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2025
Journal Articles
Lumen charge governs gated ion transport in β-barrel nanopores
Nature Nanotechnology. 2025. DOI : 10.1038/s41565-025-02052-6.Synthetic α-synuclein fibrils replicate in mice causing MSA-like pathology
Nature. 2025. DOI : 10.1038/s41586-025-09698-1.The Denseness of the Closure of Some Nyman–Beurling Linear Manifolds Implies the Absence of Zeroes of Certain Combinations of Riemann Zeta-Functions in the Critical Strip
Symmetry. 2025. Vol. 17, num. 9. DOI : 10.3390/sym17091391.Nanomotion-Based Drug Sensitivity Prediction in Ovarian and Colon Cancer Cell Lines Using Machine Learning
ACS Pharmacology & Translational Science. 2025. DOI : 10.1021/acsptsci.5c00312.Rapid assessment of bisphenol A toxicity on fish eggs using optical nanomotion detection
Environmental Toxicology and Chemistry. 2025. DOI : 10.1093/etojnl/vgaf165.Phase Contrast 4D-STEM Tomography of Thick Biological Specimens
Microscopy and Microanalysis. 2025. Vol. 31, num. Supplement_1. DOI : 10.1093/mam/ozaf048.1126.A Comparative Analysis of STEM Phase Retrieval Techniques: Evaluating Transfer of Information and Dose Efficiency
Microscopy and Microanalysis. 2025. Vol. 31, num. Supplement_1. DOI : 10.1093/mam/ozaf048.1113.Studying Sars-cov-2 Ssrna Key Sequence Combining Fourier Transform Infrared Spectroscopy and Theoretical Folding Model
EUROPEAN BIOPHYSICS JOURNAL. 2025. DOI : 10.1007/s00249-025-01766-8.Arrestin recognizes GPCRs independently of the receptor state
Proceedings of the National Academy of Sciences. 2025. Vol. 122, num. 20. DOI : 10.1073/pnas.2501487122.Effect of surfactants on inactivation of Bacillus subtilis spores by chlorine
Water Research. 2025. Vol. 272, p. 122944. DOI : 10.1016/j.watres.2024.122944.Structural basis of SIRT7 nucleosome engagement and substrate specificity
NATURE COMMUNICATIONS. 2025. Vol. 16, num. 1. DOI : 10.1038/s41467-025-56529-y.Identification of a binding site for small molecule inhibitors targeting human TRPM4
NATURE COMMUNICATIONS. 2025. Vol. 16, num. 1. DOI : 10.1038/s41467-025-56131-2.Conference Papers
ViPer: Visual Personalization of Generative Models via Individual Preference Learning
2025. 18th European Conference on Computer Vision, Milan, Italy, 2024-09-29 – 2024-10-04. p. 391 – 406. DOI : 10.1007/978-3-031-72904-1_23.Reviews
Correlative light and electron microscopy for human brain and other biological models
NATURE PROTOCOLS. 2025. DOI : 10.1038/s41596-025-01153-9.Theses
An investigation of pathological tau aggregates in the postmortem human brain tissue of Alzheimer’s disease patients using correlative light and electron microscopy
Lausanne, EPFL, 2025.Structural investigations of brain and skin tissues in Parkinson’s and related diseases, using correlative light and electron microscopy
Lausanne, EPFL, 2025.2024
Journal Articles
Ultrastructural characterization of tau pathology in the human post‐mortem Alzheimer’s disease brain
Alzheimer’s & Dementia. 2024. Vol. 20, num. S8. DOI : 10.1002/alz.094941.Low-dose cryo-electron ptychography of proteins at sub-nanometer resolution
Nature communications. 2024. Vol. 15, num. 1. DOI : 10.1038/s41467-024-52403-5.Modulation of ABCG2 Transporter Activity by Ko143 Derivatives
