You will find below the list of all publications related to the Global Health Institute at the School of Life Sciences.
Should you want to select specific publications by topics or authors, please use the EPFL scientific publications search engine.
2024
A First-in-Human Randomized Study to Assess the Safety, Tolerability, Pharmacokinetics, and Neutralization Profile of Two Investigational Long-Acting Anti-SARS-CoV-2 Monoclonal Antibodies
Infectious Diseases and Therapy. 2024-01-14. DOI : 10.1007/s40121-023-00908-9.Control of nuclear envelope dynamics during acute ER stress by LINC complexes disassembly and selective, asymmetric autophagy of the outer nuclear membrane
Autophagy. 2024-01-04. DOI : 10.1080/15548627.2023.2299123.A Cluster of Evolutionarily Recent KRAB Zinc Finger Proteins Protects Cancer Cells from Replicative Stress–Induced Inflammation
Cancer Research. 2024. p. OF1-OF19. DOI : 10.1158/0008-5472.CAN-23-1237.Reply to Dages et al: You AIn’t using it right-artificial intelligence progress in allergy
Journal Of Allergy And Clinical Immunology. 2024-01-01. Vol. 153, num. 1, p. 355-356. DOI : 10.1016/j.jaci.2023.09.023.Rescue of secretion of rare-disease-associated misfolded mutant glycoproteins in UGGT1 knock-out mammalian cells
Traffic. 2024-01-01. Vol. 25, num. 1, p. e12927. DOI : 10.1111/tra.12927.Genome sequences of Vibrio cholerae strains isolated in the DRC between 2009 and 2012
Microbiology Resource Announcements. 2024. DOI : 10.1128/mra.00827-23.Transposable elements mediate genetic effects altering the expression of nearby genes in colorectal cancer
Nature Communications. 2024. Vol. 15, num. 749. DOI : 10.1038/s41467-023-42405-0.Ancestral genome reconstruction enhances transposable element annotation by identifying degenerate integrants
Cell Genomics. 2024. Vol. 4, p. 100497. DOI : 10.1016/j.xgen.2024.100497.Meeting our Makers: Uncovering the cis-regulatory activity of transposable elements using statistical learning
Lausanne, EPFL, 2024.Single-cell analysis of the interactions between Mycobacterium tuberculosis and macrophages
Lausanne, EPFL, 2024.Exploring the role of cGAS-STING-mediated inflammation in age-associated neurodegeneration and antitumor immunity
Lausanne, EPFL, 2024.Deconvolution of ex-vivo drug screening data and bulk tissue expression predicts the abundance and viability of cancer cell subpopulations
Lausanne, EPFL, 2024.2023
Reanalysis of mtDNA mutations of human primordial germ cells (PGCs) reveals NUMT contamination and suggests that selection in PGCs may be positive
Mitochondrion. 2023-12-16. Vol. 74, p. 101817. DOI : 10.1016/j.mito.2023.10.005.The HLA-B*57:01 allele corresponds to a very large MHC haploblock likely explaining its massive effect for HIV-1 elite control
Frontiers In Immunology. 2023-12-11. Vol. 14, p. 1305856. DOI : 10.3389/fimmu.2023.1305856.Predicting type 2 diabetes risk before and after solid organ transplantation using polygenic scores in a Danish cohort
Frontiers In Molecular Biosciences. 2023-12-07. Vol. 10, p. 1282412. DOI : 10.3389/fmolb.2023.1282412.Genomics of Preaxostyla Flagellates Illuminates the Path Towards the Loss of Mitochondria
Plos Genetics. 2023-12-01. Vol. 19, num. 12, p. e1011050. DOI : 10.1371/journal.pgen.1011050.Basic Mechanisms of Immunometabolites in Shaping the Immune Response
Journal Of Innate Immunity. 2023-11-23. DOI : 10.1159/000535452.Tau accumulation in degradative organelles is associated to lysosomal stress
Scientific Reports. 2023-10-21. Vol. 13, num. 1, p. 18024. DOI : 10.1038/s41598-023-44979-7.PSGL-1 is an evolutionarily conserved antiviral restriction factor
Mbio. 2023-10-03. p. e0038723. DOI : 10.1128/mbio.00387-23.Toxic Effects of Koumine on the Early-Life Development Stage of Zebrafish
