Advancing high-resolution microscopes to enable time-lapse nano-characterization of pathogenic micro-organisms in-vitro

Rational cytokine and receptor engineering for enhanced safety and efficacy of cancer immunotherapy

Heartbeat on repeat: noncanonical KZFP and its transposable element targets shape cardiac cell specification

Exploring ion and analyte transport in beta-barrel forming biological nanopores

Accessible and highly observable gastrointestinal organoid model systems for studying host-pathogen interactions

3DReact: Geometric Deep Learning for Chemical Reactions

P. van Gerwen; K. R. Briling; C. Bunne; V. R. Somnath; R. Laplaza et al. 

Quantitative characterization of the inorganic phosphate gene regulatory networks in S. cerevisiae and bottom up engineering an orthogonal gene network

Resolving bacterial cell biology: from replisome dynamics to cell wall synthesis

Advancements in Nanomechanical Characterization and Biomolecular Imaging with Atomic force Microscopy

Characterization of the gut-bone marrow axis through bile acid signaling

ER+ breast cancer in 3D scaffold ex vivo for transcriptomics-based functional drug screening and personalized medicine

Drug Screening in C. elegans to identify new pharmacological mitochondrial stress inducers

Unraveling behavior and cortical signals to guide the development of soft neuroprostheses for auditory restoration and spreading depolarization

Engineering Split HaloTag for Advanced Fluorescence Microscopy

Engineering novel protein interactions with therapeutic potential using deep learning-guided surface design

Exploring the therapeutic potential of Huntingtin native state stabilization through targeting its interacting partners

Unraveling mitochondrial dynamics: exploring asymmetries and function through advanced microscopy

The Slc25a47-Wars1 locus: characterization of its role in metabolic homeostasis and stress pathways

Dielectrophoretic Manipulation of Biological Species: Novel Microfluidic Approaches to Study Cell-Cell Interactions and the Role of Alpha-Synuclein in Neurodegeneration

Bioengineering functional organoid models across scales

Advancing Cell-Free Synthetic Biology: From sustained PURE protein synthesis to an isothermal one-pot DNA replication system

Multi-motif scaffolding for de novo pathogen antigen mimetics by deep generative learning

Single-cell analysis of the interactions between Mycobacterium tuberculosis and macrophages

Targeting TDP-43 Proteinopathies in Neurodegeneration by its Native-State Stabilization

Development and evaluation of a near-infrared photovoltaic implant for wireless neural stimulation

Targeting Cellular Senescence and NAD⁺ Metabolism Disruption in Early-Stage Chronic Kidney Disease

Compliance-matching vascular grafts with personalization potential

Bioengineering human mini-intestines with in vivo-like complexity and function

Bacterial colonization in realistic environments: how mechanics impact biofilm formation in the wild and during infection

Advancing atomic force microscopy through open source instrumentation

The Effects of Spatial Organization and Fluid Flow on the Social Interactions in Microbial Communities

Novel quantitative bioengineered tools to track human bone marrow niche cellular constituents in health and disease

Engineering Innate and Adaptive Immunity for Enhanced Cancer Immunotherapy

Engineering Hydrogel-coated Neural Interfaces for Chronic Deep Brain Recording

Exploring the interplay of molecular pattern and valency for selective interactions at the bio-interface

Time-Resolved Scanning Ion Conductance Microscopy and Single-Molecule Spectroscopy

Countering T cell exhaustion and senescence for enhanced adoptive T cell therapies against solid tumors

Identifying genetic and dietary modulators of metabolic disorders using systems genetics

Label-free plasmonic microarray for multiplexed analysis of cells and tumor organoids

Development of new volcano-shaped microelectrodes for single cell electrochemistry, electrophysiology and impedance studies

Nanotechnology enabled modulation of T cell immunity for cancer treatment

Characterization of Cyclo His-Pro for the prevention and treatment of liver disease and muscular dystrophy

How are cells instructed to form somite boundaries by the zebrafish segmentation clock?

