Mastering preclinical proton and deuterium-based fast MRSI in the brain: from setup to execution

G. Nossa; E. Mougel; B. Alves; T. T. Phan; A. Siviglia et al. 

MRS4Brain: a software for preclinical proton and deuterium-based MR spectroscopic imaging data

B. Alves; T. T. Phan; G. Briand; A. Siviglia; G. Nossa et al. 

Development of enhanced and accelerated 2D and 3D 1H-MRSI at ultra-high field for mapping rodent brain metabolism

MRS4Brain: a processing toolbox for preclinical MR spectroscopy and spectroscopic imaging data

B. Alves; T. Phan; G. Briand; A. Siviglia; G. Nossa et al. 

Towards harmonized spectral quantification in MRSI: Comparative analysis of Backward-Linear-Predicted and original ¹H-FID-MRSI dephased data

A. Siviglia; B. Alves; C. Cudalbu; B. Lanz 

Metabolic modelling and time-resolved mapping of glucose oxidative metabolism in rats brain by indirect deuterium detection with ¹ H-FID-MRSI at 9.4T

A. Siviglia; G. Nossa; B. Alves; F. Niess; A. Duguid et al. 

Comparison of Low‐Rank Denoising Methods for Dynamic Deuterium MRSI at 7 T

A. Duguid; F. Niess; W. Bogner; L. Hingerl; V. Bader et al. 

Heterozygous females from a rat model for creatine transporter deficiency reveal altered behavioral response to stressors, normal body weight and slight metabolic changes

L. Duran-Trio; M. Lanzillo; D. Simicic; C. Roux-Petronelli; S. J. Bruce et al. 

Fast High-Resolution Metabolite Mapping in the rat Brain Using ¹H-FID-MRSI at 14.1 T

D. Simicic; B. Alves; J. Mosso; R. B. van Heeswijk; G. Briand et al. 

Noise-reduction techniques for 1H-FID-MRSI at 14.1 T: Monte Carlo validation and in vivo application

B. Alves; D. Simicic; J. Mosso; T. P. Lê; G. M. A. Briand et al. 

Rescue of myocytes and locomotion through AAV2/9-2YF intracisternal gene therapy in a rat model of creatine transporter deficiency

G. Fernandes-Pires; M. D. Azevedo; M. Lanzillo; C. Roux-Petronelli; P-A. Binz et al. 

Diffusion of brain metabolites highlights altered brain microstructure in type C hepatic encephalopathy: a 9.4 T preliminary study

J. Mosso; G. Briand; K. Pierzchala; D. Simicic; A. Sierra et al. 

Inhibition of urease-mediated ammonia production by 2-octynohydroxamic acid in hepatic encephalopathy

D. Evstafeva; F. Ilievski; Y. Bao; Z. Luo; B. Abramovic et al. 

Diffusion-weighted MR spectroscopy: Consensus, recommendations, and resources from acquisition to modeling

C. Ligneul; C. Najac; A. Doring; C. Beaulieu; F. Branzoli et al. 

Diffusion-weighted SPECIAL improves the detection of J-coupled metabolites at ultrahigh magnetic field

J. Mosso; D. Simicic; B. Lanz; R. Gruetter; C. Cudalbu 

Editorial for the special issue on Brain Biochemistry in Liver Disease

C. Cudalbu; A. J. L. Cooper 

Age Dependence of Neurometabolic Changes in a Rat Pup Model of Type C Hepatic Encephalopathy

D. Simicic; V. Rackayova; O. Braissant; C. Toso; G. Oldani et al. 

New Insights Into Brain Energy Metabolism in Type C Hepatic Encephalopathy: A Dual ¹⁸F-FDG PET and 9.4T ¹H MRS Preclinical Study

J. Mosso; T. Yin; C. Poitry-Yamate; D. Simicic; M. Lepore et al. 

Evaluation of a Hydroxamate-Based Urease Inhibitor in a Rodent Model of Hepatic Encephalopathy

D. Evstafeva; F. Ilievski; Y. Bao; Z. Luo; B. Abramovic et al. 

The Beneficial Effect of Oral Cr Supplementation in an Early Childhood Rat Model of Chronic Hepatic Encephalopathy: In Vivo Longitudinal ¹H and ³¹P Magnetic Resonance Spectroscopy Study

