PUBLICATIONS

2025

Fast High-Resolution Metabolite Mapping in the rat Brain Using 1H-FID-MRSI at 14.1 T

D. Simicic; B. Alves; J. Mosso; R. B. van Heeswijk; G. Briand et al. 

NMR in biomedicine. 2025. Vol. 38, num. 2. DOI : 10.1002/nbm.5304.

2024

Noise-reduction techniques for 1H-FID-MRSI at 14.1 T: Monte Carlo validation and in vivo application

B. Alves; D. Simicic; J. Mosso; T. P. Lê; G. M. A. Briand et al. 

NMR in Biomedicine. 2024. Vol. 37, num. 11. DOI : 10.1002/nbm.5211.

Rescue of myocytes and locomotion through AAV2/9-2YF intracisternal gene therapy in a rat model of creatine transporter deficiency

G. Fernandes-Pires; M. D. Azevedo; M. Lanzillo; C. Roux-Petronelli; P-A. Binz et al. 

Molecular Therapy Methods & Clinical Development. 2024. Vol. 32, num. 2, p. 101251. DOI : 10.1016/j.omtm.2024.101251.

Diffusion of brain metabolites highlights altered brain microstructure in type C hepatic encephalopathy: a 9.4 T preliminary study

J. Mosso; G. Briand; K. Pierzchala; D. Simicic; A. Sierra et al. 

Frontiers In Neuroscience. 2024. Vol. 18, p. 1344076. DOI : 10.3389/fnins.2024.1344076.

Inhibition of urease-mediated ammonia production by 2-octynohydroxamic acid in hepatic encephalopathy

D. Evstafeva; F. Ilievski; Y. Bao; Z. Luo; B. Abramovic et al. 

Nature Communications. 2024. Vol. 15, num. 1, p. 2226. DOI : 10.1038/s41467-024-46481-8.

2023

Diffusion-weighted MR spectroscopy: Consensus, recommendations, and resources from acquisition to modeling

C. Ligneul; C. Najac; A. Doring; C. Beaulieu; F. Branzoli et al. 

Magnetic Resonance In Medicine. 2023. Vol. 91, num. 3, p. 860 – 885. DOI : 10.1002/mrm.29877.

Diffusion-weighted SPECIAL improves the detection of J-coupled metabolites at ultrahigh magnetic field

J. Mosso; D. Simicic; B. Lanz; R. Gruetter; C. Cudalbu 

Magnetic Resonance In Medicine. 2023. DOI : 10.1002/mrm.29805.

Editorial for the special issue on Brain Biochemistry in Liver Disease

C. Cudalbu; A. J. L. Cooper 

Analytical Biochemistry. 2023. Vol. 677, p. 115248. DOI : 10.1016/j.ab.2023.115248.

Age Dependence of Neurometabolic Changes in a Rat Pup Model of Type C Hepatic Encephalopathy

D. Simicic; V. Rackayova; O. Braissant; C. Toso; G. Oldani et al. 

2023. 20th Symposium of the International-Society-for-Hepatic-Encephalopathy-and-Nitrogen-Metabolism, Bad Zwischenahn, GERMANY, SEP 27-29, 2023. p. S24 – S24. DOI : 10.14309/01.ajg.0000948424.84976.19.

New Insights Into Brain Energy Metabolism in Type C Hepatic Encephalopathy: A Dual 18F-FDG PET and 9.4T 1H MRS Preclinical Study

J. Mosso; T. Yin; C. Poitry-Yamate; D. Simicic; M. Lepore et al. 

2023. 20th Symposium of the International-Society-for-Hepatic-Encephalopathy-and-Nitrogen-Metabolism, Bad Zwischenahn, GERMANY, SEP 27-29, 2023. p. S12 – S12. DOI : 10.14309/01.ajg.0000948348.20966.21.

The Beneficial Effect of Oral Cr Supplementation in an Early Childhood Rat Model of Chronic Hepatic Encephalopathy: In Vivo Longitudinal 1H and 31P Magnetic Resonance Spectroscopy Study

D. Simicic; O. Braissant; K. Pierzchala; S. Mitrea; D. Sessa et al. 

2023. 20th Symposium of the International-Society-for-Hepatic-Encephalopathy-and-Nitrogen-Metabolism, Bad Zwischenahn, GERMANY, SEP 27-29, 2023. p. S12 – S13. DOI : 10.14309/01.ajg.0000948352.71525.d3.

Brain Regional Differences in the Developing Brain Using an Animal Model of Type C Hepatic Encephalopathy

D. Simicic; K. Pierzchala; O. Braissant; C. Toso; G. Oldani et al. 

2023. 20th Symposium of the International-Society-for-Hepatic-Encephalopathy-and-Nitrogen-Metabolism, Bad Zwischenahn, GERMANY, SEP 27-29, 2023. p. S24 – S25. DOI : 10.14309/01.ajg.0000948428.52697.c3.

Evaluation of a Hydroxamate-Based Urease Inhibitor in a Rodent Model of Hepatic Encephalopathy

D. Evstafeva; F. Ilievski; Y. Bao; Z. Luo; B. Abramovic et al. 

2023. 20th Symposium of the International-Society-for-Hepatic-Encephalopathy-and-Nitrogen-Metabolism, Bad Zwischenahn, GERMANY, SEP 27-29, 2023. p. S30 – S31. DOI : 10.14309/01.ajg.0000948468.55577.45.

Lessons on brain edema in HE: from cellular to animal models and clinical studies

K. Pierzchala; A. Hadjihambi; J. Mosso; R. Jalan; C. F. F. Rose et al. 

Metabolic Brain Disease. 2023. DOI : 10.1007/s11011-023-01269-5.

Automated segmentation and labeling of subcutaneous mouse implants at 14.1T

J. Adda; G. Bioley; D. van de Ville; C. Cudalbu; M. G. Preti et al. 

Frontiers In Signal Processing. 2023. Vol. 3, p. 1155618. DOI : 10.3389/frsip.2023.1155618.

High field brain proton magnetic resonance spectroscopy and volumetry in children with chronic, compensated liver disease-A pilot study

C. Cudalbu; L. Xin; B. Marechal; S. Lachat; F. Zangas-Gheri et al. 

Analytical Biochemistry. 2023. Vol. 675, p. 115212. DOI : 10.1016/j.ab.2023.115212.

Neurometabolic changes in a rat pup model of type C hepatic encephalopathy depend on age at liver disease onset

D. Simicic; V. Rackayova; O. Braissant; C. Toso; G. Oldani et al. 

Metabolic Brain Disease. 2023. DOI : 10.1007/s11011-023-01210-w.

Central Nervous System Oxidative Stress interplay with inflammation in a rat model of Type C Hepatic Encephalopathy – brothers in arms?