Cross-anatomical single-cell definition and characterization of human adipose progenitor niche

Tracking spatiotemporal localisation and interactions of the innate immune sensor STING

Towards automating de novo protein design for novel functionalities: controlling protein folds and protein-protein interactions

Molecular Regulation of Muscle Stem Cell Fate during Skeletal Muscle Regeneration and Aging

Multidisciplinary Investigation of the Gut-Brain Ecosystem in a Model of Alzheimer’s Disease

Systematic analysis of biomolecular binding reactions using microfluidic systems

Identification of genes required for host-cell adhesion and antibiotic persistence of uropathogenic Escherichia coli via high-content screening

Engineering T Cell Trafficking and Function for Enhanced Cancer Immunotherapy

Understanding the mechanisms of non-thermal plasma treatments on seeds

Hunting for the wavefront: investigation of somite boundary positioning in zebrafish

Sensor-integrated ultraflexible endovascular devices

In vitro endoderm emergence and self-organisation in the absence of extraembryonic tissues and embryonic architecture

DNA-based biomaterials for nanoscale controlled modulation of immune cells

Rational design of protein switches: applications in synthetic biology and cancer immunotherapy

Methods for acute and long-term imaging of the ventral nerve cord in behaving adult Drosophila

Dissecting the role of biliary epithelial cells during non-alcoholic fatty liver disease progression

Characterization of Pseudomonas aeruginosa mechanosensing through label-free imaging of type IV pili

Targeting molecular surfaces to engineer novel protein-based immunogens and inhibitors

Dissecting the role of the asparagine synthesis in acute liver injury

Engineering synthetic adhesins for biophysical investigation and rewiring of host-microbe interactions

Fabrication and validation of an intraneural interface tailored for optic nerve stimulation

Development of a Transient Neural Interface for Minimally Invasive Recording and Stimulation

Enhancing mitochondrial quality control to fight neuromuscular degeneration in aging and disease

Co-regulation of endothelial and myogenic cell fates through intercellular crosstalk in skeletal muscle

On the exploration of novel methodological approaches for immunogen design: case studies in influenza and hepatitis C

Non-invasive monitoring of key hemodynamical and cardiac parameters using physics-based modelling and artificial intelligence

Toward a mechanistic understanding of variable chromatin modules

Genetic, metabolic, and molecular insights into the diverse outcomes of diet-induced obesity in mouse

KRAB zinc finger protein-mediated control of transposon-embedded regulatory sequences from human germline to early embryos

Microtissue models for studying the dynamics of host-pathogen interactions in the urinary bladder

Mechanical principles of engineering fibrous tissues with programmable shape

Biophysical applications of correlative scanning probe and super-resolution microscopy

The genetic architecture of complex human traits at the dawn of genomic medicine

In situ photopolymerizable hydrogels for intracranial aneurysms treatment

Towards scalable and deterministic single cell gene expression profiling

Development and applications of hyperpolarized 13C and 1H MR spectroscopy of cerebral metabolism at ultra-high field

Towards an artificial cell: Development of a system which self-regenerates the protein components of the PURE system in microfluidic reactors

An autonomous microfluidic device for identification and analysis of individual clinically-relevant mammalian cells

Engineering next generation organoids through guided stem cell self-organisation

Post-translational regulation of neuronal differentiation

Microfluidics and cell-free synthetic biology in the development of new diagnostic and therapeutic platforms

Circadian dynamics of RNA localisation in the mammalian liver

Towards engineering an artificial neural tube

Coordination between cell growth, division and chromosome replication cycles in mycobacteria

Single-cell lipidomics reveals a role for cell-to-cell sphingolipid heterogeneity in fibroblast activation

Organisation and dynamics of mitochondria and their RNA.