D. Simicic; O. Braissant; K. Pierzchala; S. Mitrea; D. Sessa et al. 

Brain Regional Differences in the Developing Brain Using an Animal Model of Type C Hepatic Encephalopathy

D. Simicic; K. Pierzchala; O. Braissant; C. Toso; G. Oldani et al. 

Lessons on brain edema in HE: from cellular to animal models and clinical studies

K. Pierzchala; A. Hadjihambi; J. Mosso; R. Jalan; C. F. F. Rose et al. 

Automated segmentation and labeling of subcutaneous mouse implants at 14.1T

J. Adda; G. Bioley; D. van de Ville; C. Cudalbu; M. G. Preti et al. 

High field brain proton magnetic resonance spectroscopy and volumetry in children with chronic, compensated liver disease-A pilot study

C. Cudalbu; L. Xin; B. Marechal; S. Lachat; F. Zangas-Gheri et al. 

Neurometabolic changes in a rat pup model of type C hepatic encephalopathy depend on age at liver disease onset

D. Simicic; V. Rackayova; O. Braissant; C. Toso; G. Oldani et al. 

Central Nervous System Oxidative Stress interplay with inflammation in a rat model of Type C Hepatic Encephalopathy – brothers in arms?

K. Pierzchala; D. Simicic; A. Sienkiewicz; D. Sessa; S. Mitrea et al. 

Harmonization of multi-scanner in vivo magnetic resonance spectroscopy: ENIGMA consortium task group considerations

A. D. Harris; H. Amiri; M. Bento; R. Cohen; C. R. K. Ching et al. 

Neurometabolic profiles of bile duct ligated rats after the treatment with an urease inhibitor – 1H MRS dataset

D. Evstafeva; J-C. Leroux; C. R. Cudalbu; D. Simicic 

New insights into rodent brain microstructure and metabolism in hepatic encephalopathy

MP-PCA denoising for diffusion MRS data: promises and pitfalls

J. Mosso; D. Simicic; K. Simsek; R. Kreis; C. Cudalbu et al. 

Overview of oxidative stress findings in hepatic encephalopathy: From cellular and ammonium-based animal models to human data

D. Simicic; C. Cudalbu; K. Pierzchala 

Central Nervous System Oxidative Stress Interplay With Inflammation In A Rat Model Of Type C Hepatic Encephalopathy – Brothers In Arms?

P. Katarzyna; S. Dunja; S. Dario; M. Stefanita; B. Olivier et al. 

Abnormal brain oxygen homeostasis in an animal model of liver disease

A. Hadjihambi; C. Cudalbu; K. Pierzchala; D. Simicic; C. Donnelly et al. 

PET CMRglc mapping and H-1-MRS show altered glucose uptake and neurometabolic profiles in BDL rats

J. Mosso; T. Yin; C. Poitry-Yamate; D. Simicic; M. Lepore et al. 

Quantitative FDG-PET and 1H-MRS reveal altered glucose uptake and neurometabolic profiles in BDL rats

J. Mosso; T. Yin; C. Poitry-Yamate; D. Simicic; M. Lepore et al. 

Central nervous system and systemic oxidative stress interplay with inflammation in a bile duct ligation rat model of type C hepatic encephalopathy (vol 178, pg 295, 2022)

K. Pierzchala; D. Simicic; A. Sienkiewicz; D. Sessa; S. Mitrea et al. 

Advanced metabolite mapping at ultra-high field using 1H-MRS, 1H-MRSI and macromolecules: applications in a rat model of type C hepatic encephalopathy

Creatine transporter-deficient rat model shows motor dysfunction, cerebellar alterations, and muscle creatine deficiency without muscle atrophy

L. Duran-Trio; G. Fernandes-Pires; J. Grosse; I. Soro-Arnaiz; C. Roux-Petronelli et al. 

Central nervous system and systemic oxidative stress interplay with inflammation in a bile duct ligation rat model of type C hepatic encephalopathy

K. Pierzchala; D. Simicic; A. Sienkiewicz; D. Sessa; S. Mitrea et al. 

A Standardized Brain Molecular Atlas: A Resource for Systems Modeling and Simulation

P. Shichkova; J. S. Coggan; H. Markram; D. Keller 

Probiotics combined with rifaximin influence the neurometabolic changes in a rat model of type C HE

E. Flatt; V. A. McLin; O. Braissant; K. Pierzchala; P. Mastromarino et al. 

Metabolic and transcriptomic profiles of glioblastoma invasion revealed by comparisons between patients and corresponding orthotopic xenografts in mice

