Publications

2021

C-C bond activation enabled by dyotropic rearrangement of Pd(iv) species

J. Cao; H. Wu; Q. Wang; J. Zhu 

Nature Chemistry

2021-05-24

DOI : 10.1038/s41557-021-00698-y

Visible light photoredox-catalysed remote C-H functionalisation enabled by 1,5-hydrogen atom transfer (1,5-HAT)

W. Guo; Q. Wang; J. Zhu 

Chemical Society Reviews

2021-05-20

DOI : 10.1039/d0cs00774a

Enantioselective Total Synthesis of (+)-Alstilobanine C, (+)-Undulifoline, and (-)-Alpneumine H

G. Li; N. Gaeng; C. Piemontesi; Q. Wang; J. Zhu 

Angewandte Chemie-International Edition

2021-04-23

DOI : 10.1002/anie.202103580

Selective 1,2-Aminoisothiocyanation of 1,3-Dienes Under Visible-Light Photoredox Catalysis

W. Guo; Q. Wang; J. Zhu 

Angewandte Chemie-International Edition

2021-02-12

Vol. 60 , num. 8, p. 4085-4089.

DOI : 10.1002/anie.202014518

Macrocyclization of omega-Isocyanoaldehydes and Towards the Total Synthesis of Jamaicensamide A

T. Songsichan / Director(s) : J. Zhu 

Lausanne: EPFL

2021

p. 153.

DOI : 10.5075/epfl-thesis-8714

Catalytic Enantioselective Synthesis of Morpholinones Enabled by Aza-Benzilic Ester Rearrangement

Y-P. He; H. Wu; Q. Wang; J. Zhu 

Journal of the American Chemical Society

2021

Vol. 143 , num. 19, p. 7320-7325.

DOI : 10.1021/jacs.1c03915

Iron-Catalysed Remote C(sp3)-H Azidation of O-Acyl Oximes and N -Acyloxy Imidates

A. Leclair; R. O. Torres-Ochoa; Q. Wang; J. Zhu 

CHIMIA International Journal for Chemistry

2021

Vol. 75 , num. 4, p. 329-332.

DOI : 10.2533/chimia.2021.329

Natural Product Synthesis Enabled by Domino Processes Incorporating a 1,2-Rearrangement Step

B. Delayre; Q. Wang; J. Zhu 

ACS Central Science

2021

Vol. 7 , num. 4, p. 559-569.

DOI : 10.1021/acscentsci.1c00075

Catalytic Enantioselective Aminopalladation–Heck Cascade

Y. He; J. Cao; H. Wu; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2021

Vol. 60 , num. 13, p. 7093-7097.

DOI : 10.1002/anie.202016001

Unified divergent strategy towards the total synthesis of the three sub-classes of hasubanan alkaloids

G. Li; Q. Wang; J. Zhu 

Nature Communications

2021

Vol. 12 , num. 36.

DOI : 10.1038/s41467-020-20274-1

2020

Radical-Cation Cascade to Aryltetralin Cyclic Ether Lignans Under Visible-Light Photoredox Catalysis

J-C. Xiang; Q. Wang; J. Zhu 

Angewandte Chemie-International Edition

2020-09-11

DOI : 10.1002/anie.202007548

Palladium-Catalyzed Multicomponent Synthesis of Fully Substituted Alkylidene Furanones

A. Renteria-Gomez; R. O. Torres-Ochoa; R. Gamez-Montano; Q. Wang; J. Zhu 

Organic Letters

2020-09-04

Vol. 22 , num. 17, p. 7030-7033.

DOI : 10.1021/acs.orglett.0c02578

Asymmetric Total Synthesis of (-)-Arborisidine and (-)-19-epi-Arborisidine Enabled by a Catalytic Enantioselective Pictet-Spengler Reaction

R. Andres; Q. Wang; J. Zhu 

Journal Of The American Chemical Society

2020-08-19

Vol. 142 , num. 33, p. 14276-14285.

DOI : 10.1021/jacs.0c05804

Synthesis of Benzo[a]carbazoles through Visible Light-Induced Cycloaromatization

B. Yao; Q. Wang; J. Zhu 

Helvetica Chimica Acta

2020-06-29

DOI : 10.1002/hlca.202000106

TiCl3-Mediated Synthesis of 2,3,3-Trisubstituted Indolenines: Total Synthesis of (+)-1,2-Dehydroaspidospermidine, (+)-Condyfoline, and (-)-Tubifoline

B. Delayre; C. Piemontesi; Q. Wang; J. Zhu 

Angewandte Chemie-International Edition

2020-06-04

DOI : 10.1002/anie.202005380

Copper-Catalyzed Cyanoalkylative Aziridination of N-Sulfonyl Allylamines

T. M. Ha; W. Guo; Q. Wang; J. Zhu 

Advanced Synthesis & Catalysis

2020-05-26

Vol. 362 , num. 11, p. 2205-2210.

DOI : 10.1002/adsc.202000276

Catalytic Enantioselective Benzilic Ester Rearrangement

H. Wu; Q. Wang; J. Zhu 

Angewandte Chemie-International Edition

2020-04-27

Vol. 59 , num. 18, p. 7261-7265.

DOI : 10.1002/anie.202001258

Towards the Sarpagine-Ajmaline-Macroline Family of Indole Alkaloids: Enantioselective Synthesis of an N-Demethyl Alstolactone Diastereomer

D. Dagoneau; Q. Wang; J. Zhu 

Chemistry-A European Journal

2020-03-25

DOI : 10.1002/chem.202000415

Construction of the Erythrinane Core Skeleton via Asymmetric Catalytic Cascade Reaction of Tertiary Enamides

L. Zhen; S. Tong; J. Zhu; M-X. Wang 

The Journal of Organic Chemistry

2020

Vol. 85 , num. 20, p. 13211-13219.

DOI : 10.1021/acs.joc.0c01992

Copper-Catalyzed 1,2-Methoxy Methoxycarbonylation of Alkenes with Methyl Formate and Synthetic Studies Towards the Total Synthesis of Koumine, Voacafricine A and Voacafricine B

B. Budai / Director(s) : J. Zhu 

Lausanne: EPFL

2020

p. 281.

DOI : 10.5075/epfl-thesis-10252

Catalytic Enantioselective Synthesis and Switchable Chiroptical Property of Inherently Chiral Macrocycles

S. Tong; J-T. Li; D-D. Liang; Y-Zhang; Q-Y. Feng et al. 

Journal of the American Chemical Society

2020

Vol. 142 , num. 34, p. 14432-14436.

DOI : 10.1021/jacs.0c05369

Palladium-Catalyzed Enantioselective Cacchi Reaction: Asymmetric Synthesis of Axially Chiral 2,3-Disubstituted Indoles

Y-P. He; H. Wu; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2020

Vol. 59 , num. 5, p. 2105-2109.

DOI : 10.1002/anie.201914049

Functionalization of remote C(sp3)-H bonds enabled by copper-catalyzed coupling of O-acyloximes with terminal alkynes

Z. Li; R. O. Torres-Ochoa; Q. Wang; J. Zhu 

Nature Communications

2020

Vol. 11 , num. 1.

DOI : 10.1038/s41467-020-14292-2

Fused N‐Heterocycles with Contiguous Stereogenic Centers Accessed by an Asymmetric Catalytic Cascade Reaction of Tertiary Enamides

L. Zhen; S. Tong; J. Zhu; M. Wang 

Chemistry – A European Journal

2020

Vol. 26 , num. 2, p. 401-405.

DOI : 10.1002/chem.201904596

Organocatalytic Double Ugi Reaction with Statistical Amplification of Product Enantiopurity: A Linker Cleavage Approach To Access Highly Enantiopure Ugi Products

Q-Y. Feng; J. Zhu; M-X. Wang; S. Tong 

Organic Letters

2020

Vol. 22 , num. 2, p. 483-487.

DOI : 10.1021/acs.orglett.9b04239

Desymmetrization of Prochiral Cyclopentenes Enabled by Enantioselective Palladium-Catalyzed Oxidative Heck Reaction

G. Chen; J. Cao; Q. Wang; J. Zhu 

Organic Letters

2020

Vol. 22 , num. 1, p. 322-325.

DOI : 10.1021/acs.orglett.9b04357

2019

Remote C(sp(3))-H Arylation and Vinylation of N-Alkoxypyridinium Salts to delta-Aryl and delta-Vinyl Alcohols

X. Bao; Q. Wang; J. Zhu 

Chemistry – A European Journal

2019-08-13

Vol. 25 , num. 50, p. 11630-11634.

DOI : 10.1002/chem.201902918

Total Synthesis of Alstolactine A & Synthetic Studies Towards Members of Akuammiline Alkaloids

R. Beltran / Director(s) : J. Zhu 

Lausanne: EPFL

2019

p. 213.

DOI : 10.5075/epfl-thesis-9817

Catalytic Enantioselective Pinacol and Meinwald Rearrangements for the Construction of Quaternary Stereocenters

H. Wu; Q. Wang; J. Zhu 

Journal of the American Chemical Society

2019

Vol. 141 , num. 29, p. 11372-11377.

DOI : 10.1021/jacs.9b04551

Copper-Catalyzed 1,2-Methoxy Methoxycarbonylation of Alkenes with Methyl Formate

B. Budai; A. Leclair; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2019

Vol. 58 , num. 30, p. 10305-10309.

DOI : 10.1002/anie.201904263

Catalytic Kinetic Resolution by Enantioselective Aromatization: Conversion of Racemic Intermediates of the Barton-Zard Reaction into Enantioenriched 3-Arylpyrroles

S-C. Zheng; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2019

Vol. 58 , num. 27, p. 9215-9219.

DOI : 10.1002/anie.201903589

Iron‐Catalysed Remote C(sp 3 )−H Azidation of O ‐Acyl Oximes and N ‐Acyloxy Imidates Enabled by 1,5‐Hydrogen Atom Transfer of Iminyl and Imidate Radicals: Synthesis of γ‐Azido Ketones and β‐Azido Alcohols

R. O. Torres‐Ochoa; A. Leclair; Q. Wang; J. Zhu 

Chemistry – A European Journal

2019

Vol. 25 , num. 40, p. 9477-9484.

DOI : 10.1002/chem.201901079

Formal [4+1] Cycloaddition of o ‐Aminobenzyl Chlorides with Isocyanides: Synthesis of 2‐Amino‐3‐Substituted Indoles

J. A. W. Jong; X. Bao; Q. Wang; J. Zhu 

Helvetica Chimica Acta

2019

Vol. 102 , num. 3, p. e1900002.

DOI : 10.1002/hlca.201900002

Palladium-Catalyzed Synthesis of Ketenimines from Isocyanides and Synthetic Studies Towards the Total Synthesis of Mersilongine

M. Mamboury / Director(s) : J. Zhu 

Lausanne: EPFL

2019

p. 218.

DOI : 10.5075/epfl-thesis-7176

Recent Advances in Catalytic Enantioselective Rearrangement

H. Wu; Q. Wang; J. Zhu 

European Journal of Organic Chemistry

2019

Vol. 2019 , num. 10, p. 1964-1980.

DOI : 10.1002/ejoc.201801799

Intramolecular Arylation of Tertiary Enamides through Pd(OAc)2-Catalyzed Dehydrogenative Cross-Coupling Reaction: Construction of Fused N-Heterocyclic Scaffolds and Synthesis of Isoindolobenzazepine Alkaloids

W. Zhu; S. Tong; J. Zhu; M-X. Wang 

The Journal of Organic Chemistry

2019

Vol. 84 , num. 5, p. 2870-2878.

DOI : 10.1021/acs.joc.9b00010

Copper-catalyzed remote C(sp3)–H azidation and oxidative trifluoromethylation of benzohydrazides

X. Bao; Q. Wang; J. Zhu 

Nature Communications

2019

Vol. 10 , num. 1, p. 769.

DOI : 10.1038/s41467-019-08741-w

Stereoselective Total Synthesis of Eburnane-Type Alkaloids Enabled by Conformation-Directed Cyclization and Rearrangement

G. Li; C. Piemontesi; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2019

Vol. 58 , num. 9, p. 2870-2874.

DOI : 10.1002/anie.201813920

Dual Photoredox/Copper Catalysis for the Remote C(sp3 )−H Functionalization of Alcohols and Alkyl Halides by N -Alkoxypyridinium Salts

X. Bao; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2019

Vol. 58 , num. 7, p. 2139-2143.

DOI : 10.1002/anie.201813356

Construction of Quaternary Stereocenters by Palladium-Catalyzed Carbopalladation-Initiated Cascade Reactions

Y. Ping; Y. Li; J. Zhu; W. Kong 

Angewandte Chemie International Edition

2019

Vol. 58 , num. 6, p. 1562-1573.

DOI : 10.1002/anie.201806088

Catalytic Atropenantioselective Heteroannulation between Isocyanoacetates and Alkynyl Ketones: Synthesis of Enantioenriched Axially Chiral 3-Arylpyrroles

S-C. Zheng; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2019

Vol. 58 , num. 5, p. 1494-1498.

DOI : 10.1002/anie.201812654

Catalytic Enantioselective α-Ketol Rearrangement

H. Wu; R. Andres; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2019

Vol. 58 , num. 2, p. 499-503.

DOI : 10.1002/anie.201812244

2018

From isonitrile to nitrile via ketenimine intermediate: Palladium-catalyzed 1,1-carbocyanation of ally carbonate by alpha-isocyanoacetate

G. Qiu; C. Sornay; D. Savary; S-C. Zheng; Q. Wang et al. 

Tetrahedron

2018-12-06

Vol. 74 , num. 49, p. 6966-6971.

DOI : 10.1016/j.tet.2018.10.032

Lewis acid catalyst-steered divergent synthesis of functionalized vicinal amino alcohols and pyrroles from tertiary enamides

X-M. Xu; C-H. Lei; S. Tong; J. Zhu; M-X. Wang 

Organic Chemistry Frontiers

2018-11-07

Vol. 5 , num. 21, p. 3138-3142.

DOI : 10.1039/c8qo00839f

Enantioselective total synthesis of (+)-Peganumine A

C. Piemontesi; Q. Wang; J. Zhu 

Abstracts Of Papers Of The American Chemical Society

2018-08-19

256th National Meeting and Exposition of the American-Chemical-Society (ACS) – Nanoscience, Nanotechnology and Beyond, Boston, MA, Aug 19-23, 2018.

Total Synthesis of Alstilobanine C, Undulifoline and Alstilobanine B

N. D. Gaeng / Director(s) : J. Zhu 

Lausanne: EPFL

2018

p. 264.

DOI : 10.5075/epfl-thesis-8983

Metamorphosis of cycloalkenes for the divergent total synthesis of polycyclic indole alkaloids

Z. Xu; Q. Wang; J. Zhu 

Chemical Society Reviews

2018

Vol. 47 , num. 21, p. 7882-7898.

DOI : 10.1039/C8CS00454D

Copper-catalyzed methylative difunctionalization of alkenes

X. Bao; T. Yokoe; T. M. Ha; Q. Wang; J. Zhu 

Nature Communications

2018

Vol. 9 , num. 1, p. 1995-1999.

DOI : 10.1038/s41467-018-06246-6

Chiral phosphoric acid-catalyzed enantioselective three-component Mannich reaction of acyclic ketones, aldehydes and anilines

S. Tong; Q. Wang; M-X. Wang; J. Zhu 

Tetrahedron

2018

Vol. 74 , num. 38, p. 5143-5149.

