2023
J. Simões, G. Wagnières, S. Sarpaki, V. Sol, B. Therrien, “Porphyrin Metalla-Assemblies Coupled to Cellulose Nanocrystals for PDT and Imaging Applications”, J. Porphyrins and Phthalocyanines, 27, pp 1 – 14, 2023.
V. Pevná, G. Wagnières, D. Jancura, V. Huntošová, “Effect of photobiomodulation on Protein Kinase Cδ, cytochrome c and mitochondria in U87 MG cells”, Cells, 12, pp 1-16, 2023.
2022
D. Macabrey, J. Joniová, Q. Gasser, C. Bechelli, A. Longchamp, S. Urfer, M. Lambelet, G. Wagnières, S. Déglise and F. Allagnat, “Sodium Thiosulfate, a source of Hydrogen Sulfide, stimulates endothelial cell proliferation”, Frontiers in Cardiovascular Medicine, 9, 2022.
V. Pevna, D. Horvath, G. Wagnieres, V. Huntosova, “Photobiomodulation and Photodynamic Therapy-Induced Switching of Autophagy and Apoptosis in Human Dermal Fibroblasts”, J. Photochem. Photobiol. B Biol., 234, 112539, pp 1 – 10, 2022.
A. Gregor, S. Sase, G. Wagnieres, “Optimization of the distance between cylindrical light distributors used for interstitial light delivery in biological tissues”, Photonics, 9(597), pp 1 – 18, 2022.
J. Joniova and G. Wagnières, “The chicken embryo chorioallantoic membrane as an in vivo model for photodynamic therapy”, Methods in Molecular Biology, 2451, pp 107 – 125; 2022.
M. Jain, J. Bouilloux, I. Boreggo, S. Cook, H. van den Bergh, N. Lange, G. Wagnieres, M.-N. Giraud”, “Cathepsin B cleavable-polymeric photosensitizer prodrug for selective photodynamic therapy: In Vitro Studies”, Pharmaceuticals, 15(564), pp 1 – 16, 2022.
G. Croizat, A. Gregor, J. Joniova, E. Gerelli, G. Wagnières, “Identification of excimer delayed fluorescence by Protoporphyrin IX: a novel access to local chromophore concentration?”, J. Photochemistry & Photobiology, B: Biology, 209, 2022.
2021
V. Pevna, G. Wagnières, V. Huntosova, “Autophagy and apoptosis induced in U87 MG glioblastoma cells by hypericin-mediated photodynamic therapy can be photobiomodulated with 808 nm light”, Biomedicines, 9(1703), pp 1 – 17, 2021.
J. Joniova, C. Kazemiraad, E. Gerelli, G. Wagnieres, “Stimulation and homogenization of the protoporphyrin IX endogenous production by photobiomodulation to increase the potency of photodynamic therapy”, Journal of Photochemistry & Photobiology, B: Biology, 225, 2021.
M. Scholz, G. Croizat, J. Pšencík, R. Dedic, S. Nonell and G. Wagnieres, “Understanding delayed fluorescence and triplet decays of Protoporphyrin IX under hypoxic conditions”, Photochemical and Photobiological Sciences, 20(7), pp 843 – 857, 2021.
G. D. Kymionis; J. Kim, MD; M. Petrelli; M. A. Grentzelos; K. Hashemi; G. Wagnières, “Intraocular lens refractive index and its impact on external surface reflections”, Journal of Refractive Surgery, 37(6), pp 398 – 402, 2021.
V. Huntosova, D. Horvath, R. Seliga and G. Wagnieres, ” Influence of oxidative stress during time-resolved oxygen detection by [Ru(Phen)3]2+ in vivo and in vitro”, Molecules, 26(2), 495, pp 1 – 24, 2021.
2020
E. Gerelli, G. Wagnières, J. Joniova, “Stimulation of the oxygen consumption by photobiomodulation in the chicken embryo chorioallantoic membrane during hypoxia”, TBIO, 2020
J. Joniova and G. Wagnières, “Catechin reduces phototoxic effects induced by protoporphyrin IX-based PDT in the chick embryo chorioallantoic membrane”, J. Biomedical Optics, 25(6), 063807, 1-9, 2020.
S. Ali, F. Zhou, B. Braden, A. Bailey, S. Yang, G. Cheng, P. Zhang, X. Li, M. Kayser, R. Soberanis-Muku, S. Albarqouni, X. Wang, Ch. Wang, S. Watanabe, I. Oksuz, Q. Ning, S. Yang, M. Khan, X. Gao, S. Realdon, M. Loshchenov, J. Schnabel, J. East, G. Wagnieres, V. Loschenov, E. Grisan, Ch. Daul, W. Blondel, and J. Rittscher, “An objective comparison of detection and segmentation algorithms for artefacts in clinical endoscopy”, Scientific Reports 10(1), 2748, 2020.
S. Sun, Y. Yang, M. Chen, Li Wang, H. Pan, X. Zhang, G. Wagnières, Y. Mohammad, E. Barreiro, G. Pirozzolo, P. J. Villeneuve, P. Zhan, B. Wan, “Comparison of autofluorescence and white-light bronchoscopies performed with the Elvis Lucera Spectrum for the detection of bronchial cancers: a meta-analysis”, Trans. Lung Cancer Res 9(1),23-32, 2020.
M. Zellweger, Y. Xiao, M. Jain, M.-N. Giraud, A. Pitzschke, M. de Kalbermatten, E. Berger, H. van den Bergh, S. Cook and G. Wagnières, “Optical Characterization of an Intra-Arterial Light and Drug Delivery System for Photodynamic Therapy of Atherosclerotic Plaque”, Applied Sciences, 10(12), 4304, pp 1-11, 2020.
G. Croizat, A. Gregor, E. Gerelli, J. Joniova, M. Scholz, G. Wagnières, “A general framework for non-exponential Delayed Fluorescence and Phosphorescence decay analysis, illustrated on Protoporphyrin IX“, Journal of Photochemistry & Photobiology, B: Biology, 209, 111887, 2020.
2019
S. Ali, F. Zhou, Ch Daul, B. Breden, A. Bailey, S. Realdon, J. East, G. Wagnières, V. Loschenov, E. Grisan, W. Blondel, J. Rittscher, “Endoscopy artifact detection (EAD 2019) challenge dataset, arXiv, 2019.
J. Joniova and G. Wagnières, “The chicken embryo chorioallantoic membrane as an in vivo model for photodynamic therapy”, in press.
S. Cavin, T. Riedel, P. Rosskopfova, M. Gonzalez, G. Baldini, M. Zellweger, G. Wagnières, P. Dyson, H.-B. Ris, Th. Krueger, J. Y. Perentes, “Vascular-targeted low dose photodynamic therapy stabilizes tumor vessels by modulating pericyte contractility”, Lasers in Surgery & Medicine, 51, pp 550-561, 2019.
