot et al. : Cryo-EM structure of aerolysin variants reveals a novel protein fold and the pore-formation process; Nature Communications. 2016. DOI : 10.1038/ncomms12062.
J. Burgi; B. Xue; V. N. Uversky; F. G. van der Goot : Intrinsic Disorder in Transmembrane Proteins: Roles in Signaling and Topology Prediction; Plos One. 2016. DOI : 10.1371/journal.pone.0158594.
M. Bou Sleiman : The Drosophila gut response to infection. Lausanne, EPFL, 2016. DOI : 10.5075/epfl-thesis-7151.
B. Lemaitre : Connecting the obesity and the narcissism epidemics; Medical Hypotheses. 2016. DOI : 10.1016/j.mehy.2016.08.001.
C. Neyen; C. Runchel; F. Schüpfer; P. Meier; B. Lemaitre : The regulatory isoform rPGRP-LC induces immune resolution via endosomal degradation of receptors; Nature Immunology. 2016. DOI : 10.1038/ni.3536.
A. Espaillat; O. Forsmo; K. El Biari; R. Björk; B. Lemaitre et al. : Chemometric Analysis of Bacterial Peptidoglycan Reveals Atypical Modifications That Empower the Cell Wall against Predatory Enzymes and Fly Innate Immunity; Journal of the American Chemical Society. 2016. DOI : 10.1021/jacs.6b04430.
J. C. Paredes; J. K. Herren; F. Schüpfer; B. Lemaitre : The Role of Lipid Competition for Endosymbiont-Mediated Protection against Parasitoid Wasps in Drosophila; mBio. 2016. DOI : 10.1128/mBio.01006-16.
E. Ramond; C. Maclachlan; S. Clerc-Rosset; G. W. Knott; B. Lemaitre : Cell Division by Longitudinal Scission in the Insect Endosymbiont; mBio. 2016. DOI : 10.1128/mBio.00881-16.
Y. Lou : Structural and functional characterization of the mycobacterial ESX-1 secretion system. Lausanne, EPFL, 2016. DOI : 10.5075/epfl-thesis-7093.
D. Trono : Transposable Elements, Polydactyl Proteins, and the Genesis of Human-Specific Transcription Networks; Cold Spring Harbor symposia on quantitative biology. 2016. DOI : 10.1101/sqb.2015.80.027573.
G. Ecco; H. M. Rowe; D. Trono : A Large-Scale Functional Screen to Identify Epigenetic Repressors of Retrotransposon Expression; Methods in molecular biology (Clifton, N.J.). 2016. DOI : 10.1007/978-1-4939-3372-3_25.
T. W. Theunissen; M. Friedli; Y. He; E. Planet; R. C. O'Neil et al. : Molecular Criteria for Defining the Naive Human Pluripotent State; Cell stem cell. 2016. DOI : 10.1016/j.stem.2016.06.011.
M. J.-H. Delincé : Quantitative Single-Cell Analysis of Host-Pathogen Interactions. Lausanne, EPFL, 2016. DOI : 10.5075/epfl-thesis-7019.
C. Unzu; M. Friedli; A. Bosman; M. E. Jaconi; B. E. Wildhaber et al. : Human Hepatocyte-Derived Induced Pluripotent Stem Cells: MYC Expression, Similarities to Human Germ Cell Tumors, and Safety Issues; Stem Cells International. 2016. DOI : 10.1155/2016/4370142.
D. J. Klionsky; K. Abdelmohsen; A. Abe; M. J. Abedin; H. Abeliovich et al. : Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition); Autophagy. 2016. DOI : 10.1080/15548627.2015.1100356.
X. Sun; Z. Lu; X. Zhang; M. Salathe; G. Cao : Infectious Disease Containment Based on a Wireless Sensor System; Ieee Access. 2016. DOI : 10.1109/Access.2016.2551199.
Z. Yao; A. Wang; Y. Li; Z. Cai; B. Lemaitre et al. : The dual oxidase gene BdDuox regulates the intestinal bacterial community homeostasis of Bactrocera dorsalis; Isme Journal. 2016. DOI : 10.1038/ismej.2015.202.
L. Egana-Gorrono; A. C. Guardo; M. E. Bargallo; E. Planet; E. Vilaplana et al. : MicroRNA Profile in CD8+T-Lymphocytes from HIV-Infected Individuals: Relationship with Antiviral Immune Response and Disease Progression; Plos One. 2016. DOI : 10.1371/journal.pone.0155245.
D. W. Adams; L. J. Wu; J. Errington : A benzamide-dependent ftsZ mutant reveals residues crucial for Z-ring assembly; Molecular Microbiology. 2016. DOI : 10.1111/mmi.13286.
K. A. Robertson; W. Y. Hsieh; T. Forster; M. Blanc; H. Lu et al. : An Interferon Regulated MicroRNA Provides Broad Cell-Intrinsic Antiviral Immunity through Multihit Host-Directed Targeting of the Sterol Pathway; Plos Biology. 2016. DOI : 10.1371/journal.pbio.1002364.
S. Friebe; F. G. van der Goot; J. Buergi : The Ins and Outs of Anthrax Toxin; Toxins. 2016. DOI : 10.3390/toxins8030069.
P. An; S. Penugonda; C. W. Thorball; I. Bartha; J. J. Goedert et al. : Role of APOBEC3F Gene Variation in HIV-1 Disease Progression and Pneumocystis Pneumonia; Plos Genetics. 2016. DOI : 10.1371/journal.pgen.1005921.
P. Ramakrishnan; A. M. Aagesen; J. D. Mckinney; A. D. Tischler : Mycobacterium tuberculosis Resists Stress by Regulating PE19 Expression; Infection And Immunity. 2016. DOI : 10.1128/Iai.00942-15.
D. Morena; N. Maestro; F. Bersani; P. E. Forni; M. F. Lingua et al. : Hepatocyte Growth Factor-mediated satellite cells niche perturbation promotes development of distinct sarcoma subtypes; Elife. 2016. DOI : 10.7554/eLife.12116.
G. Ecco; M. Cassano; A. Kauzlaric; J. Duc; A. Coluccio et al. : Transposable Elements and Their KRAB-ZFP Controllers Regulate Gene Expression in Adult Tissues; Developmental Cell. 2016. DOI : 10.1016/j.devcel.2016.02.024.
G. Karabanovich; J. Zemanova; T. Smutny; R. Szekely; M. Sarkan et al. : Development of 3,5-Dinitrobenzylsulfanyl-1,3,4-oxadiazoles and Thiadiazoles as Selective Antitubercular Agents Active Against Replicating and Nonreplicating Mycobacterium tuberculosis; Journal Of Medicinal Chemistry. 2016. DOI : 10.1021/acs.jmedchem.5b00608.
A. Ablasser : ReGLUation of cGAS; Nature Immunology. 2016.
G. B. Pisoni; M. Molinari : Five Questions (with their Answers) on ER-Associated Degradation; Traffic. 2016. DOI : 10.1111/tra.12373.
N. Harris : IMMUNOLOGY. The enigmatic tuft cell in immunity; Science (New York, N.Y.). 2016. DOI : 10.1126/science.aaf5215.
N. L. Harris : Nicola L. Harris: Tracking Down That Gut Feeling; Trends in parasitology. 2016. DOI : 10.1016/
L. K. Dubey; L. Lebon; I. Mosconi; C.-Y. Yang; E. Scandella et al. : Lymphotoxin-Dependent B Cell-FRC Crosstalk Promotes De Novo Follicle Formation and Antibody Production following Intestinal Helminth Infection; Cell reports. 2016. DOI : 10.1016/j.celrep.2016.04.023.
J. Esser-von Bierren; N. Harris : Microbiome and Allergy; Encyclopedia of Immunobiology; Oxford: Academic Press, 2016. p. 336–345.
N. L. Harris : Intimate gut interactions: helminths and the microbiota; Cell research. 2016. DOI : 10.1038/cr.2016.72.
G. Ecco : Unraveling the KRAB/KAP1 control of transposable elements in pluripotent and somatic cells. Lausanne, EPFL, 2016. DOI : 10.5075/epfl-thesis-7020.
P. J. McLaren; J. L. Raisaro; M. Aouri; M. Rotger; E. Ayday et al. : Privacy-preserving genomic testing in the clinic: a model using HIV treatment; Genetics in medicine : official journal of the American College of Medical Genetics. 2016. DOI : 10.1038/gim.2015.167.
S. Chakrabarti; J. P. Dudzic; X. Li; E. J. Collas; J.-P. Boquete et al. : Remote Control of Intestinal Stem Cell Activity by Haemocytes in Drosophila; PLOS Genetics. 2016. DOI : 10.1371/journal.pgen.1006089.
S. Stutzmann; M. Blokesch : Circulation of a Quorum-Sensing-Impaired Variant of Vibrio cholerae Strain C6706 Masks Important Phenotypes; mSphere. 2016. DOI : 10.1128/mSphere.00098-16.
M. Bischofberger; I. Iacovache; D. Boss; F. Naef; F. G. van der Goot et al. : Revealing Assembly of a Pore-Forming Complex Using Single-Cell Kinetic Analysis and Modeling; Biophysical journal. 2016. DOI : 10.1016/j.bpj.2016.02.035.
L. C. Metzger; S. Stutzmann; T. Scrignari; C. Van der Henst; N. Matthey et al. : Independent Regulation of Type VI Secretion in Vibrio cholerae by TfoX and TfoY; Cell reports. 2016. DOI : 10.1016/j.celrep.2016.03.092.
S. Asgari : Host and pathogen genomics of severe pediatric infections. Lausanne, EPFL, 2016. DOI : 10.5075/epfl-thesis-6656.
G. Palazzolo; M. Quattrocelli; J. Toelen; R. Dominici; L. Anastasia et al. : Cardiac Niche Influences the Direct Reprogramming of Canine Fibroblasts into Cardiomyocyte-Like Cells; Stem Cells International. 2016. DOI : 10.1155/2016/4969430.
A. Maminska; A. Bartosik; M. Banach-Orlowska; I. Pilecka; K. Jastrzebski et al. : ESCRT proteins restrict constitutive NF-kappa B signaling by trafficking cytokine receptors; Science Signaling. 2016. DOI : 10.1126/scisignal.aad0848.
W.-T. He; X.-M. Zheng; Y.-H. Zhang; Y.-G. Gao; A.-X. Song et al. : Cytoplasmic Ubiquitin-Specific Protease 19 (USP19) Modulates Aggregation of Polyglutamine-Expanded Ataxin-3 and Huntingtin through the HSP90 Chaperone; Plos One. 2016. DOI : 10.1371/journal.pone.0147515.
C. Neyen; B. Lemaitre : Sensing Gram-negative bacteria: a phylogenetic perspective; Current Opinion In Immunology. 2016. DOI : 10.1016/j.coi.2015.10.007.
S. Landge; V. Ramachandran; A. Kumar; J. Neres; K. Murugan et al. : Nitroarenes as Antitubercular Agents: Stereoelectronic Modulation to Mitigate Mutagenicity; Chemmedchem. 2016. DOI : 10.1002/cmdc.201500462.
D. B. Sutherland; K. Suzuki; S. Fagarasan : Fostering of advanced mutualism with gut microbiota by Immunoglobulin A; Immunological Reviews. 2016. DOI : 10.1111/imr.12384.
R. Szekely; S. T. Cole : Mechanistic insight into mycobacterial MmpL protein function; Molecular Microbiology. 2016. DOI : 10.1111/mmi.13306.
A. Benjak; S. Uplekar; M. Zhang; J. Piton; S. T. Cole et al. : Genomic and transcriptomic analysis of the streptomycin-dependent Mycobacterium tuberculosis strain 18b; Bmc Genomics. 2016. DOI : 10.1186/s12864-016-2528-2.
G. Pavlovic; P. Mercier; V. Risson; P. Schmitt; M.-C. Birling et al. : The questions you should ask yourself for efficient CRISPR/Cas9 genome editing. 2016. p. 255-255.
T. Dallavilla; L. Abrami; P. A. Sandoz; G. Savoglidis; V. Hatzimanikatis et al. : Model-Driven Understanding of Palmitoylation Dynamics: Regulated Acylation of the Endoplasmic Reticulum Chaperone Calnexin; PLOS Computational Biology. 2016. DOI : 10.1371/journal.pcbi.1004774.
A. Kapopoulou; L. Mathew; A. Wong; D. Trono; J. D. Jensen : The evolution of gene expression and binding specificity of the largest transcription factor family in primates; Evolution. 2016. DOI : 10.1111/evo.12819.
M. Zaiss; N. Harris : The interaction of commensal intestinal bacteria with helminth parasites; Parasite Immunology. 2016. DOI : 10.1111/pim.12274.
S. E. Friebe : Folding and Endocytosis of Anthrax Toxin Receptors. Lausanne, EPFL, 2016. DOI : 10.5075/epfl-thesis-6923.
N. Matthey; M. Blokesch : The DNA-Uptake Process of Naturally Competent Vibrio cholerae; Trends in Microbiology. 2016. DOI : 10.1016/j.tim.2015.10.008.
L. C. Metzger; M. Blokesch : Regulation of competence-mediated horizontal gene transfer in the natural habitat of Vibrio cholerae; Current Opinion in Microbiology. 2016. DOI : 10.1016/j.mib.2015.10.007.
C. Van Der Henst; T. Scrignari; C. Maclachlan; M. Blokesch : An intracellular replication niche for Vibrio cholerae in the amoeba Acanthamoeba castellanii; The ISME Journal. 2016. DOI : 10.1038/ismej.2015.165.


D. Trono; B. Rauwel ; Methods for purging isolated organs and cells from latent human cytomegalovirus. WO2015091506 ; EP2886552 . 2015.
Z. Greff; Z. Varga; G. Kéri; L. Õrfi; J. Pató et al. ; 4-Pyrimidinylamino-benzenesulfonamide derivatives and their use for the inhibition of polo-like kinase 1 (PLK1) for the treatment of cancer and their use for the treatment of bacterial infections. US2015368209 ; EP2941428 ; WO2014106762 . 2015.
A. Persat; Y. F. Inclan; J. N. Engel; H. A. Stone; Z. Gitai : Type IV pili mechanochemically regulate virulence factors in Pseudomonas aeruginosa; Proceedings of the National Academy of Sciences of the United States of America. 2015. DOI : 10.1073/pnas.1502025112.
A. Persat; C. D. Nadell; M. K. Kim; F. Ingremeau; A. Siryaporn et al. : The mechanical world of bacteria; Cell. 2015. DOI : 10.1016/j.cell.2015.05.005.
N. Alejandra Gonzalez-Martinez; H. Gerardo Lozano-Garza; J. Castro-Garza; A. De Osio-Cortez; J. Vargas-Villarreal et al. : In Vivo Activity of the Benzothiazinones PBTZ169 and BTZ043 against Nocardia brasiliensis; PLoS Neglected Tropical Diseases. 2015. DOI : 10.1371/journal.pntd.0004022.
C. Hammer; M. Begemann; P. J. Mclaren; I. Bartha; A. Michel et al. : Amino Acid Variation in HLA Class II Proteins Is a Major Determinant of Humoral Response to Common Viruses; American Journal Of Human Genetics. 2015. DOI : 10.1016/j.ajhg.2015.09.008.
P. P. Becker; M. Rau; J. Schmitt; C. Malsch; C. Hammer et al. : Performance of Serum microRNAs-122,-192 and-21 as Biomarkers in Patients with Non-Alcoholic Steatohepatitis; Plos One. 2015. DOI : 10.1371/journal.pone.0142661.
M. M. Zaiss; A. Rapin; L. Lebon; L. K. Dubey; I. Mosconi et al. : The Intestinal Microbiota Contributes to the Ability of Helminths to Modulate Allergic Inflammation; Immunity. 2015. DOI : 10.1016/j.immuni.2015.09.012.
P. J. Mclaren; C. Coulonges; I. Bartha; T. L. Lenz; A. J. Deutsch et al. : Polymorphisms of large effect explain the majority of the host genetic contribution to variation of HIV-1 virus load; Proceedings Of The National Academy Of Sciences Of The United States Of America. 2015. DOI : 10.1073/pnas.1514867112.
R. Sharma; P. Singh; W. J. Loughry; J. M. Lockhart; W. B. Inman et al. : Zoonotic Leprosy in the Southeastern United States; Emerging Infectious Diseases. 2015. DOI : 10.3201/eid2112.150501.
Z. Zhai; S. Kondo; N. Ha; J.-P. Boquete; M. Brunner et al. : Accumulation of differentiating intestinal stem cell progenies drives tumorigenesis; Nature Communications. 2015. DOI : 10.1038/ncomms10219.
I. Bartha; A. Rausell; P. J. Mclaren; P. Mohammadi; M. Tardaguila et al. : The Characteristics of Heterozygous Protein Truncating Variants in the Human Genome; Plos Computational Biology. 2015. DOI : 10.1371/journal.pcbi.1004647.
S. M. Batt; M. Cacho Izquierdo; J. Castro Pichel; C. J. Stubbs; L. Vela-Glez Del Peral et al. : Whole Cell Target Engagement Identifies Novel Inhibitors of Mycobacterium tuberculosis Decaprenylphosphoryl-beta-D-ribose Oxidase; Acs Infectious Diseases. 2015. DOI : 10.1021/acsinfecdis.5b00065.
S. Landge; A. B. Mullick; K. Nagalapur; J. Neres; V. Subbulakshmi et al. : Discovery of benzothiazoles as antimycobacterial agents: Synthesis, structure-activity relationships and binding studies with Mycobacterium tuberculosis decaprenylphosphoryl-beta-D-ribose 2 '-oxidase; Bioorganic & Medicinal Chemistry. 2015. DOI : 10.1016/j.bmc.2015.11.017.
P. T. Hamilton; J. Votypka; A. Dostalova; V. Yurchenko; N. H. Bird et al. : Infection Dynamics and Immune Response in a Newly Described Drosophila-Trypanosomatid Association; Mbio. 2015. DOI : 10.1128/mBio.01356-15.
M. Demir : Monitoring the Cellular Cholesterol Distribution via nanoSIMS Imaging ; 2015 NCCR retreat, Eurotel Victoria, Villars-sur-Ollon, Vaud, Switzerland, June 3-5, 2015.
M. Demir : Monitoring the Cellular Cholesterol Distribution via NanoSIMS Imaging ; 6th International Singapore Lipid Symposium, National University of Singapore, Singapore, November 30, December 2, 2015.
F. Marzetta : Transposable elements and their KRAB/KAP1 controllers broadly regulate transcription in adult human cells. Lausanne, EPFL, 2015. DOI : 10.5075/epfl-thesis-6842.
E. Vayena; M. Salathé; L. C. Madoff; J. S. Brownstein : Ethical challenges of big data in public health; PLoS computational biology. 2015. DOI : 10.1371/journal.pcbi.1003904.
C. L. Althaus; M. Salathé : Measles Vaccination Coverage and Cases among Vaccinated Persons; Emerging infectious diseases. 2015. DOI : 10.3201/eid2108.150284.
S. Xiao; L. Zongqing; Z. Xiaomei; M. Salathé; C. Guohong : Targeted vaccination based on a wireless sensor system. 2015. Thirteenth IEEE International Conference on Pervasive Computing and Communications, St. Louis, Missouri, USA, March 23-27, 2015. p. 215-220. DOI : 10.1109/PERCOM.2015.7146531.
S. Tuarob; C. Tucker; M. Salathé; N. Ram : Modeling Individual-Level Infection Dynamics Using Social Network Information. 2015. The 24th ACM International Conference on Information and Knowledge Management, Melbourne, Australia, October 19-23, 2015. p. 1501-1510. DOI : 10.1145/2806416.2806575.
C. Adrover; T. Bodnar; Z. Huang; A. Telenti; M. Salathé : Identifying Adverse Effects of HIV Drug Treatment and Associated Sentiments Using Twitter; JMIR Public Health and Surveillance. 2015. DOI : 10.2196/publichealth.4488.
J. -Y. Gillon; B. Lechartier; V. A. Makarov; S. T. Cole : Towards first in human clinical trial with the novel drug candidate PBTZ169. 2015. p. 24-24.
M. L. T. Ang; P. Murima; K. Pethe : Next-generation antimicrobials: from chemical biology to first-in-class drugs; Archives Of Pharmacal Research. 2015. DOI : 10.1007/s12272-015-0645-0.
M. F. Gulen; A. Ablasser : Inside Job: Viruses Transfer cGAMP between Cells; Cell Host & Microbe. 2015. DOI : 10.1016/j.chom.2015.08.008.
M. Torres; D. B. Medinas; J. M. Matamala; U. Woehlbier; V. H. Cornejo et al. : The Protein-disulfide Isomerase ERp57 Regulates the Steady-state Levels of the Prion Protein; Journal Of Biological Chemistry. 2015. DOI : 10.1074/jbc.M114.635565.
R. K. Vijendravarma; S. Narasimha; S. Chakrabarti; A. Babin; S. Kolly et al. : Gut physiology mediates a trade-off between adaptation to malnutrition and susceptibility to food-borne pathogens; Ecology Letters. 2015. DOI : 10.1111/ele.12490.
G. B. Pisoni; L. W. Ruddock; N. Bulleid; M. Molinari : Division of labor among oxidoreductases: TMX1 preferentially acts on transmembrane polypeptides; Molecular Biology Of The Cell. 2015. DOI : 10.1091/mbc.E15-05-0321.
G. Farinelli; R. J. Hernandez; M. Migliavacca; E. Zonari; V. Capo et al. : Dual-regulated lentiviral vector for gene therapy of x-linked chronic granulomatous disease. 2015. Collaborative Congress of the European-Society-of-Gene-and-Cell-Therapy (ESGCT) and Finnish-Society-of-Gene-Therapy (FSGT), Helsinki, FINLAND, SEP 17-20, 2015. p. A51-A51.
M. Petridis; A. Benjak; G. M. Cook : Defining the nitrogen regulated transcriptome of Mycobacterium smegmatis using continuous culture; Bmc Genomics. 2015. DOI : 10.1186/s12864-015-2051-x.
N. Harris : IMMUNOLOGY Chronic effects of acute infections; Nature. 2015. DOI : 10.1038/526509a.
G. S. Kolly; R. Mukherjee; E. Kilacskova; L. A. Abriata; M. Raccaud et al. : GtrA Protein Rv3789 Is Required for Arabinosylation of Arabinogalactan in Mycobacterium tuberculosis; Journal Of Bacteriology. 2015. DOI : 10.1128/Jb.00628-15.
C. Unzu; M. Friedli; E. Planet; S. Offner; D. Trono et al. : Potential Of Induced Pluripotent Stem Cells For The Treatment Of Crigler-Najjar Liver Disease. 2015. 50th International Liver Congress of the European-Association-for-the-Study-of-the-Liver, Vienna, AUSTRIA, APR 22-26, 2015. p. S818-S818.
A. Vocat; R. C. Hartkoorn; B. Lechartier; M. Zhang; N. Dhar et al. : Bioluminescence for Assessing Drug Potency against Nonreplicating Mycobacterium tuberculosis; Antimicrobial Agents And Chemotherapy. 2015. DOI : 10.1128/Aac.00528-15.
J. Rullas; N. Dhar; J. D. Mckinney; A. Garcia-Perez; J. Lelievre et al. : Combinations of beta-Lactam Antibiotics Currently in Clinical Trials Are Efficacious in a DHP-I-Deficient Mouse Model of Tuberculosis Infection; Antimicrobial Agents And Chemotherapy. 2015. DOI : 10.1128/Aac.01063-15.
B. Lechartier; S. T. Cole : Mode of Action of Clofazimine and Combination Therapy with Benzothiazinones against Mycobacterium tuberculosis; Antimicrobial Agents And Chemotherapy. 2015. DOI : 10.1128/Aac.00395-15.
V. Makarov; J. Neres; R. C. Hartkoorn; O. B. Ryabova; E. Kazakova et al. : The 8-Pyrrole-Benzothiazinones Are Noncovalent Inhibitors of DprE1 from Mycobacterium tuberculosis; Antimicrobial Agents And Chemotherapy. 2015. DOI : 10.1128/Aac.00778-15.
J. P. Dudzic; S. Kondo; R. Ueda; C. M. Bergman; B. Lemaitre : Drosophila innate immunity: regional and functional specialization of prophenoloxidases; BMC biology. 2015. DOI : 10.1186/s12915-015-0193-6.
J. Bürgi : Unraveling the Physiological Role of Capillary Morphogenesis Gene 2 in Health and Disease. Lausanne, EPFL, 2015. DOI : 10.5075/epfl-thesis-6793.
N. Castro-Diaz; M. Friedli; D. Trono : Drawing a fine line on endogenous retroelement activity; Mobile genetic elements. 2015. DOI : 10.1080/2159256X.2015.1006109.
