Publications

2025

Journal Articles

Compensating nonlinearities in high-speed atomic force microscopy using data-driven feedforward controller design

N. Asmari; V. Cencen; M. Kangül; S. H. Andany; C. Tekin et al. 

Journal of Micro and Bio Robotics. 2025. Vol. 21, num. 2, p. 15. DOI : 10.1007/s12213-025-00194-3.

Hierarchy of Hydrophobic and Electrostatic Interactions in DNA–Membrane Phase Selectivity

S. H. Wong; Y-M. Lou; Y. Chen; D. Morzy; M. M. C. Bastings 

ACS Applied Materials & Interfaces. 2025. DOI : 10.1021/acsami.5c13271.

Pattern and Precision: Dna-based Mapping of Spatial Rules for T Cell Activation

S. Li; K. Paloja; M. M. C. Bastings 

NANOSCALE HORIZONS. 2025. DOI : 10.1039/d5nh00412h.

Stimuli-Responsive Oligolysine-PEG Coatings for Reductive-Triggered Decomplexation

H. J. Rodríguez-Franco; A. Kononenko; M. M. C. Bastings 

ACS Polymers Au. 2025. DOI : 10.1021/acspolymersau.5c00012.

Spatial and stoichiometric in situ analysis of biomolecular oligomerization at single-protein resolution

L. A. Masullo; R. Kowalewski; M. Honsa; L. Heinze; S. Xu et al. 

Nature Communications. 2025. Vol. 16. DOI : 10.1038/s41467-025-59500-z.

Evolution of multivalent supramolecular assemblies of aptamers with target-defined spatial organization

A. Kononenko; V. Caroprese; Y. Duhoo; C. Tekin; M. M. Bastings 

Nature Nanotechnology. 2025. DOI : 10.1038/s41565-025-01939-8.

Multivalent Presentation of TCRs on DNA Nanostructures as a Sensitive Probe for pMHC Detection

K. Paloja; H. J. Rodríguez-Franco; R. Jungmann; I. A. Parish; M. M. Bastings 

ACS Applied Nano Materials. 2025. num. 24, p. 12490 – 12497. DOI : 10.1021/acsanm.5c01296.

Interface flexibility controls the nucleation and growth of supramolecular networks

V. Caroprese; C. Tekin; V. Cencen; M. Mosayebi; N. Asmari et al. 

Nature chemistry. 2025. DOI : 10.1038/s41557-025-01741-y.

Reviews

Multivalent engineering of bio interfaces with DNA-based nanomaterials

S. Li; Y. Lou; M. M. Bastings 

Advanced Drug Delivery Reviews. 2025. Vol. 225, p. 115681. DOI : 10.1016/j.addr.2025.115681.

Theses

Programmable supramolecular nanoarchitectures for targeting biological patterns

A. Kononenko / M. M. C. Bastings (Dir.)  

Lausanne, EPFL, 2025. 

Mapping the Operative Space for Polymer-Biostabilized DNA Origami

H. J. Rodríguez Franco / M. M. C. Bastings (Dir.)  

Lausanne, EPFL, 2025. 

Electrostatic and Hydrophobic Mediation in DNA/Lipid Interactions: Toward the Design of Tailored DNA/Membrane Interfaces

S. H. Wong / M. M. C. Bastings (Dir.)  

Lausanne, EPFL, 2025. 

Patents

Method for multivalent selection of nucleic-acid-based binders using multimerization scaffold with target-tailored geometry

M. Bastings; A. Kononenko 

WO2025186451.

2025.

Method to impose a geometric arrangement to binding partners present on a biological interface

M. Bastings; K. Paloja 

WO2025125524.

2025.

2024

Journal Articles

Dynamic Surface Interactions Enable the Self-Assembly of Perfect Supramolecular Crystals

C. Tekin; V. Caroprese; M. M. Bastings 

ACS applied materials & interfaces. 2024. Vol. 16, num. 43, p. 59040 – 59048. DOI : 10.1021/acsami.4c11813.

Modulating the DNA/Lipid Interface through Multivalent Hydrophobicity

S. H. Wong; S. N. Kopf; V. Caroprese; Y. Zosso; D. Morzy et al. 

NANO LETTERS. 2024. Vol. 24, num. 36, p. 11210 – 11216. DOI : 10.1021/acs.nanolett.4c02564.