C. Cudalbu; P. Bady; M. Lai; L. Xin; O. Gusyatiner et al. 

In vivo macromolecule signals in rat brain 1 H‐MR spectra at 9.4T: Parametrization, spline baseline estimation, and T 2 relaxation times

D. Simicic; V. Rackayová; L. Xin; I. Tkáč; T. Borbath et al. 

The first knock-in rat model for glutaric aciduria type I allows further insights into pathophysiology in brain and periphery

M. G. Melo; N. Remacle; H-P. Cudre-Cung; C. Roux; M. Poms et al. 

2021 ISHEN guidelines on animal models of hepatic encephalopathy

S. DeMorrow; C. Cudalbu; N. Davies; A. R. Jayakumar; C. F. Rose 

Hyperpolarized C-13-glucose magnetic resonance highlights reduced aerobic glycolysis in vivo in infiltrative glioblastoma

M. Mishkovsky; O. Gusyatiner; B. Lanz; C. Cudalbu; I. Vassallo et al. 

Minimum Reporting Standards for in vivo Magnetic Resonance Spectroscopy (MRSinMRS): Experts’ consensus recommendations

A. Lin; O. Andronesi; W. Bogner; I-Y. Choi; E. Coello et al. 

Probiotics improve the neurometabolic profile of rats with chronic cholestatic liver disease

V. Rackayova; E. Flatt; O. Braissant; J. Grosse; D. Capobianco et al. 

Late post‐natal neurometabolic development in healthy male rats using 1 H and 31 P Magnetic Resonance Spectroscopy

V. Račkayová; D. Simicic; G. Donati; O. Braissant; R. Gruetter et al. 

A new rat model of creatine transporter deficiency reveals behavioral disorder and altered brain metabolism

L. Duran-Trio; G. Fernandes-Pires; D. Simicic; J. Grosse; C. Roux-Petronelli et al. 

Contribution of macromolecules to brain H-1 MR spectra: Experts’ consensus recommendations

C. Cudalbu; K. L. Behar; P. K. Bhattacharyya; W. Bogner; T. Borbath et al. 

Magnetic resonance spectroscopy in the rodent brain: Experts’ consensus recommendations

B. Lanz; A. Abaei; O. Braissant; I-Y. Choi; C. Cudalbu et al. 

Terminology and concepts for the characterization of in vivo MR spectroscopy methods and MR spectra: Background and experts’ consensus recommendations

R. Kreis; V. Boer; I-Y. Choi; C. Cudalbu; R. A. de Graaf et al. 

B(0)shimming for in vivo magnetic resonance spectroscopy: Experts’ consensus recommendations

C. Juchem; C. Cudalbu; R. A. de Graaf; R. Gruetter; A. Henning et al. 

MP-PCA denoising dramatically improves SNR in large-sized MRS data: an illustration in diffusion-weighted MRS

I. Jelescu; J. Veraart; C. R. Cudalbu 

Longitudinal osmotic and neurometabolic changes in young rats with chronic cholestatic liver disease

V. Rackayova; O. Braissant; A-L. Rougemont; C. Cudalbu; V. A. McLin 

Reply to: “Magnetic resonance spectroscopy: A surrogate marker of hepatic encephalopathy?”

V. A. Mclin; O. Braissant; C. Cudalbu 

Bile Acids And Ammonium Contribute To Changes In Dendritic Spine Distribution In An Organotypic Culture Of Rat Hippocampus

L. Giovannoni; M. Deroo; O. Braissant; H. Henry; C. R. Cudalbu et al. 

Cholestasis Decreases Dendritic Spine Density in a Rat Hippocampal Organotypic Culture

L. Giovannoni; M. De Roo; O. Braissant; H. Henry; C. Cudalbu et al. 

Probiotics Combined With Rifaximin for the Treatment of Chronic Hepatic Encephalopathy: A Longitudinal In Vivo 1H-MRS Study of Brain Metabolism Using BDL Rats

E. Flatt; O. Braissant; S. Mitrea; D. Sessa; P. Mastromarino et al. 

Antibiotic Rifaximin for Treatment of Chronic Liver Disease-Induced HE: A Longitudinal In Vivo 1H-MRS Study of Brain Metabolism on BDL Rats

