Publications

2019

Remote C(sp(3))-H Arylation and Vinylation of N-Alkoxypyridinium Salts to delta-Aryl and delta-Vinyl Alcohols

X. Bao; Q. Wang; J. Zhu 

Chemistry-A European Journal

2019-08-13

DOI : 10.1002/chem.201902918

Remote C(sp 3 )−H Arylation and Vinylation of N ‐Alkoxypyridinium Salts to δ‐Aryl and δ‐Vinyl Alcohols

X. Bao; Q. Wang; J. Zhu 

Chemistry – A European Journal

2019

Vol. 25 , num. 50, p. 11630-11634.

DOI : 10.1002/chem.201902918

Catalytic Enantioselective Pinacol and Meinwald Rearrangements for the Construction of Quaternary Stereocenters

H. Wu; Q. Wang; J. Zhu 

Journal of the American Chemical Society

2019

Vol. 141 , num. 29, p. 11372-11377.

DOI : 10.1021/jacs.9b04551

Copper-Catalyzed 1,2-Methoxy Methoxycarbonylation of Alkenes with Methyl Formate

B. Budai; A. Leclair; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2019

Vol. 58 , num. 30, p. 10305-10309.

DOI : 10.1002/anie.201904263

Catalytic Kinetic Resolution by Enantioselective Aromatization: Conversion of Racemic Intermediates of the Barton-Zard Reaction into Enantioenriched 3-Arylpyrroles

S-C. Zheng; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2019

Vol. 58 , num. 27, p. 9215-9219.

DOI : 10.1002/anie.201903589

Iron‐Catalysed Remote C(sp 3 )−H Azidation of O ‐Acyl Oximes and N ‐Acyloxy Imidates Enabled by 1,5‐Hydrogen Atom Transfer of Iminyl and Imidate Radicals: Synthesis of γ‐Azido Ketones and β‐Azido Alcohols

R. O. Torres‐Ochoa; A. Leclair; Q. Wang; J. Zhu 

Chemistry – A European Journal

2019

Vol. 25 , num. 40, p. 9477-9484.

DOI : 10.1002/chem.201901079

Formal [4+1] Cycloaddition of o ‐Aminobenzyl Chlorides with Isocyanides: Synthesis of 2‐Amino‐3‐Substituted Indoles

J. A. W. Jong; X. Bao; Q. Wang; J. Zhu 

Helvetica Chimica Acta

2019

Vol. 102 , num. 3, p. e1900002.

DOI : 10.1002/hlca.201900002

Recent Advances in Catalytic Enantioselective Rearrangement

H. Wu; Q. Wang; J. Zhu 

European Journal of Organic Chemistry

2019

Vol. 2019 , num. 10, p. 1964-1980.

DOI : 10.1002/ejoc.201801799

Intramolecular Arylation of Tertiary Enamides through Pd(OAc)2-Catalyzed Dehydrogenative Cross-Coupling Reaction: Construction of Fused N-Heterocyclic Scaffolds and Synthesis of Isoindolobenzazepine Alkaloids

W. Zhu; S. Tong; J. Zhu; M-X. Wang 

The Journal of Organic Chemistry

2019

Vol. 84 , num. 5, p. 2870-2878.

DOI : 10.1021/acs.joc.9b00010

Copper-catalyzed remote C(sp3)–H azidation and oxidative trifluoromethylation of benzohydrazides

X. Bao; Q. Wang; J. Zhu 

Nature Communications

2019

Vol. 10 , num. 1, p. 769.

DOI : 10.1038/s41467-019-08741-w

Stereoselective Total Synthesis of Eburnane-Type Alkaloids Enabled by Conformation-Directed Cyclization and Rearrangement

G. Li; C. Piemontesi; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2019

Vol. 58 , num. 9, p. 2870-2874.

DOI : 10.1002/anie.201813920

Dual Photoredox/Copper Catalysis for the Remote C(sp3 )−H Functionalization of Alcohols and Alkyl Halides by N -Alkoxypyridinium Salts

X. Bao; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2019

Vol. 58 , num. 7, p. 2139-2143.

DOI : 10.1002/anie.201813356

Construction of Quaternary Stereocenters by Palladium-Catalyzed Carbopalladation-Initiated Cascade Reactions

Y. Ping; Y. Li; J. Zhu; W. Kong 

Angewandte Chemie International Edition

2019

Vol. 58 , num. 6, p. 1562-1573.

