Ligand-Directed Site-Selective Cysteine Bioconjugation of the KELCH Domain of KEAP1 with Hypervalent Iodine Reagents

C. A. J. Marty; X. Ji; S. Nicolai; C. Heinis; J. Waser 

Cycloaddition and Annulation Reactions with Donor‐Acceptor Cyclobutanes

E. G. L. Robert; J. Waser 

Peptide/Protein Functionalization and Macrocyclization via Alkyne Umpolung with Hypervalent Iodine Reagents

X. Liu; J. Waser 

Peptide‐Carbazolyl Cyanobenzene Conjugates: Enabling Biomolecule Functionalization via Photoredox and Energy Transfer Catalysis

X-Y. Lui; W. Cai; A-S. Chauvin; B. Fierz; J. Waser 

Synthesis of Bicyclo[1.1.1]pentane Z‐Substituted Enamides, Enol Ethers, and Vinyl Sulfides Using Iodine (III) Reagents

N. Lee; J. Dechent; E. Grinhagena; J. Waser 

Enantioselective Synthesis of 1,2-disubstituted Thiocyclobutanes via Michael Addition

E. G. L. Robert; J. Waser 

Unlocking σ-Type Cyclopropenium Cation Transfer Reactions by an Iodine(III)-Based Umpolung Strategy

X. Li; J. Waser 

Photocatalyzed Azidofunctionalization of Alkenes via Radical-Polar Crossover

P. Palamini; A. A. Schöpfer; J. Waser 

Beginning of Second Mandate as Editors-in-Chief for Helvetica Chimica Acta

E. Hevia; J. Waser 

Diastereoselective Synthesis of N-Heterocycle Substituted Cyclobutanes via Michael Addition onto Cyclobutenes

E. G. L. Robert; J. Waser 

Homologation of Alkenyl Carbonyls via a Cyclopropanation/Light-Mediated Selective CÀ C Cleavage Strategy

V. T. T. Nguyen; D. K. Brownsey; A. Bossonnet; M. Wodrich; J. Waser 

Forging 1,1′-Bicyclopropenyls by Synergistic Au/Ag Dual-Catalyzed Cyclopropenyl Cross-Coupling

X. Li; J. Waser 

Cost-informed Bayesian reaction optimization †

A. A. Schoepfer; J. Weinreich; R. Laplaza; J. Waser; C. Corminboeuf 

Enamine Synthesis via Regiocontrolled 6-endo-dig and 5-exo-dig Tethered Carboamination of Propargylic Alcohols

H. Solé Àvila; M. Purins; L. Eichenberger; J. Waser 

Photocatalytic Decarboxylative Functionalization of Cyclopropenes via Cyclopropenium Cation Intermediates

V. Smyrnov; J. Waser 

Platinum-Catalyzed Isomerization of Cyclopropenes to 1,3-Dienes

V. Smyrnov; A. Homassel; L. Choudhury; J. Waser 

Ficini Reaction with Acrylates for the Stereoselective Synthesis of Aminocyclobutanes

Emma G. L. Robert; J. Waser 

Hypervalent Iodine Amino Acid Building Blocks for Bioorthogonal Peptide Macrocyclization

X-Y. Liu; O. Mykhailenko; A. Faraone; J. Waser 

Lewis acid catalyzed [4+2] annulation of bicyclobutanes with dienol ethers for the synthesis of bicyclo[4.1.1]octanes

S. Nicolai; J. Waser 

Accessing elusive σ-type cyclopropenium cation equivalents through redox gold catalysis

X. Li; M. D. Wodrich; J. Waser 

Organic Dye Photocatalyzed Synthesis of Functionalized Lactones and Lactams via a Cyclization-Alkynylation Cascade

D. Cavalli; J. Waser 

SOMOphilic alkyne vs radical-polar crossover approaches: The full story of the azido-alkynylation of alkenes

J. A. Borrel; J. Waser 

Silylium-Catalyzed Activation of DonorAcceptor Strained Rings and Annulation with Indoles

E. G. L. Robert; J. Waser 

Benzylic C(sp3)-H Azidation: Copper vs Iron Catalysis

A. Renteria-Gomez; R. O. Torres-Ochoa; P. Palamini; R. Simonet-Davin; Q. Wang et al. 

Quantitative Description of Metal Center Organization and Interactions in Single-Atom Catalysts (Adv. Mater. 5/2024)

K. Rossi; A. Ruiz-Ferrando; D. F. Akl; V. G. Abalos; J. Heras-Domingo et al. 

Interrupted Polonovski Strategy for the Synthesis of Functionalized Amino Acids and Peptides

C. Marty; E. M. D. Allouche; J. Waser 

Cysteine-Cysteine Cross-Conjugation of both Peptides and Proteins with a Bifunctional Hypervalent Iodine-Electrophilic Reagent

I. Koutsopetras; A. K. Mishra; R. Benazza; O. Hernandez-Alba; S. Cianferani et al. 

Azido-alkynylation of alkenes through radical-polar crossover

J. Borrel; J. Waser 

Synthesis of Trifluoromethylated Alkenes: Hypervalent Iodine Meets High-Valent Copper