W. B. Chng : Redefining the metabolic landscape through TGF-beta/Activin signaling in Drosophila melanogaster. Lausanne, EPFL, 2015. DOI : 10.5075/epfl-thesis-6755.
M. Blanc; F. David; L. Abrami; D. Migliozzi; F. Armand et al. : SwissPalm: Protein Palmitoylation database; F1000Research. 2015. DOI : 10.12688/f1000research.6464.1.
M. Friedli; D. Trono : The Developmental Control of Transposable Elements and the Evolution of Higher Species; Annual review of cell and developmental biology. 2015. DOI : 10.1146/annurev-cellbio-100814-125514.
A. Tannous; G. B. Pisoni; D. N. Hebert; M. Molinari : N-linked sugar-regulated protein folding and quality control in the ER; Seminars In Cell & Developmental Biology. 2015. DOI : 10.1016/j.semcdb.2014.12.001.
G. Farinelli; M. Chiriaco; V. Capo; E. Zonari; M. Migliavacca et al. : Dual-Regulated Lentiviral Vector for Gene Therapy of X-Linked Chronic Granulomatous Disease. 2015. 18th Annual Meeting of the American-Society-of-Gene-and-Cell-Therapy (ASGCT), New Orleans, LA, MAY 13-16, 2015. p. S115-S116.
P. J. Mclaren; A. Gawanbacht; N. Pyndiah; C. Krapp; D. Hotter et al. : Identification of potential HIV restriction factors by combining evolutionary genomic signatures with functional analyses; Retrovirology. 2015. DOI : 10.1186/s12977-015-0165-5.
P. Leone; C. Bebeacua; O. Opota; C. Kellenberger; B. Klaholz et al. : X-ray and Cryo-electron Microscopy Structures of Monalysin Pore-forming Toxin Reveal Multimerization of the Pro-form; Journal Of Biological Chemistry. 2015. DOI : 10.1074/jbc.M115.646109.
E. Ramond; M. Meister; B. Lemaitre : From Embryo to Adult: Hematopoiesis along the Drosophila Life Cycle; Developmental Cell. 2015. DOI : 10.1016/j.devcel.2015.05.002.
P. J. Mclaren; M. Carrington : The impact of host genetic variation on infection with HIV-1; Nature Immunology. 2015. DOI : 10.1038/ni.3147.
A. Sipos; J. Pato; R. Szekely; R. C. Hartkoorn; L. Kekesi et al. : Lead selection and characterization of antitubercular compounds using the Nested Chemical Library; Tuberculosis. 2015. DOI : 10.1016/
L. Vera-Cabrera; W. Escalante-Fuentes; S. S. Ocampo-Garza; J. Ocampo-Candiani; C. A. Molina-Torres et al. : Mycobacterium lepromatosis Infections in Nuevo Leon, Mexico; Journal Of Clinical Microbiology. 2015. DOI : 10.1128/Jcm.03667-14.
R. Wassermann; M. F. Gulen; C. Sala; S. G. Perin; Y. Lou et al. : Mycobacterium tuberculosis Differentially Activates cGAS- and Inflammasome-Dependent Intracellular Immune Responses through ESX-1; Cell Host & Microbe. 2015. DOI : 10.1016/j.chom.2015.05.003.
J. C. Paredes; J. K. Herren; F. Schuepfer; R. Marin; S. Claverol et al. : Genome Sequence of the Drosophila melanogaster Male-Killing Spiroplasma Strain MSRO Endosymbiont; Mbio. 2015. DOI : 10.1128/mBio.02437-14.
E. Sollier; H. Amini; D. E. Go; P. A. Sandoz; K. Owsley et al. : Inertial microfluidic programming of microparticle-laden flows for solution transfer around cells and particles; Microfluidics And Nanofluidics. 2015. DOI : 10.1007/s10404-015-1547-7.
M. Brecik; I. Centarova; R. Mukherjee; G. S. Kolly; S. Huszar et al. : DprE1 Is a Vulnerable Tuberculosis Drug Target Due to Its Cell Wall Localization; Acs Chemical Biology. 2015. DOI : 10.1021/acschembio.5b00237.
M. S. B. Sleiman; D. Osman; A. Massouras; A. A. Hoffmann; B. Lemaitre et al. : Genetic, molecular and physiological basis of variation in Drosophila gut immunocompetence; Nature Communications. 2015. DOI : 10.1038/ncomms8829.
J. Rybniker; A. Vocat; C. Sala; P. Busso; F. Pojer et al. : Lansoprazole is an antituberculous prodrug targeting cytochrome bc1; Nature Communications. 2015. DOI : 10.1038/ncomms8659.
G. Mori; L. R. Chiarelli; M. Esposito; V. Makarov; M. Bellinzoni et al. : Thiophenecarboxamide Derivatives Activated by EthA Kill Mycobacterium tuberculosis by Inhibiting the CTP Synthetase PyrG; Chemistry & Biology. 2015. DOI : 10.1016/j.chembiol.2015.05.016.
N. Korotkova; J. Piton; J. M. Wagner; S. Boy-Roettger; A. Japaridze et al. : Structure of EspB, a secreted substrate of the ESX-1 secretion system of Mycobacterium tuberculosis; Journal Of Structural Biology. 2015. DOI : 10.1016/j.jsb.2015.06.003.
C. Neyen; B. Lemaitre : Different flavors of Toll guide olfaction; Trends In Immunology. 2015. DOI : 10.1016/
I. Speciale; I. Paciello; L. L. Fazio; L. Sturiale; A. Palmigiano et al. : Determination of the structure of the O-antigen and the lipid A from the entomopathogenic bacterium Pseudomonas entomophila lipopolysaccharide along with its immunological properties; Carbohydrate Research. 2015. DOI : 10.1016/j.carres.2015.04.017.
S. J. Tantry; G. Degiacomi; S. Sharma; L. K. Jena; A. Narayan et al. : Whole cell screen based identification of spiropiperidines with potent antitubercular properties; Bioorganic & Medicinal Chemistry Letters. 2015. DOI : 10.1016/j.bmcl.2015.05.087.
I. Mosconi; L. K. Dubey; B. Volpe; J. Esser-Von Bieren; M. M. Zaiss et al. : Parasite Proximity Drives the Expansion of Regulatory T Cells in Peyer's Patches following Intestinal Helminth Infection; Infection And Immunity. 2015. DOI : 10.1128/Iai.00266-15.
M. Blokesch : Competence-induced type VI secretion might foster intestinal colonization by Vibrio cholerae; BioEssays. 2015. DOI : 10.1002/bies.201500101.
M. R. Perkins; I. Bartha; J. K. Timmer; J. C. Liebner; D. Wollinsky et al. : The Interplay Between Host Genetic Variation, Viral Replication, and Microbial Translocation in Untreated HIV-Infected Individuals; The Journal of infectious diseases. 2015. DOI : 10.1093/infdis/jiv089.
M. Naveed; E. Ayday; E. Clayton; J. Fellay; C. Gunter et al. : Privacy in the Genomic Era; ACM Computing Surveys. 2015. DOI : 10.1145/2767007.
F. Le Roux; K. M. Wegner; C. Baker-Austin; L. Vezzulli; C. R. Osorio et al. : The emergence of Vibrio pathogens in Europe: ecology, evolution, and pathogenesis (Paris, 11–12th March 2015); Frontiers in Microbiology. 2015. DOI : 10.3389/fmicb.2015.00830.
J.-E. Dietrich; L. Panavaite; S. Gunther; S. Wennekamp; A. C. Groner et al. : Venus trap in the mouse embryo reveals distinct molecular dynamics underlying specification of first embryonic lineages; EMBO reports. 2015. DOI : 10.15252/embr.201540162.
L. Aimo; R. Liechti; N. Hyka-Nouspikel; A. Niknejad; A. Gleizes et al. : The SwissLipids knowledgebase for lipid biology; Bioinformatics (Oxford, England). 2015. DOI : 10.1093/bioinformatics/btv285.
S. Friebe; J. Deuquet; F. G. van der Goot : Differential dependence on N-glycosylation of anthrax toxin receptors CMG2 and TEM8; PloS one. 2015. DOI : 10.1371/journal.pone.0119864.
O. A. Sergeeva; F. G. van der Goot : Kicking Out Pathogens in Exosomes; Cell. 2015. DOI : 10.1016/j.cell.2015.05.040.
N. Dhar; V. Dubee; L. Ballell; G. Cuinet; J.-E. Hugonnet et al. : Rapid Cytolysis of Mycobacterium tuberculosis by Faropenem, an Orally Bioavailable beta-Lactam Antibiotic; Antimicrobial Agents And Chemotherapy. 2015. DOI : 10.1128/Aac.03461-14.
J. Neres; R. C. Hartkoorn; L. R. Chiarelli; R. Gadupudi; M. R. Pasca et al. : 2-Carboxyquinoxalines Kill Mycobacterium tuberculosis through Noncovalent Inhibition of DprE1; Acs Chemical Biology. 2015. DOI : 10.1021/cb5007163.
J. P. Hewitson; K. J. Filbey; J. E.-V. Bieren; M. Camberis; C. Schwartz et al. : Concerted Activity of IgG1 Antibodies and IL-4/IL-25-Dependent Effector Cells Trap Helminth Larvae in the Tissues following Vaccination with Defined Secreted Antigens, Providing Sterile Immunity to Challenge Infection; Plos Pathogens. 2015. DOI : 10.1371/journal.ppat.1004676.
I. Santi; J. D. Mckinney : Chromosome Organization and Replisome Dynamics in Mycobacterium smegmatis; Mbio. 2015. DOI : 10.1128/mBio.01999-14.
Z. Maglica; E. Oezdemir; J. D. Mckinney : Single-Cell Tracking Reveals Antibiotic-Induced Changes in Mycobacterial Energy Metabolism; Mbio. 2015. DOI : 10.1128/mBio.02236-14.
J. Noack; R. Bernasconi; M. Molinari : How Viruses Hijack the ERAD Tuning Machinery (vol 88, pg 10272, 2014); Journal Of Virology. 2015. DOI : 10.1128/Jvi.03670-14.
P. A. Sandoz; F. G. Van der Goot : How many lives does CLIMP-63 have?; Biochemical Society Transactions. 2015. DOI : 10.1042/Bst20140272.
P. Singh; A. Benjak; V. J. Schuenemann; A. Herbig; C. Avanzi et al. : Insight into the evolution and origin of leprosy bacilli from the genome sequence of Mycobacterium lepromatosis; Proceedings Of The National Academy Of Sciences Of The United States Of America. 2015. DOI : 10.1073/pnas.1421504112.
J. Merulla; T. Solda; M. Molinari : A novel UGGT1 and p97-dependent checkpoint for native ectodomains with ionizable intramembrane residue; Molecular Biology Of The Cell. 2015. DOI : 10.1091/mbc.E14-12-1615.
C. Neyen; O. Binggeli; P. Roversi; L. Bertin; M. B. Sleiman et al. : The Black cells phenotype is caused by a point mutation in the Drosophila pro-phenoloxidase 1 gene that triggers melanization and hematopoietic defects; Developmental And Comparative Immunology. 2015. DOI : 10.1016/j.dci.2014.12.011.
M. Blokesch : Leben und sterben lassen – horizontaler Gentransfer in Vibrio cholerae; BIOspektrum. 2015. DOI : 10.1007/s12268-015-0572-0.
A. J. Bretscher; V. Honti; O. Binggeli; O. Burri; M. Poidevin et al. : The Nimrod transmembrane receptor Eater is required for hemocyte attachment to the sessile compartment in Drosophila melanogaster; Biology Open. 2015. DOI : 10.1242/bio.201410595.
B. Rauwel; S. M. Jang; M. Cassano; A. Kapopoulou; I. Barde et al. : Release of human cytomegalovirus from latency by a KAP1/TRIM28 phosphorylation switch; eLife. 2015. DOI : 10.7554/eLife.06068.
J. Esser-von Bieren; B. Volpe; D. B. Sutherland; J. Bürgi; J. S. Verbeek et al. : Immune Antibodies and Helminth Products Drive CXCR2-Dependent Macrophage-Myofibroblast Crosstalk to Promote Intestinal Repair; PLoS pathogens. 2015. DOI : 10.1371/journal.ppat.1004778.
I. Bartha; J. Fellay : Adaptation on a genomic scale; eLife. 2015. DOI : 10.7554/eLife.06193.
P. J. McLaren; J. Fellay : Human genetic variation in HIV disease: beyond genome-wide association studies; Current opinion in HIV and AIDS. 2015. DOI : 10.1097/COH.0000000000000133.
S. Samani; Z. Huang; E. Ayday; M. Elliot; J. Fellay et al. : Quantifying Genomic Privacy via Inference Attack with High-Order SNV Correlations. 2015. 2nd International Workshop on Genome Privacy and Security (in conjunction with IEEE S&P 2015), San Jose, CA, USA, May 21, 2015.
Z. Huang; E. Ayday; J. Fellay; J.-P. Hubaux; A. Juels : GenoGuard: Protecting Genomic Data against Brute-Force Attacks. 2015. 36th IEEE Symposium on Security and Privacy (S&P 2015), San Jose, CA, USA, May 18-20, 2015.
K. Singh; M. Cassano; E. Planet; S. Sebastian; S. M. Jang et al. : A KAP1 phosphorylation switch controls MyoD function during skeletal muscle differentiation; Genes & development. 2015. DOI : 10.1101/gad.254532.114.
M. Blokesch : Protocols for Visualizing Horizontal Gene Transfer in Gram-Negative Bacteria Through Natural Competence; Hydrocarbon and Lipid Microbiology Protocols; Berlin: Humana Press, 2015. p. 1-16.
G. Manina; N. Dhar; J. D. Mckinney : Stress and Host Immunity Amplify Mycobacterium tuberculosis Phenotypic Heterogeneity and Induce Nongrowing Metabolically Active Forms; Cell Host & Microbe. 2015. DOI : 10.1016/j.chom.2014.11.016.
D. S. Lehmann; H. J. Ribaudo; E. S. Daar; R. M. Gulick; R. H. Haubrich et al. : Genome-wide association study of virologic response with efavirenz-containing or abacavir-containing regimens in AIDS clinical trials group protocols; Pharmacogenetics And Genomics. 2015. DOI : 10.1097/Fpc.0000000000000106.
J. E.-V. Bieren; B. Volpe; M. Kulagin; D. B. Sutherland; R. Guiet et al. : Antibody-Mediated Trapping of Helminth Larvae Requires CD11b and Fc gamma Receptor I; Journal Of Immunology. 2015. DOI : 10.4049/jimmunol.1401645.
N. Pennese : Evolutionally dynamic control of LINE-1 elements in embryonic stem cells. Lausanne, EPFL, 2015. DOI : 10.5075/epfl-thesis-6511.
Z. Huang; E. Ayday; J. Fellay; J.-P. Hubaux; A. Juels : GenoGuard: Protecting Genomic Data Against Brute-Force Attacks. 2015.
L. Fasching; A. Kapopoulou; R. Sachdeva; R. Petri; M. Jönsson et al. : TRIM28 Represses Transcription of Endogenous Retroviruses in Neural Progenitor Cells; Cell Reports. 2015. DOI : 10.1016/j.celrep.2014.12.004.
S. Borgeaud; L. C. Metzger; T. Scrignari; M. Blokesch : The type VI secretion system of Vibrio cholerae fosters horizontal gene transfer; Science. 2015. DOI : 10.1126/science.1260064.


D. Trono; I. Barde ; Modulation of mitophagy and use thereof. WO2014111876 ; WO2014111876 ; EP2757157 . 2014.
A. Persat; H. A. Stone; Z. Gitai : The curved shape of Caulobacter crescentus enhances surface colonization in flow; Nature communications. 2014. DOI : 10.1038/ncomms4824.
A. Persat; Z. Gitai : Bacterial evolution: rewiring modules to get in shape; Current biology : CB. 2014. DOI : 10.1016/j.cub.2014.04.022.
G. Dieppois; O. Opota; J. Lalucat; B. Lemaitre : Pseudomonas entomophila: A Versatile Bacterium with Entomopathogenic Properties; Pseudomonas; Dordrecht: Springer, 2014. p. 25-49.
S. Tuarob; C. S. Tucker; M. Salathe; N. Ram : An ensemble heterogeneous classification methodology for discovering health-related knowledge in social media messages; Journal of biomedical informatics. 2014. DOI : 10.1016/j.jbi.2014.03.005.
V. C. Barclay; T. Smieszek; J. He; G. Cao; J. J. Rainey et al. : Positive network assortativity of influenza vaccination at a high school: implications for outbreak risk and herd immunity; PloS one. 2014. DOI : 10.1371/journal.pone.0087042.
T. Smieszek; V. C. Barclay; I. Seeni; J. J. Rainey; H. Gao et al. : How should social mixing be measured: comparing web-based survey and sensor-based methods; BMC infectious diseases. 2014. DOI : 10.1186/1471-2334-14-136.
P. Yin; N. Ram; W.-C. Lee; C. Tucker; S. Khandelwal et al. : Two Sides of a Coin: Separating Personal Communication and Public Dissemination Accounts in Twitter. 2014. 18th Pacific-Asia Conference, PAKDD 2014, Tainan, Taiwan, May 13-16, 2014. p. 163-175. DOI : 10.1007/978-3-319-06608-0_14.
T. Bodnar; V. Barclay; N. Ram; C. Tucker; M. Salathé : On the ground validation of online diagnosis with Twitter and medical records. 2014. 23rd International World Wide Web Conference, Seoul, Korea, April 7-11, 2014. p. 651-656. DOI : 10.1145/2567948.2579272.
C. Adrover; T. Bodnar; M. Salathé : Targeting HIV-related Medication Side Effects and Sentiment Using Twitter Data; arXiv. 2014.
S. Friebe; L. Abrami; F. G. Van der Goot : Novel mechanistic insights into anthrax toxin endocytosis. 2014. ASCB/IFCB Meeting.
P. D. Townsend; B. Jungwirth; F. Pojer; M. Bussmann; V. A. Money et al. : The Crystal Structures of Apo and cAMP-Bound GlxR from Corynebacterium glutamicum Reveal Structural and Dynamic Changes upon cAMP Binding in CRP/FNR Family Transcription Factors; Plos One. 2014. DOI : 10.1371/journal.pone.0113265.
J. Fellay : Médecine génomique et Maladies infectieuses; Praxis. 2014. DOI : 10.1024/1661-8157/a001658.
P. Singh; A. Benjak; S. Carat; M. Kai; P. Busso et al. : Genome-wide re-sequencing of multidrug-resistant Mycobacterium leprae Airaku-3; Clinical Microbiology And Infection. 2014. DOI : 10.1111/1469-0691.12609.
D. L. Braun; R. Kouyos; C. Oberle; C. Grube; B. Joos et al. : A Novel Acute Retroviral Syndrome Severity Score Predicts the Key Surrogate Markers for HIV-1 Disease Progression; Plos One. 2014. DOI : 10.1371/journal.pone.0114111.
F. G. Van Der Goot; J. Gruenberg : Close Encounter of the Third Kind: The ER Meets Endosomes at Fission Sites; Developmental Cell. 2014. DOI : 10.1016/j.devcel.2014.12.008.
E. Berardi; D. Annibali; M. Cassano; S. Crippa; M. Sampaolesi : Molecular and cell-based therapies for muscle degenerations: a road under construction; Frontiers In Physiology. 2014. DOI : 10.3389/fphys.2014.00119.
M. Lo Scrudato; S. Borgeaud; M. Blokesch : Regulatory elements involved in the expression of competence genes in naturally transformable Vibrio cholerae; BMC microbiology. 2014. DOI : 10.1186/s12866-014-0327-y.
S. Sharma; E. Gelman; C. Narayan; D. Bhattacharjee; V. Achar et al. : Simple and Rapid Method To Determine Antimycobacterial Potency of Compounds by Using Autoluminescent Mycobacterium tuberculosis; Antimicrobial Agents And Chemotherapy. 2014. DOI : 10.1128/Aac.03205-14.
J. Rybniker; J. M. Chen; C. Sala; R. C. Hartkoorn; A. Vocat et al. : Anticytolytic Screen Identifies Inhibitors of Mycobacterial Virulence Protein Secretion; Cell Host & Microbe. 2014. DOI : 10.1016/j.chom.2014.09.008.
W.-B. A. Chng; M. S. B. Sleiman; F. Schuepfer; B. Lemaitre : Transforming Growth Factor beta/Activin Signaling Functions as a Sugar-Sensing Feedback Loop to Regulate Digestive Enzyme Expression; Cell Reports. 2014. DOI : 10.1016/j.celrep.2014.08.064.
J. Noack; M. Molinari : PROTEIN TRAFFICKING RESETting proteostasis; Nature Chemical Biology. 2014. DOI : 10.1038/nchembio.1652.
A. R. Wood; T. Esko; J. Yang; S. Vedantam; T. H. Pers et al. : Defining the role of common variation in the genomic and biological architecture of adult human height; Nature Genetics. 2014. DOI : 10.1038/ng.3097.
T. Chopra; R. Hamelin; F. Armand; D. Chiappe; M. Moniatte et al. : Quantitative Mass Spectrometry Reveals Plasticity of Metabolic Networks in Mycobacterium smegmatis; Molecular & Cellular Proteomics. 2014. DOI : 10.1074/mcp.M113.034082.
M. Bellinzoni; A. Haouz; I. Miras; S. Magnet; G. Andre-Leroux et al. : Structural studies suggest a peptidoglycan hydrolase function for the Mycobacterium tuberculosis Tat-secreted protein Rv2525c; Journal Of Structural Biology. 2014. DOI : 10.1016/j.jsb.2014.09.003.
D. Trono : Transposable elements and their epigenetic control mechanisms are key regulators of transcriptional networks in pluripotent stem cells. 2014. ESGCT and NVGCT Collaborative Congress, The Hague, NETHERLANDS, OCT 23-26, 2014. p. A11-A11.
G. Farinelli; M. Chiriaco; V. Capo; E. Zonari; M. Migliavacca et al. : Dual-Regulated Lentiviral Vector for Gene Therapy of X-linked Chronic Granulomatous Disease. 2014. ESGCT and NVGCT Collaborative Congress, The Hague, NETHERLANDS, OCT 23-26, 2014. p. A26-A26.
M. Imbeault; D. Trono : As Time Goes by: KRABs Evolve to KAP Endogenous Retroelements; Developmental Cell. 2014. DOI : 10.1016/j.devcel.2014.10.019.
P. Murima; J. D. Mckinney; K. Pethe : Targeting Bacterial Central Metabolism for Drug Development; Chemistry & Biology. 2014. DOI : 10.1016/j.chembiol.2014.08.020.
F. Boldrin; M. Ventura; G. Degiacomi; S. Ravishankar; C. Sala et al. : The Phosphatidyl-myo-Inositol Mannosyltransferase PimA Is Essential for Mycobacterium tuberculosis Growth In Vitro and In Vivo (vol 196, pg 3441, 2014); Journal Of Bacteriology. 2014. DOI : 10.1128/Jb.02332-14.
S. Geissbuehler; A. Sharipov; A. Godinat; N. L. Bocchio; P. A. Sandoz et al. : Live-cell multiplane three-dimensional super-resolution optical fluctuation imaging; Nature Communications. 2014. DOI : 10.1038/ncomms6830.
L. J. Steinbock; S. Krishnan; R. D. Bulushev; S. Borgeaud; M. Blokesch et al. : Probing the size of proteins with glass nanopores; Nanoscale. 2014. DOI : 10.1039/C4NR05001K.
J. Kühn; F. Finger; E. Bertuzzo; S. Borgeaud; M. Gatto et al. : Glucose- but Not Rice-Based Oral Rehydration Therapy Enhances the Production of Virulence Determinants in the Human Pathogen Vibrio cholerae; PLoS Neglected Tropical Diseases. 2014. DOI : 10.1371/journal.pntd.0003347.
G. S. Kolly : Genetic analysis of the decaprenyl-phospho-D-arabinofuranose pathway in Mycobacterium tuberculosis. Lausanne, EPFL, 2014. DOI : 10.5075/epfl-thesis-6352.
S. Chakrabarti; M. Poidevin; B. Lemaitre : The Drosophila MAPK p38c Regulates Oxidative Stress and Lipid Homeostasis in the Intestine; Plos Genetics. 2014. DOI : 10.1371/journal.pgen.1004659.
K. Yadava; J. Massacand; I. Mosconi; L. P. Nicod; N. L. Harris et al. : Thymic stromal lymphopoietin plays divergent roles in murine models of atopic and nonatopic airway inflammation; Allergy. 2014. DOI : 10.1111/all.12469.
J. Fellay : [Genomic medicine and infectious diseases]; Praxis. 2014. DOI : 10.1024/1661-8157/a001658.
N. Vince; A. A. Bashirova; A. Lied; X. Gao; L. Dorrell et al. : HLA class I and KIR genes do not protect against HIV type 1 infection in highly exposed uninfected individuals with hemophilia A; The Journal of infectious diseases. 2014. DOI : 10.1093/infdis/jiu214.