K. Pierzchala; D. Simicic; A. Sienkiewicz; D. Sessa; S. Mitrea et al. 

2023. 1st international conference on the Future of Redox Biology, ITALY, Jun 17-19, 2022. p. S15 – S15. DOI : 10.1016/j.freeradbiomed.2022.12.056.

Harmonization of multi-scanner in vivo magnetic resonance spectroscopy: ENIGMA consortium task group considerations

A. D. Harris; H. Amiri; M. Bento; R. Cohen; C. R. K. Ching et al. 

Frontiers In Neurology. 2023. Vol. 13, p. 1045678. DOI : 10.3389/fneur.2022.1045678.

Neurometabolic profiles of bile duct ligated rats after the treatment with an urease inhibitor – 1H MRS dataset

D. Evstafeva; J-C. Leroux; C. R. Cudalbu; D. Simicic 

2023.

New insights into rodent brain microstructure and metabolism in hepatic encephalopathy

J. J. Mosso / R. Gruetter; C. R. Cudalbu (Dir.)  

Lausanne, EPFL, 2023. 

2022

MP-PCA denoising for diffusion MRS data: promises and pitfalls

J. Mosso; D. Simicic; K. Simsek; R. Kreis; C. Cudalbu et al. 

Neuroimage. 2022. Vol. 263, p. 119634. DOI : 10.1016/j.neuroimage.2022.119634.

Overview of oxidative stress findings in hepatic encephalopathy: From cellular and ammonium-based animal models to human data

D. Simicic; C. Cudalbu; K. Pierzchala 

Analytical Biochemistry. 2022. Vol. 654, p. 114795. DOI : 10.1016/j.ab.2022.114795.

Central Nervous System Oxidative Stress Interplay With Inflammation In A Rat Model Of Type C Hepatic Encephalopathy – Brothers In Arms?

P. Katarzyna; S. Dunja; S. Dario; M. Stefanita; B. Olivier et al. 

2022.  p. 40 – 40.

Abnormal brain oxygen homeostasis in an animal model of liver disease

A. Hadjihambi; C. Cudalbu; K. Pierzchala; D. Simicic; C. Donnelly et al. 

Jhep Reports. 2022. Vol. 4, num. 8, p. 100509. DOI : 10.1016/j.jhepr.2022.100509.

PET CMRglc mapping and H-1-MRS show altered glucose uptake and neurometabolic profiles in BDL rats

J. Mosso; T. Yin; C. Poitry-Yamate; D. Simicic; M. Lepore et al. 

Analytical Biochemistry. 2022. Vol. 647, p. 114606. DOI : 10.1016/j.ab.2022.114606.

Quantitative FDG-PET and 1H-MRS reveal altered glucose uptake and neurometabolic profiles in BDL rats

J. Mosso; T. Yin; C. Poitry-Yamate; D. Simicic; M. Lepore et al. 

2022.  p. 57 – 58.

Central nervous system and systemic oxidative stress interplay with inflammation in a bile duct ligation rat model of type C hepatic encephalopathy (vol 178, pg 295, 2022)

K. Pierzchala; D. Simicic; A. Sienkiewicz; D. Sessa; S. Mitrea et al. 

Free Radical Biology And Medicine. 2022. Vol. 182, p. 289 – 289. DOI : 10.1016/j.freeradbiomed.2022.01.016.

Advanced metabolite mapping at ultra-high field using 1H-MRS, 1H-MRSI and macromolecules: applications in a rat model of type C hepatic encephalopathy

D. Simicic / R. Gruetter; C. R. Cudalbu (Dir.)  

Lausanne, EPFL, 2022. 

Central nervous system and systemic oxidative stress interplay with inflammation in a bile duct ligation rat model of type C hepatic encephalopathy

K. Pierzchala; D. Simicic; A. Sienkiewicz; D. Sessa; S. Mitrea et al. 

Free Radical Biology And Medicine. 2022. Vol. 178, p. 295 – 307. DOI : 10.1016/j.freeradbiomed.2021.12.011.

Creatine transporter-deficient rat model shows motor dysfunction, cerebellar alterations, and muscle creatine deficiency without muscle atrophy

L. Duran-Trio; G. Fernandes-Pires; J. Grosse; I. Soro-Arnaiz; C. Roux-Petronelli et al. 

Journal Of Inherited Metabolic Disease. 2022. Vol. 45, num. 2, p. 278 – 291. DOI : 10.1002/jimd.12470.

2021

A Standardized Brain Molecular Atlas: A Resource for Systems Modeling and Simulation

P. Shichkova; J. S. Coggan; H. Markram; D. Keller 

Frontiers In Molecular Neuroscience. 2021. Vol. 14, p. 604559. DOI : 10.3389/fnmol.2021.604559.

Probiotics combined with rifaximin influence the neurometabolic changes in a rat model of type C HE

E. Flatt; V. A. McLin; O. Braissant; K. Pierzchala; P. Mastromarino et al. 

Scientific Reports. 2021. Vol. 11, num. 1, p. 17988. DOI : 10.1038/s41598-021-97018-8.

Metabolic and transcriptomic profiles of glioblastoma invasion revealed by comparisons between patients and corresponding orthotopic xenografts in mice

C. Cudalbu; P. Bady; M. Lai; L. Xin; O. Gusyatiner et al. 

Acta Neuropathologica Communications. 2021. Vol. 9, num. 1, p. 133. DOI : 10.1186/s40478-021-01232-4.

In vivo macromolecule signals in rat brain 1 H‐MR spectra at 9.4T: Parametrization, spline baseline estimation, and T 2 relaxation times

D. Simicic; V. Rackayová; L. Xin; I. Tkáč; T. Borbath et al. 

Magnetic Resonance in Medicine. 2021. Vol. 86, num. 5, p. 2384 – 2401. DOI : 10.1002/mrm.28910.

The first knock-in rat model for glutaric aciduria type I allows further insights into pathophysiology in brain and periphery

M. G. Melo; N. Remacle; H-P. Cudre-Cung; C. Roux; M. Poms et al. 

Molecular Genetics And Metabolism. 2021. Vol. 133, num. 2, p. 157 – 181. DOI : 10.1016/j.ymgme.2021.03.017.

2021 ISHEN guidelines on animal models of hepatic encephalopathy

S. DeMorrow; C. Cudalbu; N. Davies; A. R. Jayakumar; C. F. Rose 

Liver International. 2021. Vol. 41, num. 7, p. 1474 – 1488. DOI : 10.1111/liv.14911.

Hyperpolarized C-13-glucose magnetic resonance highlights reduced aerobic glycolysis in vivo in infiltrative glioblastoma

M. Mishkovsky; O. Gusyatiner; B. Lanz; C. Cudalbu; I. Vassallo et al. 

Scientific Reports. 2021. Vol. 11, num. 1, p. 5771. DOI : 10.1038/s41598-021-85339-7.