DOI : 10.1002/anie.201806088

Catalytic Atropenantioselective Heteroannulation between Isocyanoacetates and Alkynyl Ketones: Synthesis of Enantioenriched Axially Chiral 3-Arylpyrroles

S-C. Zheng; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2019

Vol. 58 , num. 5, p. 1494-1498.

DOI : 10.1002/anie.201812654

Catalytic Enantioselective α-Ketol Rearrangement

H. Wu; R. Andres; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2019

Vol. 58 , num. 2, p. 499-503.

DOI : 10.1002/anie.201812244

2018

From isonitrile to nitrile via ketenimine intermediate: Palladium-catalyzed 1,1-carbocyanation of ally carbonate by alpha-isocyanoacetate

G. Qiu; C. Sornay; D. Savary; S-C. Zheng; Q. Wang et al. 

Tetrahedron

2018-12-06

Vol. 74 , num. 49, p. 6966-6971.

DOI : 10.1016/j.tet.2018.10.032

Lewis acid catalyst-steered divergent synthesis of functionalized vicinal amino alcohols and pyrroles from tertiary enamides

X-M. Xu; C-H. Lei; S. Tong; J. Zhu; M-X. Wang 

Organic Chemistry Frontiers

2018-11-07

Vol. 5 , num. 21, p. 3138-3142.

DOI : 10.1039/c8qo00839f

Enantioselective total synthesis of (+)-Peganumine A

C. Piemontesi; Q. Wang; J. Zhu 

Abstracts Of Papers Of The American Chemical Society

2018-08-19

256th National Meeting and Exposition of the American-Chemical-Society (ACS) – Nanoscience, Nanotechnology and Beyond, Boston, MA, Aug 19-23, 2018.

Metamorphosis of cycloalkenes for the divergent total synthesis of polycyclic indole alkaloids

Z. Xu; Q. Wang; J. Zhu 

Chemical Society Reviews

2018

Vol. 47 , num. 21, p. 7882-7898.

DOI : 10.1039/C8CS00454D

Copper-catalyzed methylative difunctionalization of alkenes

X. Bao; T. Yokoe; T. M. Ha; Q. Wang; J. Zhu 

Nature Communications

2018

Vol. 9 , num. 1, p. 1995-1999.

DOI : 10.1038/s41467-018-06246-6

Chiral phosphoric acid-catalyzed enantioselective three-component Mannich reaction of acyclic ketones, aldehydes and anilines

S. Tong; Q. Wang; M-X. Wang; J. Zhu 

Tetrahedron

2018

Vol. 74 , num. 38, p. 5143-5149.

DOI : 10.1016/j.tet.2018.05.055

Copper-Catalyzed Arylation of Remote C(sp3 )−H Bonds in Carboxamides and Sulfonamides

Z. Li; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2018

Vol. 57 , num. 40, p. 13288-13292.

DOI : 10.1002/anie.201807623

Still Unconquered: Enantioselective Passerini and Ugi Multicomponent Reactions

Q. Wang; D-X. Wang; M-X. Wang; J. Zhu 

Accounts of Chemical Research

2018

Vol. 51 , num. 5, p. 1290-1300.

DOI : 10.1021/acs.accounts.8b00105

Heteroannulation of Arynes with α-Amino Imides: Synthesis of 2,2-Disubstituted Indolin-3-ones and Application to the Enantioselective Total Synthesis of (+)-Hinckdentine A

R. O. Torres-Ochoa; T. Buyck; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2018

Vol. 57 , num. 20, p. 5679-5683.

DOI : 10.1002/anie.201800746

Copper-Catalyzed Enantioselective Arylative Desymmetrization of Prochiral Cyclopentenes with Diaryliodonium Salts

H. Wu; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2018

Vol. 57 , num. 10, p. 2721-2725.

DOI : 10.1002/anie.201713329

Palladium-Catalyzed Enantioselective Desymmetrizing Aza-Wacker Reaction: Development and Application to the Total Synthesis of (−)-Mesembrane and (+)-Crinane

X. Bao; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2018

Vol. 57 , num. 7, p. 1995-1909.