DOI : 10.1016/j.tet.2018.05.055

Copper-Catalyzed Arylation of Remote C(sp3 )−H Bonds in Carboxamides and Sulfonamides

Z. Li; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2018

Vol. 57 , num. 40, p. 13288-13292.

DOI : 10.1002/anie.201807623

Still Unconquered: Enantioselective Passerini and Ugi Multicomponent Reactions

Q. Wang; D-X. Wang; M-X. Wang; J. Zhu 

Accounts of Chemical Research

2018

Vol. 51 , num. 5, p. 1290-1300.

DOI : 10.1021/acs.accounts.8b00105

Heteroannulation of Arynes with α-Amino Imides: Synthesis of 2,2-Disubstituted Indolin-3-ones and Application to the Enantioselective Total Synthesis of (+)-Hinckdentine A

R. O. Torres-Ochoa; T. Buyck; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2018

Vol. 57 , num. 20, p. 5679-5683.

DOI : 10.1002/anie.201800746

Indole Alkaloids, Macrocycles and Heterocycles

C. Piemontesi / Director(s) : J. Zhu 

Lausanne: EPFL

2018

p. 627.

DOI : 10.5075/epfl-thesis-8477

Copper-Catalyzed Enantioselective Arylative Desymmetrization of Prochiral Cyclopentenes with Diaryliodonium Salts

H. Wu; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2018

Vol. 57 , num. 10, p. 2721-2725.

DOI : 10.1002/anie.201713329

Palladium-Catalyzed Enantioselective Desymmetrizing Aza-Wacker Reaction: Development and Application to the Total Synthesis of (−)-Mesembrane and (+)-Crinane

X. Bao; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2018

Vol. 57 , num. 7, p. 1995-1909.

DOI : 10.1002/anie.201712521

Cooperative Pd/Cu Catalysis: Multicomponent Synthesis of Tetrasubstituted Imidazolones from Methyl α-Isocyanoacetates, Primary Amines, and Aryl(vinyl) Iodides

A. Clemenceau; Q. Wang; J. Zhu 

Organic Letters

2018

Vol. 20 , num. 1, p. 126-129.

DOI : 10.1021/acs.orglett.7b03479

2017

“Divergent Total Synthesis of (-)-Rhazinilam, (-)-Leucomidine B and (+)-Leuconodine F” and “Synthetic Studies Towards Sarpagine-Related Indoles”

D. J. R. Dagoneau / Director(s) : J. Zhu 

EPFL

2017

p. 249.

DOI : 10.5075/epfl-thesis-8156

Catalytic Enantioselective Double Carbopalladation/C−H Functionalization with Statistical Amplification of Product Enantiopurity: A Convertible Linker Approach

S. Tong; A. Limouni; Q. Wang; M-X. Wang; J. Zhu 

Angewandte Chemie International Edition

2017

Vol. 56 , num. 45, p. 14192-14196.

DOI : 10.1002/anie.201709133

Copper-Catalyzed Enantioselective Domino Arylation/Semipinacol Rearrangement of Allylic Alcohols with Diaryliodonium Salts

H. Wu; Q. Wang; J. Zhu 

Chemistry – A European Journal

2017

Vol. 23 , num. 53, p. 13037-13041.

DOI : 10.1002/chem.201703563

Around isocyanide reactivity

A. F. R. Clemenceau / Director(s) : J. Zhu 

Lausanne: EPFL

2017

p. 278.

DOI : 10.5075/epfl-thesis-8153

Silver Nitrate-Catalyzed Isocyanide Insertion/Lactamization Sequence to Imidazolones and Quinazolin-4-ones: Development and Application in Natural Product Synthesis

A. Clemenceau; Q. Wang; J. Zhu 

Organic Letters

2017

Vol. 19 , num. 18, p. 4872-4875.

DOI : 10.1021/acs.orglett.7b02334

α-Oxo-Ketenimines from Isocyanides and α-Haloketones: Synthesis and Divergent Reactivity

M. Mamboury; Q. Wang; J. Zhu 

Chemistry – A European Journal

2017

Vol. 23 , num. 52, p. 12744-12748.

DOI : 10.1002/chem.201703458

Copper-Catalyzed Three-Component Carboazidation of Alkenes with Acetonitrile and Sodium Azide

A. Bunescu; T. M. Ha; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2017

Vol. 56 , num. 35, p. 10555-10558.

DOI : 10.1002/anie.201705353

Palladium-Catalyzed Enantioselective Narasaka-Heck Reaction/Direct C−H Alkylation of Arenes: Iminoarylation of Alkenes

X. Bao; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2017

Vol. 56 , num. 32, p. 9577-9581.

DOI : 10.1002/anie.201705641

Silver-Catalyzed Three-Component 1,1-Aminoacylation of Homopropargylamines: α-Additions for Both Terminal Alkynes and Isocyanides

S. Tong; C. Piemontesi; Q. Wang; M-X. Wang; J. Zhu 

Angewandte Chemie International Edition

2017

Vol. 56 , num. 27, p. 7958-7962.

DOI : 10.1002/anie.201704727

Fluorophores for Excited-State Intramolecular Proton Transfer by an Yttrium Triflate Catalyzed Reaction of Isocyanides with Thiocarboxylic Acids

S. Tong; S. Zhao; Q. He; Q. Wang; M-X. Wang et al. 

Angewandte Chemie International Edition

2017

Vol. 56 , num. 23, p. 6599-6603.

DOI : 10.1002/anie.201702488

Organocatalytic Enantioselective Acyloin Rearrangement of α-Hydroxy Acetals to α-Alkoxy Ketones

H. Wu; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2017

Vol. 56 , num. 21, p. 5858-5861.

DOI : 10.1002/anie.201701098

Organocatalytic Nucleophilic Addition of Hydrazones to Imines: Synthesis of Enantioenriched Vicinal Diamines

Y. Wang; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2017

Vol. 56 , num. 20, p. 5612-5615.

DOI : 10.1002/anie.201702295

Water as a Hydride Source in Palladium-Catalyzed Enantioselective Reductive Heck Reactions

W. Kong; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2017

Vol. 56 , num. 14, p. 3987-3991.

DOI : 10.1002/anie.201700195

To each his own: isonitriles for all flavors. Functionalized isocyanides as valuable tools in organic synthesis

M. Giustiniano; A. Basso; V. Mercalli; A. Massarotti; E. Novellino et al. 

Chemical Society Reviews

2017

Vol. 46 , num. 5, p. 1295-1357.

DOI : 10.1039/C6CS00444J

“Palladium-Catalyzed Diamination of Alkynes in Synthesis of Tetracycles” and “Copper-Catalyzed Cyanoalkylation of Unactivated Alkenes”

M. T. Ha / Director(s) : J. Zhu; Q. Wang 

Lausanne: EPFL

2017

p. 341.

DOI : 10.5075/epfl-thesis-7553

Palladium-Catalyzed Three-Component Reaction of Propargyl Carbonates, Isocyanides, and Alcohols or Water: Switchable Synthesis of Pyrroles and Its Bicyclic Analogues

G. Qiu; Q. Wang; J. Zhu 

Organic Letters

2017

Vol. 19 , num. 1, p. 270-273.

DOI : 10.1021/acs.orglett.6b03592

2016

Enantioselective Synthesis of Quaternary α-Amino Acids Enabled by the Versatility of the Phenylselenonyl Group

A. Clemenceau; Q. Wang; J. Zhu 

Chemistry – A European Journal

2016

Vol. 22 , num. 51, p. 18368-18372.

DOI : 10.1002/chem.201604781

Organocatalytic Enantioselective Vinylogous Pinacol Rearrangement Enabled by Chiral Ion Pairing

H. Wu; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2016

Vol. 55 , num. 49, p. 15411-15414.

DOI : 10.1002/anie.201609911

Ketenimines from Isocyanides and Allyl Carbonates: Palladium-Catalyzed Synthesis of β,γ-Unsaturated Amides and Tetrazoles

G. Qiu; M. Mamboury; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2016

Vol. 55 , num. 49, p. 15377-15381.

DOI : 10.1002/anie.201609034

Enantioselective Synthesis of (+)-Peganumine A

C. Piemontesi; Q. Wang; J. Zhu 

Journal of the American Chemical Society

2016

Vol. 138 , num. 35, p. 11148-11151.

DOI : 10.1021/jacs.6b07846

Copper-catalysed cyanoalkylative cycloetherification of alkenes to 1,3-dihydroisobenzofurans: development and application to the synthesis of citalopram

T. M. Ha; Q. Wang; J. Zhu 

Chemical Communications

2016

Vol. 52 , num. 74, p. 11100-11103.

DOI : 10.1039/C6CC06356J

Synthesis of Diversely Functionalized Oxindoles Enabled by Migratory Insertion of Isocyanide to a Transient σ-Alkylpalladium(II) Complex

W. Kong; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2016

Vol. 55 , num. 33, p. 9714-9718.

DOI : 10.1002/anie.201603950

Copper-Catalyzed Formal [2+2+1] Heteroannulation of Alkenes, Alkylnitriles, and Water: Method Development and Application to a Total Synthesis of (±)-Sacidumlignan D

T. M. Ha; C. Chatalova-Sazepin; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2016

Vol. 55 , num. 32, p. 9249-9252.

DOI : 10.1002/anie.201604528

Switchable [3+2] and [4+2] Heteroannulation of Primary Propargylamines with Isonitriles to Imidazoles and 1,6-Dihydropyrimidines: Catalyst Loading Enabled Reaction Divergence

S. Tong; Q. Wang; M-X. Wang; J. Zhu 

Chemistry – A European Journal

2016

Vol. 22 , num. 24, p. 8332-8338.

DOI : 10.1002/chem.201601560

Chiral Phosphoric Acid-Catalyzed Enantioselective Formal [3+2] Cycloaddition of Azomethine Imines with Enecarbamates

Y. Wang; Q. Wang; J. Zhu 

Chemistry – A European Journal

2016

Vol. 22 , num. 24, p. 8084-8088.

DOI : 10.1002/chem.201601548

Enantioselective Total Synthesis of (−)-Terengganensine A

C. Piemontesi; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2016

Vol. 55 , num. 22, p. 6556-6560.

DOI : 10.1002/anie.201602374

Chiral Phosphoric Acid Catalyzed Asymmetric Ugi Reaction by Dynamic Kinetic Resolution of the Primary Multicomponent Adduct

Y. Zhang; Y-F. Ao; Z-T. Huang; D-X. Wang; M-X. Wang et al. 

Angewandte Chemie International Edition

2016

Vol. 55 , num. 17, p. 5282-5285.

DOI : 10.1002/anie.201600751

Synthesis of Vinyl Isocyanides and Development of a Convertible Isonitrile

M. Spallarossa; Q. Wang; R. Riva; J. Zhu 

Organic Letters

2016

Vol. 18 , num. 7, p. 1622-1625.

DOI : 10.1021/acs.orglett.6b00483

Catalytic Asymmetric Tandem Reaction of Tertiary Enamides: Expeditious Synthesis of Pyrrolo[2,1-a]isoquinoline Alkaloid Derivatives

X-M. Xu; L. Zhao; J. Zhu; M-X. Wang 

Angewandte Chemie International Edition

2016

Vol. 55 , num. 11, p. 3799-3803.

DOI : 10.1002/anie.201600119

Total Synthesis of (±)-Strictamine

W. Ren; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2016

Vol. 55 , num. 10, p. 3500-3503.

DOI : 10.1002/anie.201511638

Synthesis of Oxazolidin-2-ones by Oxidative Coupling of Isonitriles, Phenyl Vinyl Selenone, and Water

T. Buyck; D. Pasche; Q. Wang; J. Zhu 

Chemistry – A European Journal

2016

Vol. 22 , num. 7, p. 2278-2281.

DOI : 10.1002/chem.201505050

Enantioselective Total Syntheses of (−)-Rhazinilam, (−)-Leucomidine B, and (+)-Leuconodine F

D. Dagoneau; Z. Xu; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2016

Vol. 55 , num. 2, p. 760-763.

DOI : 10.1002/anie.201508906

2015

Palladium-Catalyzed Enantioselective Domino Heck/Intermolecular C–H Bond Functionalization: Development and Application to the Synthesis of (+)-Esermethole

W. Kong; Q. Wang; J. Zhu 

Journal of the American Chemical Society

2015

Vol. 137 , num. 51, p. 16028-16031.

DOI : 10.1021/jacs.5b11625

An Enantioselective Total Synthesis of (−)-Isoschizogamine

Z. Xu; X. Bao; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2015

Vol. 54 , p. 14937-14940.

DOI : 10.1002/anie.201508150

Sulfonamide and Tertiary Amine as Nucleophiles in Pd(II)-Catalyzed Diamination of Alkynes: Synthesis of Tetracyclic Indolobenzothiazine S,S‑Dioxides

T. M. Ha; B. Yao; Q. Wang; J. Zhu 

Organic Letters

2015

Vol. 17 , num. 21, p. 5256-5259.

DOI : 10.1021/acs.orglett.5b02621

Aqueous Titanium Trichloride Promoted Reductive Cyclization of o-Nitrostyrenes to Indoles: Development and Application to the Synthesis of Rizatriptan and Aspidospermidine

S. Tong; Z. Xu; M. Mamboury; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2015

Vol. 54 , num. 40, p. 11809-11812.

DOI : 10.1002/anie.201505713

Synthesis of diverse di- to penta-substituted 1,2-dihydropyridine derivatives from gold(I)-catalyzed intramolecular addition of tertiary enamides to alkynes

X. Zhang; X-M. Xu; L. Zhao; J. You; J. Zhu et al. 

Tetrahedron Letters

2015

Vol. 56 , num. 25, p. 3898-3901.

DOI : 10.1016/j.tetlet.2015.04.105

Total Synthesis of Aspidosperma Family Indole Alkaloids through the iORC Domino Process

O. Wagnières / Director(s) : J. Zhu 

Lausanne: EPFL

2015

DOI : 10.5075/epfl-thesis-6607

Total Syntheses of (−)-Mersicarpine, (−)-Scholarisine G, (+)-Melodinine E, (−)-Leuconoxine, (−)-Leuconolam, (−)-Leuconodine A, (+)-Leuconodine F, and (−)-Leuconodine C: Self-Induced Diastereomeric Anisochronism (SIDA) Phenomenon for Scholarisine G and Leuconodines A and C

Z. Xu; Q. Wang; J. Zhu 

Journal of the American Chemical Society

2015

Vol. 137 , num. 20, p. 6712-6724.

DOI : 10.1021/jacs.5b03619

Synthesis of Functionalized Epoxides by Copper-Catalyzed Alkylative Epoxidation of Allylic Alcohols with Alkyl Nitriles

A. Bunescu; Q. Wang; J. Zhu 

Organic Letters

2015

Vol. 17 , num. 8, p. 1890-1893.

DOI : 10.1021/acs.orglett.5b00571

Pd/C-Catalyzed Cyclizative Cross-Coupling of Two ortho-Alkynylanilines under Aerobic Conditions: Synthesis of 2,3’-Bisindoles

B. Yao; Q. Wang; J. Zhu 

Chemistry – A European Journal

2015

Vol. 21 , num. 20, p. 7413-7416.