Unfolding a death signal to treat rheumatoid arthritis

M. E. Peter; M. M. C. Bastings 

NATURE MATERIALS. 2024. Vol. 23, num. 7, p. 882 – 883. DOI : 10.1038/s41563-024-01936-7.

The CD8+ T cell tolerance checkpoint triggers a distinct differentiation state defined by protein translation defects

W. Van Der Byl; S. Nüssing; T. J. Peters; A. Ahn; H. Li et al. 

Immunity. 2024. Vol. 57, num. 6, p. 1324 – 1344.e8. DOI : 10.1016/j.immuni.2024.04.026.

High-Speed Atomic Force Microscopy Imaging of DNA Three-Point-Star Motif Self Assembly Using Photothermal Off-Resonance Tapping

V. Cencen; B. Ghadiani; S. H. Andany; M. Kangul; C. Tekin et al. 

Jove-Journal Of Visualized Experiments. 2024. num. 205, p. e66470. DOI : 10.3791/66470.

Tailoring DNA Origami Protection: A Study of Oligolysine-PEG Coatings for Improved Colloidal, Structural, and Functional Integrity

H. J. Rodríguez-Franco; P. B. Hendrickx; M. M. Bastings 

ACS Polymers Au. 2024. DOI : 10.1021/acspolymersau.4c00085.

Theses

Coarse grain modelling of DNA self-assembly over multiple scales

V. Caroprese / M. Bastings (Dir.)  

Lausanne, EPFL, 2024. 

Exploring the self-assembly of supramolecular crystals with DNA tiles

C. Tekin / M. Bastings (Dir.)  

Lausanne, EPFL, 2024. 

2023

Journal Articles

Stabilizing Polymer Coatings Alter the Protein Corona of DNA Origami and Can Be Engineered to Bias the Cellular Uptake

H. J. Rodriguez-Franco; J. Weiden; M. M. C. Bastings 

Acs Polymers Au. 2023. DOI : 10.1021/acspolymersau.3c00009.

Biotechnological Frontiers of DNA Nanomaterials Continue to Expand: Bacterial Infection using Virus-Inspired Capsids

M. M. C. Bastings 

Angewandte Chemie International Edition. 2023. Vol. 62, num. 11, p. e202218334. DOI : 10.1002/anie.202218334.

Interplay of the mechanical and structural properties of DNA nanostructures determines their electrostatic interactions with lipid membranes

D. Morzy; C. Tekin; V. Caroprese; R. Rubio-Sanchez; L. Di Michele et al. 

Nanoscale. 2023. DOI : 10.1039/d2nr05368c.

Theses

Exploring the interplay of molecular pattern and valency for selective interactions at the bio-interface

K. Paloja / M. M. C. Bastings (Dir.)  

Lausanne, EPFL, 2023. 

2022

Journal Articles

Multivalent Pattern Recognition through Control of Nano-Spacing in Low-Valency Super-Selective Materials

H. Bila; K. Paloja; V. Caroprese; A. Kononenko; M. M. C. Bastings 

Journal Of The American Chemical Society. 2022. DOI : 10.1021/jacs.2c08529.

Selective Integrin alpha(5)beta(1) Targeting through Spatially Constrained Multivalent DNA-Based Nanoparticles

E. E. Kurisinkal; V. Caroprese; M. M. Koga; D. Morzy; M. M. C. Bastings 

Molecules. 2022. Vol. 27, num. 15, p. 4968. DOI : 10.3390/molecules27154968.

Strategic Insights into Engineering Parameters Affecting Cell Type-Specific Uptake of DNA-Based Nanomaterials

M. M. Koga; A. Comberlato; H. J. Rodriguez-Franco; M. M. C. Bastings 

Biomacromolecules. 2022. Vol. 23, num. 6, p. 2586 – 2594. DOI : 10.1021/acs.biomac.2c00282.

Spatially Controlled Activation of Toll-like Receptor 9 with DNA-Based Nanomaterials

A. Comberlato; M. M. Koga; S. Nuessing; I. A. Parish; M. M. C. Bastings 

Nano Letters. 2022. Vol. 22, num. 6, p. 2506 – 2513. DOI : 10.1021/acs.nanolett.2c00275.

Reviews

Significance of Receptor Mobility in Multivalent Binding on Lipid Membranes

D. Morzy; M. Bastings 

Angewandte Chemie International Edition. 2022. Vol. 61, num. 13, p. e202114167. DOI : 10.1002/anie.202114167.

