Publications

For more information, visit our lab’s homepage at LBEM.ch 

2024

Computational drug development for membrane protein targets

H. Li; X. Sun; W. Cui; M. Xu; J. Dong et al. 

Nature Biotechnology. 2024. Vol. 42, num. 2, p. 229-242. DOI : 10.1038/s41587-023-01987-2.

2023

Structural basis of bile salt extrusion and small-molecule inhibition in human BSEP

H. Liu; R. N. Irobalieva; J. Kowal; D. Ni; K. Nosol et al. 

Nature Communications. 2023-11-10. Vol. 14, num. 1, p. 7296. DOI : 10.1038/s41467-023-43109-1.

Mechanical Properties and Nanomotion of BT-20 and ZR-75 Breast Cancer Cells Studied by Atomic Force Microscopy and Optical Nanomotion Detection Method

M. N. Starodubtseva; N. M. Shkliarava; I. A. Chelnokova; M. I. Villalba; A. Y. Krylov et al. 

Cells. 2023-10-01. Vol. 12, num. 19, p. 2362. DOI : 10.3390/cells12192362.

Structural Basis of the Allosteric Inhibition of Human ABCG2 by Nanobodies

R. N. Irobalieva; I. Manolaridis; S. M. Jackson; D. Ni; E. Pardon et al. 

Journal Of Molecular Biology. 2023-08-30. Vol. 435, num. 19, p. 168234. DOI : 10.1016/j.jmb.2023.168234.

Fully co-factor-free ClearTau platform produces seeding-competent Tau fibrils for reconstructing pathological Tau aggregates

G. Limorenko; M. Tatli; R. Kolla; S. Nazarov; M-T. Weil et al. 

Nature Communications. 2023-07-04. Vol. 14, num. 1, p. 3939. DOI : 10.1038/s41467-023-39314-7.

Activation mechanism of a short argonaute-TIR prokaryotic immune system

D. Ni; X. Lu; H. Stahlberg; B. Ekundayo 

Science Advances. 2023-07-01. Vol. 9, num. 29, p. eadh9002. DOI : 10.1126/sciadv.adh9002.

Genomic screening of 16 UK native bat species through conservationist networks uncovers coronaviruses with zoonotic potential

C. C. S. Tan; J. Trew; T. P. Peacock; K. Y. Mok; C. Hart et al. 

Nature Communications. 2023-06-27. Vol. 14, num. 1, p. 3322. DOI : 10.1038/s41467-023-38717-w.

On the Applications of the Generalized Littlewood Theorem Concerning Integrals of the Logarithm of Analytical Functions to Elliptic Functions

S. Sekatskii 

Axioms. 2023-06-01. Vol. 12, num. 6, p. 595. DOI : 10.3390/axioms12060595.

Secondary Structures of MERS-CoV, SARS-CoV, and SARS-CoV-2 Spike Proteins Revealed by Infrared Vibrational Spectroscopy

A. D’Arco; M. Di Fabrizio; T. Mancini; R. Mosetti; S. Macis et al. 

International Journal Of Molecular Sciences. 2023-05-31. Vol. 24, num. 11, p. 9550. DOI : 10.3390/ijms24119550.

De novo design of protein interactions with learned surface fingerprints

P. Gainza Cirauqui; S. Wehrle; A. K. Van Hall-Beauvais; A. Marchand; A. Scheck et al. 

Nature. 2023-04-26. Vol. 617, num. 7959, p. 176-184. DOI : 10.1038/s41586-023-05993-x.

Simple optical nanomotion method for single-bacterium viability and antibiotic response testing

M. I. Villalba; E. Rossetti; A. Bonvallat; C. Yvanoff; V. Radonicic et al. 

Proceedings Of The National Academy Of Sciences Of The United States Of America. 2023-04-25. Vol. 120, num. 18, p. e2221284120. DOI : 10.1073/pnas.2221284120.

Cryo-EM structures and binding of mouse and human ACE2 to SARS-CoV-2 variants of concern indicate that mutations enabling immune escape could expand host range

D. Ni; P. Turelli; B. Beckert; S. Nazarov; E. Uchikawa et al. 

PLOS Pathogens. 2023-04-05. Vol. 19, num. 4, p. e1011206. DOI : 10.1371/journal.ppat.1011206.

Single-Cell Optical Nanomotion of Candida albicans in Microwells for Rapid Antifungal Susceptibility Testing

V. Radonicic; C. Yvanoff; M. I. Villalba; B. Devreese; S. Kasas et al. 

Fermentation-Basel. 2023-04-01. Vol. 9, num. 4, p. 365. DOI : 10.3390/fermentation9040365.

Mitochondrial nanomotion measured by optical microscopy

P. Parmar; M. I. Villalba; A. S. H. Huber; A. Kalauzi; D. Bartolic et al. 

Frontiers In Microbiology. 2023-03-23. Vol. 14, p. 1133773. DOI : 10.3389/fmicb.2023.1133773.

Modulation of the nanoscale motion rate of Candida albicans by X-rays

M. N. Starodubtseva; I. A. Chelnokova; N. M. Shkliarava; M. I. Villalba; D. V. Tapalski et al. 

Frontiers In Microbiology. 2023-03-21. Vol. 14, p. 1133027. DOI : 10.3389/fmicb.2023.1133027.

Fast Self-Assembly Dynamics of a beta-Sheet Peptide Soft Material

J. Bertouille; S. Kasas; C. Martin; U. Hennecke; S. Ballet et al. 

Small. 2023-02-20. DOI : 10.1002/smll.202206795.

Structural and molecular determinants for the interaction of ExbB from Serratia marcescens and HasB, a TonB paralog (vol 5, 355, 2022)

V. Biou; R. J. D. Adaixo; M. Chami; P-D. Coureux; B. Laurent et al. 

Communications Biology. 2023-01-18. Vol. 6, num. 1, p. 67. DOI : 10.1038/s42003-022-04256-1.

Structure of a membrane-bound menaquinol:organohalide oxidoreductase

L. Cimmino; A. G. Duarte; D. Ni; B. E. Ekundayo; I. A. C. Pereira et al. 

Nature Communications. 2023. Vol. 14, p. 7038. DOI : 10.1038/s41467-023-42927-7.

Machine Learning in Protein Science De Novo Design of Site-Specific Protein Binders Using Surface Fingerprints

A. Van Hall-Beauvais; P. Gainza; S. Wehrle; A. Scheck; A. Marchand et al. 

2023-01-01. 36th Annual Symposium of the Protein-Society, San Francisco, CA, Jul 07-10, 2022.

On the Use of the Generalized Littlewood Theorem Concerning Integrals of the Logarithm of Analytical Functions for the Calculation of Infinite Sums and the Analysis of Zeroes of Analytical Functions

S. Sekatskii 

Axioms. 2023-01-01. Vol. 12, num. 1, p. 68. DOI : 10.3390/axioms12010068.

2022

Mechanism ofcyclic beta-glucan export by ABC transporter Cgt of Brucella

J. Sedzicki; D. Ni; F. Lehmann; N. Wu; R. Zenobi et al. 

Nature Structural & Molecular Biology. 2022-12-01. DOI : 10.1038/s41594-022-00868-7.

An Inertial Uni-Axial Interferometer-Based Accelerometer for Harsh Environments

G. A. Cervera; S. A. Solis Paiva; P. S. Galvez; J. S. Merino; M. Butcher et al. 

Ieee Sensors Journal. 2022-11-15. Vol. 22, num. 22, p. 21540-21549. DOI : 10.1109/JSEN.2022.3210369.

Allosteric control of type I-A CRISPR-Cas3 complexes and establishment as effective nucleic acid detection and human genome editing tools

C. Hu; D. Ni; K. H. Nam; S. Majumdar; J. McLean et al. 

Molecular Cell. 2022-08-04. Vol. 82, num. 15, p. 2754-+. DOI : 10.1016/j.molcel.2022.06.007.

Strontium Substituted Tricalcium Phosphate Bone Cement: Short and Long-Term Time-Resolved Studies and In Vitro Properties

J. Rau; I. Fadeeva; A. A. Forysenkova; G. A. Davydova; M. Fosca et al. 

Advanced Materials Interfaces. 2022-06-27.  p. 2200803. DOI : 10.1002/admi.202200803.

The Dynamics of Single-Cell Nanomotion Behaviour of Saccharomyces cerevisiae in a Microfluidic Chip for Rapid Antifungal Susceptibility Testing

V. Radonicic; C. Yvanoff; M. I. Villalba; S. Kasas; R. G. Willaert 

Fermentation-Basel. 2022-05-01. Vol. 8, num. 5, p. 195. DOI : 10.3390/fermentation8050195.

Structural and molecular determinants for the interaction of ExbB from Serratia marcescens and HasB, a TonB paralog

V. Biou; R. J. D. Adaixo; M. Chami; P-D. Coureux; B. Laurent et al. 

Communications Biology. 2022-04-13. Vol. 5, num. 355. DOI : 10.1038/s42003-022-03306-y.

Cryo-EM structures of a LptDE transporter in complex with Pro-macrobodies offer insight into lipopolysaccharide translocation

M. Botte; D. Ni; S. Schenck; I. Zimmermann; M. Chami et al. 

Nature Communications. 2022-04-05. Vol. 13, p. 1826. DOI : 10.1038/s41467-022-29459-2.

Trans‐seeding of Alzheimer‐related tau protein by a yeast prion

M. Flach; C. Leu; A. Martinisi; Z. Skachokova; S. Frank et al. 

Alzheimer’s & Dementia. 2022-02-09.  p. 1-12. DOI : 10.1002/alz.12581.

2.4-angstrom structure of the double-ring Gemmatimonas phototrophica photosystem

P. Qian; A. T. Gardiner; I. Simova; K. Naydenova; T. Croll et al. 

Science Advances. 2022-02-01. Vol. 8, num. 7, p. eabk3139. DOI : 10.1126/sciadv.abk3139.

Cryo-EM structure of native human thyroglobulin

R. Adaixo; E. M. Steiner; R. D. Righetto; A. Schmidt; H. Stahlberg et al. 

Nature Communications. 2022-01-10. Vol. 13, p. 61. DOI : 10.1038/s41467-021-27693-8.