2018
J. Joniova, V. Kazikova, E. Gerelli, G. Bano and G. Wagnieres, “Measurements of the optical coefficients of the protoporphyrin IX endogenously producing yeast-based model in the visible and NIR”, J. Biomedical Optics, 23(7), 075001, 1-5, 2018.
V. Huntosova and G. Wagnières, “pO2 measurements in biological tissues by luminescence lifetime spectroscopy: Strategies to exploit or minimize phototoxic effects in tumors”, in: Quenched-phosphorescence Detection of Molecular Oxygen: Applications in Life Sciences, The Royal Society of Chemistry, Chapter 15, pp. 298-318, 2018.
L. Blascakova, D. Horvath, D. Belej, G. Wagnieres, P. Miskovsky, D. Jancura and V. Huntosova, “Hypericin cross barriers of the chicken chorioallantoic membrane model when delivered in low-density lipoproteins”, Photodiagnosis and Photodynamic Therapy, 23, pp 306-313, 2018.
2017
S. Cavin, X. Wang, C. Francioli, M. Zellweger, M. Gonzalez, M. Bensimon, G. Wagnières, Th. Krueger, H.-B. Ris, J. Y. Perentes, “Interstitial fluid pressure: a novel biomarker to monitor photo-induced drug uptake in tumor and normal tissues”, Lasers in Surg Med, 49(8), pp 773-780, 2017.
M. Zellweger, M. Jain, M.-N. Giraud, A. Pitzschke, M. de Kalbermatten, E. Berger, H. van den Bergh, S. Cook and G. Wagnières, “Design and Characterization of an intra-arterial light and drug delivery system for photodynamic therapy of atherosclerotic plaque”, submitted.
D. Belej, Z. Jurasekova, M. Nemergut, G. Wagnieres, D. Jancura and V. Huntosova, “Negligible interaction of [Ru(Phen)3]2+ with human serum albumin makes it promising for a reliable in vivo assessment of the tissue oxygenation”, Journal of Inorganic Biochemistry, 174, pp 37-44, 2017.
A. Pitzschke, J. Bertholet, B. Lovisa, M. Zellweger G. Wagnieres, “Determination of the radiance of cylindrical light diffusers: design of a one-axis charge-coupled device camera-based goniometer setup”, J. Biomed. Opt., 22(3), 035004, 1-9, 2017.
M. Jain, M. Zellweger, G. Wagnières, H. van den Bergh, S. Cook and M.-N. Giraud, “Photodynamic therapy for the treatment of atherosclerotic plaque: lost in translation?”, Cardiovascular Therapeutics, 35(2), pp 1-14, 2017.
M. Zellweger, C.-A. Porret, N. Lange, P. Jichlinski, H. van den Bergh, G. Wagnières, “PDT of non-muscle-invasive bladder cancer with Hexylester Aminolevulinate: optimization of the illumination wavelengths by fluorescence spectroscopy and imaging”, Imaging in Photodynamic therapy, Editors: M. Hamblin and Y. Huang, pp 385-394, 2017.
V. Huntosova, E. Gerelli, D. Horvath and G. Wagnieres, “Measurement of pO2 by luminescence lifetime spectroscopy: A comparative study of the phototoxicity and sensitivity of [Ru(Phen)3]2+ and PdTCPP in vivo”, Journal of Biophotonics, 10(5), pp 708-717, 2017.
2016
M. Jain, M. Zellweger, A. Frobert, J. Valentin, H. van den Bergh, G. Wagnières, S. Cook, M.-N. Giraud, “Intra-arterial drug and light delivery for photodynamic therapy using Visudyne®: implication for atherosclerotic plaque treatment”, Front. Physiol., 7:400, 2016.
M. Atif, M. Zellweger, G. Wagnières, “Review of the role played by the photosensitizer’s photobleaching during photodynamic therapy”, J. Optoelectronics and Adv. Materials, 18 (3-4), pp 338 – 350, 2016.
J. Joniova, E. Gerelli, M. Zellweger and G. Wagnieres, “Optimization and characterization of the endogenous production of protoporphyrin IX in a yeast model”, Journal of Biomedical Optics, 21(12), 125008, pp 1-8, 2016.
V. Huntosova, E. Gerelli, M. Zellweger, G. Wagnières, “Effect of PpIX photoproducts formation on pO2 measurement by time-resolved delayed fluorescence spectroscopy of PpIX in solution and in vivo”, J. Photochem Photobiol B: Biol, 164, pp 49-56, 2016.
2015
X. Wang, F. Gronchi, M. Bensimon, Th. Mercier, L. Decosterd, G. Wagnières, E. Debefve, H.-B. Ris, I. Letovanec, S. Peters, J. Perentes, “Treatment of Pleural Malignancies by Photo-Induction Combined to Systemic Chemotherapy: Proof of concept on rodent lung tumors and feasibility study on porcine chest cavities”, Lasers in Surgery and Medicine, 47 (10), pp. 807-816, 2015.
M. Zellweger, C. Martoccia, M. Mengin, Ch. Iselin, H. van den Bergh, G. Wagnieres, “Study of the influence of OTC Vitamin Complements intake on urine fluorescence to optimize cancer detection by fluorescence cystoscopy”, J. Biomed. Opt., 20(6), 066011, pp 1-5, 2015.
A. Oueslati, B. Lovisa, J. perrin, G. Wagnières, H. van den Bergh, Y. Tardy, Hilal A. Lasuel, “Biophotomodulation suppresses alpha-synuclein-induced toxicity in a rat genetic model of Parkinson’s disease.”. PLoS ONE, 10(10), pp 1-13, 2015.
Y. Wang, X. Wang, M.‐A. Le Bitoux, G. Wagnieres, H. van den Bergh, M. Gonzalez, H.‐B. Ris, J. Y. Perentes, T. Krueger, “Fluence plays a critical role on the subsequent distribution of chemotherapy and tumor growth delay in murine mesothelioma xenografts pre-treated by photodynamic therapy”, Lasers Surg. Med., 47(4), pp 323-330, 2015.
A. Pitzschke, B. Lovisa, O. Seydoux, M. Haenggi, M. F. Oertel, M. Zellweger, Y. Tardy and G. Wagnieres, “Optical properties of rabbit brain in the red and NIR: Changes observed under in-vivo, post-mortem, frozen and formalin-fixed conditions”, J. Biomed. Opt., 20(2), 025006-1-9, 2015.
A. Pitzschke, B. Lovisa, O. Seydoux, M. Zellweger, M. Pfleiderer, Y. Tardy and G. Wagnieres, “Red and NIR light dosimetry in the human deep brain”, Physics in Medicine and Biology, 60, pp 2921–37, 2015.