Theses

Selective integrin targeting with DNA-based nanomaterials

E. E. Kurisinkal / M. M. C. Bastings (Dir.)  

Lausanne, EPFL, 2022. 

DNA-based biomaterials for nanoscale controlled modulation of immune cells

A. Comberlato / M. M. C. Bastings (Dir.)  

Lausanne, EPFL, 2022. 

Multivalent Pattern Recognition Through Engineering of Spatial Tolerance in DNA-Based Nanomaterials

H. Bila / M. M. C. Bastings (Dir.)  

Lausanne, EPFL, 2022. 

2021

Journal Articles

Quantification of Strand Accessibility in Biostable DNA Origami with Single-Staple Resolution

A. S. Eklund; A. Comberlato; I. A. Parish; R. Jungmann; M. M. C. Bastings 

Acs Nano. 2021. Vol. 15, num. 11, p. 17668 – 17677. DOI : 10.1021/acsnano.1c05540.

Conference Papers

Probing the importance of valency and spatial organization of immune regulator PD-1 with DNA-based nanomaterials

J. Weiden; K. Paloja; A. Comberlato; C. Tekin; M. M. C. Bastings 

2021.  p. 120 – 120.

Reviews

DNA origami nanostructures for controlled therapeutic drug delivery

J. Weiden; M. Bastings 

Current Opinion in Colloid & Interface Science. 2021. Vol. 52, p. 101411. DOI : 10.1016/j.cocis.2020.101411.

2020

Journal Articles

Endothelial extracellular vesicles contain protective proteins and rescue ischemia-reperfusion injury in a human heart-on-chip

M. Yadid; J. U. Lind; H. A. M. Ardona; S. P. Sheehy; L. E. Dickinson et al. 

Science Translational Medicine. 2020. Vol. 12, num. 565, p. eaax8005. DOI : 10.1126/scitranslmed.aax8005.

2019

Journal Articles

Quantifying Guest-Host Dynamics in Supramolecular Assemblies to Analyze Their Robustness

M. M. C. Bastings; T. M. Hermans; A. J. H. Spiering; E. W. L. Kemps; L. Albertazzi et al. 

Macromolecular Bioscience. 2019. Vol. 19, num. 1, p. 1800296. DOI : 10.1002/mabi.201800296.

Large‐Range HS‐AFM Imaging of DNA Self‐Assembly through In Situ Data‐Driven Control

A. P. Nievergelt; C. M. Kammer; C. Brillard; E. E. Kurisinkal; M. Bastings et al. 

Small Methods. 2019. Vol. 3, p. 1900031. DOI : 10.1002/smtd.201900031.

Reviews

Nucleic acids presenting polymer nanomaterials as vaccine adjuvants

A. Comberlato; K. Paloja; M. M. C. Bastings 

Journal of Materials Chemistry B. 2019. Vol. 7, num. 41, p. 6321 – 6346. DOI : 10.1039/c9tb01222b.

Engineering a stable future for DNA-origami as a biomaterial

H. Bila; E. E. Kurisinkal; M. M. C. Bastings 

Biomaterials Science. 2019. Vol. 7, num. 2, p. 532 – 541. DOI : 10.1039/c8bm01249k.

2016

Journal Articles

Adjuvant-Loaded Subcellular Vesicles Derived From Disrupted Cancer Cells for Cancer Vaccination

A. S. Cheung; S. T. Koshy; A. G. Stafford; M. M. C. Bastings; D. J. Mooney 

Small. 2016. Vol. 12, num. 17, p. 2321 – 2333. DOI : 10.1002/smll.201600061.

Reviews

Supramolecular Polymers in Aqueous Media

E. Krieg; M. M. C. Bastings; P. Besenius; B. Rybtchinski 

Chemical Reviews. 2016. Vol. 116, num. 4, p. 2414 – 2477. DOI : 10.1021/acs.chemrev.5b00369.

2015

Journal Articles

An Injectable and Drug-loaded Supramolecular Hydrogel for Local Catheter Injection into the Pig Heart

A. C. H. Pape; M. H. Bakker; C. C. S. Tseng; M. Bastings; S. Koudstaal et al. 

Journal of Visualized Experiments. 2015. num. 100, p. e52450. DOI : 10.3791/52450.