Toxics. 2023-10-01. Vol. 11, num. 10, p. 853. DOI : 10.3390/toxics11100853.Refining S-acylation: Structure, regulation, dynamics, and therapeutic implications
Journal Of Cell Biology. 2023-09-27. Vol. 222, num. 11, p. e202307103. DOI : 10.1083/jcb.202307103.Inborn Errors of Type I Interferon Immunity in Patients with Severe Acute Hepatitis E
2023-09-11. p. 14S-14S.Inflammatory mitochondrial nucleic acids as drivers of pathophysiology
Clinical And Translational Medicine. 2023-09-01. Vol. 13, num. 9, p. e1403. DOI : 10.1002/ctm2.1403.Amidation of glutamate residues in mycobacterial peptidoglycan is essential for cell wall cross-linking
Frontiers In Cellular And Infection Microbiology. 2023-08-24. Vol. 13, p. 1205829. DOI : 10.3389/fcimb.2023.1205829.Archaeal type IV pili stabilize Haloferax volcanii biofilms in flow
Current Biology. 2023-08-07. Vol. 33, num. 15, p. 3265-3271. DOI : 10.1016/j.cub.2023.06.055.Investigating the composition and recruitment of the mycobacterial ImuA’-ImuB-DnaE2 mutasome
Elife. 2023-08-02. Vol. 12, p. e75628. DOI : 10.7554/eLife.75628.Africa-specific human genetic variation near CHD1L associates with HIV-1 load
Nature. 2023-08-02. Vol. 620, p. 1025–1030. DOI : 10.1038/s41586-023-06370-4.cGAS-STING drives ageing-related inflammation and neurodegeneration
Nature. 2023-08-02. Vol. 620, p. 374–380. DOI : 10.1038/s41586-023-06373-1.Variation in African genomes linked to control of HIV
Nature. 2023-08-02. DOI : 10.1038/d41586-023-02277-2.Pseudomonas aeruginosa type IV pili actively induce mucus contraction to form biofilms in tissue-engineered human airways
Plos Biology. 2023-08-01. Vol. 21, num. 8, p. e3002209. DOI : 10.1371/journal.pbio.3002209.Protein target highlights in CASP15: Analysis of models by structure providers
Proteins-Structure Function And Bioinformatics. 2023-07-26. DOI : 10.1002/prot.26545.A metagenome-wide association study of HIV disease progression in HIV controllers
Iscience. 2023-07-21. Vol. 26, num. 7, p. 107214. DOI : 10.1016/j.isci.2023.107214.Ecology-relevant bacteria drive the evolution of host antimicrobial peptides in Drosophila
Science. 2023-07-21. Vol. 381, num. 6655, p. eadg5725. DOI : 10.1126/science.adg5725.Prevalence of CFTR variants in primary immunodeficiency patients with bronchiectasis is an important modifying cofactor
Journal Of Allergy And Clinical Immunology. 2023-07-01. Vol. 152, num. 1, p. 257-265. DOI : 10.1016/j.jaci.2023.01.035.Hits and Misses: Digital Contact Tracing in a Pandemic
Perspectives On Psychological Science. 2023-06-30. DOI : 10.1177/17456916231179365.Autoantibodies neutralizing type I IFNs underlie West Nile virus encephalitis in & SIM;40% of patients
Journal Of Experimental Medicine. 2023-06-22. Vol. 220, num. 9, p. e20230661. DOI : 10.1084/jem.20230661.Fluid flow structures gut microbiota biofilm communities by distributing public goods
Proceedings Of The National Academy Of Sciences Of The United States Of America. 2023-06-20. Vol. 120, num. 25, p. e2217577120. DOI : 10.1073/pnas.2217577120.TMX4-driven LINC complex disassembly and asymmetric autophagy of the nuclear envelope upon acute ER stress
Nature Communications. 2023-06-13. Vol. 14, num. 1, p. 3497. DOI : 10.1038/s41467-023-39172-3.ER-to-lysosome-associated degradation in a nutshell: mammalian, yeast, and plant ER-phagy as induced by misfolded proteins
Febs Letters. 2023-06-10. DOI : 10.1002/1873-3468.14674.Biofilm formation on human immune cells is a multicellular predation strategy of Vibrio cholerae
Cell. 2023-06-08. Vol. 186, num. 12, p. 2690-+. DOI : 10.1016/j.cell.2023.05.008.Multiancestry sex-stratified genomic associations with HIV viral load and controller status from the ICGH
