All cells arise by division. Failure to coordinate cell cycle events properly and execute them with high fidelity can lead to death of the progeny of a division event, or alterations of the genome which can contribute to the genesis of tumours. We use a simple model system to study how cell division (cytokinesis) is coordinated with chromosome segregation (mitosis). As these are mechanistically conserved processes, our findings should be applicable to understanding how division is controlled in human cells.
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