ACS chemical biology. 2024. Vol. 19, num. 11, p. 2304 – 2313. DOI : 10.1021/acschembio.4c00353.Mouse α-synuclein fibrils are structurally and functionally distinct from human fibrils associated with Lewy body diseases
Science advances. 2024. Vol. 10, num. 44. DOI : 10.1126/sciadv.adq3539.Cryo-electron microscopy in color
NATURE METHODS. 2024. Vol. 21, num. 12. DOI : 10.1038/s41592-024-02427-y.Automated fiducial-based alignment of cryo-electron tomography tilt series in Dynamo
STRUCTURE. 2024. Vol. 32, num. 10. DOI : 10.1016/j.str.2024.07.003.Rapid iPSC inclusionopathy models shed light on formation, consequence, and molecular subtype of α-synuclein inclusions
Neuron. 2024. Vol. 112, num. 17, p. 2886 – 2909.e16. DOI : 10.1016/j.neuron.2024.06.002.Inverse Applications of the Generalized Littlewood Theorem Concerning Integrals of the Logarithm of Analytic Functions
Symmetry. 2024. Vol. 16, num. 9, p. 1100. DOI : 10.3390/sym16091100.Optical Nanomotion Detection to Rapidly Discriminate between Fungicidal and Fungistatic Effects of Antifungals on Single-Cell Candida albicans
Antibiotics. 2024. Vol. 13, num. 8. DOI : 10.3390/antibiotics13080712.Hierarchical Protofilament Intertwining Rules the Formation of Mixed‐Curvature Amyloid Polymorphs
Advanced Science. 2024. Vol. 11, num. 32. DOI : 10.1002/advs.202402740.Three-Dimensional Electrode Integration With Microwave Sensors for Precise Microparticle Detection in Microfluidics
IEEE SENSORS JOURNAL. 2024. Vol. 24, num. 10, p. 16085 – 16092. DOI : 10.1109/JSEN.2024.3384984.Editorial: New marketable discoveries in nanobiotechnology
Frontiers In Bioengineering And Biotechnology. 2024. Vol. 12, p. 1412587. DOI : 10.3389/fbioe.2024.1412587.Accurate and rapid antibiotic susceptibility testing using a machine learning-assisted nanomotion technology platform
Nature Communications. 2024. Vol. 15, num. 1, p. 2037. DOI : 10.1038/s41467-024-46213-y.Cellular nanomotion as a new signature of life
Frontiers in Microbiology. 2024. Vol. 15, p. 1390002. DOI : 10.3389/fmicb.2024.1390002.A simplified version of rapid susceptibility testing of bacteria and yeasts using optical nanomotion detection
Frontiers in Microbiology. 2024. Vol. 15, p. 1328923. DOI : 10.3389/fmicb.2024.1328923.Machine learning method for the classification of the state of living organisms’ oscillations
Frontiers In Bioengineering And Biotechnology. 2024. Vol. 12, p. 1348106. DOI : 10.3389/fbioe.2024.1348106.On the Sums over Inverse Powers of Zeros of the Hurwitz Zeta Function and Some Related Properties of These Zeros
Symmetry-basel. 2024. Vol. 16, num. 3, p. 326. DOI : 10.3390/sym16030326.Structure-function analysis of the cyclic β-1,2-glucan synthase from Agrobacterium tumefaciens
Nature Communications. 2024. Vol. 15, num. 1, p. 1844. DOI : 10.1038/s41467-024-45415-8.An Optical Fiber-Based Nanomotion Sensor for Rapid Antibiotic and Antifungal Susceptibility Tests
Nano Letters. 2024. DOI : 10.1021/acs.nanolett.3c03781.Author Correction: Fully co-factor-free ClearTau platform produces seeding-competent Tau fibrils for reconstructing pathological Tau aggregates
Nature Communications. 2024. Vol. 15, num. 1. DOI : 10.1038/s41467-024-48976-w.Computational drug development for membrane protein targets
Nature Biotechnology. 2024. Vol. 42, num. 2, p. 229 – 242. DOI : 10.1038/s41587-023-01987-2.Distinct ultrastructural phenotypes of glial and neuronal alpha-synuclein inclusions in multiple system atrophy
