Laboratory of Experimental Biophysics

Welcome to LEB!
We study organelle structure, dynamics, and function. We focus on the mitochondrial life cycle and physiology, as well as how they are governed by inter-organelle contact sites. To do this, we develop smart and super-resolution fluorescence microscopy methods. Our goal is to enable gentler live cell imaging at the necessary temporal and spatial resolutions. Our smart microscopes adapt the measurement to the sample in real time, changing the speed, channel, location, or perturbation as needed.
In the News
Pearling drives mitochondrial DNA nucleoid distribution. Prof. Janet Iwasa created this animation to capture our discoveries about this process.
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Video interview for EPFL’s 50th anniversary campaign on female leadership in science
Comic strip project on the lab’s discoveries about mitochondrial divisions by Vivienne Baillie Gerritsen and Adrienne Barman for Dimensions Magazine
Interview with infocus Magazine, “20 Questions with Professor Suliana Manley, Winner of 2018 Medal for Light Microscopy”
Positions
Masters, doctoral and post-doctoral positions are available. We seek enthusiastic, motivated scientists of all backgrounds.