R. R. Regoes; P. J. McLaren; M. Battegay; E. Bernasconi; A. Calmy et al. : Disentangling human tolerance and resistance against HIV; PLoS biology. 2014. DOI : 10.1371/journal.pbio.1001951.
T. Dallavilla : Modelling of Protein Palmitoylation Networks ; ICSB 2014, Melbourne, Australia, 14-18 September.
V. Hornung; R. Hartmann; A. Ablasser; K.-P. Hopfner : OAS proteins and cGAS: unifying concepts in sensing and responding to cytosolic nucleic acids; Nature Reviews Immunology. 2014. DOI : 10.1038/nri3719.
V. V. Bockor; D. Barisic; T. Horvat; Z. Maglica; A. Vojta et al. : Inhibition of DNA Methylation Alters Chromatin Organization, Nuclear Positioning and Activity of 45S rDNA Loci in Cycling Cells of Q. robur; Plos One. 2014. DOI : 10.1371/journal.pone.0103954.
J. Noack; G. B. Pisoni; M. Molinari : Proteostasis: Bad news and good news from the endoplasmic reticulum; Swiss Medical Weekly. 2014. DOI : 10.4414/smw.2014.14001.
C. Gubelmann; P. C. Schwalie; S. K. Raghav; E. Roeder; T. Delessa et al. : Identification of the transcription factor ZEB1 as a central component of the adipogenic gene regulatory network; Elife. 2014. DOI : 10.7554/eLife.03346.
J. Noack; R. Bernasconi; M. Molinari : How Viruses Hijack the ERAD Tuning Machinery; Journal Of Virology. 2014. DOI : 10.1128/Jvi.00801-14.
C. Zaph; P. J. Cooper; N. L. Harris : Mucosal immune responses following intestinal nematode infection; Parasite Immunology. 2014. DOI : 10.1111/pim.12090.
M. Zhang; J. M. Chen; C. Sala; J. Rybniker; N. Dhar et al. : EspI regulates the ESX-1 secretion system in response to ATP levels in Mycobacterium tuberculosis; Molecular Microbiology. 2014. DOI : 10.1111/mmi.12718.
G. S. Kolly; C. Sala; A. Vocat; S. T. Cole : Assessing essentiality of transketolase in Mycobacterium tuberculosis using an inducible protein degradation system; Fems Microbiology Letters. 2014. DOI : 10.1111/1574-6968.12536.
F. Boldrin; M. Ventura; G. Degiacomi; S. Ravishankar; C. Sala et al. : The Phosphatidyl-myo-Inositol Mannosyltransferase PimA Is Essential for Mycobacterium tuberculosis Growth In Vitro and In Vivo; Journal Of Bacteriology. 2014. DOI : 10.1128/Jb.01346-13.
J. Fellay; J. L. Raisaro; Z. Huang; M. Humbert; E. Ayday et al. : Practical Solutions for Protecting Individual Genomic Privacy ; American Society of Human Genetics (ASHG), San Diego, CA, USA, October 2014.
P. Seitz; M. Blokesch : DNA Transport across the Outer and Inner Membranes of Naturally Transformable Vibrio cholerae Is Spatially but Not Temporally Coupled; mBio. 2014. DOI : 10.1128/mBio.01409-14.
V. Capo; G. Farinelli; M. Chiriaco; E. Zonari; S. Scaramuzza et al. : Dual-Regulated Lentiviral Vector for Gene Therapy of X-Linked Chronic Granulomatous Disease. 2014. 17th Annual Meeting of the American-Society-of-Gene-and-Cell-Therapy (ASGCT), Washington, DC, MAY 21-24, 2014. p. S261-S261.
L. Solans; J. Gonzalo-Asensio; C. Sala; A. Benjak; S. Uplekar et al. : The PhoP-Dependent ncRNA Mcr7 Modulates the TAT Secretion System in Mycobacterium tuberculosis; Plos Pathogens. 2014. DOI : 10.1371/journal.ppat.1004183.
P. Mohammadi; J. Di Iulio; M. Munoz; R. Martinez; I. Bartha et al. : Dynamics of HIV Latency and Reactivation in a Primary CD4+T Cell Model; Plos Pathogens. 2014. DOI : 10.1371/journal.ppat.1004156.
O. Binggeli; C. Neyen; M. Poidevin; B. Lemaitre : Prophenoloxidase Activation Is Required for Survival to Microbial Infections in Drosophila; Plos Pathogens. 2014. DOI : 10.1371/journal.ppat.1004067.
D. Osman; N. Buchon : The unsuspected complexity of the digestive tract of the fruitfly Towards a model of functional regionalization; M S-Medecine Sciences. 2014. DOI : 10.1051/medsci/20143005003.
N. A. Broderick; N. Buchon; B. Lemaitre : Microbiota-Induced Changes in Drosophila melanogaster Host Gene Expression and Gut Morphology; Mbio. 2014. DOI : 10.1128/mBio.01117-14.
B. Schnell; T. Staubli; N. L. Harris; G. Rogler; M. Kopf et al. : Cell-wall deficient L. monocytogenes L-forms feature abrogated pathogenicity; Frontiers In Cellular And Infection Microbiology. 2014. DOI : 10.3389/fcimb.2014.00060.
R. M. L. La Rovere; M. Quattrocelli; T. Pietrangelo; E. S. Di Filippo; L. Maccatrozzo et al. : Myogenic potential of canine craniofacial satellite cells; Frontiers In Aging Neuroscience. 2014. DOI : 10.3389/fnagi.2014.00090.
P. D. Leger; D. H. Johnson; G. K. Robbins; R. W. Shafer; D. B. Clifford et al. : Genome-wide association study of peripheral neuropathy with D-drug-containing regimens in AIDS Clinical Trials Group protocol 384; Journal Of Neurovirology. 2014. DOI : 10.1007/s13365-014-0235-9.
M. Zhang; C. Sala; N. Dhar; A. Vocat; V. K. Sambandamurthy et al. : In Vitro and In Vivo Activities of Three Oxazolidinones against Nonreplicating Mycobacterium tuberculosis; Antimicrobial Agents And Chemotherapy. 2014. DOI : 10.1128/Aac.02410-14.
C. Neyen; A. J. Bretscher; O. Binggeli; B. Lemaitre : Methods to study Drosophila immunity; Methods. 2014. DOI : 10.1016/j.ymeth.2014.02.023.
M. Naik; V. Humnabadkar; S. J. Tantry; M. Panda; A. Narayan et al. : 4-Aminoquinolone Piperidine Amides: Noncovalent Inhibitors of DprE1 with Long Residence Time and Potent Antimycobacterial Activity; Journal Of Medicinal Chemistry. 2014. DOI : 10.1021/jm5005978.
D. Albesa-Jove; L. R. Chiarelli; V. Makarov; M. R. Pasca; S. Urresti et al. : Rv2466c Mediates the Activation of TP053 To Kill Replicating and Non-replicating Mycobacterium tuberculosis; Acs Chemical Biology. 2014. DOI : 10.1021/cb500149m.
A. Rausell; P. Mohammadi; P. J. Mclaren; I. Bartha; I. Xenarios et al. : Analysis of Stop-Gain and Frameshift Variants in Human Innate Immunity Genes; Plos Computational Biology. 2014. DOI : 10.1371/journal.pcbi.1003757.
J. K. Herren; J. C. Paredes; F. Schuepfer; K. Arafah; P. Bulet et al. : Insect endosymbiont proliferation is limited by lipid availability; Elife. 2014. DOI : 10.7554/eLife.02964.
I. Mekterovic; D. Mekterovic; Z. Maglica : BactImAS: a platform for processing and analysis of bacterial time-lapse microscopy movies; Bmc Bioinformatics. 2014. DOI : 10.1186/1471-2105-15-251.
M. Chiriaco; G. Farinelli; V. Capo; E. Zonari; S. Scaramuzza et al. : Dual-regulated Lentiviral Vector for Gene Therapy of X-linked Chronic Granulomatosis; Molecular Therapy. 2014. DOI : 10.1038/mt.2014.87.
K. Mikusova; V. Makarov; J. Neres : DprE1-from the Discovery to the Promising Tuberculosis Drug Target; Current Pharmaceutical Design. 2014.
A. A. Bashirova; E. Martin-Gayo; D. C. Jones; Y. Qi; R. Apps et al. : LILRB2 Interaction with HLA Class I Correlates with Control of HIV-1 Infection; Plos Genetics. 2014. DOI : 10.1371/journal.pgen.1004196.
B. Lechartier : Benzothiazinones: from a new lead to new combination therapies against Mycobacterium tuberculosis. Lausanne, EPFL, 2014. DOI : 10.5075/epfl-thesis-6239.
S. Yan : In-Depth Analysis of Mutations in Hyaline Fibromatosis Syndrome (HFS). Lausanne, EPFL, 2014. DOI : 10.5075/epfl-thesis-6287.
J. C. Paredes Escobar : The useful gate-crasher. Lausanne, EPFL, 2014. DOI : 10.5075/epfl-thesis-6309.
N. Castro-Diaz; G. Ecco; A. Coluccio; A. Kapopoulou; B. Yazdanpanah et al. : Evolutionally dynamic L1 regulation in embryonic stem cells; Genes & development. 2014. DOI : 10.1101/gad.241661.114.
N. L. Harris; R. Pleass; J. M. Behnke : Understanding the role of antibodies in murine infections with Heligmosomoides (polygyrus) bakeri: 35 years ago, now and 35 years ahead; Parasite Immunology. 2014. DOI : 10.1111/pim.12057.
J. Rybniker; F. Pojer; J. Marienhagen; G. S. Kolly; J. M. Chen et al. : The cysteine desulfurase IscS of Mycobacterium tuberculosis is involved in iron sulfur cluster biogenesis and oxidative stress defence; Biochemical Journal. 2014. DOI : 10.1042/Bj20130732.
S. Blaskovic; A. Adibekian; M. Blanc; F. G. van der Goot : Mechanistic effects of protein palmitoylation and the cellular consequences thereof; Chemistry And Physics Of Lipids. 2014. DOI : 10.1016/j.chemphyslip.2014.02.001.
A. Bozec; M. M. Zaiss; R. Kagwiria; R. Voll; M. Rauh et al. : T Cell Costimulation Molecules CD80/86 Inhibit Osteoclast Differentiation by Inducing the IDO/Tryptophan Pathway; Science Translational Medicine. 2014. DOI : 10.1126/scitranslmed.3007764.
S. T. Cole : Who will develop new antibacterial agents?; Philosophical Transactions Of The Royal Society B-Biological Sciences. 2014. DOI : 10.1098/rstb.2013.0430.
P. Turelli; N. Castro-Diaz; F. Marzetta; A. Kapopoulou; C. Raclot et al. : Interplay of TRIM28 and DNA methylation in controlling human endogenous retroelements; Genome research. 2014. DOI : 10.1101/gr.172833.114.
M. Friedli; P. Turelli; A. Kapopoulou; B. Rauwel; N. Castro-Díaz et al. : Loss of transcriptional control over endogenous retroelements during reprogramming to pluripotency; Genome research. 2014. DOI : 10.1101/gr.172809.114.
G. S. Kolly; F. Boldrin; C. Sala; N. Dhar; R. C. Hartkoorn et al. : Assessing the essentiality of the decaprenyl-phospho-D-arabinofuranose pathway in Mycobacterium tuberculosis using conditional mutants; Molecular Microbiology. 2014. DOI : 10.1111/mmi.12546.
T. A. Mendum; V. J. Schuenemann; S. Roffey; G. M. Taylor; H. Wu et al. : Mycobacterium leprae genomes from a British medieval leprosy hospital: towards understanding an ancient epidemic; Bmc Genomics. 2014. DOI : 10.1186/1471-2164-15-270.
D. B. Sutherland; S. Fagarasan : Gut Reactions: Eosinophils Add another String to Their Bow; Immunity. 2014. DOI : 10.1016/j.immuni.2014.04.003.
R. C. Hartkoorn; S. Uplekar; S. T. Cole : Cross-Resistance between Clofazimine and Bedaquiline through Upregulation of MmpL5 in Mycobacterium tuberculosis; Antimicrobial Agents And Chemotherapy. 2014. DOI : 10.1128/Aac.00037-14.
R. C. Hartkoorn; O. B. Ryabova; L. R. Chiarelli; G. Riccardi; V. Makarov et al. : Mechanism of Action of 5-Nitrothiophenes against Mycobacterium tuberculosis; Antimicrobial Agents And Chemotherapy. 2014. DOI : 10.1128/Aac.02693-13.
K. Li; L. A. Schurig-Briccio; X. Feng; A. Upadhyay; V. Pujari et al. : Multitarget Drug Discovery for Tuberculosis and Other Infectious Diseases; Journal Of Medicinal Chemistry. 2014. DOI : 10.1021/jm500131s.
M. Elitas; R. Martinez-Duarte; N. Dhar; J. D. Mckinney; P. Renaud : Dielectrophoresis-based purification of antibiotic-treated bacterial subpopulations; Lab on a Chip. 2014. DOI : 10.1039/c4lc00109e.
A. Ablasser; I. Hemmerling; J. L. Schmid-Burgk; R. Behrendt; A. Roers et al. : TREX1 Deficiency Triggers Cell-Autonomous Immunity in a cGAS-Dependent Manner; Journal of immunology. 2014. DOI : 10.4049/jimmunol.1400737.
P. M. Seitz : Mechanistic aspects of DNA uptake in naturally competent Vibrio cholerae. Lausanne, EPFL, 2014. DOI : 10.5075/epfl-thesis-6164.
I. Mosconi : Regulatory T cells modulate the intestinal immune response in homeostasis and infection. Lausanne, EPFL, 2014. DOI : 10.5075/epfl-thesis-6141.
I. Bartha; P. J. Mclaren; A. Ciuffi; J. Fellay; A. Telenti : GuavaH: a compendium of host genomic data in HIV biology and disease; Retrovirology. 2014. DOI : 10.1186/1742-4690-11-6.
A. Koul; L. Vranckx; N. Dhar; H. W. H. Gohlmann; M. E. Özdemir et al. : Delayed bactericidal response of Mycobacterium tuberculosis to bedaquiline involves remodelling of bacterial metabolism; Nature Communications. 2014. DOI : 10.1038/ncomms4369.
S. Surade; N. Ty; N. Hengrung; B. Lechartier; S. T. Cole et al. : A structure-guided fragment-based approach for the discovery of allosteric inhibitors targeting the lipophilic binding site of transcription factor EthR; Biochemical Journal. 2014. DOI : 10.1042/Bj20131127.
D. H. Johnson; C. Venuto; M. D. Ritchie; G. D. Morse; E. S. Daar et al. : Genomewide association study of atazanavir pharmacokinetics and hyperbilirubinemia in AIDS Clinical Trials Group protocol A5202; Pharmacogenetics And Genomics. 2014. DOI : 10.1097/Fpc.0000000000000034.
A. I. Zumla; S. H. Gillespie; M. Hoelscher; P. P. J. Philips; S. T. Cole et al. : New antituberculosis drugs, regimens, and adjunct therapies: needs, advances, and future prospects; Lancet Infectious Diseases. 2014. DOI : 10.1016/S1473-3099(13)70328-1.
V. Makarov; B. Lechartier; M. Zhang; J. de Almeida Neres; J. Pedro et al. : Towards a new combination therapy for tuberculosis with next generation benzothiazinones; Embo Molecular Medicine. 2014. DOI : 10.1002/emmm.201303575.
D. E. Minnikin; G. M. Taylor; G. R. Stewart; T. A. Mendum; S. Roffey et al. : Defining the origins and spread of leprosy using molecular biomarkers. 2014. 83rd Annual Meeting of the American-Association-of-Physical-Anthropologists. p. 186-187.
G. Manina; J. D. McKinney : A Single-Cell Perspective on Non-Growing but Metabolically Active (NGMA) Bacteria; Pathogenesis Of Mycobacterium Tuberculosis And Its Interaction With The Host Organism; Berlin: Springer-Verlag, 2014. p. 135-161.
J. Pieters; J. McKinney : Pathogenesis of Mycobacterium tuberculosis and its Interaction with the Host Organism Preface; Pathogenesis Of Mycobacterium Tuberculosis And Its Interaction With The Host Organism; Berlin: Springer-Verlag, 2014. p. V-VI.
I. Barde; B. Rauwel; R. M. Marin-Florez; A. Corsinotti; E. Laurenti et al. : Control of mitophagie by microRNAs - A key step of erythropoiesis; M S-Medecine Sciences. 2014.
S. Kicka; V. Trofimov; C. Harrison; H. Ouertatani-Sakouhi; J. McKinney et al. : Establishment and Validation of Whole-Cell Based Fluorescence Assays to Identify Anti-Mycobacterial Compounds Using the Acanthamoeba castellanii - Mycobacterium marinum Host-Pathogen System; Plos One. 2014. DOI : 10.1371/journal.pone.0087834.
R. C. Hartkoorn; F. Pojer; J. A. Read; H. Gingell; J. Neres et al. : Pyridomycin bridges the NADH- and substratebinding pockets of the enoyl reductase InhA; Nature Chemical Biology. 2014.
B. Lechartier; J. Rybniker; A. Zumla; S. T. Cole : Tuberculosis drug discovery in the post-post-genomic era; Embo Molecular Medicine. 2014. DOI : 10.1002/emmm.201201772.
E. Gelman : Antibiotic-Induced Killing and Persistence of Mycobacteria. Lausanne, EPFL, 2014. DOI : 10.5075/epfl-thesis-6056.
C. S. Smith; S. K. Noordeen; J. H. Richardus; H. Sansarricq; S. T. Cole et al. : A strategy to halt leprosy transmission; Lancet Infectious Diseases. 2014.
J. K. Herren : The Effectual Hitchhiker. Lausanne, EPFL, 2014. DOI : 10.5075/epfl-thesis-6079.
L. C. Metzger; M. Blokesch : Composition of the DNA-uptake complex of Vibrio cholerae; Mobile Genetic Elements. 2014. DOI : 10.4161/mge.28142.
D. L. Boyle; D. Hammaker; M. Edgar; M. M. Zaiss; S. Teufel et al. : Differential Roles of MAPK Kinases MKK3 and MKK6 in Osteoclastogenesis and Bone Loss; Plos One. 2014. DOI : 10.1371/journal.pone.0084818.
M. Lo Scrudato : The regulatory circuit of natural competence for transformation in the human pathogen Vibrio cholerae. Lausanne, EPFL, 2014. DOI : 10.5075/epfl-thesis-6078.
A. Trompette; E. S. Gollwitzer; K. Yadava; A. K. Sichelstiel; N. Sprenger et al. : Gut microbiota metabolism of dietary fiber influences allergic airway disease and hematopoiesis; Nature medicine. 2014. DOI : 10.1038/nm.3444.
B. Blasco : Structure-function analysis of the EspR virulence regulator of Mycobacterium tuberculosis. Lausanne, EPFL, 2014. DOI : 10.5075/epfl-thesis-6000.
P. Seitz; H. Pezeshgi Modarres; S. Borgeaud; R. D. Bulushev; L. J. Steinbock et al. : ComEA Is Essential for the Transfer of External DNA into the Periplasm in Naturally Transformable Vibrio cholerae Cells; PLoS Genetics. 2014. DOI : 10.1371/journal.pgen.1004066.
S. Blaskovic : Mechanism and Function of S-palmitoylation in Capillary Morphogenesis Gene 2. Lausanne, EPFL, 2014. DOI : 10.5075/epfl-thesis-6027.


M. Salathé; C. C. Freifeld; S. R. Mekaru; A. F. Tomasulo; J. S. Brownstein : Influenza A (H7N9) and the importance of digital epidemiology; The New England journal of medicine. 2013. DOI : 10.1056/NEJMp1307752.
M. Salathé; D. Vu; S. Khandelwal; D. Hunter : The dynamics of health behavior sentiments on a large online social network; EPJ Data Science. 2013. DOI : 10.1140/epjds16.
T. Bodnar; M. Salathé : Validating models for disease detection using twitter. 2013. 22nd International World Wide Web Conference (WWW 2013), Rio de Janeiro, Brazil, May 13 - 17, 2013. p. 699-702.
E. Campbell; M. Salathé : Complex social contagion makes networks more vulnerable to disease outbreaks; Scientific reports. 2013. DOI : 10.1038/srep01905.
T. Smieszek; M. Salathé : A low-cost method to assess the epidemiological importance of individuals in controlling infectious disease outbreaks; BMC medicine. 2013. DOI : 10.1186/1741-7015-11-35.
S. Tuarob; C. Tucker; M. Salathé; N. Ram : Discovering health-related knowledge in social media using ensembles of heterogeneous features. 2013. 22nd ACM international conference on Information & Knowledge Management (CIKM 2013), San Francisco, CA, USA, October 27 - November 01, 2013. p. 1685-1690. DOI : 10.1145/2505515.2505629.
Z. Huang; U. Kumar; T. Bodnar; M. Salathé : Understanding population displacements on location-based call records using road data. 2013. 21st ACM SIGSPATIAL International Conference on Advances in Geographic Information Systems (ACM SIGSPATIAL GIS 2013), Orlando, Florida, USA, November 5-8, 2013. p. 17-21.
H. Xia; J. Chen; M. Marathe; H. Mortveit; M. Salathé : Synthesizing Social Proximity Networks by Combining Subjective Surveys with Digital Traces. 2013. IEEE 16th International Conference on Computational Science and Engineering (CSE), Sydney, Australia, December 03-05, 2013. p. 188-195. DOI : 10.1109/CSE.2013.38.
T. Bodnar; M. Salathé : The Social Maintenance of Cooperation through Hypocrisy; arXiv. 2013.
P. J. McLaren; J. Fellay; A. Telenti : European genetic diversity and susceptibility to pathogens; Human heredity. 2013. DOI : 10.1159/000357758.
M. Carrington; A. A. Bashirova; P. J. Mclaren : On stand by: host genetics of HIV control; Aids. 2013. DOI : 10.1097/01.aids.0000432536.85335.c8.
F. Martinon; F. G. van der Goot : Did Cholera Toxin Finally Get Caught?; Cell Host & Microbe. 2013. DOI : 10.1016/j.chom.2013.04.014.
A. Ablasser; V. Hornung : DNA sensing unchained; Cell research. 2013. DOI : 10.1038/cr.2013.28.
A. Ablasser; C. Hertrich; R. Waßermann; V. Hornung : Nucleic acid driven sterile inflammation; Clinical immunology (Orlando, Fla.). 2013. DOI : 10.1016/j.clim.2013.01.003.
T. Cavlar; T. Deimling; A. Ablasser; K.-P. Hopfner; V. Hornung : Species-specific detection of the antiviral small-molecule compound CMA by STING; The EMBO journal. 2013. DOI : 10.1038/emboj.2013.86.
A. Ablasser; M. Goldeck; T. Cavlar; T. Deimling; G. Witte et al. : cGAS produces a 2'-5'-linked cyclic dinucleotide second messenger that activates STING; Nature. 2013. DOI : 10.1038/nature12306.
F. Civril; T. Deimling; C. C. de Oliveira Mann; A. Ablasser; M. Moldt et al. : Structural mechanism of cytosolic DNA sensing by cGAS; Nature. 2013. DOI : 10.1038/nature12305.
A. Ablasser; J. L. Schmid-Burgk; I. Hemmerling; G. L. Horvath; T. Schmidt et al. : Cell intrinsic immunity spreads to bystander cells via the intercellular transfer of cGAMP; Nature. 2013. DOI : 10.1038/nature12640.
S. Kim; V. Kaiser; E. Beier; M. Bechheim; M. Guenthner-Biller et al. : Self-priming determines high type I IFN production by plasmacytoid dendritic cells; European journal of immunology. 2013. DOI : 10.1002/eji.201343806.
L. Abrami; L. Brandi; M. Moayeri; M. J. Brown; B. A. Krantz et al. : Hijacking Multivesicular Bodies Enables Long-Term and Exosome-Mediated Long-Distance Action of Anthrax Toxin; Cell Reports. 2013. DOI : 10.1016/j.celrep.2013.10.019.
V. Makarov; S. Cole : New Generation Benzothiazinones For Tuberculosis Therapy. 2013. p. 79-79.
I. Bartha; M. Assel; P. M. A. Sloot; M. Zazzi; C. Torti et al. : Superinfection with drug-resistant HIV is rare and does not contribute substantially to therapy failure in a large European cohort; Bmc Infectious Diseases. 2013. DOI : 10.1186/1471-2334-13-537.
R. Bernasconi; C. Galli; K. Kokame; M. Molinari : Autoadaptive ER-Associated Degradation Defines a Preemptive Unfolded Protein Response Pathway; Molecular Cell. 2013. DOI : 10.1016/j.molcel.2013.10.016.