2021

FTLD-TDP assemblies seed neoaggregates with subtype-specific features via a prion-like cascade

P. De Rossi; A. J. Lewis; J. Furrer; L. De Vos; T. Demeter et al. 

Embo Reports. 2021-11-22.  p. e53877. DOI : 10.15252/embr.202153877.

Structural strains of misfolded tau protein define different diseases

H. Stahlberg; R. Riek 

Nature. 2021-09-29. Vol. 598, num. 7880, p. 264-265. DOI : 10.1038/d41586-021-02611-6.

Nanomechanical bio-sensing for fast and reliable detection of viability and susceptibility of microorganisms

L. Venturelli; Z. R. Harrold; A. E. Murray; M. I. Villalba; E. M. Lundin et al. 

Sensors and Actuators B: Chemical. 2021-08-27. Vol. 348, p. 130650. DOI : 10.1016/j.snb.2021.130650.

Nanomotion Spectroscopy as a New Approach to Characterize Bacterial Virulence

M. Villalba; L. Venturelli; R. Willaert; M. E. Vela; O. Yantorno et al. 

Microorganisms. 2021-08-01. Vol. 9, num. 8, p. 1545. DOI : 10.3390/microorganisms9081545.

Structures of ABCG2 under turnover conditions reveal a key step in the drug transport mechanism

Q. Yu; D. Ni; J. Kowal; I. Manolaridis; S. M. Jackson et al. 

Nature Communications. 2021-07-19. Vol. 12, num. 1, p. 4376. DOI : 10.1038/s41467-021-24651-2.

Identification of a Dps contamination in Mitomycin-C–induced expression of Colicin Ia

J. Pipercevic; R. P. Jakob; R. D. Righetto; K. N. Goldie; H. Stahlberg et al. 

Biochimica et Biophysica Acta (BBA) – Biomembranes. 2021-07-16. Vol. 1863, num. 7, p. 183607. DOI : 10.1016/j.bbamem.2021.183607.

Structural basis of the activation of the CC chemokine receptor 5 by a chemokine agonist

P. Isaikina; C-J. Tsai; N. Dietz; F. Pamula; A. Grahl et al. 

Science Advances. 2021-06-01. Vol. 7, num. 25, p. eabg8685. DOI : 10.1126/sciadv.abg8685.

Structural basis of drug recognition by the multidrug transporter ABCG2

J. Kowal; D. Ni; S. M. Jackson; I. Manolaridis; H. Stahlberg et al. 

Journal of Molecular Biology. 2021-05-13. Vol. 433, num. 13, p. 166980. DOI : 10.1101/2021.02.18.431786.

Functional and structural characterization of Serratia marcescens ExbB: determinants of the interaction with HasB/TonB

V. Biou; R. J. Diogo Adaixo; M. Chami; P-D. Coureux; B. Laurent et al. 

bioRxiv. 2021-05-06. Vol. 2021.04.21.440815. DOI : 10.1101/2021.04.21.440815.

Nano-Motion Analysis for Rapid and Label Free Assessing of Cancer Cell Sensitivity to Chemotherapeutics

P. Stupar; A. Podolski-Renic; M. I. Villalba; M. Dragoj; S. Jovanovic Stojanov et al. 

Medicina-Lithuania. 2021-05-01. Vol. 57, num. 5, p. 446. DOI : 10.3390/medicina57050446.

Insight into Lipopolysaccharide Translocation by Cryo-EM structures of a LptDE Transporter in Complex with Pro-Macrobodies

M. Botte; D. Ni; S. Schenck; I. Zimmermann; M. Chami et al. 

bioRxiv. 2021-03-23. Vol. 2021.03.23.436624. DOI : 10.1101/2021.03.23.436624.

Nanophotonic structures with optical surface modes for tunable spin current generation

P. Shilina; D. O. Ignatyeva; P. O. Kapralov; S. K. Sekatskii; M. Nur-E-Alam et al. 

Nanoscale. 2021-03-21. Vol. 13, num. 11, p. 5791-5799. DOI : 10.1039/d0nr08692d.

Sensing of Surface and Bulk Refractive Index Using Magnetophotonic Crystal with Hybrid Magneto-Optical Response

D. Ignatyeva; P. Kapralov; P. Golovko; P. Shilina; A. Khramova et al. 

Sensors. 2021-03-11. Vol. 21, num. 6, p. 1984. DOI : 10.3390/s21061984.

Nanomotion Detection-Based Rapid Antibiotic Susceptibility Testing

S. Kasas; A. Malovichko; M. I. Villalba; M. E. Vela; O. Yantorno et al. 

Antibiotics. 2021-03-10. Vol. 10, num. 3, p. 287. DOI : 10.3390/antibiotics10030287.

Coordination-Driven Monolayer-to-Bilayer Transition in Two-Dimensional Metal–Organic Networks

M. Moradi; N. L. Lengweiler; C. E. Housecroft; L. G. Tulli; H. Stahlberg et al. 

The Journal of Physical Chemistry B. 2021-03-03. Vol. 125, num. 16, p. 4204-4211. DOI : 10.1021/acs.jpcb.1c01058.

Ultrasensitive Optical Label-Free Biosensing and Fluorescent Measurements using UV Surface Plasmons in Gold Nanolayers Launched with the Support of a Specially Designed Photonic Crystal

K. Prusakov; D. Basmanov; D. Klinov; S. K. Sekatskii 

2021-02-12.  p. 364A-364A. DOI : 10.1016/j.bpj.2020.11.2247.

Environmental Control of Amyloid Polymorphism by Modulation of Hydrodynamic Stress

J. Zhou; L. Venturelli; L. Keiser; S. K. Sekatskii; F. Gallaire et al. 

Acs Nano. 2021-01-26. Vol. 15, num. 1, p. 944-953. DOI : 10.1021/acsnano.0c07570.

Single Particle Analysis for High-Resolution 2D Electron Crystallography

R. Righetto; H. Stahlberg 

Methods in Molecular Biology. 2021-01-25. Vol. 2215, p. 267-284. DOI : 10.1007/978-1-0716-0966-8_12.

2020

Alterations in Sub-Axonal Architecture Between Normal Aging and Parkinson’s Diseased Human Brains Using Label-Free Cryogenic X-ray Nanotomography

H. T. Tran; E. H. R. Tsai; A. J. Lewis; T. Moors; J. G. J. M. Bol et al. 

Frontiers in Neuroscience. 2020-11-25. Vol. 14, p. 570019. DOI : 10.3389/fnins.2020.570019.

High-resolution cryo-EM structure of urease from the pathogen Yersinia enterocolitica

R. D. Righetto; L. Anton; R. Adaixo; R. P. Jakob; J. Zivanov et al. 

Nature Communications. 2020-11-01. Vol. 11, num. 1, p. 5101. DOI : 10.1038/s41467-020-18870-2.

Structural investigation of ACE2 dependent disassembly of the trimeric SARS-CoV-2 Spike glycoprotein

D. Ni; K. Lau; F. Lehmann; A. Fränkl; D. Hacker et al. 

bioRxiv. 2020-10-12.  p. 2020.10.12.336016. DOI : 10.1101/2020.10.12.336016.

Architecture of the centriole cartwheel‐containing region revealed by cryo‐electron tomography

N. Klena; M. Le Guennec; A. Tassin; H. van den Hoek; P. S. Erdmann et al. 

The EMBO Journal. 2020-09-22. Vol. 39, num. 22, p. 1-17, e106246. DOI : 10.15252/embj.2020106246.

Single particle cryo‐EM of the complex between interphotoreceptor retinoid‐binding protein and a monoclonal antibody

A. E. Sears; S. Albiez; S. Gulati; B. Wang; P. Kiser et al. 

The FASEB Journal. 2020-09-21. Vol. 34, num. 10, p. 13918-13934. DOI : 10.1096/fj.202000796RR.

Structural basis of Focal Adhesion Kinase activation on lipid membranes

I. Acebrón; R. D. Righetto; C. Schoenherr; S. Buhr; P. Redondo et al. 

The EMBO Journal. 2020-08-01. Vol. e104743, p. 1-21, e104743. DOI : 10.15252/embj.2020104743.

Protease-activation using anti-idiotypic masks enables tumor specificity of a folate receptor 1-T cell bispecific antibody

M. Geiger; K-G. Stubenrauch; J. Sam; W. F. Richter; G. Jordan et al. 

Nature Communications. 2020-06-24. Vol. 11, num. 1, p. 3169. DOI : 10.1038/s41467-020-16838-w.

The Contorsbody, an antibody format for agonism: design, structure, and function

G. J. Georges; S. Dengl; A. Bujotzek; F. Hesse; J. A. Fischer et al. 

Computational and Structural Biotechnology Journal. 2020-05-14. Vol. 18, p. 1210-1220. DOI : 10.1016/j.csbj.2020.05.007.

Cryo-EM, X-ray diffraction, and atomistic simulations reveal determinants for the formation of a supramolecular myelin-like proteolipid lattice

S. Ruskamo; O. C. Krokengen; J. Kowal; T. Nieminen; M. Lehtimaki et al. 

Journal of Biological Chemistry. 2020-04-07.  p. jbc.RA120.013087. DOI : 10.1074/jbc.RA120.013087.

New insights on the structure of alpha-synuclein fibrils using cryo-electron microscopy

R. Guerrero-Ferreira; L. Kovacik; D. Ni; H. Stahlberg 

Current Opinion in Neurobiology. 2020-04-01. Vol. 61, p. 89-95. DOI : 10.1016/j.conb.2020.01.014.

Grayscale e-beam lithography: Effects of a delayed development for well-controlled 3D patterning

T. Mortelmans; D. Kazazis; V. A. Guzenko; C. Padeste; T. Braun et al. 

Microelectronic Engineering. 2020-03-15. Vol. 225, p. 111272. DOI : 10.1016/j.mee.2020.111272.

A helical inner scaffold provides a structural basis for centriole cohesion

M. Le Guennec; N. Klena; D. Gambarotto; M. H. Laporte; A-M. Tassin et al. 

Science Advances. 2020-02-14. Vol. 6, num. 7, p. eaaz4137. DOI : 10.1126/sciadv.aaz4137.

2019

Two new polymorphic structures of human full-length alpha-synuclein fibrils solved by cryo-electron microscopy

R. Guerrero-Ferreira; N. M. Taylor; A-A. Arteni; P. Kumari; D. Mona et al. 

eLife. 2019-12-09. Vol. 8, p. e48907. DOI : 10.7554/eLife.48907.