E. Flatt; O. Braissant; S. Mitrea; D. Sessa; R. Gruetter et al. 

Hippocampal and Cerebellar Astrocytes Morphological Alterations in a Rat Model of Chronic Hepatic Encephalopathy

K. Pierzchala; D. Simicic; O. Braissant; V. A. McLin; C. Cudalbu 

In Vivo Longitudinal 1H MRS Study of Hippocampal, Cereberal and Striatal Metabolic Changes in the Adult Brain Using an Animal Model of Chronic Hepatic Encephalopathy

D. Simicic; K. Pierzchala; V. Rackayova; O. Braissant; S-O. Mitrea et al. 

Longitudinal neurometabolic changes in the hippocampus of a rat model of chronic hepatic encephalopathy

O. Braissant; V. Rackayova; K. Pierzchala; J. Grosse; V. A. McLin et al. 

Brain Regional Susceptibility to Oxidative Stress in a Rat Model of Chronic Hepatic Encephalopathy: In-Vivo 1H MRS, Ex-Vivo ESR Spectroscopy and Histology Findings

K. Pierzchala; D. Simicic; V. Rackayova; D. Sessa; A. Sienkiewicz et al. 

Neurometabolism in Grey Matter of Children With Chronic Liver Disease or Portosystemic Shunting: A 1H-MRS Study at 7T

C. Cudalbu; L. Xin; S. Lachat; N. Valenza; F. Zangas-Gehri et al. 

Brain Edema in Chronic Hepatic Encephalopathy

C. Cudalbu; S. D. Taylor-Robinson 

Neurochemical Modifications in the Hippocampus, Cortex and Hypothalamus of Mice Exposed to Long-Term High-Fat Diet

B. Lizarbe; A. F. Soares; S. Larsson; J. M. N. Duarte 

Methodological consensus on clinical proton MRS of the brain: Review and recommendations

M. Wilson; O. Andronesi; P. B. Barker; R. Bartha; A. Bizzi et al. 

Metabolic And Transcriptional Profiles Of Gbm Invasion: Comparison Of Patients And Paired Patient Derived Xenografts Using1H Magnetic Resonance Spectroscopy And Imaging (7T And 14T) And Rna-Sequencing

M. Hegi; C. Cudalbu; P. Bady; M. Lai; L. Xin et al. 

Brain metabolism during Chronic Hepatic Encephalopathy studied by in vivo 1H and 31P MRS

In vivo (13)C MRS in the mouse brain at 14.1 Tesla and metabolic flux quantification under infusion of [1,6-(13)C2]glucose

M. Lai; B. Lanz; C. Poitry-Yamate; J. F. Romero; C. M. Berset et al. 

Probing perturbed hepatic metabolism in bile-duct-ligated rats with hyperpolarized 13C pyruvate and arginine

H. A. I. Yoshihara; D. Firsov; C. R. Cudalbu; R. Gruetter 

In vivo characterization of brain metabolism by 1 H MRS, 13 C MRS and 18 FDG PET reveals significant glucose oxidation of invasively growing glioma cells

M. Lai; I. Vassallo; B. Lanz; C. Poitry-Yamate; M-F. Hamou et al. 

Creatine in the central nervous system: From magnetic resonance spectroscopy to creatine deficiencies

V. Rackayova; C. Cudalbu; P. J. W. Pouwels; O. Braissant 

Social isolation stress and chronic glutathione deficiency have a common effect on the glutamine-to-glutamate ratio and myo-inositol concentration in the mouse frontal cortex

A. Corcoba; R. Gruetter; K. Q. Do; J. M. N. Duarte 

Editorial for the special issue on introduction to in vivo Magnetic Resonance Spectroscopy (MRS): A method to non-invasively study metabolism

C. Cudalbu; A. J. L. Cooper 

Metabolic changes in developing brain due to chronic liver disease: an in vivo longitudinal and multiparametric study using P-31-MRS (magnetic resonance spectroscopy), P-31-Magnetization transfer and H-1-MRS

V. Rackayova; V. Mlynarik; C. Cudalbu 

MRS studies of neuroenergetics and glutamate/glutamine exchange in rats: Extensions to hyperammonemic models

B. Lanz; V. Rackayova; O. Braissant; C. Cudalbu 

(1)H and (31)P magnetic resonance spectroscopy in a rat model of chronic hepatic encephalopathy: in vivo longitudinal measurements of brain energy metabolism

V. Rackayova; O. Braissant; V. A. McLin; C. Berset; B. Lanz et al. 

Brain edema: a valid endpoint for measuring hepatic encephalopathy?