DOI : 10.1002/anie.201712521

Cooperative Pd/Cu Catalysis: Multicomponent Synthesis of Tetrasubstituted Imidazolones from Methyl α-Isocyanoacetates, Primary Amines, and Aryl(vinyl) Iodides

A. Clemenceau; Q. Wang; J. Zhu 

Organic Letters

2018

Vol. 20 , num. 1, p. 126-129.

DOI : 10.1021/acs.orglett.7b03479

2017

Catalytic Enantioselective Double Carbopalladation/C−H Functionalization with Statistical Amplification of Product Enantiopurity: A Convertible Linker Approach

S. Tong; A. Limouni; Q. Wang; M-X. Wang; J. Zhu 

Angewandte Chemie International Edition

2017

Vol. 56 , num. 45, p. 14192-14196.

DOI : 10.1002/anie.201709133

Copper-Catalyzed Enantioselective Domino Arylation/Semipinacol Rearrangement of Allylic Alcohols with Diaryliodonium Salts

H. Wu; Q. Wang; J. Zhu 

Chemistry – A European Journal

2017

Vol. 23 , num. 53, p. 13037-13041.

DOI : 10.1002/chem.201703563

Silver Nitrate-Catalyzed Isocyanide Insertion/Lactamization Sequence to Imidazolones and Quinazolin-4-ones: Development and Application in Natural Product Synthesis

A. Clemenceau; Q. Wang; J. Zhu 

Organic Letters

2017

Vol. 19 , num. 18, p. 4872-4875.

DOI : 10.1021/acs.orglett.7b02334

α-Oxo-Ketenimines from Isocyanides and α-Haloketones: Synthesis and Divergent Reactivity

M. Mamboury; Q. Wang; J. Zhu 

Chemistry – A European Journal

2017

Vol. 23 , num. 52, p. 12744-12748.

DOI : 10.1002/chem.201703458

Copper-Catalyzed Three-Component Carboazidation of Alkenes with Acetonitrile and Sodium Azide

A. Bunescu; T. M. Ha; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2017

Vol. 56 , num. 35, p. 10555-10558.

DOI : 10.1002/anie.201705353

Palladium-Catalyzed Enantioselective Narasaka-Heck Reaction/Direct C−H Alkylation of Arenes: Iminoarylation of Alkenes

X. Bao; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2017

Vol. 56 , num. 32, p. 9577-9581.

DOI : 10.1002/anie.201705641

Silver-Catalyzed Three-Component 1,1-Aminoacylation of Homopropargylamines: α-Additions for Both Terminal Alkynes and Isocyanides

S. Tong; C. Piemontesi; Q. Wang; M-X. Wang; J. Zhu 

Angewandte Chemie International Edition

2017

Vol. 56 , num. 27, p. 7958-7962.

DOI : 10.1002/anie.201704727

Fluorophores for Excited-State Intramolecular Proton Transfer by an Yttrium Triflate Catalyzed Reaction of Isocyanides with Thiocarboxylic Acids

S. Tong; S. Zhao; Q. He; Q. Wang; M-X. Wang et al. 

Angewandte Chemie International Edition

2017

Vol. 56 , num. 23, p. 6599-6603.

DOI : 10.1002/anie.201702488

Organocatalytic Enantioselective Acyloin Rearrangement of α-Hydroxy Acetals to α-Alkoxy Ketones

H. Wu; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2017

Vol. 56 , num. 21, p. 5858-5861.

DOI : 10.1002/anie.201701098

Organocatalytic Nucleophilic Addition of Hydrazones to Imines: Synthesis of Enantioenriched Vicinal Diamines

Y. Wang; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2017

Vol. 56 , num. 20, p. 5612-5615.

DOI : 10.1002/anie.201702295

Water as a Hydride Source in Palladium-Catalyzed Enantioselective Reductive Heck Reactions

W. Kong; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2017

Vol. 56 , num. 14, p. 3987-3991.

DOI : 10.1002/anie.201700195

To each his own: isonitriles for all flavors. Functionalized isocyanides as valuable tools in organic synthesis

M. Giustiniano; A. Basso; V. Mercalli; A. Massarotti; E. Novellino et al. 

Chemical Society Reviews

2017

Vol. 46 , num. 5, p. 1295-1357.