Imaging of post-mortem human brain tissue using electron and X-ray microscopy

A. J. Lewis; C. Genoud; M. Pont; W. D. J. van de Berg; S. Frank et al. 

Current Opinion in Structural Biology. 2019-10-01. Vol. 58, p. 138-148. DOI : 10.1016/j.sbi.2019.06.003.

DuoMab: a novel CrossMab-based IgG-derived antibody format for enhanced antibody-dependent cell-mediated cytotoxicity

C. Sustmann; S. Dickopf; J. T. Regula; H. Kettenberger; M. Molhoj et al. 

mAbs. 2019-09-17. Vol. 11, num. 8, p. 1402-1414. DOI : 10.1080/19420862.2019.1661736.

Diverse roles of TssA-like proteins in the assembly of bacterial type VI secretion systems

J. P. Schneider; S. Nazarov; R. Adaixo; M. Liuzzo; P. D. Ringel et al. 

Embo Journal. 2019-08-12.  p. e100825. DOI : 10.15252/embj.2018100825.

Differential Visual Proteomics: Enabling the Proteome-Wide Comparison of Protein Structures of Single-Cells

A. Syntychaki; L. Rima; C. Schmidli; T. Stohler; A. Bieri et al. 

Journal of Proteome Research. 2019-07-29. Vol. 18, num. 9, p. 3521-3531. DOI : 10.1021/acs.jproteome.9b00447.

Microfluidic protein isolation and sample preparation for high-resolution cryo-EM

C. Schmidli; S. Albiez; L. Rima; R. Righetto; I. Mohammed et al. 

Proceedings of the National Academy of Sciences. 2019-07-10. Vol. 116, num. 30, p. 15007-15012. DOI : 10.1073/pnas.1907214116.

Cryo-EM structure of the rhodopsin-G alpha i-beta gamma complex reveals binding of the rhodopsin C-terminal tail to the g beta subunit

C-J. Tsai; J. Marino; R. Adaixo; F. Pamulal; J. Muehle et al. 

eLife. 2019-06-28. Vol. 8, p. e46041. DOI : 10.7554/eLife.46041.

Lewy pathology in Parkinson’s disease consists of crowded organelles and lipid membranes

S. H. Shahmoradian; A. J. Lewis; C. Genoud; J. Hench; T. E. Moors et al. 

Nature Neuroscience. 2019-06-24. Vol. 22, num. 7, p. 1099-1109. DOI : 10.1038/s41593-019-0423-2.

Tumor-targeted 4-1BB agonists for combination with T cell bispecific antibodies as off-the-shelf therapy

C. Claus; C. Ferrara; W. Xu; J. Sam; S. Lang et al. 

Science Translational Medicine. 2019-06-12. Vol. 11, num. 496, p. eaav5989. DOI : 10.1126/scitranslmed.aav5989.

Cryo-EM structures of the pore-forming A subunit from the Yersinia entomophaga ABC toxin

S. J. Piper; L. Brillault; R. Rothnagel; T. I. Croll; J. K. Box et al. 

Nature Communications. 2019-04-26. Vol. 10, num. 1, p. 1952. DOI : 10.1038/s41467-019-09890-8.

Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM

R. D. Righetto; N. Biyani; J. Kowal; M. Chami; H. Stahlberg 

Nature Communications. 2019-04-12. Vol. 10, num. 1, p. 1722. DOI : 10.1038/s41467-019-09661-5.

Supramolecular architectures of molecularly thin yet robust free-standing layers

M. Moradi; N. L. Opara; L. G. Tulli; C. Waeckerlin; S. J. Dalgarno et al. 

Science Advances. 2019-02-01. Vol. 5, num. 2, p. eaav4489. DOI : 10.1126/sciadv.aav4489.

Cryo-EM structure of phosphodiesterase 6 reveals insights into the allosteric regulation of type I phosphodiesterases

S. Gulati; K. Palczewski; A. Engel; H. Stahlberg; L. Kovacik 

Science Advances. 2019-02-01. Vol. 5, num. 2, p. eaav4322. DOI : 10.1126/sciadv.aav4322.

Molecular structure and function of myelin protein P0 in membrane stacking

A. Raasakka; S. Ruskamo; J. Kowal; H. Han; A. Baumann et al. 

Scientific Reports. 2019-01-24. Vol. 9, num. 1, p. 642. DOI : 10.1038/s41598-018-37009-4.

TDP-43 extracted from frontotemporal lobar degeneration subject brains displays distinct aggregate assemblies and neurotoxic effects reflecting disease progression rates

F. Laferriere; Z. Maniecka; M. Perez-Berlanga; M. Hruska-Plochan; L. Gilhespy et al. 

Nature Neuroscience. 2019. Vol. 22, num. 1, p. 65-77. DOI : 10.1038/s41593-018-0294-y.

2018

Cerebral Corpora amylacea are dense membranous labyrinths containing structurally preserved cell organelles

P. P. Navarro; C. Genoud; D. Castano-Diez; A. Graff-Meyer; A. J. Lewis et al. 

Scientific Reports. 2018-12-01. Vol. 8, num. 1, p. 18046. DOI : 10.1038/s41598-018-36223-4.

Self-Assembly of a Designed Nucleoprotein Architecture through Multimodal Interactions

R. H. Subramanian; S. J. Smith; R. G. Alberstein; J. B. Bailey; L. Zhang et al. 

ACS Central Science. 2018-11-15. Vol. 4, num. 11, p. 1578-1586. DOI : 10.1021/acscentsci.8b00745.

Cryo-EM structures of a human ABCG2 mutant trapped in ATP-bound and substrate-bound states

I. Manolaridis; S. M. Jackson; N. M. I. Taylor; J. Kowal; H. Stahlberg et al. 

Nature. 2018-11-07. Vol. 563, num. 7731, p. 426-430. DOI : 10.1038/s41586-018-0680-3.

Inner-membrane GspF of the bacterial type II secretion system is a dimeric adaptor mediating pseudopilus biogenesis

W. Van Putte; T. De Vos; W. Van Den Broeck; H. Stahlberg; M. Kudryashev et al. 

bioRxiv. 2018-10-05.  p. 435982. DOI : 10.1101/435982.

An iris diaphragm mechanism to gate a cyclic nucleotide-gated ion channel

A. Marchesi; X. Gao; R. Adaixo; J. Rheinberger; H. Stahlberg et al. 

Nature Communications. 2018-09-28. Vol. 9, num. 1, p. 3978. DOI : 10.1038/s41467-018-06414-8.

Structure of a PSI-LHCI-cyt b(6)f supercomplex in Chlamydomonas reinhardtii promoting cyclic electron flow under anaerobic conditions

J. Steinbeck; I. L. Ross; R. Rothnagel; P. Gaebelein; S. Schulze et al. 

Proceedings of the National Academy of Sciences. 2018-09-25. Vol. 115, num. 41, p. 10517-10522. DOI : 10.1073/pnas.1809973115.

Protocols for Subtomogram Averaging of Membrane Proteins in the Dynamo Software Package

P. P. Navarro; H. Stahlberg; D. Castano-Diez 

Frontiers in Molecular Biosciences. 2018-09-04. Vol. 5, p. 82. DOI : 10.3389/fmolb.2018.00082.

Demonstration of femtosecond X-ray pump X-ray probe diffraction on protein crystals

N. L. Opara; I. Mohacsi; M. Makita; D. Castano-Diez; A. Diaz et al. 

Structural Dynamics. 2018-09-01. Vol. 5, num. 5, p. 54303. DOI : 10.1063/1.5050618.

Miniaturized Sample Preparation for Transmission Electron Microscopy

C. Schmidli; L. Rima; S. A. Arnold; T. Stohler; A. Syntychaki et al. 

Journal of Visualized Experiments. 2018-07-27. num. 137, p. e57310. DOI : 10.3791/57310.

Cryo-EM structure of alpha-synuclein fibrils

R. Guerrero-Ferreira; N. M. I. Taylor; D. Mona; P. Ringler; M. E. Lauer et al. 

eLife. 2018-07-03. Vol. 7, p. e36402. DOI : 10.7554/eLife.36402.

Structural basis for regulation of human acetyl-CoA carboxylase

M. Hunkeler; A. Hagmann; E. Stuttfeld; M. Chami; Y. Guri et al. 

Nature. 2018-06-13. Vol. 558, num. 7710, p. 470-474. DOI : 10.1038/s41586-018-0201-4.

Femtosecond X-ray coherent diffraction of aligned amyloid fibrils on low background graphene

C. Seuring; K. Ayyer; E. Filippaki; M. Barthelmess; J-N. Longchamp et al. 

Nature Communications. 2018-05-09. Vol. 9, num. 1, p. 1836. DOI : 10.1038/s41467-018-04116-9.

Structural basis of small-molecule inhibition of human multidrug transporter ABCG2

S. M. Jackson; I. Manolaridis; J. Kowal; M. Zechner; N. M. I. Taylor et al. 

Nature Structural & Molecular Biology. 2018-04-01. Vol. 25, num. 4, p. 333-340. DOI : 10.1038/s41594-018-0049-1.

Image processing techniques for high-resolution structure determination from badly ordered 2D crystals

N. Biyani; S. Scherer; R. D. Righetto; J. Kowal; M. Chami et al. 

Journal of Structural Biology. 2018-04-01. Vol. 203, num. 2, p. 120-134. DOI : 10.1016/j.jsb.2018.03.013.

Miniaturizing EM Sample Preparation: Opportunities, Challenges, and “Visual Proteomics”

S. A. Arnold; S. A. Muller; C. Schmidli; A. Syntychaki; L. Rima et al. 

Proteomics. 2018-02-14. Vol. 18, num. 5-6, p. 1700176. DOI : 10.1002/pmic.201700176.

Structure of a zosuquidar and UIC2-bound human-mouse chimeric ABCB1

A. Alam; R. Kung; J. Kowal; R. A. McLeod; N. Tremp et al. 

Proceedings of the National Academy of Sciences. 2018-02-13. Vol. 115, num. 9, p. E1973-E1982. DOI : 10.1073/pnas.1717044115.

3D correlative electron microscopy reveals continuity of Brucella-containing vacuoles with the endoplasmic reticulum

J. Sedzicki; T. Tschon; S. H. Low; K. Willemart; K. N. Goldie et al. 

Journal of Cell Science. 2018-01-12. Vol. 131, num. 4, p. jcs210799. DOI : 10.1242/jcs.210799.