C. Bémeur; C. Cudalbu; G. Dam; A. S. Thrane; A. J. L. Cooper et al. 

Hyperpolarized 6Li as a probe for hemoglobin oxygenation level

R. Balzan; M. Mishkovsky; Y. Simonenko; R. B. van Heeswijk; R. Gruetter et al. 

In Vivo Longitudinal (1)H MRS Study of Transgenic Mouse Models of Prion Disease in the Hippocampus and Cerebellum at 14.1 T

C. Cudalbu; M. Craveiro; V. Mlynárik; J. Bremer; A. Aguzzi et al. 

Studying glioblastoma progression in a rat model of human glioma initiating cells using 1H MRS and DTI

M. Mishkovsky; C. R. Cudalbu; E. Can; D. Mario; I. Radovanovic et al. 

Neurochemical profile differentiation of glioma induced by cancer stem cells expressing WIF1: a 1H-MRS longitudinal study at 14.1T

M. Lai; C. R. Cudalbu; B. Lanz; I. Vassallo; M-F. Hamou et al. 

Clinical Proton MR Spectroscopy in Central Nervous System Disorders

G. Öz; J. R. Alger; P. B. Barker; R. Bartha; A. Bizzi et al. 

In vivo 13C MRS in the mouse brain at 14.1 T and metabolic flux quantification during infusion of [1,6-13C2] Glucose

M. Lai; B. Lanz; C. J. d. C. Romero; C. R. Cudalbu; R. Gruetter 

Is the macromolecule signal tissue-specific in healthy human brain? A 1H MRS study at 7 tesla in the occipital lobe

B. Schaller; L. Xin; R. Gruetter 

Cross polarization from H-1 to quadrupolar Li-6 nuclei for dissolution DNP

A. J. P. Linde; A. Bornet; J. Milani; B. Vuichoud; R. Melzi et al. 

Optimized MEGA-SPECIAL for in vivo glutamine detection in the rat brain at 14.1 T

M. Craveiro; C. Cudalbu; V. Mlynárik; R. Gruetter 

Hyperpolarization of Deuterated Metabolites via Remote Cross-Polarization and Dissolution Dynamic Nuclear Polarization

B. Vuichoud; J. Milani; A. Bornet; R. Melzi; S. Jannin et al. 

In vivo brain macromolecule signals in healthy and glioblastoma mouse models: 1H magnetic resonance spectroscopy, post-processing and metabolite quantification at 14.1 T

M. Craveiro; V. Clément-Schatlo; D. Marino; R. Gruetter; C. Cudalbu 

In vivo brain energy metabolism in a rat model of chronic Hepatic Encephalopathy using 31P MRS

C. Cudalbu; O. Braissant; A. Jayaswal; R. Gruetter; V. A. Mclin 

Brain metabolism in rat model of human glioma initiating cells

M. Mishkovsky; C. R. Cudalbu; A. Comment; D. Mario; I. Radovanovic et al. 

Proton T(1) relaxation times of metabolites in human occipital white and gray matter at 7 T

L. Xin; B. Schaller; V. Mlynarik; H. Lu; R. Gruetter 

Methods for Molecular Magnetic Resonance Imaging and Magnetic Resonance Spectroscopy using Hyperpolarized Nuclei

The C57BL/6 mouse exhibits sporadic congenital portosystemic shunts

C. Cudalbu; V. McLin; H. Lei; J. Duarte; A. Rougemont et al. 

Differences in CNS metabolism between pups and adults in an animal model of biliary cirrhosis: longitudinal, non-invasive in vivo study

C. Cudalbu; O. Braissant; V. A. Mclin 

Hepatic encephalopathy and brain metabolism: a longitudinal in vivo study

C. Cudalbu; V. McLin; O. Braissant 

Differences in CNS metabolism between pups and adults in an animal model of biliary cirrhosis: longitudinal, non-invasive in vivo study

C. Cudalbu; O. Braissant; V. A. Mclin 

In vivo brain energy metabolism in a rat model of chronic Hepatic Encephalopathy using 31P MRS

C. Cudalbu; O. Braissant; A. Jayaswal; R. Gruetter; V. A. McLin 

Quantification of the neurochemical profile using simulated macromolecule resonances at 3 T