DOI : 10.1039/C6CS00444J

Palladium-Catalyzed Three-Component Reaction of Propargyl Carbonates, Isocyanides, and Alcohols or Water: Switchable Synthesis of Pyrroles and Its Bicyclic Analogues

G. Qiu; Q. Wang; J. Zhu 

Organic Letters

2017

Vol. 19 , num. 1, p. 270-273.

DOI : 10.1021/acs.orglett.6b03592

2016

Enantioselective Synthesis of Quaternary α-Amino Acids Enabled by the Versatility of the Phenylselenonyl Group

A. Clemenceau; Q. Wang; J. Zhu 

Chemistry – A European Journal

2016

Vol. 22 , num. 51, p. 18368-18372.

DOI : 10.1002/chem.201604781

Organocatalytic Enantioselective Vinylogous Pinacol Rearrangement Enabled by Chiral Ion Pairing

H. Wu; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2016

Vol. 55 , num. 49, p. 15411-15414.

DOI : 10.1002/anie.201609911

Ketenimines from Isocyanides and Allyl Carbonates: Palladium-Catalyzed Synthesis of β,γ-Unsaturated Amides and Tetrazoles

G. Qiu; M. Mamboury; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2016

Vol. 55 , num. 49, p. 15377-15381.

DOI : 10.1002/anie.201609034

Enantioselective Synthesis of (+)-Peganumine A

C. Piemontesi; Q. Wang; J. Zhu 

Journal of the American Chemical Society

2016

Vol. 138 , num. 35, p. 11148-11151.

DOI : 10.1021/jacs.6b07846

Copper-catalysed cyanoalkylative cycloetherification of alkenes to 1,3-dihydroisobenzofurans: development and application to the synthesis of citalopram

T. M. Ha; Q. Wang; J. Zhu 

Chemical Communications

2016

Vol. 52 , num. 74, p. 11100-11103.

DOI : 10.1039/C6CC06356J

Synthesis of Diversely Functionalized Oxindoles Enabled by Migratory Insertion of Isocyanide to a Transient σ-Alkylpalladium(II) Complex

W. Kong; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2016

Vol. 55 , num. 33, p. 9714-9718.

DOI : 10.1002/anie.201603950

Copper-Catalyzed Formal [2+2+1] Heteroannulation of Alkenes, Alkylnitriles, and Water: Method Development and Application to a Total Synthesis of (±)-Sacidumlignan D

T. M. Ha; C. Chatalova-Sazepin; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2016

Vol. 55 , num. 32, p. 9249-9252.

DOI : 10.1002/anie.201604528

Switchable [3+2] and [4+2] Heteroannulation of Primary Propargylamines with Isonitriles to Imidazoles and 1,6-Dihydropyrimidines: Catalyst Loading Enabled Reaction Divergence

S. Tong; Q. Wang; M-X. Wang; J. Zhu 

Chemistry – A European Journal

2016

Vol. 22 , num. 24, p. 8332-8338.

DOI : 10.1002/chem.201601560

Chiral Phosphoric Acid-Catalyzed Enantioselective Formal [3+2] Cycloaddition of Azomethine Imines with Enecarbamates

Y. Wang; Q. Wang; J. Zhu 

Chemistry – A European Journal

2016

Vol. 22 , num. 24, p. 8084-8088.

DOI : 10.1002/chem.201601548

Enantioselective Total Synthesis of (−)-Terengganensine A

C. Piemontesi; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2016

Vol. 55 , num. 22, p. 6556-6560.

DOI : 10.1002/anie.201602374

Chiral Phosphoric Acid Catalyzed Asymmetric Ugi Reaction by Dynamic Kinetic Resolution of the Primary Multicomponent Adduct

Y. Zhang; Y-F. Ao; Z-T. Huang; D-X. Wang; M-X. Wang et al. 

Angewandte Chemie International Edition

2016

Vol. 55 , num. 17, p. 5282-5285.

DOI : 10.1002/anie.201600751

Synthesis of Vinyl Isocyanides and Development of a Convertible Isonitrile

M. Spallarossa; Q. Wang; R. Riva; J. Zhu 

Organic Letters

2016

Vol. 18 , num. 7, p. 1622-1625.

DOI : 10.1021/acs.orglett.6b00483

Catalytic Asymmetric Tandem Reaction of Tertiary Enamides: Expeditious Synthesis of Pyrrolo[2,1-a]isoquinoline Alkaloid Derivatives

X-M. Xu; L. Zhao; J. Zhu; M-X. Wang 

Angewandte Chemie International Edition

2016

Vol. 55 , num. 11, p. 3799-3803.