I. Bartha; J. M. Carlson; C. J. Brumme; P. J. Mclaren; Z. L. Brumme et al. : A genome-to-genome analysis of associations between human genetic variation, HIV-1 sequence diversity, and viral control; Elife. 2013. DOI : 10.7554/eLife.01123.
C. Van Der Henst; M. De Barsy; A. Zorreguieta; J.-J. Letesson; X. De Bolle : The Brucella pathogens are polarized bacteria; Microbes And Infection. 2013. DOI : 10.1016/j.micinf.2013.10.008.
J. M. Chen; M. Zhang; J. Rybniker; L. Basterra; N. Dhar et al. : Phenotypic Profiling of Mycobacterium tuberculosis EspA Point Mutants Reveals that Blockage of ESAT-6 and CFP-10 Secretion In Vitro Does Not Always Correlate with Attenuation of Virulence; Journal Of Bacteriology. 2013. DOI : 10.1128/Jb.00967-13.
C. Pokalyuk; L. A. Mathew; D. Metzler; P. Pfaffelhuber : Competing islands limit the rate of adaptation in structured populations; Theoretical Population Biology. 2013. DOI : 10.1016/j.tpb.2013.08.001.
S. Kulkarni; Y. Qi; C. O'Huigin; F. Pereyra; V. Ramsuran et al. : Genetic interplay between HLA-C and MIR148A in HIV control and Crohn disease; Proceedings Of The National Academy Of Sciences Of The United States Of America. 2013. DOI : 10.1073/pnas.1312237110.
B. Lemaitre; I. Miguel-Aliaga : The Digestive Tract of Drosophila melanogaster; Annual review of genetics. 2013. DOI : 10.1146/annurev-genet-111212-133343.
L. A. Mathew; P. R. Staab; L. E. Rose; D. Metzler : Why to account for finite sites in population genetic studies and how to do this with Jaatha 2.0; Ecology And Evolution. 2013. DOI : 10.1002/ece3.722.
J. M. Rutkowski; J. E. Ihm; S. T. Lee; W. W. Kilarski; V. I. Greenwood et al. : VEGFR-3 Neutralization Inhibits Ovarian Lymphangiogenesis, Follicle Maturation, and Murine Pregnancy; American Journal Of Pathology. 2013. DOI : 10.1016/j.ajpath.2013.07.031.
P. Paganetti; J. Reichwald; D. Bleckmann; D. Abramowski; D. Ammaturo et al. : Transgenic expression of beta 1 antibody in brain neurons impairs age-dependent amyloid deposition in APP23 mice; Neurobiology Of Aging. 2013. DOI : 10.1016/j.neurobiolaging.2013.06.013.
J. Esser-von Bieren; I. Mosconi; R. Guiet; A. Piersigilli; B. Volpe et al. : Antibodies Trap Tissue Migrating Helminth Larvae and Prevent Tissue Damage by Driving IL-4Rα-Independent Alternative Differentiation of Macrophages; Plos Pathogens. 2013. DOI : 10.1371/journal.ppat.1003771.
M. E. Özdemir : Metabolic modeling and experimental studies on carbon and energy metabolism of Mycobacterium tuberculosis. Lausanne, EPFL, 2013. DOI : 10.5075/epfl-thesis-5970.
J. M. Chen; M. Zhang; J. Rybniker; S. Boy-Röttger; N. Dhar et al. : Mycobacterium tuberculosis EspB binds phospholipids and mediates EsxA-independent virulence; Molecular Microbiology. 2013. DOI : 10.1111/mmi.12336.
S. P. Ferris; N. S. Jaber; M. Molinari; P. Arvan; R. J. Kaufman : UDP-glucose:glycoprotein glucosyltransferase (UGGT1) promotes substrate solubility in the endoplasmic reticulum; Molecular Biology Of The Cell. 2013. DOI : 10.1091/mbc.E13-02-0101.
L. Westera; J. Drylewicz; I. Den Braber; T. Mugwagwa; I. Van Der Maas et al. : Closing the gap between T-cell life span estimates from stable isotope-labeling studies in mice and humans; Blood. 2013. DOI : 10.1182/blood-2013-03-488411.
M. T. Degiacomi; I. Lacovache; L. Pernot; M. Chami; M. Kudryashev et al. : Molecular assembly of the aerolysin pore reveals a swirling membrane-insertion mechanism; Nature Chemical Biology. 2013. DOI : 10.1038/Nchembio.1312.
G. Riccardi; M. R. Pasca; L. R. Chiarelli; G. Manina; A. Mattevi et al. : The DprE1 enzyme, one of the most vulnerable targets of Mycobacterium tuberculosis; Applied Microbiology And Biotechnology. 2013. DOI : 10.1007/s00253-013-5218-x.
P. Seitz; M. Blokesch : DNA-uptake machinery of naturally competent Vibrio cholerae; Proceedings of the National Academy of Sciences of the United States of America. 2013. DOI : 10.1073/pnas.1315647110.
J. Merulla; E. Fasana; T. Solda; M. Molinari : Specificity and Regulation of the Endoplasmic Reticulum-Associated Degradation Machinery; Traffic. 2013. DOI : 10.1111/tra.12068.
M. Gendrin; A. Zaidman-Remy; N. A. Broderick; J. Paredes; M. Poidevin et al. : Functional Analysis of PGRP-LA in Drosophila Immunity; Plos One. 2013. DOI : 10.1371/journal.pone.0069742.
N. Q. Balaban; K. Gerdes; K. Lewis; J. D. McKinney : A problem of persistence: still more questions than answers?; Nature Reviews Microbiology. 2013. DOI : 10.1038/nrmicro3076.
M. Blemont; R. Vincentelli; C. Kellenberger; O. Opota; B. Lemaitre et al. : Crystallization and preliminary X-ray analysis of monalysin, a novel beta-pore-forming toxin from the entomopathogen Pseudomonas entomophila; Acta Crystallographica Section F-Structural Biology And Crystallization Communications. 2013. DOI : 10.1107/S174430911301885X.
A. K. Lakkaraju; G. van der Goot : Calnexin Controls the STAT3-Mediated Transcriptional Response to EGF; Molecular Cell. 2013. DOI : 10.1016/j.molcel.2013.07.009.
N. Buchon; N. A. Broderick; B. Lemaitre : Gut homeostasis in a microbial world: insights from Drosophila melanogaster; Nature Reviews Microbiology. 2013. DOI : 10.1038/nrmicro3074.
G. M. Taylor; K. Tucker; R. Butler; A. W. G. Pike; J. Lewis et al. : Detection and Strain Typing of Ancient Mycobacterium leprae from a Medieval Leprosy Hospital; Plos One. 2013. DOI : 10.1371/journal.pone.0062406.
A. Zumla; P. Nahid; S. T. Cole : Advances in the development of new tuberculosis drugs and treatment regimens; Nature Reviews Drug Discovery. 2013. DOI : 10.1038/nrd4001.
N. Buchon; D. Osman; F. P. A. David; H. Y. Fang; J.-P. Boquete et al. : Morphological and Molecular Characterization of Adult Midgut Compartmentalization in Drosophila (vol 3, pg 1725, 2013); Cell Reports. 2013. DOI : 10.1016/j.celrep.2013.05.019.
N. Buchon; D. Osman; F. P. A. David; H. Y. Fang; J.-P. Boquete et al. : Morphological and Molecular Characterization of Adult Midgut Compartmentalization in Drosophila; Cell Reports. 2013. DOI : 10.1016/j.celrep.2013.04.001.
E. J. Possik; M. S. B. Sleiman; I. R. Ghattas; C. A. Smith : Randomized codon mutagenesis reveals that the HIV Rev arginine-rich motif is robust to substitutions and that double substitution of two critical residues alters specificity; Journal Of Molecular Recognition. 2013. DOI : 10.1002/jmr.2272.
B. Lemaitre; S. E. Girardin : Translation inhibition and metabolic stress pathways in the host response to bacterial pathogens; Nature Reviews Microbiology. 2013. DOI : 10.1038/nrmicro3029.
J. Vanhomwegen; N. Berthet; C. Mazuet; G. Guigon; T. Vallaeys et al. : Application of High-Density DNA Resequencing Microarray for Detection and Characterization of Botulinum Neurotoxin-Producing Clostridia; Plos One. 2013. DOI : 10.1371/journal.pone.0067510.
B. Di Palo; V. Rippa; I. Santi; C. Brettoni; A. Muzzi et al. : Adaptive Response of Group B Streptococcus to High Glucose Conditions: New Insights on the CovRS Regulation Network; Plos One. 2013. DOI : 10.1371/journal.pone.0061294.
I. Santi; N. Dhar; D. Bousbaine; Y. Wakamoto; J. D. McKinney : Single-cell dynamics of the chromosome replication and cell division cycles in mycobacteria; Nature Communications. 2013. DOI : 10.1038/ncomms3470.
C. De Piano : The Phosphate Specific Transport (Pst) System in Fast- and Slow-Growing Mycobacteria. Lausanne, EPFL, 2013. DOI : 10.5075/epfl-thesis-5885.
V. J. Schuenemann; P. Singh; T. A. Mendum; B. Krause-Kyora; G. Jäger et al. : Genome-wide comparison of medieval and modern Mycobacterium leprae; Science (New York, N.Y.). 2013. DOI : 10.1126/science.1238286.
O. Binggeli : Role and regulation of the melanization reaction in Drosophila immune response. Lausanne, EPFL, 2013. DOI : 10.5075/epfl-thesis-5840.
S. Chakrabarti : The contribution of the host stress response to the pathogenesis of Pseudomonas entomophila in the Drosophila intestine. Lausanne, EPFL, 2013. DOI : 10.5075/epfl-thesis-5794.
E. Ayday; J. L. Raisaro; M. Laren; P. Jack; J. Fellay et al. : Privacy-Preserving Computation of Disease Risk by Using Genomic, Clinical, and Environmental Data (poster version) ; USENIX Security Workshop on Health Information Technologies (HealthTech '13), Washington, DC, USA, August, 2013.
S. Blaskovic; M. Blanc; G. van der Goot : What does S-palmitoylation do to membrane proteins?; The FEBS journal. 2013. DOI : 10.1111/febs.12263.
J. Lane; P. J. Mclaren; L. Dorrell; K. V. Shianna; A. Stemke et al. : A genome-wide association study of resistance to HIV infection in highly exposed uninfected individuals with hemophilia A; Human Molecular Genetics. 2013. DOI : 10.1093/hmg/ddt033.
M. Rotger; T. R. Glass; T. Junier; J. Lundgren; J. D. Neaton et al. : Contribution of Genetic Background, Traditional Risk Factors, and HIV-Related Factors to Coronary Artery Disease Events in HIV-Positive Persons; Clinical Infectious Diseases. 2013. DOI : 10.1093/cid/cit196.
P. J. Mclaren; C. Coulonges; S. Ripke; L. Van Den Berg; S. Buchbinder et al. : Association Study of Common Genetic Variants and HIV-1 Acquisition in 6,300 Infected Cases and 7,200 Controls; PLoS Pathogens. 2013. DOI : 10.1371/journal.ppat.1003515.
S. E. Yan; T. Lemmin; S. Salvi; E. Lausch; A. Superti-Furga et al. : In-depth analysis of hyaline fibromatosis syndrome frameshift mutations at the same site reveal the necessity of personalized therapy; Human mutation. 2013. DOI : 10.1002/humu.22324.
M. Zhang : Novel strategies for the development of anti-tuberculosis compounds. Lausanne, EPFL, 2013. DOI : 10.5075/epfl-thesis-5838.
T. Venkova-Canova; J. H. Baek; P. C. Fitzgerald; M. Blokesch; D. K. Chattoraj : Evidence for Two Different Regulatory Mechanisms Linking Replication and Segregation of Vibrio cholerae Chromosome II; PLoS Genetics. 2013. DOI : 10.1371/journal.pgen.1003579.
J. Vasudevan; A. Ayyappan; M. Perkovic; Y. Bulliard; K. Cichutek et al. : Prototype Foamy Virus Bet Impairs the Dimerization and Cytosolic Solubility of Human APOBEC3G; Journal of virology. 2013. DOI : 10.1128/JVI.03385-12.
M. M. Zaiss; K. M. Maslowski; I. Mosconi; N. Guenat; B. J. Marsland et al. : IL-1β Suppresses Innate IL-25 and IL-33 Production and Maintains Helminth Chronicity; PLoS pathogens. 2013. DOI : 10.1371/journal.ppat.1003531.
E. Ayday; J. L. Raisaro; M. Laren; P. Jack; J. Fellay et al. : Privacy-Preserving Computation of Disease Risk by Using Genomic, Clinical, and Environmental Data. 2013. USENIX Security Workshop on Health Information Technologies (HealthTech '13), Washington, DC, USA, August.
G. Andrey; T. Montavon; B. Mascrez; F. Gonzalez; D. Noordermeer et al. : A switch between topological domains underlies HoxD genes collinearity in mouse limbs; Science (New York, N.Y.). 2013. DOI : 10.1126/science.1234167.
H. Haruki; M. G. Pedersen; K. I. Gorska; F. Pojer; K. Johnsson : Tetrahydrobiopterin Biosynthesis as an Off-Target of Sulfa Drugs; Science. 2013. DOI : 10.1126/science.1232972.
I. Mosconi; M. B. Geuking; M. M. Zaiss; J. C. Massacand; C. Aschwanden et al. : Intestinal bacteria induce TSLP to promote mutualistic T-cell responses; Mucosal Immunology. 2013. DOI : 10.1038/mi.2013.12.
A. K. Gloudemans; M. Plantinga; M. Guilliams; M. A. Willart; A. Ozir-Fazalalikhan et al. : The Mucosal Adjuvant Cholera Toxin B Instructs Non-Mucosal Dendritic Cells to Promote IgA Production Via Retinoic Acid and TGF-β; PLoS ONE. 2013. DOI : 10.1371/journal.pone.0059822.
K. Gopinath; C. Venclovas; T. R. Ioerger; J. C. Sacchettini; J. D. McKinney et al. : A vitamin B-12 transporter in Mycobacterium tuberculosis; Open Biology. 2013. DOI : 10.1098/rsob.120175.
R. Apps; Y. Qi; J. M. Carlson; H. Chen; X. Gao et al. : Influence of HLA-C Expression Level on HIV Control; Science. 2013. DOI : 10.1126/science.1232685.
M. Degiacomi; I. Iacovache; G. Van Der Goot; M. Dal Peraro : The Molecular Assembly of the Aerolysin Pore Reveals a Unique Swirling Membrane-Insertion Mechanism. 2013. 57th Annual Meeting of the Biophysical-Society. p. 395A-395A.
J. K. Herren; J. C. Paredes; F. Schüpfer; B. Lemaitre : Vertical transmission of a Drosophila endosymbiont via cooption of the yolk transport and internalization machinery; mBio. 2013. DOI : 10.1128/mBio.00532-12.
R. Aparicio; C. Neyen; B. Lemaitre; A. Busturia : dRYBP Contributes to the Negative Regulation of the Drosophila Imd Pathway; PloS one. 2013. DOI : 10.1371/journal.pone.0062052.
X. L. Guan; G. Cestra; G. Shui; A. Kuhrs; R. B. Schittenhelm et al. : Biochemical Membrane Lipidomics during Drosophila Development; Developmental Cell. 2013. DOI : 10.1016/j.devcel.2012.11.012.
A. D. Tischler; R. L. Leistikow; M. A. Kirksey; M. I. Voskuil; J. D. McKinney : Mycobacterium tuberculosis Requires Phosphate-Responsive Gene Regulation To Resist Host Immunity; Infection And Immunity. 2013. DOI : 10.1128/Iai.01136-12.
I. Abubakar; M. Zignol; D. Falzon; M. Raviglione; L. Ditiu et al. : Drug-resistant tuberculosis: time for visionary political leadership; The Lancet Infectious Diseases. 2013. DOI : 10.1016/S1473-3099(13)70030-6.
R. S. Wallis; P. Kim; S. Cole; D. Hanna; B. B. Andrade et al. : Tuberculosis biomarkers discovery: developments, needs, and challenges; The Lancet infectious diseases. 2013. DOI : 10.1016/S1473-3099(13)70034-3.
I. Castanon; L. Abrami; L. Holtzer; C. P. Heisenberg; G. van der Goot et al. : Anthrax toxin receptor 2a controls mitotic spindle positioning; Nature Cell Biology. 2013. DOI : 10.1038/ncb2632.
S. Uplekar; J. Rougemont; S. T. Cole; C. Sala : High-resolution transcriptome and genome-wide dynamics of RNA polymerase and NusA in Mycobacterium tuberculosis; Nucleic Acids Research. 2013. DOI : 10.1093/nar/gks1260.
R. A. Slayden; M. Jackson; J. Zucker; M. V. Ramirez; C. C. Dawson et al. : Updating and curating metabolic pathways of TB; Tuberculosis. 2013. DOI : 10.1016/
J. M. Lew; C. Mao; M. Shukla; A. Warren; R. Will et al. : Database resources for the tuberculosis community; Tuberculosis. 2013. DOI : 10.1016/
B. Jungwirth; C. Sala; T. A. Kohl; S. Uplekar; J. Baumbach et al. : High-resolution detection of DNA binding sites of the global transcriptional regulator GlxR in Corynebacterium glutamicum; Microbiology-Sgm. 2013. DOI : 10.1099/mic.0.062059-0.
M. Blanc; S. Blaskovic; V. D. Goot; F. Gisou : Palmitoylation, pathogens and their host; Biochemical Society Transactions. 2013. DOI : 10.1042/Bst20120337.
O. P. Horlacher; R. C. Hartkoorn; S. T. Cole; K.-H. Altmann : Synthesis and Antimycobacterial Activity of 2,1 '-Dihydropyridomycins; Acs Medicinal Chemistry Letters. 2013. DOI : 10.1021/ml300385q.
Y. Wakamoto; N. Dhar; R. Chait; K. E. Schneider; F. Signorino-Gelo et al. : Dynamic Persistence of Antibiotic-Stressed Mycobacteria; Science. 2013. DOI : 10.1126/science.1229858.
A. Corsinotti; A. Kapopoulou; C. Gubelmann; M. Imbeault; S. de Sio et al. : Global and stage specific patterns of krüppel-associated-box zinc finger protein gene expression in murine early embryonic cells; PloS one. 2013. DOI : 10.1371/journal.pone.0056721.
C. Hornung; A. Poehlein; F. S. Haack; M. Schmidt; K. Dierking et al. : The Janthinobacterium sp. HH01 Genome Encodes a Homologue of the V. cholerae CqsA and L. pneumophila LqsA Autoinducer Synthases; PLoS ONE. 2013. DOI : 10.1371/journal.pone.0055045.
M. Lo Scrudato; M. Blokesch : A transcriptional regulator linking quorum sensing and chitin induction to render Vibrio cholerae naturally transformable; Nucleic acids research. 2013. DOI : 10.1093/nar/gkt041.
C. Márquez; G. L. Poirier; M. I. Cordero; M. H. Larsen; A. Groner et al. : Peripuberty stress leads to abnormal aggression, altered amygdala and orbitofrontal reactivity and increased prefrontal MAOA gene expression; Transl Psychiatry. 2013. DOI : 10.1038/tp.2012.144.
S. Borgeaud; M. Blokesch : Overexpression of the tcp Gene Cluster Using the T7 RNA Polymerase/Promoter System and Natural Transformation-Mediated Genetic Engineering of Vibrio cholerae; PLoS ONE. 2013. DOI : 10.1371/journal.pone.0053952.
H. M. Rowe; M. Friedli; S. Offner; S. Verp; D. Mesnard et al. : De novo DNA methylation of endogenous retroviruses is shaped by KRAB-ZFPs/KAP1 and ESET; Development (Cambridge, England). 2013. DOI : 10.1242/dev.087585.
H. M. Rowe; A. Kapopoulou; A. Corsinotti; L. Fasching; T. S. Macfarlan et al. : TRIM28 repression of retrotransposon-based enhancers is necessary to preserve transcriptional dynamics in embryonic stem cells; Genome research. 2013. DOI : 10.1101/gr.147678.112.
P. Seitz; M. Blokesch : Cues and regulatory pathways involved in natural competence and transformation in pathogenic and environmental Gram-negative bacteria; FEMS Microbiology Reviews. 2013. DOI : 10.1111/j.1574-6976.2012.00353.x.
K. Yadava; A. Sichelstiel; I. F. Luescher; L. P. Nicod; N. L. Harris et al. : TSLP promotes influenza-specific CD8+ T-cell responses by augmenting local inflammatory dendritic cell function; Mucosal immunology. 2013. DOI : 10.1038/mi.2012.50.


M. Salathé; L. Bengtsson; T. J. Bodnar; D. D. Brewer; J. S. Brownstein et al. : Digital epidemiology; PLoS computational biology. 2012. DOI : 10.1371/journal.pcbi.1002616.
R. Mostowy; J. Engelstädter; M. Salathé : Non-genetic inheritance and the patterns of antagonistic coevolution; BMC evolutionary biology. 2012. DOI : 10.1186/1471-2148-12-93.
T. Bodnar; M. Salathé : Governing the global commons with local institutions; PloS one. 2012. DOI : 10.1371/journal.pone.0034051.
V. Makarov; S. Cole ; 2-piperazin-1-yl-4h-1,3-benzothiazin-4-one derivatives and their use for the treatment of mammalian infections. CA2817931 ; CN107011287 ; AU2011330742 ; GEP201606545 ; IL226289 ; US8796264 ; KR20140012956 ; ZA201303829 ; EP2640712 ; US2013245007 ; CN103221399 ; AU2011330742 ; CA2817931 ; WO2012066518 ; EA023879 . 2012.
T. Cavlar; A. Ablasser; V. Hornung : Induction of type I IFNs by intracellular DNA-sensing pathways; Immunology and cell biology. 2012. DOI : 10.1038/icb.2012.11.
S. K. Pillai; M. Abdel-Mohsen; J. Guatelli; M. Skasko; A. Monto et al. : Role of retroviral restriction factors in the interferon- -mediated suppression of HIV-1 in vivo; Proceedings of the National Academy of Sciences. 2012. DOI : 10.1073/pnas.1111573109.
M. Stern; K. Czaja; A. Rauch; M. Rickenbach; H. F. Günthard et al. : HLA-Bw4 identifies a population of HIV-infected patients with an increased capacity to control viral replication after structured treatment interruption; HIV Medicine. 2012. DOI : 10.1111/j.1468-1293.2012.01019.x.
M. Blokesch : A quorum sensing-mediated switch contributes to natural transformation of Vibrio cholerae; Mobile genetic elements. 2012. DOI : 10.4161/mge.22284.
J. M. Chen; S. Uplekar; S. V. Gordon; S. T. Cole : A Point Mutation in cycA Partially Contributes to the D-cycloserine Resistance Trait of Mycobacterium bovis BCG Vaccine Strains; Plos One. 2012. DOI : 10.1371/journal.pone.0043467.
M. Chiriaco; G. Farinelli; V. Capo; G. Di Matteo; S. Di Cesare et al. : Regulated Lentiviral Vector Gene Transfer For X-Cgd. 2012. 15th Biennial Meeting European-Society-for-Immunodeficiency (ESID), Florence, ITALY, OCT 03-06, 2012. p. 126-127.
B. Lemaitre : The drosophila gut: A new paradigm for epithelial immune response. 2012. 10th Joint Meeting of the International-Cytokine-Society (ICS) / Meeting of the International-Society-for-Interferon-and-Cytokine-Research (ISICR), Geneva, SWITZERLAND, SEP 11-14, 2012. p. 494-494. DOI : 10.1016/j.cyto.2012.06.305.
C. Neyen; B. Lemaitre : Distinguishing dead from alive - a novel intracellular receptor mediates ligand-specific regulation of Relish-dependent immune activation in Drosophila. 2012. European Congress of Immunology, Glasgow, SCOTLAND, SEP 05-08, 2012. p. 32-32.
J. Neres; F. Pojer; E. Molteni; L. R. Chiarelli; N. Dhar et al. : Structural Basis for Benzothiazinone-Mediated Killing of Mycobacterium tuberculosis; Science Translational Medicine. 2012. DOI : 10.1126/scitranslmed.3004395.
M. Bischofberger; I. Iacovache; G. van der Goot : Pathogenic Pore-Forming Proteins: Function and Host Response; Cell Host & Microbe. 2012. DOI : 10.1016/j.chom.2012.08.005.
R. C. Hartkoorn; C. Sala; J. Neres; F. Pojer; S. Magnet et al. : Towards a new tuberculosis drug: pyridomycin - nature's isoniazid; Embo Molecular Medicine. 2012. DOI : 10.1002/emmm.201201689.