B. Schaller; L. Xin; C. Cudalbu; R. Gruetter 

In vivo and longitudinal assessment of brain metabolism in Hepatic Encephalopathy using 1H MRS

C. R. Cudalbu; V. McLin; O. Braissant; R. Gruetter 

Single spin-echo T 2 relaxation times of cerebral metabolites at 14.1 T in the in vivo rat brain

L. Xin; G. Gambarota; C. Cudalbu; V. Mlynárik; R. Gruetter 

In vivo studies of brain metabolism in animal models of Hepatic Encephalopathy using (1)H Magnetic Resonance Spectroscopy

C. Cudalbu 

The C57BL/6 mouse exhibits sporadic congenital portosystemic shunts

C. R. Cudalbu; V. McLin; H. Lei; J. das Neves Duarte; A-L. Rougemont et al. 

Ammonia toxicity to the brain

O. Braissant; V. A. McLin; C. Cudalbu 

Which prior knowledge? Quantification of in vivo brain (13) C MR spectra following (13) C glucose infusion using AMARES

B. Lanz; J. M. N. Duarte; N. Kunz; V. Mlynárik; R. Gruetter et al. 

The C57BL/6J Mouse Exhibits Sporadic Congenital Portosystemic Shunts

C. Cudalbu; V. A. Mclin; H. Lei; J. M. N. Duarte; A-L. Rougemont et al. 

Proton and phosphorus magnetic resonance spectroscopy of a mouse model of Alzheimer’s disease

V. Mlynárik; M. Cacquevel; L. Sun-Reimer; S. Janssens; C. Cudalbu et al. 

In vivo metabolic profiling of glioma-initiating cells using proton magnetic resonance spectroscopy at 14.1 Tesla

V. Mlynarik; C. R. Cudalbu; V. Clement; D. Marino; I. Radovanovic et al. 

Cerebral glutamine metabolism under hyperammonemia determined in vivo by localized H-1 and N-15 NMR spectroscopy

C. R. Cudalbu; B. Lanz; J. M. N. Duarte; F. D. Morgenthaler; Y. Pilloud et al. 

The neurochemical profile quantified by in vivo(1)H NMR spectroscopy

J. M. N. Duarte; H. Lei; V. Mlynárik; R. Gruetter 

QUANTIFICATION DIFFERENCES OF 1H SPECTRA IN HUMAN BRAIN AT 3 TESLA USING THE ACQUIRED MACROMOLECULE BASELINE OR THE BUILT-IN LCMODEL SPLINE BASELINE

B. Schaller; X. Liu; R. Gruetter 

Assessment Of Cerebral Osmotic Regulation In A Rat Model Of Biliary Cirrhosis Using MR Spectroscopy

V. A. McLin; O. Braissant; Y. van de Looij; N. Kunz; R. Gruetter et al. 

Phosphorus MRS Study of a Murine Model of Peripheral Arterial Disease

V. Mlynárik; M. Pellegrin; C. R. Cudalbu; L. Mazzolai; R. Gruetter 

In vivo longitudinal 1H Spectroscopic Imaging and Diffusion Tensor Imaging studies at 9.4T in a rat model of chronic liver failure

C. R. Cudalbu; V. McLin; O. Braissant; N. Kunz; Y. Van de Looij et al. 

In vivo longitudinal 1H Spectroscopic Imaging and Diffusion Tensor Imaging studies at 9.4T in a rat model of chronic liver failure

C. R. Cudalbu; V. McLin; O. Braissant; N. Kunz; Y. van de Looij et al. 

Brain osmolytes and brain edema in a rat model of chronic liver failure: in vivo longitudinal 1H Spectroscopic imaging and Diffusion tensor imaging studies at 9.4T

C. R. Cudalbu; O. Braissant; M. Lepore; R. Gruetter; V. McLin 

Handling macromolecule signals in the quantification of the neurochemical profile

C. Cudalbu; V. Mlynárik; R. Gruetter 

Localized in vivo hyperpolarization transfer sequences

M. Mishkovsky; T. Cheng; A. Comment; R. Gruetter 

High-resolution mapping of the neurochemical profile after focal ischemia in mice

M. Alf; H. Lei; C. Berthet; L. Hirt; R. Gruetter et al. 

Imaging the in vivo effect of hyperammonemia in the rat brain: a Spectroscopic Imaging and Diffusion Tensor Imaging study