2014
V. Huntosova, K. Stroffekova, G. Wagnieres, M. Novotova, Z. Nichtova and P. Miskovsky, “Endosomes: guardians against [Ru(Phen)3]2+ photo-action in endothelial cells during in vivo pO2 detection?”, Metallomics, 6(12), pp. 2279-2289, 2014.
J. Varchola, V. Huntosova, D. Jancura, G. Wagnieres, P. Miskovsky and G. Bánó, “Temperature and oxygen-concentration dependence of singlet oxygen production by RuPhen as detected with quasi-continuous excitation”, Photochem. Photobiol. Sci., 13 (12), pp 1781 – 1787, 2014.
C. Martoccia, M. Zellweger, B. Lovisa, P. Jichlinski, H. van den Bergh, G. Wagnieres, “Optical spectroscopy of the bladder washout fluid to optimize fluorescence cystoscopy with Hexvix®”, J. Biomed. Opt., 19(9), 097002, pp 1-6, 2014.
V. Huntosova, S. Gay, P. Nowak-Sliwinska, S. Kumar Rajendran, M. Zellweger, H. van den Bergh, G. Wagnieres, ” In Vivo Measurement of Tissue Oxygenation by Time-resolved Luminescence Spectroscopy: Advantageous properties of dichlorotris(1,10-phenantroline)-Ruthenium(II) hydrate (Ru(Phen))”, J. Biomed. Opt., 19(7), 077004, 2014.
J. Y. Perentes, Y. Wang, X. Wang, E. Abdelnour, M. Gonzalez, L. Decosterd, G. Wagnieres, H. van den Bergh, S. Peters, H.-B. Ris, Th. Krueger, “Low-Dose Vascular Photodynamic Therapy Decreases Tumor Interstitial Fluid Pressure, which Promotes Liposomal Doxorubicin Distribution in a Murine Sarcoma Metastasis Model”, Translational oncology, 7(3), pp 393-399, 2014.
S. Gay, C. Martoccia, M. Zellweger, Q. Wang, G. Wagnieres, “Study of the stability of the 5-aminolevulinic acid tyrosine ester in aqueous solution”, Arkivoc, iii, pp 228 – 238, 2014.
G. Wagnières, P. Jichlinski, N. Lange, P. Kucera, and H. van den Bergh, “Detection of Bladder Cancer by Fluorescence Cystoscopy: From Bench to Bedside – the Hexvix Story”, in: Handbook of Photomedicine; AE: M. R. Hamblin, Y.-Y. Huang, CRC Press (Taylor & Francis), pp 411-426, 2014.
2013
M. Vos, B. Lovisa, A. Geens, V. A. Morais, G. Wagnières, H. van den Bergh, A. Ginggen, B. De Strooper, Y. Tardy and P. Verstreken, “Near-Infrared 808 nm light boosts Complex IV-dependent respiration and rescues a Parkinson-related pink1 model”, Plos One, 8(11), e78562, 2013.
F. Piffaretti, M. Zellweger, B. Kasraee, J. Barge, D. Salomon, H. van den Bergh, G. Wagnières, “Correlation Between Protoporphyrin IX Fluorescence Intensity, Photobleaching, Pain and Clinical Outcome of Actinic Keratosis Treated by Photodynamic Therapy “, Dermatology, 227(3), pp 214-225, 2013.
J. Barge, Th. Glanzmann, M. Zellweger, D. Salomon, H. van den Bergh, G. Wagnières, “Correlations between photoactivable porphyrins’ fluorescence, erythema and the pain induced by PDT on normal skin using ALA-derivatives”, PD&PDT, 10, pp 683-693, 2013.
2012
F. Piffaretti, J.-P. Ballini, R. Perotti, M. Zellweger, E. Vezzola, M. Sickenberg, G. Wagnières “Reflectance Imaging of the Human Retina at 810 nm does not suffice to optimize the Parameters of Hydrodynamic Rebalancing Laser Treatment”. Journal of Biomedical Optics, 17(11), 116027-1-10, 2012.
F. Piffaretti, A. M. Novello, R. Senthil Kumar, E. Forte, C. Paulou, P. Nowak-Sliwinska, H. van den Bergh, G. Wagnières “Real-time, in vivo measurement of tissular pO2 through the delayed fluorescence of endogenous protoporphyrin IX during photodynamic therapy”. Journal of Biomedical Optics, 17(11), 115007-1-9, 2012.
J. P. Johnpeter, F. Schmitt, E. Denoyelle-Di-Muro, G. Wagnières, L. Juillerat-Jeanneret, B. Therrien, “Photoactive sawhorse-type diruthenium tetracarbonyl complexes”, Inorganica Chimica Acta, 393, pp 246-251, 2012.
R. Senthil Kumar, H. van den Bergh, G. Wagnières, “Probing the interaction between Surfactant-Cobalt(III) complex with Bovine Serum Albumin“, Journal of Solution Chemistry, 41, pp 294-306, 2012.
P. Nowak-Sliwinska, M. Storto, T. Cataudella, J.-P. Ballini, R. Gatz, M. Giorgio, H. van den Bergh, S. Plyte, G. Wagnières, “Angiogenesis inhibition by the maleimide-based small molecule GNX-686 “, Microvascular Research, 83 (2) , pp. 105-110, 2012.
2011
P. Nowak-Sliwinska, Käuper P, van den Bergh H, Wagnières G, “Study of the pO2-sensitivity of the dendrimeric and free forms of Pd-meso-tetra(4-carboxyphenyl)porphyrin, incorporated or not in chitosan-based nanoparticles“, Chimia. 65(9), pp 691-695, 2011.
R. Senthil Kumar, Preethy Paul, A. Riyasdeen, Georges Wagnieres, Hubert van den Bergh, M.A. Akbarsha, S. Arunachalam, “Human serum albumin binding and cytotoxicity studies of surfactant-cobalt(III) complex containing 1,10-phenanthroline ligand“, Colloids and Surfaces B: Biointerfaces, 86, pp 35-44, 2011.
P. Nowak-Sliwinska, van Beijnum JR, Casini A, Nazarov A, Wagnières G, van den Bergh H, Dyson PJ, Griffioen AW. “Organometallic ruthenium (II)-arene compounds with anti-angiogenesis activity“, Journal of Medicinal Chemistry, 54, pp 3895-3902, 2011.
F. Piffaretti, K. Santhakumar, E. Forte, H. van den Bergh and G. Wagnieres, ” Optical fiber-based setup for in vivo measurement of the delayed fluorescence lifetime of oxygen sensors”, Journal of Biomedical Optics 16(3), 037005 1-11, 2011.
L. Favre, F. Borle, D. Velin, D. Bachmann, H. Bouzouréne, G. Wagnières, H. van den Bergh, P. Ballabeni, T. Gabrecht, P. Michetti, S. Schreiber, M.-A. Ortner, “Low dose endoluminal photodynamic therapy improves murine T cell-mediated colitis”, Endoscopy, 43, pp 1 – 13, 2011.