T. M. Milzarek; J. Waser 

Peptide-Hypervalent Iodine Reagent Chimeras: Enabling Peptide Functionalization and Macrocyclization

X-Y. Liu; X. Ji; C. Heinis; J. Waser 

Synthesis of propargyl silanes from terminal alkynes via a migratory Sonogashira reaction

M. Purins; L. Eichenberger; J. Waser 

Donor-Acceptor Aminocyclobutane Monoesters: Synthesis and Silylium-Catalyzed (4+2) Annulation with Indoles

E. G. L. Robert; V. Pirenne; M. D. Wodrich; J. Waser 

Sustainable production of chemicals

J. Perez-Ramirez; J. Waser; M. F. Lagadec; S. Mitchell; L. Gamp 

Copper (I)‐BOX Catalyzed Asymmetric 3‐Component Reaction for the Synthesis of Trifluoromethylated Propargylic Ethers and Anilines**

N. P. Ramirez Hernandez; J. Waser 

Photochemical [2+2] Cycloaddition of Alkynyl Boronates

O. S. Liashuk; O. O. Grygorenko; Y. M. Volovenko; J. Waser 

One-pot synthesis of functionalized bis(trifluoromethylated)benziodoxoles from iodine(i) precursors

T. M. Milzarek; N. P. Ramirez; X-Y. Liu; J. Waser 

Acyl-Ethynylbenziodoxolone (acyl-EBX): Access to Ketene Dithioarylacetals

P. Palamini; J. Borrel; M. Djaïd; M. Delattre; J. Waser 

Iron-Catalyzed Synthesis of α-Azido α-Amino Esters via the Alkylazidation of Alkenes

P. Palamini; E. M. D. Allouche; J. Waser 

Semipinacol Rearrangement of Cyclopropenylcarbinols for the Synthesis of Highly Substituted Cyclopropanes

V. Smyrnov; J. Waser 

Synthesis of Fluorescent Cyclic Peptides via Gold(I)-Catalyzed Macrocyclization

X-Y. Liu; W. Cai; N. Ronceray; A. Radenovic; B. Fierz et al. 

Photocatalyzed [2σ + 2σ] and [2σ + 2π] Cycloadditions for the Synthesis of Bicyclo[3.1.1]heptanes and 5- or 6-Membered Carbocycles

T. V. T. Nguyen; A. Bossonnet; M. D. Wodrich; J. Waser 

Exploring Photoredox-Catalyzed (Re)functionalizations with Core-Modified Benziodoxolones

S. G. E. Amos; F. Le Vaillant; J. Waser 

Substrate-controlled C-H or C-C alkynylation of cyclopropanes: generation of aryl radical cations by direct light activation of hypervalent iodine reagents

T. V. T. Nguyen; M. D. Wodrich; J. Waser 

Tyrosine bioconjugation with hypervalent iodine

N. Declas; J. R. J. Maynard; L. Menin; N. Gasilova; S. Goetze et al. 

Copper-Catalyzed Alkynylation of Hydrazides: An Easy Access to Functionalized Azadipeptides

E. Le Du; J. Borrel; J. Waser 

(4+3) Annulation of Donor-Acceptor Cyclopropanes and Azadienes: Highly Stereoselective Synthesis of Azepanones

S. Nicolai; J. Waser 

Pd(II)-Catalyzed Aminoacetoxylation of Alkenes Via Tether Formation

T. Rossolini; A. Das; S. Nicolai; J. Waser 

Palladium-Catalyzed trans-Hydroalkoxylation: Counterintuitive Use of an Aryl Iodide Additive to Promote C-H Bond Formation

A. Das; L. Buzzetti; M. Purins; J. Waser 

N-Terminal Selective C-H Azidation of Proline-Containing Peptides: a Platform for Late-Stage Diversification

E. M. D. Allouche; R. Simonet-Davin; J. Waser 

Synthesis of polycyclic aminal heterocycles via decarboxylative cyclisation of dipeptide derivatives

E. G. L. Robert; E. Le Du; J. Waser 

Asymmetric Cyclopropanation and Epoxidation via a Catalytically Formed Chiral Auxiliary

M. Purins; J. Waser 

Tosyloxybenziodoxolone: A Platform for Performing the Umpolung of Alkynes in One-Pot Transformations

J. Borrel; J. Waser 

Direct Photoexcitation of Ethynylbenziodoxolones: An Alternative to Photocatalysis for Alkynylation Reactions**

S. G. E. Amos; D. Cavalli; F. Le Vaillant; J. Waser 

Diamine Synthesis via the Nitrogen-Directed Azidation of sigma- and pi-C-C Bonds

M-M. Wang; T. V. T. Nguyen; J. Waser 

Cu(I)-Catalyzed gem-Aminoalkynylation of Diazo Compounds: Synthesis of Fluorinated Propargylic Amines