Minimum Reporting Standards for in vivo Magnetic Resonance Spectroscopy (MRSinMRS): Experts’ consensus recommendations

A. Lin; O. Andronesi; W. Bogner; I-Y. Choi; E. Coello et al. 

Nmr In Biomedicine. 2021.  p. e4484. DOI : 10.1002/nbm.4484.

Probiotics improve the neurometabolic profile of rats with chronic cholestatic liver disease

V. Rackayova; E. Flatt; O. Braissant; J. Grosse; D. Capobianco et al. 

Scientific Reports. 2021. Vol. 11, num. 1, p. 2269. DOI : 10.1038/s41598-021-81871-8.

A new rat model of creatine transporter deficiency reveals behavioral disorder and altered brain metabolism

L. Duran-Trio; G. Fernandes-Pires; D. Simicic; J. Grosse; C. Roux-Petronelli et al. 

Scientific Reports. 2021. Vol. 11, num. 1, p. 1636. DOI : 10.1038/s41598-020-80824-x.

Late post‐natal neurometabolic development in healthy male rats using 1 H and 31 P Magnetic Resonance Spectroscopy

V. Račkayová; D. Simicic; G. Donati; O. Braissant; R. Gruetter et al. 

Journal of Neurochemistry. 2021. Vol. 157, num. 3, p. 508 – 519. DOI : 10.1111/jnc.15294.

2020

Contribution of macromolecules to brain H-1 MR spectra: Experts’ consensus recommendations

C. Cudalbu; K. L. Behar; P. K. Bhattacharyya; W. Bogner; T. Borbath et al. 

Nmr In Biomedicine. 2020.  p. e4393. DOI : 10.1002/nbm.4393.

Magnetic resonance spectroscopy in the rodent brain: Experts’ consensus recommendations

B. Lanz; A. Abaei; O. Braissant; I-Y. Choi; C. Cudalbu et al. 

Nmr In Biomedicine. 2020.  p. e4325. DOI : 10.1002/nbm.4325.

Terminology and concepts for the characterization of in vivo MR spectroscopy methods and MR spectra: Background and experts’ consensus recommendations

R. Kreis; V. Boer; I-Y. Choi; C. Cudalbu; R. A. de Graaf et al. 

Nmr In Biomedicine. 2020.  p. e4347. DOI : 10.1002/nbm.4347.

B(0)shimming for in vivo magnetic resonance spectroscopy: Experts’ consensus recommendations

C. Juchem; C. Cudalbu; R. A. de Graaf; R. Gruetter; A. Henning et al. 

Nmr In Biomedicine. 2020.  p. e4350. DOI : 10.1002/nbm.4350.

Longitudinal osmotic and neurometabolic changes in young rats with chronic cholestatic liver disease

V. Rackayova; O. Braissant; A-L. Rougemont; C. Cudalbu; V. A. McLin 

Scientific Reports. 2020. Vol. 10, num. 1, p. 7536. DOI : 10.1038/s41598-020-64416-3.

MP-PCA denoising dramatically improves SNR in large-sized MRS data: an illustration in diffusion-weighted MRS

I. Jelescu; J. Veraart; C. R. Cudalbu 

ISMRM 28th Annual Meeting & Exhibition, Paris, France, August 8-13, 2020.

2019

Reply to: “Magnetic resonance spectroscopy: A surrogate marker of hepatic encephalopathy?”

V. A. Mclin; O. Braissant; C. Cudalbu 

Journal of Hepatology. 2019. Vol. 71, num. 5, p. 1057 – 1057. DOI : 10.1016/j.jhep.2019.08.003.

Bile Acids And Ammonium Contribute To Changes In Dendritic Spine Distribution In An Organotypic Culture Of Rat Hippocampus

L. Giovannoni; M. Deroo; O. Braissant; H. Henry; C. R. Cudalbu et al. 

2019. Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD) / Liver Meeting, Boston, MA, Nov 08-12, 2019. p. 471A – 472A.

Brain Regional Susceptibility to Oxidative Stress in a Rat Model of Chronic Hepatic Encephalopathy: In-Vivo 1H MRS, Ex-Vivo ESR Spectroscopy and Histology Findings

K. Pierzchala; D. Simicic; V. Rackayova; D. Sessa; A. Sienkiewicz et al. 

2019. 18th International-Society-for-Hepatic-Encephalopathy-and-Nitrogen-Metabolism Meeting, Williamsburg, VA, Sep 12-15, 2019. p. S33 – S36. DOI : 10.14309/01.ajg.0000582248.03815.eb.

Longitudinal neurometabolic changes in the hippocampus of a rat model of chronic hepatic encephalopathy

O. Braissant; V. Rackayova; K. Pierzchala; J. Grosse; V. A. McLin et al. 

Journal Of Hepatology. 2019. Vol. 71, num. 3, p. 505 – 515. DOI : 10.1016/j.jhep.2019.05.022.

Hippocampal and Cerebellar Astrocytes Morphological Alterations in a Rat Model of Chronic Hepatic Encephalopathy

K. Pierzchala; D. Simicic; O. Braissant; V. A. McLin; C. Cudalbu 

2019. 18th International-Society-for-Hepatic-Encephalopathy-and-Nitrogen-Metabolism Meeting, Williamsburg, VA, Sep 12-15, 2019. p. S33 – S33.

Antibiotic Rifaximin for Treatment of Chronic Liver Disease-Induced HE: A Longitudinal In Vivo 1H-MRS Study of Brain Metabolism on BDL Rats

E. Flatt; O. Braissant; S. Mitrea; D. Sessa; R. Gruetter et al. 

2019. 18th International-Society-for-Hepatic-Encephalopathy-and-Nitrogen-Metabolism Meeting, Williamsburg, VA, Sep 12-15, 2019. p. S18 – S19. DOI : 10.14309/01.ajg.0000582120.59858.08.

In Vivo Longitudinal 1H MRS Study of Hippocampal, Cereberal and Striatal Metabolic Changes in the Adult Brain Using an Animal Model of Chronic Hepatic Encephalopathy

D. Simicic; K. Pierzchala; V. Rackayova; O. Braissant; S-O. Mitrea et al. 

2019. 18th International-Society-for-Hepatic-Encephalopathy-and-Nitrogen-Metabolism Meeting, Williamsburg, VA, Sep 12-15, 2019. p. S17 – S17. DOI : 10.14309/01.ajg.0000582108.29364.13.

Cholestasis Decreases Dendritic Spine Density in a Rat Hippocampal Organotypic Culture

L. Giovannoni; M. De Roo; O. Braissant; H. Henry; C. Cudalbu et al. 

2019. 18th International-Society-for-Hepatic-Encephalopathy-and-Nitrogen-Metabolism Meeting, Williamsburg, VA, Sep 12-15, 2019. p. S37 – S38. DOI : 10.14309/01.ajg.0000582272.41932.fe.

