Total Synthesis – Multicomponent Reactions – Domino Process Catalytic Enantioselective Transformations
Latest News
June 2021 : iORC strikes again ! Our enantioselective total syntheses of (+)-Uleine is out in Helvetica Chimica Acta in a special issue dedicated to Prof. Kündig on the occasion of his 75th birthday : “Enantioselective Total Synthesis of (+)-Nordasycarpidone, (+)-Dasycarpidone and (+)-Uleine”
May 2021 : Congratulations to Jian & Hua for their publication in Nature Chemistry : “C–C bond activation enabled by dyotropic rearrangement of Pd(IV) species”
May 2021 : Our review on “Visible light photoredox-catalysed remote C–H functionalisation enabled by 1,5-hydrogen atom transfer (1,5-HAT)” is out in Chemical Society Reviews. Good job Weisi !
May 2021 : Congratulations to Alex for his recent publication is SCS Journal Chimia at the occasion of a special issue dedicated to the Laureates of 2020 SCS meeting ! Iron-Catalysed Remote C(sp3)-H Azidation of O-Acyl Oximes and N-Acyloxy Imidates
May 2021 : Congratulations to Yu-Ping & Hua for their publication in JACS : Catalytic Enantioselective Synthesis of Morpholinones Enabled by Aza-Benzilic Ester Rearrangement
May 2021 : Welcome to Fenggang, our visiting scholar for the coming year ! Enjoy your stay in Switzerland !
April 2021 : Farewell Hua & Yuping ! Best of luck for your future career in China !
April 2021 : Welcome to Baochao, our new post-doc !
April 2021 : An eye-catching step of any given synthesis is the one that change the molecular topology. Our outlook showcasing 10 recent natural product total syntheses featuring such a domino process is now online in ACS Central Science: Natural Product Synthesis Enabled by Domino Processes Incorporating a 1,2-Rearrangement Step
March 2021 : Great synthetic effort by Guang, Nico & Cyril ! Our enantioselective total synthesis of Alstilobanine C and derivatives is now out in Angewandte : Enantioselective Total Synthesis of (+)‐Alstilobanine C, (+)‐Undulifoline and (‐)‐Alpneumine H Congratulations to the team !!!
February 2021 : Congratulations to Yu-Ping, Jian and Hua for their recent publication in Angewandte : “Catalytic Enantioselective Aminopalladation–Heck Cascade” !
January 2021 : Guang’s total synthesis of (-)-cepharamine, and (-)-sinoracutine has just been published in Nature Communications : “Unified divergent strategy towards the total synthesis of the three sub-classes of hasubanan alkaloids” Congratulations !
January 2021 : Congratulations to Yu-Ping, Jian and Hua for their recent publication in ACIE : “Catalytic Enantioselective Aminopalladation‐Heck Cascade“
November 2020 : Congratulations to Weisi for his recent publication in ACIE “Selective 1,2‐Aminoisothiocyanation of 1,3‐Dienes Under Visible Light Photoredox Catalysis” Great Job !
November 2020 : Warm welcome to Dan & Jing, the two new members of the lab.
September 2020 : Our Total Synthesis of (+)-1,2-Dehydroaspidospermidine, (+)-Condyfoline, and (–)-Tubifoline has been highlighted in Synfact as Synfact of the Month !