N. P. Ramirez; G. Pisella; J. Waser 

Synthesis of Quinolines via the Metal-free Visible-Light-Mediated Radical Azidation of Cyclopropenes

V. Smyrnov; B. Muriel; J. Waser 

Amphiphilic Iodine(III) Reagents for the Lipophilization of Peptides in Water

A. K. Mishra; R. Tessier; D. P. Hari; J. Waser 

Inhibition of Thiol‐Mediated Uptake with Irreversible Covalent Inhibitors

B. Lim; Y. Cheng; T. Kato; A. Pham; E. Le Du et al. 

Solar and Visible Light Assisted Peptide Synthesis

A. K. Mishra; G. Parvari; S. K. Santra; A. Bazylevich; O. Dorfman et al. 

Structure and Reactivity of N-Heterocyclic Alkynyl Hypervalent Iodine Reagents

E. Le Du; T. Duhail; M. D. Wodrich; R. Scopelliti; F. Fadaei-Tirani et al. 

Catalytic (3+2) annulation of donor-acceptor aminocyclopropane monoesters and indoles

V. Pirenne; E. G. L. Robert; J. Waser 

Cys-Cys and Cys-Lys Stapling of Unprotected Peptides Enabled by Hypervalent Iodine Reagents

J. Ceballos; E. Grinhagena; G. Sangouard; C. Heinis; J. Waser 

Small peptide diversification through photoredox-catalyzed oxidative C-terminal modification

E. Le Du; M. Garreau; J. Waser 

Low‐Temperature Intramolecular [4+2] Cycloaddition of Allenes with Arenes for the Synthesis of Diene Ligands

D. P. Hari; G. Pisella; M. D. Wodrich; A. V. Tsymbal; F. F. Tirani et al. 

Synthesis of Thiochromans via [3+3] Annulation of Aminocyclopropanes with Thiophenols

M-M. Wang; S. Jeon; J. Waser 

Azide Radical Initiated Ring Opening of Cyclopropenes Leading to Alkenyl Nitriles and Polycyclic Aromatic Compounds

B. Muriel; J. Waser 

Photocatalytic Umpolung of N- and O-substituted alkenes for the synthesis of 1,2-amino alcohols and diols

S. G. E. Amos; S. Nicolai; J. Waser 

Enantioselective Carboetherification/Hydrogenation for the Synthesis of Amino Alcohols via a Catalytically Formed Chiral Auxiliary

L. Buzzetti; M. Purins; P. D. G. Greenwood; J. Waser 

Ori-Pixel, a Multi-DoFs Origami Pixel for Modular Reconfigurable Surfaces

M. Salerno; J. Paik; S. Mintchev 

Polynomial Evaluation on Superscalar Architecture, Applied to the Elementary Function e(x)

T. Ewart; F. Cremonesi; F. Schurmann; F. Delalondre 

Photochemical Functionalization of Heterocycles with EBX Reagents: C-H Alkynylation versus Deconstructive Ring Cleavage

E. Voutyritsa; M. Garreau; M. G. Kokotou; I. Triandafillidi; J. Waser et al. 

Oxidative Fluorination of Cyclopropylamides through Organic Photoredox Catalysis

M-M. Wang; J. Waser 

Access to Vinyl Ethers and Ketones with Hypervalent Iodine Reagents as Oxy-Allyl Cation Synthetic Equivalents

N. Declas; J. Waser 

Triazene-Activated Donor–Acceptor Cyclopropanes: Ring-Opening and (3 + 2) Annulation Reactions

A. A. Suleymanov; E. Le Du; Z. Dong; B. Muriel; R. Scopelliti et al. 

Copper-Catalyzed Oxyvinylation of Diazo Compounds

G. Pisella; A. Gagnebin; J. Waser 

Ethynylation of Cysteine Residues: From Peptides to Proteins in Vitro and in Living Cells

R. Tessier; R. K. Nandi; B. G. Dwyer; D. Abegg; C. Sornay et al. 

Three-Component Reaction for the Synthesis of Highly Functionalized Propargyl Ethers

G. Pisella; A. Gagnebin; J. Waser 

Copper-Catalyzed Oxyalkynylation of C-S Bonds in Thiiranes and Thiethanes with Hypervalent Iodine Reagents

J. Borrel; G. Pisella; J. Waser 

One-Pot Synthesis of 1-[(Triisopropylsilyl)ethynyl]-1,2-benziodoxol-3(1H)-one (TIPS-EBX): Process Safety Assessment and Impact of Impurities on Product Stability

D. P. Hari; P. Caramenti; L. Schouwey; M. Chang; S. Nicolai et al. 

Synthesis of bicyclo[3.1.0]hexanes by (3+2) annulation of cyclopropenes with aminocyclopropanes

B. Muriel; A. Gagnebin; J. Waser 

Alkynylation of radicals: spotlight on the “Third Way” to transfer triple bonds

F. Le Vaillant; J. Waser 

1,3-Difunctionalization of Aminocyclopropanes via Dielectrophilic Intermediates

M-M. Wang; J. Waser 

An Alternative One-Electron Oxidation Strategy to Access Hypervalent Iodine Reagents