2017

Cryo-EM reconstruction of Type VI secretion system baseplate and sheath distal end

S. Nazarov; J. P. Schneider; M. Brackmann; K. N. Goldie; H. Stahlberg et al. 

The EMBO Journal. 2017-12-18. Vol. 37, num. 4, p. e97103. DOI : 10.15252/embj.201797103.

High-Resolution Cryoelectron Microscopy Structure of the Cyclic Nucleotide-Modulated Potassium Channel MloK1 in a Lipid Bilayer

J. Kowal; N. Biyani; M. Chami; S. Scherer; A. J. Rzepiela et al. 

Structure. 2017-12-01. Vol. 26, num. 1, p. 20. DOI : 10.1016/j.str.2017.11.012.

MRCZ – A file format for cryo-TEM data with fast compression

R. A. McLeod; R. D. Righetto; A. Stewart; H. Stahlberg 

Journal of Structural Biology. 2017-11-01. Vol. 201, num. 3, p. 252-257. DOI : 10.1016/j.jsb.2017.11.012.

Cryo-EM structure of the extended type VI secretion system sheath-tube complex

J. Wang; M. Brackmann; D. Castano-Diez; M. Kudryashev; K. N. Goldie et al. 

Nature Microbiology. 2017-09-25. Vol. 2, num. 11, p. 1507-1512. DOI : 10.1038/s41564-017-0020-7.

Cryo-EM analysis of homodimeric full-length LRRK2 and LRRK1 protein complexes

K. Sejwal; M. Chami; H. Remigy; R. Vancraenenbroeck; W. Sibran et al. 

Scientific Reports. 2017-08-17. Vol. 7, num. 1, p. 8667. DOI : 10.1038/s41598-017-09126-z.

Three-Dimensional Imaging of Biological Tissue by Cryo X-Ray Ptychography

S. H. Shahmoradian; E. H. R. Tsai; A. Diaz; M. Guizar-Sicairos; J. Raabe et al. 

Scientific Reports. 2017-07-24. Vol. 7, num. 1, p. 6291. DOI : 10.1038/s41598-017-05587-4.

Membrane Association Landscape of Myelin Basic Protein Portrays Formation of the Myelin Major Dense Line

A. Raasakka; S. Ruskamo; J. Kowal; R. Barker; A. Baumann et al. 

Scientific Reports. 2017-07-10. Vol. 7, num. 1, p. 4974. DOI : 10.1038/s41598-017-05364-3.

Lipid Internal Dynamics Probed in Nanodiscs

D. Martinez; M. Decossas; J. Kowal; L. Frey; H. Stahlberg et al. 

ChemPhysChem. 2017-06-30. Vol. 18, num. 19, p. 2651-2657. DOI : 10.1002/cphc.201700450.

Membrane vesicle secretion and prophage induction in multidrug-resistant Stenotrophomonas maltophilia in response to ciprofloxacin stress

S. Devos; W. Van Putte; J. Vitse; G. Van Driessche; S. Stremersch et al. 

Environmental Microbiology. 2017-06-22. Vol. 19, num. 10, p. 3930-3937. DOI : 10.1111/1462-2920.13793.

Direct protein crystallization on ultrathin membranes for diffraction measurements at X-ray free-electron lasers

N. Opara; I. Martiel; S. A. Arnold; T. Braun; H. Stahlberg et al. 

Journal of Applied Crystallography. 2017-06-01. Vol. 50, p. 909-918. DOI : 10.1107/S1600576717005799.

Structure of the human multidrug transporter ABCG2

N. M. I. .. Taylor; I. Manolaridis; S. M. Jackson; J. Kowal; H. Stahlberg et al. 

Nature. 2017-05-29. Vol. 546, num. 7659, p. 504-509. DOI : 10.1038/nature22345.

Focus: The interface between data collection and data processing in cryo-EM

N. Biyani; R. D. Righetto; R. McLeod; D. Caujolle-Bert; D. Castano-Diez et al. 

Journal of Structural Biology. 2017-05-01. Vol. 198, num. 2, p. 124-133. DOI : 10.1016/j.jsb.2017.03.007.

Robust image alignment for cryogenic transmission electron microscopy

R. A. McLeod; J. Kowal; P. Ringler; H. Stahlberg 

Journal of Structural Biology. 2017-03-01. Vol. 197, num. 3, p. 279-293. DOI : 10.1016/j.jsb.2016.12.006.

Blotting-free and lossless cryo-electron microscopy grid preparation from nanoliter-sized protein samples and single-cell extracts

S. A. Arnold; S. Albiez; A. Bieri; A. Syntychaki; R. Adaixo et al. 

Journal of Structural Biology. 2017-03-01. Vol. 197, num. 3, p. 220-226. DOI : 10.1016/j.jsb.2016.11.002.

Amyloid Fibril Polymorphism: Almost Identical on the Atomic Level, Mesoscopically Very Different

C. Seuring; J. Verasdonck; P. Ringler; R. Cadalbert; H. Stahlberg et al. 

The Journal of Physical Chemistry B. 2017-02-20. Vol. 121, num. 8, p. 1783-1792. DOI : 10.1021/acs.jpcb.6b10624.

Dynamo Catalogue: Geometrical tools and data management for particle picking in subtomogram averaging of cryo-electron tomograms

D. Castano-Diez; M. Kudryashev; H. Stahlberg 

Journal of Structural Biology. 2017-02-01. Vol. 197, num. 2, p. 135-144. DOI : 10.1016/j.jsb.2016.06.005.

Monitoring the Conformational Changes of Individual Cyclic Nucleotide-Gated Ion Channels by High-Speed Atomic Force Microscopy

M. Rangl; A. Miyagi; J. Kowal; H. Stahlberg; C. M. Nimigean et al. 

Biophysical Journal. 2017-02-01. Vol. 112, num. 3, p. 422A-422A. DOI : 10.1016/j.bpj.2016.11.2257.

Proteoliposomes – a system to study membrane proteins under buffer gradients by cryo-EM

K. Sejwal; M. Chami; P. Baumgartner; J. Kowal; S. A. Mueller et al. 

Nanotechnology Reviews. 2017-01-01. Vol. 6, num. 1, p. 57-74. DOI : 10.1515/ntrev-2016-0081.

Expression, Biochemistry, and Stabilization with Camel Antibodies of Membrane Proteins: Case Study of the Mouse 5-HT3 Receptor

G. Hassaïne; C. Deluz; L. Grasso; R. Wyss; R. Hovius et al. 

Membrane Protein Structure and Function Characterization; New York, NY: Springer New York, 2017. p. 139-168.

Cell-free reconstitution reveals centriole cartwheel assembly mechanisms

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Nature Communications. 2017. Vol. 8, p. 14813. DOI : 10.1038/ncomms14813.

Two-dimensional crystallization of the mouse serotonin 5-HT3A receptor

J. Rheinberger; G. Hassaine; M. Chami; H. Stahlberg; H. Vogel et al. 

Micron. 2017. Vol. 92, p. 19-24. DOI : 10.1016/j.micron.2016.10.004.

2016

Solution structure of discoidal high-density lipoprotein particles with a shortened apolipoprotein A-I

S. Bibow; Y. Polyhach; C. Eichmann; C. N. Chi; J. Kowal et al. 

Nature Structural & Molecular Biology. 2016-12-26. Vol. 24, num. 2, p. 187-193. DOI : 10.1038/nsmb.3345.

Real-time visualization of conformational changes within single MloK1 cyclic nucleotide-modulated channels

M. Rang; A. Miyagi; J. Kowal; H. Stahlberg; C. M. Nimigean et al. 

Nature Communications. 2016-09-20. Vol. 7, num. 1, p. 12789. DOI : 10.1038/ncomms12789.

Biochemical and biophysical approaches to study the structure and function of the chloride channel (ClC) family of proteins

P. D. Abeyrathne; M. Chami; H. Stahlberg 

Biochimie. 2016-09-01. Vol. 128, p. 154-162. DOI : 10.1016/j.biochi.2016.08.008.

Ultrathin membrane chips as X-ray transparent supports for serial crystallography

N. Opara; S. Arnold; T. Braun; H. Stahlberg; C. Padeste 

Acta Crystallographica Section A Foundations and Advances. 2016-08-28. Vol. 72, p. S184-S184. DOI : 10.1107/S2053273316097266.

GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death

L. Sborgi; S. Ruhl; E. Mulvihill; J. Pipercevic; R. Heilig et al. 

The EMBO Journal. 2016-07-14. Vol. 35, num. 16, p. 1766-1778. DOI : 10.15252/embj.201694696.

Total Sample Conditioning and Preparation of Nanoliter Volumes for Electron Microscopy

S. A. Arnold; S. Albiez; N. Opara; M. Chami; C. Schmidli et al. 

ACS Nano. 2016-05-24. Vol. 10, num. 5, p. 4981-4988. DOI : 10.1021/acsnano.6b01328.

Cholesteryl ester transfer between lipoproteins does not require a ternary tunnel complex with CETP

M. E. Lauer; A. Graff-Meyer; A. C. Rufer; C. Maugeais; E. von der Mark et al. 

Journal of Structural Biology. 2016-05-01. Vol. 194, num. 2, p. 191-198. DOI : 10.1016/j.jsb.2016.02.016.

Characterization of mAb dimers reveals predominant dimer forms common in therapeutic mAbs

F. Plath; P. Ringler; A. Graff-Meyer; H. Stahlberg; M. E. Lauer et al. 

mAbs. 2016-03-31. Vol. 8, num. 5, p. 928-940. DOI : 10.1080/19420862.2016.1168960.

Cullin-RING ubiquitin E3 ligase regulation by the COP9 signalosome

S. Cavadini; E. S. Fischer; R. D. Bunker; A. Potenza; G. M. Lingaraju et al. 

Nature. 2016-03-30. Vol. 531, num. 7596, p. 598-603. DOI : 10.1038/nature17416.

Preparation and Characterization of Stable -Synuclein Lipoprotein Particles

C. Eichmann; S. Campioni; J. Kowal; I. Maslennikov; J. Gerez et al. 

Journal of Biological Chemistry. 2016-02-04. Vol. 291, num. 16, p. 8516-8527. DOI : 10.1074/jbc.M115.707968.