Probiotics Combined With Rifaximin for the Treatment of Chronic Hepatic Encephalopathy: A Longitudinal In Vivo 1H-MRS Study of Brain Metabolism Using BDL Rats

E. Flatt; O. Braissant; S. Mitrea; D. Sessa; P. Mastromarino et al. 

2019. 18th International-Society-for-Hepatic-Encephalopathy-and-Nitrogen-Metabolism Meeting, Williamsburg, VA, Sep 12-15, 2019. p. S19 – S19. DOI : 10.14309/01.ajg.0000582124.67482.93.

Neurometabolism in Grey Matter of Children With Chronic Liver Disease or Portosystemic Shunting: A 1H-MRS Study at 7T

C. Cudalbu; L. Xin; S. Lachat; N. Valenza; F. Zangas-Gehri et al. 

2019. 18th International-Society-for-Hepatic-Encephalopathy-and-Nitrogen-Metabolism Meeting, Williamsburg, VA, Sep 12-15, 2019. p. S31 – S32. DOI : 10.14309/01.ajg.0000582224.88567.2a.

Brain Edema in Chronic Hepatic Encephalopathy

C. Cudalbu; S. D. Taylor-Robinson 

Journal Of Clinical And Experimental Hepatology. 2019. Vol. 9, num. 3, p. 362 – 382. DOI : 10.1016/j.jceh.2019.02.003.

Neurochemical Modifications in the Hippocampus, Cortex and Hypothalamus of Mice Exposed to Long-Term High-Fat Diet

B. Lizarbe; A. F. Soares; S. Larsson; J. M. N. Duarte 

Frontiers In Neuroscience. 2019. Vol. 12, p. 985. DOI : 10.3389/fnins.2018.00985.

Methodological consensus on clinical proton MRS of the brain: Review and recommendations

M. Wilson; O. Andronesi; P. B. Barker; R. Bartha; A. Bizzi et al. 

Magnetic Resonance in Medicine. 2019. Vol. 82, num. 2, p. 527 – 550. DOI : 10.1002/mrm.27742.

2018

Metabolic And Transcriptional Profiles Of Gbm Invasion: Comparison Of Patients And Paired Patient Derived Xenografts Using1H Magnetic Resonance Spectroscopy And Imaging (7T And 14T) And Rna-Sequencing

M. Hegi; C. Cudalbu; P. Bady; M. Lai; L. Xin et al. 

2018. 23rd Annual Scientific Meeting and Education Day of the Society-for-Neuro-Oncology (SNO) / 3rd CNS Anticancer Drug Discovery and Development Conference, New Orleans, LA, Nov 14-18, 2018. p. 35 – 35.

In vivo characterization of brain metabolism by 1 H MRS, 13 C MRS and 18 FDG PET reveals significant glucose oxidation of invasively growing glioma cells

M. Lai; I. Vassallo; B. Lanz; C. Poitry-Yamate; M-F. Hamou et al. 

International Journal of Cancer. 2018. Vol. 143, num. 1, p. 127 – 138. DOI : 10.1002/ijc.31299.

Brain metabolism during Chronic Hepatic Encephalopathy studied by in vivo 1H and 31P MRS

V. Rackayová / R. Gruetter; C. R. Cudalbu (Dir.)  

Lausanne, EPFL, 2018. 

Probing perturbed hepatic metabolism in bile-duct-ligated rats with hyperpolarized 13C pyruvate and arginine

H. A. I. Yoshihara; D. Firsov; C. R. Cudalbu; R. Gruetter 

ISMRM 2018, Paris, France, June16-21, 2018.

In vivo (13)C MRS in the mouse brain at 14.1 Tesla and metabolic flux quantification under infusion of [1,6-(13)C2]glucose

M. Lai; B. Lanz; C. Poitry-Yamate; J. F. Romero; C. M. Berset et al. 

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2018. Vol. 38, num. 10, p. 1701 – 1714. DOI : 10.1177/0271678X17734101.

2017

Social isolation stress and chronic glutathione deficiency have a common effect on the glutamine-to-glutamate ratio and myo-inositol concentration in the mouse frontal cortex

A. Corcoba; R. Gruetter; K. Q. Do; J. M. N. Duarte 

Journal of neurochemistry. 2017. Vol. 142, num. 5, p. 767 – 775. DOI : 10.1111/jnc.14116.

Metabolic changes in developing brain due to chronic liver disease: an in vivo longitudinal and multiparametric study using P-31-MRS (magnetic resonance spectroscopy), P-31-Magnetization transfer and H-1-MRS

V. Rackayova; V. Mlynarik; C. Cudalbu 

2017. 28th International Symposium on Cerebral Blood Flow, Metabolism and Function / 13th International Conference on Quantification of Brain Function with PET, Int Soc Cerebral Blood Flow & Metab, Berlin, GERMANY, APR 01-04, 2017. p. 496 – 497.

Editorial for the special issue on introduction to in vivo Magnetic Resonance Spectroscopy (MRS): A method to non-invasively study metabolism

C. Cudalbu; A. J. L. Cooper 

Analytical Biochemistry. 2017. Vol. 529, p. 1 – 3. DOI : 10.1016/j.ab.2017.05.014.

MRS studies of neuroenergetics and glutamate/glutamine exchange in rats: Extensions to hyperammonemic models

B. Lanz; V. Rackayova; O. Braissant; C. Cudalbu 

Analytical biochemistry. 2017. Vol. 529, p. 245 – 269. DOI : 10.1016/j.ab.2016.11.021.

Creatine in the central nervous system: From magnetic resonance spectroscopy to creatine deficiencies

V. Rackayova; C. Cudalbu; P. J. W. Pouwels; O. Braissant 

Analytical biochemistry. 2017. Vol. 529, p. 144 – 157. DOI : 10.1016/j.ab.2016.11.007.

2016

Brain edema: a valid endpoint for measuring hepatic encephalopathy?

C. Bémeur; C. Cudalbu; G. Dam; A. S. Thrane; A. J. L. Cooper et al. 

Metabolic brain disease. 2016. Vol. 31, num. 6, p. 1249 – 1258. DOI : 10.1007/s11011-016-9843-9.

(1)H and (31)P magnetic resonance spectroscopy in a rat model of chronic hepatic encephalopathy: in vivo longitudinal measurements of brain energy metabolism

V. Rackayova; O. Braissant; V. A. McLin; C. Berset; B. Lanz et al. 

Metabolic brain disease. 2016. Vol. 31, num. 6, p. 1303 – 1314. DOI : 10.1007/s11011-015-9715-8.

Hyperpolarized 6Li as a probe for hemoglobin oxygenation level

R. Balzan; M. Mishkovsky; Y. Simonenko; R. B. van Heeswijk; R. Gruetter et al. 

Contrast Media and Molecular Imaging. 2016. Vol. 11, num. 1, p. 41 – 46. DOI : 10.1002/cmmi.1656.