Jci Insight. 2023-06-08. Vol. 8, num. 11, p. 170068. DOI : 10.1172/jci.insight.170068.Poloxamers Have Vaccine-Adjuvant Properties by Increasing Dissemination of Particulate Antigen at Distant Lymph Nodes
Molecules. 2023-06-01. Vol. 28, num. 12, p. 4778. DOI : 10.3390/molecules28124778.Association of a Polygenic Risk Score With Osteoporosis in People Living With HIV: The Swiss HIV Cohort Study
Journal Of Infectious Diseases. 2023-05-24. DOI : 10.1093/infdis/jiad179.A polygenic risk score to predict sudden cardiac arrest in patients with cardiovascular disease
2023-05-11. 55th European-Society-of-Human-Genetics (ESHG) Conference, Vienna, AUSTRIA, JUN 11-14, 2022. p. 691-691.Deamination of adenine to guanine is a signature of oxidative damage in mitochondrial DNA
2023-05-11. 55th European-Society-of-Human-Genetics (ESHG) Conference, Vienna, AUSTRIA, JUN 11-14, 2022. p. 648-648.Host genomic susceptibility to severe respiratory syncytial virus infection
2023-05-11. 55th European-Society-of-Human-Genetics (ESHG) Conference, Vienna, AUSTRIA, JUN 11-14, 2022. p. 163-164.A polygenic risk score improves the prediction of cardiovascular risk associated with obstructive sleep-apnoea
2023-05-11. 55th European-Society-of-Human-Genetics (ESHG) Conference, Vienna, AUSTRIA, JUN 11-14, 2022. p. 145-146.Secondary structure of the human mitochondrial genome affects formation of deletions
Bmc Biology. 2023-05-08. Vol. 21, num. 1, p. 103. DOI : 10.1186/s12915-023-01606-1.Viral Genetic Determinants of Prolonged Respiratory Syncytial Virus Infection Among Infants in a Healthy Term Birth Cohort
Journal Of Infectious Diseases. 2023-05-01. Vol. 227, num. 10, p. 1194-1202. DOI : 10.1093/infdis/jiac442.Epigenetic ageing accelerates before antiretroviral therapy and decelerates after viral suppression in people with HIV in Switzerland: a longitudinal study over 17 years
Lancet Healthy Longevity. 2023-05-01. Vol. 4, num. 5, p. E211-E218. DOI : 10.1016/S2666-7568(23)00037-5.Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19
Genome Medicine. 2023-04-05. Vol. 15, num. 1, p. 22. DOI : 10.1186/s13073-023-01173-8.Cryo-EM structures and binding of mouse and human ACE2 to SARS-CoV-2 variants of concern indicate that mutations enabling immune escape could expand host range
PLOS Pathogens. 2023-04-05. Vol. 19, num. 4, p. e1011206. DOI : 10.1371/journal.ppat.1011206.Antimicrobial peptides do not directly contribute to aging in Drosophila, but improve lifespan by preventing dysbiosis
Disease Models & Mechanisms. 2023-04-01. Vol. 16, num. 4, p. dmm049965. DOI : 10.1242/dmm.049965.Back-to-Africa introductions of Mycobacterium tuberculosis as the main cause of tuberculosis in Dar es Salaam, Tanzania
Plos Pathogens. 2023-04-01. Vol. 19, num. 4, p. e1010893. DOI : 10.1371/journal.ppat.1010893.Uptake-independent killing of macrophages by extracellular Mycobacterium tuberculosis aggregates
Embo Journal. 2023-03-15. DOI : 10.15252/embj.2023113490.COVID-Twitter-BERT: A natural language processing model to analyse COVID-19 content on Twitter
Frontiers In Artificial Intelligence. 2023-03-14. Vol. 6, p. 1023281. DOI : 10.3389/frai.2023.1023281.Live Birth of a Healthy Child in a Couple with Identical mtDNA Carrying a Pathogenic c.471_477delTTTAAAAinsG Variant in the MOCS2 Gene
Genes. 2023-03-01. Vol. 14, num. 3, p. 720. DOI : 10.3390/genes14030720.An Advanced Alkaline Al-Air Fuel Cell Using L-Ascorbic Acid Interface Layer upon Al Anode via Gradient Anti-corrosion
Acs Sustainable Chemistry & Engineering. 2023-02-22. DOI : 10.1021/acssuschemeng.3c00214.Two antagonistic response regulators control Pseudomonas aeruginosa polarization during mechanotaxis