C. R. Cudalbu; N. Kunz; B. Lanz; Y. van de Looij; V. Mlynárik et al. 

In vivo longitudinal 1H MRS study of transgenic mouse models of prion disease in the hippocampus and cerebellum at 14.1T

C. R. Cudalbu; M. Craveiro; V. Mlynárik; J. Bremer; A. Aguzzi et al. 

In vivo localized 15N MRS detection of hyperpolarized 15N labeled choline in the rat brain

C. R. Cudalbu; A. Comment; T. Cheng; M. Mishkovsky; R. Gruetter 

In vivo metabolic profiling of glioma-initiating cells using proton magnetic resonance spectroscopy at 14.1 Tesla

V. Clement-Schatlo; V. Mlynarik; C. Cudalbu; D. Marino; I. Radovanovic et al. 

High-resolution spatial mapping of changes in the neurochemical profile after focal ischemia in mice

M. Alf; H. Lei; C. Berthet; L. Hirt; R. Gruetter et al. 

Impact of the prior knowledge on the quantification of in vivo 13C spectra using two different algorithms: LCModel and AMARES

C. R. Cudalbu; B. Lanz; J. M. Duarte; N. Kunz; R. Gruetter 

Effect of manganese chloride on the neurochemical profile of the rat hypothalamus

N. Just; C. R. Cudalbu; H. Lei; R. Gruetter 

Assessing The Importance Of An Astrocyte Specific Anaplerotic Enzyme In The Central Nervous System Of Rat

S. Lengacher; C. R. Cudalbu; N. Aznavour; R. Gruetter; P. Magistretti 

RETRACTED: Marker-independent identification of glioma-initiating cells

V. Clement; D. Marino; C. R. Cudalbu; M-F. Hamou; N. de Tribolet et al. 

In vivo Magnetic Resonance Spectroscopy (MRS) studies of brain metabolism during ammonia infusion

C. R. Cudalbu; B. Lanz; H. Frenkel; V. Mlynárik; R. Gruetter 

Scavenging Free Radicals To Preserve Enhancement and Extend Relaxation Times in NMR using Dynamic Nuclear Polarization

P. Miéville; P. Ahuja; R. Sarkar; S. Jannin; P. R. Vasos et al. 

Neurochemical profile of the mouse hypothalamus using in vivo1H MRS at 14.1T

H. Lei; C. Poitry-Yamate; F. Preitner; B. Thorens; R. Gruetter 

Direct in vivo measurement of glycine and the neurochemical profile in the rat medulla oblongata

L. Xin; G. Gambarota; J. M. N. Duarte; V. Mlynarik; R. Gruetter 

Diffusion-Weighted Spectroscopy: A Novel Approach to Determine Macromolecule Resonances in Short-Echo Time H-1-MRS

N. Kunz; C. R. Cudalbu; V. Mlynarik; P. S. Hueppi; S. V. Sizonenko et al. 

In vivo simultaneous measurement of glutamine synthetase and glutamate dehydrogenase activity in the hyperammonemic rat brain using localized 1H and 15N MRS

C. R. Cudalbu; B. Lanz; P. R. Vasos; Y. Pilloud; V. Mlynárik et al. 

Kinetics of Yttrium-Ligand Complexation Monitored Using Hyperpolarized 89Y as a Model for Gadolinium in Contrast Agents

P. Miéville; S. Jannin; L. Helm; G. Bodenhausen 

Biophysical Basis of the Diffusion-Weighted Magnetic Resonance Signal in the Rat Brain

Localized 31P saturation transfer in rat brain

V. Mlynarik; C. R. Cudalbu; Y. Pilloud; R. Gruetter 

Investigation of spatial distribution of metabolites in rat brain at elevated plasma glucose levels

V. Mlynarik; C. R. Cudalbu; H. Frenkel; N. Costers; R. Gruetter 

Feasibility of in vivo N-15 MRS detection of hyperpolarized N-15 labeled choline in rats

C. R. Cudalbu; A. Comment; F. Kurdzesau; R. van Heeswijk; K. Uffmann et al. 

Imaging glutamine synthesis rates in the hyperammonemic rat brain

C. R. Cudalbu; V. Mlynárik; B. Lanz; H. Frenkel; N. Costers et al. 

Hyperpolarizing Gases via Dynamic Nuclear Polarization and Sublimation

A. Comment; S. Jannin; J-N. Hyacinthe; P. Miéville; R. Sarkar et al. 

Some methods of dynamic nuclear polarization for use in metabolic imaging

Glutamine synthesis rate in the hyperammonaemic rat brain using simultaneous localized in vivo H-1 and N-15 MRS