August 2020 : Great group outing with all the team ! More pictures here
Monthly Seminars & Exercice Sessions
About Jieping
Latest Publications
“Enantioselective Total Synthesis of (+)-Nordasycarpidone, (+)-Dasycarpidone and (+)-Uleine”
Bastien Delayre, Cédric Fung, Dr. Qian Wang and Prof. Jieping Zhu
in Helvetica Chimica Acta, ASAP (DOI : doi.org/10.1002/hlca.202100088)
C–C bond activation enabled by dyotropic rearrangement of Pd(IV) species
Dr. Jian Cao, Dr. Hua Wu, Dr. Qian Wang and Prof. Jieping Zhu
in Nature Chemistry, ASAP (DOI : doi.org/10.1038/s41557-021-00698-y)
Dr. Weisi Guo, Dr. Qian Wang and Prof. Jieping Zhu
in Chemical Society Reviews, ASAP (DOI : doi.org/10.1039/D0CS00774A)
Iron-Catalysed Remote C(sp3)-H Azidation of O-Acyl Oximes and N-Acyloxy Imidates
Alexandre Leclair, Rubén O. Torres-Ochoa, Dr. Qian Wang and Prof. Jieping Zhu
in Chimia, 2021, 329-332
Catalytic Enantioselective Synthesis of Morpholinones Enabled by Aza-Benzilic Ester Rearrangement
Dr. Yu-Ping He, Dr. Hua Wu, Dr. Qian Wang, and Prof. Jieping Zhu
in JACS, ASAP (DOI : doi.org/10.1021/jacs.1c03915)
Natural Product Synthesis Enabled by Domino Processes Incorporating a 1,2-Rearrangement Step
Bastien Delayre, Dr. Qian Wang and Prof. Jieping Zhu
in ACS Central Science, ASAP (DOI : 10.1021/acscentsci.1c00075 )
Enantioselective Total Synthesis of (+)‐Alstilobanine C, (+)‐Undulifoline and (‐)‐Alpneumine H
Dr. Guang Li, Dr. Nicolas Gaeng, Dr. Cyril Piemontesi, Dr. Qian Wang, and Prof. Jieping Zhu
in Angewandte, ASAP (DOI : doi.org/10.1002/anie.202103580 )
Catalytic Enantioselective Aminopalladation–Heck Cascade
Dr. Yu-Ping He, Dr. Jian Cao, Dr. Hua Wu, Dr. Qian Wang, and Prof. Jieping Zhu
in Angewandte, ASAP (DOI : doi.org/10.1002/anie.202016001)
Dr. Guang Li, Dr. Qian Wang, and Prof. Jieping Zhu
in Nature Communications, ASAP (DOI: doi.org/10.1038/s41467-020-20274-1)
Catalytic Enantioselective Aminopalladation‐Heck Cascade
Dr. Yu-Ping He, Dr. Jian Cao, Dr. Hua Wu, Dr. Qian Wang, and Prof. Jieping Zhu
in Angewandte, ASAP (DOI: doi.org/10.1002/anie.202016001)
Selective 1,2‐Aminoisothiocyanation of 1,3‐Dienes Under Visible Light Photoredox Catalysis
Dr. Weisi Guo, Dr. Qian Wang, and Prof. Jieping Zhu
in Angewandte, ASAP (DOI: doi.org/10.1002/anie.202014518)
Palladium-Catalyzed Multicomponent Synthesis of Fully Substituted Alkylidene Furanones
Dr. Ángel Rentería-Gómez, Dr. Rubén O. Torres-Ochoa, Dr. Rocío Gámez-Montaño, Dr. Qian Wang, and Prof. Jieping Zhu
in Organic Letters, ASAP (DOI : doi.org/10.1021/acs.orglett.0c02578)
Dr. Jia-Chen, Dr. Qian Wang and Prof. Jieping Zhu
in Angewandte, ASAP (DOI : doi.org/10.1002/anie.202007548)
Rémi Andres, Dr. Qian Wang and Prof. Jieping Zhu
in JACS, Just accepted (DOI : doi.org/10.1021/jacs.0c05804)
Synthesis of Benzo[a]carbazoles via Visible Light‐Induced Cycloaromatization
Dr. Bo Yao, Dr. Qian Wang and Prof. Jieping Zhu
in Helv. Chim. Acta, ASAP (DOI : doi.org/10.1002/hlca.202000106)
Bastien Delayre†, Dr. Cyril Piemontesi†, Dr. Qian Wang and Prof. Jieping Zhu
in Angewandte, ASAP (DOI : doi.org/10.1002/anie.202005380)
Enantioselective Benzilic Ester Rearrangement
Dr. Hua Wu, Dr. Qian Wang and Prof. Jieping Zhu
in Angewandte, ASAP (DOI : doi.org/10.1002/anie.202001258)
Group Pictures 2010 – 2020
Fumehoods and lab equipment @ LSPN
Social Events & Group Outings