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Learning how to control HIV from African genomes

— A study on almost four thousand people of African descent has identified a gene that acts as natural defense against HIV by limiting its replication in certain white blood cells. An international effort co-led by EPFL, Canada’s National Microbiology Laboratory, and Imperial College London, it paves the way for new treatment strategies and underscores the importance of studying diverse ancestral populations to better address their specific medical needs and global health disparities.

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Oral bacteria may increase heart disease risk

— Researchers at EPFL have found that infection with a common bacterium that is linked to periodontal disease, oral cancers, and bad breath may cause a small increase in the risk of cardiovascular disease.

EPFL professor Jacques Fellay has been selected for a new advisory committee that the government set up recently so policymakers and scientists can continue their joint efforts. © Alain Herzog/EPFL

“Scientists can never make statements with 100% certainty”

— EPFL professor Jacques Fellay, who served on the Swiss National Covid-19 Task Force, has been selected for a new advisory committee that the government set up recently so policymakers and scientists can continue their joint efforts.

Parliament Square in Bern, Switzerland, 4 April 2020 © iStock

Switzerland's lockdown has sharply reduced the cases of COVID-19

— EPFL researchers have modeled the effects of measures taken in the country to slow the spread of coronavirus. According to their estimates, the contamination rate has fallen by between 53% and 92%, depending on the canton, and people’s movements have been reduced by 30% to 80%.

Jacques Fellay (credit: Alain Herzog, EPFL)

“The world now has no choice but to count on science.”

— Jacques Fellay, a professor at EPFL’s School of Life Sciences, talks about mutations of the novel coronavirus, variants in the human genome, and how they might affect the current pandemic.

© 2019 EPFL

Prof. Jacques Fellay promoted to Associate Professor

— Professor Jacques Fellay was named as Associate Professor of Life Sciences in the School of Life Sciences (SV).

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Differences in immune responses due to age, sex, and genetics

— Age, sex, and specific human genetic variants are the key factors behind differences between immune responses among healthy humans, finds a study of 1,000 individuals carried out by EPFL and the Pasteur Institute.

Jacques Fellay

Jacques Fellay wins 2017 SSI Award

— Professor Jacques Fellay was awarded the Swiss Society for Infectious Diseases (SSI) award for his work on severe respiratory illness in children.

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The genetics of severe illness in children with the common cold

— EPFL scientists have discovered gene variants that make children life-threatening susceptible to common-cold viruses.

An influenza virus binding to a lung cell (© CDC)

Genetic variation is key to fighting viruses

— Using a genome-wide association study, EPFL scientists have identified subtle genetic changes that can cause substantial differences to how we fight viral infections.

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