Decoding of error-related potentials in continuous feedback protocols for personalized human computer interaction

Wireless soft microscale actuators and robotic devices to study mechanobiology

Developing new tools to study and program cell fate at the single-cell level

Reprogramming G Protein-Coupled Receptor Structure, Function And Signaling By Computational Design

Functional de novo Protein Design for Targeted Vaccines and Synthetic Biology Applications

In vitro modeling of early mouse development

Metabolic rescue of muscle and muscle stem cells in muscle disease

Hemodynamics of ageing, ventricular-arterial coupling and noninvasive assessment of key hemodynamical and cardiac quantities

Quantitative approaches to unravel bone marrow adipocyte site-specificity and its implication in hematopoiesis

Beneficial axis of the renin-angiotensin system: from applications to drug discovery

Sensor and the Beast: Generalised Methods to Recognise Animal Behaviour and Quantify Energy Expenditure Using Inertial Sensors, and Applications

Bioengineering Methods to Improve in vitro Adoptive Cell Therapy based on Tumor-Infiltrating Lymphocytes

Time-lapse high-resolution microscopy to study the morphogenesis of microorganisms

Gait analysis in children with cerebral palsy: bridging the gap between the laboratory and real life

Development of novel methods and tools to decipher the huntingtin post-translation modifications code

Microfluidic devices for the study of cell-cell, cell-particle and particle-particle interactions

Characterization of Protein-Membrane Interfaces through a Synergistic Computational-Experimental Approach

Multidisciplinary Approach to Treat Erectile Dysfunction

Microfluidic iMITOMI platform to study the architecture of low-affinity transcription factor binding site clusters

High-throughput microfluidic platforms for characterizing and engineering cell-free gene regulatory circuits

Application of anti-amyloid beta immunization using encapsulated cell technology in mouse models of Alzheimer’s disease

The onset of cardiovascular disease in mice: an image-based, computational-experimental approach

Elucidating regulatory mechanisms shaping the transcriptome and proteome of the gut immune response in Drosophila melanogaster

Label-free plasmonic biosensors for real-time live cell analysis

2D nanopores: fabrication, energy harvesting and field-effect sensing

Modeling hematopoietic stem cell dynamics in bioengineered niches

Soft multimodal neural interfaces for unravelling sensory neurological circuits

Metabolic and microenvironmental strategies to accelerate hematopoietic recovery post-aplasia

Engineering Dynamic Hydrogels For In Vitro Organoid Culture

Single-cell studies of Mycobacterium smegmatis cell cycle using time-lapse fluorescence microscopy

Tailoring the Mechanical Properties of Tissue Engineering Scaffolds made from Decellularized Cartilage

Bioengineering the Human Muscle Stem-Cell Niche for Therapeutic Applications

Microchannel-based technologies for nerve interfacing

Optical projection tomography for whole organ imaging

Tissue-specific circadian transcriptional regulation

Integrated microfluidic tools for the characterization of protein/DNA interactions in vitro and in vivo

Structural and functional characterisation of the KRAB-domain associated protein 1

Bioengineering human bone marrow models to elucidate the triggers of the stem cell niche

Anti-angiogenic immunotherapy for lung cancer

Characterization of Coenzyme Q Biosynthesis Proteins through Integrative Modeling at the Protein-Membrane Interface

The role of OCT4 and SOX2 in regulating chromatin accessibility and cell fate across the cell cycle in embryonic stem cells

Expanding beyond the natural protein repertoire to engineer targeted vaccines and diagnostics

Introducing tolerance to foreign and partly foreign proteins by erythrocyte binding and artificial glycosylations

Circadian clock- and feeding-dependent regulation of translation initiation and elongation in the liver

Mid-Infrared plasmonic nanoantennas for ultrasensitive detection of proteins and their secondary structure

Computational and Statistical analyses of Molecular Evolution and Demography using Large-scale Sequencing Data

Quantitative analysis of gene expression and transcriptional memory in mouse embryonic stem cells

More Medicines for Tuberculosis: Fuelling Drug Discovery against Mycobacterium tuberculosis

Novel tools to dissect stem cell metabolism at single cell level

Ultra high magnetic field for glial contribution into brain metabolism studied by MR spectroscopy and CEST methods for molecular imaging of glycogen