Direct Visualization of Glutamate Transporter Transport Cycle

Y. Ruan; A. Miyagi; X. Wang; M. Chami; H. Stahlberg et al. 

Biophysical Journal. 2016-02-01. Vol. 110, num. 3, p. 178A-179A. DOI : 10.1016/j.bpj.2015.11.996.

The lipidome associated with the gamma-secretase complex is required for its integrity and activity

S. Ayciriex; H. Gerber; G. M. G. Osuna; M. Chami; H. Stahlberg et al. 

Biochemical Journal. 2016. Vol. 473, num. 3, p. 321-334. DOI : 10.1042/Bj20150448.

Structure of the T4 baseplate and its function in triggering sheath contraction

N. M. I. Taylor; N. S. Prokhorov; R. C. Guerrero-Ferreira; M. M. Shneider; C. Browning et al. 

Nature. 2016. Vol. 533, num. 7603, p. 346-352. DOI : 10.1038/nature17971.

The Structure of the Mouse Serotonin 5-HT3 Receptor in Lipid Vesicles

M. Kudryashev; D. Castaño-Díez; C. Deluz; G. Hassaine; L. Grasso et al. 

Structure. 2016. Vol. 24, num. 1, p. 165-170. DOI : 10.1016/j.str.2015.11.004.

2015

Structure and assembly of the mouse ASC inflammasome by combined NMR spectroscopy and cryo-electron microscopy

L. Sborgi; F. Ravotti; V. P. Dandey; M. S. Dick; A. Mazur et al. 

Proceedings of the National Academy of Sciences. 2015-10-13. Vol. 112, num. 43, p. 13237-13242. DOI : 10.1073/pnas.1507579112.

Translational arrest by a prokaryotic signal recognition particle is mediated by RNA interactions

B. Beckert; A. Kedrov; D. Sohmen; G. Kempf; K. Wild et al. 

Nature Structural & Molecular Biology. 2015-09-07. Vol. 22, num. 10, p. 767-773. DOI : 10.1038/nsmb.3086.

3D reconstruction of two-dimensional crystals

H. Stahlberg; N. Biyani; A. Engel 

Archives of Biochemistry and Biophysics. 2015-09-01. Vol. 581, p. 68-77. DOI : 10.1016/j.abb.2015.06.006.

CTF Challenge: Result summary

R. Marabini; B. Carragher; S. Chen; J. Chen; A. Cheng et al. 

Journal of Structural Biology. 2015-06-01. Vol. 190, num. 3, p. 348-359. DOI : 10.1016/j.jsb.2015.04.003.

Structure of the Type VI Secretion System Contractile Sheath

M. Kudryashev; R. Y-R. Wang; M. Brackmann; S. Scherer; T. Maier et al. 

Cell. 2015-02-01. Vol. 160, num. 5, p. 952-962. DOI : 10.1016/j.cell.2015.01.037.

Yersinia enterocolitica type III secretion injectisomes form regularly spaced clusters, which incorporate new machines upon activation

M. Kudryashev; A. Diepold; M. Amstutz; J. P. Armitage; H. Stahlberg et al. 

Molecular Microbiology. 2015-01-30. Vol. 95, num. 5, p. 875-884. DOI : 10.1111/mmi.12908.

2014

Disease Modeling and Phenotypic Drug Screening for Diabetic Cardiomyopathy using Human Induced Pluripotent Stem Cells

F. M. Drawnel; S. Boccardo; M. Prummer; F. Delobel; A. Graff et al. 

Cell Reports. 2014-11-01. Vol. 9, num. 3, p. 810-820. DOI : 10.1016/j.celrep.2014.09.055.

The ultrastructure of Chlorobaculum tepidum revealed by cryo-electron tomography

M. Kudryashev; A. Aktoudianaki; D. Dedoglou; H. Stahlberg; G. Tsiotis 

Biochimica et Biophysica Acta (BBA) – Bioenergetics. 2014-10-01. Vol. 1837, num. 10, p. 1635-1642. DOI : 10.1016/j.bbabio.2014.06.002.

Functional surface engineering by nucleotide-modulated potassium channel insertion into polymer membranes attached to solid supports

J. L. Kowal; J. K. Kowal; D. Wu; H. Stahlberg; C. G. Palivan et al. 

Biomaterials. 2014-08-01. Vol. 35, num. 26, p. 7286-7294. DOI : 10.1016/j.biomaterials.2014.05.043.

Structural and Mechanistic Paradigm of Leptin Receptor Activation Revealed by Complexes with Wild-Type and Antagonist Leptins

K. Moharana; L. Zabeau; F. Peelman; P. Ringler; H. Stahlberg et al. 

Structure. 2014-06-01. Vol. 22, num. 6, p. 866-877. DOI : 10.1016/j.str.2014.04.012.

Exploring the Interactome: Microfluidic Isolation of Proteins and Interacting Partners for Quantitative Analysis by Electron Microscopy

D. Giss; S. Kemmerling; V. Dandey; H. Stahlberg; T. Braun 

Analytical Chemistry. 2014-05-20. Vol. 86, num. 10, p. 4680-4687. DOI : 10.1021/ac4027803.

2dx_automator: Implementation of a semiautomatic high-throughput high-resolution cryo-electron crystallography pipeline

S. Scherer; J. Kowal; M. Chami; V. Dandey; M. Arheit et al. 

Journal of Structural Biology. 2014-05-01. Vol. 186, num. 2, p. 302-307. DOI : 10.1016/j.jsb.2014.03.016.

Relative bioavailability of a new tamper resistant extended-release oxycodone/naloxone combination product

H. Stahlberg; M. Brett; S. Schwier; A. Philipp 

The Journal of Pain. 2014-04-01. Vol. 15, num. 4, p. S86-S86. DOI : 10.1016/j.jpain.2014.01.354.

Rendering graphene supports hydrophilic with non-covalent aromatic functionalization for transmission electron microscopy

R. S. Pantelic; W. Fu; C. Schoenenberger; H. Stahlberg 

Applied Physics Letters. 2014-03-31. Vol. 104, num. 13, p. 134103. DOI : 10.1063/1.4870531.

Single particle 3D reconstruction for 2D crystal images of membrane proteins

S. Scherer; M. Arheit; J. Kowal; X. Zeng; H. Stahlberg 

Journal of Structural Biology. 2014-03-01. Vol. 185, num. 3, p. 267-277. DOI : 10.1016/j.jsb.2013.12.011.

A KcsA/MloK1 Chimeric Ion Channel Has Lipid-dependent Ligand-binding Energetics

J. G. McCoy; R. Rusinova; D. M. Kim; J. Kowal; S. Banerjee et al. 

Journal of Biological Chemistry. 2014-02-10. Vol. 289, num. 14, p. 9535-9546. DOI : 10.1074/jbc.M113.543389.

Ligand-induced structural changes in the cyclic nucleotide-modulated potassium channel MloK1

J. Kowal; M. Chami; P. Baumgartner; M. Arheit; P-L. Chiu et al. 

Nature Communications. 2014-01-28. Vol. 5, num. 1, p. 3106. DOI : 10.1038/ncomms4106.

Clostridium difficile toxin CDT hijacks microtubule organization and reroutes vesicle traffic to increase pathogen adherence

C. Schwan; A. S. Kruppke; T. Noelke; L. Schumacher; F. Koch-Nolte et al. 

Proceedings of the National Academy of Sciences. 2014-01-27. Vol. 111, num. 6, p. 2313-2318. DOI : 10.1073/pnas.1311589111.

Expression, Purification and Stabilization of the Mouse 5HT3 Receptor

G. Hassaine; C. Deluz; A. Graff; C. Moreau; R. Wyss et al. 

Biophysical Journal. 2014-01-01. Vol. 106, num. 2, p. 338A-338A. DOI : 10.1016/j.bpj.2013.11.1934.

X-ray structure of the mouse serotonin 5-HT3 receptor

G. Hassaine; C. Deluz; L. Grasso; R. Wyss; M. B. Tol et al. 

Nature. 2014. Vol. 512, p. 276-281. DOI : 10.1038/nature13552.

openBEB: open biological experiment browser for correlative measurements

C. Ramakrishnan; A. Bieri; N. Sauter; S. Roizard; P. Ringler et al. 

Bmc Bioinformatics. 2014. Vol. 15, p. 84. DOI : 10.1186/1471-2105-15-84.

2013

Cryo-electron microscopy of membrane proteins

K. N. Goldie; P. Abeyrathne; F. Kebbel; M. Chami; P. Ringler et al. 

Electron Microscopy; Humana Press, 2013-12-02. p. 325-41.

Structure of the Dodecameric Yersinia enterocolitica Secretin YscC and Its Trypsin-Resistant Core

J. Kowal; M. Chami; P. Ringler; S. A. Mueller; M. Kudryashev et al. 

Structure. 2013-12-01. Vol. 21, num. 12, p. 2152-2161. DOI : 10.1016/j.str.2013.09.012.

Growth of Large and Highly Ordered 2D Crystals of a K + Channel, Structural Role of Lipidic Environment (vol 105, pg 398, 2013)

R. De Zorzi; W. V. Nicholson; J. M. Guigner; F. Erne-Brand; H. Stahlberg et al. 

Biophysical Journal. 2013-09-01. Vol. 105, num. 5, p. 1285-1285. DOI : 10.1016/j.bpj.2013.08.005.

Single-cell lysis for visual analysis by electron microscopy

S. Kemmerling; S. A. Arnold; B. A. Bircher; N. Sauter; C. Escobedo et al. 

Journal of Structural Biology. 2013-09-01. Vol. 183, num. 3, p. 467-473. DOI : 10.1016/j.jsb.2013.06.012.

Vaccinia Virus Entry Is Followed by Core Activation and Proteasome-Mediated Release of the Immunomodulatory Effector VH1 from Lateral Bodies

F. I. Schmidt; C. K. E. Bleck; L. Reh; K. Novy; B. Wollscheid et al. 

Cell Reports. 2013-08-01. Vol. 4, num. 3, p. 464-476. DOI : 10.1016/j.celrep.2013.06.028.

Structure and Substrate-Induced Conformational Changes of the Secondary Citrate/Sodium Symporter CitS Revealed by Electron Crystallography

F. Kebbel; M. Kurz; M. Arheit; M. G. Gruetter; H. Stahlberg 

Structure. 2013-07-01. Vol. 21, num. 7, p. 1243-1250. DOI : 10.1016/j.str.2013.05.011.