J. Ceballos; M. Garreau; J. Waser 

Palladium-Catalyzed Carboxy-Alkynylation of Propargylic Amines Using Carbonate Salts as Carbon Dioxide Source

P. D. G. Greenwood; J. Waser 

“Doubly Orthogonal” Labeling of Peptides and Proteins

R. Tessier; J. Ceballos; N. Guidotti; R. Simonet-Davin; B. Fierz et al. 

C-Terminal Bioconjugation of Peptides through Photoredox Catalyzed Decarboxylative Alkynylation

M. Garreau; F. Le Vaillant; J. Waser 

Ethynylbenziodazolones (EBZ) as Electrophilic Alkynylation Reagents for the Highly Enantioselective Copper-Catalyzed Oxyalkynylation of Diazo Compounds

D. P. Hari; L. Schouwey; V. Barber; R. Scopelliti; F. Fadaei-Tirani et al. 

Stereoselective synthesis of alkyl-, aryl-, vinyl- and alkynyl-substituted Z-enamides and enol ethers

P. Caramenti; N. Declas; R. Tessier; M. D. Wodrich; J. Waser 

Metal-Free Electrophilic Alkynylation of Sulfenate Anions with Ethynylbenziodoxolone Reagents

S. G. E. Amos; S. Nicolai; A. Gagnebin; F. Le Vaillant; J. Waser 

Palladium-Catalyzed Carbo-Oxygenation of Propargylic Amines using in Situ Tether Formation

P. D. G. Greenwood; E. Grenet; J. Waser 

Revisiting the Urech Synthesis of Hydantoins: Direct Access to Enantiopure 1,5-Substituted Hydantoins Using Cyanobenziodoxolone

N. Declas; F. Le Vaillant; J. Waser 

Cyclic Hypervalent Iodine Reagents for Azidation: Safer Reagents and Photoredox-Catalyzed Ring Expansion

S. Alazet; J. Preindl; R. Simonet-Davin; S. Nicolai; A. Nanchen et al. 

Fine-Tuned Organic Photoredox Catalysts for Fragmentation-Alkynylation Cascades of Cyclic Oxime Ethers

F. Le Vaillant; M. Garreau; S. Nicolai; G. Gryn’ova; C. Corminboeuf et al. 

Rhodium-catalyzed C–H functionalization of heteroarenes using indoleBX hypervalent iodine reagents

E. Grenet; A. K. Das; P. Caramenti; J. Waser 

Metal-Free Oxidative Cross Coupling of Indoles with Electron-Rich (Hetero)arenes

P. Caramenti; R. Nandi; J. Waser 

Iridium- and Rhodium-Catalyzed Directed C–H Heteroarylation of Benzaldehydes with Benziodoxolone Hypervalent Iodine Reagents

E. Grenet; J. Waser 

Lewis Acid Catalyzed Enantioselective Desymmetrization of Donor-Acceptor Meso-Diaminocyclopropanes

D. Perrotta; M. Wang; J. Waser 

Bench-Stable Electrophilic Indole and Pyrrole Reagents: Serendipitous Discovery and Use in C–H Functionalization

P. Caramenti 

Dearomatization of electron poor six-membered N-heterocycles through [3+2] annulation with aminocyclopropanes

J. Preindl; S. Chakrabarty; J. Waser 

Indole- and Pyrrole-BX: Bench-Stable Hypervalent Iodine Reagents for Heterocycle Umpolung

P. Caramenti; S. Nicolai; J. Waser 

Divergent Access to (1,1) and (1,2)-Azidolactones from Alkenes using Hypervalent Iodine Reagents

S. Alazet; F. Le Vaillant; S. Nicolai; T. Courant; J. Waser 

Room temperature decarboxylative cyanation of carboxylic acids using photoredox catalysis and cyanobenziodoxolones: a divergent mechanism compared to alkynylation

F. Le Vaillant; M. D. Wodrich; J. Waser 

Gold-catalyzed domino cyclization-alkynylation reactions with EBX reagents: new insights into the reaction mechanism

H. Ghari; Y. Li; R. Roohzadeh; P. Caramenti; J. Waser et al. 

Palladium-Catalyzed Carboamination of Allylic Alcohols Using a Trifluoroacetaldehyde-Derived Tether

B. Muriel; U. Orcel; J. Waser 

Heterotetracenes: Flexible Synthesis and in Silico Assessment of the Hole Transport Properties

Y. Li; G. Gryn’ova; F. Saenz; X. Jeanbourquin; K. Sivula et al. 

Enantioselective Copper-Catalyzed Oxy-Alkynylation of Diazo Compounds

D. P. Hari; J. Waser 

Decarboxylative Alkynylation and Cyanation of Carboxylic Acids using Photoredox Catalysis and Hypervalent Iodine Reagents

F. Le Vaillant; J. Waser 

Alkynylation of Thiols with Ethynylbenziodoxolone (EBX) Reagents: alpha- or beta- pi-Addition?