R. Bernasconi; J. Noack; M. Molinari : Unconventional roles of nonlipidated LC3 in ERAD tuning and coronavirus infection; Autophagy. 2012. DOI : 10.4161/auto.21229.
D. N. Hebert; M. Molinari : Flagging and docking: dual roles for N-glycans in protein quality control and cellular proteostasis; Trends In Biochemical Sciences. 2012. DOI : 10.1016/j.tibs.2012.07.005.
V. Capo; G. Farinelli; B. Gentner; G. Di Matteo; S. Di Cesare et al. : Regulated lentiviral vector gene transfer for X-CGD. 2012. Collaborative Congress of the European-Society-of-Gene-and-Cell-Therapy/French-Society-of-Cell-and-Gene-Therapy, Versailles, FRANCE, OCT 25-29, 2012. p. A52-A52.
Z. Veneti; S. Zabalou; G. Papafotiou; C. Paraskevopoulos; S. Pattas et al. : Loss of reproductive parasitism following transfer of male-killing Wolbachia to Drosophila melanogaster and Drosophila simulans; Heredity. 2012. DOI : 10.1038/hdy.2012.43.
B. Lechartier; R. C. Hartkoorn; S. T. Cole : In Vitro Combination Studies of Benzothiazinone Lead Compound BTZ043 against Mycobacterium tuberculosis; Antimicrobial Agents And Chemotherapy. 2012. DOI : 10.1128/Aac.01476-12.
M. Zhang; C. Sala; R. C. Hartkoorn; N. Dhar; A. Mendoza-Losana et al. : Streptomycin-Starved Mycobacterium tuberculosis 18b, a Drug Discovery Tool for Latent Tuberculosis; Antimicrobial Agents And Chemotherapy. 2012. DOI : 10.1128/Aac.01125-12.
B. D. Robertson; D. Altmann; C. Barry; B. Bishai; S. Cole et al. : Detection and treatment of subclinical tuberculosis; Tuberculosis. 2012. DOI : 10.1016/
M. Elitas : Single-Cell Analysis of Mycobacterial Persistence Using Microfabricated Tools. Lausanne, EPFL, 2012. DOI : 10.5075/epfl-thesis-5621.
S. Uplekar : Genomics and transcriptomics of the Mycobacterium tuberculosis complex. Lausanne, EPFL, 2012. DOI : 10.5075/epfl-thesis-5550.
M. Blokesch : TransFLP - A Method to Genetically Modify Vibrio cholerae Based on Natural Transformation and FLP-recombination; Journal of Visualized Experiments : JoVE. 2012. DOI : 10.3791/3761.
N. A. Broderick; B. Lemaitre : Gut-associated microbes of Drosophila melanogaster; Gut microbes. 2012. DOI : 10.4161/gmic.19896.
J. Herren; B. Lemaitre : Insect-microbe interactions: the good, the bad and the others; Current opinion in microbiology. 2012. DOI : 10.1016/j.mib.2012.05.014.
C. Neyen; M. Poidevin; A. Roussel; B. Lemaitre : Tissue- and ligand-specific sensing of gram-negative infection in drosophila by PGRP-LC isoforms and PGRP-LE; Journal of immunology (Baltimore, Md. : 1950). 2012. DOI : 10.4049/jimmunol.1201022.
S. Chakrabarti; P. Liehl; N. Buchon; B. Lemaitre : Infection-induced host translational blockage inhibits immune responses and epithelial renewal in the Drosophila gut; Cell host & microbe. 2012. DOI : 10.1016/j.chom.2012.06.001.
D. Osman; N. Buchon; S. Chakrabarti; Y.-T. Huang; W.-C. Su et al. : Autocrine and paracrine unpaired signalling regulate intestinal stem cell maintenance and division; Journal of cell science. 2012. DOI : 10.1242/jcs.113100.
P. J. Clark; A. J. Thompson; M. Zhu; D. M. Vock; Q. Zhu et al. : Interleukin 28B polymorphisms are the only common genetic variants associated with low-density lipoprotein cholesterol (LDL-C) in genotype-1 chronic hepatitis C and determine the association between LDL-C and treatment response; Journal of viral hepatitis. 2012. DOI : 10.1111/j.1365-2893.2011.01553.x.
P. J. Clark; A. J. Thompson; Q. Zhu; D. M. Vock; M. Zhu et al. : The association of genetic variants with hepatic steatosis in patients with genotype 1 chronic hepatitis C infection; Digestive diseases and sciences. 2012. DOI : 10.1007/s10620-012-2171-y.
S. Quenneville; P. Turelli; K. Bojkowska; C. Raclot; S. Offner et al. : The KRAB-ZFP/KAP1 System Contributes to the Early Embryonic Establishment of Site-Specific DNA Methylation Patterns Maintained during Development; Cell Reports. 2012. DOI : 10.1016/j.celrep.2012.08.043.
T. Herbst; J. Esser; M. Prati; M. Kulagin; R. Stettler et al. : Antibodies and IL-3 support helminth-induced basophil expansion; Proc Natl Acad Sci USA. 2012. DOI : 10.1073/pnas.1117584109.
A. Corsinotti : KRAB/KAP1 Regulation of Embryonic Stem Cell Pluripotent Self-renewal. Lausanne, EPFL, 2012. DOI : 10.5075/epfl-thesis-5436.
S. de Sio; R. Francesca; I. Barde; S. Offner; A. Kapopoulou et al. : KAP1 regulates gene networks controlling T-cell development and responsiveness; FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2012. DOI : 10.1096/fj.12-206177.
R. Bernasconi; C. Galli; J. Noack; S. Bianchi; C. A. M. de Haan et al. : Role of the SEL1L:LC3-I Complex as an ERAD Tuning Receptor in the Mammalian ER; Molecular Cell. 2012. DOI : 10.1016/j.molcel.2012.04.017.
L. Vera-Cabrera; M. P. Campos-Rivera; N. A. Gonzalez-Martinez; J. Ocampo-Candiani; S. T. Cole : In Vitro Activities of the New Antitubercular Agents PA-824 and BTZ043 against Nocardia brasiliensis; Antimicrobial Agents And Chemotherapy. 2012. DOI : 10.1128/AAC.00115-12.
E. Gelman; J. D. McKinney; N. Dhar : Malachite Green Interferes with Postantibiotic Recovery of Mycobacteria; Antimicrobial Agents And Chemotherapy. 2012. DOI : 10.1128/AAC.00406-12.
J. M. Rojek; M.-L. Moraz; C. Pythoud; S. Rothenberger; G. van der Goot et al. : Binding of Lassa virus perturbs extracellular matrix-induced signal transduction via dystroglycan; Cellular Microbiology. 2012. DOI : 10.1111/j.1462-5822.2012.01784.x.
M. Akerblom; R. Sachdeva; I. Barde; S. Verp; B. Gentner et al. : MicroRNA-124 Is a Subventricular Zone Neuronal Fate Determinant; The Journal of neuroscience : the official journal of the Society for Neuroscience. 2012. DOI : 10.1523/JNEUROSCI.0558-12.2012.
T. S. Macfarlan; W. D. Gifford; S. Driscoll; K. Lettieri; H. M. Rowe et al. : Embryonic stem cell potency fluctuates with endogenous retrovirus activity; Nature. 2012. DOI : 10.1038/nature11244.
M. Lo Scrudato; M. Blokesch : The Regulatory Network of Natural Competence and Transformation of Vibrio cholerae; PLoS Genetics. 2012. DOI : 10.1371/journal.pgen.1002778.
G. Imre; J. Heering; A.-N. Takeda; M. Husmann; B. Thiede et al. : Caspase-2 is an initiator caspase responsible for pore-forming toxin-mediated apoptosis; Embo Journal. 2012. DOI : 10.1038/emboj.2012.93.
J. Kzhyshkowska; C. Neyen; S. Gordon : Role of macrophage scavenger receptors in atherosclerosis; Immunobiology. 2012. DOI : 10.1016/j.imbio.2012.02.015.
K. Bojkowska; F. Aloisio; M. Cassano; A. Kapopoulou; F. Santoni De Sio et al. : Liver-specific ablation of Krüppel-associated box-associated protein 1 in mice leads to male-predominant hepatosteatosis and development of liver adenoma; Hepatology. 2012. DOI : 10.1002/hep.25767.
M. Raviglione; B. Marais; K. Floyd; K. Loennroth; H. Getahun et al. : Scaling up interventions to achieve global tuberculosis control: progress and new developments; Lancet. 2012.
M. Mulet; M. Gomila; B. Lemaitre; J. Lalucat; E. Garcia-Valdes : Taxonomic characterisation of Pseudomonas strain L48 and formal proposal of Pseudomonas entomophila sp nov.; Systematic And Applied Microbiology. 2012. DOI : 10.1016/j.syapm.2011.12.003.
A. C. Groner; P. Tschopp; L. Challet; J.-E. Dietrich; S. Verp et al. : The Kruppel-associated Box Repressor Domain Can Induce Reversible Heterochromatization of a Mouse Locus in Vivo; The Journal of biological chemistry. 2012. DOI : 10.1074/jbc.M112.350884.
A. Rinaldo; E. Bertuzzo; L. Mari; L. Righetto; M. Blokesch et al. : Reassessment of the 2010-2011 Haiti cholera outbreak and rainfall-driven multiseason projections; Proceedings of the National Academy of Sciences. 2012. DOI : 10.1073/pnas.1203333109.
B. Blasco; J. M. Chen; R. Hartkoorn; C. Sala; S. Uplekar et al. : Virulence Regulator EspR of Mycobacterium tuberculosis Is a Nucleoid-Associated Protein; Plos Pathogens. 2012. DOI : 10.1371/journal.ppat.1002621.
D. Trono : Gene therapy: too much splice can spoil the dish; The Journal of clinical investigation. 2012. DOI : 10.1172/JCI63066.
R. C. Hartkoorn; C. Sala; S. Uplekar; P. Busso; J. Rougemont et al. : Genome-Wide Definition of the SigF Regulon in Mycobacterium tuberculosis; Journal Of Bacteriology. 2012. DOI : 10.1128/JB.06692-11.
S. T. Cole : INFECTIOUS DISEASES Transporter targeted in tuberculosis; Nature Chemical Biology. 2012. DOI : 10.1038/nchembio.918.
J. E. Griffin; A. K. Pandey; S. A. Gilmore; V. Mizrahi; J. D. Mckinney et al. : Cholesterol Catabolism by Mycobacterium tuberculosis Requires Transcriptional and Metabolic Adaptations; Chemistry & Biology. 2012. DOI : 10.1016/j.chembiol.2011.12.016.
S. de Sio; R. Francesca; J. Massacand; I. Barde; S. Offner et al. : KAP1 regulates gene networks controlling mouse B-lymphoid cell differentiation and function; Blood. 2012. DOI : 10.1182/blood-2011-12-401117.
B. Mollwitz; E. Brunk; S. Schmitt; F. Pojer; M. Bannwarth et al. : Directed evolution of the suicide protein O⁶-alkylguanine-DNA alkyltransferase for increased reactivity results in an alkylated protein with exceptional stability; Biochemistry. 2012. DOI : 10.1021/bi2016537.
J. Deuquet; E. Lausch; A. Superti-Furga; G. van der Goot : The dark sides of capillary morphogenesis gene 2; The EMBO journal. 2012. DOI : 10.1038/emboj.2011.442.
E. Fullam; F. Pojer; T. Bergfors; T. A. Jones; S. T. Cole : Structure and function of the transketolase from Mycobacterium tuberculosis and comparison with the human enzyme; Open Biology. 2012. DOI : 10.1098/rsob.110026.
D. White; I. U. Rafalska-Metcalf; A. V. Ivanov; A. Corsinotti; H. Peng et al. : The ATM substrate KAP1 controls DNA repair in heterochromatin: Regulation by HP1 proteins and Serine 473/824 phosphorylation; Molecular cancer research : MCR. 2012. DOI : 10.1158/1541-7786.MCR-11-0134.
C. Trefzer; H. Škovierová; S. Buroni; A. Bobovská; S. Nenci et al. : Benzothiazinones Are Suicide Inhibitors of Mycobacterial Decaprenylphosphoryl-β-; Journal of the American Chemical Society. 2012. DOI : 10.1021/ja211042r.
M. Blokesch : Chitin colonization, chitin degradation and chitin-induced natural competence of Vibrio cholerae are subject to catabolite repression; Environmental Microbiology. 2012. DOI : 10.1111/j.1462-2920.2011.02689.x.


A. Persat; J. G. Santiago : MicroRNA profiling by simultaneous selective isotachophoresis and hybridization with molecular beacons; Analytical chemistry. 2011. DOI : 10.1021/ac103225c.
M. Salathé; S. Khandelwal : Assessing vaccination sentiments with online social media: implications for infectious disease dynamics and control; PLoS computational biology. 2011. DOI : 10.1371/journal.pcbi.1002199.
J. Jones; M. Salathé; M. Feldman; M. Kazandjieva; J. Lee et al. : Measuring school contact networks using wireless sensor technology. 2011. 36th Annual Meeting: Human Biology Association, Minneapolis, Minesota, USA, April 13-14, 2011. p. 263. DOI : 10.1002/ajhb.21153.
F. Bauernfeind; A. Ablasser; E. Bartok; S. Kim; J. Schmid-Burgk et al. : Inflammasomes: current understanding and open questions; Cellular and molecular life sciences : CMLS. 2011. DOI : 10.1007/s00018-010-0567-4.
A. Ablasser; V. Hornung : Where, in antiviral defense, does IFIT1 fit?; Nature immunology. 2011. DOI : 10.1038/ni.2061.
M. Lemos; J. McKinney; K. Rhee : Dispensability of Surfactant Proteins A and D in Immune Control of Mycobacterium tuberculosis Infection following Aerosol Challenge of Mice; INFECTION AND IMMUNITY. 2011.
K. Pelak; A. C. Need; J. Fellay; K. V. Shianna; S. Feng et al. : Copy Number Variation of KIR Genes Influences HIV-1 Control; Plos Biology. 2011. DOI : 10.1371/journal.pbio.1001208.
J. Snoeck; J. Fellay; I. Bartha; D. C. Douek; A. Telenti : Mapping of positive selection sites in the HIV-1 genome in the context of RNA and protein structural constraints; Retrovirology. 2011. DOI : 10.1186/1742-4690-8-87.
T. Herbst : Modulation of immune responses by commensal bacteria and intestinal helminth. ETH Zürich, 2011. DOI : 10.3929/ethz-a-007084676.
K. Rajalingam; G. van der Goot : When cells and microbes meet in Krakow; EMBO reports. 2011. DOI : 10.1038/embor.2011.27.
P. Szczesny; I. Iacovache; A. Muszewska; K. Ginalski; G. van der Goot et al. : Extending the aerolysin family: from bacteria to vertebrates; PloS one. 2011. DOI : 10.1371/journal.pone.0020349.
C. Frecha; C. Costa; D. Nègre; F. Amirache; D. Trono et al. : A novel lentiviral vector targets gene transfer into human hematopoietic stem cells in marrow from patients with bone marrow failure syndrome and in vivo in humanized mice; Blood. 2011. DOI : 10.1182/blood-2011-04-346619.
C. Sala; R. C. Hartkoorn : Tuberculosis drugs: new candidates and how to find more; Future microbiology. 2011. DOI : 10.2217/fmb.11.46.
J. M. Chen; S. Boy-Röttger; N. Dhar; N. Sweeney; R. S. Buxton et al. : EspD Is Critical for the Virulence-Mediating ESX-1 Secretion System in Mycobacterium tuberculosis; Journal of bacteriology. 2011. DOI : 10.1128/JB.06417-11.
T. B. Feyerabend; A. Weiser; A. Tietz; M. Stassen; N. Harris et al. : Cre-mediated cell ablation contests mast cell contribution in models of antibody- and T cell-mediated autoimmunity; Immunity. 2011. DOI : 10.1016/j.immuni.2011.09.015.
I. Thiele; D. R. Hyduke; B. Steeb; G. Fankam; D. K. Allen et al. : A community effort towards a knowledge-base and mathematical model of the human pathogen Salmonella Typhimurium LT2; Bmc Systems Biology. 2011. DOI : 10.1186/1752-0509-5-8.
C. Galli; R. Bernasconi; T. Solda; V. Calanca; M. Molinari : Malectin Participates in a Backup Glycoprotein Quality Control Pathway in the Mammalian ER; Plos One. 2011. DOI : 10.1371/journal.pone.0016304.
I. Mosconi; J. C. Massacand; L. Harris : Role of thymic stromal lymphopoietin (TSLP) signaling in intestinal immune homeostasis. 2011. p. 104-105.
E. Bertuzzo; L. Mari; L. Righetto; M. Gatto; R. Casagrandi et al. : Prediction of the spatial evolution and effects of control measures for the unfolding Haiti cholera outbreak; Geophysical Research Letters. 2011. DOI : 10.1029/2011GL046823.
M. Pastoriza-Gallego; L. Rabah; G. Gibrat; B. Thiebot; G. van der Goot et al. : Dynamics of Unfolded Protein Transport through an Aerolysin Pore; Journal Of The American Chemical Society. 2011. DOI : 10.1021/ja1073245.
M. Zhang; S.-Y. Li; I. M. Rosenthal; D. V. Almeida; Z. Ahmad et al. : Treatment of Tuberculosis with Rifamycin-containing Regimens in Immune-deficient Mice; American Journal Of Respiratory And Critical Care Medicine. 2011. DOI : 10.1164/rccm.201012-1949OC.
J. Deuquet; E. Lausch; N. Guex; L. Abrami; S. Salvi et al. : Hyaline Fibromatosis Syndrome inducing mutations in the ectodomain of anthrax toxin receptor 2 can be rescued by proteasome inhibitors; Embo Molecular Medicine. 2011. DOI : 10.1002/emmm.201100124.
R. Bernasconi; M. Molinari : ERAD and ERAD tuning: disposal of cargo and of ERAD regulators from the mammalian ER; Current Opinion In Cell Biology. 2011. DOI : 10.1016/
S. Cole : New medicines for tuberculosis: benzothiazinones. 2011. 36th FEBS Congress of the Biochemistry for Tomorrows Medicine, Torino, ITALY, Jun 25-30, 2011. p. 61-61.
A. Fairlamb; S. Cole : Antimicrobial drug discovery; Future Microbiology. 2011. DOI : 10.2217/FMB.11.54.
M. R. Gonzalez; M. Bischofberger; B. Freche; S. Ho; R. G. Parton et al. : Pore-forming toxins induce multiple cellular responses promoting survival; Cellular Microbiology. 2011. DOI : 10.1111/j.1462-5822.2011.01600.x.
F. Reggiori; C. A. M. de Haan; M. Molinari : Unconventional Use of LC3 by Coronaviruses through the Alleged Subversion of the ERAD Tuning Pathway; Viruses-Basel. 2011. DOI : 10.3390/v3091610.
G. J. Vanasse; J.-Y. Jeong; J. Tate; H. Bathulapalli; D. Anderson et al. : A polymorphism in the leptin gene promoter is associated with anemia in patients with HIV disease; Blood. 2011. DOI : 10.1182/blood-2011-06-362194.
A. Zaidman-Rémy; M. Poidevin; M. Hervé; D. P. Welchman; J. C. Paredes et al. : Drosophila immunity: analysis of PGRP-SB1 expression, enzymatic activity and function; PloS one. 2011. DOI : 10.1371/journal.pone.0017231.
J. C. Paredes; D. P. Welchman; M. Poidevin; B. Lemaitre : Negative Regulation by Amidase PGRPs Shapes the Drosophila Antibacterial Response and Protects the Fly from Innocuous Infection; Immunity. 2011. DOI : 10.1016/j.immuni.2011.09.018.
T. Kuraishi; O. Binggeli; O. Opota; N. Buchon; B. Lemaitre : Genetic evidence for a protective role of the peritrophic matrix against intestinal bacterial infection in Drosophila melanogaster; Proceedings of the National Academy of Sciences of the United States of America. 2011. DOI : 10.1073/pnas.1105994108.
L. Vera-Cabrera; W. G. Escalante-Fuentes; M. Gomez-Flores; J. Ocampo-Candiani; P. Busso et al. : A Case of Diffuse Lepromatous Leprosy associated with Mycobacterium lepromatosis; Journal of clinical microbiology. 2011. DOI : 10.1128/JCM.05634-11.
S. T. Cole : Microbiology. Pyrazinamide--old TB drug finds new target; Science (New York, N.Y.). 2011. DOI : 10.1126/science.1212450.
S. T. Cole; G. Riccardi : New tuberculosis drugs on the horizon; Current opinion in microbiology. 2011. DOI : 10.1016/j.mib.2011.07.022.
S. Uplekar; B. Heym; V. Friocourt; J. Rougemont; S. T. Cole : Comparative genomics of Esx genes from clinical isolates of Mycobacterium tuberculosis provides evidence for gene conversion and epitope variation; Infection and immunity. 2011. DOI : 10.1128/IAI.05344-11.
R. W. Truman; P. Singh; R. Sharma; P. Busso; J. Rougemont et al. : Probable zoonotic leprosy in the southern United States; The New England journal of medicine. 2011. DOI : 10.1056/NEJMoa1010536.
P. Singh; P. Busso; A. Paniz-Mondolfi; N. Aranzazu; M. Monot et al. : Molecular drug susceptibility testing and genotyping of Mycobacterium leprae strains from South America; Antimicrobial agents and chemotherapy. 2011. DOI : 10.1128/AAC.00201-11.
D. Bottai; L. Majlessi; R. Simeone; W. Frigui; C. Laurent et al. : ESAT-6 secretion-independent impact of ESX-1 genes espF and espG1 on virulence of Mycobacterium tuberculosis; The Journal of infectious diseases. 2011. DOI : 10.1093/infdis/jiq089.
M. P. Lemos; K. Y. Rhee; J. D. McKinney : Expression of the leptin receptor outside of bone marrow-derived cells regulates tuberculosis control and lung macrophage MHC expression; Journal of immunology (Baltimore, Md. : 1950). 2011. DOI : 10.4049/jimmunol.1003226.
M. A. Kirksey; A. D. Tischler; R. Siméone; K. B. Hisert; S. Uplekar et al. : Spontaneous phthiocerol dimycocerosate-deficient variants of Mycobacterium tuberculosis are susceptible to gamma interferon-mediated immunity; Infection and immunity. 2011. DOI : 10.1128/IAI.00097-11.
J. K. Herren; B. Lemaitre : Spiroplasma and host immunity: activation of humoral immune responses increases endosymbiont load and susceptibility to certain Gram-negative bacterial pathogens in Drosophila melanogaster; Cellular microbiology. 2011. DOI : 10.1111/j.1462-5822.2011.01627.x.
O. Opota; I. Vallet-Gély; R. Vincentelli; C. Kellenberger; I. Iacovache et al. : Monalysin, a novel ß-pore-forming toxin from the Drosophila pathogen Pseudomonas entomophila, contributes to host intestinal damage and lethality; PLoS pathogens. 2011. DOI : 10.1371/journal.ppat.1002259.
S. Quenneville; G. Verde; A. Corsinotti; A. Kapopoulou; J. Jakobsson et al. : In Embryonic Stem Cells, ZFP57/KAP1 Recognize a Methylated Hexanucleotide to Affect Chromatin and DNA Methylation of Imprinting Control Regions; Molecular Cell. 2011. DOI : 10.1016/j.molcel.2011.08.032.
A. Rinaldo; M. Blokesch; E. Bertuzzo; L. Mari; L. Righetto et al. : A transmission model of the 2010 cholera epidemic in haiti; Annals of internal medicine. 2011. DOI : 10.1059/0003-4819-155-6-201109200-00018.
R. Duvoisin; M. A. Ayuk; G. Rinaldi; S. Suttiprapa; V. H. Mann et al. : Human U6 promoter drives stronger shRNA activity than its schistosome orthologue in Schistosoma mansoni and human fibrosarcoma cells; Transgenic research. 2011. DOI : 10.1007/s11248-011-9548-0.
B. Blasco; M. Stenta; L. Alonso-Sarduy; G. Dietler; M. Dal Peraro et al. : Atypical DNA recognition mechanism used by the EspR virulence regulator of Mycobacterium tuberculosis; Molecular Microbiology. 2011. DOI : 10.1111/j.1365-2958.2011.07813.x.
G. Suckow; P. Seitz; M. Blokesch : Quorum Sensing Contributes to Natural Transformation of Vibrio cholerae in a Species-Specific Manner; Journal of Bacteriology. 2011. DOI : 10.1128/JB.05396-11.
M. Ballester; C. Nembrini; N. Dhar; A. de Titta; C. de Piano et al. : Nanoparticle conjugation and pulmonary delivery enhance the protective efficacy of Ag85B and CpG against tuberculosis; Vaccine. 2011. DOI : 10.1016/j.vaccine.2011.07.039.