DOI : 10.1002/chem.201501020

Integrated One-Pot Synthesis of 1,3-Oxazinan-2-ones from Isocyanoacetates and Phenyl Vinyl Selenones

T. Buyck; Q. Wang; J. Zhu 

CHIMIA International Journal for Chemistry

2015

Vol. 69 , num. 4, p. 199-202.

DOI : 10.2533/chimia.2015.199

Copper-Catalyzed Intermolecular Carboetherification of Unactivated Alkenes by Alkyl Nitriles and Alcohols

C. Chatalova-Sazepin; Q. Wang; G. M. Sammis; J. Zhu 

Angewandte Chemie International Edition

2015

Vol. 54 , num. 18, p. 5443-5446.

DOI : 10.1002/anie.201412357

2-(Methoxycarbonyl)ethyl as a Removable N-Protecting Group: Synthesis of Indoloisoquinolinones by Pd(II)-Catalyzed Intramolecular Diamination of Alkynes

T. M. Ha; B. Yao; Q. Wang; J. Zhu 

Organic Letters

2015

Vol. 17 , num. 7, p. 1750-1753.

DOI : 10.1021/acs.orglett.5b00526

Copper-Catalyzed Cyanomethylation of Allylic Alcohols with Concomitant 1,2-Aryl Migration: Efficient Synthesis of Functionalized Ketones Containing an α-Quaternary Center

A. Bunescu; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2015

Vol. 54 , num. 10, p. 3132-3135.

DOI : 10.1002/anie.201411657

Enantioselective Synthesis of Putative Lipiarmycin Aglycon Related to Fidaxomicin/Tiacumicin B

W. Erb; J-M. Grassot; D. Linder; L. Neuville; J. Zhu 

Angewandte Chemie International Edition

2015

Vol. 54 , num. 6, p. 1929-1932.

DOI : 10.1002/anie.201409475

Multicomponent Reactions in Organic Synthesis

 

Weinheim, Germany: Wiley-VCH, 2015.

ISBN : 978-3-527-33237-3

Tuning the Reactivity of Isocyano Group: Synthesis of Imidazoles and Imidazoliums from Propargylamines and Isonitriles in the Presence of Multiple Catalysts

S. Tong; Q. Wang; M-X. Wang; J. Zhu 

Angewandte Chemie International Edition

2015

Vol. 54 , num. 4, p. 1293-1297.

DOI : 10.1002/anie.201410113

Chiral Calcium–BINOL Phosphate Catalyzed Diastereo- and Enantioselective Synthesis of syn-1,2-Disubstituted 1,2-Diamines: Scope and Mechanistic Studies

C. Lalli; A. Dumoulin; C. Lebée; F. Drouet; V. Guérineau et al. 

Chemistry – A European Journal

2015

Vol. 21 , num. 4, p. 1704-1712.

DOI : 10.1002/chem.201405286

Pd-Catalyzed Dehydrogenative Aryl−Aryl Bond Formation via Double C(sp2)−H Bond Activation: Efficient Synthesis of [3,4]-Fused Oxindoles

A. Bunescu; T. Piou; Q. Wang; J. Zhu 

Organic Letters

2015

Vol. 17 , num. 2, p. 334-337.

DOI : 10.1021/ol503442n

2014

Protecting-group-free enantioselective total synthesis of terengganensine A and towards the total synthesis of peganumine A

R. de Matos 

2014

Studies towards the total synthesis of strictamine

C. Piemontesi 

2014

Thiazoles enabled by discovering new reactivity of isonitriles: synthesis and fluorescence properties

S. Zhao 

2014

On the Formation and Transformation of alpha-Iminonitriles, the Desymmetrization of Bicyclic Bislactones and Total Synthesis of (-)-Leucomidine B and (-)-Rhazinilam

J-B. Gualtierotti / Director(s) : J. Zhu 

Lausanne: EPFL

2014

DOI : 10.5075/epfl-thesis-6489

Plastidic type I signal peptidase 1 is a redox-dependent thylakoidal processing peptidase

T. Midorikawa; J. K. Endow; J. Dufour; J. Zhu; K. Inoue 

Plant Journal

2014

Vol. 80 , num. 4, p. 592-603.

DOI : 10.1111/tpj.12655

Isocyanoacetates as Synthetic Platform Towards Natural Products and Biologically Relevant Scaffolds

T. Buyck / Director(s) : J. Zhu 

Lausanne: EPFL

2014

DOI : 10.5075/epfl-thesis-6448

“New methods for indoles and [3,4]-fused oxindoles syntheses” and “Copper-catalyzed/mediated difunctionalization of alkenes with alkylnitriles”

A. Bunescu / Director(s) : J. Zhu 

Lausanne: EPFL

2014

DOI : 10.5075/epfl-thesis-6453

Copper-Mediated/Catalyzed Oxyalkylation of Alkenes with Alkylnitriles

A. Bunescu; Q. Wang; J. Zhu 

Chemistry – A European Journal

2014

Vol. 20 , num. 45, p. 14633-14636.

DOI : 10.1002/chem.201405102

Unified Strategy to Monoterpene Indole Alkaloids: Total Syntheses of (±)-Goniomitine, (±)-1,2-Dehydroaspidospermidine, (±)-Aspidospermidine, (±)-Vincadifformine, and (±)-Kopsihainanine A

O. Wagnières; Z. Xu; Q. Wang; J. Zhu 

Journal of the American Chemical Society

2014

Vol. 136 , num. 42, p. 15102-15108.

DOI : 10.1021/ja509329x

Functionalized imidazoliniums from the three-component domino reaction of N-formylmethylcarboxamides with amines and isocyanides

C-H. Lei; L. Zhao; D-X. Wang; J. Zhu; M-X. Wang 

Organic Chemistry Frontiers

2014

Vol. 1 , num. 8, p. 909-913.

DOI : 10.1039/C4QO00203B

Mechanistic Study on the Palladium(II)-Catalyzed Synthesis of 2,3-Disubstituted Indoles Under Aerobic Conditions: Anion Effects and the Development of a Low-Catalyst-Loading Process

B. Yao; Q. Wang; J. Zhu 

Chemistry – A European Journal

2014

Vol. 20 , p. 12255-12261.

DOI : 10.1002/chem.201403612

Phosphoric Acid Catalyzed Desymmetrization of Bicyclic Bislactones Bearing an All-Carbon Stereogenic Center: Total Syntheses of (−)-Rhazinilam and (−)-Leucomidine B

J-B. Gualtierotti; D. Pasche; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2014

Vol. 53 , num. 37, p. 9926-9930.

DOI : 10.1002/anie.201405842

Triple Role of Phenylselenonyl Group Enabled a One-Pot Synthesis of 1,3-Oxazinan-2-ones From α-Isocyanoacetates, Phenyl Vinyl Selenones, and Water

T. Buyck; Q. Wang; J. Zhu 

Journal of the American Chemical Society

2014

Vol. 136 , num. 32, p. 11524-11528.

DOI : 10.1021/ja506031h

Chiral Phosphoric Acid-Catalyzed Enantioselective Three- Component Aza-Diels-Alder Reactions of Aminopyrroles and Aminopyrazoles

J. Brioche; T. Courant; L. Alcaraz; M. Stocks; M. Furber et al. 

Advanced Synthesis & Catalysis

2014

Vol. 356 , num. 8, p. 1719-1724.

DOI : 10.1002/adsc.201400093

From Racemic to Enantioselective Total Synthesis of Trigonoliimines via Development of an Organocatalytic Enantioselective Michael Addition of α-Aryl-α-isocyanoacetate to Vinyl Phenyl Selenone

T. Buyck; Q. Wang; J. Zhu 

CHIMIA International Journal for Chemistry

2014

Vol. 68 , num. 4, p. 211-214.

DOI : 10.2533/chimia.2014.211

Phosphoric Acid Catalyzed Diastereo- and Enantioselective Synthesis of Substituted 1,3-Diaminotetralins

G. Dagousset; W. Erb; J. Zhu; G. Masson 

Organic Letters

2014

Vol. 16 , num. 9, p. 2554-2557.

DOI : 10.1021/ol500946w

Copper-catalyzed three-component synthesis of 5-acetamidoimidazoles from carbodiimides, acyl chlorides and isocyanides

G. Sapuppo; Q. Wang; D. Swinnen; J. Zhu 

Organic Chemistry Frontiers

2014

Vol. 1 , num. 3, p. 240.

DOI : 10.1039/c4qo00034j

Three-Component Povarov Reaction–Heteroannulation with Arynes: Synthesis of 5,6-Dihydroindolo[1,2‑a]quinolines

A. Bunescu; Q. Wang; J. Zhu 

Organic Letters

2014

Vol. 16 , num. 6, p. 1756-1759.

DOI : 10.1021/ol500447r

Multicomponent Domino Process: Rational Design and Serendipity

Q. Wang; J. Zhu 

Domino Reactions: Concepts for Efficient Organic Synthesis; Weinheim: Wiley-VCH, 2014. p. 579-610.

ISBN : 978-3-527-33432-2

DOI : 10.1002/9783527671304.ch15

NIS-Assisted Aza-Friedel-Crafts Reaction with α-Carbamoysulfides as Precursors of

N. George; M. Bekkaye; A. Alix; J. Zhu; G. Masson 

Chemistry – A European Journal

2014

Vol. 20 , num. 13, p. 3621-3625.

DOI : 10.1002/chem.201400117

Total Synthesis of (±)-Aspidophylline A

W. Ren; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2014

Vol. 53 , num. 7, p. 1818-1821.

DOI : 10.1002/anie.201310929

2013

Design and Synthesis of 16-Membered Cyclopeptides Active Against Vancomycin-resistant Enterococci (VRE)

J. Zhu 

CHIMIA International Journal for Chemistry

2013

Vol. 67 , num. 12, p. 916-920.

DOI : 10.2533/chimia.2013.916

Enantioselective Total Syntheses of Leuconolam–Leuconoxine–Mersicarpine Group Monoterpene Indole Alkaloids

Z. Xu; Q. Wang; J. Zhu 

Journal of the American Chemical Society

2013

Vol. 135 , num. 51, p. 19127-19130.

DOI : 10.1021/ja4115192

Iron Chloride-Catalyzed Three-Component Domino Sequences: Syntheses of Functionalized α-Oxy-N-acylhemiaminals and α-Oxyimides

F. Drouet; J. Zhu; G. Masson 

Advanced Synthesis & Catalysis

2013

Vol. 355 , num. 18, p. 3563-3569.

DOI : 10.1002/adsc.201300847

Palladium(II)-Catalyzed Cyclizative Cross-Coupling of ortho-Alkynylanilines with ortho-Alkynylbenzamides under Aerobic Conditions

B. Yao; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2013

Vol. 52 , num. 49, p. 12992-12996.

DOI : 10.1002/anie.201307738

Synthesis of Multifunctionalized 1,2,3,4-Tetrahydropyridines, 2,3-Dihydropyridin-4(1H)-ones, and Pyridines from Tandem Reactions Initiated by [5+1] Cycloaddition of N-Formylmethyl-Substituted Enamides to Isocyanides: Mechanistic Insight and Synthetic Application

C-H. Lei; D-X. Wang; L. Zhao; J. Zhu; M-X. Wang 

Chemistry – A European Journal

2013

Vol. 19 , num. 50, p. 16981-16987.

DOI : 10.1002/chem.201303221

Catalytic Enantioselective Michael Addition of α-Aryl-α-Isocyanoacetates to Vinyl Selenone: Synthesis of α,α-Disubstituted α-Amino Acids and (+)- and (−)-Trigonoliimine A

T. Buyck; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2013

Vol. 52 , num. 48, p. 12714-12718.

DOI : 10.1002/anie.201306663

Palladium-Catalyzed Through-Space C(sp3)-H and C(sp2)-H Bond Activation by 1,4-Palladium Migration: Efficient Synthesis of [3,4]- Fused Oxindoles

T. Piou; A. Bunescu; Q. Wang; L. Neuville; J. Zhu 

Angewandte Chemie International Edition

2013

Vol. 52 , num. 47, p. 12385-12389.

DOI : 10.1002/anie.201306532

Heteroannulation of arynes with N-aryl-α-aminoketones for the synthesis of unsymmetrical N-aryl-2,3-disubstituted indoles: an aryne twist of Bischler–Möhlau indole synthesis

A. Bunescu; C. Piemontesi; Q. Wang; J. Zhu 

Chemical Communications

2013

Vol. 49 , num. 87, p. 10284.

DOI : 10.1039/c3cc46361c

Zinc Bromide Promoted Coupling of Isonitriles with Carboxylic Acids To Form 2,4,5-Trisubstituted Oxazoles

Y. Odabachian; S. Tong; Q. Wang; M-X. Wang; J. Zhu 

Angewandte Chemie International Edition

2013

Vol. 52 , num. 41, p. 10878-10882.

DOI : 10.1002/anie.201305506

Tertiary Amines as Synthetic Equivalents of Vinyl Cations: Zinc Bromide Promoted Coupling of Propargylamines with α-Isocyanoacetamides To Give 2,4,5-Trisubstituted Oxazoles Initiated by an Internal Redox Process

Y. Odabachian; Q. Wang; J. Zhu 

Chemistry – A European Journal

2013

Vol. 19 , num. 37, p. 12229-12233.

DOI : 10.1002/chem.201302106

Synthetic Study towards Strictamine: The Oxidative Coupling Approach

W. Ren; N. Tappin; Q. Wang; J. Zhu 

Synlett

2013

Vol. 24 , p. 1941-1944.

DOI : 10.1055/s-0033-1339472

Ugi Four-Component Reaction of Alcohols: Stoichiometric and Catalytic Oxidation/MCR Sequences

F. Drouet; G. Masson; J. Zhu 

Organic Letters

2013

Vol. 15 , num. 11, p. 2854-2857.

DOI : 10.1021/ol401181a

Synthesis of Iminonitriles by Oxone/TBAB-Mediated One-Pot Oxidative Three-Component Strecker Reaction

J-B. Gualtierotti; X. Schumacher; Q. Wang; J. Zhu 

Synthesis

2013

Vol. 45 , num. 10, p. 1380-1386.

DOI : 10.1055/s-0032-1316908

Pd(II)-catalyzed intramolecular aminopalladation/direct C–H arylation under aerobic conditions: synthesis of pyrrolo[1,2-a]indoles

T. Piou; L. Neuville; J. Zhu 

Tetrahedron

2013

Vol. 69 , num. 22, p. 4415-4420.

DOI : 10.1016/j.tet.2013.01.003

Synthesis of Substituted Pyridines from Cascade [1 + 5] Cycloaddition of Isonitriles to

C-H. Lei; D-X. Wang; L. Zhao; J. Zhu; M-X. Wang 

Journal of the American Chemical Society

2013

Vol. 135 , num. 12, p. 4708-4711.

DOI : 10.1021/ja401701x

Palladium-Catalyzed Decarboxylative Vinylation of Potassium Nitrophenyl Acetate: Application to the Total Synthesis of (±)-Goniomitine

Z. Xu; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2013

Vol. 52 , num. 11, p. 3272-3276.

DOI : 10.1002/anie.201209970

Synthesis of 3,3-disubstituted oxindoles by one-pot integrated Brønsted base-catalyzed trichloroacetimidation of 3-hydroxyoxindoles and Brønsted acid-catalyzed nucleophilic substitution reaction

C. Piemontesi; Q. Wang; J. Zhu 

Organic & Biomolecular Chemistry

2013

Vol. 11 , num. 9, p. 1533.