M. D. Wodrich; P. Caramenti; J. Waser 

Divergent Reactivity of Thioalkynes in Lewis Acid Catalyzed Annulations with Donor-Acceptor Cyclopropanes

S. Racine; B. Hegedus; R. Scopelliti; J. Waser 

Ethynyl benziodoxolones: functional terminators for cell-penetrating poly(disulfide)s

P. Morelli; X. Martin-Benlloch; R. Tessier; J. Waser; N. Sakai et al. 

Gold-catalyzed direct alkynylation of tryptophan in peptides using TIPS-EBX

G. L. Tolnai; J. P. Brand; J. Waser 

One-Pot Three-Component Synthesis of Vicinal Diamines via In Situ Aminal Formation and Carboamination

U. Orcel; J. Waser 

Nucleoside Analogues: Synthesis from Strained Rings

S. Racine; J. Vuilleumier; J. Waser 

Copper-Catalyzed Oxy-Alkynylation of Diazo Compounds with Hypervalent Iodine Reagents

D. P. Hari; J. Waser 

In the Lab Combining Catalyst and Reagent Design for Electrophilic Alkynylation Johnson Matthey Technology Review features new laboratory research

J. Waser 

Room-Temperature Decarboxylative Alkynylation of Carboxylic Acids Using Photoredox Catalysis and EBX Reagents

F. Le Vaillant; T. Courant; J. Waser 

Cyclic Hypervalent Iodine Reagents and Iron Catalysts: The Winning Team for Late-Stage C-H Azidation

M. V. Vita; J. Waser 

1-Alkynyltriazenes as Functional Analogues of Ynamides

F. G. Perrin; G. Kiefer; L. Jeanbourquin; S. Racine; D. Perrotta et al. 

Enantioselective Synthesis of Homoallylic Azides and Nitriles via Palladium-Catalyzed Decarboxylative Allylation

M. V. Vita; P. Caramenti; J. Waser 

General and Practical Formation of Thiocyanates from Thiols

R. Frei; T. Courant; M. D. Wodrich; J. Waser 

[4+2]-Annulations of Aminocyclobutanes

D. Perrotta; S. Racine; J. Vuilleumier; F. De Nanteuil; J. Waser 

Platinum-Catalyzed Domino Reactionwith Benziodoxole Reagents for Accessing Benzene-Alkynylated Indoles

Y. Li; J. Waser 

One-Pot, Three-Component Arylalkynyl Sulfone Synthesis

C. C. Chen; J. Waser 

Intramolecular palladium-catalyzed alkene carboalkynylation

S. Nicolai; P. Swallow; J. Waser 

Palladium-Catalyzed Vicinal Amino Alcohols Synthesis from Allyl Amines by In Situ Tether Formation and Carboetherification

U. Orcel; J. Waser 

Proteome-Wide Profiling of Targets of Cysteine reactive Small Molecules by Using Ethynyl Benziodoxolone Reagents

D. Abegg; R. Frei; L. Cerato; D. P. Hari; C. Wang et al. 

Room temperature alkynylation of H-phosphi(na)tes and secondary phosphine oxides with ethynylbenziodoxolone (EBX) reagents

C. C. Chen; J. Waser 

Synthesis of (Carbo) nucleoside Analogues by [3+2] Annulation of Aminocyclopropanes

S. Racine; F. De Nanteuil; E. Serrano; J. Waser 

Diester-Substituted Aminocyclopropanes: Synthesis and Use in [3+2]-Annulation Reactions

E. Serrano; F. De Nanteuil; J. Waser 

Dynamic Kinetic Asymmetric [3+2] Annulation Reactions of Aminocyclopropanes

F. De Nanteuil; E. Serrano; D. Perrotta; J. Waser 

Cyclization and annulation reactions of nitrogen-substituted cyclopropanes and cyclobutanes

F. De Nanteuil; F. De Simone; R. Frei; F. Benfatti; E. Serrano et al. 

Enantioselective Synthesis of Polycyclic Carbocycles via an Alkynylation-Allylation-Cyclization Strategy

M. V. Vita; P. Mieville; J. Waser 

Fast and Highly Chemoselective Alkynylation of Thiols with Hypervalent Iodine Reagents Enabled through a Low Energy Barrier Concerted Mechanism

R. Frei; M. D. Wodrich; D. P. Hari; P-A. Bonin; C. Chauvier et al. 

Total Synthesis and Biological Evaluation of Jerantinine E

R. Frei; D. Städler; A. Raja; R. Franke; F. Sasse et al. 

Synthesis of Aminocyclobutanes by Iron-Catalyzed [2+2] Cycloaddition

F. De Nanteuil; J. Waser 

Zinc-gold cooperative catalysis for the direct alkynylation of benzofurans

Y. Li; J. Waser 

Catalytic Friedel-Crafts Reaction of Aminocyclopropanes

F. De Nanteuil; J. Loup; J. Waser 

Gold-Catalyzed Regioselective Synthesis of 2- and 3-Alkynyl Furans

Y. Li; J. P. Brand; J. Waser 

A Highly Chemoselective and Practical Alkynylation of Thiols

R. Frei; J. Waser 

Ethynylbenziodoxolones (EBX) as Reagents for the Ethynylation of Stabilized Enolates