I. Iacovache; M. T. Degiacomi; L. Pernot; S. Ho; M. Schiltz et al. : Dual Chaperone Role of the C-Terminal Propeptide in Folding and Oligomerization of the Pore-Forming Toxin Aerolysin; PLoS Pathogens. 2011. DOI : 10.1371/journal.ppat.1002135.
S. Meylan; A. C. Groner; G. Ambrosini; N. Malani; S. Quenneville et al. : A gene-rich, transcriptionally active environment and the pre-deposition of repressive marks are predictive of susceptibility to KRAB/KAP1-mediated silencing; BMC genomics. 2011. DOI : 10.1186/1471-2164-12-378.
K. Bojkowska; F. Santoni De Sio; I. Barde; S. Offner; S. Verp et al. : Measuring In Vivo Protein Half-Life; Chemistry & Biology. 2011. DOI : 10.1016/j.chembiol.2011.03.014.
K. Bojkowska : In Vivo Studies on the Control of Gene Expression and Protein Degradation. Lausanne, EPFL, 2011. DOI : 10.5075/epfl-thesis-5119.
M. Rotger; J. Dalmau; A. Rauch; P. McLaren; S. Bosinger et al. : Comparative transcriptomics of extreme phenotypes of human HIV-1 infection and SIV infection in sooty mangabey and rhesus macaque; The Journal of clinical investigation. 2011. DOI : 10.1172/JCI45235.
N. Harris; W. C. Gause : To B or not to B: B cells and the Th2-type immune response to helminths; Trends in immunology. 2011. DOI : 10.1016/
N. L. Harris : Advances in helminth immunology: optimism for future vaccine design?; Trends in parasitology. 2011. DOI : 10.1016/
T. Herbst; A. Sichelstiel; C. Schär; K. Yadava; K. Bürki et al. : Dysregulation of Allergic Airway Inflammation in the Absence of Microbial Colonization; American journal of respiratory and critical care medicine. 2011. DOI : 10.1164/rccm.201010-1574OC.
C. Schaer; S. Hiltbrunner; B. Ernst; C. Mueller; M. Kurrer et al. : HVEM Signalling Promotes Colitis; PloS one. 2011. DOI : 10.1371/journal.pone.0018495.
I. Barde; S. Verp; S. E. Offner; D. Trono : Lentiviral Vector Mediated Transgenesis; Current Protocols in Mouse Biology 1. 2011. DOI : 10.1002/9780470942390.mo100169.
I. Barde; E. Laurenti; S. Verp; M. Wiznerowicz; S. Offner et al. : Lineage- and stage-restricted lentiviral vectors for the gene therapy of chronic granulomatous disease; Gene therapy. 2011. DOI : 10.1038/gt.2011.65.
A. Rauch; J. Fellay : Personalized hepatitis C therapy: opportunities and pitfalls; Expert review of molecular diagnostics. 2011. DOI : 10.1586/erm.10.116.
Y. Hitomi; E. T. Cirulli; J. Fellay; J. G. McHutchison; A. J. Thompson et al. : Inosine triphosphate protects against ribavirin-induced adenosine triphosphate loss by adenylosuccinate synthase function; Gastroenterology. 2011. DOI : 10.1053/j.gastro.2010.12.038.
S. Petrovski; J. Fellay; K. V. Shianna; N. Carpenetti; J. Kumwenda et al. : Common human genetic variants and HIV-1 susceptibility: a genome-wide survey in a homogeneous African population; AIDS. 2011. DOI : 10.1097/QAD.0b013e328343817b.
N. H. Afdhal; J. G. McHutchison; S. Zeuzem; A. Mangia; J.-M. Pawlotsky et al. : Hepatitis C pharmacogenetics: state of the art in 2010; Hepatology. 2011. DOI : 10.1002/hep.24052.
S. M. Bol; P. D. Moerland; S. Limou; Y. van Remmerden; C. Coulonges et al. : Genome-wide association study identifies single nucleotide polymorphism in DYRK1A associated with replication of HIV-1 in monocyte-derived macrophages; PloS one. 2011. DOI : 10.1371/journal.pone.0017190.
J. Fellay; N. Frahm; K. V. Shianna; E. T. Cirulli; D. R. Casimiro et al. : Host genetic determinants of T cell responses to the MRKAd5 HIV-1 gag/pol/nef vaccine in the step trial; The Journal of infectious diseases. 2011. DOI : 10.1093/infdis/jiq125.
J. di Iulio; A. Ciuffi; K. Fitzmaurice; D. Kelleher; M. Rotger et al. : Estimating the net contribution of IL28B variation to spontaneous hepatitis C virus clearance; Hepatology. 2011. DOI : 10.1002/hep.24263.
E. Evangelou; J. Fellay; S. Colombo; J. Martinez-Picado; N. Obel et al. : Impact of Phenotype Definition on Genome-Wide Association Signals: Empirical Evaluation in Human Immunodeficiency Virus Type 1 Infection; American Journal of Epidemiology. 2011. DOI : 10.1093/aje/kwr024.
J.-R. Alattia; T. Kuraishi; M. Dimitrov; I. Chang; B. Lemaitre et al. : Mercury is a direct and potent γ-secretase inhibitor affecting Notch processing and development in Drosophila; The FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2011. DOI : 10.1096/fj.10-174078.
D. Robyr; M. Friedli; C. Gehrig; M. Arcangeli; M. Marin et al. : Chromosome Conformation Capture Uncovers Potential Genome-Wide Interactions between Human Conserved Non-Coding Sequences; PloS one. 2011. DOI : 10.1371/journal.pone.0017634.
D. Trono; F. Marzetta : Profaning the Ultimate Sanctuary: HIV Latency in Hematopoietic Stem Cells; Cell host & microbe. 2011. DOI : 10.1016/j.chom.2011.03.001.
C. E. Pasi; A. Dereli-Öz; S. Negrini; M. Friedli; G. Fragola et al. : Genomic instability in induced stem cells; Cell death and differentiation. 2011. DOI : 10.1038/cdd.2011.9.
H. M. Rowe; D. Trono : Dynamic control of endogenous retroviruses during development; Virology. 2011. DOI : 10.1016/j.virol.2010.12.007.
A. C. Groner : Studies on KRAB/KAP1-Mediated Transcriptional Repression. Lausanne, EPFL, 2011. DOI : 10.5075/epfl-thesis-4972.
R. M. Gonzalez : Cellular Responses to Bacterial Pore-Forming Toxins. Lausanne, EPFL, 2011. DOI : 10.5075/epfl-thesis-4965.
M. I. Iacovache : Folding and Structure of the Pore Forming Toxin Aerolysin. Lausanne, EPFL, 2011. DOI : 10.5075/epfl-thesis-4925.
J. Deuquet Ariosa : Molecular Mechanisms Underlying Hyaline Fibromatosis Syndrome. Lausanne, EPFL, 2011. DOI : 10.5075/epfl-thesis-4909.
A. D. Tischler; J. D. McKinney : Bacterial strategies for survival in the host; The immune response to infection; Washington, D.C: ASM Press, 2011. p. 425-440.


A. Persat; R. R. Chivukula; J. T. Mendell; J. G. Santiago : Quantification of global microRNA abundance by selective isotachophoresis; Analytical chemistry. 2010. DOI : 10.1021/ac102496m.
S. Funk; M. Salathé; V. A. A. Jansen : Modelling the influence of human behaviour on the spread of infectious diseases: a review; Journal of the Royal Society, Interface / the Royal Society. 2010. DOI : 10.1098/rsif.2010.0142.
M. Salathé; M. Kazandjieva; J. W. Lee; P. Levis; M. W. Feldman et al. : A high-resolution human contact network for infectious disease transmission; Proceedings of the National Academy of Sciences of the United States of America. 2010. DOI : 10.1073/pnas.1009094108.
M. Salathé; J. H. Jones : Dynamics and control of diseases in networks with community structure; PLoS computational biology. 2010. DOI : 10.1371/journal.pcbi.1000736.
D. J. Salkeld; M. Salathé; P. Stapp; J. H. Jones : Plague outbreaks in prairie dog populations explained by percolation thresholds of alternate host abundance; Proceedings of the National Academy of Sciences of the United States of America. 2010. DOI : 10.1073/pnas.1002826107.
M. Kazandjieva; J. Lee; M. Salathé; M. Feldman; J. Jones et al. : Experiences in measuring a human contact network for epidemiology research. 2010. 6th Workshop on Hot Topics in Embedded Networked Sensors (HotEMNETS'10), Killarney, Ireland, June 28-29, 2010. p. 7. DOI : 10.1145/1978642.1978651.
R. Mostowy; M. Salathé; R. D. Kouyos; S. Bonhoeffer : On the evolution of sexual reproduction in hosts coevolving with multiple parasites; Evolution; international journal of organic evolution. 2010. DOI : 10.1111/j.1558-5646.2010.00951.x.
S. Kim; F. Bauernfeind; A. Ablasser; G. Hartmann; K. A. Fitzgerald et al. : Listeria monocytogenes is sensed by the NLRP3 and AIM2 inflammasome; European journal of immunology. 2010. DOI : 10.1002/eji.201040425.
F. Bauernfeind; A. Ablasser; S. Kim; E. Bartok; V. Hornung : An unexpected role for RNA in the recognition of DNA by the innate immune system; RNA biology. 2010.
R. Bernasconi; C. Galli; V. Calanca; T. Nakajima; M. Molinari : Stringent requirement for HRD1, SEL1L, and OS-9/XTP3-B for disposal of ERAD-L-S substrates; Journal Of Cell Biology. 2010. DOI : 10.1083/jcb.200910042.
M. Aebi; R. Bernasconi; S. Clerc; M. Molinari : N-glycan structures: recognition and processing in the ER; Trends In Biochemical Sciences. 2010. DOI : 10.1016/j.tibs.2009.10.001.
D. N. Hebert; R. Bernasconi; M. Molinari : ERAD substrates: Which way out?; Seminars In Cell & Developmental Biology. 2010. DOI : 10.1016/j.semcdb.2009.12.007.
F. Reggiori; I. Monastyrska; M. H. Verheije; T. Cali; M. Ulasli et al. : Coronaviruses Hijack the LC3-I-Positive EDEMosomes, ER-Derived Vesicles Exporting Short-Lived ERAD Regulators, for Replication; Cell Host & Microbe. 2010. DOI : 10.1016/j.chom.2010.05.013.
G. Manina; M. R. Pasca; S. Buroni; E. De Rossi; G. Riccardi : Decaprenylphosphoryl-beta-D-Ribose 2 '-Epimerase from Mycobacterium tuberculosis is a Magic Drug Target; Current Medicinal Chemistry. 2010.
M. Degiacomi; I. Iacovache; G. van der Goot; M. Dal Peraro : A model for the assembly and activation process of the pore-forming toxin Aerolysin. 2010. 35th Congress of the Federation-of-European-Biochemical-Societies, Gothenburg, SWEDEN, Jun 26-Jul 01, 2010. p. 194-194.
P. Domenech; G. S. Kolly; L. Leon-Solis; A. Fallow; M. B. Reed : Massive Gene Duplication Event among Clinical Isolates of the Mycobacterium tuberculosis W/Beijing Family; Journal Of Bacteriology. 2010. DOI : 10.1128/JB.00536-10.
R. Bernasconi; T. Solda; C. Galli; T. Pertel; J. Luban et al. : Cyclosporine A-Sensitive, Cyclophilin B-Dependent Endoplasmic Reticulum-Associated Degradation; Plos One. 2010. DOI : 10.1371/journal.pone.0013008.
L. Pernot; M. Schiltz; G. van der Goot : Preliminary crystallographic analysis of two oligomerization-deficient mutants of the aerolysin toxin, H132D and H132N, in their proteolyzed forms; Acta Crystallographica Section F-Structural Biology And Crystallization Communications. 2010. DOI : 10.1107/S1744309110041035.
C. Neyen; M. Poidevin; Q. Geissmann; B. Lemaitre : Cell biology of Drosophila peptidoglycan recognition: receptor trafficking and negative feedback regulation cooperate to fine-tune imd (NFkB) pathway activation. 2010. Annual Congress of the British-Society-for-Immunology, Liverpool, ENGLAND, Dec 06-10, 2010. p. 85-85.
B. Lemaitre : Toll-like receptors - an evolutionary perspective. 2010. Annual Congress of the British-Society-for-Immunology, Liverpool, ENGLAND, Dec 06-10, 2010. p. 19-19.
C. A. M. de Haan; M. Molinari; F. Reggiori : Autophagy-independent LC3 function in vesicular traffic; Autophagy. 2010. DOI : 10.4161/auto.6.7.13309.
N. Berthet; A. Deletoile; V. Passet; G. C. Kennedy; J.-C. Manuguerra et al. : Reconstructed ancestral sequences improve pathogen identification using resequencing DNA microarrays; PloS one. 2010. DOI : 10.1371/journal.pone.0015243.
P. Singh; S. T. Cole : Mycobacterium leprae: genes, pseudogenes and genetic diversity; Future microbiology. 2010. DOI : 10.2217/fmb.10.153.
C. Schär : The role of HVEM-LIGHT stimulatory signals in intestinal inflammation. ETH Zürich, 2010. DOI : 10.3929/ethz-a-006416407.
A. J. Thompson; J. Fellay; J. G. McHutchison : How the human genome can predict response to Hepatitis C therapy; Current Hepatitis Reports. 2010. DOI : 10.1007/s11901-010-0029-3.
D. H. Barouch; T. Ndung’u; G. Alter; T. Cardozo; B. Chohan et al. : Young and Early Career Investigators: Report from a Global HIV Vaccine Enterprise Working Group; Nature Precedings. 2010. DOI : 10.1038/npre.2010.4800.2.
J. Fellay; K. V. Shianna; A. Telenti; D. B. Goldstein : Host genetics and HIV-1: the final phase?; PLoS pathogens. 2010. DOI : 10.1371/journal.ppat.1001033.
W. Yoon; B.-J. Ma; J. Fellay; W. Huang; S.-M. Xia et al. : A polymorphism in the HCP5 gene associated with HLA-B*5701 does not restrict HIV-1 in vitro; AIDS. 2010. DOI : 10.1097/QAD.0b013e32833202f5.
A. J. Thompson; A. J. Muir; M. S. Sulkowski; K. Patel; H. L. Tillmann et al. : Hepatitis C trials that combine investigational agents with pegylated interferon should be stratified by interleukin-28B genotype; Hepatology. 2010. DOI : 10.1002/hep.23826.
S. Gheuens; J. Fellay; D. B. Goldstein; I. J. Koralnik : Role of human leukocyte antigen class I alleles in progressive multifocal leukoencephalopathy; Journal of neurovirology. 2010. DOI : 10.3109/13550280903552438.
K. Pelak; D. B. Goldstein; N. M. Walley; J. Fellay; D. Ge et al. : Host determinants of HIV-1 control in African Americans; The Journal of infectious diseases. 2010. DOI : 10.1086/651382.
M. Rotger; K. K. Dang; J. Fellay; E. L. Heinzen; S. Feng et al. : Genome-wide mRNA expression correlates of viral control in CD4+ T-cells from HIV-1-infected individuals; PLoS pathogens. 2010. DOI : 10.1371/journal.ppat.1000781.
J. Fellay; A. J. Thompson; D. Ge; C. E. Gumbs; T. J. Urban et al. : ITPA gene variants protect against anaemia in patients treated for chronic hepatitis C; Nature. 2010. DOI : 10.1038/nature08825.
A. J. Thompson; A. J. Muir; M. S. Sulkowski; D. Ge; J. Fellay et al. : Interleukin-28B polymorphism improves viral kinetics and is the strongest pretreatment predictor of sustained virologic response in genotype 1 hepatitis C virus; Gastroenterology. 2010. DOI : 10.1053/j.gastro.2010.04.013.
A. Specht; A. Telenti; R. Martinez; J. Fellay; E. Bailes et al. : Counteraction of HLA-C-mediated immune control of HIV-1 by Nef; Journal of virology. 2010. DOI : 10.1128/JVI.00619-10.
A. J. Thompson; J. Fellay; K. Patel; H. L. Tillmann; S. Naggie et al. : Variants in the ITPA gene protect against ribavirin-induced hemolytic anemia and decrease the need for ribavirin dose reduction; Gastroenterology. 2010. DOI : 10.1053/j.gastro.2010.06.016.
R. L. Sabado; M. O'Brien; A. Subedi; L. Qin; N. Hu et al. : Evidence of dysregulation of dendritic cells in primary HIV infection; Blood. 2010. DOI : 10.1182/blood-2010-03-273763.
K. Pelak; K. V. Shianna; D. Ge; J. M. Maia; M. Zhu et al. : The characterization of twenty sequenced human genomes; PLoS genetics. 2010. DOI : 10.1371/journal.pgen.1001111.
T. J. Urban; A. J. Thompson; S. S. Bradrick; J. Fellay; D. Schuppan et al. : IL28B genotype is associated with differential expression of intrahepatic interferon-stimulated genes in patients with chronic hepatitis C; Hepatology. 2010. DOI : 10.1002/hep.23912.
P. V. Maillard; V. Zoete; O. Michielin; D. Trono : Homology-based identification of capsid determinants that protect HIV1 from human TRIM5α restriction; The Journal of biological chemistry. 2010. DOI : 10.1074/jbc.M110.187609.
M. Friedli; I. Barde; M. Arcangeli; S. Verp; A. Quazzola et al. : A systematic enhancer screen using lentivector transgenesis identifies conserved and non-conserved functional elements at the olig1 and olig2 locus; PloS one. 2010. DOI : 10.1371/journal.pone.0015741.
N. Buchon; N. A. Broderick; T. Kuraishi; B. Lemaitre : Drosophila EGFR pathway coordinates stem cell proliferation and gut remodeling following infection; BMC biology. 2010. DOI : 10.1186/1741-7007-8-152.
Y. Bulliard; I. Narvaiza; A. Bertero; S. Peddi; U. F. Röhrig et al. : Structure-function analysis points to a polynucleotide-accommodating groove essential for APOBEC3A restriction activities; Journal of virology. 2010. DOI : 10.1128/JVI.01651-10.
I. Barde; P. Salmon; D. Trono : Production and titration of lentiviral vectors; Current protocols in neuroscience; John Wiley & Sons, 2010. p. Unit 4.21.
J. M. Chen; F. Pojer; B. Blasco; S. T. Cole : Towards anti-virulence drugs targeting ESX-1 mediated pathogenesis of Mycobacterium tuberculosis; Drug Discovery Today: Disease Mechanisms. 2010. DOI : 10.1016/j.ddmec.2010.09.002.
I. Leclercq; N. Berthet; C. Batéjat; C. Rousseaux; P. Dickinson et al. : Use of consensus sequences for the design of high density resequencing microarrays: the influenza virus paradigm; BMC genomics. 2010. DOI : 10.1186/1471-2164-11-586.
J. M. Lew; A. Kapopoulou; L. M. Jones; S. T. Cole : TubercuList - 10 years after; Tuberculosis (Edinburgh, Scotland). 2010. DOI : 10.1016/
A. Kapopoulou; J. M. Lew; S. T. Cole : The MycoBrowser portal: a comprehensive and manually annotated resource for mycobacterial genomes; Tuberculosis (Edinburgh, Scotland). 2010. DOI : 10.1016/
S. Magnet; R. C. Hartkoorn; R. Székely; J. Pató; J. A. Triccas et al. : Leads for antitubercular compounds from kinase inhibitor library screens; Tuberculosis. 2010. DOI : 10.1016/
P. A. Lang; M. Recher; N. Honke; S. Scheu; S. Borkens et al. : Tissue macrophages suppress viral replication and prevent severe immunopathology in an interferon-I-dependent manner in mice; Hepatology. 2010. DOI : 10.1002/hep.23640.
C. Trefzer; M. Rengifo-Gonzalez; M. J. Hinner; P. Schneider; V. Makarov et al. : Benzothiazinones: prodrugs that covalently modify the decaprenylphosphoryl-β-D-ribose 2'-epimerase DprE1 of Mycobacterium tuberculosis; Journal of the American Chemical Society. 2010. DOI : 10.1021/ja106357w.
I. Vallet-Gely; A. Novikov; L. Augusto; P. Liehl; G. Bolbach et al. : Association of hemolytic activity of Pseudomonas entomophila, a versatile soil bacterium, with cyclic lipopeptide production; Applied and environmental microbiology. 2010. DOI : 10.1128/AEM.02112-09.
I. Vallet-Gely; O. Opota; A. Boniface; A. Novikov; B. Lemaitre : A secondary metabolite acting as a signalling molecule controls Pseudomonas entomophila virulence; Cellular microbiology. 2010. DOI : 10.1111/j.1462-5822.2010.01501.x.
C. A. Molina-Torres; J. Castro-Garza; J. Ocampo-Candiani; M. Monot; S. T. Cole et al. : Effect of serial subculturing on the genetic composition and cytotoxic activity of Mycobacterium tuberculosis; Journal of medical microbiology. 2010. DOI : 10.1099/jmm.0.015966-0.
M. R. Pasca; G. Degiacomi; A. L. d. J. L. Ribeiro; F. Zara; P. De Mori et al. : Clinical isolates of Mycobacterium tuberculosis in four European hospitals are uniformly susceptible to benzothiazinones; Antimicrobial agents and chemotherapy. 2010. DOI : 10.1128/AAC.01676-09.
S. Bonazzi; D. Barbaras; L. Patiny; R. Scopelliti; P. Schneider et al. : Antimalarial and antitubercular nostocarboline and eudistomin derivatives: synthesis, in vitro and in vivo biological evaluation; Bioorganic & medicinal chemistry. 2010. DOI : 10.1016/j.bmc.2010.01.013.
F. Boldrin; S. Casonato; E. Dainese; C. Sala; N. Dhar et al. : Development of a repressible mycobacterial promoter system based on two transcriptional repressors; Nucleic acids research. 2010. DOI : 10.1093/nar/gkq235.
L. Dacheux; N. Berthet; G. Dissard; E. C. Holmes; O. Delmas et al. : Application of broad-spectrum resequencing microarray for genotyping rhabdoviruses; Journal of virology. 2010. DOI : 10.1128/JVI.00771-10.
G. Manina; M. Bellinzoni; M. R. Pasca; J. Neres; A. Milano et al. : Biological and structural characterization of the Mycobacterium smegmatis nitroreductase NfnB, and its role in benzothiazinone resistance; Molecular microbiology. 2010. DOI : 10.1111/j.1365-2958.2010.07277.x.
V. Salzman; S. Mondino; C. Sala; S. T. Cole; G. Gago et al. : Transcriptional regulation of lipid homeostasis in mycobacteria; Molecular microbiology. 2010. DOI : 10.1111/j.1365-2958.2010.07313.x.
C. Sala; N. Dhar; R. C. Hartkoorn; M. Zhang; Y. H. Ha et al. : A Simple Model for Testing Drugs against Non-replicating Mycobacterium tuberculosis; Antimicrobial agents and chemotherapy. 2010. DOI : 10.1128/AAC.00821-10.
R. C. Hartkoorn; C. Sala; S. J. Magnet; J. M. Chen; F. Pojer et al. : Sigma Factor F does not Prevent Rifampin Inhibition of RNA Polymerase or Cause Rifampin Tolerance in Mycobacterium tuberculosis; Journal of bacteriology. 2010. DOI : 10.1128/JB.00687-10.
A. D. Tischler; J. D. McKinney : Contrasting persistence strategies in Salmonella and Mycobacterium; Current opinion in microbiology. 2010. DOI : 10.1016/j.mib.2009.12.007.
N. Dhar; J. D. McKinney : Mycobacterium tuberculosis persistence mutants identified by screening in isoniazid-treated mice; Proceedings of the National Academy of Sciences of the United States of America. 2010. DOI : 10.1073/pnas.1003219107.
O. De Souza Silva; M. Blokesch : Genetic manipulation of Vibrio cholerae by combining natural transformation with FLP recombination; Plasmid. 2010. DOI : 10.1016/j.plasmid.2010.08.001.
I. Iacovache; M. Bischofberger; F. G. van der Goot : Structure and assembly of pore-forming proteins; Current opinion in structural biology. 2010. DOI : 10.1016/
L. Abrami; M. Bischofberger; B. Kunz; R. Groux; F. G. van der Goot : Endocytosis of the anthrax toxin is mediated by clathrin, actin and unconventional adaptors; PLoS pathogens. 2010. DOI : 10.1371/journal.ppat.1000792.
E. Laurenti; I. Barde; S. Verp; S. Offner; A. Wilson et al. : Inducible Gene and shRNA Expression in Resident Hematopoietic Stem Cells In Vivo; Stem cells (Dayton, Ohio). 2010. DOI : 10.1002/stem.460.
D. Trono; C. Van Lint; C. Rouzioux; E. Verdin; F. Barre-Sinoussi et al. : HIV Persistence and the Prospect of Long-Term Drug-Free Remissions for HIV-Infected Individuals; Science. 2010. DOI : 10.1126/science.1191047.