DOI : 10.1039/c2ob27196f

From natural product to marketed drug: the tiacumicin odyssey

W. Erb; J. Zhu 

Natural Product Reports

2013

Vol. 30 , num. 1, p. 161.

DOI : 10.1039/c2np20080e

2012

Enantioselctive Passerini Reaction

Q. Wang; J. Zhu; M. X. Wang 

Asymmetric Synthesis – The Essentials II; Weinheim: Wiley-VCH, 2012. p. 95-102.

ISBN : 978-3-527-32921-2

DOI : 10.1002/9783527652235.ch13

Total Synthesis of Natural Products and the Synergy with Synthetic Methodology

Q. Wang; J. Zhu 

Organic Chemistry-Breakthroughs and Perspectives; Weinheim: Wiley-VCH, 2012. p. 33-79.

ISBN : 978-3-527-33377-6

DOI : 10.1002/9783527664801.ch2

Copper Catalyzed N-Arylation of Amidines with Aryl Boronic Acids and One-Pot Synthesis of Benzimidazoles by a Chan–Lam–Evans N-Arylation and C–H Activation/C–N Bond Forming Process

J. Li; S. Bénard; L. Neuville; J. Zhu 

Organic Letters

2012

Vol. 14 , num. 23, p. 5980-5983.

DOI : 10.1021/ol3028847

Synthesis of Indoles by Copper-Catalyzed Heteroannulation of o-Aminophenylboronic Acid Pinacol Esters with β-Keto Esters

A. Bunescu; Q. Wang; J. Zhu 

Synthesis

2012

Vol. 44 , num. 24, p. 3811-3814.

DOI : 10.1055/s-0032-1316813

Palladium-Catalyzed Coupling of ortho-Alkynylanilines with Terminal Alkynes Under Aerobic Conditions: Efficient Synthesis of 2,3-Disubstituted 3-Alkynylindoles

B. Yao; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2012

Vol. 51 , num. 49, p. 12311-12315.

DOI : 10.1002/anie.201205596

Activation of a C(sp3)H Bond by a Transient s-Alkylpalladium(II) Complex: Synthesis of Spirooxindoles Through a Palladium-Catalyzed Domino Carbopalladation/C(sp3)C(sp3) Bond-Forming Process

T. Piou; L. Neuville; J. Zhu 

Angewandte Chemie International Edition

2012

Vol. 51 , num. 46, p. 11561-11565.

DOI : 10.1002/anie.201206267

Amidation of Aldehydes and Alcohols through α-Iminonitriles and a Sequential Oxidative Three-Component Strecker Reaction/Thio-Michael Addition/Alumina-Promoted Hydrolysis Process to Access β-Mercaptoamides from Aldehydes, Amines, and Thiols

J-B. Gualtierotti; X. Schumacher; P. Fontaine; G. Masson; Q. Wang et al. 

Chemistry – A European Journal

2012

Vol. 18 , num. 46, p. 14812-14819.

DOI : 10.1002/chem.201202291

Organocatalytic Enantioselective One-Pot Four-Component Ugi-Type Multicomponent Reaction for the Synthesis of Epoxy-tetrahydropyrrolo[3,4-

Y. Su; M. J. Bouma; L. Alcaraz; M. Stocks; M. Furber et al. 

Chemistry – A European Journal

2012

Vol. 18 , num. 40, p. 12624-12627.

DOI : 10.1002/chem.201202174

Synthesis of 4-amino-1,2,3,4-tetrahydropyridine derivatives by intramolecular nucleophilic addition of tertiary enamides to in-situ generated imines

S. Tong; X. Yang; D-X. Wang; L. Zhao; J. Zhu et al. 

Tetrahedron

2012

Vol. 68 , num. 32, p. 6492-6497.

DOI : 10.1016/j.tet.2012.05.108

Spirocyclization by Palladium-Catalyzed Domino Heck–Direct C–H Arylation Reactions: Synthesis of Spirodihydroquinolin-2-ones

T. Piou; L. Neuville; J. Zhu 

Organic Letters

2012

Vol. 14 , num. 14, p. 3760-3763.

DOI : 10.1021/ol301616w

Development and Application of Isocyanide-based Multicomponent Reactions

J. Zhu; Q. Wang; M-X. Wang 

Green Synthesis; Weinheim: WIley-VCH, 2012. p. 121-157.

ISBN : 978-3-527-32602-0

DOI : 10.1002/9783527628698.hgc076

Palladium(II)-Catalyzed Intramolecular Diamination of Alkynes under Aerobic Oxidative Conditions: Catalytic Turnover of an Iodide Ion

B. Yao; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2012

Vol. 51 , num. 21, p. 5170-5174.

DOI : 10.1002/anie.201201640

Enantioselective Synthesis of 4-Hydroxytetrahydropyridine Derivatives by Intramolecular Addition of Tertiary Enamides to Aldehydes

S. Tong; D-X. Wang; L. Zhao; J. Zhu; M-X. Wang 

Angewandte Chemie International Edition

2012

Vol. 51 , num. 18, p. 4417-4420.

DOI : 10.1002/anie.201200459

Synergistic Effect of Palladium and Copper Catalysts: Catalytic Cyclizative Dimerization of ortho-(1-Alkynyl)benzamides Leading to Axially Chiral 1,3-Butadienes

B. Yao; C. Jaccoud; Q. Wang; J. Zhu 

Chemistry – A European Journal

2012

Vol. 18 , num. 19, p. 5864-5868.

DOI : 10.1002/chem.201200215

Chiral Phosphoric Acid-Catalyzed Enantioselective Three-Component Povarov Reaction Using Cyclic Enethioureas as Dienophiles: Stereocontrolled Access to Enantioenriched Hexahydropyrroloquinolines

G. Dagousset; P. Retailleau; G. Masson; J. Zhu 

Chemistry – A European Journal

2012

Vol. 18 , num. 19, p. 5869-5873.

DOI : 10.1002/chem.201200523

A Concise Total Synthesis of (±)-Trigonoliimine B

T. Buyck; Q. Wang; J. Zhu 

Organic Letters

2012

Vol. 14 , num. 5, p. 1338-1341.

DOI : 10.1021/ol300249y

Un nouveau venu dans la lutte contre le Clostridium difficile: Les antibiotiques accueillent un nouveau membre

W. Erb; J. Zhu 

L’Actualité Chimique

2012

num. 360-361, p. 83-89.

Exploiting the Divergent Reactivity of Isocyanoacetates: One-Pot Three-Component Synthesis of Functionalized Angular Furoquinolines

M. J. Bouma; G. Masson; J. Zhu 

European Journal Of Organic Chemistry

2012

p. 475-479.

DOI : 10.1002/ejoc.201101567

2011

Unexpected C–C Bond Cleavage: Synthesis of 1,2,4-Oxadiazol-5-ones from Amidoximes with Pentafluorophenyl or Trifluoromethyl Anion Acting as Leaving Group

T. Gerfaud; H-L. Wei; L. Neuville; J. Zhu 

Organic Letters

2011

Vol. 13 , num. 23, p. 6172-6175.

DOI : 10.1021/ol202554m

Trifluoroacetic Acid-Promoted Synthesis of 3-Hydroxy, 3-Amino and Spirooxindoles from α-Keto-N-Anilides

I. Gorokhovik; L. Neuville; J. Zhu 

Organic Letters

2011

Vol. 13 , num. 20, p. 5536-5539.

DOI : 10.1021/ol202263a

Built-in 5-Aminooxazole as an Internal Activator of the Terminal Carboxylic Acid: An Alternative Access to Macrocyclodepsipeptides

J. Zhu 

CHIMIA International Journal for Chemistry

2011

Vol. 65 , num. 9, p. 710-714.

DOI : 10.2533/chimia.2011.710

Chiral Phosphoric Acid-Catalyzed Enantioselective Three-Component Povarov Reaction Using Enecarbamates as Dienophiles: Highly Diastereo- and Enantioselective Synthesis of Substituted 4-Aminotetrahydroquinolines

G. Dagousset; J. Zhu; G. Masson 

Journal of the American Chemical Society

2011

Vol. 133 , num. 37, p. 14804-14813.

DOI : 10.1021/ja205891m

A Practical, One-Pot Multicomponent Synthesis of α-Amidosulfides and Their Application as Latent N-Acylimines in the Friedel-Crafts Reaction

N. George; M. Bekkaye; G. Masson; J. Zhu 

European Journal of Organic Chemistry

2011

Vol. 2011 , num. 20-21, p. 3695-3699.

DOI : 10.1002/ejoc.201100426

Cinchona Alkaloid-Amides Catalyzed Enantioselective Formal [2+2] Cycloadditions of Allenoates and Imines: Enantioselective Synthesis of 2,4-Substituted Azetidines

J-B. Denis; G. Masson; P. Retailleau; J. Zhu 

Angewandte Chemie -International Edition in English-

2011

Vol. 50 , num. 23, p. 5356-5360.

DOI : 10.1002/anie.201100706

Protecting-Group-Free Total Synthesis of (E) and (Z)-Alstoscholarine

T. Gerfaud; C. Xie; L. Neuville; J. Zhu 

Angewandte Chemie -International Edition in English-

2011

Vol. 50 , num. 17, p. 3954-3957.

DOI : 10.1002/anie.201100257

Iodo-Carbocyclization of Electron-Deficient Alkenes: Synthesis of Oxindoles and Spirooxindoles

H-L. Wei; T. Piou; J. Dufour; L. Neuville; J. Zhu 

Organic Letters

2011

Vol. 13 , num. 9, p. 2244-2247.

DOI : 10.1021/ol2005243

Synthesis of Hydroxylated 3,4-Dihydropyridine-2-ones from Intramolecular Nucleophilic Addition Reaction of Oxirane-containing Tertiary Enamides

L. Yang; S. Tong; D-X. Wang; Z-T. Huang; J. Zhu et al. 

Synlett

2011

num. 7, p. 927-930.

DOI : 10.1055/s-0030-1259703

Asymmetric Synthesis of 2,4,6-Trideoxy-4-(dimethylamino)-3-C-methyl-Llyxohexopyranose (Lemonose)

G. Bernadat; N. George; C. Couturier; G. Masson; T. Schlama et al. 

Synlett

2011

num. 4, p. 576-578.

DOI : 10.1055/s-0030-1259531

Access to Macrocycles with an endo Aryl ether and an endo Aryl-Aryl Bond, Development and Application

Q. Wang; J. Zhu 

Chimia

2011

Vol. 65 , num. 3, p. 168-174.

DOI : 10.2533/chimia.2011.168

Exploiting the Divergent Reactivity of a-Isocyanoacetate: Multicomponent Synthesis of 5-Alkoxyoxazoles and Related Heterocycles

C. Lalli; M. J. Bouma; D. Bonne; G. Masson; J. Zhu 

Chemistry-A European Journal

2011

Vol. 17 , num. 3, p. 881-889.

DOI : 10.1002/chem.201002098

Chiral Calcium Organophosphate-Catalyzed Enantioselective Electrophilic Amination of Enamides

F. Drouet; C. Lalli; H. Liu; G. Masson; J. Zhu 

Organic Letters

2011

Vol. 13 , num. 1, p. 94-97.

DOI : 10.1021/ol102625s

2010

Asymmetric Morita–Baylis–Hillman Reaction and Its Aza Analogue

G. Masson; J. Zhu 

Stereoselective synthesis 2: Stereoselective reactions of carbonyl and imino groups; Stuttgart, New York: Georg Thieme Verlag, 2010. p. 735-784.

ISBN : 978-3-13-154121-5

1-Isocyanocyclohex-1-ene

D. Linder; J. Zhu 

e-EROS Encyclopedia of Reagents for Organic Synthesis; 2010.

DOI : 10.1002/047084289X.rn01168

1-Isocyano-2-nitrobenzene

D. Linder; J. Zhu 

e-EROS Encyclopedia of Reagents for Organic Synthesis; 2010.

DOI : 10.1002/047084289X.rn01165

1-(2,2-Dimethoxyethyl)-2-isocyanobenzene

D. Linder; J. Zhu 

e-EROS Encyclopedia of Reagents for Organic Synthesis

2010

DOI : 10.1002/047084289X.rn01163

Multicomponent Syntheses of Macrocycles

G. Masson; L. Neuville; C. Burghin; A. Fayol; J. Zhu 

Synthesis of Heterocycles via Multicomponent Reactions II; Berlin: Springer, 2010. p. 1-24.

DOI : 10.1007/7081_2010_47

Enantioselective Aza-Morita-Baylis-Hillman Reaction Using Aliphatic alpha -Amidosulfones as Imine Surrogates

N. Abermil; G. Masson; J. Zhu 

Advanced Synthesis & Catalysis

2010

Vol. 352 , num. 4, p. 656-660.

DOI : 10.1002/adsc.200900900

Copper-promoted N-cyclopropylation of anilines and amines by cyclopropylboronic acid

S. Benard; L. Neuville; J. Zhu 

Chemical Communications

2010

Vol. 46 , num. 19, p. 3393-3395.

DOI : 10.1039/b925499d

Zinc Chloride Promoted Formal Oxidative Coupling of Aromatic Aldehydes and Isocyanides to alpha -Ketoamides

M. Bouma; G. Masson; J. Zhu 

Journal of Organic Chemistry

2010

Vol. 75 , num. 8, p. 2748-2751.

DOI : 10.1021/jo100302y

Passerini Three-Component Reaction of Alcohols under Catalytic Aerobic Oxidative Conditions

J. Brioche; G. Masson; J. Zhu 

Organic Letters

2010

Vol. 12 , num. 7, p. 1432-1435.

DOI : 10.1021/ol100012y

Intramolecular Suzuki-Miyaura reaction for the total synthesis of signal peptidase inhibitors, arylomycins A2 and B2

J. Dufour; L. Neuville; J. Zhu 

Chemistry–A European Journal

2010

Vol. 16 , num. 34, p. 10523-10534, S10523/1-S10523/76.

DOI : 10.1002/chem.201000924

Palladium-catalyzed domino Heck/cyanation: synthesis of 3-cyanomethyloxindoles and their conversion to spirooxoindoles

S. Jaegli; J-P. Vors; L. Neuville; J. Zhu 

Tetrahedron

2010

Vol. 66 , num. 46, p. 8911-8921.

DOI : 10.1016/j.tet.2010.09.056

Palladium-Catalyzed Carbo-Heterofunctionalization of Alkenes for the Synthesis of Oxindoles and Spirooxindoles

S. Jaegli; J. Dufour; H-l. Wei; T. Piou; X-H. Duan et al. 

Organic Letters

2010

Vol. 12 , num. 20, p. 4498-4501.

DOI : 10.1021/ol101778c

Palladium-Catalyzed Domino Process to Spirooxindoles: Ligand Effect on Aminopalladation versus Carbopalladation

S. Jaegli; W. Erb; P. Retailleau; J-P. Vors; L. Neuville et al. 

Chemistry–A European Journal

2010

Vol. 16 , num. 20, p. 5863-5867, S5863/1-S5863/38.

DOI : 10.1002/chem.201000312

Efficient Synthesis of alpha -Ketoamides via 2-Acyl-5-aminooxazoles by Reacting Acyl Chlorides and alpha -Isocyanoacetamides

R. Mossetti; T. Pirali; G. C. Tron; J. Zhu 

Organic Letters

2010

Vol. 12 , num. 4, p. 820-823.

