Segmentation Timing and Dynamics Laboratory
How do spatio-temporal patterns emerge at the tissue level from noisy cellular and molecular interactions? What are the principles that govern transitions from parts to wholes, and those that determine precision and robustness? We explore these issues using a population of genetic oscillators in the vertebrate embryo termed the segmentation clock.
VIDEO – 15 somite stage zebrafish embryo imaged in a Light Sheet Microscope. We show a max projection of the histone marker (in grey) and the a segmentation clock marker, Her1 (in magenta)