Brain. 2024. Vol. awae137. DOI : 10.1093/brain/awae137.Conference Papers
Joint Ptychographic Tomography of Frozen Hydrated Proteins
2024. The 17th European Microscopy Congress, Copenhagen, Denmark, 2024-08-25 – 2024-08-30. DOI : 10.1051/bioconf/202412911005.Theses
Disentangling Multiple System Atrophy – Structural insights from alpha-synuclein fibrils and tissue pathology
Lausanne, EPFL, 2024.Working Papers
1.94 Å structure of synthetic α-synuclein fibrils seeding MSA neuropathology
2024
Mouse α-synuclein fibrils are structurally and functionally distinct from human fibrils associated with Lewy body diseases
2024
2023
Journal Articles
Structural basis of bile salt extrusion and small-molecule inhibition in human BSEP
Nature Communications. 2023. Vol. 14, num. 1, p. 7296. DOI : 10.1038/s41467-023-43109-1.Candida albicans Adhesion Measured by Optical Nanomotion Detection
Fermentation-Basel. 2023. Vol. 9, num. 11, p. 991. DOI : 10.3390/fermentation9110991.Mechanical Properties and Nanomotion of BT-20 and ZR-75 Breast Cancer Cells Studied by Atomic Force Microscopy and Optical Nanomotion Detection Method
Cells. 2023. Vol. 12, num. 19, p. 2362. DOI : 10.3390/cells12192362.Structural Basis of the Allosteric Inhibition of Human ABCG2 by Nanobodies
Journal of Molecular Biology. 2023. Vol. 435, num. 19, p. 168234. DOI : 10.1016/j.jmb.2023.168234.Fully co-factor-free ClearTau platform produces seeding-competent Tau fibrils for reconstructing pathological Tau aggregates
Nature Communications. 2023. Vol. 14, num. 1, p. 3939. DOI : 10.1038/s41467-023-39314-7.Activation mechanism of a short argonaute-TIR prokaryotic immune system
Science Advances. 2023. Vol. 9, num. 29, p. eadh9002. DOI : 10.1126/sciadv.adh9002.Genomic screening of 16 UK native bat species through conservationist networks uncovers coronaviruses with zoonotic potential
Nature Communications. 2023. Vol. 14, num. 1, p. 3322. DOI : 10.1038/s41467-023-38717-w.On the Applications of the Generalized Littlewood Theorem Concerning Integrals of the Logarithm of Analytical Functions to Elliptic Functions
Axioms. 2023. Vol. 12, num. 6, p. 595. DOI : 10.3390/axioms12060595.Secondary Structures of MERS-CoV, SARS-CoV, and SARS-CoV-2 Spike Proteins Revealed by Infrared Vibrational Spectroscopy
International Journal Of Molecular Sciences. 2023. Vol. 24, num. 11, p. 9550. DOI : 10.3390/ijms24119550.De novo design of protein interactions with learned surface fingerprints
Nature. 2023. Vol. 617, num. 7959, p. 176 – 184. DOI : 10.1038/s41586-023-05993-x.Simple optical nanomotion method for single-bacterium viability and antibiotic response testing
Proceedings Of The National Academy Of Sciences Of The United States Of America (PNAS). 2023. Vol. 120, num. 18, p. e2221284120. DOI : 10.1073/pnas.2221284120.Cryo-EM structures and binding of mouse and human ACE2 to SARS-CoV-2 variants of concern indicate that mutations enabling immune escape could expand host range
PLOS Pathogens. 2023. Vol. 19, num. 4, p. e1011206. DOI : 10.1371/journal.ppat.1011206.Single-Cell Optical Nanomotion of Candida albicans in Microwells for Rapid Antifungal Susceptibility Testing
Fermentation-Basel. 2023. Vol. 9, num. 4, p. 365. DOI : 10.3390/fermentation9040365.Mitochondrial nanomotion measured by optical microscopy