D. F. Gonzalez; J. P. Brand; R. Mondiere; J. Waser 

C2-Selective Direct Alkynylation of Indoles

G. L. Tolnai; S. Ganss; J. P. Brand; J. Waser 

Azidation of beta-Keto Esters and Silyl Enol Ethers with a Benziodoxole Reagent

M. V. Vita; J. Waser 

Pd(0)-Catalyzed Alkene Oxy- and Aminoalkynylation with Aliphatic Bromoacetylenes

S. Nicolai; R. Sedigh-Zadeh; J. Waser 

Iron-Catalyzed [3+2] Annulation of Aminocyclopropanes with Aldehydes: Stereoselective Synthesis of Aminotetrahydrofurans

F. Benfatti; F. de Nanteuil; J. Waser 

Para-Selective Gold-Catalyzed Direct Alkynylation of Anilines

J. P. Brand; J. Waser 

Ethynyl Benziodoxolones for the Direct Alkynylation of Heterocycles: Structural Requirement, Improved Procedure for Pyrroles, and Insights into the Mechanism

J. P. Brand; C. Chevalley; R. Scopelliti; J. Waser 

Synthesis of 1-[(Triisopropylsilyl)ethynyl]-1 lambda(3),2-benziodoxol-3(1H)-one and Alkynylation of Indoles, Thiophenes, and Anilines

J. P. Brand; J. Waser 

Catalytic Enantiospecific [3+2] Annulation of Aminocyclopropanes with Ketones

F. Benfatti; F. de Nanteuil; J. Waser 

Catalytic [3+2] Annulation of Aminocyclopropanes for the Enantiospecific Synthesis of Cyclopentylamines

F. de Nanteuil; J. Waser 

Benziodoxole-based hypervalent iodine reagents for atom-transfer reactions

J. P. Brand; D. Gonzalez Fernandez; S. Nicolai; J. Waser 

Cyclopropanes and Hypervalent Iodine Reagents: High Energy Compounds for Applications in Synthesis and Catalysis

D. Gonzalez Fernandez; F. De Simone; J. P. Brand; S. Nicolai; J. Waser 

Pd(0)-Catalyzed Oxy- and Aminoalkynylation of Olefins for the Synthesis of Tetrahydrofurans and Pyrrolidines

S. Nicolai; J. Waser 

One-pot gold-catalyzed synthesis of 3-silylethynyl indoles from unprotected o-alkynylanilines

J. P. Brand; C. Chevalley; J. Waser 

Formal Homo-Nazarov and Other Cyclization Reactions of Activated Cyclopropanes

F. De Simone; T. Saget; F. Benfatti; S. Almeida; J. Waser 

A Palladium-Catalyzed Aminoalkynylation Strategy towards Bicyclic Heterocycles: Synthesis of (±)-Trachelanthamidine

S. Nicolai; C. Piemontesi; J. Waser 

Synthesis of Chiral Bifunctional (Thio)Urea N-Heterocyclic Carbenes

J. P. Brand; J. I. Osuna-Siles; J. Waser 

Ethynyl-1,2-benziodoxol-3(1 H)-one (EBX): An Exceptional Reagent for the Ethynylation of Keto, Cyano, and Nitro Esters

D. Fernández González; J. P. Brand; J. Waser 

Pd-Catalyzed Intramolecular Oxyalkynylation of Alkenes with Hypervalent Iodine

S. Nicolai; S. Erard; D. Fernandez Gonzalez; J. Waser 

Catalytic Selective Cyclizations of Aminocyclopropanes: Formal Synthesis of Aspidospermidine and Total Synthesis of Goniomitine

F. De Simone; J. Gertsch; J. Waser 

Direct Alkynylation of Thiophenes: Cooperative Activation of TIPS–EBX with Gold and Brønsted Acids

J. P. Brand; J. Waser 

Catalytic Formal Homo-Nazarov Cyclization

F. De Simone; J. Andrès; R. Torosantucci; J. Waser 

Direct Alkynylation of Indole and Pyrrole Heterocycles

J. P. Brand; J. Charpentier; J. Waser 

Total Synthesis of (-)-Pseudolaric Acid B

B. M. Trost; J. Waser; A. Meyer 

Total synthesis of (-)-pseudolaric Acid B

B. M. Trost; J. Waser; A. Meyer 

Cobalt-Catalyzed Synthesis of Tertiary Azides from α,α-Disubstituted Olefins under Mild Conditions Using Commercially Available Reagents

B. Gaspar; J. Waser; E. M. Carreira 

Hydrazines and Azides via the Metal-Catalyzed Hydrohydrazination and Hydroazidation of Olefins

J. Waser; B. Gaspar; H. Nambu; E. M. Carreira 

Cobalt-Catalyzed Hydrohydrazination of Dienes and Enynes: Access to Allylic and Propargylic Hydrazides

