LCBM

Our main focus is to understand the molecular organization and function of chromatin, the DNA-protein complex which organizes the eukaryotic genome and regulates gene expression, using a combination of chemistry and biophysics.

Positions:

There are open positions for PhD students!

https://www.epfl.ch/schools/sb/research/isic/wp-content/uploads/2021/06/PhD_ad_2021_Fierz.pdf

If you are interested to perform a PhD thesis on the chemical biology and biophysics of chromatin or microtubules, directly contact: [email protected] 

If you are interested in a postdoctoral position, please contact: [email protected] 

Recent news:

August 2021:

LCBM welcomes Yana Berlina, a new PhD student. Welcome to Yuji Kamei, a new PhD student from LCBM and LSCO.

Kristina presented her work at the virtual CHSL Genome Engineering: CRISPR Frontiers conference. Congrats!

July 2021:

Alexandra and Kristina participated in the European Biophysics Conference (EBSA) in Vienna. Alexandra gave a short talk, and Kristina won a poster prize. Congratulations to both!

Recent publications:

New paper!

We present a modular fluorescence based in vitro workflow to directly observe dynamic interactions of effector proteins with defined chromatin fibres!

Check it out!

New review!

Find out about the higher order structure of the centromere!

Check it out!

New paper!

See the mechanism how the pioneer transcription factor Rap1 invades chromatin fibers!

Check it out!