2015

In Vivo Longitudinal (1)H MRS Study of Transgenic Mouse Models of Prion Disease in the Hippocampus and Cerebellum at 14.1 T

C. Cudalbu; M. Craveiro; V. Mlynárik; J. Bremer; A. Aguzzi et al. 

Neurochemical research. 2015. Vol. 40, num. 12, p. 2639 – 2646. DOI : 10.1007/s11064-015-1643-9.

2014

Is the macromolecule signal tissue-specific in healthy human brain? A 1H MRS study at 7 tesla in the occipital lobe

B. Schaller; L. Xin; R. Gruetter 

Magnetic Resonance in Medicine. 2014. Vol. 72, num. 2, p. 934 – 940. DOI : 10.1002/mrm.24995.

In vivo 13C MRS in the mouse brain at 14.1 T and metabolic flux quantification during infusion of [1,6-13C2] Glucose

M. Lai; B. Lanz; C. J. d. C. Romero; C. R. Cudalbu; R. Gruetter 

2014. International Society for Magnetic Resonance in Medicine, Milan, May 10-16, 2014.

Neurochemical profile differentiation of glioma induced by cancer stem cells expressing WIF1: a 1H-MRS longitudinal study at 14.1T

M. Lai; C. R. Cudalbu; B. Lanz; I. Vassallo; M-F. Hamou et al. 

2014. International Society for Magnetic Resonance in Medicine, Milan, May 10-16, 2014.

Hyperpolarization of Deuterated Metabolites via Remote Cross-Polarization and Dissolution Dynamic Nuclear Polarization

B. Vuichoud; J. Milani; A. Bornet; R. Melzi; S. Jannin et al. 

The Journal of Physical Chemistry B. 2014. Vol. 118, num. 5, p. 1411 – 1415. DOI : 10.1021/jp4118776.

In vivo brain macromolecule signals in healthy and glioblastoma mouse models: 1H magnetic resonance spectroscopy, post-processing and metabolite quantification at 14.1 T

M. Craveiro; V. Clément-Schatlo; D. Marino; R. Gruetter; C. Cudalbu 

Journal of Neurochemistry. 2014. Vol. 129, num. 5, p. 806 – 815. DOI : 10.1111/jnc.12673.

Optimized MEGA-SPECIAL for in vivo glutamine detection in the rat brain at 14.1 T

M. Craveiro; C. Cudalbu; V. Mlynárik; R. Gruetter 

NMR in Biomedicine. 2014. Vol. 27, num. 10, p. 1151 – 1158. DOI : 10.1002/nbm.3168.

Cross polarization from H-1 to quadrupolar Li-6 nuclei for dissolution DNP

A. J. P. Linde; A. Bornet; J. Milani; B. Vuichoud; R. Melzi et al. 

Physical Chemistry Chemical Physics. 2014. Vol. 16, num. 45, p. 24813 – 24817. DOI : 10.1039/c4cp03592e.

Studying glioblastoma progression in a rat model of human glioma initiating cells using 1H MRS and DTI

M. Mishkovsky; C. R. Cudalbu; E. Can; D. Mario; I. Radovanovic et al. 

2014. International Society for Magnetic Resonance in Medicine, Milano, Italy, 2014.

Clinical Proton MR Spectroscopy in Central Nervous System Disorders

G. Öz; J. R. Alger; P. B. Barker; R. Bartha; A. Bizzi et al. 

Radiology. 2014. Vol. 270, num. 3, p. 658 – 679. DOI : 10.1148/radiol.13130531.

2013

Hepatic encephalopathy and brain metabolism: a longitudinal in vivo study

C. Cudalbu; V. McLin; O. Braissant 

2013. 24th Biennial Meeting of the International-Society-for-Neurochemistry and the American-Society-for-Neurochemistry, Cancun, MEXICO, APR 20-24, 2013. p. 178 – 179.

Methods for Molecular Magnetic Resonance Imaging and Magnetic Resonance Spectroscopy using Hyperpolarized Nuclei

R. Balzan / A. Comment; R. Gruetter (Dir.)  

Lausanne, EPFL, 2013. 

The C57BL/6 mouse exhibits sporadic congenital portosystemic shunts

C. Cudalbu; V. McLin; H. Lei; J. Duarte; A. Rougemont et al. 

2013. 24th Biennial Meeting of the International-Society-for-Neurochemistry and the American-Society-for-Neurochemistry, Cancun, MEXICO, APR 20-24, 2013. p. 107 – 108.

Ammonia toxicity to the brain

O. Braissant; V. A. McLin; C. Cudalbu 

Journal of inherited metabolic disease. 2013. Vol. 36, num. 4, p. 595 – 612. DOI : 10.1007/s10545-012-9546-2.

In vivo studies of brain metabolism in animal models of Hepatic Encephalopathy using (1)H Magnetic Resonance Spectroscopy

C. Cudalbu 

Metabolic brain disease. 2013. Vol. 28, num. 2, p. 167 – 174. DOI : 10.1007/s11011-012-9368-9.

The C57BL/6J Mouse Exhibits Sporadic Congenital Portosystemic Shunts

C. Cudalbu; V. A. Mclin; H. Lei; J. M. N. Duarte; A-L. Rougemont et al. 

PLoS ONE. 2013. Vol. 8, num. 7, p. e69782. DOI : 10.1371/journal.pone.0069782.

Which prior knowledge? Quantification of in vivo brain (13) C MR spectra following (13) C glucose infusion using AMARES

B. Lanz; J. M. N. Duarte; N. Kunz; V. Mlynárik; R. Gruetter et al. 

Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 2013. Vol. 69, num. 6, p. 1512 – 1522. DOI : 10.1002/mrm.24406.

Differences in CNS metabolism between pups and adults in an animal model of biliary cirrhosis: longitudinal, non-invasive in vivo study

C. Cudalbu; O. Braissant; V. A. Mclin 

2013. The 64th Annual Meeting of the American Association for the Study of Liver Diseases: The Liver Meeting 2013, Washington, DC, November 1 – 5, 2013.

Single spin-echo T 2 relaxation times of cerebral metabolites at 14.1 T in the in vivo rat brain

L. Xin; G. Gambarota; C. Cudalbu; V. Mlynárik; R. Gruetter 

Magma (New York, N.Y.). 2013. Vol. 26, num. 6, p. 549 – 554. DOI : 10.1007/s10334-013-0378-3.

Brain metabolism in rat model of human glioma initiating cells

M. Mishkovsky; C. R. Cudalbu; A. Comment; D. Mario; I. Radovanovic et al. 

2013. International Society for Magnetic Resonance in Medicine, Salt Lake City, USA, April 2013.

Quantification of the neurochemical profile using simulated macromolecule resonances at 3 T

B. Schaller; L. Xin; C. Cudalbu; R. Gruetter 

NMR in biomedicine. 2013. Vol. 26, num. 5, p. 593 – 599. DOI : 10.1002/nbm.2896.