DOI : 10.1002/anie.201600119

Total Synthesis of (±)-Strictamine

W. Ren; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2016

Vol. 55 , num. 10, p. 3500-3503.

DOI : 10.1002/anie.201511638

Synthesis of Oxazolidin-2-ones by Oxidative Coupling of Isonitriles, Phenyl Vinyl Selenone, and Water

T. Buyck; D. Pasche; Q. Wang; J. Zhu 

Chemistry – A European Journal

2016

Vol. 22 , num. 7, p. 2278-2281.

DOI : 10.1002/chem.201505050

Enantioselective Total Syntheses of (−)-Rhazinilam, (−)-Leucomidine B, and (+)-Leuconodine F

D. Dagoneau; Z. Xu; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2016

Vol. 55 , num. 2, p. 760-763.

DOI : 10.1002/anie.201508906

2015

Palladium-Catalyzed Enantioselective Domino Heck/Intermolecular C–H Bond Functionalization: Development and Application to the Synthesis of (+)-Esermethole

W. Kong; Q. Wang; J. Zhu 

Journal of the American Chemical Society

2015

Vol. 137 , num. 51, p. 16028-16031.

DOI : 10.1021/jacs.5b11625

An Enantioselective Total Synthesis of (−)-Isoschizogamine

Z. Xu; X. Bao; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2015

Vol. 54 , p. 14937-14940.

DOI : 10.1002/anie.201508150

Sulfonamide and Tertiary Amine as Nucleophiles in Pd(II)-Catalyzed Diamination of Alkynes: Synthesis of Tetracyclic Indolobenzothiazine S,S‑Dioxides

T. M. Ha; B. Yao; Q. Wang; J. Zhu 

Organic Letters

2015

Vol. 17 , num. 21, p. 5256-5259.

DOI : 10.1021/acs.orglett.5b02621

Aqueous Titanium Trichloride Promoted Reductive Cyclization of o-Nitrostyrenes to Indoles: Development and Application to the Synthesis of Rizatriptan and Aspidospermidine

S. Tong; Z. Xu; M. Mamboury; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2015

Vol. 54 , num. 40, p. 11809-11812.

DOI : 10.1002/anie.201505713

Synthesis of diverse di- to penta-substituted 1,2-dihydropyridine derivatives from gold(I)-catalyzed intramolecular addition of tertiary enamides to alkynes

X. Zhang; X-M. Xu; L. Zhao; J. You; J. Zhu et al. 

Tetrahedron Letters

2015

Vol. 56 , num. 25, p. 3898-3901.

DOI : 10.1016/j.tetlet.2015.04.105

Total Syntheses of (−)-Mersicarpine, (−)-Scholarisine G, (+)-Melodinine E, (−)-Leuconoxine, (−)-Leuconolam, (−)-Leuconodine A, (+)-Leuconodine F, and (−)-Leuconodine C: Self-Induced Diastereomeric Anisochronism (SIDA) Phenomenon for Scholarisine G and Leuconodines A and C

Z. Xu; Q. Wang; J. Zhu 

Journal of the American Chemical Society

2015

Vol. 137 , num. 20, p. 6712-6724.

DOI : 10.1021/jacs.5b03619

Synthesis of Functionalized Epoxides by Copper-Catalyzed Alkylative Epoxidation of Allylic Alcohols with Alkyl Nitriles

A. Bunescu; Q. Wang; J. Zhu 

Organic Letters

2015

Vol. 17 , num. 8, p. 1890-1893.

DOI : 10.1021/acs.orglett.5b00571

Pd/C-Catalyzed Cyclizative Cross-Coupling of Two ortho-Alkynylanilines under Aerobic Conditions: Synthesis of 2,3’-Bisindoles

B. Yao; Q. Wang; J. Zhu 

Chemistry – A European Journal

2015

Vol. 21 , num. 20, p. 7413-7416.

DOI : 10.1002/chem.201501020

Integrated One-Pot Synthesis of 1,3-Oxazinan-2-ones from Isocyanoacetates and Phenyl Vinyl Selenones

T. Buyck; Q. Wang; J. Zhu 

CHIMIA International Journal for Chemistry

2015

Vol. 69 , num. 4, p. 199-202.

