Commentary on paper by Leroy C. Stevens (1960)

D. Duboule 

Impact of genome architecture on the functional activation and repression of Hox regulatory landscapes

E. Rodriguez-Carballo; L. Lopez-Delisle; N. Yakushiji-Kaminatsui; A. Ullate-Agote; D. Duboule 

Constrained Transcriptional Polarity In The Organization Of Mammalian Hox Gene Clusters

F. Darbellay; C. Bochaton; L. Lopez-Delisle; B. Mascrez; P. Tschopp et al. 

Tail Bud Progenitor Activity Relies on a Network Comprising Gdf11, Lin28, and Hox13 Genes

R. Aires; L. de Lemos; A. Novoa; A. D. Jurberg; B. Mascrez et al. 

Analysis of long-range gene regulation at the HoxD locus

Do RET somatic mutations play a role in Hirschsprung disease? Response

B. K. Kragesteen; D. Duboule; S. Mundlos; M. Spielmann 

Similarities and differences in the regulation of HoxD genes during chick and mouse limb development

N. Yakushiji-Kaminatsui; L. Lopez-Delisle; C. C. Bolt; G. Andrey; L. Beccari et al. 

Multi-axial self-organization properties of mouse embryonic stem cells into gastruloids

L. Beccari; N. Moris; M. Girgin; D. A. Turner; P. Baillie-Johnson et al. 

Coordinated Hoxd genes expression during embryogenesis is dependent on a strict disposition of genes and polarized regulators within the HoxD cluster

The HoxD cluster is a dynamic and resilient TAD boundary controlling the segregation of antagonistic regulatory landscapes.

E. Rodriguez-Carballo; L. Lopez-Delisle; Y. Zhan; P. J. Fabre; L. Beccari et al. 

Control of growth and gut maturation by &ITHoxD&IT genes and the associated lncRNA &ITHaglr&IT

J. Zakany; F. Darbellay; B. Mascrez; A. Necsulea; D. Duboule 

Large scale genomic reorganization of topological domains at the HoxD locus

P. J. Fabre; M. Leleu; B. H. Mormann; L. Lopez-Delisle; D. Noordermeer et al. 

Integration of Shh and Fgf signaling in controlling Hox gene expression in cultured limb cells

A. R. Rodrigues; N. Yakushiji-Kaminatsui; Y. Atsuta; G. Andrey; P. Schorderet et al. 

Hox Genes Regulation During Vertebrate Development and Evolution

F. Darbellay; J. Zakany; B. Mascrez; D. Duboule 

Embryonic timing, axial stem cells, chromatin dynamics, and the Hox clock

J. Deschamps; D. Duboule 

KRAB’n’KAP, DNA methylation and epigenetic memory

Hotair Is Dispensible for Mouse Development

A. R. Amandio; A. Necsulea; E. Joye; B. Mascrez; D. Duboule 

Control of Hoxd gene transcription in the mammary bud by hijacking a preexisting regulatory landscape

R. Schep; A. Necsulea; E. Rodriguez-Carballo; I. Guerreiro; G. Andrey et al. 

Reorganisation of Hoxd regulatory landscapes during the evolution of a snake-like body plan

I. Guerreiro; S. Gitto; A. Novoa; J. Codourey; H. Thi Hanh Nguyen et al. 

A role for HOX13 proteins in the regulatory switch between TADs at the HoxD locus

L. Beccari; N. Yakushiji-Kaminatsui; J. M. Woltering; A. Necsulea; N. Lonfat et al. 

Nanoscale Spatial Organization of Chromatin in its Cellular Context, from Telomeres to Hox

S. Manley; K. Douglass; V. Pfeiffer; A. Vancevska; P. Fabre et al. 

A genetic approach of long-range gene regulation during development and evolution

D. Duboule 

From the early steps of whisker formation to its evolutionary disappearance: the (curious) case of Prdm1 and its regulation

Topological Domains, Metagenes, and the Emergence of Pleiotropic Regulations at Hox Loci