DOI : 10.1021/ol902894p

Total synthesis of complestatin (Chloropeptin II)

Z. Wang; M. Bois-Choussy; Y. Jia; J. Zhu 

Angewandte Chemie, International Edition

2010

Vol. 49 , num. 11, p. 2018-2022, S2018/1-S2018/23.

DOI : 10.1002/anie.200906797

2009

Invertible Enantioselectivity in 6′-Deoxy-6′-acylamino-beta -isocupreidine-Catalyzed Asymmetric Aza-Morita-Baylis-Hillman Reaction: Key Role of Achiral Additive

N. Abermil; G. Masson; J. Zhu 

Organic Letters

2009

Vol. 11 , num. 20, p. 4648-4651.

DOI : 10.1021/ol901920s

Chiral Bronsted Acid-Catalyzed Enantioselective Multicomponent Mannich Reaction: Synthesis of anti-1,3-Diamines Using Enecarbamates as Nucleophiles

G. Dagousset; F. Drouet; G. Masson; J. Zhu 

Organic Letters

2009

Vol. 11 , num. 23, p. 5546-5549.

DOI : 10.1021/ol9023985

Synthesis of L-3-hydroxy-4-methoxy-5-methylphenylalanol

N. Demoulin; J. Zhu 

Synlett

2009

num. 3, p. 466-468.

DOI : 10.1055/s-0028-1087548

IBX/TBAB-mediated oxidation of primary amines to nitriles

F. Drouet; P. Fontaine; G. Masson; J. Zhu 

Synthesis

2009

num. 8, p. 1370-1374.

DOI : 10.1055/s-0028-1087994

Ugi-post functionalization, from a single set of Ugi-adducts to two distinct heterocycles by microwave-assisted palladium-catalyzed cyclizations: tuning the reaction pathways by ligand switch

W. Erb; L. Neuville; J. Zhu 

Journal of Organic Chemistry

2009

Vol. 74 , num. 8, p. 3109-3115.

DOI : 10.1021/jo900210x

Synthesis of Pyrroles by Consecutive Multicomponent Reaction/[4 + 1] Cycloaddition of alpha -Iminonitriles with Isocyanides

P. Fontaine; G. Masson; J. Zhu 

Organic Letters

2009

Vol. 11 , num. 7, p. 1555-1558.

DOI : 10.1021/ol9001619

Palladium-catalyzed annulation of acyloximes with arynes (or alkynes): synthesis of phenanthridines and isoquinolines

T. Gerfaud; L. Neuville; J. Zhu 

Angewandte Chemie, International Edition

2009

Vol. 48 , num. 3, p. 572-577.

DOI : 10.1002/anie.200804683

Total synthesis of horsfiline: a palladium-catalyzed domino Heck-cyanation strategy

S. Jaegli; J-P. Vors; L. Neuville; J. Zhu 

Synlett

2009

num. 18, p. 2997-2999.

DOI : 10.1055/s-0029-1218004

Chiral Bronsted Acid-Catalyzed Enantioselective Three-Component Povarov Reaction

H. Liu; G. Dagousset; G. Masson; P. Retailleau; J. Zhu 

Journal of the American Chemical Society

2009

Vol. 131 , num. 13, p. 4598-4599.

DOI : 10.1021/ja900806q

Palladium-catalyzed domino N-arylation/carbopalladation/C-H functionalization: three-component synthesis of 3-(diarylmethylene)oxindoles

A. Pinto; L. Neuville; J. Zhu 

Tetrahedron Letters

2009

Vol. 50 , num. 26, p. 3602-3605.

DOI : 10.1016/j.tetlet.2009.03.086

Combination of lithium chloride and hexafluoroisopropanol for Friedel-Crafts reactions

M. Willot; J. C. Chen; J. Zhu 

Synlett

2009

num. 4, p. 577-580.

DOI : 10.1055/s-0028-1087566

Asymmetric Total Syntheses of (-)-Renieramycin M and G and (-)-Jorumycin Using Aziridine as a Lynchpin

Y-C. Wu; J. Zhu 

Organic Letters

2009

Vol. 11 , num. 23, p. 5558-5561.

DOI : 10.1021/ol9024919

Synthetic Studies on (-)-Lemonomycin: An Efficient Asymmetric Synthesis of Lemonomycinone Amide

Y-C. Wu; G. Bernadat; G. Masson; C. Couturier; T. Schlama et al. 

Journal of Organic Chemistry

2009

Vol. 74 , num. 5, p. 2046-2052.

DOI : 10.1021/jo8027449

Catalytic Asymmetric Passerini-Type Reaction: Chiral Aluminum-Organophosphate-Catalyzed Enantioselective alpha -Addition of Isocyanides to Aldehydes

T. Yue; M-X. Wang; D-X. Wang; G. Masson; J. Zhu 

Journal of Organic Chemistry

2009

Vol. 74 , num. 21, p. 8396-8399.

DOI : 10.1021/jo9017765

Bronsted Acid Catalyzed Enantioselective Three-Component Reaction Involving the alpha Addition of Isocyanides to Imines

T. Yue; M-X. Wang; D-X. Wang; G. Masson; J. Zhu 

Angewandte Chemie, International Edition

2009

Vol. 48 , num. 36, p. 6717-6721, S6717/1-S6717/100.

DOI : 10.1002/anie.200902385

2008

Highly Enantioselective Aza Morita-Baylis-Hillman Reaction Catalyzed by Bifunctional beta -Isocupreidine Derivatives

N. Abermil; G. Masson; J. Zhu 

Journal of the American Chemical Society

2008

Vol. 130 , num. 38, p. 12596-12597.

DOI : 10.1021/ja805122j

Copper-Mediated N-Cyclopropylation of Azoles, Amides, and Sulfonamides by Cyclopropylboronic Acid

S. Benard; L. Neuville; J. Zhu 

Journal of Organic Chemistry

2008

Vol. 73 , num. 16, p. 6441-6444.

DOI : 10.1021/jo801033y

Synthesis of dihydrophenanthridines by a sequence of Ugi-4CR and palladium-catalyzed intramolecular C-H functionalization

F. Bonnaterre; M. Bois-Choussy; J. Zhu 

Beilstein Journal of Organic Chemistry

2008

Vol. 4 , num. 10.

DOI : 10.3762/bjoc.4.10

Total synthesis of arylomycin A2, a signal peptidase I (SPase I) inhibitor

J. Dufour; L. Neuville; J. Zhu 

Synlett

2008

num. 15, p. 2355-2359.

DOI : 10.1055/s-2008-1078209

One-Pot Three-Component Synthesis of alpha -Iminonitriles by IBX/TBAB-Mediated Oxidative Strecker Reaction

P. Fontaine; A. Chiaroni; G. Masson; J. Zhu 

Organic Letters

2008

Vol. 10 , num. 8, p. 1509-1512.

DOI : 10.1021/ol800199b

Synthesis of alpha -keto amides by a molecular-sieves-promoted formal oxidative coupling of aliphatic aldehydes with isocyanides

J-M. Grassot; G. Masson; J. Zhu 

Angewandte Chemie, International Edition

2008

Vol. 47 , num. 5, p. 947-950.

DOI : 10.1002/anie.200704840

Synthesis of diastereomers of complestatin and chloropeptin I: substrate-dependent atropstereoselectivity of the intramolecular Suzuki-Miyaura reaction

Y. Jia; M. Bois-Choussy; J. Zhu 

Angewandte Chemie, International Edition

2008

Vol. 47 , num. 22, p. 4167-4172.

DOI : 10.1002/anie.200800599

Development of multicomponent and domino reactions based on alpha -isocyanoacetamide and 5-aminooxazole

G. Masson; L. Neuville; J. Zhu 

Seminars in Organic Synthesis, “A. Corbella” Summer School, 33rd, Gargnano, Italy, June 23-27, 2008

2008

p. 11-36

Palladium-Catalyzed Intramolecular C-Arylation of Benzylic Carbon: Synthesis of 3-Benzoxazolylisoindolinones by a Sequence of Ugi-4CR/Postfunctionalization

A. Salcedo; L. Neuville; J. Zhu 

Journal of Organic Chemistry

2008

Vol. 73 , num. 9, p. 3600-3603.

DOI : 10.1021/jo800266y

Palladium-Catalyzed Domino Intramolecular N-Arylation/Intermolecular C-C Bond Formation for the Synthesis of Functionalized Benzodiazepinediones

A. Salcedo; L. Neuville; C. Rondot; P. Retailleau; J. Zhu 

Organic Letters

2008

Vol. 10 , num. 5, p. 857-860.

DOI : 10.1021/ol7029799

Catalytic enantioselective Passerini three-component reaction

S-X. Wang; M-X. Wang; D-X. Wang; J. Zhu 

Angewandte Chemie, International Edition

2008

Vol. 47 , num. 2, p. 388-391.

DOI : 10.1002/anie.200704315

Hafnium Trifluoromethanesulfonate (Hafnium Triflate) as a Highly Efficient Catalyst for Chemoselective Thioacetalization and Transthioacetalization of Carbonyl Compounds

Y-C. Wu; J. Zhu 

Journal of Organic Chemistry

2008

Vol. 73 , num. 23, p. 9522-9524.

DOI : 10.1021/jo8021988

Asymmetric Total Synthesis of (-)-Quinocarcin

Y-C. Wu; M. Liron; J. Zhu 

Journal of the American Chemical Society

2008

Vol. 130 , num. 22, p. 7148-7152.

DOI : 10.1021/ja800662q

Asymmetric synthesis of 5-(1-hydroxyalkyl)tetrazoles by catalytic enantioselective Passerini-type reactions

T. Yue; M-X. Wang; D-X. Wang; J. Zhu 

Angewandte Chemie, International Edition

2008

Vol. 47 , num. 49, p. 9454-9457.

DOI : 10.1002/anie.200804213

2007

Modulating the reactivity of alpha -isocyanoacetates: multicomponent synthesis of 5-methoxyoxazoles and furopyrrolones

D. Bonne; M. Dekhane; J. Zhu 

Angewandte Chemie, International Edition

2007

Vol. 46 , num. 14, p. 2485-2488.

DOI : 10.1002/anie.200605005

Rapid synthesis of cyclodepsipeptides containing a sugar amino acid or a sugar amino alcohol by a sequence of a multicomponent reaction and acid-mediated macrocyclization

C. Bughin; G. Masson; J. Zhu 

Journal of Organic Chemistry

2007

Vol. 72 , num. 5, p. 1826-1829.

DOI : 10.1021/jo0621874

Total synthesis of the marine natural product (-)-cribrostatin 4 (renieramycin H)

X. Chen; J. Zhu 

Angewandte Chemie, International Edition

2007

Vol. 46 , num. 21, p. 3962-3965.

DOI : 10.1002/anie.200700539

Lithium bromide-promoted three-component synthesis of oxa-bridged tetracyclic tetrahydroisoquinoline derivatives

A. Fayol; E. Gonzalez-Zamora; M. Bois-Choussy; J. Zhu 

Heterocycles

2007

Vol. 73 , p. 729-742.

DOI : 10.3987/COM-07-S(U)54

Synthesis of DEFG ring of complestatin and chloropeptin I: highly atropdiastereoselective macrocyclization by intramolecular Suzuki-Miyaura reaction

Y. Jia; M. Bois-Choussy; J. Zhu 

Organic Letters

2007

Vol. 9 , num. 12, p. 2401-2404.

DOI : 10.1021/ol070889p

The enantioselective Morita-Baylis-Hillman reaction and its aza counterpart

G. Masson; C. Housseman; J. Zhu 

Angewandte Chemie, International Edition

2007

Vol. 46 , num. 25, p. 4614-4628.

DOI : 10.1002/anie.200604366

IBX-mediated oxidative Ugi-type multicomponent reactions: application to the N and C1 functionalization of tetrahydroisoquinoline

T. Ngouansavanh; J. Zhu 

Angewandte Chemie, International Edition

2007

Vol. 46 , num. 30, p. 5775-5778.

DOI : 10.1002/anie.200701603

Palladium-catalyzed three-component synthesis of 3-(diarylmethylene)oxindoles through a domino Sonogashira/carbopalladation/C-H activation/C-C bond-forming sequence

A. Pinto; L. Neuville; J. Zhu 

Angewandte Chemie, International Edition

2007

Vol. 46 , num. 18, p. 3291-3295.

DOI : 10.1002/anie.200605192

Palladium-catalyzed enantioselective domino Heck-cyanation sequence: development and application to the total synthesis of esermethole and physostigmine

A. Pinto; Y. Jia; L. Neuville; J. Zhu 

Chemistry–A European Journal

2007

Vol. 13 , num. 3, p. 961-967.

DOI : 10.1002/chem.200601016

Ammonium Chloride Promoted Three-Component Synthesis of 5-Iminooxazoline and Its Subsequent Transformation to Macrocyclodepsipeptide

T. Pirali; G. C. Tron; G. Masson; J. Zhu 

Organic Letters

2007

Vol. 9 , num. 25, p. 5275-5278.

DOI : 10.1021/ol7024372

Synthesis of Protected Chiral Vicinal Diaminoalcohols by Diastereoselective Intramolecular Benzylic Substitution from Bistrichloroacetimidates

C. Rondot; P. Retailleau; J. Zhu 

Organic Letters

2007

Vol. 9 , num. 2, p. 247-250.

DOI : 10.1021/ol0627202

Asymmetric Lewis acid catalyzed addition of isocyanides to aldehydes. Synthesis of 5-amino-2-(1-hydroxyalkyl)oxazoles

S. Wang; M-X. Wang; D-X. Wang; J. Zhu 

European Journal of Organic Chemistry

2007

num. 24, p. 4076-4080.

DOI : 10.1002/ejoc.200700340

Chiral Salen-Aluminum Complex as a Catalyst for Enantioselective alpha -Addition of Isocyanides to Aldehydes: Asymmetric Synthesis of 2-(1-Hydroxyalkyl)-5-aminooxazoles

S-X. Wang; M-X. Wang; D-X. Wang; J. Zhu 

Organic Letters

2007

Vol. 9 , num. 18, p. 3615-3618.

DOI : 10.1021/ol7014658

New Frontiers in Asymmetric Catalysis edited by Koichi Mikami and Mark Lautens

J. Zhu 

Angewandte Chemie, International Edition

2007

Vol. 46 , num. 47, p. 8938-8940.

DOI : 10.1002/anie.200785522

Preparation of ecteinascidin alkaloids, such as ecteinascidins 583 and 597

J. Zhu; M. Bois-Choussy; J. Chen; X. Chen 

Patent number(s) :

  • AT554093 (T)
  • EP1937689 (B1)
  • US8058435 (B2)
  • US2009171080 (A1)
  • JP2009512662 (A)
  • EP1937689 (A2)
  • WO2007045686 (A3)
  • EP1792904 (A1)
  • WO2007045686 (A2)
  • CA2626595 (A1)

2007

2006

Rapid access to oxindoles by the combined use of an Ugi four-component reaction and a microwave-assisted intramolecular Buchwald-Hartwig amidation reaction

F. Bonnaterre; M. Bois-Choussy; J. Zhu 

Organic Letters

2006

Vol. 8 , num. 19, p. 4351-4354.

