Zenk Lab – NeuroNA Chair in Epigenomics of Neurodevelopment – EpiGN

Human brain organoid

Human Brain Organoid overlayed with a force directed layout visualizing the developmental trajectories of the major brain regional branches. © EPFL-Zenk Lab

The EpiGN laboratory is dedicated to unraveling the intricate processes that give rise to a multitude of cell types and regional identities within the human brain during embryonic development, all stemming from a single progenitor cell. Our investigative approach involves using brain organoids, single-cell genomics, and computational tools to investigate the epigenetic mechanisms orchestrating the precise gene expression programs encoded within our DNA.