Trono Lab – Laboratory of Virology and Genetics

Our research interest are Krab-Zinc finger protein, transposons and epigenetics.

Shown here is the internal, self-organised structure of a stem cell derived, human cerebral organoid. Rosettes of neural progenitor SOX2 positive radial glia (red) are interspersed with TUJ1 positive newborn neurons (green). Nuclei are marked in blue | © Christopher Playfoot & Didier Trono

Colorectal cancer is one of the most common forms of cancer in the Western world. © Stock

Genetic discovery could improve treatment of colorectal cancer

Published:30.08.22 — EPFL scientists have discovered a rare gene in the tumors of some colorectal cancer patients. This finding could lead to more accurate diagnoses and, eventually, personalized treatments that target the protein expressed by the gene.

a) Cryo-EM map of omicron spike b) Model of of Omicron spike built into Cryo-EM map. c) Model of one monomer of Omicron spike showing all the mutations present. © 2021 EPFL

Omicron's secrets revealed under a microscope

Published:29.12.21 — Thanks to the high-power electron microscopes at the Dubochet Center for Imaging (DCI), EPFL scientists were able to observe the configuration of the Omicron variant’s spike protein at a near-atomic scale. This should provide fresh insight into the mechanisms the variant uses to evade vaccines and antibodies.

Our top ten news articles from 2021

Published:24.12.21 — We published nearly 300 news articles on EPFL’s homepage in 2021, detailing the latest developments in science, academics, student life, startups and EPFL in general. However, these articles provide only a glimpse of the many exciting things going on at our School in research, education and innovation. Here’s a summary of the ten most-read news stories from 2021.

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