Frontiers in Microbiology. 2023. Vol. 14, p. 1133773. DOI : 10.3389/fmicb.2023.1133773.Modulation of the nanoscale motion rate of Candida albicans by X-rays
Frontiers in Microbiology. 2023. Vol. 14, p. 1133027. DOI : 10.3389/fmicb.2023.1133027.Fast Self-Assembly Dynamics of a beta-Sheet Peptide Soft Material
Small. 2023. DOI : 10.1002/smll.202206795.Structural and molecular determinants for the interaction of ExbB from Serratia marcescens and HasB, a TonB paralog (vol 5, 355, 2022)
Communications Biology. 2023. Vol. 6, num. 1, p. 67. DOI : 10.1038/s42003-022-04256-1.Structure of a membrane-bound menaquinol:organohalide oxidoreductase
Nature Communications. 2023. Vol. 14, p. 7038. DOI : 10.1038/s41467-023-42927-7.On the Use of the Generalized Littlewood Theorem Concerning Integrals of the Logarithm of Analytical Functions for the Calculation of Infinite Sums and the Analysis of Zeroes of Analytical Functions
Axioms. 2023. Vol. 12, num. 1, p. 68. DOI : 10.3390/axioms12010068.Conference Papers
Machine Learning in Protein Science De Novo Design of Site-Specific Protein Binders Using Surface Fingerprints
2023. 36th Annual Symposium of the Protein-Society, San Francisco, CA, Jul 07-10, 2022.2022
Journal Articles
Mechanism ofcyclic beta-glucan export by ABC transporter Cgt of Brucella
Nature Structural & Molecular Biology. 2022. DOI : 10.1038/s41594-022-00868-7.An Inertial Uni-Axial Interferometer-Based Accelerometer for Harsh Environments
Ieee Sensors Journal. 2022. Vol. 22, num. 22, p. 21540 – 21549. DOI : 10.1109/JSEN.2022.3210369.Allosteric control of type I-A CRISPR-Cas3 complexes and establishment as effective nucleic acid detection and human genome editing tools
Molecular Cell. 2022. Vol. 82, num. 15, p. 2754 – +. DOI : 10.1016/j.molcel.2022.06.007.Strontium Substituted Tricalcium Phosphate Bone Cement: Short and Long-Term Time-Resolved Studies and In Vitro Properties
Advanced Materials Interfaces. 2022. p. 2200803. DOI : 10.1002/admi.202200803.The Dynamics of Single-Cell Nanomotion Behaviour of Saccharomyces cerevisiae in a Microfluidic Chip for Rapid Antifungal Susceptibility Testing
Fermentation-Basel. 2022. Vol. 8, num. 5, p. 195. DOI : 10.3390/fermentation8050195.Structural and molecular determinants for the interaction of ExbB from Serratia marcescens and HasB, a TonB paralog
Communications Biology. 2022. Vol. 5, num. 355. DOI : 10.1038/s42003-022-03306-y.Cryo-EM structures of a LptDE transporter in complex with Pro-macrobodies offer insight into lipopolysaccharide translocation
Nature Communications. 2022. Vol. 13, p. 1826. DOI : 10.1038/s41467-022-29459-2.Trans‐seeding of Alzheimer‐related tau protein by a yeast prion
Alzheimer’s & Dementia. 2022. p. 1 – 12. DOI : 10.1002/alz.12581.2.4-angstrom structure of the double-ring Gemmatimonas phototrophica photosystem
Science Advances. 2022. Vol. 8, num. 7, p. eabk3139. DOI : 10.1126/sciadv.abk3139.Cryo-EM structure of native human thyroglobulin
Nature Communications. 2022. Vol. 13, p. 61. DOI : 10.1038/s41467-021-27693-8.Datasets
mouse ACE2 receptor bound to SARS-CoV-2 variant Omicron BA.2.12.1 Spike
2022.mouse ACE2 receptor bound to SARS-CoV-2 variant Beta Spike
2022.mouse ACE2 receptor bound to SARS-CoV-2 variant Omicron BA.1 Spike
2022.2021
Journal Articles