V. Busskamp; J. Duebel; D. Balya; M. Fradot; T. J. Viney et al. : Genetic Reactivation of Cone Photoreceptors Restores Visual Responses in Retinitis pigmentosa; Science (New York, N.Y.). 2010. DOI : 10.1126/science.1190897.
A. Massouras; K. Hens; C. Gubelmann; S. Uplekar; F. Decouttere et al. : Primer-initiated sequence synthesis to detect and assemble structural variants; Nature Methods. 2010. DOI : 10.1038/nmeth.f.308.
R. L. Marvig; M. Blokesch : Natural transformation of Vibrio cholerae as a tool - Optimizing the procedure; BMC Microbiology. 2010. DOI : 10.1186/1471-2180-10-155.
Y. Bulliard : The Interplay between Cytidine Deaminases, HIV and Domesticated Genetic Parasites. Lausanne, EPFL, 2010. DOI : 10.5075/epfl-thesis-4759.
A. C. Groner; S. Meylan; A. Ciuffi; N. Zangger; G. Ambrosini et al. : KRAB-Zinc Finger Proteins and KAP1 Can Mediate Long-Range Transcriptional Repression through Heterochromatin Spreading; PLoS genetics. 2010. DOI : 10.1371/journal.pgen.1000869.
P. V. Maillard; G. Ecco; M. Ortiz; D. Trono : The specificity of TRIM5{alpha}-mediated restriction is influenced by its coiled-coil domain; Journal of virology. 2010. DOI : 10.1128/JVI.02413-09.
S. Meylan : Genomic Context and KRAB/KAP1-mediated Transcriptional Repression. Lausanne, EPFL, 2010. DOI : 10.5075/epfl-thesis-4678.
H. M. Rowe; J. Jakobsson; D. Mesnard; J. Rougemont; S. Reynard et al. : KAP1 controls endogenous retroviruses in embryonic stem cells; Nature. 2010. DOI : 10.1038/nature08674.
P. Maillard : Innate Barriers to Genome Invasion. Lausanne, EPFL, 2010. DOI : 10.5075/epfl-thesis-4630.
L. Abrami; B. Kunz; F. G. van der Goot : Anthrax toxin triggers the activation of src-like kinases to mediate its own uptake; Proceedings of the National Academy of Sciences of the United States of America. 2010. DOI : 10.1073/pnas.0910782107.
I. Iacovache; M. Biasini; J. Kowal; W. Kukulski; M. Chami et al. : The 2DX robot: a membrane protein 2D crystallization Swiss Army knife; Journal of structural biology. 2010. DOI : 10.1016/j.jsb.2009.12.001.


A. Persat; J. G. Santiago : Electrokinetic control of sample splitting at a channel bifurcation using isotachophoresis; Nes Journal Of Physics. 2009. DOI : 10.1088/1367-2630/11/7/075026.
A. Persat; M. E. Suss; J. G. Santiago : Basic principles of electrolyte chemistry for microfluidic electrokinetics. Part II: Coupling between ion mobility, electrolysis, and acid-base equilibria; Lab on a chip. 2009. DOI : 10.1039/b906468k.
A. Persat; R. D. Chambers; J. G. Santiago : Basic principles of electrolyte chemistry for microfluidic electrokinetics. Part I: Acid-base equilibria and pH buffers; Lab on a chip. 2009. DOI : 10.1039/b906465f.
A. Persat; L. A. Marshall; J. G. Santiago : Purification of nucleic acids from whole blood using isotachophoresis; Analytical chemistry. 2009. DOI : 10.1021/ac901965v.
J. H. Jones; M. Salathé : Early assessment of anxiety and behavioral response to novel swine-origin influenza A(H1N1); PloS one. 2009. DOI : 10.1371/journal.pone.0008032.
M. Salathé; J. Van Cleve; M. W. Feldman : Evolution of stochastic switching rates in asymmetric fitness landscapes; Genetics. 2009. DOI : 10.1534/genetics.109.103333.
M. Salathé; R. D. Kouyos; S. Bonhoeffer : On the causes of selection for recombination underlying the red queen hypothesis; The American naturalist. 2009. DOI : 10.1086/599085.
R. D. Kouyos; M. Salathé; S. P. Otto; S. Bonhoeffer : The role of epistasis on the evolution of recombination in host-parasite coevolution; Theoretical population biology. 2009. DOI : 10.1016/j.tpb.2008.09.007.
V. Hornung; A. Ablasser; M. Charrel-Dennis; F. Bauernfeind; G. Horvath et al. : AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC; Nature. 2009. DOI : 10.1038/nature07725.
M. Berger; A. Ablasser; S. Kim; I. Bekeredjian-Ding; T. Giese et al. : TLR8-driven IL-12-dependent reciprocal and synergistic activation of NK cells and monocytes by immunostimulatory RNA; Journal of immunotherapy. 2009. DOI : 10.1097/CJI.0b013e318198bd2a.
A. Ablasser; H. Poeck; D. Anz; M. Berger; M. Schlee et al. : Selection of molecular structure and delivery of RNA oligonucleotides to activate TLR7 versus TLR8 and to induce high amounts of IL-12p70 in primary human monocytes; Journal of immunology (Baltimore, Md. : 1950). 2009. DOI : 10.4049/jimmunol.0803001.
A. Ablasser; F. Bauernfeind; G. Hartmann; E. Latz; K. A. Fitzgerald et al. : RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate; Nature immunology. 2009. DOI : 10.1038/ni.1779.
N. A. Broderick; B. Lemaitre : Recognition and response to microbial infection in Drosophila; Insect Infection and Immunity: Evolution, Ecology, and Mechanisms; Oxford: Oxford University Press, 2009. p. 13-33.
T. Zhang; M. Zhang; I. M. Rosenthal; J. H. Grosset; E. L. Nuermberger : Short-course therapy with daily rifapentine in a murine model of latent tuberculosis infection; American journal of respiratory and critical care medicine. 2009. DOI : 10.1164/rccm.200905-0795OC.
D. P. Welchman; S. Aksoy; F. Jiggins; B. Lemaitre : Insect immunity: from pattern recognition to symbiont-mediated host defense; Cell host & microbe. 2009. DOI : 10.1016/j.chom.2009.07.008.
J. Massacand : Shaping of mucosal dendritic cells by the intestinal environment. ETH Zürich, 2009. DOI : 10.3929/ethz-a-006023200.
G. Alter; J. Brenchley; J. Fellay : Challenges facing young investigators; IAVI report. 2009.
J. Fellay : Host genetics influences on HIV type-1 disease; Antiviral therapy. 2009. DOI : 10.3851/IMP1253.
T. J. Urban; A. C. Weintrob; J. Fellay; S. Colombo; K. V. Shianna et al. : CCL3L1 and HIV/AIDS susceptibility; Nature medicine. 2009. DOI : 10.1038/nm1009-1110.
N. M. Walley; B. Julg; S. P. Dickson; J. Fellay; D. Ge et al. : The Duffy antigen receptor for chemokines null promoter variant does not influence HIV-1 acquisition or disease progression; Cell host & microbe. 2009. DOI : 10.1016/j.chom.2009.04.011.
R. Thomas; R. Apps; Y. Qi; X. Gao; V. Male et al. : HLA-C cell surface expression and control of HIV/AIDS correlate with a variant upstream of HLA-C; Nature genetics. 2009. DOI : 10.1038/ng.486.
R. A. Siddiqui; U. Sauermann; J. Altmüller; E. Fritzer; M. Nothnagel et al. : X chromosomal variation is associated with slow progression to AIDS in HIV-1-infected women; American journal of human genetics. 2009. DOI : 10.1016/j.ajhg.2009.07.013.
D. Ge; J. Fellay; A. J. Thompson; J. S. Simon; K. V. Shianna et al. : Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance; Nature. 2009. DOI : 10.1038/nature08309.
J. Fellay; D. Ge; K. V. Shianna; S. Colombo; B. Ledergerber et al. : Common genetic variation and the control of HIV-1 in humans; PLoS genetics. 2009. DOI : 10.1371/journal.pgen.1000791.
J.-E. Dietrich; D. Trono; T. Hiiragi : Fluorescence-based promoter gene trap screen during mouse pre-implantation development. 2009. 16th Annual Conference of the International-Society-of-Development-Biologists, Edinburgh, SCOTLAND, Sep 06-10, 2009. p. S185-S185. DOI : 10.1016/j.mod.2009.06.442.
M. Kaeser; O. Gutmann; J. Hauser; T. Stinear; S. Cole et al. : Lack of Insertional-Deletional Polymorphism in a Collection of Mycobacterium ulcerans Isolates from Ghanaian Buruli Ulcer Patients; Journal Of Clinical Microbiology. 2009. DOI : 10.1128/JCM.00760-09.
G. van der Goot : Getting the Opportunity to Fly on your own; Chimia. 2009. DOI : 10.2533/chimia.2009.862.
A. Defaye; I. Evans; M. Crozatier; W. Wood; B. Lemaitre et al. : Genetic ablation of Drosophila phagocytes reveals their contribution to both development and resistance to bacterial infection; Journal of innate immunity. 2009. DOI : 10.1159/000210264.
N. Buchon; N. A. Broderick; M. Poidevin; S. Pradervand; B. Lemaitre : Drosophila intestinal response to bacterial infection: activation of host defense and stem cell proliferation; Cell host & microbe. 2009. DOI : 10.1016/j.chom.2009.01.003.
K.-B. Roh; C.-H. Kim; H. Lee; H.-M. Kwon; J.-W. Park et al. : Proteolytic cascade for the activation of the insect toll pathway induced by the fungal cell wall component; The Journal of biological chemistry. 2009. DOI : 10.1074/jbc.M109.007419.
N. Buchon; M. Poidevin; H.-M. Kwon; A. Guillou; V. Sottas et al. : A single modular serine protease integrates signals from pattern-recognition receptors upstream of the Drosophila Toll pathway; Proceedings of the National Academy of Sciences of the United States of America. 2009. DOI : 10.1073/pnas.0901924106.
N. Buchon; N. A. Broderick; S. Chakrabarti; B. Lemaitre : Invasive and indigenous microbiota impact intestinal stem cell activity through multiple pathways in Drosophila; Genes & development. 2009. DOI : 10.1101/gad.1827009.
P. Geuking; R. Narasimamurthy; B. Lemaitre; K. Basler; F. Leulier : A non-redundant role for Drosophila Mkk4 and hemipterous/Mkk7 in TAK1-mediated activation of JNK; PloS one. 2009. DOI : 10.1371/journal.pone.0007709.
M. Gendrin; D. P. Welchman; M. Poidevin; M. Hervé; B. Lemaitre : Long-range activation of systemic immunity through peptidoglycan diffusion in Drosophila; PLoS pathogens. 2009. DOI : 10.1371/journal.ppat.1000694.
C. Sala; D. C. Grainger; S. T. Cole : Dissecting regulatory networks in host-pathogen interaction using chIP-on-chip technology; Cell host & microbe. 2009. DOI : 10.1016/j.chom.2009.04.007.
C. Sala; A. Haouz; F. A. Saul; I. Miras; I. Rosenkrands et al. : Genome-wide regulon and crystal structure of BlaI (Rv1846c) from Mycobacterium tuberculosis; Molecular microbiology. 2009. DOI : 10.1111/j.1365-2958.2008.06583.x.
L. Alvey; S. Prado; B. Saint-Joanis; S. Michel; M. Koch et al. : Diversity-oriented synthesis of furo[3,2-f]chromanes with antimycobacterial activity; European journal of medicinal chemistry. 2009. DOI : 10.1016/j.ejmech.2009.01.017.
M. C. Garcia Pelayo; S. Uplekar; A. Keniry; P. Mendoza Lopez; T. Garnier et al. : A comprehensive survey of single nucleotide polymorphisms (SNPs) across Mycobacterium bovis strains and M. bovis BCG vaccine strains refines the genealogy and defines a minimal set of SNPs that separate virulent M. bovis strains and M. bovis BCG strains; Infection and immunity. 2009. DOI : 10.1128/IAI.01099-08.
V. Makarov; G. Manina; K. Mikusova; U. Möllmann; O. Ryabova et al. : Benzothiazinones kill Mycobacterium tuberculosis by blocking arabinan synthesis; Science (New York, N.Y.). 2009. DOI : 10.1126/science.1171583.
C. Buchrieser; S. T. Cole : From functional genomics to systems (micro)biology; Current opinion in microbiology. 2009. DOI : 10.1016/j.mib.2009.09.001.
W. Bitter; E. N. G. Houben; D. Bottai; P. Brodin; E. J. Brown et al. : Systematic genetic nomenclature for type VII secretion systems; PLoS pathogens. 2009. DOI : 10.1371/journal.ppat.1000507.
T. Christophe; M. Jackson; H. K. Jeon; D. Fenistein; M. Contreras-Dominguez et al. : High content screening identifies decaprenyl-phosphoribose 2' epimerase as a target for intracellular antimycobacterial inhibitors; PLoS pathogens. 2009. DOI : 10.1371/journal.ppat.1000645.
M. Monot; N. Honoré; T. Garnier; N. Zidane; D. Sherafi et al. : Comparative genomic and phylogeographic analysis of Mycobacterium leprae; Nature genetics. 2009. DOI : 10.1038/ng.477.
G. van der Goot; J. A. T. Young : Receptors of anthrax toxin and cell entry; Molecular aspects of medicine. 2009. DOI : 10.1016/j.mam.2009.08.007.
M. Feldman; F. G. van der Goot : Novel ubiquitin-dependent quality control in the endoplasmic reticulum; Trends in cell biology. 2009. DOI : 10.1016/j.tcb.2009.05.005.
M. Bischofberger; M. R. Gonzalez; F. G. van der Goot : Membrane injury by pore-forming proteins; Current opinion in cell biology. 2009. DOI : 10.1016/
N. Dupont; S. Lacas-Gervais; J. Bertout; I. Paz; B. Freche et al. : Shigella phagocytic vacuolar membrane remnants participate in the cellular response to pathogen invasion and are regulated by autophagy; Cell host & microbe. 2009. DOI : 10.1016/j.chom.2009.07.005.
O. Menzel; J. Birraux; B. E. Wildhaber; C. Jond; F. Lasne et al. : Biosafety in ex vivo gene therapy and conditional ablation of lentivirally transduced hepatocytes in nonhuman primates; Molecular therapy : the journal of the American Society of Gene Therapy. 2009. DOI : 10.1038/mt.2009.143.
S. Meylan; D. Trono : Innate immunity against retroviral pathogens: from an ambiguous genetic self to novel therapeutic approaches; Swiss Med Wkly. 2009.
J. C. Massacand; R. C. Stettler; R. Meier; N. E. Humphreys; R. K. Grencis et al. : Helminth products bypass the need for TSLP in Th2 immune responses by directly modulating dendritic cell function; Proc Natl Acad Sci U S A. 2009. DOI : 10.1073/pnas.0906367106.
F. Santoni de Sio; D. Trono : APOBEC3G-depleted resting CD4+ T cells remain refractory to HIV1 infection; PLoS One. 2009. DOI : 10.1371/journal.pone.0006571.
Y. Bulliard; P. Turelli; U. Röhrig; V. Zoete; B. Mangeat et al. : Functional analysis and structural modeling of human APOBEC3G reveal the role of evolutionarily conserved elements in the inhibition of human immunodeficiency virus type 1 infection and Alu transposition; Journal of Virology. 2009. DOI : 10.1128/JVI.01491-09.
I. Barde; E. Laurenti; S. Verp; A. C. Groner; C. Towne et al. : Regulation of Episomal Gene Expression by KRAB/KAP1-Mediated Histone Modifications; Journal of Virology. 2009. DOI : 10.1128/JVI.00001-09.
J. Deuquet; L. Abrami; A. Difeo; M. C. M. Ramirez; J. A. Martignetti et al. : Systemic hyalinosis mutations in the CMG2 ectodomain leading to loss of function through retention in the endoplasmic reticulum; Human mutation. 2009. DOI : 10.1002/humu.20872.
M.-O. Sauvain : Studies on lentiviral-mediated transgenesis. Lausanne, EPFL, 2009. DOI : 10.5075/epfl-thesis-4281.


M. Salathé; R. D. Kouyos; S. Bonhoeffer : The state of affairs in the kingdom of the Red Queen; Trends in ecology & evolution. 2008. DOI : 10.1016/j.tree.2008.04.010.
M. Salathé; S. Bonhoeffer : The effect of opinion clustering on disease outbreaks; Journal of the Royal Society, Interface / the Royal Society. 2008. DOI : 10.1098/rsif.2008.0271.
M. Salathé; R. D. Kouyos; R. R. Regoes; S. Bonhoeffer : Rapid parasite adaptation drives selection for high recombination rates; Evolution; international journal of organic evolution. 2008. DOI : 10.1111/j.1558-5646.2007.00265.x.
M. Salathé; O. S. Soyer : Parasites lead to evolution of robustness against gene loss in host signaling networks; Molecular systems biology. 2008. DOI : 10.1038/msb.2008.44.
I. M. Rosenthal; M. Zhang; D. Almeida; J. H. Grosset; E. L. Nuermberger : Isoniazid or moxifloxacin in rifapentine-based regimens for experimental tuberculosis?; American journal of respiratory and critical care medicine. 2008. DOI : 10.1164/rccm.200807-1029OC.
S. Colombo; A. Rauch; M. Rotger; J. Fellay; R. Martinez et al. : The HCP5 single-nucleotide polymorphism: a simple screening tool for prediction of hypersensitivity reaction to abacavir; The Journal of infectious diseases. 2008. DOI : 10.1086/591184.
D. Ge; K. Zhang; A. C. Need; O. Martin; J. Fellay et al. : WGAViewer: software for genomic annotation of whole genome association studies; Genome research. 2008. DOI : 10.1101/gr.071571.107.
C. Sala; F. Forti; F. Magnoni; D. Ghisotti : The katG mRNA of Mycobacterium tuberculosis and Mycobacterium smegmatis is processed at its 5 ' end and is stabilized by both a polypurine sequence and translation initiation; Bmc Molecular Biology. 2008. DOI : 10.1186/1471-2199-9-33.
B. Ryall; H. Nasser; B. Lemaitre; D. Mossialos; H. D. Williams : Cyanogenesis in Pseudomonas entomophila: an entomopathogenic bacterium. 2008. Joint Conference of the 33rd FEBS Congress/11th IUBMB Conference, Athens, GREECE, Jun 28-Jul 03, 2008. p. 289-289.
F. Leulier; B. Lemaitre : Toll-like receptors--taking an evolutionary approach; Nature reviews. Genetics. 2008. DOI : 10.1038/nrg2303.
I. Vallet-Gely; B. Lemaitre; F. Boccard : Bacterial strategies to overcome insect defences; Nature reviews. Microbiology. 2008. DOI : 10.1038/nrmicro1870.
Y. Romeo; B. Lemaitre : Drosophila immunity: methods for monitoring the activity of Toll and Imd signaling pathways; Methods in molecular biology (Clifton, N.J.). 2008. DOI : 10.1007/978-1-59745-570-1_22.
B. Lemaitre; F. M. Ausubel : Animal models for host-pathogen interactions; Current opinion in microbiology. 2008. DOI : 10.1016/j.mib.2008.05.002.
N. Lhocine; P. S. Ribeiro; N. Buchon; A. Wepf; R. Wilson et al. : PIMS modulates immune tolerance by negatively regulating Drosophila innate immune signaling; Cell host & microbe. 2008. DOI : 10.1016/j.chom.2008.07.004.
C. Scherfer; H. Tang; Z. Kambris; N. Lhocine; C. Hashimoto et al. : Drosophila Serpin-28D regulates hemolymph phenoloxidase activity and adult pigmentation; Developmental biology. 2008. DOI : 10.1016/j.ydbio.2008.08.030.
H. Tang; Z. Kambris; B. Lemaitre; C. Hashimoto : A serpin that regulates immune melanization in the respiratory system of Drosophila; Developmental cell. 2008. DOI : 10.1016/j.devcel.2008.08.017.
S. Quevillon-Cheruel; N. Leulliot; C. A. Muniz; M. Vincent; J. Gallay et al. : Evf, a virulence factor produced by the Drosophila pathogen Erwinia carotovora, is an S-palmitoylated protein with a new fold that binds to lipid vesicles; The Journal of biological chemistry. 2008. DOI : 10.1074/jbc.M808334200.
T. S. Balganesh; P. M. Alzari; S. T. Cole : Rising standards for tuberculosis drug development; Trends in pharmacological sciences. 2008. DOI : 10.1016/
C. Demangel; T. P. Stinear; S. T. Cole : Buruli ulcer: reductive evolution enhances pathogenicity of Mycobacterium ulcerans; Nature reviews. Microbiology. 2008. DOI : 10.1038/nrmicro2077.
S. Sinha; S. Arora; K. Kosalai; A. Namane; A. S. Pym et al. : Proteome analysis of the plasma membrane of Mycobacterium tuberculosis; Comparative and functional genomics. 2008. DOI : 10.1002/cfg.211.
R. Székely; F. Wáczek; I. Szabadkai; G. Németh; B. Hegymegi-Barakonyi et al. : A novel drug discovery concept for tuberculosis: inhibition of bacterial and host cell signalling; Immunology letters. 2008. DOI : 10.1016/j.imlet.2007.12.005.
W. Frigui; D. Bottai; L. Majlessi; M. Monot; E. Josselin et al. : Control of M. tuberculosis ESAT-6 secretion and specific T cell recognition by PhoP; PLoS pathogens. 2008. DOI : 10.1371/journal.ppat.0040033.
T. P. Stinear; T. Seemann; P. F. Harrison; G. A. Jenkin; J. K. Davies et al. : Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis; Genome research. 2008. DOI : 10.1101/gr.075069.107.
M. Monot; N. Honoré; C. Balière; B. Ji; S. Sow et al. : Are variable-number tandem repeats appropriate for genotyping Mycobacterium leprae?; Journal of clinical microbiology. 2008. DOI : 10.1128/JCM.00239-08.
P. Tafelmeyer; C. Laurent; P. Lenormand; J.-C. Rousselle; L. Marsollier et al. : Comprehensive proteome analysis of Mycobacterium ulcerans and quantitative comparison of mycolactone biosynthesis; Proteomics. 2008. DOI : 10.1002/pmic.200701018.
L. Alvey; S. Prado; V. Huteau; B. Saint-Joanis; S. Michel et al. : A new synthetic access to furo[3,2-f]chromene analogues of an antimycobacterial; Bioorganic & medicinal chemistry. 2008. DOI : 10.1016/j.bmc.2008.06.057.
N. Berthet; A. K. Reinhardt; I. Leclercq; S. van Ooyen; C. Batéjat et al. : Phi29 polymerase based random amplification of viral RNA as an alternative to random RT-PCR; BMC molecular biology. 2008. DOI : 10.1186/1471-2199-9-77.
K. J. McLean; P. Carroll; D. G. Lewis; A. J. Dunford; H. E. Seward et al. : Characterization of active site structure in CYP121: A cytochrome P450 essential for viability of Mycobacterium tuberculosis H37Rv; The Journal of biological chemistry. 2008. DOI : 10.1074/jbc.M802115200.
S. Savvi; D. F. Warner; B. D. Kana; J. D. McKinney; V. Mizrahi et al. : Functional characterization of a vitamin B12-dependent methylmalonyl pathway in Mycobacterium tuberculosis: implications for propionate metabolism during growth on fatty acids; Journal of bacteriology. 2008. DOI : 10.1128/JB.01767-07.
J. Charollais; F. G. Van Der Goot : Palmitoylation of membrane proteins (Review); Molecular membrane biology. 2008. DOI : 10.1080/09687680802620369.
M. Bischofberger; F. G. van der Goot : Exotoxin secretion: getting out to find the way in; Cell host & microbe. 2008. DOI : 10.1016/j.chom.2007.12.003.
N. Genoud; D. Ott; N. Braun; M. Prinz; P. Schwarz et al. : Antiprion prophylaxis by gene transfer of a soluble prion antagonist; The American journal of pathology. 2008. DOI : 10.2353/ajpath.2008.070836.
C. Roduit; F. G. van der Goot; P. De Los Rios; A. Yersin; P. Steiner et al. : Elastic membrane heterogeneity of living cells revealed by stiff nanoscale membrane domains; Biophysical Journal. 2008. DOI : 10.1529/biophysj.107.112862.
K. D. McCoy; M. Stoel; R. Stettler; P. Merky; K. Fink et al. : Polyclonal and specific antibodies mediate protective immunity against enteric helminth infection; Cell Host & Microbe. 2008. DOI : 10.1016/j.chom.2008.08.014.
J. C. Massacand; P. Kaiser; B. Ernst; A. Tardivel; K. Burki et al. : Intestinal bacteria condition dendritic cells to promote IgA production; PLoS One. 2008. DOI : 10.1371/journal.pone.0002588.