J. Waser; J. C. Gonzalez-Gomez; H. Nambu; P. Huber; E. M. Carreira 

Cobalt-Catalyzed Hydroazidation of Olefins: Convenient Access to Alkyl Azides

J. Waser; H. Nambu; E. M. Carreira 

Alkene hydrazination: Catalytic hydrohydrazination of a wide range of alkenes with a simple Mn complex

J. Waser; E. M. Carreira 

Convenient synthesis of alkylhydrazides by the cobalt-catalyzed hydrohydrazination reaction of olefins and azodicarboxylates

J. Waser; E. M. Carreira 

Synthetic process development and scale up of palladium-catalyzed alkoxycarbonylation of chloropyridines

R. Crettaz; J. Waser; Y. Bessard 

The Azidofunctionalization of Alkenes

P. G. J. Palamini; J. Waser 

Photomediated aliphatic C-H functionalization

T. V. T. Nguyen; J. Waser 

Merging the Reactivity of (Pseudo)cyclic Hypervalent Iodine Reagents and Carbenes or Carbenoids

N. P. Ramirez; J. Waser 

X-Ray and NMR Structural Data of Ethynylbenziodoxolones (EBXs) Reagents and Their Analogues

E. Le Du; N. P. Ramirez; S. Nicolai; R. Scopelliti; F. Fadaei-Tirani et al. 

Recent progress in alkynylation with hypervalent iodine reagents

E. Le Du; J. Waser 

Azidation with Hypervalent Iodine Reagents

J. Waser; R. Simonet-Davin 

Pd-catalyzed functionalization of alkenes and alkynes using removable tethers

A. Das; J. Waser 

Activation of aminocyclopropanes via radical intermediates

M-M. Wang; T. V. T. Nguyen; J. Waser 

Radical Alkynylations with EthynylBenziodoXolones: From Photocatalysis to Direct Excitation

S. G. E. Amos; J. Waser 

Hypervalent Iodine-Mediated Late-Stage Peptide and Protein Functionalization

E. M. D. Allouche; E. Grinhagena; J. Waser 

Catalytic Enantioselective Ring-Opening Reactions of Cyclopropanes

V. Pirenne; B. Muriel; J. Waser 

Umpolung Of Electron-Rich Heteroarenes With Hypervalent Iodine Reagents

P. Pal; J. Waser; R. K. Nandi 

Palladium-Catalyzed Functionalization of Olefins and Alkynes: From Oxyalkynylation to Tethered Dynamic Kinetic Asymmetric Transformations (DYKAT)

S. Nicolai; U. Orcel; B. Muriel; P. D. G. Greenwood; L. Buzzetti et al. 

Vinylbenziodoxol(on)es: Synthetic Methods and Applications

N. Declas; G. Pisella; J. Waser 

Photocatalysis with organic dyes: facile access to reactive intermediates for synthesis

S. G. E. Amos; M. Garreau; L. Buzzetti; J. Waser 

Cyclic Hypervalent Iodine Reagents: Enabling Tools for Bond Disconnection via Reactivity Umpolung

D. P. Hari; P. Caramenti; J. Waser 

In situ tether formation from amines and alcohols enabling highly selective Tsuji-Trost allylation and olefin functionalization

U. Orcel; J. Waser 

Benziodoxol(on)e Reagents as Tools in Organic Synthesis: The Background behind the Discovery at the Laboratory of Catalysis and Organic Synthesis

J. Waser 

Cyclic Hypervalent Iodine Reagents for Atom-Transfer Reactions: Beyond Trifluoromethylation

Y. Li; D. P. Hari; M. V. Vita; J. Waser 

Taming Hypervalent Bonds and Strained Rings for Catalysis and Synthesis

F. De Nanteuil; Y. Li; M. V. Vita; R. Frei; E. Serrano et al. 

Gold-Catalyzed Alkynylation: Acetylene-Transfer instead of Functionalization

J. P. Brand; Y. Li; J. Waser 

Indole Alkaloids Synthesis via a Selective Cyclization of Aminocyclopropanes

F. De Simone; J. Waser 

Electrophilic alkynylation: the dark side of acetylene chemistry

J. P. Brand; J. Waser 

Asymmetric Organocatalysis Meets Hypervalent Iodine Chemistry for the alpha-Functionalization of Carbonyl Compounds

D. Gonzalez Fernandez; F. Benfatti; J. Waser 

Cyclization of Aminocyclopropanes in Indole Alkaloids Synthesis

F. De Simone; J. Waser 

Benziodoxole-based hypervalent iodine reagents for atom-transfer reactions

J. P. Brand; D. Fernandez Gonzalez; S. Nicolai; J. Waser 

Cyclization and Cycloaddition Reactions of Cyclopropyl Carbonyls and Imines

F. De Simone; J. Waser 

Cyclization of Cyclopropyl Carbonyls and the Homo-Nazarov Reaction

F. De Simone; J. Waser 

Development of synthetic methods starting from cyclopropenes: taming cyclopropyl radical, cyclopropyl and cyclopropenium cations