DOI : 10.2533/chimia.2015.199

Copper-Catalyzed Intermolecular Carboetherification of Unactivated Alkenes by Alkyl Nitriles and Alcohols

C. Chatalova-Sazepin; Q. Wang; G. M. Sammis; J. Zhu 

Angewandte Chemie International Edition

2015

Vol. 54 , num. 18, p. 5443-5446.

DOI : 10.1002/anie.201412357

2-(Methoxycarbonyl)ethyl as a Removable N-Protecting Group: Synthesis of Indoloisoquinolinones by Pd(II)-Catalyzed Intramolecular Diamination of Alkynes

T. M. Ha; B. Yao; Q. Wang; J. Zhu 

Organic Letters

2015

Vol. 17 , num. 7, p. 1750-1753.

DOI : 10.1021/acs.orglett.5b00526

Copper-Catalyzed Cyanomethylation of Allylic Alcohols with Concomitant 1,2-Aryl Migration: Efficient Synthesis of Functionalized Ketones Containing an α-Quaternary Center

A. Bunescu; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2015

Vol. 54 , num. 10, p. 3132-3135.

DOI : 10.1002/anie.201411657

Enantioselective Synthesis of Putative Lipiarmycin Aglycon Related to Fidaxomicin/Tiacumicin B

W. Erb; J-M. Grassot; D. Linder; L. Neuville; J. Zhu 

Angewandte Chemie International Edition

2015

Vol. 54 , num. 6, p. 1929-1932.

DOI : 10.1002/anie.201409475

Tuning the Reactivity of Isocyano Group: Synthesis of Imidazoles and Imidazoliums from Propargylamines and Isonitriles in the Presence of Multiple Catalysts

S. Tong; Q. Wang; M-X. Wang; J. Zhu 

Angewandte Chemie International Edition

2015

Vol. 54 , num. 4, p. 1293-1297.

DOI : 10.1002/anie.201410113

Chiral Calcium–BINOL Phosphate Catalyzed Diastereo- and Enantioselective Synthesis of syn-1,2-Disubstituted 1,2-Diamines: Scope and Mechanistic Studies

C. Lalli; A. Dumoulin; C. Lebée; F. Drouet; V. Guérineau et al. 

Chemistry – A European Journal

2015

Vol. 21 , num. 4, p. 1704-1712.

DOI : 10.1002/chem.201405286

Pd-Catalyzed Dehydrogenative Aryl−Aryl Bond Formation via Double C(sp2)−H Bond Activation: Efficient Synthesis of [3,4]-Fused Oxindoles

A. Bunescu; T. Piou; Q. Wang; J. Zhu 

Organic Letters

2015

Vol. 17 , num. 2, p. 334-337.

DOI : 10.1021/ol503442n

2014

Plastidic type I signal peptidase 1 is a redox-dependent thylakoidal processing peptidase

T. Midorikawa; J. K. Endow; J. Dufour; J. Zhu; K. Inoue 

The Plant Journal

2014

Vol. 80 , num. 4, p. 592-603.

DOI : 10.1111/tpj.12655

Copper-Mediated/Catalyzed Oxyalkylation of Alkenes with Alkylnitriles

A. Bunescu; Q. Wang; J. Zhu 

Chemistry – A European Journal

2014

Vol. 20 , num. 45, p. 14633-14636.

DOI : 10.1002/chem.201405102

Unified Strategy to Monoterpene Indole Alkaloids: Total Syntheses of (±)-Goniomitine, (±)-1,2-Dehydroaspidospermidine, (±)-Aspidospermidine, (±)-Vincadifformine, and (±)-Kopsihainanine A

O. Wagnières; Z. Xu; Q. Wang; J. Zhu 

Journal of the American Chemical Society

2014

Vol. 136 , num. 42, p. 15102-15108.

DOI : 10.1021/ja509329x

Functionalized imidazoliniums from the three-component domino reaction of N-formylmethylcarboxamides with amines and isocyanides

C-H. Lei; L. Zhao; D-X. Wang; J. Zhu; M-X. Wang 

Organic Chemistry Frontiers

2014

Vol. 1 , num. 8, p. 909-913.