Electronic dura mater soft, multimodal neural interfaces : technology, integration and implementation to surface implants

Single-cell division and killing dynamics of bacteria exposed to isocratic and time-dependent concentrations of antibiotic

In vitro fate mapping of stem cell development at the single cell level

The phenotypic impact of naturally occurring genetic and molecular mitochondrial variation in a Drosophila Genetic Reference Population

Modeling and analysis of parts and devices of genetic regulation

Constrained optimization applied to multiscale integrative modeling

Mitochondrial stress signalling and its impacts on physiology

Genetic determinants of healthy human immune variance: from humoral response to microbiome diversity

What is the role of fish intestine as environment-organism barrier? Mechanistic investigations using fish intestinal cells on a chip

New roles of the lymphatic endothelium in modulating adaptive immunity: implications for immune tolerance and cancer immunotherapy

Quantitative analysis of SOX2 and OCT4 expression in pluripotency and differentiation

Quantitative single cell dynamics of signaling and transcriptional response in mammalian cells

Development of microfluidic tools and methods for the biochemical characterization of scFv and Cas9 affinity reagents and their applications in molecular detection

Likelihood-free Inference of Population Genetic Parameters from Time-Sampled Genetic Data

Advancing immunotherapy for HPV-related cancers: Improving therapeutic vaccination approaches and understanding the immunosuppressive role of myeloid cells

A Microfluidic Brain Interface for In Vivo Recording of Neurochemical Activity

Gene regulatory dynamics underlying brown fat cell differentiation

The role of the polyglutamine and N-terminal domains in regulating the aggregation and structural properties of Huntingtin Exon 1

Lipid membrane characterization with second harmonic scattering : surface potentials, ionization, membrane asymmetry and hydration

Investigating the Biological Mechanisms underlying the Initiation of Autoimmunity against Beta Cell Antigens in Type 1 Diabetes

Cell lineage tracing in human tissues using somatic mitochondrial mutations

Fighting preterm birth with novel surgical tools and biomaterials engineering

A Microfluidic Platform Enables Large-Scale Single-Cell Screening to Identify Genes Involved in Bacterial Persistence

Novel systems biology approaches for design and analysis of palmitoylation networks reveal its regulatory effects on protein stability, activity and localization

Group Decisions Influence Emergence and Regulation of Leaders during Collective Migration of Epithelial Cells

Deciphering the subcapsular epithelial cells in human fetal and postnatal thymus

Human and eco-toxicological impacts of organometallic halide perovskites

Elucidating the role of lymphatic vessels within the tumor microenvironment of breast cancer

Nanocapillaries combined with optical tweezers as a single molecule technique for studying DNA-protein complexes

Exploring the potency of normal and pathological human thymic epithelial cells

Microfluidic and Electrokinetic Manipulation of Single Cells

Role of ACMSD in regulation of NAD+ metabolism and mitochondrial function

Microfluidic platforms for high-throughput mammalian cell printing, transfection, and dosage-dependent studies

Selective electrical and optical neuromodulation of the central nervous system with conformable microfabricated implants

AAV based gene therapy for rare diseases : targeting astrocytes for functional recovery in Amyotrophic Lateral Sclerosis

In vitro modeling of complex microenvironmental regulation of stem cells

Advanced technologies to control stem-cell based organogenesis

The therapeutic role of NAD+ modulation in fatty liver disease

Computational methods and modeling of cellular function for the optimization of protein production and the study of cellular disease states

Evaluation of oxidation-sensitive polymersomes as vaccine nanocarriers to enhance humoral responses against arenavirus envelope glycoproteins

Inferring the age and strength of mutations evolving under positive selection

Regulation of Endoplasmic Reticulum Architecture by Protein S-Palmitoylation

Mitochondrial unfolded protein response, its molecular mechanism and physiological impact

Bioengineering approaches in immunotherapy : from basic to translational applications