Differences in CNS metabolism between pups and adults in an animal model of biliary cirrhosis: longitudinal, non-invasive in vivo study

C. Cudalbu; O. Braissant; V. A. Mclin 

2013. 64th Annual Meeting and Postgraduate Course of the American-Association-for-the-Study-of-Liver-Diseases. p. 803A – 803A.

In vivo brain energy metabolism in a rat model of chronic Hepatic Encephalopathy using 31P MRS

C. Cudalbu; O. Braissant; A. Jayaswal; R. Gruetter; V. A. McLin 

2013. The 64th Annual Meeting of the American Association for the Study of Liver Diseases: The Liver Meeting 2013, Washington, DC, November 1 – 5, 2013.

The C57BL/6 mouse exhibits sporadic congenital portosystemic shunts

C. R. Cudalbu; V. McLin; H. Lei; J. das Neves Duarte; A-L. Rougemont et al. 

ISMRM.

Proton T(1) relaxation times of metabolites in human occipital white and gray matter at 7 T

L. Xin; B. Schaller; V. Mlynarik; H. Lu; R. Gruetter 

Magnetic Resonance in Medicine. 2013. Vol. 69, num. 4, p. 931 – 936. DOI : 10.1002/mrm.24352.

In vivo brain energy metabolism in a rat model of chronic Hepatic Encephalopathy using 31P MRS

C. Cudalbu; O. Braissant; A. Jayaswal; R. Gruetter; V. A. Mclin 

2013. 64th Annual Meeting and Postgraduate Course of the American-Association-for-the-Study-of-Liver-Diseases’, u’64th Annual Meeting and Postgraduate Course of the American-Association-for-the-Study-of-Liver-Diseases’. p. 393A – 393A.

In vivo and longitudinal assessment of brain metabolism in Hepatic Encephalopathy using 1H MRS

C. R. Cudalbu; V. McLin; O. Braissant; R. Gruetter 

ISMRM.

2012

Proton and phosphorus magnetic resonance spectroscopy of a mouse model of Alzheimer’s disease

V. Mlynárik; M. Cacquevel; L. Sun-Reimer; S. Janssens; C. Cudalbu et al. 

Journal of Alzheimer’s disease : JAD. 2012. Vol. 31, p. S87 – 99. DOI : 10.3233/JAD-2012-112072.

Phosphorus MRS Study of a Murine Model of Peripheral Arterial Disease

V. Mlynárik; M. Pellegrin; C. R. Cudalbu; L. Mazzolai; R. Gruetter 

2012. ISMRM 20th Annual Scientific Meeting, Melbourne, Australia, 5-11 May 2012.

QUANTIFICATION DIFFERENCES OF 1H SPECTRA IN HUMAN BRAIN AT 3 TESLA USING THE ACQUIRED MACROMOLECULE BASELINE OR THE BUILT-IN LCMODEL SPLINE BASELINE

B. Schaller; X. Liu; R. Gruetter 

2012. ISMRM 2012, Melbourne, May 2012.

Cerebral glutamine metabolism under hyperammonemia determined in vivo by localized H-1 and N-15 NMR spectroscopy

C. R. Cudalbu; B. Lanz; J. M. N. Duarte; F. D. Morgenthaler; Y. Pilloud et al. 

Journal Of Cerebral Blood Flow And Metabolism. 2012. Vol. 32, p. 696 – 708. DOI : 10.1038/jcbfm.2011.173.

Assessment Of Cerebral Osmotic Regulation In A Rat Model Of Biliary Cirrhosis Using MR Spectroscopy

V. A. McLin; O. Braissant; Y. van de Looij; N. Kunz; R. Gruetter et al. 

2012. 47th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL), Barcelona, SPAIN, Apr 18-22, 2012. p. S231 – S232.

Localized in vivo hyperpolarization transfer sequences

M. Mishkovsky; T. Cheng; A. Comment; R. Gruetter 

Magnetic Resonance in Medicine. 2012. Vol. 68, num. 2, p. 349 – 352. DOI : 10.1002/mrm.23231.

Handling macromolecule signals in the quantification of the neurochemical profile

C. Cudalbu; V. Mlynárik; R. Gruetter 

Journal of Alzheimer’s disease : JAD. 2012. Vol. 31, p. S101 – 15. DOI : 10.3233/JAD-2012-120100.

The neurochemical profile quantified by in vivo(1)H NMR spectroscopy

J. M. N. Duarte; H. Lei; V. Mlynárik; R. Gruetter 

NeuroImage. 2012. Vol. 61, num. 2, p. 342 – 62. DOI : 10.1016/j.neuroimage.2011.12.038.

In vivo longitudinal 1H Spectroscopic Imaging and Diffusion Tensor Imaging studies at 9.4T in a rat model of chronic liver failure

C. R. Cudalbu; V. McLin; O. Braissant; N. Kunz; Y. Van de Looij et al. 

ISMRM 20th Annual Scientific Meeting, 5-11 May 2012, Melbourne, Australia.

Brain osmolytes and brain edema in a rat model of chronic liver failure: in vivo longitudinal 1H Spectroscopic imaging and Diffusion tensor imaging studies at 9.4T

C. R. Cudalbu; O. Braissant; M. Lepore; R. Gruetter; V. McLin 

The 15th International Society of Hepatic Encephalopathy and Nitrogen Metabolism, Symposium May 29 – June 2, 2012, Denmark.

In vivo longitudinal 1H Spectroscopic Imaging and Diffusion Tensor Imaging studies at 9.4T in a rat model of chronic liver failure

C. R. Cudalbu; V. McLin; O. Braissant; N. Kunz; Y. van de Looij et al. 

2012. ISMRM 20th Annual Scientific Meeting, Melbourne, Australia, 5-11 May 2012.

In vivo metabolic profiling of glioma-initiating cells using proton magnetic resonance spectroscopy at 14.1 Tesla

V. Mlynarik; C. R. Cudalbu; V. Clement; D. Marino; I. Radovanovic et al. 

Nmr In Biomedicine. 2012. Vol. 25, p. 506 – 513. DOI : 10.1002/nbm.1763.