Growth of Large and Highly Ordered 20 Crystals of a K+ Channel, Structural Role of Lipidic Environment

R. De Zorzi; W. V. Nicholson; J-M. Guigner; F. Erne-Brand; H. Stahlberg et al. 

Biophysical Journal. 2013-07-01. Vol. 105, num. 2, p. 398-408. DOI : 10.1016/j.bpj.2013.05.054.

Bridging from conventional marketed immediate release formulations to new tamper resistant alternatives

H. Stahlberg; M. Brett; J. Ossig; S. Schwier; A. Philipp 

The Journal of Pain. 2013-04-01. Vol. 14, num. 4, p. S70-S70. DOI : 10.1016/j.jpain.2013.01.617.

Image Processing of 2D Crystal Images

M. Arheit; D. Castaño-Díez; R. Thierry; B. R. Gipson; X. Zeng et al. 

Electron Crystallography of Soluble and Membrane Proteins; 2013. p. 171-194.

Cryo-electron tomography reveals four-membrane architecture of the Plasmodium apicoplast

L. Lemgruber; M. Kudryashev; C. Dekiwadia; D. T. Riglar; J. Baum et al. 

Malaria Journal. 2013-01-01. Vol. 12, num. 1, p. 25. DOI : 10.1186/1475-2875-12-25.

In situ structural analysis of the Yersinia enterocolitica injectisome

M. Kudryashev; M. Stenta; S. Schmelz; M. Amstutz; U. Wiesand et al. 

Elife. 2013. Vol. 2, p. e00792. DOI : 10.7554/eLife.00792.

Molecular assembly of the aerolysin pore reveals a swirling membrane-insertion mechanism

M. T. Degiacomi; I. Lacovache; L. Pernot; M. Chami; M. Kudryashev et al. 

Nature Chemical Biology. 2013. Vol. 9, num. 10, p. 623-629. DOI : 10.1038/Nchembio.1312.

Thermal Unfolding of a Mammalian Pentameric Ligand-gated Ion Channel Proceeds at Consecutive, Distinct Steps

M. B. Tol; C. Deluz; G. Hassaine; A. Graff; H. Stahlberg et al. 

Journal of Biological Chemistry. 2013. Vol. 288, p. 5756-5769. DOI : 10.1074/jbc.M112.422287.

2012

Automation of image processing in electron crystallography

M. Arheit; D. Castano-Diez; R. Thierry; B. R. Gipson; X. Zeng et al. 

Electron Crystallography of Soluble and Membrane Proteins; Humana Press, 2012-10-07. p. 313-30.

Merging of image data in electron crystallography

M. Arheit; D. Castano-Diez; R. Thierry; P. Abeyrathne; B. R. Gipson et al. 

Electron Crystallography of Soluble and Membrane Proteins; Humana Press, 2012-10-07. p. 195-209.

RNAi Screening Reveals Proteasome- and Cullin3-Dependent Stages in Vaccinia Virus Infection

J. Mercer; B. Snijder; R. Sacher; C. Burkard; C. K. E. Bleck et al. 

Cell Reports. 2012-10-01. Vol. 2, num. 4, p. 1036-1047. DOI : 10.1016/j.celrep.2012.09.003.

The application of graphene as a sample support in transmission electron microscopy

R. S. Pantelic; J. C. Meyer; U. Kaiser; H. Stahlberg 

Solid State Communications. 2012-08-01. Vol. 152, num. 15, p. 1375-1382. DOI : 10.1016/j.ssc.2012.04.038.

Structural basis for chirality and directional motility of Plasmodium sporozoites

M. Kudryashev; S. Muenter; L. Lemgruber; G. Montagna; H. Stahlberg et al. 

Cellular Microbiology. 2012-07-30. Vol. 14, num. 11, p. 1757-1768. DOI : 10.1111/j.1462-5822.2012.01836.x.

Characterization of the motion of membrane proteins using high-speed atomic force microscopy

I. Casuso; J. Khao; M. Chami; P. Paul-Gilloteaux; M. Husain et al. 

Nature Nanotechnology. 2012-07-08. Vol. 7, num. 8, p. 525-529. DOI : 10.1038/NNANO.2012.109.

Limiting factors in single particle cryo electron tomography

M. Kudryashev; D. Castano-Diez; H. Stahlberg 

Computational and Structural Biotechnology Journal. 2012-07-01. Vol. 1, num. 2, p. e201207002. DOI : 10.5936/csbj.201207002.

Mus81-Mms4 Functions as a Single Heterodimer To Cleave Nicked Intermediates in Recombinational DNA Repair

E. K. Schwartz; W. D. Wright; K. T. Ehmsen; J. E. Evans; H. Stahlberg et al. 

Molecular and Cellular Biology. 2012-05-29. Vol. 32, num. 15, p. 3065-3080. DOI : 10.1128/MCB.00547-12.

Dynamo: A flexible, user-friendly development tool for subtomogram averaging of cryo-EM data in high-performance computing environments

D. Castano-Diez; M. Kudryashev; M. Arheit; H. Stahlberg 

Journal of Structural Biology. 2012-05-01. Vol. 178, num. 2, p. 139-151. DOI : 10.1016/j.jsb.2011.12.017.

Assessing the benefits of focal pair cryo-electron tomography

M. Kudryashev; H. Stahlberg; D. Castano-Diez 

Journal of Structural Biology. 2012-05-01. Vol. 178, num. 2, p. 88-97. DOI : 10.1016/j.jsb.2011.10.004.

Structure and Function of Purified Monoclonal Antibody Dimers Induced by Different Stress Conditions

R. Paul; A. Graff-Meyer; H. Stahlberg; M. E. Lauer; A. C. Rufer et al. 

Pharmaceutical Research. 2012-04-05. Vol. 29, num. 8, p. 2047-2059. DOI : 10.1007/s11095-012-0732-6.

Projection Structure of the Secondary Citrate/Sodium Symporter CitS at 6 angstrom Resolution by Electron Crystallography

F. Kebbel; M. Kurz; M. G. Gruetter; H. Stahlberg 

Journal of Molecular Biology. 2012-04-01. Vol. 418, num. 01.févr., p. 117-126. DOI : 10.1016/j.jmb.2012.02.016.

Iterative Transform Algorithms for 3D Reconstruction of 2D Crystals

X. Z. –; Y. C. –; O. H. –; H. Stahlberg 

Journal of Next Generation Information Technology. 2012-02-29. Vol. 3, num. 1, p. 28-35. DOI : 10.4156/jnit.vol3.issue1.4.

Connecting mu-fluidics to electron microscopy

S. Kemmerling; J. Ziegler; G. Schweighauser; S. A. Arnold; D. Giss et al. 

Journal of Structural Biology. 2012-01-01. Vol. 177, num. 1, p. 128-134. DOI : 10.1016/j.jsb.2011.11.001.

Ionic liquids as matrices in microfluidic sample deposition for high-mass matrix-assisted laser desorption/ionization mass spectrometry

S. Weidmann; S. Kemmerling; S. Maedler; H. Stahlberg; T. Braun et al. 

European Journal of Mass Spectrometry. 2012-01-01. Vol. 18, num. 3, p. 279-286. DOI : 10.1255/ejms.1182.

Complete Lateral and Angular Diffusion and Protein-Protein Interaction Description of a Membrane Protein

I. Casuso; J-P. Duneau; M. Chami; P. Paul-Gilloteaux; M. Husain et al. 

Biophysical Journal. 2012-01-01. Vol. 102, num. 3, p. 413A-414A. DOI : 10.1016/j.bpj.2011.11.2261.

Interactions of CCR5, the Main HIV Coreceptor, with Rantes and Other Ligands

S. Morin; L. Nisius; M. Wiktor; F. Kebbel; H. Stahlberg et al. 

Biophysical Journal. 2012-01-01. Vol. 102, num. 3, p. 239A-240A. DOI : 10.1016/j.bpj.2011.11.1319.

2011

Rad51 paralogues Rad55-Rad57 balance the antirecombinase Srs2 in Rad51 filament formation

J. Liu; L. Renault; X. Veaute; F. Fabre; H. Stahlberg et al. 

Nature. 2011-10-23. Vol. 479, num. 7372, p. 245-U129. DOI : 10.1038/nature10522.

Oxidative Doping Renders Graphene Hydrophilic, Facilitating Its Use As a Support in Biological TEM

R. S. Pantelic; J. W. Suk; Y. Hao; R. S. Ruoff; H. Stahlberg 

Nano Letters. 2011-10-12. Vol. 11, num. 10, p. 4319-4323. DOI : 10.1021/nl202386p.

Interaction of complexes I, III, and IV within the bovine respirasome by single particle cryoelectron tomography

N. V. Dudkina; M. Kudryashev; H. Stahlberg; E. J. Boekema 

Proceedings of the National Academy of Sciences. 2011-08-29. Vol. 108, num. 37, p. 15196-15200. DOI : 10.1073/pnas.1107819108.

Automatic recovery of missing amplitudes and phases in tilt-limited electron crystallography of two-dimensional crystals

B. R. Gipson; D. J. Masiel; N. D. Browning; J. Spence; K. Mitsuoka et al. 

Physical Review E. 2011-07-22. Vol. 84, num. 1, p. 11916. DOI : 10.1103/PhysRevE.84.011916.

Polymer-based cell-free expression of ligand-binding family B G-protein coupled receptors without detergents

C. Klammt; M. H. Perrin; I. Maslennikov; L. Renault; M. Krupa et al. 

Protein Science. 2011-05-03. Vol. 20, num. 6, p. 1030-1041. DOI : 10.1002/pro.636.

Graphene: Substrate preparation and introduction

R. S. Pantelic; J. W. Suk; C. W. Magnuson; J. C. Meyer; P. Wachsmuth et al. 

Journal of Structural Biology. 2011-04-01. Vol. 174, num. 1, p. 234-238. DOI : 10.1016/j.jsb.2010.10.002.

3D Reconstruction of 2D Crystals

X. Zeng; J. E. Glover; O. Hughes; H. Stahlberg 

2011-01-01. 49th Annual Association-for-Computing-Machinery (ACM) Southeast Conference (ACMSE)49th Annual Association-for-Computing-Machinery (ACM) Southeast Conference (ACMSE). p. 160-165. DOI : 10.1145/2016039.2016084.