Synthesis and Activation of Heteroatom-Substituted Four-Membered Carbocycles

Photo-mediated generation of radical synthons from cyclopropanes

Radical-Mediated Azidation of Benzylic C-H Bonds and Azidofunctionalization of Alkenes

Integration of Hypervalent Iodine Reagents and Carbazolyl Cyanobenzenes-Based Dyes into Peptides: New Opportunities for Biomolecule Functionalization

Novel Alkynylation Methods through the Combination of Hypervalent Iodine Reagents and Alkynyl-trifluoroborate Salts

Photomediated Synthesis of Alkynylated Compounds from Readily Accessible Alcohols

Synthesis and application of bifunctional hypervalent iodine reagents for peptide modification.

Development of Hetero-Vinylbenziodoxolone Reagents for Applications in Synthetic Methodology and Biomolecule Functionalization

Hypervalent Iodine: New Reagents and Functionalization of Peptides

Chemodivergent Asymmetric Synthesis via Catalytically Formed Chiral Auxiliary

Azide-Containing Hypervalent Iodine Reagents for Biomolecules Functionalization

Ring-Opening Reactions of Aminocyclopropanes and Aminocyclobutanes

Rh-catalyzed C-H Bond Heteroarylation with Hypervalent Iodine Reagents and Pd-Catalyzed Tethered Functionalizations of Carbon-Carbon Multiple Bonds.

Photochemical Alkynylations with Hypervalent Iodine Reagents

New Strategies for the Functionalization of Alkenes Exploiting Tethering Chemistry and Ring Strain

New Vinylation and Alkynylation Strategies with Hypervalent Iodine Reagents and Diazo Compounds

Development of Photocatalysts towards the Visible-Light driven C-Terminal Bioconjugation of Peptides and Proteins

Palladium Catalysed Intramolecular Carbo-oxygenation of Propargylic Amines to Access 1,2-Amino Alcohols and alpha-Amino Ketones via in situ Tether Formation

Application of Hypervalent Iodine Reagents for Novel Cysteine Labeling

Photoredox-Catalyzed Decarboxylation for the Transfer of Alkynes and Nitriles Using Hypervalent Iodine Reagents

Development of New Strategies of Umpolung with Cyclic Hypervalent Iodine Reagents

Developing Reactions of Strained Rings : Enantioselective Desymmetrization of meso-Diaminocyclopropanes and Annulation of Donor-Acceptor Aminocyclobutanes

In Situ Tethering Strategies for the 3-Component Synthesis of Vicinal Amino Alcohols and Diamines via Pd-Catalyzed Carboetherification and Carboamination

Lewis acid Catalyzed Annulations of Donor-Acceptor Aminocyclopropanes and Aminocyclobutanes

Synthesis of Alkynylated Heterocycles by Direct C-H Alkynylation or Domino Alkynylation Reactions

Cyclic Hypervalent Iodine Reagents and Pd-Catalysis : Asymmetric Synthesis of α-Alkynyl and α-Azido Carbonyl Compounds

Synthesis and Reactivity of Donor-Acceptor Substituted Aminocyclopropanes and Aminocyclobutanes

Pd-Catalyzed Oxy- and Aminoalkynylation of Olefins

Development of Catalytic Umpolung : Part 1: Direct Alkynylation of Heterocycles and Electron-Rich Aromatics using Alkynyl-Benziodoxolones – Part 2: Synthesis of New Bifunctional (Thio)urea-Carbene Catalysts

Catalytic Formal Homo-Nazarov Reaction and Other Cyclizations of Cyclopropanes : from Methodology to Total Synthesis

New Acetylene Chemistry : Direct [alpha]-Alkynylation of Carbonyls with Ethynyl Benziodoxolones (EBX)

Donor-Acceptor Cyclopropanes with an Amino Group as Donor

1‐Azido‐3,3‐dimethyl‐3‐(1H )‐1,2‐benziodoxole

Silyl Ethynyl Benziodoxolone Reagents

Alkynylations and Vinylations

Alkynylation with Hypervalent Iodine Reagents

Synthesis of Saturated Heterocycles via Metal-Catalyzed Formal Cycloaddition Reactions That Generate a C–N or C–O Bond

Silyl Ethynyl Benziodoxolone Reagents

Azides by Olefin Hydroazidation Reactions

Accessing CF3-Cyclopropenes — A Platform for the Synthesis of Trifluoromethylated Building Blocks

W. Wu; T. M. Milzarek; M. D. Wodrich; J. Waser 

Peptide-Carbazolyl Cyanobenzene Conjugates: Enabling Biomolecule Functionalization via Photoredox and Energy Transfer Catalysis

X-Y. Lui; W. Cai; A-S. Chauvin; B. Fierz; J. Waser 

Raw data for article “Iron-catalyzed synthesis of α-azido α-amino esters via the alkylazidation of alkenes”

P. Palamini; E. Allouche; J. Waser