2010
B. Lovisa, P. Jichlinski, B.-C. Weber, D. Aymon, H. van den Bergh, G. Wagnières, ” High-magnification vascular imaging to reject false positive sites in situ during Hexvix® fluorescence cystoscopy”, J. Biomed. Optics, 15(5), pp 051606 1-8, 2010.
P. Nowak-Sliwinska, G. Wagnieres, H. van den Bergh and A. W. Griffioen, “Angiostasis induced vascular normalization can improve photodynamic therapy”, Cell. Mol. Life Sci., 67, pp 1559-1560, 2010.
C. Cheng, E. Debefve, A. Haouala, S. Andrejevic-Blant, T. Krueger, J.-P. Ballini, S. Peters, L. Decosterd, H. van den Bergh, G. Wagnières, J. Perentes H.-B. Ris, “Photodynamic therapy selectively enhances Liposomal Doxorubicin Uptake in Sarcoma Tumors to Rodent Lungs”, Lasers Surg. Med., 42, pp 391 – 399, 2010.
F. Schmitt, L. Lagopoulos, P. Käuper, N. Rossi, N. Busso, J. Barge, G. Wagnières, C. Laue, Ch. Wandrey, L. Juillerat-Jeanneret, “Chitosan-based nanogels for selective delivery of photosensitizers to macrophages and improved retention in and therapy of articular joints”, Journal of Controlled Release, 144(2), pp 242-250, 2010.
S. Lim, C. Thivierge, P. Nowak-Sliwinska, J. Han, H. van den Bergh, G. Wagnières, K. Burgess, H. Lee, “In Vitro and In Vivo Photocytotoxicity of Boron Dipyrromethene Derivatives for Photodynamic Therapy”, Journal of Medicinal Chemistry, 53(7), pp 2865 – 74, 2010.
S. Lim, P. Nowak-Sliwinska, F. A. Kamarulzaman, H. van den Bergh, G. Wagnières, H. Lee, “The neovessel occlusion efficacy of 15-hydroxypurpurin-7-lactone dimethyl ester induced with photodynamic therapy”, Photochemistry and Photobiology, 86(2), pp 397 – 402, 2010.
P. Nowak-Sliwinska, J.-P. Ballini, G. Wagnières, H. van den Bergh, “Processing of Fluorescence Angiograms for the Quantification of Vascular Effects Induced by Anti-angiogenic Agents in the CAM model”, Microvascular Research, 79, pp 21–28, 2010.
2009
Th. Glanzmann, M. Zellweger, F. Borle, R. Conde, A. Radu, J.-P. Ballini, Y. Jaquet, R. Pilloud, H. van den Bergh, Ph. Monnier, S. Andrejevic-Blant and G. Wagnières, “Assessment of a sheep animal model to optimize photodynamic therapy in the oesophagus”, Lasers in Surg. & Med. (41), pp 643-652, 2009.
P. Uehlinger, T. Gabrecht, Th. Glanzmann, J.-P. Ballini, A. Radu, S. Andrejevic Blant, Ph. Monnier, and G. Wagnières “In vivo time-resolved spectroscopy of the human bronchial early cancer autofluorescence”, J. Biomedical Optics, 14(2), 024011, pp 1-9, 2009.
T. Gabrecht, B. Lovisa, H. van den Bergh, G. Wagnières, “Autofluorescence bronchoscopy: Quantification of inter-patient variations of fluorescence intensity”, Lasers in Medical Sciences, 24(1), pp 45 – 51, 2009.
2008
P. Jichlinski, B. Lovisa, C. Erling, D. Aymon, H. Van Den Bergh, G. Wagnieres, “Fluorescence cystoscopy: Perspective in clinical practice and research”, Urologe – Ausgabe A 47 (8), pp. 975-977, 2008.
N. Dögnitz, D. Salomon, M. Zellweger, J-.P. Ballini, T. Gabrecht, N. Lange, H. van den Bergh, G. Wagnières, “Comparison of ALA- and ALA hexyl-ester-induced PpIX depth distribution in human skin carcinoma”, J. Photochem. Photobiol. B: Biol, 93(3), pp 140 – 148, 2008.
D. Hüttenberger, T. Gabrecht, G. Wagnières, B. Weber, A. Linder, H.-J. Foth, L. Freitag, “Autofluorescence detection of tumors in the human lung: Spectroscopical measurements in situ, in an in vivo model and in vitro“, Photodiagnosis and Photodynamic Therapy, pp 139 – 147, 2008.
T. Gabrecht, Radu A, Grosjean P, Weber BC, Reichle G, Freitag L, Monnier Ph, van den Bergh H, Wagnières G, “Improvement of the Specificity or Cancer Detection by Autofluorescence Imanging in the Tracheo-Bronchial Tree using backscattered Violet Light”, PD&PDT, 5, pp 2 – 9, 2008.
E. Debefve, B. Pegaz, H. van den Bergh, G. Wagnières, N. Lange, J.–P. Ballini, “Video monitoring of neovessel occlusion induced by photodynamic therapy with verteporfin (Visudyne®), in the CAM model”, Angiogenesis, 11, pp 235 – 243, 2008.
V. Vallinayagam, F. Schmitt, J. Barge, G. Wagnières, V. Wenger, R. Neier, L. Juillerat-Jeanneret, “Glycoside esters of aminolevulinic acid for targeted photodynamic therapy of cancer”, Bioconjugate Chemistry, 19(4), pp 821 – 39, 2008.
2007
B. Lovisa, T. Gabrecht, S. Andrejevic, P. Grosjean, A. Radu, Ph. Monnier, H. van den Bergh, G. Wagnières, “Improvement of the Contrast in Cancer Detection by Autofluorescence Bronchoscopy using a narrow spectral violet Excitation: A preliminary study”, Biomedical Signal Processing and Control, 2(3), pp 234-238, 2007.
T. Gabrecht, B. Lovisa, F. Borle, G. Wagnières, “Design of an Endoscopic Optical Reference to be used for Autofluorescence Bronchoscopy with the DAFE system”, Phys. Med. Biol., 52, pp 163-171, 2007.
T. Gabrecht, A. Radu, M. Zellweger, B. Lovisa, D. Goujon, P. Grosjean, H. van den Bergh, Ph. Monnier, G. Wagnières, “Autofluorescence bronchoscopy: clinical experience with an optimized system in head and neck cancer patients”, Med. Laser Appl., 22, pp 185–192, 2007.
T. Gabrecht, S. Andrejevic-Blant, G. Wagnières, “Blue-violet excited Autofluorecence Spectroscopy and Imaging of Normal and Cancerous Human Bronchial Tissue after Formalin-Fixation”, Photochem. Photobiol, 83, pp 450 – 458, 2007.
