Our publications 2024Journal Articles The CRL5-SPSB3 ubiquitin ligase targets nuclear cGAS for degradationP. Xu; Y. Liu; C. Liu; B. Guey; L. Li et al. Nature. 2024. DOI : 10.1038/s41586-024-07112-w. Detailed record View at publisher 2023Journal Articles PSGL-1 is an evolutionarily conserved antiviral restriction factorC. Jiang; M. Mei; Y. Liu; M. Hou; J. Jiao et al. Mbio. 2023. p. e0038723. DOI : 10.1128/mbio.00387-23. Detailed record View at publisher Inflammatory mitochondrial nucleic acids as drivers of pathophysiologyC. G. Peace; A. Hooftman; D. G. Ryan Clinical And Translational Medicine. 2023. Vol. 13, num. 9, p. e1403. DOI : 10.1002/ctm2.1403. Detailed record View at publisher cGAS-STING drives ageing-related inflammation and neurodegenerationM. F. Gulen; N. Samson; A. Keller; M. Schwabenland; C. Liu et al. Nature. 2023. Vol. 620, p. 374 – 380. DOI : 10.1038/s41586-023-06373-1. Detailed record View at publisher 2022Journal Articles Colon tumour cell death causes mTOR dependence by paracrine P2X4 stimulationM. Schmitt; F. Ceteci; J. Gupta; M. Pesic; T. W. Bottger et al. Nature. 2022. Vol. 612, p. 347 – 353. DOI : 10.1038/s41586-022-05426-1. Detailed record View at publisher Clathrin-associated AP-1 control stermination of STING signallingY. Liu; P. Xu; S. Rivara; C. Liu; J. Ricci et al. Nature. 2022. Vol. 610, num. 7933, p. 761 – 767. DOI : 10.1038/s41586-022-05354-0. Detailed record View at publisher Monocyte-derived macrophages aggravate pulmonary vasculitis via cGAS/STING/IFN-mediated nucleic acid sensingN. Kessler; S. F. Viehmann; C. Krollmann; K. Mai; K. M. Kirschner et al. Journal Of Experimental Medicine. 2022. Vol. 219, num. 10, p. e20220759. DOI : 10.1084/jem.20220759. Detailed record View at publisher 2021Journal Articles DNA hypomethylation leads to cGAS-induced autoinflammation in the epidermisM. A. Beck; H. Fischer; L. M. Grabner; T. Groffics; M. Winter et al. Embo Journal. 2021. p. e108234. DOI : 10.15252/embj.2021108234. Detailed record View at publisher Bio-orthogonal Red and Far-Red Fluorogenic Probes for Wash-Free Live-Cell and Super-resolution MicroscopyP. Werther; K. Yserentant; F. Braun; K. Grussmayer; V. Navikas et al. Acs Central Science. 2021. Vol. 7, num. 9, p. 1561 – 1571. DOI : 10.1021/acscentsci.1c00703. Detailed record View at publisher Clinical trials of mTOR inhibitors to boost immunity to viral infection in older adultsP. J. Dzankic; L. Partridge Lancet Healthy Longevity. 2021. Vol. 2, num. 5, p. E232 – E233. DOI : 10.1016/S2666-7568(21)00090-8. Detailed record View at publisher The spatial organization of cGAS-TREX1 interactionsP. Juricic; A. Ablasser Developmental Cell. 2021. Vol. 56, num. 7, p. 876 – 877. DOI : 10.1016/j.devcel.2021.03.016. Detailed record View at publisher DNA sensor in standby mode during mitosisA. Ablasser Science. 2021. Vol. 371, num. 6535, p. 1204 – 1205. DOI : 10.1126/science.abg7422. Detailed record View at publisher m6A methylation potentiates cytosolic dsDNA recognition in a sequence-specific mannerM. Balzarolo; S. Engels; A. J. de Jong; K. Franke; T. K. van den Berg et al. Open Biology. 2021. Vol. 11, num. 3, p. 210030. DOI : 10.1098/rsob.210030. Detailed record View at publisher 2020Journal Articles COPA silences STINGS. Rivara; A. Ablasser Journal Of Experimental Medicine. 2020. Vol. 217, num. 11, p. e20201517. DOI : 10.1084/jem.20201517. Detailed record View at publisher BAF restricts cGAS on nuclear DNA to prevent innate immune activationB. Guey; M. Wischnewski; A. Decout; K. Makasheva; M. Kaynak et al. Science. 2020. Vol. 369, num. 6505, p. 823 – 828. DOI : 10.1126/science.aaw6421. Detailed record View at publisher Editorial overview ‘Network news: Reporting from the frontlines of cell signaling’A. Ablasser; J. Thorner Current Opinion In Cell Biology. 2020. Vol. 63, p. III – V. DOI : 10.1016/j.ceb.2020.02.013. Detailed record View at publisher Structural mechanism of cGAS inhibition by the nucleosomeG. R. Pathare; A. Decout; S. Glück; S. Cavadini; K. Makasheva et al. Nature. 2020. Vol. 587, p. 668 – 672. DOI : 10.1038/s41586-020-2750-6. Detailed record View at publisher 2019Journal Articles Latest advances in aging research and drug discoveryD. Bakula; A. Ablasser; A. Aguzzi; A. Antebi; N. Barzilai et al. Aging-Us. 2019. Vol. 11, num. 22, p. 9971 – 9981. DOI : 10.18632/aging.102487. Detailed record View at publisher A carrier for cyclic dinucleotidesB. Guey; A. Ablasser Nature Immunology. 2019. Vol. 20, num. 11, p. 1418 – 1420. DOI : 10.1038/s41590-019-0521-z. Detailed record View at publisher Virology: Poxins Soothe the STINGA. Decout; A. Ablasser Current Biology. 2019. Vol. 29, num. 9, p. R332 – R334. DOI : 10.1016/j.cub.2019.03.031. Detailed record View at publisher
