Schueder Lab – Molecular Spatial Omics

Imaging pearls

As Richard Feynman observed in 1959, ‘There’s plenty of room at the bottom.’ Six decades on, the vast microscopic landscape of biology still teems with unanswered questions.

Our lab investigates how the spatial arrangement of biomolecules, from the molecular scale up to the mesoscale, drives biological function.

By inventing and applying cutting‑edge imaging hardware, DNA nanotechnology, and computational tools, we aim to reveal the principles that link molecular architecture to cellular and tissue‑level behavior, enabling new insights across microbiology, systems biology, and beyond.

The Schueder lab will open in January 2026!

We are looking for two passionate and driven graduate students to contribute to interdisciplinary projects. The ideal candidate is passionate about multiple – ideally all – of the following areas of research:

  • Nanotechnology: Design of new DNA-based imaging probes and the use of DNA origami
    nanotechnology to benchmark newly developed probes.
  • Biochemistry: Design, construction, and validation of novel binders for labeling and imaging cellular
    proteins, RNA, and DNA.
  • Optics & Microfluidics: Development of custom microscopy setups and microfluidic systems to
    leverage the full potential of smart probe microscopy.
  • Computation: Development of new workflows to analyze, interpret, and model the high-dimensional spatial omics data we acquire.