T. Gabrecht, Th. Glanzmann, L. Freitag, B.-C. Weber, H. van den Bergh, G. Wagnières, “Optimised autofluorescence spectroscopy using additional backscattered red light”, J. Biomed. Opt., 12, 064016, 2007.
2006
P. Uehlinger, J-P. Ballini, H. van den Bergh and G. Wagnières, “On the Role of Iron and one of its Chelating Agents in the Production of Protoporphyrin IX Generated by 5-Aminolevulinic Acid and its Hexyl Ester Derivative Tested on an Epidermal Equivalent of Human Skin”, Photochemistry&Photobiology, 82, pp 1069-76, 2006.
B. Pegaz, E. Debefve, J.-P. Ballini, G. Wagnières, S. Spaniol, V. Albrecht, D. Scheglmann, N. Nifantiev, H. van den Bergh, Y. Konan-Kouakou, “Photothrombic activity of m-THPC-loaded liposomal formulations: pre-clinical assessment on chick chorioallantoic membrane model”, European Journal of Pharmaceutical Sciences, 28, pp 134-140, 2006.
I. Opitz, T. Krueger, Y. Pan, H.-J. Altermatt, G. Wagnières, H.-B. Ris, “Preclinical comparison of mTHPC and verteporphin for intraoperative photodynamic therapy of malignant pleural mesothelioma”, Eur. Surg. Res., 38, pp 333 – 339, 2006.
2005
B. Pegaz, E. Debefve, J.-P. Ballini, G. Wagnières, S. Spaniol, V. Albrecht, D. Scheglmann, N. Nifantiev, H. van den Bergh, Y. Konan, “Preclinical evaluation of a novel water-soluble chlorin E6 derivative (BLC 1010) as photosensitizer for the closure of the neovessels”, Photochem. Photobiol., 81, pp 1505-1510, 2005.
A. Radu, P. Grosjean, Y. Jaquet, R. Pilloud, G. Wagnières, H. van den Bergh and Ph. Monnier, “Photodynamic therapy and endoscopic mucosal resection as minimally invasive approaches for the treatment of early esophageal tumors: Pre-clinical and clinical experience in Lausanne”, 2(1), Photodiag. Photodyn. Ther., pp 35-43, 2005.
A. Degen, T. Gabrecht, G. Wagnières, R. Caduff, B. Imthurn, P. Wyss, “Influence of the menstrual cycle on aminolevulinic acid induced protoporphyrin IX fluorescence in the endometrium: in vivo study”, Lasers in Surg. Med., 36(3), pp 234-237, 2005.
Th. Stepinac, S. Chamot, E. Rungger-Brändle, P. Ferrez, J.-L. Munoz, H. van den Bergh, Ch. Riva, C. Pournaraz, and G. Wagnières, “Light-Induced Retinal Vascular Damage by Pd-porphyrin Luminescent Oxygen Probes”, Invest. Ophthalmol. Vis. Sci., 46(3), pp 956-966, 2005.
2004
S. Andrejevic-Blant, A. Major, F. Lüdicke, J.-P. Ballini, G. Wagnières, H. van den Bergh and M.-F. Pelte, “Time-dependent hexaminolevulinate induced protoporphyrin IX distribution after topical application in patients with cervical intraepithelial neoplasia: A fluorescence microscopy study”, Lasers in Surg. Med, 35, pp 276 – 283, 2004.
G. Wagnières, “Méthodes optiques de mesure de la concentration d’oxygène tissulaire pour la photothérapie dynamique”, Photoniques, vol 14, pp 1 – 5, 2004.
A. Degen, T. Gabrecht, L. Mosimann, M. Fehr, R. Hornung, V. Schwarz, Y. Tadir, R. Steiner, G. Wagnières, P. Wyss, “Photodynamic endometrial ablation for the treatment of dysfunctional uterine bleeding: A preliminary report”, Lasers Surg. Med., 34, pp 1-4, 2004.
2003
P. Wyss, R. Caduff, Y. Tadir, A. Degen, G. Wagnières, V. Schwarz, U. Haller, M. Fehr, “Photodynamic endometrial ablation: Morphological study”, Lasers in Surgery and Medicine, 32(4), pp 305-309, 2003.
G. Wagnières, A. Mcwilliams and S. Lam, “Lung cancer Imaging by autofluorescence bronchoscopy”, in: Handbook of Biomedical Fluorescence, M.-A. Mycek and B. Pogue Editors, Marcel Dekker Inc., pp 361-396, 2003.
F. Lüdicke, T. Gabrecht, N. Lange, G. Wagnières, H. van den Bergh, L. Berclaz and A. Major, “Photodynamic diagnosis of ovarian cancer using aminolevulinic acid hexylester: A preclinical study”, Brit. J. of Cancer, 88(11), pp 1780-1784, 2003.
F. Borle, A. Radu, G. Wagnières, H. van den Bergh, Ph. Monnier, “Evaluation of the photosensitizer Tookad for photodynamic therapy on the Syrian golden hamster cheek pouch model: Light dose, drug dose and drug-light interval effects”, Photochem. Photobiol, 78(4), pp 377 – 383, 2003.
F. Borle, A. Radu, G. Wagnières, H. van den Bergh , Ph. Monnier “Evaluation of the photosensitizer Tookad on the Syrian golden hamster cheek pouch model: Response of photodynamic therapy on chemically induced squamous cell carcinoma versus healthy mucosae”, Brit. J. Cancer, 89(12), pp 2320 – 2326, 2003.
A. Radu, R. Conde, G. Wagnières, Ch. Fontolliet, H. van den Bergh, Ph. Monnier, “Mucosal ablation with photodynamic therapy in the esophagus: Optimization of Light Dosimetry in the sheep model”, Gastrointestinal Endoscopy, 57(7), pp 897 – 905, 2003.
Th. Stepinac, Ch. Felley, P. Jornod, N. Lange, G. Wagnières, Ch. Fontolliet, H. van den Bergh, Ph. Monnier, P. Michetti, G. Dorta, “Endoscopic Fluorescence Detection of Dysplasia and Early Adenocarcinoma in Barrett’s Esophagus after Administration of 5-Aminolevulinic Acid: a controlled Clinical Trial”, Endoscopy, 35(8), pp 663-668, 2003.
D Goujon, M Zellweger, A Radu, P Grosjean, B-C Weber, H van den Bergh, Ph monnier, G. Wagnières. In vivo autofluorescence imaging of early cancers in the human tracheo-bronchial tree with a spectrally optimized system. J Biomed Opt, 8(1), pp 17-25, 2003.
2002
S. Andrejevic Blant, Th. Glanzmann, J.-P. Ballini, G. Wagnières, H. van den Bergh, Ph. Monnier, “Uptake and localization of mTHPC (Foscan®) and its 14C-labeled form in normal and tumor tissues of hamster squamous cell carcinoma model: a comparative study”, British Journal of Cancer, 87(12), pp 1470-1478, 2002.