Quantitative Single-Cell Analysis of Host-Pathogen Interactions

Integrating Gene Synthesis and MITOMI for Rapid Protein Engineering

Unraveling the KRAB/KAP1 control of transposable elements in pluripotent and somatic cells

Protein engineering approaches for direct antigen targeting in CD8+ T cell inducing vaccines

Mechanical and Functional Study of Cell Physiology at the Nanoscale

Stem cell niche engineering through photopatterning and microfluidics

Allosteric regulation and targeting of Abl SH2-kinase interface and other cytoplasmic tyrosine kinases

Towards brain-on-a-chip : microfluidic and microelectrode array platforms for morphological and electrophysiological observations on the propagation of Alzheimer’s disease

In vivo mechanical loading combined with cell therapy in a bone tissue engineering scaffold

From the early steps of whisker formation to its evolutionary disappearance: the (curious) case of Prdm1 and its regulation

Engineering Lymphangiogenesis : Implications for Cancer Immunotherapy and Beyond

Microwell and impedance-based approaches to isolate single cells for life sciences

Microdevices for Locomotion in Complex Biological Fluids

Deciphering the Role of LRH-1 in Liver Intermediary Metabolism and Cancer

Nanoscopy in nonlinear scanning fluorescence imaging systems

Metabolic control of muscle and muscle stem cell function

Therapeutic Proteins Engineered for Super-Affinity to the Extracellular Matrix in Regenerative Medicine

Role of microRNAs in tumor-associated macrophages

Engineering nanoparticle-based vaccines: Implications for the quality of humoral and cellular immunity

Mechanisms of tolerance induction by erythrocyte-targeted antigens

Tunable and cell-responsive 3D poly(ethylene glycol) microenvironments for the development of tissue models

Engineering the Extra Domain A of fibronectin as a vaccine adjuvant and study of its role in tissue regeneration

Host and pathogen genomics of severe pediatric infections

New immunomodulatory roles of lymphatic endothelium and implications for immunotherapy

Protrusion-retraction switches and traction forces in spontaneous cell polarization

Instrumented shoes for daily activity monitoring in healthy and at risk populations

Novel interventions to recover the regenerative capacity of aged skeletal muscle by targeting the interactions in the stem cell niche

BCI based on Neural Correlates of Anticipatory Behavior during Driving

Quantification of low molecular weight drugs : from the selection of nucleic acid-based capture molecules to the characterization in patient samples

Deciphering Metabolic Regulation of Hematopoietic Stem Cell Fate

Reconstruction and systems analysis of metabolism in apicomplexan parasites Toxoplasma gondii and Plasmodium falciparum

Analytical Methods, Correlative Microscopy and Software Tools for Quantitative Single Molecule Localization Microscopy

Bioengineering approaches to emulate the stem cell niche

Connectivity Analysis of Brain States and Applications in Brain-Computer Interfaces

Study of transposon-mediated cell pool and cell line generation in CHO cells

Recapitulating De Novo Alpha-Synuclein Fibrillization in a Novel Neuronal Model of Parkinson’s Disease

Quantitative single-cell analysis of S. cerevisiae using a microfluidic live-cell imaging platform

Superresolution Reconstruction for Magnetic Resonance Spectroscopic Imaging Exploiting Low-Rank Spatio-Spectral Structure

Implementation and Characterization of Dynamic Genetic Networks in Vitro

Functional Perturbation of the Gab2 Multiprotein Complex by High-affinity SH2-binding Monobodies in Chronic Myelogenous Leukemia

Modeling and Engineering Proteins Thermostability

Bio-engineered collagen-fibrin scaffolds for enhancing urological tissue regeneration

Interactions of Peripheral Nerve Cells with Soft Micropillar Interfaces

Transposable elements and their KRAB/KAP1 controllers broadly regulate transcription in adult human cells

Microfluidic engineering of artificial stem cell niches

Tissue engineering for prenatal applications

Engineering adjuvants for prophylactic and therapeutic subunit vaccines

Experimental and theoretical studies on the effects of smooth muscle on the mechanical response and remodeling of arteries