DOI : 10.1021/ol061755z

5-aminooxazole as an internal traceless activator of C-terminal carboxylic acid: rapid access to diversely functionalized cyclodepsipeptides

C. Bughin; G. Zhao; H. Bienayme; J. Zhu 

Chemistry–A European Journal

2006

Vol. 12 , num. 4, p. 1174-1184.

DOI : 10.1002/chem.200500703

Asymmetric total syntheses of ecteinascidin 597 and ecteinascidin 583

J. Chen; X. Chen; M. Willot; J. Zhu 

Angewandte Chemie, International Edition

2006

Vol. 45 , num. 47, p. 8028-8032.

DOI : 10.1002/anie.200603179

Synthetic studies on ecteinascidin 743 (Et 743): asymmetric synthesis of a highly oxygenated tetrahydroisoquinoline via a key phenolic Mannich reaction

X. Chen; J. Chen; J. Zhu 

Synthesis

2006

num. 23, p. 4081-4086.

DOI : 10.1055/s-2006-950343

Total Synthesis of Ecteinascidin 743

J. Chen; X. Chen; M. Bois-Choussy; J. Zhu 

Journal of the American Chemical Society

2006

Vol. 128 , num. 1, p. 87-89.

DOI : 10.1021/ja0571794

Synthetic studies towards (-)-lemonomycin, synthesis of fused tetracycles

C. Couturier; T. Schlama; J. Zhu 

Synlett

2006

num. 11, p. 1691-1694.

DOI : 10.1055/s-2006-944225

Aziridinium from N,N-dibenzyl serine methyl ester: Synthesis of enantiomerically pure beta -amino and alpha ,beta -diamino esters

C. Couturier; J. Blanchet; T. Schlama; J. Zhu 

Organic Letters

2006

Vol. 8 , num. 10, p. 2183-2186.

DOI : 10.1021/ol060700u

Rapid synthesis of cyclopeptide alkaloid-like para-cyclophanes by combined use of Ugi-4CR and intramolecular SNAr reaction

P. Cristau; J-P. Vors; J. Zhu 

QSAR & Combinatorial Science

2006

Vol. 25 , num. 5-6, p. 519-526.

DOI : 10.1002/qsar.200540214

Mono alkylation of alpha -isocyano acetamide to its higher homologues

C. Housseman; J. Zhu 

Synlett

2006

num. 11, p. 1777-1779.

DOI : 10.1055/s-2006-944224

Importance of the structure of vancomycin binding pocket in designing compounds active against vancomycin-resistant enterococci (VRE)

Y. Jia; M. Bois-Choussy; A. Malabarba; C. Brunati; J. Zhu 

Journal of Antibiotics

2006

Vol. 59 , num. 9, p. 543-552.

DOI : 10.1038/ja.2006.75

Palladium-Catalyzed, Modular Synthesis of Highly Functionalized Indoles and Tryptophans by Direct Annulation of Substituted o-Haloanilines and Aldehydes

Y. Jia; J. Zhu 

Journal of Organic Chemistry

2006

Vol. 71 , num. 20, p. 7826-7834.

DOI : 10.1021/jo061471s

Design and synthesis of simple macrocycles active against vancomycin-resistant Enterococci (VRE)

Y. Jia; N. Ma; Z. Liu; M. Bois-Choussy; E. Gonzalez-Zamora et al. 

Chemistry–A European Journal

2006

Vol. 12 , num. 20, p. 5334-5351.

DOI : 10.1002/chem.200600137

Synthesis of 4-nitrophenyl sulfones and application in the modified Julia olefination

D. Mirk; J-M. Grassot; J. Zhu 

Synlett

2006

num. 8, p. 1255-1259.

DOI : 10.1055/s-2006-939682

Alcohols in isonitrile-based multicomponent reaction: Passerini reaction of alcohols in the presence of o-iodoxybenzoic acid

T. Ngouansavanh; J. Zhu 

Angewandte Chemie, International Edition

2006

Vol. 45 , num. 21, p. 3495-3497.

DOI : 10.1002/anie.200600588

Synthesis of 3-(Diarylmethylenyl)oxindole by a Palladium-Catalyzed Domino Carbopalladation/C-H Activation/C-C Bond-Forming Process

A. Pinto; L. Neuville; P. Retailleau; J. Zhu 

Organic Letters

2006

Vol. 8 , num. 21, p. 4927-4930.

DOI : 10.1021/ol062022h

One-pot synthesis of macrocycles by a tandem three-component reaction and intramolecular [3+2] cycloaddition

T. Pirali; G. C. Tron; J. Zhu 

Organic Letters

2006

Vol. 8 , num. 18, p. 4145-4148.

DOI : 10.1021/ol061782p

Preparation of beta-amino or alpha ,beta-diamino esters derived from serine

J. Zhu; C. Couturier; J. Blanchet 

Patent number(s) :

  • WO2006106244 (A3)
  • FR2884249 (A1)
  • WO2006106244 (A2)

2006

2005

Multicomponent Reaction, an overview

J. Zhu; X. Chen; J. Chen; Q. Wang 

Recent progress in Organic Synthesis; Beijing: Chemical Industry Press, 2005.

ISBN : 7-5025-7204-X

One or More CH Bond(s) Formed by Substitution: Reduction of C-N, -P, -Arsenic, -Antimony, -Bismuth, -Carbon, -Silicon, -Germanium, -Boron, and –Metal Bonds

J. Blanchet; Y. Jia; J. Zhu 

Comprehensive Organic Functional Group Transformations II; Cambridge: Elsevier, 2005. p. 31-78.

ISBN : 978-0-08-044256-3

Nouveau Composes Chiraux Dérives d’une Diamine ou d’un Aminoalcool, Monosulfonylés et carbonylés Porteurs d’un Groupe Pyrrolidinyle. Leur Préparation et Leurs Applications en Catalyse Asymétrique

G. Mignani; J. Turcono; J. Zhu 

Patent number(s) :

  • FR2865204 (B1)
  • WO2005080299 (A1)
  • FR2865204 (A1)

2005

One or more C-H bond(s) formed by substitution: reduction of carbon-nitrogen, -phosphorus, -arsenic, -antimony, -bismuth, -carbon, -boron and -metal bonds

J. Blanchet; Y. Jia; J. Zhu 

Comprehensive Organic Functional Group Transformations II; Amsterdam: Elsevier Pergamon, 2005. p. 31-78.

DOI : 10.1016/B0-08-044655-8/00002-7

Conformation-directed macrocyclization reactions

J. Blankenstein; J. Zhu 

European Journal of Organic Chemistry

2005

num. 10, p. 1949-1964.

DOI : 10.1002/ejoc.200400751

Exploiting the Dual Reactivity of o-Isocyanobenzamide: Three-Component Synthesis of 4-Imino-4H-3,1-benzoxazines

D. Bonne; M. Dekhane; J. Zhu 

Organic Letters

2005

Vol. 7 , num. 23, p. 5285-5288.

DOI : 10.1021/ol052239w

Mild Oxidative One-Carbon Homologation of Aldehyde to Amide

D. Bonne; M. Dekhane; J. Zhu 

Journal of the American Chemical Society

2005

Vol. 127 , num. 19, p. 6926-6927.

DOI : 10.1021/ja0511220

Synthetic Studies toward Ecteinascidin 743

X. Chen; J. Chen; M. De Paolis; J. Zhu 

Journal of Organic Chemistry

2005

Vol. 70 , num. 11, p. 4397-4408.

DOI : 10.1021/jo050408k

Asymmetric synthesis of protected γ-carboxy-L-glutamic acid

C. Couturier; M. Liron; T. Schlama; J. Zhu 

Synlett

2005

num. 5, p. 851-853.

DOI : 10.1055/s-2005-863734

Total synthesis of mauritines A, B, C, and F: Cyclopeptide alkaloids with a 14-membered paracyclophane unit

P. Cristau; T. Temal-Laib; M. Bois-Choussy; M-T. Martin; J-P. Vors et al. 

Chemistry–A European Journal

2005

Vol. 11 , num. 9, p. 2668-2679.

DOI : 10.1002/chem.200401070

Multicomponent synthesis of epoxy-tetrahydronaphthyridine and structural diversification by subsequent fragmentation

A. Fayol; J. Zhu 

Tetrahedron

2005

Vol. 61 , num. 48, p. 11511-11519.

DOI : 10.1016/j.tet.2005.09.017

Synthesis of alpha -isocyano-alpha -alkyl(aryl)acetamides and their use in the multicomponent synthesis of 5-aminooxazole, pyrrolo[3,4-b]pyridin-5-one and 4,5,6,7-tetrahydrofuro[2,3-c]pyridine

A. Fayol; C. Housseman; X. Sun; P. Janvier; H. Bienayme et al. 

Synthesis

2005

num. 1, p. 161-165.

DOI : 10.1055/s-2004-831225

Three-component synthesis of polysubstituted 6-azaindolines and its tricyclic derivatives

A. Fayol; J. Zhu 

Organic Letters

2005

Vol. 7 , num. 2, p. 239-242.

DOI : 10.1021/ol0477881

Synthesis of ring-A-substituted tryptophan by a palladium-catalyzed heteroannulation reaction

Y. Jia; J. Zhu 

Synlett

2005

num. 16, p. 2469-2472.

DOI : 10.1055/s-2005-917079

Identification of synthetic compounds active against VRE: the role of the lipidated aminoglucose and the structure of glycopeptide binding pocket

Y. Jia; E. Gonzalez-Zamora; N. Ma; Z. Liu; M. Bois-Choussy et al. 

Bioorganic & Medicinal Chemistry Letters

2005

Vol. 15 , num. 20, p. 4594-4599.

DOI : 10.1016/j.bmcl.2005.06.098

Microwave-Assisted Intramolecular Suzuki-Miyaura Reaction to Macrocycle, a Concise Asymmetric Total Synthesis of Biphenomycin B

R. Lepine; J. Zhu 

Organic Letters

2005

Vol. 7 , num. 14, p. 2981-2984.

DOI : 10.1021/ol050949w

Synthesis of beta -amino-alpha -hydroxy esters and beta -amino-alpha -azido ester by Sharpless asymmetric aminohydroxylation, byproducts analysis

Z. Liu; N. Ma; Y. Jia; M. Bois-Choussy; A. Malabarba et al. 

Journal of Organic Chemistry

2005

Vol. 70 , num. 7, p. 2847-2850.

DOI : 10.1021/jo047772o

Design and synthesis of macrocycles active against vancomycin-resistant enterococci (VRE): the interplay between D-Ala-D-Lac binding and hydrophobic effect

N. Ma; Y. Jia; Z. Liu; E. Gonzalez-Zamora; M. Bois-Choussy et al. 

Bioorganic & Medicinal Chemistry Letters

2005

Vol. 15 , num. 3, p. 743-746.

DOI : 10.1016/j.bmcl.2004.11.014

Synthesis of Chiral Vicinal Diamines by Highly Diastereoselective Three-Component Phenolic Mannich Reaction: Temperature-Dependent Stereodivergency

C. Rondot; J. Zhu 

Organic Letters

2005

Vol. 7 , num. 8, p. 1641-1644.

DOI : 10.1021/ol050334z

A three-component synthesis of (1,3-oxazol-2-yl)-1,2-dihydro(iso)quinoline and its further structural diversifications

G. C. Tron; J. Zhu 

Synlett

2005

num. 3, p. 532-534.

DOI : 10.1055/s-2005-862357

Multicomponent Reactions

 

Weinheim: Wiley, 2005.

ISBN : 3-527-30806-7

2004

Reeve’s synthesis of 2-imino-4-thiazolidinone from alkyl (aryl) trichloromethylcarbinol revisited, a three-component process from aldehyde, chloroform, and thiourea

J. Blanchet; J. Zhu 

Tetrahedron Letters

2004

Vol. 45 , num. 23, p. 4449-4452.

DOI : 10.1016/j.tetlet.2004.04.055

Ammonium Chloride Promoted Ugi Four-Component, Five-Center Reaction of alpha -Substituted alpha -Isocyano Acetic Acid: A Strong Solvent Effect

D. Bonne; M. Dekhane; J. Zhu 

Organic Letters

2004

Vol. 6 , num. 25, p. 4771-4774.

DOI : 10.1021/ol0479388

Strained-Cyclophane-Induced beta -Turn Template: Design, Synthesis, and Spectroscopic Characterization

P. Cristau; M-T. Martin; M-E. T. H. Dau; J-P. Vors; J. Zhu 

Organic Letters

2004

Vol. 6 , num. 18, p. 3183-3186.

DOI : 10.1021/ol0488439

Palladium- and Copper-Catalyzed Synthesis of Medium- and Large-Sized Ring-Fused Dihydroazaphenanthrenes and 1,4-Benzodiazepine-2,5-diones. Control of Reaction Pathway by Metal-Switching

G. Cuny; M. Bois-Choussy; J. Zhu 

Journal of the American Chemical Society

2004

Vol. 126 , num. 44, p. 14475-14484.

DOI : 10.1021/ja047472o

Truncated diastereoselective Passerini reaction, a rapid construction of polysubstituted oxazole and peptides having an alpha -hydroxy-beta -amino acid component

G. Cuny; R. Gamez-Montano; J. Zhu 

Tetrahedron

2004

Vol. 60 , num. 22, p. 4879-4885.

DOI : 10.1016/j.tet.2004.03.084

A short enantioselective synthesis of protected L-3-hydroxy-4-methoxy-5-methyl phenylalanine and its corresponding aldehyde – a common subunit of ecteinascidin-743, safracin and congeners

M. De Paolis; X. Chen; J. Zhu 

Synlett

2004

num. 4, p. 729-731.

DOI : 10.1055/s-2004-817763

Synthesis of Polysubstituted 4,5,6,7-Tetrahydrofuro[2,3-c]pyridines by a Novel Multicomponent Reaction

A. Fayol; J. Zhu 

Organic Letters

2004

Vol. 6 , num. 1, p. 115-118.

DOI : 10.1021/ol036167p

A short synthesis of (-)-deoxoprosophylline

A. Jourdant; J. Zhu 

Heterocycles

2004

Vol. 64 , p. 249-259.

DOI : 10.3987/COM-04-S(P)21

2003

Total synthesis of an atropdiastereomer of RP-66453 and determination of its absolute configuration

M. Bois-Choussy; P. Cristau; J. Zhu 

Angewandte Chemie, International Edition

2003

Vol. 42 , num. 35, p. 4238-4241.

DOI : 10.1002/anie.200351996

Rapid and diverse route to natural product-like biaryl ether containing macrocycles

P. Cristau; J-P. Vors; J. Zhu 

Tetrahedron

2003

Vol. 59 , num. 40, p. 7859-7870.

DOI : 10.1016/j.tet.2003.08.031

Solid-phase synthesis of natural product-like macrocycles by a sequence of Ugi-4CR and SNAr-based cycloetherification

P. Cristau; J-P. Vors; J. Zhu 

Tetrahedron Letters

2003

Vol. 44 , num. 30, p. 5575-5578.

DOI : 10.1016/S0040-4039(03)01378-9

One-pot synthesis of polyheterocycles by a palladium-catalyzed intramolecular N-arylation/C[bond]H activation/aryl[bond]aryl bond-forming domino process

G. Cuny; M. Bois-Choussy; J. Zhu 

Angewandte Chemie, International Edition

2003

Vol. 42 , num. 39, p. 4774-7.