DOI : 10.1039/C4QO00203B

Mechanistic Study on the Palladium(II)-Catalyzed Synthesis of 2,3-Disubstituted Indoles Under Aerobic Conditions: Anion Effects and the Development of a Low-Catalyst-Loading Process

B. Yao; Q. Wang; J. Zhu 

Chemistry – A European Journal

2014

Vol. 20 , p. 12255-12261.

DOI : 10.1002/chem.201403612

Phosphoric Acid Catalyzed Desymmetrization of Bicyclic Bislactones Bearing an All-Carbon Stereogenic Center: Total Syntheses of (−)-Rhazinilam and (−)-Leucomidine B

J-B. Gualtierotti; D. Pasche; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2014

Vol. 53 , num. 37, p. 9926-9930.

DOI : 10.1002/anie.201405842

Triple Role of Phenylselenonyl Group Enabled a One-Pot Synthesis of 1,3-Oxazinan-2-ones From α-Isocyanoacetates, Phenyl Vinyl Selenones, and Water

T. Buyck; Q. Wang; J. Zhu 

Journal of the American Chemical Society

2014

Vol. 136 , num. 32, p. 11524-11528.

DOI : 10.1021/ja506031h

Chiral Phosphoric Acid-Catalyzed Enantioselective Three- Component Aza-Diels-Alder Reactions of Aminopyrroles and Aminopyrazoles

J. Brioche; T. Courant; L. Alcaraz; M. Stocks; M. Furber et al. 

Advanced Synthesis & Catalysis

2014

Vol. 356 , num. 8, p. 1719-1724.

DOI : 10.1002/adsc.201400093

From Racemic to Enantioselective Total Synthesis of Trigonoliimines via Development of an Organocatalytic Enantioselective Michael Addition of α-Aryl-α-isocyanoacetate to Vinyl Phenyl Selenone

T. Buyck; Q. Wang; J. Zhu 

CHIMIA International Journal for Chemistry

2014

Vol. 68 , num. 4, p. 211-214.

DOI : 10.2533/chimia.2014.211

Phosphoric Acid Catalyzed Diastereo- and Enantioselective Synthesis of Substituted 1,3-Diaminotetralins

G. Dagousset; W. Erb; J. Zhu; G. Masson 

Organic Letters

2014

Vol. 16 , num. 9, p. 2554-2557.

DOI : 10.1021/ol500946w

Copper-catalyzed three-component synthesis of 5-acetamidoimidazoles from carbodiimides, acyl chlorides and isocyanides

G. Sapuppo; Q. Wang; D. Swinnen; J. Zhu 

Organic Chemistry Frontiers

2014

Vol. 1 , num. 3, p. 240.

DOI : 10.1039/c4qo00034j

Three-Component Povarov Reaction–Heteroannulation with Arynes: Synthesis of 5,6-Dihydroindolo[1,2‑a]quinolines

A. Bunescu; Q. Wang; J. Zhu 

Organic Letters

2014

Vol. 16 , num. 6, p. 1756-1759.

DOI : 10.1021/ol500447r

Multicomponent Domino Process: Rational Design and Serendipity

Q. Wang; J. Zhu 

Domino Reactions; Weinheim: Wiley-VCH, 2014. p. 579-610.

ISBN : 978-3-527-33432-2

NIS-Assisted Aza-Friedel-Crafts Reaction with α-Carbamoysulfides as Precursors of

N. George; M. Bekkaye; A. Alix; J. Zhu; G. Masson 

Chemistry – A European Journal

2014

Vol. 20 , num. 13, p. 3621-3625.

DOI : 10.1002/chem.201400117

Total Synthesis of (±)-Aspidophylline A

W. Ren; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2014

Vol. 53 , num. 7, p. 1818-1821.

DOI : 10.1002/anie.201310929

2013

Design and Synthesis of 16-Membered Cyclopeptides Active Against Vancomycin-resistant Enterococci (VRE)

J. Zhu 

CHIMIA International Journal for Chemistry

2013

Vol. 67 , num. 12, p. 916-920.

DOI : 10.2533/chimia.2013.916

Enantioselective Total Syntheses of Leuconolam–Leuconoxine–Mersicarpine Group Monoterpene Indole Alkaloids

Z. Xu; Q. Wang; J. Zhu 

Journal of the American Chemical Society

2013

Vol. 135 , num. 51, p. 19127-19130.

