Welcome to the Laboratory of Asymmetric Catalysis and Synthesis headed by Professor Nicolai Cramer. We are a young and dynamic research team working on challenges in the areas of asymmetric metal-catalyzed reactions and the synthesis of bioactive natural products.
LATEST NEWS
10.01.2022: Felix Seeberger joined the group as visiting PhD student. Welcome Felix!
12.11.2021: Elena successfully defended his thesis. Congrats Elena!
03.11.2021: Jin Fay Tan successfully defended his thesis. Congrats Jin Fay!
01.11.2021: Enzo Martin joined the group as new PhD student. Welcome Enzo!
28.10.2021: Elena’s work on crossed enantioselective iron-catalyzed [4+2]-cycloaddition is published in ACIE. Congrats!
13.09.2021: Ana’s work on asymmetric Co(III)-catalyzed three-component C-H functionalizations is published in ACS Catal. Congrats!!
01.09.2021: Seongmin Jeon joined the group as new PhD student. Welcome Seongmin!
22.06.2021: Lukasz Ir-catalyzed atropselective oxidative C-H arylation is published in ACIE. Congrats!
03.06.2021: Our longstanding collaboration with the Severin group on alkynyl triazenes resulted in another great result, see Chem Sci publication for Jin-Fay. Congrats!
28.04.2021: Qui-Hien Nguyen successfully defended his thesis. Congrats Hien!
23.04.2021: Josep’s full paper on iridium-catalyzed ionic hydrogenation of the Syngenta collaboration is published in ACIE. Congrats Josep and Tomas!
19.04.2021: Dr. Guoting Zhang joined the group. Welcome Guoting!
01.04.2021: Anastasiia Vorobei joined the group. Welcome Anastasiia!
16.12.2020: John Reed successfully defended his thesis. Congrats Jack!
11.12.2020: Benoit Audic successfully defended his thesis. Congrats Benoit!
01.12.2020: Bram van den Bossche joined the group as new PhD student. Welcome Bram!
23.11.2020: Aragorn’s creative Cp-complexation strategy is published in Organometallics. Congrats Aragorn!
11.11.2020: The enantioselective iron-catalyzed [4+4]-cycloaddition is published in JACS. Congrats to Elena and Alissa!!
01.11.2020: Arthur Despois joined the group as new PhD student. Welcome Arthur!
28.9.2020: Kristers and Shunsuke’s enantioselective Cobalt-catalysis is published in ACIE. Congrats!
11.09.2020: Elena and Josep won the runner-up prizes for the best poster and oral presentation, respectively, at the SCS fall meeting. Congrats!
11.09.2020: Beatriz Saveedra Guillem from Alicante joined the group as exchange PhD student. Welcome Beatriz!
08.09.2020: The groups review on asymmetric Ir-catalyzed C-H functionalizations is online in Chem. Rev., congrats!
05.09.2020: Josep’s work on Ir-catalyzed asymmetric oxime hydrogenation is now on YouTube! Check it out!! Thanks to Dr. Matthew Horwitz for the invitation at the Synthesis Workshop.
03.09.2020: Jack’s review on phospholene catalysis is online in OCF, congrats!
16.07.2020: The group’s review on chiral Cp ligands is published in ACIE, congrats to the whole team!!
01.07.2020: Dr. Zhen Chen and Dr. Ouidad Lahtigui joined the group, welcome!
29.06.2020: Shou-Guo’s [4+1] functionalization with acrylic acids is published in ACS Catalysis, congrats!
17.06.2020: Benoit’s report on rhodium(III)-catalyzed cyclopropane C-H/C-C functionalization is published in Org. Lett., congrats!
10.06.2020: Elena’s work on chiral naphthyridine ligands for Ni-catalyzed alkylidenecyclopropanations is published in Angewandte, congrats!
05.06.2020: Josep’s powerful Cpx-Iridium hydrogenation of oximes is published in Science, congrats! Results of a great collaboration with Tomas Smejkal at Syngenta!
27.05.2020: Jack’s work on diazaphospholenes appeared in ChemCatChem, congrats!!!
15.05.2020: Coralie’s paper on asymmetric Rh-catalyzed carboamination is published in ACIE, congrats!!!
03.04.2020: Sung Hwan Park successfully defended his PhD thesis at EPFL! Congrats!!
02.03.2020: Dan Forster joins the group as Master student. Welcome Dan!
02.03.2020: Work of Jin-Fay is now published in ACS Catalysis, well done!
01.02.2020: Johannes Klett joins the group for his PhD thesis. Welcome Johannes!
02.03.2020: The paper of Hien on atroposelective Pd-catalyzed C-H functionalization is now in JACS, congrats!! Great collaboration with Olivier Baudoin in Basel!
LATEST PUBLICATIONS
E. Braconi, N. Cramer, Angew. Chem. Int. Ed. 2021, DOI: 10.1002/anie.202112148: “Crossed Regio- and Enantioselective Iron-Catalyzed [4+2]-Cycloadditions of Unactivated Dienes”
A. G. Herraiz, N. Cramer, ACS Catal. 2021, DOI: 10.1021/acscatal.1c03153: “Cobalt(III)-Catalyzed Diastereo- and Enantioselective Three-Component C–H Functionalization”
L. Wozniak, N. Cramer, Angew. Chem. Int. Ed. 2021, 60, 18532-18536: “Atropo-Enantioselective Oxidation-Enabled Iridium(III)-Catalyzed C–H Arylations with Aryl Boronic Esters”
J.-F. Tan, C. T. Bormann, K. Severin, N. Cramer, Chem. Sci. 2021, 12, 9140-9145: “Alkynyl Triazenes Enable Divergent Syntheses of 2-Pyrones”
J. Mas-Rosello, C. J. Cope, E. Tan, B. Pinson, A. Robinson, T. Smejkal, N. Cramer, Angew. Chem. Int. Ed. 2021, 60, 15524–15532 : “Iridium-Catalyzed Acid-Assisted Hydrogenation of Oximes to Hydroxylamines”
K. Ozols, S. Onodera, L. Wozniak, N. Cramer, Angew. Chem. Int. Ed. 2021, 60, 655-659: “Cobalt(III)-Catalyzed Enantioselective Intermolecular Carboaminations via C-H Functionalizations”
J. Mas-Roselló, A. G. Herraiz, B. Audic, A. Laverny, N. Cramer, Angew. Chem. Int. Ed. 2021, 60, 13198-13244: “Chiral cyclopentadienyl ligands: design, syntheses and applications in asymmetric catalysis”
K. Ozols, S. Onodera, L. Wozniak, N. Cramer, Angew. Chem. Int. Ed. 2021, 60, 655-659: “Cobalt(III)-Catalyzed Enantioselective Intermolecular Carboaminations via C-H Functionalizations”