B. J. Marsland; M. Kurrer; R. Reissmann; N. L. Harris; M. Kopf : Nippostrongylus brasiliensis infection leads to the development of emphysema associated with the induction of alternatively activated macrophages; Eur J Immunol. 2008. DOI : 10.1002/eji.200737827.
P. A. Lang; C. Contaldo; P. Georgiev; A. M. El-Badry; M. Recher et al. : Aggravation of viral hepatitis by platelet-derived serotonin; Nat Med. 2008. DOI : 10.1038/nm1780.
A. K. Heer; N. L. Harris; M. Kopf; B. J. Marsland : CD4+ and CD8+ T cells exhibit differential requirements for CCR7-mediated antigen transport during influenza infection; Journal of Immunology. 2008.
M. Blokesch; G. K. Schoolnik : The extracellular nuclease Dns and its role in natural transformation of Vibrio cholerae; Journal of Bacteriology. 2008. DOI : 10.1128/JB.00959-08.
J. Jakobsson; M. I. Cordero; R. Bisaz; A. C. Groner; V. Busskamp et al. : KAP1-mediated epigenetic repression in the forebrain modulates behavioral vulnerability to stress; Neuron. 2008. DOI : 10.1016/j.neuron.2008.09.036.
K. Meyer; J. Marquis; J. Trüb; R. Nlend Nelend; S. Verp et al. : Rescue of a severe mouse model for spinal muscular atrophy by U7 snRNA-mediated splicing modulation; Hum Mol Genet. 2008. DOI : 10.1093/hmg/ddn382.
M. Asparuhova; I. Barde; D. Trono; K. Schranz; D. Schümperli : Development and characterization of a triple combination gene therapy vector inhibiting HIV-1 multiplication; J Gene Med. 2008. DOI : 10.1002/jgm.1238.
M. R. Gonzalez; M. Bischofberger; L. Pernot; F. G. van der Goot; B. Frêche : Bacterial pore-forming toxins: the (w)hole story?; Cell Mol Life Sci. 2008. DOI : 10.1007/s00018-007-7434-y.
I. Iacovache; F. G. van der Goot; L. Pernot : Pore formation: an ancient yet complex form of attack; Biochim Biophys Acta. 2008. DOI : 10.1016/j.bbamem.2008.01.026.
L. Abrami; B. Kunz; J. Deuquet; A. Bafico; G. Davidson et al. : Functional interactions between anthrax toxin receptors and the WNT signalling protein LRP6; Cell Microbiol. 2008. DOI : 10.1111/j.1462-5822.2008.01226.x.
L. Abrami; B. Kunz; I. Iacovache; F. G. van der Goot : Palmitoylation and ubiquitination regulate exit of the Wnt signaling protein LRP6 from the endoplasmic reticulum; Proc Natl Acad Sci U S A. 2008. DOI : 10.1073/pnas.0710389105.
L. J. Bischof; C. Y. Kao; F. C. Los; M. R. Gonzalez; Z. Shen et al. : Activation of the unfolded protein response is required for defenses against bacterial pore-forming toxin in vivo; PLoS Pathog. 2008. DOI : 10.1371/journal.ppat.1000176.
C. Lafourcade; K. Sobo; S. Kieffer-Jaquinod; J. Garin; F. G. van der Goot : Regulation of the V-ATPase along the endocytic pathway occurs through reversible subunit association and membrane localization; PLoS ONE. 2008. DOI : 10.1371/journal.pone.0002758.
V. Pons; P. P. Luyet; E. Morel; L. Abrami; F. G. van der Goot et al. : Hrs and SNX3 functions in sorting and membrane invagination within multivesicular bodies; PLoS Biol. 2008. DOI : 10.1371/journal.pbio.0060214.
N. Reig; A. Jiang; R. Couture; F. S. Sutterwala; Y. Ogura et al. : Maturation modulates caspase-1-independent responses of dendritic cells to Anthrax lethal toxin; Cell Microbiol. 2008. DOI : 10.1111/j.1462-5822.2008.01121.x.
F. Diaz-Griffero; M. Perron; K. McGee-Estrada; R. Hanna; P. V. Maillard et al. : A human TRIM5alpha B30.2/SPRY domain mutant gains the ability to restrict and prematurely uncoat B-tropic murine leukemia virus; Virology. 2008. DOI : 10.1016/j.virol.2008.05.008.
D. Bach; S. Peddy; B. Mangeat; A. Lakkaraju; K. Strub et al. : Characterization of APOBEC3G binding to 7SL RNA; Retrovirology. 2008. DOI : 10.1186/1742-4690-5-54.
M.-O. Sauvain; A. P. Dorr; B. Stevenson; A. Quazzola; F. Naef et al. : Genotypic features of lentivirus transgenic mice; Journal of virology. 2008. DOI : 10.1128/JVI.00623-08.
P. Turelli; A. Liagre-Quazzola; B. Mangeat; S. Verp; S. Jost et al. : APOBEC3-independent interferon-induced viral clearance in hepatitis B virus transgenic mice; Journal of Virology. 2008. DOI : 10.1128/JVI.00216-08.


R. D. Kouyos; M. Salathé; S. Bonhoeffer : The Red Queen and the persistence of linkage-disequilibrium oscillations in finite and infinite populations; BMC evolutionary biology. 2007. DOI : 10.1186/1471-2148-7-211.
M. Salathé : The evolution of complexity on the level of genes, individuals and populations. Ecole Polytechnique Fédérale de Zürich (ETHZ), 2007. DOI : 10.3929/ethz-a-005364513.
S. T. Cole; P. M. Alzari : Towards new tuberculosis drugs. 2007. Focus Topic at Life Sciences 2007 Conference, Glasgow, SCOTLAND, Jul 09-12, 2007. p. 1321-1324.
I. M. Rosenthal; M. Zhang; K. N. Williams; C. A. Peloquin; S. Tyagi et al. : Daily dosing of rifapentine cures tuberculosis in three months or less in the murine model; PLoS medicine. 2007. DOI : 10.1371/journal.pmed.0040344.
J. Fellay; D. B. Goldstein : Host genetics: fine-tuning innate signaling; Current biology. 2007. DOI : 10.1016/j.cub.2007.04.052.
O. Keiser; J. Fellay; M. Opravil; H. H. Hirsch; B. Hirschel et al. : Adverse events to antiretrovirals in the Swiss HIV Cohort Study: effect on mortality and treatment modification; Antiviral therapy. 2007.
O. Manuel; J.-P. Venetz; J. Fellay; J.-B. Wasserfallen; N. Sturzenegger et al. : Efficacy and safety of universal valganciclovir prophylaxis combined with a tacrolimus/mycophenolate-based regimen in kidney transplantation; Swiss medical weekly. 2007.
J. Fellay; K. V. Shianna; D. Ge; S. Colombo; B. Ledergerber et al. : A whole-genome association study of major determinants for host control of HIV-1; Science. 2007. DOI : 10.1126/science.1143767.
B. Lemaitre; J. Hoffmann : The host defense of Drosophila melanogaster; Annual review of immunology. 2007. DOI : 10.1146/annurev.immunol.25.022106.141615.
A. Wehenkel; M. Bellinzoni; M. Graña; R. Duran; A. Villarino et al. : Mycobacterial Ser/Thr protein kinases and phosphatases: physiological roles and therapeutic potential; Biochimica et biophysica acta. 2007. DOI : 10.1016/j.bbapap.2007.08.006.
S. T. Cole; P. M. Alzari : Towards new tuberculosis drugs; Biochemical Society transactions. 2007. DOI : 10.1042/BST0351321.
S. Prado; Y. L. Janin; B. Saint-Joanis; P. Brodin; S. Michel et al. : Synthesis and antimycobacterial evaluation of benzofurobenzopyran analogues; Bioorganic & medicinal chemistry. 2007. DOI : 10.1016/j.bmc.2006.12.009.
T. P. Stinear; T. Seemann; S. Pidot; W. Frigui; G. Reysset et al. : Reductive evolution and niche adaptation inferred from the genome of Mycobacterium ulcerans, the causative agent of Buruli ulcer; Genome research. 2007. DOI : 10.1101/gr.5942807.
L. Marsollier; E. Deniaux; P. Brodin; A. Marot; C. M. Wondje et al. : Protection against Mycobacterium ulcerans lesion development by exposure to aquatic insect saliva; PLoS medicine. 2007. DOI : 10.1371/journal.pmed.0040064.
R. Brosch; S. V. Gordon; T. Garnier; K. Eiglmeier; W. Frigui et al. : Genome plasticity of BCG and impact on vaccine efficacy; Proceedings of the National Academy of Sciences of the United States of America. 2007. DOI : 10.1073/pnas.0700869104.
J. Teutschbein; G. Schumann; U. Möllmann; S. Grabley; S. T. Cole et al. : A protein linkage map of the ESAT-6 secretion system 1 (ESX-1) of Mycobacterium tuberculosis; Microbiological research. 2007. DOI : 10.1016/j.micres.2006.11.016.
L. Marsollier; P. Brodin; M. Jackson; J. Korduláková; P. Tafelmeyer et al. : Impact of Mycobacterium ulcerans biofilm on transmissibility to ecological niches and Buruli ulcer pathogenesis; PLoS pathogens. 2007. DOI : 10.1371/journal.ppat.0030062.
E. Coutanceau; J. Decalf; A. Martino; A. Babon; N. Winter et al. : Selective suppression of dendritic cell functions by Mycobacterium ulcerans toxin mycolactone; The Journal of experimental medicine. 2007. DOI : 10.1084/jem.20070234.
M. I. de Jonge; G. Pehau-Arnaudet; M. M. Fretz; F. Romain; D. Bottai et al. : ESAT-6 from Mycobacterium tuberculosis dissociates from its putative chaperone CFP-10 under acidic conditions and exhibits membrane-lysing activity; Journal of bacteriology. 2007. DOI : 10.1128/JB.00469-07.
M. Graña; A. Haouz; A. Buschiazzo; I. Miras; A. Wehenkel et al. : The crystal structure of M. leprae ML2640c defines a large family of putative S-adenosylmethionine-dependent methyltransferases in mycobacteria; Protein science : a publication of the Protein Society. 2007. DOI : 10.1110/ps.072982707.
M. Casenghi; S. T. Cole; C. F. Nathan : New approaches to filling the gap in tuberculosis drug discovery; PLoS medicine. 2007. DOI : 10.1371/journal.pmed.0040293.
M.-L. Chesne-Seck; N. Barilone; F. Boudou; J. Gonzalo Asensio; P. E. Kolattukudy et al. : A point mutation in the two-component regulator PhoP-PhoR accounts for the absence of polyketide-derived acyltrehaloses but not that of phthiocerol dimycocerosates in Mycobacterium tuberculosis H37Ra; Journal of bacteriology. 2007. DOI : 10.1128/JB.01465-07.
N. Dhar; J. D. McKinney : Microbial phenotypic heterogeneity and antibiotic tolerance; Current opinion in microbiology. 2007. DOI : 10.1016/j.mib.2006.12.007.
A. M. Upton; J. D. McKinney : Role of the methylcitrate cycle in propionate metabolism and detoxification in Mycobacterium smegmatis; Microbiology (Reading, England). 2007. DOI : 10.1099/mic.0.2007/011726-0.
P. Small; F. G. van der Goot : Editorial overview; Curr Opin Microbiol. 2007.
R. Aroian; F. G. van der Goot : Pore-forming toxins and cellular non-immune defenses (CNIDs); Current opinion in microbiology. 2007. DOI : 10.1016/j.mib.2006.12.008.
B. Freche; N. Reig; F. G. van der Goot : The role of the inflammasome in cellular responses to toxins and bacterial effectors; Seminars in immunopathology. 2007. DOI : 10.1007/s00281-007-0085-0.
K.-L. Zhang; B. Mangeat; M. Ortiz; V. Zoete; D. Trono et al. : Model Structure of Human APOBEC3G; PLoS ONE. 2007. DOI : 10.1371/journal.pone.0000378.
A. Malashicheva; B. Kanzler; E. Tolkunova; D. Trono; A. Tomilin : Lentivirus as a tool for lineage-specific gene manipulations; genesis. 2007. DOI : 10.1002/dvg.20313.
A. Rideau; B. Mangeat; T. Matthes; D. Trono; P. Beris : Molecular mechanism of hepcidin deficiency in a patient with juvenile hemochromatosis; Haematologica. 2007. DOI : 10.3324/haematol.10545.
M. B. Asparuhova; G. Marti; S. Liu; F. Serhan; D. Trono et al. : Inhibition of HIV-1 multiplication by a modified U7 snRNA inducing Tat and Rev exon skipping; The journal of gene medicine. 2007. DOI : 10.1002/jgm.1027.
A. G. Dayer; B. Jenny; M.-O. Sauvain; G. Potter; P. Salmon et al. : Expression of FGF-2 in neural progenitor cells enhances their potential for cellular brain repair in the rodent cortex; Brain : a journal of neurology. 2007. DOI : 10.1093/brain/awm200.
A. Frohlich; B. J. Marsland; I. Sonderegger; M. Kurrer; M. R. Hodge et al. : IL-21 receptor signaling is integral to the development of Th2 effector responses in vivo; Blood. 2007. DOI : 10.1182/blood-2006-05-021600.
S. Freigang; B. Eschli; N. Harris; M. Geuking; K. Quirin et al. : A lymphocytic choriomeningitis virus glycoprotein variant that is retained in the endoplasmic reticulum efficiently cross-primes CD8(+) T cell responses; Proc Natl Acad Sci U S A. 2007. DOI : 10.1073/pnas.0704423104.
M. Blokesch; G. K. Schoolnik : Serogroup conversion of Vibrio cholerae in aquatic reservoirs; PLoS pathogens. 2007. DOI : 10.1371/journal.ppat.0030081.
X. Li; D. Kaloyanova; M. van Eijk; R. Eerland; G. van der Goot et al. : Involvement of a Golgi-resident GPI-anchored protein in maintenance of the Golgi structure; Mol Biol Cell. 2007. DOI : 10.1091/mbc.E06-03-0236.
K. Sobo; J. Chevallier; R. G. Parton; J. Gruenberg; F. G. van der Goot : Diversity of raft-like domains in late endosomes; PLoS ONE. 2007. DOI : 10.1371/journal.pone.0000391.
K. Sobo; I. Le Blanc; P. P. Luyet; M. Fivaz; C. Ferguson et al. : Late endosomal cholesterol accumulation leads to impaired intra-endosomal trafficking; PLoS ONE. 2007. DOI : 10.1371/journal.pone.0000851.
P. Maillard; S. Reynard; F. Serhan; P. Turelli; D. Trono : Interfering residues narrow the spectrum of MLV restriction by human TRIM5alpha; PLOS Pathogens. 2007. DOI : 10.1371/journal.ppat.0030200.
M. Wiznerowicz; J. Jakobsson; J. Szulc; S. Liao; A. Quazzola et al. : The KRAB repressor domain can trigger de novo promoter methylation during mouse early embryogenesis; Journal of Biological Chemistry. 2007. DOI : 10.1074/jbc.M705898200.
S. Jost : Polynucleotide cytidine deaminases, innate immunity and hepatitis B infection. Lausanne, EPFL, 2007. DOI : 10.5075/epfl-thesis-3975.
S. Jost; P. Turelli; B. Mangeat; U. Protzer; D. Trono : Induction of antiviral cytidine deaminases does not explain the inhibition of hepatitis B virus replication by interferons; J. Virol.. 2007. DOI : 10.1128/JVI.02489-06.


O. S. Soyer; M. Salathé; S. Bonhoeffer : Signal transduction networks: topology, response and biochemical processes; Journal of theoretical biology. 2006. DOI : 10.1016/j.jtbi.2005.05.030.
M. Salathé; M. Ackermann; S. Bonhoeffer : The effect of multifunctionality on the rate of evolution in yeast; Molecular biology and evolution. 2006. DOI : 10.1093/molbev/msj086.
M. Salathé; R. Salathé; P. Schmid-Hempel; S. Bonhoeffer : Mutation accumulation in space and the maintenance of sexual reproduction; Ecology letters. 2006. DOI : 10.1111/j.1461-0248.2006.00942.x.
A. Scherer; M. Salathé; S. Bonhoeffer : High epitope expression levels increase competition between T cells; PLoS computational biology. 2006. DOI : 10.1371/journal.pcbi.0020109.
M. Salathé : Sexual selection and its effect on the fixation of an asexual clone; Biology letters. 2006. DOI : 10.1098/rsbl.2006.0529.
I. Bekeredjian-Ding; S. I. Roth; S. Gilles; T. Giese; A. Ablasser et al. : T cell-independent, TLR-induced IL-12p70 production in primary human monocytes; Journal of immunology (Baltimore, Md. : 1950). 2006.
J. Bangham; F. Jiggins; B. Lemaitre : Insect immunity: the post-genomic era; Immunity. 2006. DOI : 10.1016/j.immuni.2006.07.002.
J. Fellay; M. Cavassini : [HIV-AIDS: answers to new questions]; Revue médicale suisse. 2006.
N. J. Müller; H. Furrer; L. Kaiser; B. Hirschel; M. Cavassini et al. : HIV and solid organ transplantation: the Swiss experience; Swiss medical weekly. 2006.
I.-H. Jang; N. Chosa; S.-H. Kim; H.-J. Nam; B. Lemaitre et al. : A Spätzle-processing enzyme required for toll signaling activation in Drosophila innate immunity; Developmental cell. 2006. DOI : 10.1016/j.devcel.2005.11.013.
S. Brun; S. Vidal; P. Spellman; K. Takahashi; H. Tricoire et al. : The MAPKKK Mekk1 regulates the expression of Turandot stress genes in response to septic injury in Drosophila; Genes to cells : devoted to molecular & cellular mechanisms. 2006. DOI : 10.1111/j.1365-2443.2006.00953.x.
A. Zaidman-Rémy; M. Hervé; M. Poidevin; S. Pili-Floury; M.-S. Kim et al. : The Drosophila amidase PGRP-LB modulates the immune response to bacterial infection; Immunity. 2006. DOI : 10.1016/j.immuni.2006.02.012.
Z. Kambris; S. Brun; I.-H. Jang; H.-J. Nam; Y. Romeo et al. : Drosophila immunity: a large-scale in vivo RNAi screen identifies five serine proteases required for Toll activation; Current biology : CB. 2006. DOI : 10.1016/j.cub.2006.03.020.
C. Scherfer; M. R. Qazi; K. Takahashi; R. Ueda; M. S. Dushay et al. : The Toll immune-regulated Drosophila protein Fondue is involved in hemolymph clotting and puparium formation; Developmental biology. 2006. DOI : 10.1016/j.ydbio.2006.03.019.
N. Vodovar; D. Vallenet; S. Cruveiller; Z. Rouy; V. Barbe et al. : Complete genome sequence of the entomopathogenic and metabolically versatile soil bacterium Pseudomonas entomophila; Nature biotechnology. 2006. DOI : 10.1038/nbt1212.
P. Liehl; M. Blight; N. Vodovar; F. Boccard; B. Lemaitre : Prevalence of local immune response against oral infection in a Drosophila/Pseudomonas infection model; PLoS pathogens. 2006. DOI : 10.1371/journal.ppat.0020056.
H. Tang; Z. Kambris; B. Lemaitre; C. Hashimoto : Two proteases defining a melanization cascade in the immune system of Drosophila; The Journal of biological chemistry. 2006. DOI : 10.1074/jbc.M601642200.
F. Leulier; N. Lhocine; B. Lemaitre; P. Meier : The Drosophila inhibitor of apoptosis protein DIAP2 functions in innate immunity and is essential to resist gram-negative bacterial infection; Molecular and cellular biology. 2006. DOI : 10.1128/MCB.00548-06.
C. Acosta Muniz; D. Jaillard; B. Lemaitre; F. Boccard : Erwinia carotovora Evf antagonizes the elimination of bacteria in the gut of Drosophila larvae; Cellular microbiology. 2006. DOI : 10.1111/j.1462-5822.2006.00771.x.
L. Majlessi; M. Simsova; Z. Jarvis; P. Brodin; M.-J. Rojas et al. : An increase in antimycobacterial Th1-cell responses by prime-boost protocols of immunization does not enhance protection against tuberculosis; Infection and immunity. 2006. DOI : 10.1128/IAI.74.4.2128-2137.2006.
S. Prado; H. Ledeit; S. Michel; M. Koch; J. C. Darbord et al. : Benzofuro[3,2-f][1]benzopyrans: a new class of antitubercular agents; Bioorganic & medicinal chemistry. 2006. DOI : 10.1016/j.bmc.2006.03.033.
E. Coutanceau; P. Legras; L. Marsollier; G. Reysset; S. T. Cole et al. : Immunogenicity of Mycobacterium ulcerans Hsp65 and protective efficacy of a Mycobacterium leprae Hsp65-based DNA vaccine against Buruli ulcer; Microbes and infection / Institut Pasteur. 2006. DOI : 10.1016/j.micinf.2006.03.009.
R. Aráoz; N. Honoré; S. Banu; C. Demangel; Y. Cissoko et al. : Towards an immunodiagnostic test for leprosy; Microbes and infection / Institut Pasteur. 2006. DOI : 10.1016/j.micinf.2006.04.002.
B. Saint-Joanis; C. Demangel; M. Jackson; P. Brodin; L. Marsollier et al. : Inactivation of Rv2525c, a substrate of the twin arginine translocation (Tat) system of Mycobacterium tuberculosis, increases beta-lactam susceptibility and virulence; Journal of bacteriology. 2006. DOI : 10.1128/JB.00631-06.
P. Fernandez; B. Saint-Joanis; N. Barilone; M. Jackson; B. Gicquel et al. : The Ser/Thr protein kinase PknB is essential for sustaining mycobacterial growth; Journal of bacteriology. 2006. DOI : 10.1128/JB.00963-06.
L. Marsollier; J.-P. S. André; W. Frigui; G. Reysset; G. Milon et al. : Early trafficking events of Mycobacterium ulcerans within Naucoris cimicoides; Cellular microbiology. 2006. DOI : 10.1111/j.1462-5822.2006.00790.x.
W. Shepard; A. Haouz; M. Graña; A. Buschiazzo; J.-M. Betton et al. : The crystal structure of Rv0813c from Mycobacterium tuberculosis reveals a new family of fatty acid-binding protein-like proteins in bacteria; Journal of bacteriology. 2006. DOI : 10.1128/JB.01435-06.
E. J. Muñoz-Elías; A. M. Upton; J. Cherian; J. D. McKinney : Role of the methylcitrate cycle in Mycobacterium tuberculosis metabolism, intracellular growth, and virulence; Molecular microbiology. 2006. DOI : 10.1111/j.1365-2958.2006.05155.x.
R. M. Owens; F. F. Hsu; B. C. VanderVen; G. E. Purdy; E. Hesteande et al. : M. tuberculosis Rv2252 encodes a diacylglycerol kinase involved in the biosynthesis of phosphatidylinositol mannosides (PIMs); Molecular microbiology. 2006. DOI : 10.1111/j.1365-2958.2006.05174.x.
J. Timm; N. Kurepina; B. N. Kreiswirth; F. A. Post; G. B. Walther et al. : A multidrug-resistant, acr1-deficient clinical isolate of Mycobacterium tuberculosis is unimpaired for replication in macrophages; The Journal of infectious diseases. 2006. DOI : 10.1086/504526.
T. A. Gould; H. van de Langemheen; E. J. Muñoz-Elías; J. D. McKinney; J. C. Sacchettini : Dual role of isocitrate lyase 1 in the glyoxylate and methylcitrate cycles in Mycobacterium tuberculosis; Molecular microbiology. 2006. DOI : 10.1111/j.1365-2958.2006.05297.x.
J. Gruenberg; F. G. van der Goot : Toxoplasma: guess who's coming to dinner; Cell. 2006. DOI : 10.1016/j.cell.2006.03.029.
Y. Ariumi; D. Trono : Ataxia-telangiectasia-mutated (ATM) protein can enhance human immunodeficiency virus type 1 replication by stimulating Rev function; Journal of Virology. 2006. DOI : 10.1128/JVI.80.5.2445-2452.2006.
T. H. Nguyen; J. Birraux; B. Wildhaber; A. Myara; F. Trivin et al. : Ex vivo lentivirus transduction and immediate transplantation of uncultured hepatocytes for treating hyperbilirubinemic Gunn rat; Transplantation. 2006. DOI : 10.1097/
M. Eberhardt; P. Salmon; M.-A. von Mach; J. G. Hengstler; M. Brulport et al. : Multipotential nestin and Isl-1 positive mesenchymal stem cells isolated from human pancreatic islets; Biochemical and Biophysical Research Communications. 2006. DOI : 10.1016/j.bbrc.2006.05.016.

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