2010

Filling the missing cone: Automatic recovery of data in tilt-limited microscopy

H. Stahlberg; X. Zeng; D. J. Masiel; N. Browning; J. Spence et al. 

Acta Crystallographica Section A Foundations of Crystallography. 2010-08-29. Vol. 66, p. S17-S17. DOI : 10.1107/S0108767310099642.

An optical and microPET assessment of thermally-sensitive liposome biodistribution in the Met-1 tumor model: Importance of formulation

E. E. Paoli; D. E. Kruse; J. W. Seo; H. Zhang; A. Kheirolomoom et al. 

Journal of Controlled Release. 2010-04-02. Vol. 143, num. 1, p. 13-22. DOI : 10.1016/j.jconrel.2009.12.010.

Preparation of 2D Crystals of Membrane Proteins for High-Resolution Electron Crystallography Data Collection

P. D. Abeyrathne; M. Chami; R. S. Pantelic; K. N. Goldie; H. Stahlberg 

Cryo-EM Part A Sample Preparation and Data Collection; Elsevier, 2010-01-01. p. 25-43.

3D Reconstruction from 2D Crystal Image and Diffraction Data

A. D. Schenk; D. Castano-Diez; B. Gipson; M. Arheit; X. Zeng et al. 

Cryo-EM, Part B: 3-D Reconstruction; Elsevier, 2010-01-01. p. 101-129.

2009

High-resolution low-dose scanning transmission electron microscopy

J. P. Buban; Q. Ramasse; B. Gipson; N. D. Browning; H. Stahlberg 

Journal of Electron Microscopy. 2009-11-14. Vol. 59, num. 2, p. 103-112. DOI : 10.1093/jmicro/dfp052.

Coassembly of Mgm1 isoforms requires cardiolipin and mediates mitochondrial inner membrane fusion

R. M. DeVay; L. Dominguez-Ramirez; L. L. Lackner; S. Hoppins; H. Stahlberg et al. 

The Journal of Cell Biology. 2009-09-14. Vol. 186, num. 6, p. 793-803. DOI : 10.1083/jcb.200906098.

Structural variability of edge dislocations in a SrTiO(3) low-angle [001] tilt grain boundary

J. P. Buban; M. Chi; D. J. Masiel; J. P. Bradley; B. Jiang et al. 

Journal of Materials Research. 2009-07-01. Vol. 24, num. 7, p. 2191-2199. DOI : 10.1557/JMR.2009.0259.

Crystal Structures of Limulus SAP-Like Pentraxin Reveal Two Molecular Aggregations

A. K. Shrive; I. Burns; H-T. Chou; H. Stahlberg; P. B. Armstrong et al. 

Journal of Molecular Biology. 2009-03-01. Vol. 386, num. 5, p. 1240-1254. DOI : 10.1016/j.jmb.2009.01.008.

Membrane activity of a C-reactive protein

J. M. Harrington; H-T. Chou; T. Gutsmann; C. Gelhaus; H. Stahlberg et al. 

FEBS Letters. 2009-02-20. Vol. 583, num. 6, p. 1001-1005. DOI : 10.1016/j.febslet.2009.02.019.

2007 annual progress report synopsis of the Center for Structures of Membrane Proteins

R. M. Stroud; S. Choe; J. Holton; H. R. Kaback; W. Kwiatkowski et al. 

Journal of Structural and Functional Genomics. 2009-01-16. Vol. 10, num. 2, p. 193-208. DOI : 10.1007/s10969-008-9058-3.

2008

Low-dose aberration corrected cryo-electron microscopy of organic specimens

J. E. Evans; C. Hetherington; A. Kirkland; L-Y. Chang; H. Stahlberg et al. 

Ultramicroscopy. 2008-11-01. Vol. 108, num. 12, p. 1636-1644. DOI : 10.1016/j.ultramic.2008.06.004.

Bridging across length scales: Multi-scale ordering of supported lipid bilayers via lipoprotein self-assembly and surface patterning

M. S. Vinchurkar; D. A. Bricarello; J. O. Lagerstedt; J. P. Buban; H. Stahlberg et al. 

Journal of the American Chemical Society. 2008-08-01. Vol. 130, num. 33, p. 11164-11169. DOI : 10.1021/ja803110v.

2dx – Automated 3D structure reconstruction from 2D crystal data

B. Gipson; X. Zeng; H. Stahlberg 

Microscopy and Microanalysis. 2008-08-01. Vol. 14, num. S2, p. 1290-1291. DOI : 10.1017/S1431927608081919.

Membrane pore formation by pentraxin proteins from Limulus, the American horseshoe crab

J. M. Harrington; H-T. Chou; T. Gutsmann; C. Gelhaus; H. Stahlberg et al. 

Biochemical Journal. 2008-07-15. Vol. 413, num. 2, p. 305-313. DOI : 10.1042/BJ20071357.

The fold of alpha-synuclein fibrils

M. Vilar; H-T. Chou; T. Luehrs; S. K. Maji; D. Riek-Loher et al. 

Proceedings of the National Academy of Sciences. 2008-06-12. Vol. 105, num. 25, p. 8637-8642. DOI : 10.1073/pnas.0712179105.

Molecular electron microscopy: State of the art and current challenges

H. Stahlberg; T. Walz 

ACS Chemical Biology. 2008-05-01. Vol. 3, num. 5, p. 268-281. DOI : 10.1021/cb800037d.

2007

Automatic lattice determination for two-dimensional crystal images

X. Zeng; B. Gipson; Z. Y. Zheng; L. Renault; H. Stahlberg 

Journal of Structural Biology. 2007-12-01. Vol. 160, num. 3, p. 353-361. DOI : 10.1016/j.jsb.2007.08.008.

2dx_merge: Data management and merging for 2D crystal images

B. Gipson; X. Zeng; H. Stahlberg 

Journal of Structural Biology. 2007-12-01. Vol. 160, num. 3, p. 375-384. DOI : 10.1016/j.jsb.2007.09.011.

Electron crystallography of membrane proteins

B. Hankamer; R. Glaeser; H. Stahlberg 

Journal of Structural Biology. 2007-12-01. Vol. 160, num. 3, p. 263-264. DOI : 10.1016/j.jsb.2007.11.001.

A maximum likelihood approach to two-dimensional crystals

X. Zeng; H. Stahlberg; N. Grigorieff 

Journal of Structural Biology. 2007-12-01. Vol. 160, num. 3, p. 362-374. DOI : 10.1016/j.jsb.2007.09.013.

2dx – User Friendly Image Processing (and Merging) for 2D Crystals

B. Gipson; Zeng; H. Stahlberg; R. Wouts 

Microscopy and Microanalysis. 2007-09-01. Vol. 13, num. S03, p. 160–161. DOI : 10.1017/S1431927607080804.

The structure of the prokaryotic cyclic nucleotide-modulated potassium channel MIoK1 at 16 angstrom resolution

P-L. Chiu; M. D. Pagel; J. Evans; H-T. Chou; X. Zeng et al. 

Structure. 2007-09-01. Vol. 15, num. 9, p. 1053-1064. DOI : 10.1016/j.str.2007.06.020.

Oocyte CD9 is enriched on the microvillar membrane and required for normal microvillar shape and distribution

K. E. Runge; J. E. Evans; Z-Y. He; S. Gupta; K. L. McDonald et al. 

Developmental Biology. 2007-04-01. Vol. 304, num. 1, p. 317-325. DOI : 10.1016/j.ydbio.2006.12.041.

Structural and kinetic studies of induced fit in xylulose kinase from Escherichia coli

E. Di Luccio; B. Petschacher; J. Voegtli; H-T. Chou; H. Stahlberg et al. 

Journal of Molecular Biology. 2007-01-01. Vol. 365, num. 3, p. 783-798. DOI : 10.1016/j.jmb.2006.10.068.

2dx – User-friendly image processing for 2D crystals

B. Gipson; X. Zeng; Z. Y. Zhang; H. Stahlberg 

Journal of Structural Biology. 2007-01-01. Vol. 157, num. 1, p. 64-72. DOI : 10.1016/j.jsb.2006.07.020.

Electron Crystallography of Membrane Proteins

H-T. Chou; J. E. Evans; H. Stahlberg 

Electron Microscopy; 2007. p. 331-343.

2006

Correction: Functional modulation of IFT kinesins extends the sensory repertoire of ciliated neurons in Caenorhabditis elegans

J. E. Evans; J. J. Snow; A. L. Gunnarson; G. Ou; H. Stahlberg et al. 

The Journal of Cell Biology. 2006-12-04. Vol. 175, num. 5, p. 837-837. DOI : 10.1083/jcb.200509115520061120c.

A homotetrameric kinesin-5, KLP61F, bundles microtubules and antagonizes Ncd in motility assays

L. Tao; A. Mogilner; G. Civelekogiu-Scholey; R. Wollman; J. Evans et al. 

Current Biology. 2006-12-01. Vol. 16, num. 23, p. 2293-2302. DOI : 10.1016/j.cub.2006.09.064.

Milestones in electron crystallography

L. Renault; H-T. Chou; P-L. Chiu; R. M. Hill; X. Zeng et al. 

Journal of Computer-Aided Molecular Design. 2006-11-11. Vol. 20, num. 07.août, p. 519-527. DOI : 10.1007/s10822-006-9075-x.

Applications of Atomic Scale Scanning Transmission Electron Microscopy

N. Browning; R. Erni; C. Mitterbauer; L. Fu; M. Chi et al. 

Microscopy and Microanalysis. 2006-07-31. Vol. 12, num. S02, p. 134-135. DOI : 10.1017/S143192760606627X.

Cryo-Electron Microscopy Analysis of a 105 kDa Protein Particle: The Xylulose Kinase from E. Coli

Chou; E. d. Luccio; D. Wilson; H. Stahlberg 

Microscopy and Microanalysis. 2006-07-31. Vol. 12, num. S02, p. 408-409. DOI : 10.1017/S1431927606066530.

Avoiding Charge Induced Drift In Vitrified Biological Specimens Through Scanning Transmission Electron Microscopy

G. Nicotra; Chou; H. Stahlberg; N. Browning 

Microscopy and Microanalysis. 2006-07-31. Vol. 12, num. S02, p. 246-247. DOI : 10.1017/S1431927606063070.

