We are interested in understanding how biological patterning and function emerge from microscopic molecular interactions. Our primary focus is on the problems of flow generation by arrays of active filaments (cilia) and extreme cellular mechanics. By studying diverse organisms, we aim to elucidate the biophysical mechanisms that link cilia patterning with flow generation and cytoskeletal geometry with cellular mechanics. Our research is highly interdisciplinary and combines approaches from cell and developmental biology, engineering, fluid mechanics and soft matter physics.