FTLD-TDP assemblies seed neoaggregates with subtype-specific features via a prion-like cascade
Embo Reports. 2021. p. e53877. DOI : 10.15252/embr.202153877.Nanomechanical bio-sensing for fast and reliable detection of viability and susceptibility of microorganisms
Sensors and Actuators B: Chemical. 2021. Vol. 348, p. 130650. DOI : 10.1016/j.snb.2021.130650.Nanomotion Spectroscopy as a New Approach to Characterize Bacterial Virulence
Microorganisms. 2021. Vol. 9, num. 8, p. 1545. DOI : 10.3390/microorganisms9081545.Structures of ABCG2 under turnover conditions reveal a key step in the drug transport mechanism
Nature Communications. 2021. Vol. 12, num. 1, p. 4376. DOI : 10.1038/s41467-021-24651-2.Identification of a Dps contamination in Mitomycin-C–induced expression of Colicin Ia
Biochimica et Biophysica Acta (BBA) – Biomembranes. 2021. Vol. 1863, num. 7, p. 183607. DOI : 10.1016/j.bbamem.2021.183607.Structural basis of the activation of the CC chemokine receptor 5 by a chemokine agonist
Science Advances. 2021. Vol. 7, num. 25, p. eabg8685. DOI : 10.1126/sciadv.abg8685.Structural basis of drug recognition by the multidrug transporter ABCG2
Journal of Molecular Biology. 2021. Vol. 433, num. 13, p. 166980. DOI : 10.1101/2021.02.18.431786.Functional and structural characterization of Serratia marcescens ExbB: determinants of the interaction with HasB/TonB
bioRxiv. 2021. Vol. 2021.04.21.440815. DOI : 10.1101/2021.04.21.440815.Nano-Motion Analysis for Rapid and Label Free Assessing of Cancer Cell Sensitivity to Chemotherapeutics
Medicina-Lithuania. 2021. Vol. 57, num. 5, p. 446. DOI : 10.3390/medicina57050446.Insight into Lipopolysaccharide Translocation by Cryo-EM structures of a LptDE Transporter in Complex with Pro-Macrobodies
bioRxiv. 2021. Vol. 2021.03.23.436624. DOI : 10.1101/2021.03.23.436624.Nanophotonic structures with optical surface modes for tunable spin current generation
Nanoscale. 2021. Vol. 13, num. 11, p. 5791 – 5799. DOI : 10.1039/d0nr08692d.Sensing of Surface and Bulk Refractive Index Using Magnetophotonic Crystal with Hybrid Magneto-Optical Response
Sensors. 2021. Vol. 21, num. 6, p. 1984. DOI : 10.3390/s21061984.Coordination-Driven Monolayer-to-Bilayer Transition in Two-Dimensional Metal–Organic Networks
The Journal of Physical Chemistry B. 2021. Vol. 125, num. 16, p. 4204 – 4211. DOI : 10.1021/acs.jpcb.1c01058.Environmental Control of Amyloid Polymorphism by Modulation of Hydrodynamic Stress
Acs Nano. 2021. Vol. 15, num. 1, p. 944 – 953. DOI : 10.1021/acsnano.0c07570.Single Particle Analysis for High-Resolution 2D Electron Crystallography
Methods in Molecular Biology. 2021. Vol. 2215, p. 267 – 284. DOI : 10.1007/978-1-0716-0966-8_12.Conference Papers
Ultrasensitive Optical Label-Free Biosensing and Fluorescent Measurements using UV Surface Plasmons in Gold Nanolayers Launched with the Support of a Specially Designed Photonic Crystal
2021. p. 364A – 364A. DOI : 10.1016/j.bpj.2020.11.2247.Reviews
Structural strains of misfolded tau protein define different diseases
Nature. 2021. Vol. 598, num. 7880, p. 264 – 265. DOI : 10.1038/d41586-021-02611-6.Nanomotion Detection-Based Rapid Antibiotic Susceptibility Testing
Antibiotics. 2021. Vol. 10, num. 3, p. 287. DOI : 10.3390/antibiotics10030287.Working Papers
Cryo-EM structure of native human thyroglobulin
2021