DOI : 10.1021/ja4115192

Iron Chloride-Catalyzed Three-Component Domino Sequences: Syntheses of Functionalized α-Oxy-N-acylhemiaminals and α-Oxyimides

F. Drouet; J. Zhu; G. Masson 

Advanced Synthesis & Catalysis

2013

Vol. 355 , num. 18, p. 3563-3569.

DOI : 10.1002/adsc.201300847

Palladium(II)-Catalyzed Cyclizative Cross-Coupling of ortho-Alkynylanilines with ortho-Alkynylbenzamides under Aerobic Conditions

B. Yao; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2013

Vol. 52 , num. 49, p. 12992-12996.

DOI : 10.1002/anie.201307738

Synthesis of Multifunctionalized 1,2,3,4-Tetrahydropyridines, 2,3-Dihydropyridin-4(1H)-ones, and Pyridines from Tandem Reactions Initiated by [5+1] Cycloaddition of N-Formylmethyl-Substituted Enamides to Isocyanides: Mechanistic Insight and Synthetic Application

C-H. Lei; D-X. Wang; L. Zhao; J. Zhu; M-X. Wang 

Chemistry – A European Journal

2013

Vol. 19 , num. 50, p. 16981-16987.

DOI : 10.1002/chem.201303221

Catalytic Enantioselective Michael Addition of α-Aryl-α-Isocyanoacetates to Vinyl Selenone: Synthesis of α,α-Disubstituted α-Amino Acids and (+)- and (−)-Trigonoliimine A

T. Buyck; Q. Wang; J. Zhu 

Angewandte Chemie International Edition

2013

Vol. 52 , num. 48, p. 12714-12718.

DOI : 10.1002/anie.201306663

Palladium-Catalyzed Through-Space C(sp3)-H and C(sp2)-H Bond Activation by 1,4-Palladium Migration: Efficient Synthesis of [3,4]- Fused Oxindoles

T. Piou; A. Bunescu; Q. Wang; L. Neuville; J. Zhu 

Angewandte Chemie International Edition

2013

Vol. 52 , num. 47, p. 12385-12389.

DOI : 10.1002/anie.201306532

Heteroannulation of arynes with N-aryl-α-aminoketones for the synthesis of unsymmetrical N-aryl-2,3-disubstituted indoles: an aryne twist of Bischler–Möhlau indole synthesis

A. Bunescu; C. Piemontesi; Q. Wang; J. Zhu 

Chemical Communications

2013

Vol. 49 , num. 87, p. 10284.

DOI : 10.1039/c3cc46361c

Zinc Bromide Promoted Coupling of Isonitriles with Carboxylic Acids To Form 2,4,5-Trisubstituted Oxazoles

Y. Odabachian; S. Tong; Q. Wang; M-X. Wang; J. Zhu 

Angewandte Chemie International Edition

2013

Vol. 52 , num. 41, p. 10878-10882.

DOI : 10.1002/anie.201305506

Tertiary Amines as Synthetic Equivalents of Vinyl Cations: Zinc Bromide Promoted Coupling of Propargylamines with α-Isocyanoacetamides To Give 2,4,5-Trisubstituted Oxazoles Initiated by an Internal Redox Process

Y. Odabachian; Q. Wang; J. Zhu 

Chemistry – A European Journal

2013

Vol. 19 , num. 37, p. 12229-12233.

DOI : 10.1002/chem.201302106

Synthetic Study towards Strictamine: The Oxidative Coupling Approach

W. Ren; N. Tappin; Q. Wang; J. Zhu 

Synlett

2013

Vol. 24 , p. 1941-1944.

DOI : 10.1055/s-0033-1339472

Ugi Four-Component Reaction of Alcohols: Stoichiometric and Catalytic Oxidation/MCR Sequences

F. Drouet; G. Masson; J. Zhu 

Organic Letters

2013

Vol. 15 , num. 11, p. 2854-2857.

DOI : 10.1021/ol401181a

Synthesis of Iminonitriles by Oxone/TBAB-Mediated One-Pot Oxidative Three-Component Strecker Reaction

J-B. Gualtierotti; X. Schumacher; Q. Wang; J. Zhu 

Synthesis

2013

Vol. 45 , num. 10, p. 1380-1386.

DOI : 10.1055/s-0032-1316908