F. Darbellay; D. Duboule 

Nanoscale spatial organization of the HoxD gene cluster in distinct transcriptional states

P. J. Fabre; A. Benke; E. Joye; T. H. Nguyen Huynh; S. Manley et al. 

Tetrapod axial evolution and developmental constraints; Empirical underpinning by a mouse model

J. M. Woltering; D. Duboule 

Structure, function and evolution of topologically associating domains (TADs) at HOX loci

N. Lonfat; D. Duboule 

Clustering of mammalian Hox genes with other H3K27me3 targets within an active nuclear domain

M. Vieux-Rochas; P. J. Fabre; M. Leleu; D. Duboule; D. Noordermeer 

Visualizing the HoxD Gene Cluster at the Nanoscale Level

P. J. Fabre; A. Benke; S. Manley; D. Duboule 

Convergent evolution of complex regulatory landscapes and pleiotropy at Hox loci

N. Lonfat; T. Montavon; F. Darbellay; S. Gitto; D. Duboule 

Considerations when investigating IncRNA function in vivo

A. R. Bassett; A. Akhtar; D. P. Barlow; A. P. Bird; N. Brockdorff et al. 

Attenuated sensing of SHH by Ptch1 underlies evolution of bovine limbs

J. Lopez-Rios; A. Duchesne; D. Speziale; G. Andrey; K. A. Peterson et al. 

Temporal dynamics and developmental memory of 3D chromatin architecture at Hox gene loci

D. Noordermeer; M. Leleu; P. Schorderet; E. Joye; F. Chabaud et al. 

Evolving Hox Activity Profiles Govern Diversity in Locomotor Systems

H. Jung; E. Mazzoni; N. Soshnikova; O. Hanley; B. Venkatesh et al. 

SnapShot: Hox Gene Regulation

G. Andrey; D. Duboule 

Conservation and Divergence of Regulatory Strategies at Hox Loci and the Origin of Tetrapod Digits

J. M. Woltering; D. Noordermeer; M. Leleu; D. Duboule 

The king cobra genome reveals dynamic gene evolution and adaptation in the snake venom system

F. J. Vonk; N. R. Casewell; C. V. Henkel; A. M. Heimberg; H. J. Jansen et al. 

A Genetic Approach to the Recruitment of PRC2 at the HoxD Locus

P. Schorderet; N. Lonfat; F. Darbellay; P. Tschopp; S. Gitto et al. 

Topology of mammalian developmental enhancers and their regulatory landscapes

W. De Laat; D. Duboule 

Multiple Enhancers Regulate Hoxd Genes and the Hotdog LncRNA during Cecum Budding

S. Delpretti; T. Montavon; M. Leleu; E. Joye; A. Tzika et al. 

Role of a polymorphism in a Hox/Pax-responsive enhancer in the evolution of the vertebrate spine

I. Guerreiro; A. Nunes; J. M. Woltering; A. Casaca; A. Novoa et al. 

Combined function of HoxA and HoxB clusters in neural crest cells

M. Vieux-Rochas; B. Mascrez; R. Krumlauf; D. Duboule 

A switch between topological domains underlies HoxD genes collinearity in mouse limbs

G. Andrey; T. Montavon; B. Mascrez; F. Gonzalez; D. Noordermeer et al. 

Chromatin architectures and hox gene collinearity

D. Noordermeer; D. Duboule 

Duplications of hox gene clusters and the emergence of vertebrates

N. Soshnikova; R. Dewaele; P. Janvier; R. Krumlauf; D. Duboule 

Chromatin looping and organization at developmentally regulated gene loci

D. Noordermeer; D. Duboule 

An ancestral regulatory mechanism underlies Hoxd gene expression in both developing genitals and digits

Regulatory Switches Underlie Hoxd Gene Activation in Tetrapod Limbs

Polycomb Recruitment and Targeting in Mammals

Mechanisms of Hoxd gene regulation during the development and evolution of the intestinal caecum

A Genetic Basis for Altered Sexual Behavior in Mutant Female Mice

J. Zakany; D. Duboule 

Landscapes and archipelagos: spatial organization of gene regulation in vertebrates

T. Montavon; D. Duboule 

A function for all posterior Hoxd genes during digit development?