2014

Journal Articles

Sustained Delivery of Insulin-Like Growth Factor-1/Hepatocyte Growth Factor Stimulates Endogenous Cardiac Repair in the Chronic Infarcted Pig Heart

S. Koudstaal; M. Bastings; D. A. M. Feyen; C. D. Waring; F. J. Van Slochteren et al. 

Journal of Cardiovascular Translational Research. 2014. Vol. 7, num. 2, p. 232 – 241. DOI : 10.1007/s12265-013-9518-4.

Mesoscale Characterization of Supramolecular Transient Networks Using SAXS and Rheology

A. Pape; M. Bastings; R. Kieltyka; H. Wyss; I. Voets et al. 

International Journal of Molecular Sciences. 2014. Vol. 15, num. 1, p. 1096 – 1111. DOI : 10.3390/ijms15011096.

2013

Journal Articles

Mesoscale Modulation of Supramolecular Ureidopyrimidinone-Based Poly(ethylene glycol) Transient Networks in Water

R. E. Kieltyka; A. C. H. Pape; L. Albertazzi; Y. Nakano; M. Bastings et al. 

Journal of the American Chemical Society. 2013. Vol. 135, num. 30, p. 11159 – 11164. DOI : 10.1021/ja403745w.

A Fast pH-Switchable and Self-Healing Supramolecular Hydrogel Carrier for Guided, Local Catheter Injection in the Infarcted Myocardium

M. Bastings; S. Koudstaal; R. E. Kieltyka; Y. Nakano; A. C. H. Pape et al. 

Advanced Healthcare Materials. 2013. Vol. 3, num. 1, p. 70 – 78. DOI : 10.1002/adhm.201300076.

Conference Papers

Sustained Delivery Of Insulin-Like Growth Factor-1/Hepatocyte Growth Factor Promotes Endogenous Cardiac Repair And Regeneration In The Chronic Ischemic Heart

S. Koudstaal; M. Bastings; G. Ellison; D. Feyen; C. Waring et al. 

2013. 62nd Annual Scientific Session of the American College of Cardiology, San Francisco, CA, March 9-11, 2013. DOI : 10.1016/S0735-1097(13)61141-9.

Sustained delivery of insulin-like growth factor-1/hepatocyte growth factor promotes endogenous cardiac repair and regeneration in the chronic ischemic heart

S. Koudstaal; M. Bastings; D. A. M. Feyen; C. D. Waring; D. Torella et al. 

2013. Congress of the European Society of Cardiology (ESC), Amstersam, Netherlands, August 31 – September 04, 2013. DOI : 10.1093/eurheartj/eht308.P1450.

2012

Journal Articles

Modular synthesis of supramolecular ureidopyrimidinone–peptide conjugates using an oxime ligation strategy

R. E. Kieltyka; M. Bastings; G. C. Van Almen; P. Besenius; E. W. L. Kemps et al. 

Chemical Communications (ChemComm). 2012. Vol. 48, num. 10, p. 1452 – 1454. DOI : 10.1039/C1CC14728E.

Hierarchical Formation of Supramolecular Transient Networks in Water: A Modular Injectable Delivery System

P. Y. W. Dankers; T. M. Hermans; T. W. Baughman; Y. Kamikawa; R. E. Kieltyka et al. 

Advanced Materials. 2012. Vol. 24, num. 20, p. 2703 – 2709. DOI : 10.1002/adma.201104072.

2011

Journal Articles

From Phage Display to Dendrimer Display: Insights into Multivalent Binding

M. M. C. Bastings; B. A. Helms; I. Van Baal; T. M. Hackeng; M. Merkx et al. 

Journal of the American Chemical Society. 2011. Vol. 133, num. 17, p. 6636 – 6641. DOI : 10.1021/ja110700x.

2010

Journal Articles

Macrocyclization of enzyme-based supramolecular polymers

M. Bastings; T. F. A. De Greef; J. L. J. Van Dongen; M. Merkx; E. W. Meijer 

Chemical Science. 2010. Vol. 1, num. 1, p. 79. DOI : 10.1039/c0sc00108b.

2008

Journal Articles

One-step refolding and purification of disulfide-containing proteins with a C-terminal MESNA thioester

M. Bastings; I. Van Baal; E. Meijer; M. Merkx 

BMC Biotechnology. 2008. Vol. 8, num. 1, p. 76. DOI : 10.1186/1472-6750-8-76.