Jessie Mosso graduated from an engineering school in France and obtained a master’s degree in Physics (ESPCI Paris) and in Neuroscience (Sorbonne Université, Paris) in 2019. During her graduate studies, she conducted research projects on the topic of dissolution dynamic nuclear polarization (d-DNP) at UC San Francisco and École Normale Supérieure, Paris.
Jessie joined EPFL in September 2019 to start a PhD in the CIBM and LIFMET under the supervision of Dr. Cristina Cudalbu and Prof. Rolf Gruetter. Her thesis research consists in the implementation of diffusion weighted spectroscopy (DWS) and imaging (DWI) at 14.1T to probe brain microstructure alterations in a preclinical model of hepatic encephalopathy (HE). Subprojects of her thesis involve FDG-PET imaging to study energy metabolism in chronic hepatic encephalopathy and validations of PCA denoising techniques for MRS data.
She defended her PhD thesis in 2023, and continued to pursue her research interests as a CIBM research staff till mid-2024. In 2024 Jessie became a Postdoctoral Research Fellow at New York University Grossman School of Medicine.
PhD Thesis
New insights into rodent brain microstructure and metabolism in hepatic encephalopathy
Metabolite-cycling at 14.1T using SPECIAL and diffusion-weighted SPECIAL @ ISMRM 2024 – Summa Cum Laude Merit Award
Improved glutamine detection using diffusion-weighted SPECIAL at 14.1T @ISMRM 2023
Diffusion MRI and MRS probe cerebellar microstructure alterations in the rat developing brain during hepatic encephalopathy @ISMRM 2022
Diffusion-weighted magnetic resonance spectroscopy in the cerebellum of a rat model of hepatic encephalopathy at 14.1T @ISMRM 2021 Magna Cum Laude Merit Award
Multimodal assessment of brain energy metabolism in a rat model of hepatic encephalopathy using 1H-MRS and 18F-FDG PET – a pilot study @ISMRM 2020
New insights into brain energy metabolism in type C hepatic encephalopathy: a dual 18F-FDG PET and 9.4T 1H MRS preclinical study @CIBM Breakfast and Science Seminar
Publications
MRS4Brain: a processing toolbox for preclinical MR spectroscopy and spectroscopic imaging data
2025
Ex vivo brain MRI to assess conventional and FLASH brain irradiation effects
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 2025. Vol. 208. DOI : 10.1016/j.radonc.2025.110894.Differentiating unirradiated mice from those exposed to conventional or FLASH radiotherapy using MRI
2025