Embo Journal. 2023-02-16. DOI : 10.15252/embj.2022112165.Material Substrate Physical Properties Control Pseudomonas aeruginosa Biofilm Architecture
Mbio. 2023-02-14. DOI : 10.1128/mbio.03518-22.Associations of genetic and infectious risk factors with coronary heart disease
Elife. 2023-02-14. Vol. 12, p. e79742. DOI : 10.7554/eLife.79742.Species-specific regulation of XIST by the JPX/FTX orthologs
Nucleic Acids Research. 2023-02-02. DOI : 10.1093/nar/gkad029.Leukocyte Count and Coronary Artery Disease Events in People With Human Immunodeficiency Virus: A Longitudinal Study
Clinical Infectious Diseases. 2023-01-23. DOI : 10.1093/cid/ciad033.Combining European and US risk prediction models with polygenic risk scores to refine cardiovascular prevention: the CoLaus|PsyCoLaus Study
European Journal Of Preventive Cardiology. 2023-01-18. DOI : 10.1093/eurjpc/zwad012.Dynamics of CLIMP-63 S-acylation control ER morphology
Nature Communications. 2023-01-17. Vol. 14, num. 1. DOI : 10.1038/s41467-023-35921-6.Statistical learning quantifies transposable element-mediated cis-regulation
Genome Biology. 2023. Vol. 24, num. 258. DOI : 10.1186/s13059-023-03085-7.SARS-CoV-2 hijacks a cell damage response, which induces transcription of a more efficient Spike S-acyltransferase
Nature Communications. 2023. Vol. 14, num. 7302. DOI : 10.1038/s41467-023-43027-2.New ingredients for old recipes
Nature Genetics. 2023. DOI : 10.1038/s41588-023-01591-9.The Effects of Spatial Organization and Fluid Flow on the Social Interactions in Microbial Communities
Lausanne, EPFL, 2023.Interactions between pili affect the outcome of bacterial competition driven by the type VI secretion system
bioRxiv. 2023. p. 61. DOI : 10.1101/2023.10.25.564063.Broadly potent anti-SARS-CoV-2 antibody shares 93% of epitope with ACE2 and provides full protection in monkeys
Journal of Infection. 2023. DOI : 10.1016/j.jinf.2023.10.008.Functional characterization of Drosophila melanogaster immune effectors
Lausanne, EPFL, 2023.Take a walk on the KRAB side
Trends in Genetics. 2023. DOI : 10.1016/j.tig.2023.08.003.Genetic features and genomic targets of human KRAB-zinc finger proteins
Genome Research. 2023. DOI : 10.1101/gr.277722.123.Host-Pathogen Interactions Through the Genomic Lens
Lausanne, EPFL, 2023.KRAB zinc finger proteins link heterochromatin maintenance to replicative stress and inflammation in diffuse large B-cell lymphoma
Lausanne, EPFL, 2023.Efficient and sensitive profiling of RNA–protein interactions using TLC-CLIP
Nucleic Acids Research. 2023. DOI : 10.1093/nar/gkad466.DNA modifications impact natural transformation of Acinetobacter baumannii
Nucleic Acids Research. 2023. Vol. gkad377. DOI : 10.1093/nar/gkad377.Sporadic type VI secretion in seventh pandemic Vibrio cholerae
Microbiology. 2023. Vol. 169, num. 5. DOI : 10.1099/mic.0.001329.The immunopeptidome landscape associated with T cell infiltration, inflammation and immune editing in lung cancer
Nature Cancer. 2023. DOI : 10.1038/s43018-023-00548-5.Bacterial colonization in realistic environments: how mechanics impact biofilm formation in the wild and during infection
Lausanne, EPFL, 2023.Machine Learning in Protein Science De Novo Design of Site-Specific Protein Binders Using Surface Fingerprints
2023-01-01. 36th Annual Symposium of the Protein-Society, San Francisco, CA, Jul 07-10, 2022.Biofilm morphogenesis on soft hydrogels
Lausanne, EPFL, 2023.Tracking spatiotemporal localisation and interactions of the innate immune sensor STING
Lausanne, EPFL, 2023.Recombinant bacteria resistant to horizontal gene transfer and phage infection
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