Double hexameric ring assembly of the type III protein translocase ATPase HrcN

S. A. Mueller; C. Pozidis; R. Stone; C. Meesters; M. Chami et al. 

Molecular Microbiology. 2006-06-01. Vol. 61, num. 1, p. 119-125. DOI : 10.1111/j.1365-2958.2006.05219.x.

Functional modulation of IFT kinesins extends the sensory repertoire of ciliated neurons in Caenorhabditis elegans (vol 172, pg 663, 2006)

J. E. Evans; J. J. Snow; A. L. Gunnarson; G. Ou; H. Stahlberg et al. 

The Journal of Cell Biology. 2006-03-06. Vol. 172, num. 6, p. 949-949. DOI : 10.1083/jcb.20050911520060224c.

Functional modulation of IFT kinesins extends the sensory repertoire of ciliated neurons in Caenorhabditis elegans

J. Evans; J. Snow; A. Gunnarson; G. Ou; H. Stahlberg et al. 

The Journal of Cell Biology. 2006-02-21. Vol. 172, num. 5, p. 663-669. DOI : 10.1083/jcb.200509115.

2005

The 4.5 angstrom structure of human AQP2

A. Schenk; P. Werten; S. Scheuring; B. de Groot; S. Muller et al. 

Journal of Molecular Biology. 2005-07-01. Vol. 350, num. 2, p. 278-289. DOI : 10.1016/j.jmb.2005.04.030.

2004

Oligomeric structure of the Bacillus subtilis cell division protein DivIVA determined by transmission electron microscopy

H. Stahlberg; E. Kutejova; K. Muchova; M. Gregorini; A. Lustig et al. 

Molecular Microbiology. 2004-04-28. Vol. 52, num. 5, p. 1281-1290. DOI : 10.1111/j.1365-2958.2004.04074.x.

2003

Iplt-image processing library and toolkit for the electron microscopy community

A. Philippsen; A. Schenk; H. Stahlberg; A. Engel 

Journal of Structural Biology. 2003-10-01. Vol. 144, num. 01.févr., p. 4-12. DOI : 10.1016/j.jsb.2003.09.032.

Type III protein translocase – Hrcn is a peripheral membrane ATPase that is activated by oligomerization

C. Pozidis; A. Chalkiadaki; A. Gomez-Serrano; H. Stahlberg; I. Brown et al. 

Journal of Biological Chemistry. 2003-05-06. Vol. 278, num. 28, p. 25816-25824. DOI : 10.1074/jbc.M301903200.

2002

Assessing the structure of membrane proteins: combining different methods gives the full picture

H. Stahlberg; A. Engel; A. Philippsen 

Biochemistry and Cell Biology. 2002-10-01. Vol. 80, num. 5, p. 563-568. DOI : 10.1139/O02-160.

Progress in the analysis of membrane protein structure and function

P. Werten; H. Remigy; B. de Groot; D. Fotiadis; A. Philippsen et al. 

FEBS Letters. 2002-08-29. Vol. 529, num. 1, p. 65-72. DOI : 10.1016/S0014-5793(02)03290-8.

Sampling the conformational space of membrane protein surfaces with the AFM

S. Scheuring; D. Muller; H. Stahlberg; H. Engel; A. Engel 

European Biophysics Journal. 2002-06-01. Vol. 31, num. 3, p. 172-178. DOI : 10.1007/s00249-001-0197-8.

Charting and unzipping the surface layer of Corynebacterium glutamicum with the atomic force microscope

S. Scheuring; H. Stahlberg; M. Chami; C. Houssin; J. Rigaud et al. 

Molecular Microbiology. 2002-05-07. Vol. 44, num. 3, p. 675-684. DOI : 10.1046/j.1365-2958.2002.02864.x.

Aquaglyceroporins: Channel proteins with a conserved core, multiple functions, and variable surfaces

A. Engel; H. Stahlberg 

International Review of Cytology; 2002. p. 75-104.

2001

Two-dimensional crystals: a powerful approach to assess structure, function and dynamics of membrane proteins

H. Stahlberg; D. Fotiadis; S. Scheuring; H. Remigy; T. Braun et al. 

FEBS Letters. 2001-08-28. Vol. 504, num. 3, p. 166-172. DOI : 10.1016/S0014-5793(01)02746-6.

ATP synthase: constrained stoichiometry of the transmembrane rotor

D. Muller; N. Dencher; T. Meier; P. Dimroth; K. Suda et al. 

FEBS Letters. 2001-08-28. Vol. 504, num. 3, p. 219-222. DOI : 10.1016/S0014-5793(01)02708-9.

Bacterial Na+-ATP synthase has an undecameric rotor

H. Stahlberg; D. Muller; K. Suda; D. Fotiadis; A. Engel et al. 

EMBO reports. 2001-03-01. Vol. 2, num. 3, p. 229-233. DOI : 10.1093/embo-reports/kve047.

Electron Cryomicroscopy

J. Dubochet; H. Stahlberg 

Encyclopedia of Life Sciences; 2001. p. a0002999.

The aquaporin superfamily: Structure and function

H. Stahlberg; B. Heymann; K. Mitsuoka; Y. Fuyijoshi; A. Engel 

Aquaporins; Elsevier, 2001-01-01. p. 39-119.

2000

The 6.9-angstrom structure of GlpF: A basis for homology modeling of the glycerol channel from Escherichia coli

H. Stahlberg; T. Braun; B. de Groot; A. Philippsen; M. Borgnia et al. 

Journal of Structural Biology. 2000-11-01. Vol. 132, num. 2, p. 133-141. DOI : 10.1006/jsbi.2000.4317.

The 3.7 angstrom projection map of the glycerol facilitator GlpF: a variant of the aquaporin tetramer

T. Braun; A. Philippsen; S. Wirtz; M. Borgnia; P. Agre et al. 

EMBO reports. 2000-08-01. Vol. 1, num. 2, p. 183-189. DOI : 10.1093/embo-reports/kvd022.

Surface tongue-and-groove contours on lens MIP facilitate cell-to-cell adherence

D. Fotiadis; L. Hasler; D. Muller; H. Stahlberg; J. Kistler et al. 

Journal of Molecular Biology. 2000-07-01. Vol. 300, num. 4, p. 779-789. DOI : 10.1006/jmbi.2000.3920.

The aquaporin sidedness revisited

S. Scheuring; P. Tittmann; H. Stahlberg; P. Ringler; M. Borgnia et al. 

Journal of Molecular Biology. 2000-06-01. Vol. 299, num. 5, p. 1271-1278. DOI : 10.1006/jmbi.2000.3811.

Proton-powered turbine of a plant motor

H. Seelert; A. Poetsch; N. A. Dencher; A. Engel; H. Stahlberg et al. 

Nature. 2000-05-25. Vol. 405, num. 6785, p. 418-419. DOI : 10.1038/35013148.

Domain structure of secretin PulD revealed by limited proteolysis and electron microscopy

N. Nouwen; H. Stahlberg; A. Pugsley; A. Engel 

The EMBO Journal. 2000-05-15. Vol. 19, num. 10, p. 2229-2236. DOI : 10.1093/emboj/19.10.2229.

1999

High resolution AFM topographs of the Escherichia coli water channel aquaporin Z

S. Scheuring; P. Ringler; M. Borgnia; H. Stahlberg; D. Muller et al. 

The EMBO Journal. 1999-09-15. Vol. 18, num. 18, p. 4981-4987. DOI : 10.1093/emboj/18.18.4981.

Structure of the water channel AqpZ from Escherichia coli revealed by electron crystallography

P. Ringler; M. Borgnia; H. Stahlberg; P. Maloney; P. Agre et al. 

Journal of Molecular Biology. 1999-09-01. Vol. 291, num. 5, p. 1181-1190. DOI : 10.1006/jmbi.1999.3031.

Mitochondrial Lon of Saccharomyces cerevisiae is a ring-shaped protease with seven flexible subunits

H. Stahlberg; E. Kutejova; K. Suda; B. Wolpensinger; A. Lustig et al. 

Proceedings of the National Academy of Sciences. 1999-06-08. Vol. 96, num. 12, p. 6787-6790. DOI : 10.1073/pnas.96.12.6787.

The reaction center complex from the green sulfur bacterium Chlorobium tepidum: A structural analysis by scanning transmission electron microscopy

H. Remigy; H. Stahlberg; D. Fotiadis; S. Muller; B. Wolpensinger et al. 

Journal of Molecular Biology. 1999-04-01. Vol. 290, num. 4, p. 851-858. DOI : 10.1006/jmbi.1999.2925.

1998

Friction anisotropy and asymmetry of a compliant monolayer induced by a small molecular tilt

M. Liley; D. Gourdon; D. Stamou; U. Meseth; T. Fischer et al. 

Science. 1998-04-10. Vol. 280, num. 5361, p. 273-275. DOI : 10.1126/science.280.5361.273.

Are the light-harvesting I complexes from Rhodospirillum rubrum arranged around the reaction center in a square geometry?

H. Stahlberg; J. Dubochet; H. Vogel; R. Ghosh 

Journal of Molecular Biology. 1998. Vol. 282, num. 4, p. 819-831. DOI : 10.1006/jmbi.1998.1975.

The reaction center of the photounit of Rhodospirillum rubrum is anchored to the light-harvesting complex with four-fold rotational disorder

H. Stahlberg; J. Dubochet; H. Vogel; R. Ghosh 

Photosynthesis Research. 1998. Vol. 55, num. 2-3, p. 363-368. DOI : 10.1023/A:1005964123955.

1997

Chloroplast F0F1 ATP synthase imaged by atomic force microscopy

D. Neff; S. Tripathi; K. Middendorf; H. Stahlberg; H. Butt et al. 

Journal of Structural Biology. 1997-07-01. Vol. 119, num. 2, p. 139-148. DOI : 10.1006/jsbi.1997.3891.

1996

Sulfur-bearing lipids for the covalent attachment of supported lipid bilayers to gold surfaces: a detailed characterization and analysis

C. Duschl; M. Liley; H. Lang; A. Ghandi; S. M. Zakeeruddin et al. 

Materials Science and Engineering C. 1996. Vol. 4, num. 1, p. 7-18. DOI : 10.1016/0928-4931(95)00123-9.

The End.