Modeling of transcription mechanisms in mammals from kinetic measurements in single cells

An integrative genomics approach toward deciphering the regulatory logic of phase-specific circadian transcription in the mouse liver

Genetic analysis of the decaprenyl-phospho-D-arabinofuranose pathway in Mycobacterium tuberculosis

The Engineering of a Scalable Disposable Orbitally Shaken Bioreactor System for Animal Cell Cultivation and Therapeutic Protein Production

New Tools for Hydrogel-Based 3D Bioprinting

Thermal gradients on a chip for the local stimulation of biological systems

Subject-specific computational fluid dynamics modelling and measurement of cerebrospinal fluid motion in the cervical spine

From Genes to Organisms : Bioinformatics System Models and Software

Automated long-term single cell analysis of Schizosaccharomyces pombe on a microfluidic microchemostat array

The regulatory circuit of natural competence for transformation in the human pathogen Vibrio cholerae

Dynamic brain networks explored by structure-revealing methods

Dissecting the DNA binding principles of transcription factor monomers and heterodimers

Pharmacological and biochemical assessment of γ-secretase-mediated APP processing involved in Alzheimer’s disease

Reversible attachment of Cell-Penetrating Peptides for the efficient delivery of α-synuclein to HeLa cells and primary cortical neurons

Engineering the lymphatic microenvironment for investigating tumor invasion, immune cell traficking and parasite infection under relevant biomechanical conditions

A New Noninvasively Adjustable Glaucoma Drainage Device

Engineering lymphangiogenesis : methods, characterization and functional consequences

Label-free Analytics by Transmission Localized-SPR and its Application to Small Molecules Monitoring in Serum

Direct Somatic Cell Reprogramming in Synthetic 3D Microenvironments

Structure-function analysis of the EspR virulence regulator of Mycobacterium tuberculosis

Active Transport Mechanisms by Lymphatic Endothelium and their Modulation by Inflammatory Mediators

Novel non-invasive techniques for hemodynamic monitoring

Development of plasmid-based expression technology for rapid and sustained production of recombinant proteins in insect cells

The Effectual Hitchhiker : Mechanisms and Consequences of Interactions Between Endosymbiotic Spiroplasma and Host Drosophila

Development of a Bisphosphonate Delivering Hydrogel for the Augmentation of Impaired Peri-Implant Bone

A Systems Approach to Identify Genetic and Environmental Regulators of Metabolism

Tissue Engineering Bone by Matrix-Assisted MSC Recruitment

A systems approach to elucidate the genetic architecture of molecular phenotypes

In vitro Fate Mapping of Single Hematopoietic Stem Cells

Control of calcification in a biphasic osteochondral construct and enhancing interface integration

Development of Novel Nanoparticle-Based Vaccines and Immunotherapies : Tuberculosis, Lung Metastasis and Allergy as Models

Multiscale simulations of protein dynamics

Systematic Analysis of Yeast Gene Expression by Synthetic Promoter Libraries

Dissipation as variable in cartilage mechanobiology

The Use of Valproic Acid in Transient Gene Expression with HEK-293E Cells

Targeting and Modulating Tumor-Associated Sites with Novel Nanoparticle-Based Immunotherapies

Flexible Micro/Nanofabricated Systems for Medical Devices and Implants

Systems Biology of 3D Stem Cell-Niche Interactions

The Phosphate Specific Transport (Pst) System in Fast- and Slow-Growing Mycobacteria

Engineering nanoparticle vaccines : design principles for lymphatic targeting

Computational Studies on Cellular Bioenergetics

Molecular Modeling of Membrane Embedded Proteins

Epiphyseal Chondro-Progenitor Cell Therapy For Articular Cartilage Regeneration

Development and application of experimental tools to elucidate the gene regulatory network underlying adipogenesis