Th. Stepinac, P. Grosjean, A. Woodtli, P. Monnier, H. van den Bergh, G. Wagnières, “Optimization of the Diameter of a Radial Irradiation Device for Photodynamic Therapy in the Esophagus”, Endoscopy, 34(5), pp 411-415, 2002.
C. Wilder-Smith, P. Wilder-Smith, P. Grosjean, H. van den Bergh, A. Woodtli, Ph. Monnier, G. Dorta, F. Meister, G. Wagnières, “Photoeradication of Helicobacter pylori using 5-aminolevulinic acid: preliminary human studies”, Laser in Surgery and Medicine, 31(1), pp 18-22, 2002.
2001
S. Andrejevic Blant, P. Grosjean, J.-P. Ballini, G. Wagnières, H. van den Bergh, Ch. Fontolliet and Ph. Monnier, “Localisation of tetra(m-hydroxyphenyl)chlorin (Foscan@) in human healthy tissues and squamous cell carcinomas of the upper aero-digestive tract, the esophagus and the bronchi: a fluorescence microscopy study”, J. Photochem. Photobiol. B: biol., 61, pp 1-9, 2001.
N. Lange, J.-P. Ballini, G. Wagnières and H. van den Bergh, “A new Drug-Screening Procedure for Photosensitizing Agents used in Photodynamic Therapy of Choroidal Neovascularization”, Investigative Ophthalmology & Visual Science, 42(1), pp 38-46, 2001.
M. Zellweger, P. Grosjean, D. Goujon, Ph. Monnier, H. van den Bergh and G. Wagnières, “In vivo autofluorescence spectroscopy of human bronchial tissue to optimize the detection and imaging of early cancers”, J. of Biomedical Optics, 6(1), pp 41-51, 2001.
M. Zellweger, D, Goujon, M. Forrer, H. van den Bergh and G. Wagnières, “Absolute autofluorescence spectra of healthy bronchial tissue in vivo”, Applied Optics, 40(22), pp 3784-3791, 2001.
2000
Th. Glanzmann, M. Forrer, S. Andrejevic Blant, A. Woodtli, P. Grosjean, D. Braichotte, H. van den Bergh, Ph. Monnier and G. Wagnières, “Pharmacokinetics and Pharmacodynamics of tetra(m-hydroxyphenyl)chlorin in the Hamster Cheek Pouch Tumor Model: Comparison with Clinical Measurements”, J. Photochem. Photobiol. B: Biol., 57, pp 22-32, 2000.
S. Andrejevic Blant, J.-P. Ballini, H. van den Bergh, Ch. Fontolliet, G. Wagnières and Ph. Monnier, “Time dependent biodistribution of tetra(m-hydroxyphenyl)chlorin and benzoporphyrin derivative monoacid ring A in the hamster model: comparative fluorescence microscopy study”, Photochem. Photobiol., 71(3), pp 333-340, 2000.
M. Zellweger, A. Radu, Ph. Monnier, H. van den Bergh and G. Wagnières, “In vivo pharmacokinetics of Lutetium Texaphyrin in the healthy and tumoral cheek pouch mucosa. Retention and selectivity properties”, J. Photochem. Photobiol. B: Biol., 55(1), pp 56-62, 2000.
A. Radu, G. Wagnières, H. van den Bergh, and Ph. Monnier, “Photodynamic therapy of early squamous cell cancers of the esophagus”, Gastrointestinal endoscopy Clin North America, 10(3), pp 439-460, 2000.
R. Bays, A. Woodtli, L. Mosimann, P. Wyss, G. Wagnières, U. Haller, H. van den Bergh, “A light distributor for photodynamic endometrial ablation”, Photomedicine in Gynecology and Reproduction; P. Wyss, Y. Tadir, B. Tromberg, U. Haller: Authors Editors, Karger, Basel, pp 227-233, 2000.
P. Uehlinger, M. Zellweger, G. Wagnières, L. Juillerat, H. van den Bergh and N. Lange, “5-Aminolevulinic acid and its derivatives: physical chemical properties and protoporphyrin IX formation in cultured cells”, J. Photochem. Photobiol. B:Biol., 54, pp 72-80, 2000.
1999
S. Iinuma, K. T. Schomacker, G. Wagnières, M. Rajadhyaksha, M. Bamberg, T. Momma and T. Hasan, “In vivo fluence rate and fractionation effects on tumor response and photobleaching: photodynamic therapy with two photosensitizers in an orthotopic rat tumor model”, Cancer Res (United States), 59(24), pp 6164-6170, 1999.
J. Mizeret, Th. Stepinac, M. Hansroul, A. Studzinski, H. van den Bergh and G. Wagnières, “Instrument for real-time endoscopic fluorescence lifetime imaging”, Rev. Sci. Instrum., 70(12), pp 4689-4701, 1999.
Th. Glanzmann, J.-P. Ballini, H. van den Bergh and G. Wagnières, “Time-resolved spectrofluorometer for clinical tissue characterization”, Rev. Sci. Instrum., 70(10), pp 4067-4077, 1999.
M. Zellweger, P. Grosjean, Ph. Monnier, H. van den Bergh and G. Wagnières, “Stability of the fluorescence measurement of Foscan® in the normal human oral cavity as an indicator of its content in early cancers of the esophagus and the bronchi”, Photochem. Photobiol, 69(5), pp 605-610, 1999.
N. Lange, P. Jichlinski, M. Zellweger, M. Forrer, A. Marti, L. Guillou, P. Kucera, G. Wagnières and H. van den Bergh, “Photodetection of early human bladder cancer based on the fluorescence of 5-aminolaevulinic acid hexylester-induced protoporphyrin IX: a pilot study”, Brit. J. Cancer, 80(1/2), pp 185-193, 1999.
A. Radu, P. Grosjean, Ch. Fontolliet, G. Wagnières, A. Woodtli, H. van den Bergh and Ph. Monnier, “Photodynamic Therapy for 101 Early Cancers of the Upper Aerodigestive Tract, the Esophagus, and the Bronchi: A single-Institution Experience”, Diagnostic and Therapeutic Endoscopy, 5, pp 145-154, 1999.
1998
G. Wagnières, W. Star and B. Wilson, “In vivo fluorescence spectroscopy and imaging for oncological applications”, Photochem. Photobiol., 68(5), pp 603-632, 1998.
G. Wagnières, Ch. Hadjur, P. Grosjean, D. Braichotte, J.-F. Savary, Ph. Monnier and H. van den Bergh, “Clinical evaluation of the cutaneous phototoxicity of 5, 10, 15, 20-tetra(m-hydroxyphenyl)chlorin”, Photochem. Photobiol., 68(3), pp 382-387, 1998.