2011

In vivo longitudinal 1H MRS study of transgenic mouse models of prion disease in the hippocampus and cerebellum at 14.1T

C. R. Cudalbu; M. Craveiro; V. Mlynárik; J. Bremer; A. Aguzzi et al. 

2011. ISMRM 19th Annual Scientific Meeting, Montreal, Canada, 7-13 May 2011.

In vivo localized 15N MRS detection of hyperpolarized 15N labeled choline in the rat brain

C. R. Cudalbu; A. Comment; T. Cheng; M. Mishkovsky; R. Gruetter 

2011. ISMRM 19th Annual Scientific Meeting, Montreal, Canada, 7-13 May 2011.

Imaging the in vivo effect of hyperammonemia in the rat brain: a Spectroscopic Imaging and Diffusion Tensor Imaging study

C. R. Cudalbu; N. Kunz; B. Lanz; Y. van de Looij; V. Mlynárik et al. 

2011. BRAIN’11 & BRAINPET’11, Barcelona, Spain, 24-28 May 2011.

Effect of manganese chloride on the neurochemical profile of the rat hypothalamus

N. Just; C. R. Cudalbu; H. Lei; R. Gruetter 

Journal of Cerebral Blood Flow and Metabolism. 2011. Vol. 31, num. 12, p. 2324 – 2333. DOI : 10.1038/jcbfm.2011.92.

Assessing The Importance Of An Astrocyte Specific Anaplerotic Enzyme In The Central Nervous System Of Rat

S. Lengacher; C. R. Cudalbu; N. Aznavour; R. Gruetter; P. Magistretti 

2011. 10th European Meeting on Glial Cells in Health and Disease, Prague, CZECH REPUBLIC, Sep 13-17, 2011. p. S109 – S110.

High-resolution spatial mapping of changes in the neurochemical profile after focal ischemia in mice

M. Alf; H. Lei; C. Berthet; L. Hirt; R. Gruetter et al. 

2011. 19th Scientific Meeting of the International Society for Magnetic Resonance in Medicine, Montréal, Québec, Canada, 7-13 May 2011.

In vivo metabolic profiling of glioma-initiating cells using proton magnetic resonance spectroscopy at 14.1 Tesla

V. Clement-Schatlo; V. Mlynarik; C. Cudalbu; D. Marino; I. Radovanovic et al. 

2011.  p. S15 – S15.

Impact of the prior knowledge on the quantification of in vivo 13C spectra using two different algorithms: LCModel and AMARES

C. R. Cudalbu; B. Lanz; J. M. Duarte; N. Kunz; R. Gruetter 

2011. ISMRM 19th Annual Scientific Meeting, Montreal, Canada, 7-13 May 2011.

High-resolution mapping of the neurochemical profile after focal ischemia in mice

M. Alf; H. Lei; C. Berthet; L. Hirt; R. Gruetter et al. 

2011. ISMRM 19th Annual Meeting & Exhibition, Montreal, Canada, May 7-13, 2011.

2010

RETRACTED: Marker-independent identification of glioma-initiating cells

V. Clement; D. Marino; C. R. Cudalbu; M-F. Hamou; N. de Tribolet et al. 

Nature Methods. 2010. Vol. 7, p. 224 – U88. DOI : 10.1038/NMETH.1430.

Neurochemical profile of the mouse hypothalamus using in vivo1H MRS at 14.1T

H. Lei; C. Poitry-Yamate; F. Preitner; B. Thorens; R. Gruetter 

Nmr in Biomedicine. 2010. Vol. 23, num. 6, p. 578 – 583. DOI : 10.1002/nbm.1498.

Kinetics of Yttrium-Ligand Complexation Monitored Using Hyperpolarized 89Y as a Model for Gadolinium in Contrast Agents

P. Miéville; S. Jannin; L. Helm; G. Bodenhausen 

Journal of the American Chemical Society. 2010. Vol. 132, num. 14, p. 5006 – 5007. DOI : 10.1021/ja1013954.

Biophysical Basis of the Diffusion-Weighted Magnetic Resonance Signal in the Rat Brain

N. Kunz / R. Gruetter (Dir.)  

Lausanne, EPFL, 2010. 

In vivo simultaneous measurement of glutamine synthetase and glutamate dehydrogenase activity in the hyperammonemic rat brain using localized 1H and 15N MRS

C. R. Cudalbu; B. Lanz; P. R. Vasos; Y. Pilloud; V. Mlynárik et al. 

2010. ISMRM-ESMRMB joint Annual Meeting, Stockholm, Sweden, 1-7 May, 2010.

Scavenging Free Radicals To Preserve Enhancement and Extend Relaxation Times in NMR using Dynamic Nuclear Polarization

P. Miéville; P. Ahuja; R. Sarkar; S. Jannin; P. R. Vasos et al. 

Angewandte Chemie International Edition. 2010. Vol. 49, p. 6182 – 6185. DOI : 10.1002/anie.201000934.

Diffusion-Weighted Spectroscopy: A Novel Approach to Determine Macromolecule Resonances in Short-Echo Time H-1-MRS

N. Kunz; C. R. Cudalbu; V. Mlynarik; P. S. Hueppi; S. V. Sizonenko et al. 

Magnetic Resonance In Medicine. 2010. Vol. 64, p. 939 – 946. DOI : 10.1002/mrm.22490.

Hyperpolarizing Gases via Dynamic Nuclear Polarization and Sublimation

A. Comment; S. Jannin; J-N. Hyacinthe; P. Miéville; R. Sarkar et al. 

Physical Review Letters. 2010. Vol. 105, num. 1, p. 018104. DOI : 10.1103/PhysRevLett.105.018104.

Direct in vivo measurement of glycine and the neurochemical profile in the rat medulla oblongata

L. Xin; G. Gambarota; J. M. N. Duarte; V. Mlynarik; R. Gruetter 

Nmr In Biomedicine. 2010. Vol. 23, p. 1097 – 1102. DOI : 10.1002/nbm.1537.

Investigation of spatial distribution of metabolites in rat brain at elevated plasma glucose levels

V. Mlynarik; C. R. Cudalbu; H. Frenkel; N. Costers; R. Gruetter 

2010. ISMRM-ESMRMB joint Annual Meeting, Stockholm, Sweden, 1-7 May, 2010.

Imaging glutamine synthesis rates in the hyperammonemic rat brain

C. R. Cudalbu; V. Mlynárik; B. Lanz; H. Frenkel; N. Costers et al. 

2010. ISMRM-ESMRMB joint Annual Meeting, Stockholm, Sweden, 1-7 May, 2010.

Localized 31P saturation transfer in rat brain

V. Mlynarik; C. R. Cudalbu; Y. Pilloud; R. Gruetter 

2010. ISMRM-ESMRMB joint Annual Meeting, Stockholm, Sweden, 1-7 May, 2010.

Feasibility of in vivo N-15 MRS detection of hyperpolarized N-15 labeled choline in rats

C. R. Cudalbu; A. Comment; F. Kurdzesau; R. van Heeswijk; K. Uffmann et al. 

Physical Chemistry Chemical Physics. 2010. Vol. 12, num. 22, p. 5818 – 5823. DOI : 10.1039/c002309b.

In vivo Magnetic Resonance Spectroscopy (MRS) studies of brain metabolism during ammonia infusion

C. R. Cudalbu; B. Lanz; H. Frenkel; V. Mlynárik; R. Gruetter 

2010. 9th International Conference on Brain Energy Metabolism, Budapest, 7-10 July 2010.