A Simple High Yielding Transient Gene Expression System for CHO Cells

Generating microarrays for protein interaction studies using microfluidic devices

Discovery and functional characterisation of structural genomic variation in a natural population

Temperature impacts human epidermal stem cell behaviour through thermoTRPs and mTOR signalling

Identification of genetic determinants and pharmacological modulators of mitochondrial function

Structure and function of proteins involved in attachment and piercing of the bacterial cell envelope

Role of the bile acid membrane receptor TGR5 in macrophages and metabolism

Metabolic modeling and experimental studies on carbon and energy metabolism of Mycobacterium tuberculosis

A microfluidic live-cell imaging platform to study large collections of microbial genotypes

Dissecting Gene Regulatory Networks Using Targeted Quantitative Proteomics

KRAB/KAP1 Regulation of Embryonic Stem Cell Pluripotent Self-renewal

Elucidating the role of post-translational modifications of alpha-synuclein using semisynthesis : phosphorylation at Tyrosine 125 and monoubiquitination at Lysine 6

Toxicity study of nanostructures

Immune Engineering Via Differential Antigen Carriers and Co-Stimulatory Molecules

Molecular and Functional Characterization of Clonogenic Human Thymic Epithelial Cells

Early Fate Choice Determines in vivo Engraftment and in vitro Behavior of Epidermal Stem Cells

Therapeutic Immunomodulation of the Lymphoid-like Tumor Environment Using Nanoparticulate Formulations

Multidisciplinary Analysis of the Metabolic Shift to Lactate Consumption in CHO Cell Culture

Single-Cell Analysis of Mycobacterial Persistence Using Microfabricated Tools

Microtechnologies to Map the Fate of Single Stem Cells and their Progeny

Photopatterning of Synthetic Hydrogels

Improving Immunogenicity of Subunit Vaccines Using Nanocarrier Systems

Genomics and transcriptomics of the Mycobacterium tuberculosis complex

Hydrogel Microfluidics to Control Stem Cell Fate

Nanopore sensing of single molecules application to RNAP-DNA complexes, fabrication of graphene-nanopore devices and translocation algorithm analysis

Molecular Modeling of Bacterial Nanomachineries

Structural Studies and Protein Engineering of Human O6-Alkylguanine-DNA Alkyltransferase

Culture and Characterization of Human and Porcine Urothelial Progenitor Cells

Biofunctional Scaffold Design for Soft Tissue Regeneration

On the Precision of Circadian Oscillators

The Role of LEKTI in the Fate Determination of Keratinocyte Stem Cells

New/Surface-Modified Biocompatible Polymer for ICD Lead Insulation

Studies on KRAB/KAP1-Mediated Transcriptional Repression

Engineering Erythrocyte Affinity for Improved Pharmacokinetics and Immune Tolerogenesis

Hydrogels for Urinary Tract Tissue Engineering

Identification and Functional Response of “Interstitial Cells of Cajal”-like Cells from Rat Mesenteric Artery

Force Transmission in Migrating Cells

Engineering of Signaling Microenvironments with Fibronectin Domains to Enhance Tissue Regeneration

Folding and Structure of the Pore Forming Toxin Aerolysin

Assessment of Body Motion and Muscle Weakness : Outcome Evaluation in Frail Elderly and DMD Subjects

Molecular Mechanisms Underlying Hyaline Fibromatosis Syndrome

In Vivo Studies on the Control of Gene Expression and Protein Degradation

Cellular Responses to Bacterial Pore-Forming Toxins

Pressure and Flow Wave Propagation in Patient-Specific Models of the Arterial Tree

In vitro lymphatic endothelial morphogenesis : molecular vs. biophysical regulation

OrbShake Bioreactors for Mammalian Cell Cultures : Engineering and Scale-up

The Interplay between Cytidine Deaminases, HIV and Domesticated Genetic Parasites

Small Molecule Based Approaches to Inhibit Macrophage Migration Inhibitory Factor (MIF) Activities and Elucidate its Role in Health and Disease