Ch. Hadjur, N. Lange, J. Rebstein, Ph. Monnier, H. van den Bergh and G. Wagnières “Spectroscopic studies of photobleaching and photoproduct formation of meta(tetrahydroxyphenyl)chlorin (mTHPC) used in photodynamic therapy. The production of singlet oxygen by mTHPC”, J. Photochem. Photobiol. B: Biology, 45, pp 170-178, 1998.
A. Kienle, Th. Glanzmann, G. Wagnières, H. van den Bergh, “Investigation of two-layered turbid media with time-resolved reflectance”, Applied Optics, 37(28), pp 6852-6862, 1998.
Th. Glanzmann, Ch. Hadjur, M. Zellweger, P. Grosjean, M. Forrer, J.-P. Ballini, Ph. Monnier, H. van den Bergh, Ch. Lim and G. Wagnières, “Pharmacokinetics of Tetra(m-hydroxyphenyl)chlorin in Human Plasma and Individualized Light Dosimetry in Photodynamic Therapy”, Photochem. Photobiol., 67(5), pp 596-602, 1998.
N. Dögnitz and G. Wagnières, “Determination of Tissue Optical Properties by Steady State Spatial Frequency-domain Reflectometry”, Lasers in Med. Sci., 13, pp 55-65, 1998.
P. Grosjean, G. Wagnières, Ch. Fontolliet, H. van den Bergh and Ph. Monnier, “Clinical photodynamic therapy for superficial cancer in the oesophagus and the bronchi: 514 nm compared with 630 nm light irradiation after sensitization with Photofrin II”, Brit. J. of Cancer, 77(11), pp 1989-1995, 1998.
P. Westermann, Th. Glanzmann, S. Andrejevic, D. Braichotte, M. Forrer, G. Wagnières, Ph. Monnier, H. van den Bergh, J.-P. Mach and S. Folli, “Long circulating half-life and high tumor selectivity of the photosensitizer meta-tetrahydroxyphenylchlorin conjugated to polyethylene-glycol in nude-mice grafted with a human colon-carcinoma” Int. J. Cancer, 76(6), pp 842-850, 1998.
S. Andrejevic-Blant, A. Woodtli, G. Wagnières, Ch. Fontolliet, H. van den Bergh and Ph. Monnier, “Interstitial photodynamic therapy with tetra(m-hydroxyphenyl)chlorin: tumor versus striated muscle damage”, Int. J. of Radiation Oncology Biol. Phys., 42(2), pp 403-412, 1998.
J.-F. Savary, P. Grosjean, Ph. Monnier, Ch. Fontolliet, G. Wagnières, D. Braichotte and H. van den Bergh, “Photodynamic therapy of early squamous cell carcinomas of the eosophagus: a review of 31 cases”, Endoscopy, 30, pp 258-265, 1998.
A. Kienle, M. Patterson, N. Dögnitz, R. Bays, G. Wagnières and H. van den Bergh, “Noninvasive determination of the optical properties of two-layered turbid media”, Applied Optics, 37(4), pp 779-791, 1998.
1997
G. Wagnières, J. Mizeret, A. Studzinski and H. van den Bergh, “Frequency-Domain Fluorescence Lifetime Imaging for Endoscopic Clinical Cancer Photodetection: Apparatus Design and Preliminary Results”, J. of Fluorescence, 7(1), pp 75-83, 1997.
G. Wagnières, A. Studzinski and H. van den Bergh, “An endoscopic fluorescence imaging system for simultaneous visual examination and photodetection of cancers”, Rev. Sci. Instrum., 68(1), pp 203-212, 1997.
S. Andrejevic Blant, Ch. Hadjur, J.-P. Ballini, G. Wagnières, Ch. Fontolliet, H. van den Bergh and Ph. Monnier, “Photodynamic therapy of early squamous cell carcinoma with tetra(m-hydroxyphenyl chlorin: Optimal drug-light interval”, Brit. J. of Cancer, 76(8), pp 1021-1028, 1997.
G. Wagnières, S. Cheng, M. Zellweger, N. Utke, D. Braichotte, J.-P. Ballini and H. van den Bergh, “An optical phantom with tissue-like properties in the visible for use in PDT and fluorescence spectroscopy”, Phys. Med. Biol, 42, pp 1-12, 1997.
P. Jichlinski, G. Wagnières, M. Forrer, J. Mizeret, L. Guillou, F. Schmidlin, P. Graber, H. van den Bergh et H.-J. Leisinger, “Intérêt clinique de la cystoscopie à fluorescence dans la détection des carcinomes à épithélium de transition superficiels de la vessie”, Annales d’Urologie, 31(1), pp 43-48, 1997.
J. Mizeret, G. Wagnières, Th Stepinac and H. van den Bergh, “Endoscopic Tissue Characterization by Frequency-Domain Fluorescence Lifetime Imaging”, Lasers in Medical Science, 12(3), pp 209-217, 1997.
S. Andrejevic Blant, J.-F. Theumann, M. Forrer, G. Wagnières, H. van den Bergh and Ph. Monnier, “Wavelength-dependent effect of tetra(m-hydroxyphenyl)chlorin for photodynamic therapy in an “early” squamous cell carcinoma model”, Lasers in Medical Science, 12(3), pp 269-273, 1997.
Ch. Hadjur, G. Wagnières, F. Ihringer, Ph. Monnier and H. van den Bergh, “Production of free Radicals O2._ and .OH by Irradiation of the Photosensitizer Zinc(II) Phthalocyanine”, Journal of Photochem. Photobiol. B: Biology, 38, pp 196-202, 1997.
P. Jichlinski, G. Wagnières, M. Forrer, J. Mizeret, L. Guillou, M. Oswald, F. Schmidlin, P. Graber, H. van den Bergh et H.-J. Leisinger, “Clinical assessment of fluorescence cystoscopy during transurethral bladder resection in superficial bladder cancer”, Urological Research, 25, pp S3-S6, 1997.
Ch. Hadjur, G. Wagnières, Ph. Monnier and H. van den Bergh, “EPR and Spectrophotometric studies of free Radicals (O2._, .OH, BPD-MA._) and Singlet Oxygen (1O2) generated by Irradiation of Benzoporphyrin derivative Monoacid Ring A”, Photochem. Photobiol., 65(5), pp 818-827, 1997.
R. Bays, G. Wagnières, D. Robert, J.-F. Theumann, A. Vitkin, J.-F. Savary, Ph. Monnier and H. van den Bergh, “Three-Dimensional Optical Phantom and its Application in Photodynamic Therapy”, Lasers in Surgery and Medicine, 21(3), pp 227 – 234, 1997.
G. Wagnières, A. Studzinsky, D. Braichotte, Ph. Monnier, Ch. Depeursinge, A. Châtelain and H. van den Bergh, “Clinical imaging fluorescence apparatus for the endoscopic photodetection of early cancers by use of Photofrin II”, Applied Optics, 36(22), pp 5608-5620, 1997.