C. R. Cudalbu; B. Lanz; F. Morgenthaler; Y. Pilloud; V. Mlynarik et al. 

Quantification of in vivo short echo-time proton magnetic resonance spectra at 14.1 T using two different approaches of modelling the macromolecule spectrum

C. R. Cudalbu; V. Mlynarik; L. Xin; R. Gruetter 

Hyperpolarized Lithium-6 as a Sensor of Nanomolar Contrast Agents

R. van Heeswijk; K. Uffmann; A. Comment; F. Kurdzesau; C. Perazzolo et al. 

Comparison of T-1 Relaxation Times of the Neurochemical Profile in Rat Brain at 9.4 Tesla and 14.1 Tesla

C. R. Cudalbu; V. Mlynarik; L. Xin; R. Gruetter 

Proton MRS investigation of human glioma models in nude mice at 14.1 T

V. Mlynarik; C. R. Cudalbu; V. Clément; D. Marino; I. Radovanovic et al. 

Simultaneous Localized in vivo 1H and 15N MRS of Glutamine Synthesis in the hyperammonaemic rat brain

C. R. Cudalbu; B. Lanz; F. D. Morgenthaler; Y. Pilloud; V. Mlynárik et al. 

Mapping glucose and lactate concentrations with microliter resolution in rat brain using short-echo-time spectroscopic imaging

V. Mlynarik; C. R. Cudalbu; H. Frenkel; R. Gruetter 

MEASUREMENT OF GLUTAMINE SYNTHESIS RATE IN THE HYPERAMMONAEMIC RAT BRAIN USING IN VIVO 1H AND 15N MRS

C. R. Cudalbu; B. Lanz; F. Morgenthaler; V. Mlynárik; R. Gruetter 

In vivo localized 15N and 1H MRS in the hyperammonaemic rat brain at 9.4T

C. R. Cudalbu; B. Lanz; F. Morgenthaler; Y. Pilloud; V. Mlynarik et al. 

Short-echo-time 1H MRS of the mouse lacking prion protein (Prnp-/-) at 14.1T

C. R. Cudalbu; V. Mlynárik; J. Bremer; A. Aguzzi; R. Gruetter 

MRS study of human glioma-initiating cells grown in the brain of nude Mice

V. Mlynarik; C. R. Cudalbu; V. Clément; I. Radovanovic; R. Gruetter 

Comparison of the T1 of the neurochemical profile in rat brain at 9.4T and 14.1T

C. R. Cudalbu; V. Mlynárik; L. Xin; R. Gruetter 

H-1 NMR spectroscopy of rat brain in vivo at 14.1 Tesla: Improvements in quantification of the neurochemical profile

V. Mlynarik; C. R. Cudalbu; L. Xin; R. Gruetter 

Comparison of two approaches to model the macromolecule spectrum for the quantification of short TE H-1 MRS spectra

C. R. Cudalbu; V. Mlynarik; L. Xin; R. Gruetter 

Comparison of Two Approaches to Model the Macromolecule Spectrum for the Quantification of Short TE 1H MRS Spectra at 14.1T

C. R. Cudalbu; V. Mlynárik; L. Xin; R. Gruetter 

Hahn T2 Relaxation Times of the Neurochemical Profile at 14.1T in the in vivo Rat Brain

L. Xin; G. Gambarota; C. R. Cudalbu; V. Mlynarik; R. Gruetter 

1H NMR T1 Relaxation Times of the Neurochemical Profiles in Rat Brain at 14.1T

C. R. Cudalbu; V. Mlynárik; L. Xin; R. Gruetter 

In Vivo Detection of Hyperpolarized 15N Choline in the Rat

C. R. Cudalbu; A. Comment; K. Uffmann; R. van Heeswijk; C. Perazzolo et al. 

Improved Spectral Dispersion in Proton MR Spectroscopy of the Neurochemical Profile in the Rat Brain at 14.1 Tesla

V. Mlynárik; C. R. Cudalbu; L. Xin; R. Gruetter 

MR study of a mouse model of implanted human glioma cells at 14.1T

C. R. Cudalbu; V. Mlynárik; V. Clement; I. Radovanovic; R. Gruetter