2009

Comparison of T-1 Relaxation Times of the Neurochemical Profile in Rat Brain at 9.4 Tesla and 14.1 Tesla

C. R. Cudalbu; V. Mlynarik; L. Xin; R. Gruetter 

Magnetic Resonance In Medicine. 2009. Vol. 62, p. 862 – 867. DOI : 10.1002/mrm.22022.

Proton MRS investigation of human glioma models in nude mice at 14.1 T

V. Mlynarik; C. R. Cudalbu; V. Clément; D. Marino; I. Radovanovic et al. 

2009. ISMRM 17th Annual Scientific Meeting, Hawaii, 18-19 April 2009.

Glutamine synthesis rate in the hyperammonaemic rat brain using simultaneous localized in vivo H-1 and N-15 MRS

C. R. Cudalbu; B. Lanz; F. Morgenthaler; Y. Pilloud; V. Mlynarik et al. 

2009. 24th International Symposium on Cerebral Blood Flow and Metabolism/9th International Conference on Quantification of Brain Function with PET, Chicago, IL, Jun 29-Jul 03, 2009. p. S609 – S610.

Quantification of in vivo short echo-time proton magnetic resonance spectra at 14.1 T using two different approaches of modelling the macromolecule spectrum

C. R. Cudalbu; V. Mlynarik; L. Xin; R. Gruetter 

Measurement Science & Technology. 2009. Vol. 20, num. 10, p. 104034. DOI : 10.1088/0957-0233/20/10/104034.

MEASUREMENT OF GLUTAMINE SYNTHESIS RATE IN THE HYPERAMMONAEMIC RAT BRAIN USING IN VIVO 1H AND 15N MRS

C. R. Cudalbu; B. Lanz; F. Morgenthaler; V. Mlynárik; R. Gruetter 

2009. INTERNATIONAL SYMPOSIUM ON HEPATIC ENCEPHALOPATHY, Valencia, Spain, September 17-19.

Short-echo-time 1H MRS of the mouse lacking prion protein (Prnp-/-) at 14.1T

C. R. Cudalbu; V. Mlynárik; J. Bremer; A. Aguzzi; R. Gruetter 

2009. ISMRM 17th Annual Scientific Meeting, Hawaii, 18-19 April 2009.

Some methods of dynamic nuclear polarization for use in metabolic imaging

F. Kurdzesau / J. v. d. Klink; A. Comment (Dir.)  

Lausanne, EPFL, 2009. 

Simultaneous Localized in vivo 1H and 15N MRS of Glutamine Synthesis in the hyperammonaemic rat brain

C. R. Cudalbu; B. Lanz; F. D. Morgenthaler; Y. Pilloud; V. Mlynárik et al. 

2009. ISMRM 17th Annual Scientific Meeting, Hawaii, 18-19 April.

In vivo localized 15N and 1H MRS in the hyperammonaemic rat brain at 9.4T

C. R. Cudalbu; B. Lanz; F. Morgenthaler; Y. Pilloud; V. Mlynarik et al. 

2009. ESMRMB, Antalya, TR, October 1-3.

Mapping glucose and lactate concentrations with microliter resolution in rat brain using short-echo-time spectroscopic imaging

V. Mlynarik; C. R. Cudalbu; H. Frenkel; R. Gruetter 

2009. ISMRM 17th Annual Scientific Meeting, Hawaii, 18-19 April 2009.

Hyperpolarized Lithium-6 as a Sensor of Nanomolar Contrast Agents

R. van Heeswijk; K. Uffmann; A. Comment; F. Kurdzesau; C. Perazzolo et al. 

Magnetic Resonance In Medicine. 2009. Vol. 61, p. 1489 – 1493. DOI : 10.1002/mrm.21952.

2008

Comparison of two approaches to model the macromolecule spectrum for the quantification of short TE H-1 MRS spectra

C. R. Cudalbu; V. Mlynarik; L. Xin; R. Gruetter 

2008. IEEE International Workshop on Imaging Systems and Techniques, Chania, GREECE, Sep 10-12, 2008. p. 309 – 312. DOI : 10.1109/IST.2008.4659991.

MRS study of human glioma-initiating cells grown in the brain of nude Mice

V. Mlynarik; C. R. Cudalbu; V. Clément; I. Radovanovic; R. Gruetter 

2008. 25th Annual Scientific Meeting of ESMRMB, Valencia, Spain,

H-1 NMR spectroscopy of rat brain in vivo at 14.1 Tesla: Improvements in quantification of the neurochemical profile

V. Mlynarik; C. R. Cudalbu; L. Xin; R. Gruetter 

Journal of Magnetic Resonance. 2008. Vol. 194, p. 163 – 168. DOI : 10.1016/j.jmr.2008.06.019.

Comparison of the T1 of the neurochemical profile in rat brain at 9.4T and 14.1T

C. R. Cudalbu; V. Mlynárik; L. Xin; R. Gruetter 

2008. 25th Annual Scientific Meeting of ESMRMB, Valencia, Spain, 2008.

Improved Spectral Dispersion in Proton MR Spectroscopy of the Neurochemical Profile in the Rat Brain at 14.1 Tesla

V. Mlynárik; C. R. Cudalbu; L. Xin; R. Gruetter 

2008. 16th Annual ISMRM Meeting, Toronto, May 2008.

In Vivo Detection of Hyperpolarized 15N Choline in the Rat

C. R. Cudalbu; A. Comment; K. Uffmann; R. van Heeswijk; C. Perazzolo et al. 

2008. 16th Annual ISMRM Meeting, Toronto, May 2008.

Comparison of Two Approaches to Model the Macromolecule Spectrum for the Quantification of Short TE 1H MRS Spectra at 14.1T

C. R. Cudalbu; V. Mlynárik; L. Xin; R. Gruetter 

2008. 16th Annual ISMRM Meeting, Toronto, May 2008.

1H NMR T1 Relaxation Times of the Neurochemical Profiles in Rat Brain at 14.1T

C. R. Cudalbu; V. Mlynárik; L. Xin; R. Gruetter 

2008. 16th Annual ISMRM Meeting, Toronto, May 2008.

Hahn T2 Relaxation Times of the Neurochemical Profile at 14.1T in the in vivo Rat Brain

L. Xin; G. Gambarota; C. R. Cudalbu; V. Mlynarik; R. Gruetter 

2008. ISMRM 16th Scientific Meeting & Exhibition, Toronto, Ontario, Canada, May 3-9, 2008.

2007

MR study of a mouse model of implanted human glioma cells at 14.1T

C. R. Cudalbu; V. Mlynárik; V. Clement; I. Radovanovic; R. Gruetter 

2007. Changins “Neuroscience” meeting, Switzerland, 2007-11-21.