DOI : 10.1002/anie.200351923

Synthetic studies on ecteinascidin 743: rapid access to the fully functionalized tetrahydroisoquinoline with a bridged 10-membered sulfur containing macrocycle

M. De Paolis; A. Chiaroni; J. Zhu 

Chemical Communications

2003

num. 23, p. 2896-2897.

DOI : 10.1039/b309824a

From central to planar chirality, the first example of atropenantioselective cycloetherification

G. Islas-Gonzalez; M. Bois-Choussy; J. Zhu 

Organic & Biomolecular Chemistry

2003

Vol. 1 , num. 1, p. 30-32.

DOI : 10.1039/b208905j

A one-pot four-component (ABC2) synthesis of macrocycles

P. Janvier; M. Bois-Choussy; H. Bienayme; J. Zhu 

Angewandte Chemie, International Edition

2003

Vol. 42 , num. 7, p. 811-814.

DOI : 10.1002/anie.200390216

Asymmetric synthesis of orthogonally protected (2S,4R)- and (2S,4S)-4-hydroxyornithine

R. Lepine; A-C. Carbonnelle; J. Zhu 

Synlett

2003

num. 10, p. 1455-1458.

DOI : 10.1055/s-2003-40840

Allo-aromadendrane- and picrotoxane-type sesquiterpenes from Dendrobium moniliforme

W. Zhao; Q. Ye; J. Dai; M-T. Martin; J. Zhu 

Planta Medica

2003

Vol. 69 , num. 12, p. 1136-1140.

DOI : 10.1055/s-2003-818005

Synthesis of isocyano peptides by dehydration of the N-formyl derivatives

G. Zhao; C. Bughin; H. Bienayme; J. Zhu 

Synlett

2003

num. 8, p. 1153-1154.

DOI : 10.1055/s-2003-39898

Recent developments in the isonitrile-based multicomponent synthesis of heterocycles

J. Zhu 

European Journal of Organic Chemistry

2003

num. 7, p. 1133-1144.

DOI : 10.1002/ejoc.200390167

2002

Studies toward the total synthesis of RP-66453

S. Boisnard; J. Zhu 

Tetrahedron Letters

2002

Vol. 43 , num. 14, p. 2577-2580.

DOI : 10.1016/S0040-4039(02)00307-6

N-Carbamate-Assisted Stereoselective Synthesis of Chiral Vicinal Amino Sulfides

M. De Paolis; J. Blankenstein; M. Bois-Choussy; J. Zhu 

Organic Letters

2002

Vol. 4 , num. 7, p. 1235-1238.

DOI : 10.1021/ol025743z

Synthesis of furoquinolines by a multicomponent domino process

A. Fayol; J. Zhu 

Angewandte Chemie, International Edition

2002

Vol. 41 , num. 19, p. 3633-3635.

DOI : 10.1002/1521-3773(20021004)41:19<3633::AID-ANIE3633>3.0.CO;2-T

Rapid access to tetracyclic ring system of lennoxamine type natural product by combined use of a novel three-component reaction and Pummerer cyclization

R. Gamez Montano; J. Zhu 

Chemical Communications

2002

num. 20, p. 2448-2449.

DOI : 10.1039/B207179G

Multicomponent domino process to oxa-bridged polyheterocycles and pyrrolopyridines, structural diversity derived from work-up procedure

R. Gamez-Montano; E. Gonzalez-Zamora; P. Potier; J. Zhu 

Tetrahedron

2002

Vol. 58 , num. 32, p. 6351-6358.

DOI : 10.1016/S0040-4020(02)00634-8

A five-component synthesis of hexasubstituted benzenes

P. Janvier; H. Bienayme; J. Zhu 

Angewandte Chemie, International Edition

2002

Vol. 41 , num. 22, p. 4291-4294.

DOI : 10.1002/1521-3773(20021115)41:22<4291::AID-ANIE4291>3.0.CO;2-D

Ammonium Chloride-Promoted Four-Component Synthesis of Pyrrolo[3,4-b]pyridin-5-ones

P. Janvier; X. Sun; H. Bienayme; J. Zhu 

Journal of the American Chemical Society

2002

Vol. 124 , num. 11, p. 2560-2567.

DOI : 10.1021/ja017563a

Wilkinson’s Catalyst Catalyzed Selective Hydrogenation of Olefin in the Presence of an Aromatic Nitro Function: A Remarkable Solvent Effect

A. Jourdant; E. Gonzalez-Zamora; J. Zhu 

Journal of Organic Chemistry

2002

Vol. 67 , num. 9, p. 3163-3164.

DOI : 10.1021/jo025595q

A Convergent Approach to Cyclopeptide Alkaloids: Total Synthesis of Sanjoinine G1

T. Temal-Laieb; J. Chastanet; J. Zhu 

Journal of the American Chemical Society

2002

Vol. 124 , num. 4, p. 583-590.

DOI : 10.1021/ja0170807

2001

An autoxidative approach to 1,2,3,4-tetrahydroisoquinolin-1-one and tetrahydro-β-carbolin-1-one

M. Bois-Choussy; M. De Paolis; J. Zhu 

Tetrahedron Letters

2001

Vol. 42 , num. 20, p. 3427-3430.

DOI : 10.1016/S0040-4039(01)00482-8

Asymmetric total synthesis of (-)-deoxoprosophylline

A. Jourdant; J. Zhu 

Tetrahedron Letters

2001

Vol. 42 , num. 20, p. 3431-3434.

DOI : 10.1016/S0040-4039(01)00483-X

Studies on the Total Synthesis of RP 66453: Synthesis of Fully Functionalized 15-Membered Biaryl-Containing Macrocycle

S. Boisnard; A-C. Carbonnelle; J. Zhu 

Organic Letters

2001

Vol. 3 , num. 13, p. 2061-2064.

DOI : 10.1021/ol016021v

A Rapid Access to Biaryl Ether Containing Macrocycles by Pairwise Use of Ugi 4CR and Intramolecular SNAr-Based Cycloetherification

P. Cristau; J-P. Vors; J. Zhu 

Organic Letters

2001

Vol. 3 , num. 25, p. 4079-4082.

DOI : 10.1021/ol0168420

Three component synthesis of oxa-bridged tetracyclic tetrahydroquinolines

E. Gonzalez-Zamora; A. Fayol; M. Bois-Choussy; A. Chiaroni; J. Zhu 

Chemical Communications

2001

num. 17, p. 1684-1685.

DOI : 10.1039/b104317j

4-Nitrophenyltriflate

Y. X. Jia; J. Zhu 

e-EROS Encyclopedia of Reagents for Organic Synthesis; 2001.

DOI : 10.1002/047084289X.rn00477

A Novel Multicomponent Synthesis of Polysubstituted 5-Aminooxazole and Its New Scaffold-Generating Reaction to Pyrrolo[3,4-b]pyridine

X. Sun; P. Janvier; G. Zhao; H. Bienayme; J. Zhu 

Organic Letters

2001

Vol. 3 , num. 6, p. 877-880.

DOI : 10.1021/ol007055q

Activation of a terminal carboxylic acid by an internal oxazole: a novel synthesis of macrocyclodepsipeptide

G. Zhao; X. Sun; H. Bienayme; J. Zhu 

Journal of the American Chemical Society

2001

Vol. 123 , num. 27, p. 6700-6701.

DOI : 10.1021/ja015854d

1,3,4,6,7,8-Hexahydro-1-methyl-2H-pyr- imido[1,2-a]pyrimidine (MTBD)

J. Zhu 

e-EROS Encyclopedia of Reagents for Organic Synthesis

2001

DOI : 10.1002/047084289X.rn00329.pub2

Polymer-Supported 1,5,7-Triazabicyclo[4.4.0]dec-5-ene (PTBD)

J. Zhu 

e-EROS Encyclopedia of Reagents for Organic Synthesis; 2001.

DOI : 10.1002/047084289X.rn00330

2000

An efficient stereoselective and stereodivergent synthesis of (2R,3R)- and (2R,3S)-3-hydroxypipecolic acids

A. Jourdant; J. Zhu 

Tetrahedron Letters

2000

Vol. 41 , num. 36, p. 7033-7036.

DOI : 10.1016/S0040-4039(00)01207-7

The first total synthesis of mauritine-A

T. Laïb; M. Bois-Chaussy; J. Zhu 

Tetrahedron Letters

2000

Vol. 41 , num. 40, p. 7645-7649.

DOI : 10.1016/S0040-4039(00)01335-6

An efficient total synthesis of K-13, a non-competitive inhibitor of ACE I

A. Bigot; M. Bois-Choussy; J. Zhu 

Tetrahedron Letters

2000

Vol. 41 , num. 23, p. 4573-4577.

DOI : 10.1016/S0040-4039(00)00695-X

Contribution to total synthesis of Vancomycin and Teicoplanin

M. Bois-Choussy; C. Vergne; L. Neuville; J. Zhu 

L’Actualité Chimique

2000

num. 7-8, p. 66-69.

Asymmetric Synthesis of Actinoidic Acid Derivatives

S. Boisnard; L. Neuville; M. Bois-Choussy; J. Zhu 

Organic Letters

2000

Vol. 2 , num. 16, p. 2459-2462.

DOI : 10.1021/ol006110s

A Novel Synthesis of Biaryl-Containing Macrocycles by a Domino Miyaura Arylboronate Formation: Intramolecular Suzuki Reaction

A-C. Carbonnelle; J. Zhu 

Organic Letters

2000

Vol. 2 , num. 22, p. 3477-3480.

DOI : 10.1021/ol006520g

Inhibitory salt effect on the SNAr based macrocycloetherification of a linear diarylheptanoid

G. Islas-Gonzalez; J. Zhu 

Synlett

2000

num. 3, p. 412-414.

DOI : 10.1055/s-2000-6519

Synthesis of model of phomopsin-ustiloxin-type antimitotic agents

T. Laib; J. Zhu 

Synlett

2000

num. 9, p. 1363-1365.

DOI : 10.1055/s-2000-7137

Synthesis of a model 22-membered AB-C-O-D ring of vancomycin containing biaryl and biaryl ether linkages

L. Neuville; M. Bois-Choussy; J. Zhu 

Tetrahedron Letters

2000

Vol. 41 , num. 11, p. 1747-1751.

DOI : 10.1016/S0040-4039(00)00046-0

Recent progress in isolation, bioactivity evaluation and total synthesis of diarylheptanoids

J. Zhu; G. Islas-Gonzalez; M. Bois-Choussy 

Organic Preparations and Procedures International

2000

Vol. 32 , num. 6, p. 505-546.

DOI : 10.1080/00304940009355948

1999

Total Synthesis of an Antitumor Agent RA-VII via an Efficient Preparation of Cycloisodityrosine

A. Bigot; M. E. T. H. Dau; J. Zhu 

Journal of Organic Chemistry

1999

Vol. 64 , num. 17, p. 6283-6296.

DOI : 10.1021/jo990432w

A high throughput synthesis of aryl triflate and aryl nonaflate promoted by a polymer supported base (PTBD)

S. Boisnard; J. Chastanet; J. Zhu 

Tetrahedron Letters

1999

Vol. 40 , num. 42, p. 7469-7472.

DOI : 10.1016/S0040-4039(99)01529-4

A Unified Strategy toward the Synthesis of Acerogenin-Type Macrocycles: Total Syntheses of Acerogenins A, B, C, and L and Aceroside IV

G. I. Gonzalez; J. Zhu 

Journal of Organic Chemistry

1999

Vol. 64 , num. 3, p. 914-924.

DOI : 10.1021/jo981844s

An asymmetric total synthesis of sanjoinine G1

T. Laib; J. Zhu 

Tetrahedron Letters

1999

Vol. 40 , num. 1, p. 83-86.

DOI : 10.1016/S0040-4039(98)80025-7

Design and synthesis of novel tridentate and tetradentate chiral ligands

L. Neuville; J. Chastanet; J. Zhu 

Tetrahedron Letters

1999

Vol. 40 , num. 39, p. 7087-7090.

DOI : 10.1016/S0040-4039(99)01454-9

4-Nitrophenyltriflate and 4-Nitrophenylnonaflate as New Perfluoroalkanesulfonyl Transfer Agents: Experimental and Computational Studies

L. Neuville; A. Bigot; M. E. T. H. Dau; J. Zhu 

Journal of Organic Chemistry

1999

Vol. 64 , num. 20, p. 7638-7642.

DOI : 10.1021/jo990559l

Total synthesis and conformational studies of hapalosin, N-desmethylhapalosin and 8-deoxyhapalosin

B. Wagner; G. I. Gonzalez; M. E. T. H. Dau; J. Zhu 

Bioorganic & Medicinal Chemistry

1999

Vol. 7 , num. 5, p. 737-747.

DOI : 10.1016/S0968-0896(98)00208-9

SNAr-based cycloetherification methodology: application in the synthesis of heterodectic macrocyclic peptides with endo aryl-aryl and aryl-alkyl ether bonds

J. Zhu 

Peptidomimetics Protocols; 1999. p. 293-320.

ISBN : 0-89603-517-4

DOI : 10.1385/0-89603-517-4:293

Recent developments in reversing glycopeptide-resistant pathogens

J. Zhu 

Expert Opinion on Therapeutic Patents

1999

Vol. 9 , num. 8, p. 1005-1019.

DOI : 10.1517/13543776.9.8.1005

1998

SNAr Based Cycloetherification Methodology: Application in the Synthesis of Heterodectic Macrocyclic Peptides with Endo Aryl-Aryl and Aryl-Alkyl ether Bonds

J. Zhu 

Peptidomimetics Protocols, Methods in Molecular Biology; New Jersey: The Humana Press Inc, 1998. p. 293-320.

Synthèse Totale de Produits Naturels Macrocycliques Biologiquement Actifs

J. Zhu 

Sciences Chimique

1998

Vol. 64 , p. 4-8.

Synthesis of cycloisodityrosine revisited: A selective ring forming process

A. Bigot; J. Zhu 

Tetrahedron Letters

1998

Vol. 39 , num. 7, p. 551-554.

DOI : 10.1016/S0040-4039(97)10664-5

Chemoenzymic Synthesis of D-N-Boc-3,5- dihydroxy-4-methoxyphenylglycine

M. Bois-Choussy; J. Zhu 

Journal of Organic Chemistry

1998

Vol. 63 , num. 16, p. 5662-5665.

DOI : 10.1021/jo980233x

Horse liver esterase catalyzed enantioselective hydrolysis of N,O-diacetyl-2-amino-1-arylethanol

T. Laib; J. Ouazzani; J. Zhu 

Tetrahedron: Asymmetry

1998

Vol. 9 , num. 1, p. 169-178.

DOI : 10.1016/S0957-4166(97)00610-1

Approach towards the total synthesis of cyclopeptide alkaloids

T. Laib; J. Zhu 

Tetrahedron Letters

1998

Vol. 39 , num. 3/4, p. 283-286.

DOI : 10.1016/S0040-4039(97)10513-5

Diastereoselective Synthesis of gamma -Hydroxy-beta -Amino Alcohols and (2S,3S)-beta -Hydroxyleucine from Chiral D-(N,N-Dibenzylamino)serine (TBDMS) Aldehyde

T. Laieb; J. Chastanet; J. Zhu 

Journal of Organic Chemistry

1998

Vol. 63 , num. 5, p. 1709-1713.