S. Delpretti; J. Zakany; D. Duboule 

Bimodal control of Hoxd gene transcription in the spinal cord defines two regulatory subclusters

P. Tschopp; A. J. Christen; D. Duboule 

A regulatory archipelago controls hox genes transcription in digits

T. Montavon; N. Soshnikova; B. Mascrez; E. Joye; L. Thevenet et al. 

A genetic approach to the transcriptional regulation of hox gene clusters

P. Tschopp; D. Duboule 

The dynamic architecture of Hox gene clusters

D. Noordermeer; M. Leleu; E. Splinter; J. Rougemont; W. De Laat et al. 

Analysis of the dynamics of limb transcriptomes during mouse development

I. Gyurján; B. Sonderegger; F. Naef; D. Duboule 

Structural and functional differences in the long non-coding RNA hotair in mouse and human

P. Schorderet; D. Duboule 

Reshuffling genomic landscapes to study the regulatory evolution of Hox gene clusters

P. Tschopp; N. Fraudeau; F. Béna; D. Duboule 

A regulatory ‘landscape effect’ over the Hoxd cluster

P. Tschopp; D. Duboule 

Lentiviral vectors mediated transgenesis

S. Verp; M. Blom; M. Friedli; S. Delpretti; I. Barde et al. 

A systematic enhancer screen using lentivector transgenesis identifies conserved and non-conserved functional elements at the olig1 and olig2 locus

M. Friedli; I. Barde; M. Arcangeli; S. Verp; A. Quazzola et al. 

Functional analysis of CTCF during mammalian limb development

N. Soshnikova; T. Montavon; M. Leleu; N. Galjart; D. Duboule 

Changes in Hox genes’ structure and function during the evolution of the squamate body plan

N. Di-Poï; J. I. Montoya-Burgos; H. Miller; O. Pourquié; M. C. Milinkovitch et al. 

Additive and global functions of HoxA cluster genes in mesoderm derivatives

N. Di-Poï; U. Koch; F. Radtke; D. Duboule 

The origin of digits: expression patterns versus regulatory mechanisms

J. M. Woltering; D. Duboule 

Homeobox genes d11-d13 and a13 control mouse autopod cortical bone and joint formation

P. Villavicencio-Lorini; P. Kuss; J. Friedrich; J. Haupt; M. Farooq et al. 

The evo-devo comet

D. Duboule 

The Hox complex – an interview with Denis Duboule. Interviewed by Richardson, Michael K

D. Duboule 

Epigenetic temporal control of mouse Hox genes in vivo

N. Soshnikova; D. Duboule 

Epigenetic regulation of Hox gene activation: the waltz of methyls

N. Soshnikova; D. Duboule 

Ectopic nuclear reorganisation driven by a Hoxb1 transgene transposed into Hoxd

C. Morey; N. R. Da Silva; M. Kmita; D. Duboule; W. A. Bickmore 

Characterization of mouse Dactylaplasia mutations: a model for human ectrodactyly SHFM3

M. Friedli; S. Nikolaev; R. Lyle; M. Arcangeli; D. Duboule et al. 

Genotypic features of lentivirus transgenic mice

M-O. Sauvain; A. P. Dorr; B. Stevenson; A. Quazzola; F. Naef et al. 

Global Control Regions and Regulatory Landscapes in Vertebrate Development and Evolution

F. Spitz; D. Duboule 

Direct Reprogramming of Terminally Differentiated Mature B Lymphocytes to Pluripotency

P. Schorderet 

Hoxd gene regulation in the developing caecum

S. Delpretti; T. Montavon 

The rise and fall of Hox gene clusters

D. Duboule 

The European dimension for the mouse genome mutagenesis program

J. Auwerx; P. Avner; R. Baldock; A. Ballabio; R. Balling et al.