Biomechanics of Vascular Wall : the Role of Structural Organization of Elastin and Collagen

Ambulatory Assessment of Foot Kinematics and Kinetics : Outcome Evaluation of Ankle Osteoarthritis Treatments

Dendritic cell chemotaxis in 3D : new tools and insights

Rat bladder muscle regeneration induced by local delivery of an engineered insulin-like growth factor 1 in fibrin gels

Biophysical Regulation of Lymphatic Vessel Function : Flow as a Mediator of Immune Cell and Fluid Transport

Genomic Context and KRAB/KAP1-mediated Transcriptional Repression

Elucidating the Role of Quaternary Structure in Modulating Macrophage Migration Inhibitory Factor (MIF) Functions

Transient Gene Expression in HEK-293E Cells for Recombinant Protein Production : Process Characterization towards GMP Approval

Arterial remodeling using a constituent-based approach

Innate Barriers to Genome Invasion : how TRIM5a Restricts Retroelements

Identification of genetic insulator elements to increase the safety of viral gene therapy vectors

Lentiviral Vector-Mediated Gene Delivery for the Generation of Chinese Hamster Ovary Cell Lines with Improved Productivity and Stability

The role of TIF1 gamma during adult murine hematopoiesis

Immunoisolated cell implants for intracerebral delivery of anti-Aß single chain Fv antibodies in the APP23 Alzheimer’s mouse model

Stem cell-based cardiovascular tissue engineering

Studies on scaffold design for tissue engineering applications : contribution of synthetic, natural and recombinant materials

Orbitally shaken bioreactors for mammalian cell culture : engineering characterization and bioprocess scale-up

Peptide ligands for targeting and retention of nanoparticles and protein therapeutics in articular cartilage

Tissue engineering of the bladder : exploiting a 3D hydrogel for modulation of the smooth muscle cell phenotype

Protein-binding microarray technology and ChIP-sequencing for the identification of novel targets of the human tumor suppressor AP2[alpha]

The tissue reaction to neuroprostheses

Differential effects of reduced cyclic stretch and perturbed shear stress within the arterial wall

Transient recombinant protein expression in mammalian cells : the role of mRNA level and stability

Fetal cells for intervertebral disc regeneration

Investigation of novel calcium-related events as suspected contributors to neurodegeneration

The interplay between the VEGF-C/VEGFR-3 axis and CCL21/CCR7 axis in tumor cell invasion

Studies on lentiviral-mediated transgenesis

Exploiting immunofunctional nanoparticles as vaccines and synthetic pathogens

Molecular and mechanical regulators of lymphatic biology

Mechanical orchestration of tissue remodeling

Polymeric carriers for therapeutic agents : drug and gene delivery systems by reversible addition-fragmentation transfer (RAFT) polymerization

A novel cell culture approach for tissue engineering based on surface expansion

Effects of base-pair sequence, nicks and gaps on DNA minicircle shapes : analysis and experiment

Novel applications of poly(ethylene glycol)-bl-poly(propylene sulfide) block copolymers

Tissue engineering complex and mechanically active microenvironments for studies in asthma and cancer

Development of high-titer transient gene expression processes for manufacturing recombinant proteins

Vascular physiology : effects of vascular smooth muscle alteration on arterial wall biomechanics

Prevention of micromotion-related periprosthetic bone loss using local release of bisphosphonate : theoretical developments and experimental validations

Development of an in vitro microenvironment for maturing oocytes

Accelerating the development time of recombinant mammalian cell lines producing high titers of protein therapeutics

Role and mechanism of transient receptor potential (TRP) channels in gustatory and chemesthetic sensations associated with dietary molecules

Effects of dynamic environments on extracellular morphogen gradients

Bioreactor processes based on disposable materials for the production of recombinant proteins from mammalian cells

Polynucleotide cytidine deaminases, innate immunity and hepatitis B infection

Development of a novel drug delivery system based on polymeric, thermoresponsive, hydrogel nanoparticles