DOI : 10.1021/jo971468w

Asymmetric synthesis of 3,5-bis(isopropyloxy)-4-methoxyphenyl glycine by way of a diastereoselective Strecker reaction and an Evans electrophilic amination reaction

C. Vergne; J-P. Bouillon; J. Chastanet; M. Bois-Choussy; J. Zhu 

Tetrahedron: Asymmetry

1998

Vol. 9 , num. 17, p. 3095-3103.

DOI : 10.1016/S0957-4166(98)00312-7

An efficient chloro-deamination procedure, application to the synthesis of advanced vancomycin C-O-D-O-E ring

C. Vergne; M. Bois-Choussy; J. Zhu 

Synlett

1998

num. 10, p. 1159-1161.

DOI : 10.1055/s-1998-1857

A method for removal of N-Boc protecting groups from substrates on TFA-sensitive resins

A. J. Zhang; D. H. Russell; J. Zhu; K. Burgess 

Tetrahedron Letters

1998

Vol. 39 , num. 41, p. 7439-7442.

DOI : 10.1016/S0040-4039(98)01631-1

1997

Solution phase combinatorial synthesis of arylpiperazines

L. Neuville; J. Zhu 

Tetrahedron Letters

1997

Vol. 38 , num. 23, p. 4091-4094.

DOI : 10.1016/S0040-4039(97)00831-9

A formal total synthesis of deoxybouvardin

A. Bigot; R. Beugelmans; J. Zhu 

Tetrahedron

1997

Vol. 53 , num. 31, p. 10753-10764.

DOI : 10.1016/S0040-4020(97)00706-0

Synthesis of model tricyclic C-O-D-O-E-F-O-G ring of teicoplanin

M. Bois-Choussy; C. Vergne; L. Neuville; R. Beugelmans; J. Zhu 

Tetrahedron Letters

1997

Vol. 38 , num. 33, p. 5795-5798.

DOI : 10.1016/S0040-4039(97)01280-X

Novel vancomycin dimers with activity against vancomycin-resistant enterococci

K. Burgess; J. Zhu 

Chemtracts

1997

Vol. 10 , num. 11, p. 818-821.

Rapid and efficient solid phase syntheses of cyclic peptides with endocyclic biaryl ether bonds

K. Burgess; D. Lim; M. Bois-Choussy; J. Zhu 

Tetrahedron Letters

1997

Vol. 38 , num. 19, p. 3345-3348.

DOI : 10.1016/S0040-4039(97)00654-0

First Total Synthesis of Acerogenin C and Aceroside IV

G. I. Gonzalez; J. Zhu 

Journal of Organic Chemistry

1997

Vol. 62 , num. 22, p. 7544-7545.

DOI : 10.1021/jo9714324

A highly stereoselective synthesis of (2S, 3S)-beta -hydroxyleucine

T. Laib; J. Chastanet; J. Zhu 

Tetrahedron Letters

1997

Vol. 38 , num. 10, p. 1771-1772.

DOI : 10.1016/S0040-4039(97)00207-4

Synthesis of four atropdiastereoisomers of C-O-D-O-E ring of vancomycin by sequential cycloetherifications

C. Vergne; M. Bois-Choussy; R. Beugelmans; J. Zhu 

Tetrahedron Letters

1997

Vol. 38 , num. 8, p. 1403-1406.

DOI : 10.1016/S0040-4039(97)00036-1

Chemoenzymic synthesis of enantiomerically pure 4-fluoro-3-nitro and 3-fluoro-4-nitro phenylalanine

C. Vergne; M. Bois-Choussy; J. Ouazzani; R. Beugelmans; J. Zhu 

Tetrahedron: Asymmetry

1997

Vol. 8 , num. 3, p. 391-398.

DOI : 10.1016/S0957-4166(96)00524-1

A novel strategy towards the total synthesis of cyclopeptide alkaloids. Reply

J. Zhu 

Angewandte Chemie, International Edition

1997

Vol. 36 , num. 10, p. 1074-1075.

DOI : 10.1002/anie.199710742

4-Nitrophenyl triflate as a new triflating agent

J. Zhu; A. Bigot; M. Elise; T. H. Dau 

Tetrahedron Letters

1997

Vol. 38 , num. 7, p. 1181-1182.

DOI : 10.1016/S0040-4039(97)00024-5

SNAr-based macrocyclization via biaryl ether formation. Application in natural product synthesis

J. Zhu 

Synlett

1997

num. 2, p. 133-144.

DOI : 10.1055/s-1997-722

1996

Synthesis of a model bicyclic C-O-D-O-E ring of vancomycin by a one-pot, double SNAr based macrocyclization

R. Beugelmans; M. Bois-Choussy; C. Vergne; J-P. Bouillon; J. Zhu 

Chemical Communications

1996

num. 9, p. 1029-1030.

DOI : 10.1039/cc9960001029

A New Approach to the Synthesis of Piperazinomycin and Bouvardin: Facile Access to Cycloisodityrosine via an Intramolecular SNAr Reaction

R. Beugelmans; A. Bigot; M. Bois-Choussy; J. Zhu 

Journal of Organic Chemistry

1996

Vol. 61 , num. 2, p. 771-4.

DOI : 10.1021/jo951375j

Synthesis of Modified Carboxyl Binding Pockets of Vancomycin and Teicoplanin

M. Bois-Choussy; L. Neuville; R. Beugelmans; J. Zhu 

Journal of Organic Chemistry

1996

Vol. 61 , num. 26, p. 9309-9322.

DOI : 10.1021/jo961412m

Asymmetric Synthesis. 39.1 Synthesis of 2-(1-Aminoalkyl)piperidines via 2-Cyano-6-phenyl Oxazolopiperidine

O. Froelich; P. Desos; M. Bonin; J-C. Quirion; H-P. Husson et al. 

Journal of Organic Chemistry

1996

Vol. 61 , num. 19, p. 6700-6705.

DOI : 10.1021/jo960910s

Synthesis of hapalosin and 8-deoxy-hapalosin

B. Wagner; R. Beugelmans; J. Zhu 

Tetrahedron Letters

1996

Vol. 37 , num. 36, p. 6557-6560.

DOI : 10.1016/0040-4039(96)01415-3

A novel strategy towards the total synthesis of cyclopeptide alkaloids

J. Zhu; T. Laib; J. Chastanet; R. Beugelmans 

Angewandte Chemie, International Edition

1996

Vol. 35 , num. 21, p. 2517-2519.

DOI : 10.1002/anie.199625171

Selective hydroxy group protection of gallic acid

J. Zhu; J. Chastanet; R. Beugelmans 

Synthetic Communications

1996

Vol. 26 , num. 13, p. 2479-2486.

DOI : 10.1080/00397919608004560

1995

Procédé de préparation de composés d’intérêt par cyclisation intramoléculaire et formation d’un pont éther biaryl

R. Beugelmans; M. Bois-Choussy; J. Zhu; J. Chastanet 

Patent number(s) :

  • JPH09508920 (A)
  • EP0746568 (A1)
  • FR2716456 (B1)
  • FR2716456 (A1)
  • CA2183333 (A1)
  • WO9522558 (A1)

1995

Palladium catalyzed reductive deprotection of alloc: Transprotection and peptide bond formation

R. Beugelmans; L. Neuville; M. Bois-Choussy; J. Chastanet; J. Zhu 

Tetrahedron Letters

1995

Vol. 36 , num. 18, p. 3129-3132.

DOI : 10.1016/0040-4039(95)00449-M

The first synthesis of a model bicyclic D-O-E-F-O-G ring of teicoplanin via sequential intramolecular SNAr reactions

R. Beugelmans; L. Neuville; M. Bois-Choussy; J. Zhu 

Tetrahedron Letters

1995

Vol. 36 , num. 48, p. 8787-90.

DOI : 10.1016/0040-4039(95)01876-J

A new access to 14-membered macrocycle: synthesis of model F-O-G ring of teicoplanin

R. Beugelmans; S. Bourdet; J. Zhu 

Tetrahedron Letters

1995

Vol. 36 , num. 8, p. 1279-82.

DOI : 10.1016/0040-4039(95)00015-5

Synthesis of a modified carboxylate-binding pocket of vancomycin

M. Bois-Choussy; R. Beugelmans; J-P. Bouillon; J. Zhu 

Tetrahedron Letters

1995

Vol. 36 , num. 27, p. 4781-4.

DOI : 10.1016/0040-4039(95)00864-9

Asymmetric synthesis of (2S,3R) beta -(4-F-3-NO2) phenyl serine, D-(R)-4-methoxy-3,5-bistbutyldimethylsiloxy phenylglycine and their assemblage to C-O-D ring of vancomycin

J. Zhu; J-P. Bouillon; G. P. Singh 

Tetrahedron Letters

1995

Vol. 36 , num. 39, p. 7081-4.

DOI : 10.1016/0040-4039(95)01409-B

A Convergent Synthesis of 14-Membered F-O-G Ring Analogs of the Teicoplanin Binding Pocket via Intramolecular SNAr Reaction

J. Zhu; R. Beugelmans; S. Bourdet; J. Chastanet; G. Roussi 

Journal of Organic Chemistry

1995

Vol. 60 , num. 20, p. 6389-96.

DOI : 10.1021/jo00125a026

1994

A novel synthesis of K-13

R. Beugelmans; A. Bigot; J. Zhu 

Tetrahedron Letters

1994

Vol. 35 , num. 40, p. 7391-4.

DOI : 10.1016/0040-4039(94)85322-3

An easy access to functionalized diaryl ethers: formal total synthesis of K-13

R. Beugelmans; A. Bigot; J. Zhu 

Tetrahedron Letters

1994

Vol. 35 , num. 31, p. 5649-52.

DOI : 10.1016/S0040-4039(00)77270-4

SNAr-Based Macrocyclization: An Application to the Synthesis of Vancomycin Family Models

R. Beugelmans; G. P. Singh; M. Bois-Choussy; J. Chastanet; J. Zhu 

Journal of Organic Chemistry

1994

Vol. 59 , num. 19, p. 5535-42.

DOI : 10.1021/jo00098a010

The first examples of SNAr-based macrocyclization: synthesis of model carboxylate-binding pockets of vancomycin

R. Beugelmans; J. Zhu; N. Husson; M. Bois-Choussy; G. P. Singh 

Journal of the Chemical Society, Chemical Communications

1994

num. 4, p. 439-40.

DOI : 10.1039/c39940000439

Reductive deprotection of aryl allyl ethers with Pd(Ph3)4/NaBH4

R. Beugelmans; S. Bourdet; A. Bigot; J. Zhu 

Tetrahedron Letters

1994

Vol. 35 , num. 25, p. 4349-50.

DOI : 10.1016/S0040-4039(00)73351-X

1993

Elemental white phosphorus as a radical trap: a new and general route to phosphonic acids

D. H. R. Barton; J. Zhu 

Journal of the American Chemical Society

1993

Vol. 115 , num. 5, p. 2071-2.

DOI : 10.1021/ja00058a082

A SNAr based facile synthesis of triaryl diethers, degradation products of vancomycin and related glycopeptide antibiotics

R. Beugelmans; G. P. Singh; J. Zhu 

Tetrahedron Letters

1993

Vol. 34 , num. 48, p. 7741-4.

DOI : 10.1016/S0040-4039(00)61553-8

Synthesis of various substituted dibenzo[b,d]pyranones including amino acid derivatives by SRN1 methodology

R. Beugelmans; M. Bois-Choussy; J. Chastanet; M. Le Gleuher; J. Zhu 

Heterocycles

1993

Vol. 36 , num. 12, p. 2733-32.

DOI : 10.3987/COM-93-6494

A concise and efficient synthesis of protected actinoidic acid, the degradation product of vancomycin

J. Zhu; R. Beugelmans; A. Bigot; G. P. Singh; M. Bois-Choussy 

Tetrahedron Letters

1993

Vol. 34 , num. 46, p. 7401-4.

DOI : 10.1016/S0040-4039(00)60137-5

Asymmetric synthesis. 29. Preparation of 1,8-diazaspiro[5.5]undecane derivatives

J. Zhu; J. C. Quirion; H. P. Husson 

Journal of Organic Chemistry

1993

Vol. 58 , num. 23, p. 6451-6.

DOI : 10.1021/jo00075a048

1992

An efficient procedure for the regioselective monoprotection of 1,2-diols

D. H. R. Barton; J. Zhu 

Tetrahedron

1992

Vol. 48 , num. 39, p. 8337-46.

DOI : 10.1016/S0040-4020(01)86582-0

1991

Asymmetric synthesis. XXII. Formal synthesis of (-)-perhydrohistrionicotoxin

J. Zhu; J. Royer; J. C. Quirion; H. P. Husson 

Tetrahedron Letters

1991

Vol. 32 , num. 22, p. 2485-8.

DOI : 10.1016/S0040-4039(00)74361-9

1990

Study on the synthesis of some new biflavonoids. (VI). The catalytic hydrogenation of 3,3″-biflavones

Q. Wang; J. Zhu; Y. Li 

Chinese Science Bulletin

1990

Vol. 35 , num. 9, p. 744-6.

Synthesis of some new biflavonoids. IV. Synthesis of 3,3″-biflavone

J. Zhu; Q. Wang; Y. Li 

Huaxue Xuebao

1990

Vol. 48 , num. 2, p. 190-4.

1989

Synthesis of some new biflavonoids. (V). Total synthesis of O-hexamethyl brackenin

Y. Li; J. Zhu; F. Zhang; Q. Wang 

Gaodeng Xuexiao Huaxue Xuebao

1989

Vol. 10 , num. 6, p. 653-4.

Synthesis of some new biflavonoids. I. Synthesis of the aromatic 1,4-diketones

Q. Wang; J. Zhu; Y. Li; X. Pan; S. Li 

Lanzhou Daxue Xuebao, Ziran Kexueban

1989

Vol. 25 , num. 3, p. 60-3.

Asymmetric synthesis. XX. Preparation of a novel spiropiperidine system by the CN(R,S) method

J. Zhu; J. C. Quirion; H. P. Husson 

Tetrahedron Letters

1989

Vol. 30 , num. 46, p. 6323-6.

DOI : 10.1016/S0040-4039(01)93883-3

Asymmetric synthesis. XVIII. Preparation of chiral 1,2-diamines via the CN(R,S) method. Application to the synthesis of an analog of tetraponerine

J. Zhu; J. C. Quirion; H. P. Husson 

Tetrahedron Letters

1989

Vol. 30 , num. 38, p. 5137-40.

DOI : 10.1016/S0040-4039(01)93468-9

Synthesis of bisflavone-type compounds. (III). Selective demethoxylation of 1,4-bis(2′,4′,6′-trimethoxyphenyl)-1,4-butanedione

J. Zhu; Q. Wang; Y. Li 

Lanzhou Daxue Xuebao, Ziran Kexueban

1989

Vol. 25 , num. 1, p. 157-8.

Synthesis of some new biflavonoids. II. Synthesis of alpha ,alpha ‘-bichalcone

J. Zhu; Q. Wang; Y. Li; H. Yin 

Huaxue Xuebao

1989

Vol. 47 , num. 8, p. 821-3.

1988

Total synthesis of 3,3′-biflavone

J. Zhu; Q. Wang; Y. Li 

Journal of the Chemical Society, Chemical Communications

1988

num. 23, p. 1549-1550.

DOI : 10.1039/C39880001549