J.-F. Savary, Ph. Monnier, Ch. Fontolliet, J. Mizeret, G. Wagnières, D. Braichotte and H. van den Bergh, “Photodynamic therapy for early squamous cell carcinomas of the eosophagus, bronchi and mouth with m-Tetra(Hydroxyphenyl) Chlorin”, Archives of Otolaryngol. Heard Neck Surg., 123, pp 162-168, 1997.
R. Bays, G. Wagnières, D. Robert, D. Braichotte, J.-F. Savary, Ph. Monnier and H. van den Bergh, “Light dosimetry for photodynamic therapy in the Esophagus”, Lasers in Surgery and Medicine, 20(3), pp 290-303, 1997.
P. Jichlinski, M. Forrer, J. Mizeret, Th. Glanzmann, D. Braichotte, G. Wagnières, G. Zimmer, L. Guilloud, F. Schmidlin, P. Graber, H. van den Bergh and H.-J. Leisinger, “Clinical evaluation of a method for detecting superficial transitional cell carcinoma of the bladder by light induced fluorescence of Protoporphyrin IX following topical application of 5-aminolevulinic acid: Preliminary results”, Lasers in Surgery and Medicine, 20(4), pp 402-408, 1997.
1996
J. Inderfurth and G. Wagnières, “Photoinduction of Fluorophores in the Retina using a 514 nm Argon Ion Laser”, German Journal of Ophthalmology, 5(6), pp 461-465, 1996.
F. Schmidlin, P. Jichlinski, G. Delacrétaz, G. Wagnières, H.-J. Leisinger et P. Graber, “Les indications et performances du laser en urologie”, Médecine et Hygiène, 54, pp 2208 – 2213, 1996.
P. Grosjean, J.-F. Savary, J. Mizeret, G. Wagnières, A. Woodtli, J.-F. Theumann, Ch. Fontolliet, H. van den Bergh and Ph. Monnier, “Photodynamic Therapy for Cancer of the Upper Aerodigestive Tract Using Tetra(m-hydroxyphenyl)chlorin”, J. Clin. Laser Medicine & Surgery, 14(5), pp 281-287, 1996.
D. Braichotte, J.-F. Savary, Th. Glanzmann, Ph. Monnier, G. Wagnières and H. van den Bergh, “Optimizing light dosimetry in photodynamic therapy of the bronchi by fluorescence spectroscopy”, Lasers in Medical Science, 11(4), pp 247-254, 1996.
P. Grosjean, J.-F. Savary, G. Wagnières, J. Mizeret, A. Woodtli, J.-F. Theumann, Ch. Fontolliet, H. van den Bergh and Ph. Monnier, “Tetra(m-hydroxyphenyl)chlorin clinical photodynamic therapy of early bronchial and esophageal cancers”, Lasers in Medical Science, 11(4), pp 227-235, 1996.
S. Andrejevic Blant, A. Woodtli, G. Wagnières, Ch. Fontolliet, H. van den Bergh and Ph. Monnier, “In vivo Fluence Rate Effects in Photodynamic Therapy of Early Cancers with Tetra(m-hydroxyphenyl)chlorin”, Photochemistry and Photobiology, 64(6), pp 963-968, 1996.
S. Andrejevic, J.-F. Savary, Ph. Monnier, Ch. Fontolliet, D. Braichotte, G. Wagnières and H. van den Bergh, “Measurement by fluorescence microscopy of the time-dependent distribution of meso-tetra-hydroxyphenylchlorin in healthy tissues and chemically-induced “early” squamous cell carcinoma of the Syrian Hamster cheek pouch”, Journal of Photochem. Photobiol. B: Biol., 36, pp 143-151, 1996.
R. Bays, G. Wagnières, D. Robert, D. Braichotte and H. van den Bergh, “Clinical determination of tissue optical properties by endoscopic spatially resolved reflectometry”, Applied Optics, 35 (10), pp 1756-1766, 1996.
1995
D. Braichotte, J. – F. Savary, P. Westermann, T. Glanzmann, S. Folli, G. Wagnières, Ph. Monnier and H. van den Bergh, “Clinical pharmacokinetic studies of tetra(meta-hydroxyphenyl)chlorin in squamous cell carcinoma by fluorescence spectroscopy at two wavelengths”, Int. Jour. Cancer, 63, pp 198 – 204, 1995.
D. Braichotte, G. Wagnières, R. Bays, Ph. Monnier and H. van den Bergh, “Clinical pharmacokinetic studies of Photofrin by fluorescence spectroscopy in the oral cavity, the esophagus and the bronchi”, Cancer, 75(11), pp 2768-2778, 1995.
1994
S. Folli, P. Westermann, D. Braichotte, G. Wagnières, A. Pèlegrin, G. Wagnières and H. van den Bergh, “Antibody-Indocyanin Conjugates for Immunophotodetection of Human Squamous Cell Carcinoma in Nude Mice”, Cancer Res., 54, pp 2643-2649, 1994.
1992
G. Wagnières, “Photochimiothérapie et photodétection du cancer à l’aide de photosensibilisateurs ou de colorants fluorescents”, Thèse EPFL No 1024, 1992.
A. Pèlegrin, S. Folli, G. Wagnières, D. Braichotte, F. Buchegger, A. Châtelain, H. van den Bergh and J.-P. Mach, “Photoimmunodiagnosis with antibody-fluorescein conjugates: in vitro and in vivo preclinical studies”, J. Cell. Pharmacol., 3(1), pp 141-145, 1992.
S. Folli, G. Wagnières, A. Pèlegrin, J.-M. Calmes, D. Braichotte, F. Buchegger, Y. Chalandon, J.-C. Givel, N. Hardman, Ch. Heusser, G. Chapuis, A. Châtelain, H. van den Bergh and J.-P. Mach, “Immunophotodiagnosis of colon carcinomas in patients injected with fluoresceinated chimeric antibodies against carcinoembryonic antigen”, Proc. Natl. Acad. Sci., 89, pp 7973-7977, 1992.
1991
A. Pèlegrin, S. Folli, F. Buchegger, J.-P. Mach, G. Wagnières and H. van den Bergh, “Antibody-fluorescein conjugates for photoimmunodiagnosis of human colon carcinoma in nude mice”, Cancer, 67 (10), pp 2529-2537, 1991.
1990
Ph. Monnier, M. Savary, Ch. Fontolliet, G. Wagnières, A. Châtelain, P. Cornaz, Ch. Depeursinge and H. van den Bergh, “Photodetection and photodynamic therapy of “early” squamous cell carcinomas of the pharynx, oesophagus and tracheo-bronchial tree”, Lasers in Medical Science, 5, pp 149-169, 1990.